5th CIIT SCIENCE DAY June 26th, 2014

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5th CIIT SCIENCE DAY June 26th, 2014
th
5 CIIT SCIENCE DAY
     June 26th, 2014
5th CIIT SCIENCE DAY June 26th, 2014
Welcome                                                                     Remarks

To promote collaboration between science and teaching as well as to support diagnostics,
therapy and prevention of infectious diseases, the ´Comprehensive Center for Infection,
Immunity, and Transplantation (CIIT)´ was founded at the Innsbruck Medical University in
2009. The CIIT is co-ordinated by a speakers´ team from various disciplines and strengthens
the interdisciplinary exchange by organizing lectures of local and external speakers and
clinically oriented case studies (Grand Rounds).
A highlight in the CIIT event calendar is the CIIT Science Day. On June 26th, 2014, the 5th
CIIT Science Day will take place and again bring together allocated researchers with a
special focus on infection, immunity and transplantation. This day gives an overview of
current scientific topics and projects in respective research areas and on-going projects and
studies are presented by scientists during guided poster tours. This year 43 abstracts have
been submitted, which guarantees a broad scientific exchange and lively discussions.
Additionally, we are very glad that this year Prof. Quentin Sattentau from the Sir William
Dunn School of Pathology, Oxford University, will give the keynote lecture. The lecture is
entitled ´Immune Cell Contact in HIV Spread´ and will give an overview on T cells and
macrophages in the context of HIV infection and immunological and virological synapses.
Finally, we want to thank all people involved in the organization of this 5 th CIIT Science Day,
especially Susanne Rofner, Sonja Harm, the members of the CIIT speakers´ team and the
poster chairs. Furthermore, we want to acknowledge the Austrian Society of Allergology and
Immunology (ÖGAI) and the companies, which supported us financially. They are listed in
the back of the abstract book.
We wish all participants and guests an interesting and stimulating meeting and a lively
scientific exchange with possible future collaborations.

                                                   Doris Wilflingseder and Thomas Sonnweber
                                                           on behalf of the CIIT speakers´ team
5th CIIT SCIENCE DAY June 26th, 2014
Program

LOCATION: großer Hörsaal and Seminarräume MZA (Medizinzentrum Anichstraße
35)

Großer Hörsaal:
14.00-14.15         Introducing words: Univ.-Prof. Günter WEISS
                    Opening of the 5th CIIT SCIENCE DAY:
                    VRin Univ. Profin. Drin. Christine BANDTLOW

14.15-15.15         Keynote Lecture: Univ.-Prof. QUENTIN SATTENTAU
                    ´Immune Cell Contact in HIV Spread´

15.30-17.35         Moderated Postersessions (Seminarräume 1+2)

                                                   Postermoderator      Location
                                   Poster 1-11     Jakob Troppmair      SR1
15.30-16:30 Postersession I+II
                                                   Christine Heufler-
                                   Poster 12-22                         SR2
                                                   Tiefenthaler
                                   Poster 23-33    Ernst Werner         SR1
16.40-17.40 Postersession III+IV
                                   Poster 34-43    Hubertus Haas        SR2

Soft drinks and coffee will be available throughout the Poster sessions.

