DELIVERING PANDEMIC RESILIENCE REVISITED - Bottlenecks to breakthroughs: What we've learned one year into COVID-19 and how we'll be ready for the ...
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CONFIDENTIAL DELIVERING PANDEMIC RESILIENCE REVISITED Bottlenecks to breakthroughs: What we’ve learned one year into COVID-19 and how we’ll be ready for the next health emergency DHL CSI – Customer Solutions and Innovation
CONFIDENTIAL Revisiting Pandemic Resilience in a nutshell Out of the It’s a marathon, not a The home Getting ready for starting blocks sprint stretch the next race DHL CSI – Customer Solutions & Innovation | Bonn | June 2021 2
CONFIDENTIAL CHAPTER 1: Out of the starting blocks Out of the It’s a marathon, not a The home Getting ready for starting blocks sprint stretch the next race DHL CSI – Customer Solutions & Innovation | Bonn | June 2021 3
CONFIDENTIAL Although the last year was difficult, there are ten key achievements of the global community Deep Dive on following slides 1 COVID-19 vaccine 2 Two new vaccine 3 Total global 4 The complex 5 Extreme development platforms, that can vaccine production global vaccine cold-chain occurred five times tackle diseases quadrupled supply chain was requirements faster than any other beyond COVID-19, within a year ramped-up were met at scale vaccine in history have emerged and successfully – flawlessly! begun to mature 6 The vaccination 7 Multilateral action 8 Vaccine economics 9 Markets quickly 10 Large-scale rate already was taken to work: on a per met the high research on outpaces the ensure global capita basis end-to- demand for therapeutics infection rate by a access to end costs for testing, ancillary has been factor of nine vaccines vaccination equal supplies, and PPE promising just one week of lockdown costs DHL CSI – Customer Solutions & Innovation | Bonn | June 2021 4
CONFIDENTIAL 1 COVID-19 vaccine development occurred five times faster than any other vaccine in history Vaccination innovation Time from infectious agent identification to vaccine approval in the US, years 5x faster 0.8 4 10 16 25 33 43 COVID-19 Mumps 1 Measles Hepatitis B Human Diarrheal Ebola papillomavirus disease 1: Note that COVID-19 vaccines have received Emergency Use Approval, whereas the other vaccines have received biologics license application approval in the stated time. Source: Bernadeta Dadonaite, Max Roser, and Samantha Vanderslott, “Vaccination,” Our World in Data; “COVID-19 vaccines,” US Food and Drug Administration, fda.gov DHL CSI – Customer Solutions & Innovation | Bonn | June 2021 5
CONFIDENTIAL 3 Total global vaccine production quadrupled within a year Vaccine production 2021, billion doses 20 Pipeline 5 Authorized in at least 1 geography 4x 10 5 Vaccines COVID-19 vaccines Total before COVID-19 Source: UNICEF COVID -19 production tracker with additional assumptions on realization and shipment timing of announced volumes (per vaccine development stage). Pre-COVID-19 vaccine data based on Airfinity and the WHO Global Vaccine Market Report 2020. DHL CSI – Customer Solutions & Innovation | Bonn | June 2021 6
CONFIDENTIAL 4 The complex global vaccine supply chain was ramped-up successfully DPDHL is the trusted partner for Covid-19 vaccine logistics worldwide Key contributions to date End-to-end Controlled >338 million doses distributed internationally All related solutions temperature products >140 countries served All approved vaccines Real-time >9,000 flights operated to deliver vaccines tracking >350 DHL facilities involved in the process All continents Highest security >50 collaborations in the pharma & public sector >10 new and dedicated services introduced DHL CSI – Customer Solutions & Innovation | Bonn | June 2021 7
CONFIDENTIAL 6 The vaccination rate already outpaces the infection rate by a factor of nine Covid-19 vaccination vs. cases Million people 700 People who have received 600 at least 1 dose 500 +550 since Jan 2021 400 300 200 Total COVID-19 cases 100 +65 since Jan 2021 0 Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May 2020 2021 Source: Our World in Data COVID-19 data explorer, Apr 28, 2021 DHL CSI – Customer Solutions & Innovation | Bonn | June 2021 8
CONFIDENTIAL Vaccine economics work: on a per capita basis end-to-end costs for 8 vaccination equal just one week of lockdown costs COST PER PERSON EUR ~300 - 500 E2E logistics represent ~3-8x
