The Swiss Cosmetics and Perfume Industry

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The Swiss Cosmetics and Perfume Industry
The Swiss
                        Cosmetics and Perfume Industry
                        By Maria Lüder*

                        SWISS SCC 29th Winter Seminar Champfèr 2011                                                           (Part II)

   The second part of the seminar is starting                                                        quirements as the ISO 22716 standard Cos-
with the Tuesday afternoon’s session. Pri-                                                           metic GMP. The centerpiece of IFS Stand-
vate label manufacturer and their options to                                                         ards is the risk analysis to protect the con-
differentiate in a highly competitive market                                                         sumers which are used in all processes.
started the session. Later in the afternoon                                                          CWK-SCS has developed an innovative eval-
new carrier systems and their delivery                                                               uation table for the risk analysis. This ena-
principles were presented. The newest de-                                                            bles the classification and assignment of
velopments in UVA-protection rounded the                                                             risks according to the dangers, the potential
lectures of this afternoon.                                                                          gravity in case of accident and the feasibility
                                                                                                     of happening. All relevant processes are
                                                                                                     judged by the danger and risk analysis team
Differentiation as private label manufac-
                                                                                                     according to the evaluation table und sum-
turer, thanks to IFS-HPC-Standards
                                                                                                     marized in a risk matrix. Monitoring of the
Dr. Beat Müller – CWK
                                                      Dr. Beat Müller, CWK                           critical points in the processes is in-build
   CWK-SCS, a Division of Coop is world-                                                             into so called CPs (Control Points).
wide the first company, certified for the             About 190 Retailer use the standard as qual-
new IFS-HPC Standard. Die Abbreviation                ity insurance tool for their private labels.      The IFS HPC Standard could be intro-
IFS-HPC is standing for “International Fea-                                                          duced and audited in CWK-SCS within only
tured Standard Household and Personal                    The IFS HPC Standard contains 224 con-      6 months. This challenging time line was
Care”. The new standard for Non-Food                  trol points in the areas of company respon-    only possible due to the internally existing
Products developed from the much better               sibility, quality management, resource man-    know-how around the IFS Food Standard.
known IFS (Food) Standard, which was in-              agement, production processes, quality         From CWK-SCS point of view the IFS HPC
troduced 2003 and reached a benchmark                 control and continuous improvement. The        Standard improves the product safety and it
status in 90 countries with 12’000 certified          standard goes much beyond legislation and      is a tool to build trust and reputation to-
companies for HACCP risk management.                  is much more concrete regarding the re-        wards the customer.

* SWISS SCC - Public Relation, m.lueder@swissscc.ch

                                                                     5-2011   32   EURO COSMETICS
The Swiss Cosmetics and Perfume Industry
Differentiation as private label producer,                                                                        Therewith an international marketing is
thanks to ECOCERT Formulations                                                                                    possible. For the developer an Ecocert certi-
Judith Fiedler – CWK                                                                                              fication offers enough flexibility and there-
                                                                                                                  with the possibility to develop user-friendly
   In the area of international private label                                                                     products. The product requirements are
business retailers are working with auc-                                                                          clearly regulated for natural and organic
tions, to find the cheapest supplier for a                                                                        natural cosmetics, raw material data are
specific product. Quality differences are                                                                         available online, calculations are easy to re-
only recognized for the product evaluation                                                                        alize with given examples. Ecocert is further
after the first price indications. Here, the                                                                      exhibiting the subject of packaging, design
natural cosmetic market offers an alterna-                                                                        and cleaning rules into the evaluation and
tive. There are few suppliers, following that                                                                     reviews the production annually. Thanks to
the market is not yet that strongly deter-                                                                        the design standards every user can com-
mined by the price. The past niche market                                                                         prehend the certification criteria at every
develops into a strong standing leg in the                                                                        time.
cosmetic segment. Reachable prices and                                                                               Ecocert certified natural cosmetic offers
margins for the products are higher by the              Judith Fiedler, CWK                                       the international private label manufacturer
additional benefit of “sustainability”. This                                                                      a differentiation towards the market and in-
increases the attractiveness of the market              Ecocert is a pioneer in the area of bio ingre-            ternational distribution possibilities are of-
for manufacturers and retailer. A label offers          dients and natural cosmetic. The Ecocert                  fered even outside the German speaking
the retailer the necessary safety and clarity.          label has an international propagation.                   area.