17.40-19.30 Posterdiscussions with light buffet and drinks
Abstract Index

Session   Nr.   Title                                          Presentator
                Phlebotomy in a Rat Model of
          1     Rheumatoid Arthritis reduces Systemic          A. Schroll
                Inflammation and Joint Destruction
                The Role of Jak2 in Hepcidin-dependent
          2     Ferroportin Internalisation in                 M. Aßhoff
                Macrophages
                Effects of Vasopressin on Migration and
          3     Oxygen Free Radical Release on                 M. Stichlberger
                Human Leukocytes
                Regulation of tumor-promoting iron
          4     turnover is accomplished by tumor-             P. Tymoszuk
                associated macrophages
                Langerin+ dendritic cells can initiate anti-
          5     tumor CD8+ T cell responses against            D.G. Mairhofer
                melanoma
I         6     The role of langerin-positive skin
                                                               D. Ortner
                dendritic cells in skin carcinogenesis
                Immunological Aspects of Iron Overload
          7                                                    T. Resch
                in Solid Organ Transplantation (SOT)
                Critical Ischemia Time and the Effect of
          8     Preservation Solutions on I/R Injury in a      F. Messner
                Rat Hind-Limb Transplantation Model
                Alkylglycerol monooxygenase in
          9                                                    S. Sailer
                Adipocyte Differentiation
                A New Biomarker Panel And Diagnostic
                Accuracy In Female Patients With
          10                                                   A Kronbichler
                ANCA-associated Vasculitis (DIVA) – A
                Pilot Study
                Donor Brain Death Does Not Aggravate
          11    The Ischemia/ Reperfusion Injury In A          P. Ritschl
                Murine Kidney Transplantation Model
                Interaction between EHEC and innate
          12                                                   I. Arbesú Cruz
                immunity under gut condition
                Heat Shock Protein 70 family members
          13    participate in Amphotericin B resistance       M. Blatzer
                of Aspergillus terreus
                Complement opsonization of HIV-1               W. Posch
          14    beats SAMHD1 restriction in dendritic
                cells
                Dendritic cell infection by complement-
          15    opsonized HIV is associated with an            M. Steger
                aberrant type I IFN response
II        16    Siderophore       Utilization   determines
                                                               L. Schafferer
                Fungal Competitiveness
                DC-oding        signaling      mechanisms
          17                                                   U.Knackmuss
                dependent on the viral make-up
                HIV-1 Gene Therapy Using Zinc Finger
          18                                                   K. Schmidt
                Nucleases (ZFN)
                PKC Controls IL-10 Secretion in
                Macrophages during Protective Immunity
          19    against     Infection    with   Salmonella
                                                               C. Pfeifhofer-Obermair
                Enterica Serovar Typhimurium
                Regulation of Iron Homeostasis and
          20                                                   D. Haschka
                Immune Function in Murine
Macrophages Infected with Listeria
           monocytogenes
           Lipocalin-2 Links the Maintenance of
           Iron Homeostasis to an Efficient Immune
      21   Response           against       Salmonella
                                                            M. Nairz
           typhimurium
           Bactericidal Activity of N-chlorotaurine
      22   against Chlamydia pneumoniae
                                                            R. Bellmann-Weiler
           Human skin dendritic cells can be
           targeted in situ by intradermal
      23                                                    S. Schaffenrath
           injection of antibodies against lectin
           receptors
           LCMV-GP          Pseudotyped        Oncolytic
      24   Vesicular Stomatitis Virus for the               C.R. Urbiola
           Treatment of Prostate Cancer
           Role of Mitogen-activated Protein
           Kinases (MAPKs) and PKC in the
      25   Activation of p66SHC: A Novel Approach           S. Khalid
           for the Prevention of ischemia/
           reperfusion Injury (IRI)?
           Heme oxygenase-1 gene promoter
           microsatellite        polymorphism          is
      26   associated           with        progressive     R Pechlaner
           atherosclerosis           and         incident
           cardiovascular disease
           The Viral Vector Vaccine VSV-GP
      27   Boosts the Immune Response upon                  J. Kimpel
III        Repeated Applications
           HFE Deficiency Critically Affects
      28                                                    E. Demetz
           Cholesterol Homeostasis in Mice
           The Arachidonic Acid Metabolome as
      29   Conserved Regulator of Cholesterol               E. Demetz
           Metabolism
           Pediatric Liver Transplantation: An
      30   Outcome Analysis of a 30-Year                    A. Weißenbacher
           Experience in a Single Center
           Hand Transplantation at Innsbruck
      31   Medical University – The Clinical                A. Weißenbacher
           Experience after the Fifth Patient
           Hypoxia induced downregulation of
      32   hepcidin is mediated by platelet derived         T. Sonnweber
           growth factor BB
           Bone marrow T cells from the femur are
           similar to iliac crest derived cells in old
      33                                                    T. Pritz
           age and represent a useful tool for
           studying the aged immune system
           In vitro activity of amphotericin B and
      34   posaconazole against common agents of            R. Caramalho
           mucormycosis.
           Influence of hypoxia on antifungal
      35   susceptibility, sterol pattern and               E. Maurer
           biomarker release of Aspergillus spp.
           The homologous Lipocalins dog Can f 1
IV    36   and human Lcn-1 direct Dendritic Cells           B. Posch
           to induce divergent Immune Responses
           corresponding to their Allergenicity
           In vitro effects of Ag and Al2O3
      37   nanoparticles on human peripheral blood          K. Becker
           mononuclear cells
           Neonatal Urinary Ascites due to
      38                                                    B. Brunner
           intrauterine fetal Bladder Rupture
associated with severe maternal H1N1
     Influenza Infection at 28 weeks of
     gestation – Case Report
     The Role of Heme Oxygenase 1 in
     Regulating Iron Homeostasis and Innate
39   Immune Response to Salmonella
                                                  A.-M. Mitterstiller
     Infection
     Targeting mitochondrial respiratory chain
     and       redox     status     potentiates
40                                                E. Jukic
     Amphotericin B-mediated antifungal
     activity
     Ergothioneine is involved in antioxidative
41   Defense in Aspergillus fumigatus
                                                  B. Lechner
     Specific Cell Wall Compounds of
42   Aspergillus fumigatus Conidia and            G. Rambach
     Hyphae Modulate Platelet Activity
     Breath Analysis for In Vivo Detection of
     Pathogens Associated with Ventilator-
43                                                W. Filipiak
     Associated Pneumonia in Neurocritical
     Care Patients: A Prospective Pilot Study
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