CONFIDENTIAL CHAPTER 2: It’s a marathon, not a sprint Out of the It’s a marathon, not a The home Getting ready for starting blocks sprint stretch the next race DHL CSI – Customer Solutions & Innovation | Bonn | June 2021 10
CONFIDENTIAL Only a small fraction of vaccination rollout achieved – upcoming phase will be challenging With 1 of 10 bn of the required doses … and the rollout to 220 countries pose administered, … … a concentrated production footprint challenges for logistics bn vaccine doses Number of countries clustered by the share of people fully vaccinated 10 >50% 4 95% of x10 global vaccine production is 10-50% 28 concentrated in 8 countries* 1 5% in the
CONFIDENTIAL 10 building blocks to go from 4 to 220 countries with successful vaccination campaigns 1 Partnerships without borders Fostering collaboration 2 Supportive data backbone Securing 3 Transportation capacity management inbound flows 4 Packaging sustainability 5 Strategic warehousing Setting up the last mile for 6 Synchronized flow of goods success 7 Vaccination points 8 Well-informed population Maximizing demand for 9 A User-Friendly Process vaccines 10 Incentives convincing last movers DHL CSI – Customer Solutions & Innovation | Bonn | June 2021 12
CONFIDENTIAL CHAPTER 3: The home stretch Out of the It’s a marathon, not a The home Getting ready for starting blocks sprint stretch the next race DHL CSI – Customer Solutions & Innovation | Bonn | June 2021 13
CONFIDENTIAL Going forward, 7-9 bn additional doses will be needed annually to keep COVID-19 in check Estimated additional vaccine quantities for 2022 and beyond The need for an additional 7-9 billion doses Billions will be driven by three factors: 4-5 billion doses will account for ”booster shots” to maintain the immunity of people who were Booster shots ~4-5 vaccinated in 2021. Patients in Another 2-3 billion doses will be earmarked for ~2-3 patient groups, such as children under the age of new groups 12, who will likely be eligible after the conclusion of ongoing clinical trials. New patients ~1 With time willingness to get vaccinated will likely increase, these new patients will account for an additional ~1 billion doses (assuming a 10- Total ~7-9 percentage point uptake). Source: UN Department of Economic and Social Affairs; Johns Hopkins Center for Communication Program; DHL analysis DHL CSI – Customer Solutions & Innovation | Bonn | June 2021 14
CONFIDENTIAL 3 watchouts needed to be implemented to ensure that today’s supply chain provides a solid platform for the next years Players need to implement 3 measures: … then supply chain provides solid platform due to 30% lower volume Projected global vaccine shipping volumes Remain prepared for high patient Billion doses and vaccine volumes ~15-20 ~12-14 ~12-14 Maintain logistics infrastructure and capacity ~10-15 ~7-9 ~7-9 5 Plan for seasonal fluctuations 2020 21 22 2023 Source: UNICEF COVID -19 production tracker, Airfinity and the WHO Global Vaccine Market Report 2020. DHL analysis DHL CSI – Customer Solutions & Innovation | Bonn | June 2021 15
CONFIDENTIAL CHAPTER 4: Getting ready for the next race Out of the It’s a marathon, not a The home Getting ready for starting blocks sprint stretch the next race DHL CSI – Customer Solutions & Innovation | Bonn | June 2021 16
CONFIDENTIAL Getting ready for the next race: 10 strategic actions governments and other stakeholders should consider pursuing now Prevention and early identification Containment and countermeasures Medication rollout capacity 1 Institutionalize active partnerships 5 Implement national containment and 8 Maintain “ever-warm” manufacturing and systems escalation plans capacity 2 Double down on global early-warning 6 Leverage digital contact tracing and 9 Define blueprint research, production, systems monitoring app and procurement plan for diagnostics, therapeutics, and vaccines 3 Create and follow through on 7 Establish an emergency stockpile and integrated epidemic-prevention associated “supplies and logistics” 10 Maintain and expand rollout agenda emergency system capabilities for diagnostics, therapeutics, and vaccines 4 Invest in targeted research and development to improve diagnostics, therapeutics, and vaccines DHL CSI – Customer Solutions & Innovation | Bonn | June 2021 17
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