THEORETICAL-PRACTICAL COURSE

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THEORETICAL-PRACTICAL COURSE

                                       June 22nd -23rd, 2022

                                 POLO DIDATTICO ALBERTI
                                   Via Alberti, 2 Genova

                                          ECM credits: 15.2 1

    The course aims at providing an update on alternative methods for animal
    testing, in the context of risk identification in cosmetics, and adhering to

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    For: Medical doctors, Veterinarians, Biologists, Chemists, Pharmacists, Biomedical Laboratory Technicians.

                                                      -1-
European Regulations placing a complete ban on animal testing for
 cosmetic purposes (CE n. 1223/2009).
 The Regulation improves the safety of cosmetic products sold in EU by
 strengthening their safety requirements. It simplifies procedures for
 companies and competent authorities in the sector, updates the rules for
 taking into account the latest technological developments, including the
 possible use of nanomaterials, and keeps the ban on animal testing in
 place.

 To this end, it is crucial to provide an understanding of the scientific bases
 of these regulations and up-to-date information to students in biomedical
 sciences. It is also important to contribute to the training of
 technicians/researchers already operating in the cosmetic industry,
 emphasizing aspects of eco-sustainability. Finally, the consolidation of
 collaborations between biologists, chemists, ecologists is a must.
 The course is run by the Italian Centro3R, Interuniversity Center of the
 Promotion of the 3R Principles in Teaching and Research.

Sponsors:

                                            -2-
JUNE 22nd
           GIUGNO
 8.30 – 9.30
                                                         SPEAKER
                                                 Registrazione
                                                                          AFFILIATION

                      Introduzione al corso
                                                      Arti Ahluwalia    Università di Pisa
9.30 – 10.00        Centro3R impegno nella                             Politecnico di Torino
                                                      Valeria Chiono
                          formazione                                         Centro3R

                      Irritazione e Corrosione
10.00 -10.30    nell’ambito del Regolamento CLP          Tomaso            IA Industria
                     Irritazione e Corrosione            Munari             Ambiente
10.30 -11.00    nell’ambito della normativa rifiuti

                      Conflitto tra REACH e                              CAAT-Europe:
                   regolamento cosmetici per             Maria
                                                                            Centre of
11.00 - 11.30      quanto riguarda i test sugli         Costanza
                                                                         Alternatives to
                              animali                    Rovida
                                                                         Animal Testing
11.30 -12.00                                      Coffee break
                In vitro skin irritation tests using
                reconstructed human epidermis            Jan Markus     MatTek In Vitro Life
12.00 - 12.45
                         model EpiDerm                                 Science Laboratories

                  Skin sensitization: validated
12.45 - 13.15      alternatives and defined           Laura Ceriotti       VitroScreen
                          approaches

13.15-13.45                                      Q&A session
13.45- 14.45                                       LUNCH
                The GARD assay for sensitization
                                                          Andy
14.45 -15.15      hazard identification and risk                            SenzaGen
                                                         Forreryd
                           assessment

                 From AOPs (Adverse Outcome
                                                                          CAAT-Europe:
                Pathways) to the next generation          Maria
                                                                            (Centre of
15.15 - 15.45    risk assessment (NGRA) for the          Costanza
                                                                          Alternatives to
                      final goal of full animal           Rovida
                                                                          Animal Testing)
                    replacement in toxicology

15.45-16.20                           Coffee break – Q&A session
                  EpiDerm Skin irritation test
16.30-18.30       according to OECD TG 439           Jan Markus              MatTek
                          (Training)

                                           -3-
JUNE 23rd
                                                               SPEAKER         AFFILIATION
                 Estrazioni microonde ecosostenibili di                         Università di
 9.30-10.00          ingredienti cosmetici da scarti           Carla Villa        Genova
                                agrifood                                         Centro3R
                  Grape-derived extracts as potential
                  active pharmaceutical and cosmetic                          Istituto Italiano di
10.00-10.30                                                 Gianni Ciofani
                              ingredients                                         Tecnologia

                                                                                Politecnico di
                  Advanced wound dressings and                                      Torino
10.30-11.00                                                Rossella Laurano
                 models for their preclinical validation
                                                                                  Centro3R

11.00 – 11.30                             Coffee Break – Q&A SESSION
                    The assessment of eye irritation
                 potential of chemicals, cosmetics, and                        MatTek In Vitro
11.30-12.15           household products using            Silvia Letasiava      Life Science
                   reconstructed human cornea-like                              Laboratories
                            model EpiOcular

                                                                                 Università di
                    Il packaging in cosmetica: ruolo
12.15 - 12.45                                                  Carla Villa         Genova
                           interazioni e trend
                                                                                  Centro3R
                  A new and highly representative in
12.45– 13.15                                               Tommaso Sbrana           IvTech
                      vitro model of human skin
13.15 – 14.15                                          Lunch
                  Rilevanza dei sistemi sperimentali in        Emma Di        Istituto Superiore
14.15 – 14.45    vitro e fattori che possono influenzare       Consiglio              Sanità
                          l'outcome dello studio.
                                                                              Università di Pisa
                    Modelli in silico al supporto dei      Chiara Magliaro
14.45 - 15.15
                            modelli in vitro                                      Centro3R

                 EpiOcular Eye Irritation test according  Silvia Letasiova         MatTek
15.30 – 17.00
                     to OECD TG 492 (Training)
                                                   Q&A session
                                                                                Università di
                                                           Anna Maria Bassi        Genova
17.00 – 18.00                Final remarks
                                                                                  Centro3R

                                                Exam for the ECM

                                              -4-
REGISTRATION FEES (VAT included)

                    € 250 (with ECM), € 150 (without ECM)

Increased by € 30 after June 7th, 2002.

The fee includes course participation, conference kit, teaching materials (digital and
paper copy), participation certificate, coffee breaks and lunches.

Maximum number of particpants: 402. Minimum number: 14.

REGISTRATION
    o Online until 7/06/2022, from the website of Centro 3R, and filling in the form.
    o After confirming the registration, the fee has to be paid through Bank Transfer,
      payable to: Ggallery srl – Banco di Credito P. Azzoalio, Filiale di Cengio (SV),
      Via Bagnolo 1, 17056 IBAN IT87Z0342549370CC0260111990, Re:
      APPLICAZIONE DI MODELLI SOSTITUTIVI ALL’ANIMALE NELL’AMBITO
      COSMETOLOGICO
    o The receipt of the payment has to be sent by 07/06/2022, via email
      (moira.nevins@gallerygroup.it) or in person to Ggallery srl – Piazza Manin 2 b-r,
      Opening hours: 9 - 18 (parking available)

    SCIENTIFIC & ORGANISING COMMITTEE

       Anna Maria Bassi, Susanna Penco, Carla Villa, Stefania
       Vernazza, Sara Tirendi, Vanessa Almonti, Chiara Magliaro,
       Irene Carmagnola

                                                                info@centro3r.it,
                         anna.maria.bassi@unige.it, susanna.penco@unige.it

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 If necessary, participants will be selected on the basis of their experience with basic cell
culture techniques.
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