INNOVATIONS IN ANIMAL FEED (ADDITIVES) - LEON MARCHAL, PHD INNOVATION DIRECTOR PACCARB, WASHINGTON 27TH FEBRUARY 2020 - HHS.GOV
←
→
Page content transcription
If your browser does not render page correctly, please read the page content below
Innovations in Animal Feed (Additives) PACCARB, Washington 27th February 2020 Leon Marchal, PhD Innovation Director
Dupont Animal Nutrition, part of Nutrition & Biosciences
Porzyme® &
Avizyme®
Feed enzyme First species- Phyzyme® XP Phyzyme® XP TPT Enviva® EO Axtra® PHY Syncra® AVI Axtra® PRO
development specific multi- First E. coli Porcheck® launch Fastest enzyme-probiotic Leading
begins enzyme solutions phytase software tool phytogenic blend phytase combination protease
1982 1988 2003 2007 2010 2013 2015 2018
1979 1984 1997 2006 2008 2011 2014 2017 2019
Betafin® First Avizyme® 1500 Avicheck® MicroTreat Axtra® XB Optimize Enviva® PRO CSI 2.0
First betaine for ß-glucanase Carbohydrase/ Phycheck® P Provalen Axtra® XAP Feed® Service Probiotic for Fecal microbial
Choline sparing enzyme protease blend services Probiotics for Carbohydrases broilers analysis
poultry for complex diets Syncra® SWI service for
CSI - Gut Adaptive protease/ poultry and
microbial analysis probiotic solution swine
service for poultry
and swine
Fundamental understanding of
nutritional processes and
the effects on the health, growth, welfare
and longevity of animals.
Animal Nutrition group of Wageningen University
2
What needs to happen for
antibiotic (growth promotor) free production
Nutrition
Gut & Immune
Microbiome
Function
Image: Ted
Hygiene
3
Feed structure – better organ development
Experimental group
Control (starconcept 0%)
100% diet 100% diet Trial (starconcept 15%)
Grinding Grinding
Similar feed conversion
15% whole grain
Better stomach function
Pelleting Pelleting Less prone to
Salmonella infections
Images: ForFarmers
Stomach Score
Adding a few % fiber structure to
a broiler diet Reviews
The gizzard: function, influence of diet
Better organ development
structure and effects on nutrient
Beneficial for ‘right flora in
availability
the right place’
B.SVIHUS
Same or better feed
Department of Animal and Aquacultural Sciences, conversion
Norwegian University of Life Sciences,
Image:Nutreco World's Poultry Science Journal, Vol. 67, June 2011
4
Less overfeeding of protein
• Protein digestion is generally 60-90%
• Younger animals have generally lower digestibility
• Raw material quality also varies in practice
All the protein that is not
digested in the small
intestine is potentially
fermented by pathogens
in the large intestine
Protein digestion kinetics in pigs and poultry, H.Chen (2017) 5Hydrolytic enzymes improve (protein) digestibility
• Phytases are the most commonly used enzyme, globally
• Competition drives increased efficacy & reduced costs higher inclusion levels
P linear < 0.0001 83
187
82 E-Coli
% 81 186 Buttiauxella
Amino acid digestibility
Amino acid digestibility
185
79
(g/kg diet)
184
78
77 183
182
181
180
179
PC NC 250 500 1000 2000 0 250 500 750 1000 1250 1500 1750 2000
Phytase, FTU/kg Phytase dose (FTU/kg feed)
Animal Feed Science and Technology 253 (2019) 166–180
J. Anim. Sci. 2019.97:2524–2533
Other enzymes used in animal production: xylanases, beta-glucanases, amylases, proteases
6DFM / probiotic maintain general gastrointestinal health
Immuno Stimulate
modulation immune
response
Stimulate Regulate
defense by proinflammatory
host cytokines
Compete for
nutrients
Competitive Enhance
exclusion beneficial
microbiota
Compete for
ecological Decrease
niches luminal pH
Inhibition of
virulence
factors
Direct
microbial
interactions
Secrete
bacteriocidal
molecules
7What are DFM / probiotics capable of?
Probiotics can Probiotics are
Support the development of a healthy gut
NOT a drug
(immune system, gut function and
microbiota development) NOT a true replacement for
therapeutic antibiotics
Support the recovery post-infection
Can have antimicrobial activity against
other microbes (typically broad spectrum)
Add to the overall fermentation and can
produce beneficial metabolites
8Innovations in Animal Feed (Additives)
A combination of feed additives and feeding
more precisely can reduce the need of
antibiotics drastically
(EU and market examples).
Further antibiotic reduction needs the
development of more consistent feed
additive solutions.
Key is increasing the robustness of the
animals.
We should conserve the efficacy of
antibiotics for when they are really needed
when animals despite all measures
become sick (animal welfare).
9Copyright © 2020 DuPont. All rights reserved. DuPont™, the DuPont logo and all products denoted with ® or ™ are trademarks of the affiliates of DuPont de Nemours, Inc. The information contained herein is subject to change without further notice, is provided at the request of and without charge to our customers and is based upon data DuPont believes to be reliable. Conditions and methods of use of the products are beyond our control, and nothing contained herein shall be construed as a representation or warranty on use or of non-infringement of intellectual property, regulatory or legal compliance. If this presentation is provided in any language other than English, the original English version will control, and DuPont hereby disclaims responsibility for any errors caused by translation.
You can also read