      «SILAB actives
      «SILAB  actives
      you can’t
      En
          can’t perform
                 performwithout»
      En complément
         complément de
                         without»
                    de ses
                       ses actifs
                            actifs « Innovation »,
                                   « Innovation », SILAB
                                                   SILAB propose
                                                         propose une
                                                                 une nouvelle
                                                                     nouvelle gamme
                                                                              gamme d’actifs
                                                                                    d’actifs « les incon-
                                                                                             « les incon-
      tournables SILAB
      tournables SILAB »
                       » ::

      Complementary
      Complementary
      Actifs
      Actifs         «Innovation»
                     «Innovation»
                            to the
                            to
             d’origine naturelle
             d’origine naturellethe
                                 objectivés grâce
                                 objectivés grâce à
                                                  à des
                                                    des études range,
                                                         étudesrange,
                                                                in-vitro SILAB
                                                                in-vitro SILAB
                                                                         et in-vivo
                                                                         et        proposes
                                                                            in-vivoproposes
                                                                                    « les
                                                                                    «           a new
                                                                                                a new range
                                                                                                        range
                                                                                      les incontournables
                                                                                          incontournables      of active
                                                                                                          SILABof
                                                                                                          SILAB   active substances
                                                                                                                         substances called
                                                                                                                                     called
      «SILAB actives
      «SILAB
      »      actives you
      » s’imposent    you can’t
        s’imposent comme  can’t perform
                                perform without»
                     comme ingrédients  without»
                             ingrédients essentiels
                                         essentiels de
                                                    de la
                                                       la cosmétique
                                                          cosmétique dede soin.
                                                                           soin.              that
                                                                                              that are
                                                                                                    are essential
                                                                                                         essential ingredients
                                                                                                                   ingredients in cosmetic
                                                                                                                               in cosmetic
      skincare products.
      skincare products.
      L’ingrédient de
      L’ingrédient    de performance
                          performance :: ilil apporte
                                              apporte l’efficacité
                                                      l’efficacité ciblée
                                                                   ciblée et
                                                                          et absolue
                                                                             absolue au au problème
                                                                                            problème cutané.
                                                                                                        cutané. Sélection-
                                                                                                                Sélection-
      né  in-vitro sur
      né in-vitro  sur un
                       un marqueur
                          marqueur biologique
                                   biologique spécifique
                                                 spécifique fortement
                                                              fortement stimulé,
                                                                         stimulé, ilil est
                                                                                       est validé in-vivo en
                                                                                           validé in-vivo en comparaison
                                                                                                             comparaison                            S ILAB
                                                                                                                                                ess S
                                                                                                                                           a bl
      à des
      à des molécules
              molécules pharmacologiques
                          pharmacologiques de   de référence
                                                   référence (Rétinol,
                                                               (Rétinol, peptides
                                                                         peptides de de synthèse,
                                                                                         synthèse, caféine…).
                                                                                                     caféine…).                        u rn
                                                                                                                                      o
            The high-performance
            The high-performance ingredient
                                 ingredient
                                                                                                                                 nt
                                                                                                                               co

                                                                                                                                                                    m without

      L’actifProvides
              multifonction
            Provides        :: ilil garantit
                      targeted      garantit l’homéostasie
                                     and absolute
                                         absolute             cutanée to
                                                       effectiveness    et the
                                                                       to   assure
                                                                           the      une efficacité
                                                                               problem   efficacité
                                                                                          of skin. vitale sur
                                                                                             skin. vitale sur différents
                                                                                                              différents
                                                                                                                        Less in

