Assessment & management of constipation in cats - Key Long term management - Feline ...
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2021‐04‐12 Assessment & management of constipation in cats Susan Little, DVM, DABVP (Feline) n Bytown Cat Hospital, Ottawa, ON, Canada @catvetsusan a catvet@vin.com u s 2 e t s a t v c @ Key assessments Long term management Effective acute treatment 6 1
2021‐04‐12 • Infrequent & difficult evacuation of feces with Constipation retention in colon & rectum • Acute & short term or chronic Terminology a n • Intractable constipation Megacolon • Poorly responsive to medical s therapy t s u e 7 a t v c @ Radiographic definition of megacolon Ratio of colon diameter to L5 length • Normal 1.5 8 2
2021‐04‐12 Functional definition of megacolon • Acute dilation that responds to therapy n • Chronically dilated colon, poorly a responsive s • Causes? • Recurrent constipation, obstipation u • Generalized dysfunction of colonic s smooth muscle 9 e t a t v c Colon motility patterns @ Propulsive Non‐propulsive • Rhythmic • Stimulated by segmentation that food & activity mixes contents • Absorption of water, electrolytes 10 3
2021‐04‐12 n The work up s a t s u e 12 a t v c Look for contributing factors @ Drugs Stress • Antacids Dehydration • Resource-poor • Opioids environment • Antidepressants • Intercat conflict • Diuretics • Underlying disease • Changes in routine • Opioids • Vomiting, diarrhea • Sucralfate • Impaired mobility, pain 13 4
2021‐04‐12 Chronic kidney disease • Dehydration • Hypokalemia • Reduced gastrointestinal n motility a • Phosphate binders s • Amlodipine t su e 14 a t v c @ 15 5
2021‐04‐12 Everyone’s favourite – the 01 enema De-pooping 02 Manual disimpaction – oh no! the cat a n s 03 There is a better way t s u e 16 a t v c Patient prep @ Correct dehydration Anti-emetic & hypokalemia Analgesic 17 6
2021‐04‐12 Manual disimpaction (why is it always when you’re ready to leave??) a n u s 20 e t s a t v c @ 22 8
2021‐04‐12 A better way! a n u s 23 e t s a t v c @ Laxative trickle-feeding Dr. Tony Carr Western College of Veterinary Medicine, University of Saskatchewan 24 9
2021‐04‐12 Colonoscopy or laxative solution intended for acute treatment Polyethylene glycol 3350 (macrogol) Sodium bicarbonate sodium chloride n potassium chloride a Brand names: s Golytely, Colyte, Movicol t s u e 25 a t v c @ 6‐10 mL/kg/hour 26 10
2021‐04‐12 Defecation in median 8 hours (range 6-14) Median total dose 80 mL/kg a n u s 27 e t s a t v c @ Pre-treatment 28 11
2021‐04‐12 8 hours later a n u s 29 e t s a t v c @ Everybody poops better at home! 30 12
2021‐04‐12 Pre-treatment a n u s t s Hannah Vds, Facebook Feline Veterinary Medicine Group e 31 a t v c @ Hannah Vds, Facebook Feline Veterinary Medicine Group 32 13
2021‐04‐12 a n s 7 hours later t s u Hannah Vds, Facebook Feline Veterinary Medicine Group e 33 a t v c Long term management @ Identify & manage concurrent diseases Hydration Dietary therapy Prokinetics, laxatives 35 14
2021‐04‐12 Hydration • Wet food • Flavoured water • Bottled/filtered water n • More water bowls • Subcutaneous fluids if appropriate s a t s u e 36 a t v c Dietary therapy @ Type of diet Low residue Increased fiber Characteristics Highly digestible Decreased fecal bulk Soluble & insoluble fiber: • Increased fecal bulk & water Examples • Hill’s Prescription Diet i/d Feline • Royal Canin Feline Gastrointestinal Fiber Response • Hill’s Prescription Diet w/d Feline or r/d Feline Soluble & insoluble fibre: • Increased fecal bulk & water Specific prebiotics: Modulation of • Hill’s Gastrointestinal Biome • Increased postbiotics that microbiome improve motility, provide energy, Digestive/Fiber Care anti-oxidant & anti- inflammatory effects 37 15
2021‐04‐12 When dietary therapy isn’t enough 01 Add a laxative 02 Add a drug n • Lactulose • Cisapride • PEG3350 (macrogol) • Metabolized in liver a without electrolytes by cytochrome P450 u s 38 e t s a t v c Top tips for managing constipated cats @ Identify Underlying factors, concurrent diseases Evaluate A D Provide Effective acute management Recommend Hydration, electrolytes B E Dietary therapy for long term management Radiograph Add GI obstruction, masses, pelvic C F Laxatives, drugs if needed fracture, colon size 39 16
2021‐04‐12 a n u s 40 e t s a t v c @ catvet@vin.com @catvetsusan @purrpodcast purrpodcast.net bit.ly/CatBites drsusanlittle.net 41 17
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