      L’actif multifonction
                      targeted       and     l’homéostasie    cutanée
                                                       effectiveness    et  assure  une
                                                                               problem    of
      compartiments. Capable
      compartiments.  Capable de    de réguler
                                       réguler différentes
                                                 différentes voies
                                                              voies biologiques,
                                                                    biologiques, ilil apporte
                                                                                      apporte des
                                                                                              des réponses
                                                                                                   réponses multiples
                                                                                                              multiples
      aux déséquilibres
      aux déséquilibres cutanés.
                        cutanés.
            The multi-function
            The multi-function active
                               active principle
                                      principle
                                                                                                                                                                for

      Assurant
      Assurant une veille
           Restores
               une
           Restores veille
                       skinscientifique
                       skinscientifique
                             homeostasis
                             homeostasiscontinue,
                                        continue,
                                             and  disposantvital
                                             and disposant
                                                  ensures
                                                  ensures    d’équipements
                                                             vital            high-tech
                                                                   effectiveness
                                                             d’équipements
                                                                   effectiveness        et de
                                                                                           de chercheurs
                                                                                              chercheurs
                                                                                   on different
                                                                                   on different
                                                                              high-tech et                 haute-
                                                                                                 layers. haute-
                                                                                                layers.
                                                                                                                                                                r
                                                                                                                                                             pe

                                                                                                                                  IL                       't
      ment qualifiés,
           qualifiés, SILAB,
                      SILAB, grâce
                              grâce à à ses
                                        ses principes
                                            principes actifs
                                                      actifs «
                                                             « Les
                                                                Les incontournables
                                                                     incontournables SILAB
                                                                                     SILAB » » et
                                                                                               et «
                                                                                                  « Innovation
                                                                                                    Innovation »,»,
                                                                                                                               S

      ment                                                                                                                           AB                  an
                                                                                                                                           act ives   u c
      répond aux
      répond aux attentes
                  attentes du
                            du marché
                               marché cosmétique
                                         cosmétique mondial
                                                     mondial à à la
                                                                 la recherche
                                                                    recherche de
                                                                               de toujours
                                                                                  toujours plus
                                                                                           plus d’efficacité
                                                                                                d’efficacité et
                                                                                                             et de
                                                                                                                de                                s yo
      nouveautés.
      nouveautés.
                In-cosmetics: Visit us on our booth n°Q40

     SILAB -- BP
     SILAB    BP 213
                  213 -- 19108
                         19108 Brive
                               Brive CEDEX
                                     CEDEX -- France      silab@silab.fr -- www.silab.fr
                                                France -- silab@silab.fr    www.silab.fr
     Its subsidiaries
     Its subsidiaries and
                      and aa worldwide distribution network
                             worldwide distribution network

                                                                      5-2011    33       EURO COSMETICS
The Swiss Cosmetics and Perfume Industry
Glycospheres®                                       other described spheres, not only spherical
                                                           Glycospheres® have a solid center formed         but over and over streaked by a network of
                                                        of modified starch. The external layer              liquid crystalline membranes. Encapsulated
                                                        around the center, a lipid membrane is build        substances can like this be released in a
                                                        of fatty acids and polar lipids, thus the whole     controlled way. By the degree of the net-
                                                        vesicle is made of natural raw materials. The       work the rate of release can be adjusted.
                                                        hydrophilic actives (especially anionic sub-        The SPF of sun care formulations can be
                                                        stances) are imbedded into the positively           improved by the use of these particles.
                                                        charged cellulose polymers and are there-
                                                        fore well protected against external influ-         UltraSpheresTM
                                                        ences like heat and oxidation. The vesicles            UltraSpheresTM are forming a nanoemul-
                                                        of 200nm are not able to penetrate due to           sion with phosphatidylcholine as natural
                                                        the rigid internal center and they can release      emulsifier. The encapsulation of hydropho-
                                                        the actives under increased ion contents.           bic actives in the single, flexible membrane
                                                                                                            of the UltraSpheresTM will increase the bio-
                                                        Sophi-Hydro-Spheres                                 availability of actives in skin. UltraSpheresTM
                                                           Sophi-Hydro-Spheres form a new innova-           release the actives sustainably over a time
Dr. Gabriele Blume, Sopharcos                           tive carrier system which has similar and           frame of several hours (Slow Release).
                                                        better properties than the long known lipo-
Small Actives carriers – very big, spherically          some. Sophi-Hydro-Spheres consist of a              Sophi-Lipo-Spheres
well into skin                                          membrane forming anionic, eatable emulsi-              Sophi-Lipo-Spheres are mainly consisting
Dr. Gabriele Blume – Sopharcos                          fier that is similar in structure to phosphati-     of membrane forming anionic, eatable
                                                        dylcholine. The emulsifier is also a diglycer-      emulsifiers like the Sophi-Hydro-Spheres
  Carrier systems have an importance in                 ide and esterified with 2 long chain fatty          and must also be stabilized with a co-emul-
the cosmetic industry for a long time al-               acids (linoleic acid and oleic acid). Both fatty    sifier. The colloidal carrier system has an
ready. At the end of the 1980’s Capture of              acids are from sun flowers and therefore            average vesicle size between 100 -180 nm
Christian Dior used a liposome for the first            non-GMO. As head group the salt of a car-           and in the center lipophilic substances are
time. It is still being used in Capture Com-            bon acid is used (lactic acid and citric acid),     encapsulated in high concentrations (20 -
plex Liposomes Smoothness Radiance Firm-                giving the vesicle a negative surface charge.       40%). The encapsulated actives can be sta-
ness. New innovative carrier systems                    For stabilization of the vesicle a further ac-      bilized in formulations significantly. The
„Spheres“ (welkin) have been introduced                 tive respectively an emollient is used. Hy-         penetration of the encapsulated lipophilic
recently to the cosmetics business.                     drophilic and amphiphilic actives can be            substances (lipophilic vitamins) into the
                                                        encapsulated. In comparison to liposomes            skin could be demonstrated by ESR (Elec-
   Such carrier systems are often used to               the spheres have an advantage regarding             tron Spin Resonance Spectroscopy).
stabilize the most very expensive active in-            the encapsulation efficiency of amphiphilic
gredients and/or work as transport system               substances and salts of acids. The penetra-         Literature:
to carry the active ingredients to the in-              tion properties of liposomes and spheres            Glycospheres®:
tended skin layer. Nowadays systems can                 are comparable, the high stability of the             Kobo Products Incorporated, USA
even be used to prevent penetration of ac-              new vesicles in cosmetic formulations was           Kem-SpheresTM:
tive ingredients, by forming a depot on the             demonstrated to be superior.                          Sachtleben Chemie GmbH, Duisburg
skin’s surface.                                                                                             UltraSpheres®:
                                                        Kem-Spheres®                                          ROVI Cosmetics International GmbH,
  The following table is a summary of cho-                Kem-Spheres® consist mostly of waxes                Schlüchtern
sen carrier systems, presented in detail:               and emulsifiers and are, opposite to the

 Carrier system            Material                      Actives                          Size              News about the in vitro determination of
                                                                                                            the SPF of sun screen agents,
 GlycoSpheres®             Lecithin + modified Starch    hydrophobic + hydrophilic        200 nm
                                                                                                            Prof. Dr. Ulrike Heinrich – Dermatronnier
 Sophi-Hydro-Spheres       Emulsifier + Emollient        hydrophilic                      80–300 nm
                                                                                                              Since many years there is an interest in a
 Kem-Spheres®              Waxes + Emulsifiers           hydrophobic                      50–500 nm         validated in-vitro measurement of the SPF.
 UltraSpheresTM            Lecithin + Oil                ydrophobic                       100–300 nm        On the one hand there are ethical aspects,
 Sophi-Lipo-Spheres        Emulsifier + Co-emulsifier    hydrophobic                      100–200 nm
                                                                                                            to not expose volunteers to irradiation with
                                                                                                            UV-light, on the other hand a less costly and

                                                                       5-2011        34    EURO COSMETICS
The Swiss Cosmetics and Perfume Industry
ternational „Ad hoc Advisory Group“ was
                                                           founded, formed of member states from Ja-
                                                           pan, USA, England, The Netherlands, France
                                                           and Germany. The evaluation of all appro-
                                                           priate examination conditions and work on
                                                           proposals for an optimized study procedure
                                                           was the task. At the moment many ideas
                                                           have been collected that will be presented
                                                           to the ISO next spring. Based on improving
                                                           framework conditions of in vitro determina-
                                                           tions of sun screens an international exami-
                                                           nation protocol might be presented in fu-
                                                           ture enabling a valid, fast and economic           Rene Grüter, CTS-Group
                                                           SPF-determination.
                                                                                                              Sustainable Market Success – Success Factor
                                                           Literature:                                        Human Being
                                                           [1] In vitro SPF: still a challenge with no fi-    René Grüter - CTS Group
Prof. Dr. Ulrike Heinrich, Dermatronnier                       nal answer. Rohr M, Klette E, Ruppert S,
                                                               Bimczok R, Pflücker F, Klebon B, Hein-            Between the poles of short term eco-
                                                               rich U, Tronnier H, Johncock W, Peters         nomic success, Share/Stakeholder expecta-
more efficient test procedure would be ap-                     S, Rudolph T, Flösser-Müller H, Jenni K,       tions and an always faster moving market
preciated.                                                     Kockott D, Lademann J, Herzog B,               dynamic, to give space to entrepreneurial
                                                               Bielfeldt S, Mendrok-Edinger C, Hanay          visions, taking the factor “human being”
   The DGK professional group „sun protec-                     C, Zastrow L.; Skin Pharmacol Physiol          into account, is an enormous challenge.
tion“ has worked with the help of ring stud-                   2010; 23:201-212                               Sustainable successful entrepreneurs but
ies to develop a validated procedure for the                                                                  also entrepreneurial thinking managers
SPF-measurement. Different substrates with                    The Wednesday morning was determined            recognize die necessity of the investment in
defined roughness were examined with the                   to human resources on the one hand and to          the development from the „Company-Fac-
aim to simulate the skin surface. Addition-                biodiversity on the other hand under the           tors“ to the „Success-Factor Men”.
ally other parameters like different sizes of              slogans Success Factor Human Being and                To organize the whole HR-process in a
film thickness per product sample were                     Biodiversity.                                      company successfully, it applies to actively
taken into account. The many very different
galenic forms of sun screens (Spray, Lotion,
Cream or Stick) were a challenge to over-
come and finally also the natural irradiation
und measuring conditions play a substantial
role.
                                                                                                                                                         info@frankenchemie.de

   The aim of all methodological standards
                                                  www.frankenchemie.de

was to reach a good correlation to the in
vivo SPF-determinations, whereby it is
                                                                                                       i e l falt
                                                                                                     v
                                                                                                 toffiduell inden
known that even those underlie a certain
scatter. In common trainings (User-Meet-                                                     h s
                                                                                        Ro ndiv ngeb
ings) a relative good correlation of the labo-
                                                                                              I      lei
ratories could finally be reached. Neverthe-                                                       K
less the problem remained that inside one
                                                                                         u c h in
laboratory better results could be obtained                                            A
than between different laboratories. Also
on an international level corresponding ring
studies e.g. ISO had similar results. Due to
the enormous interest of the industry and
additionally of the authorities, a special ini-
                                                                                        Richtweg 81 · D-90530 Wendelstein
tiative of the ISO took place last year. An in-
                                                                         Tel.: +49 (0) 91 29 / 28 18 - 0 · Fax: +49 (0) 91 29 / 28 18 - 30

                                                                              5-2011    35   EURO COSMETICS
The Swiss Cosmetics and Perfume Industry
support it from the hiring process to the           The development of single employees and
evaluation and development up to the resig-      teams could be supported by the tool of a
nation. Beside the „hard skills“, that can of-   „Development-Roadmap“ with the slogan
ten be measured directly and can be com-         „forward thinking, backward understand-
pared with more or less standardized meth-       ing“ which can create valuable benefits. All
ods, a high priority must also be allocated to   you need is openness, sense of reality and a
the „soft skills“ – the attitude oriented fac-   professional moderation to guarantee the
tors. Because these mainly determine the         disclosure of possible blind spots that could
company culture and therefore joy & sym-         become problems.
pathy which show the employees as mirror
of the company externally and could create          Predictive, proactive „best placement“
the decisive advantage at customers and in-      leads to the development of idle potentials
vestors.                                         in an organization that again recuperates
                                                 the customers, the company and the em-
  For a sustainable contribution to the com-     ployees (e.g. new perspectives).
pany success the development of groups to
performing teams is inevitable.                     The „best placement“ process could also
                                                 lead to the conclusion that a separation
   Already during the recruiting of an em-       forms the best solution. In this case all in-
ployee bottom line happens. This is the          volved people is best helped to make defini-    Bela Bartha, ProSpecieRara
time where the superior mandatorily should       tive decisions and shape the separation
think of which behavior-oriented ideal pro-      process fair and future oriented e.g. with      managed to make up its mind signing a bio-
file is needed to complement the group or        the support of a professional outplacement.     diversity convention in Rio that has the aim
the team. One has to scrutinize the areas of                                                     to keep the whole versatility of creatures on
personality that are important for the suc-      Conclusion                                      earth. One of the signing states was Switzer-
cess or the fail of a working relationship         That the human being is a success factor      land, that 1998 based on the global action
from a sociological and psychological point      for market success in a company is undis-       plan developed a national action plan (NAP)
of view:                                         puted. To develop existing potential and to     and since then gives money for the realiza-
          Thinking structures, attitude,         market it requires a conscious focus to the     tion.
      mindset, social- and daily behavior        HR-process along the whole development
                                                 chain. This lies in the first instance in the     ProSpecieRara tries to contact economic
  Next to this „holistic“ approach it is rec-    responsibility of the executives and may not    partners who can use the genetic resources
ommended to focus early on a leadership          be delegated to the personnel department.       for its products and therefore can take hold
recognition during the HR-process. With                                                          of the offered reservoir, directly or indi-
the help of psychometric tests – it is recom-                                                    rectly. Together with these partners strate-
                                                 Biodiversity in Switzerland,
mended to use practice oriented, simple                                                          gies are developed how the further develop-
                                                 Béla Bartha - ProSpecieRara
and easy understandable tools – well fitting,                                                    ment and use of the resources knowledge
complementary additions to existing teams          1982 the Swiss foundation ProSpecieRara       could be obtained and a percentage of the
can be assured.                                  was established with the aim, to keep and       sales again is used for maintenance work.
                                                 promote the versatility of agriculturally
   Specifically in markets where innovation      used animals and plants. Ever since an            Mibelle Biochemistry and ProSpecieRara
and marketing are the driving force of suc-      amazing versatility in this collection could    have found an exemplary way, how such
cessful business models – like e.g. in the       be saved, spread over the whole of Switzer-     collaboration between a private company
cosmetic industry – questions for the best       land. How the foundation came to 1800           that likes to make use of the collection and
possible mix of specialists and generalists as   fruits, 450 berries and over 1000 vegetables,   an organization that delivers it with its net-
well as the ability to communicate with each     as well as 200 ornamental plants and with       work could look like.
other in parallel functions effectively and      which methods the foundation gets it is the
efficient (Interface-management, e.g. F&E /      topic of the first remarks.                       Wednesday afternoon first had social
Sales & Marketing) have priority. Likewise                                                       components in the program with Corporate
actual (textbook)-knowledge should be              What the foundation did in the first years    Social Responsibility. The second part was
combined with lived front experience, re-        was typical pioneers work, because it           the science around Screening Tests at Plant
spectively building a fruitful mix which is      should take one decade until the official in-   Extracts and Efficacy Tests with Cell Cul-
the basis for high performance teams.            ternational community of states finally         tures.

                                                              5-2011   36       EURO COSMETICS
The Swiss Cosmetics and Perfume Industry
Corporate Social Responsibility,                                                                           at. Offers of healthy food for employees,
           Dr. Andrea Weber - Dr. Babor GmbH & CO. KG                                                                 over restoration of historical facades in
                                                                                                                      Aachen up to energetic measures were pre-
              According to the definition of the Euro-                                                                sented.
           pean Commission CSR (Corporate Social
           Responsibility) is a concept, where compa-                                                                   The company Dr. BABOR has incorporat-
           nies voluntarily social and also environmen-                                                               ed the subject sustainability with all its fac-
           tal subjects can implement into companies                                                                  ets included in future subjects.
           activities and therewith contribute to the
           global sustainability and competitiveness.
                                                                                                                      Screening Tests at Plant extracts
                                                                                                                      Dr. Evelyn Wolfram - ZHAW Wädenswil
             Many of the multinational companies
           demonstrate their activities to take on cor-                                                               Requirements of the
           porative responsibility on different internet                                                              cosmetic industry to plant extracts
           platforms. The listed action plans let the                                                                   Cosmetic products contain more and
           question come up whether also SME’s                                                                        more plant extracts that should support the
           (smaller to medium size enterprises) could                                                                 products with a label claim or as active in-
           change business activities in the sense of                                                                 gredients for strong efficacy claims or a
           social and environmental acting?                                                                           combination of both. Following an estimate
                                                                                                                      more than 1000 different plants and parts of
             In the seminar activities and measures of                                                                plants are used for cosmetic purposes, a
           Dr. BABOR with respect to CSR were looked        Dr. Andrea Weber, Dr. BABOR GmbH & Co. KG                 further expansion not excluded.
Personal Care Anz_A5 quer Pf 25.11.2009 15:30 Uhr Seite 1
                                                                                         C   M   Y      CM   MY   CY CMY   K
The Swiss Cosmetics and Perfume Industry
hibiting properties can be examined with
                                                 the focus of High Performance Liquid Chro-
                                                 matography (HPTLC).

                                                 Efficacy Tests with Cell Cultures
                                                 Dr. Margret Ebauer – CELLnTEC Advanced
                                                 Cell Systems
                                                   The cosmetic industry has developed a
                                                 wealth of new active ingredients in the last
                                                 decades that should make us younger, more
                                                 beautiful and should let us look more radi-
                                                 ant. Advertising messages of the industry
                                                 are not always supported by independent
                                                 scientifically based tests.

                                                   Efficacy tests, above all the progress in
                                                 cell biology with the possibilities of cell
                                                 cultures and new effective analysis methods      Dr. Margret Ebauer, CELLnTEC AG
                                                 advanced enormously. Visualized effects of
Dr. Evelyn Wolfram, ZHAW-Wädenswil               an active ingredient could be coupled with       stem cells have been identified as promising
                                                 the corresponding working mechanism.             approaches for anti aging applications.
Screening of Plant Extracts:
Quality- and Efficacy Examinations               New in-vitro Models                                 Over the last years conventional tests to
  The cosmetic legislation oblige manufac-          The today conventional handling of in         identify the working mechanism have been
turers to present a certificate of their prod-   vitro cell culture comprises the so called       complemented with new methods that al-
ucts efficacy if an effect is claimed. In the    2-dimensional (2D) cell cultures. Indeed the     low the analysis of dozens up to thousands
past literature research delivered hints for     2D-cultures can be very sensible for the ex-     of characteristics at the same time. One can
corresponding tests of a possible plant ef-      amination of a specific questioning, howev-      speak about multiplex approaches. On the
fect.                                            er remain a very simplified model of the         one hand a huge number of active ingredi-
                                                 complex in vivo situation because many           ents can be screened at the same time on
   An identical INCI denomination of a           physiological processes cannot be dis-           the other hand their effects can be exam-
number of extracts cannot describe suffi-        played.                                          ined for different biological signaling path-
ciently enough the effective substantial                                                          ways.
composition of multi component mixtures.            3-dimensional (3D) cell cultures, being
The contents can vary substantially. The         very similar to the physiological scaffold,         The scientific part of the Winter Seminar
used plant parts play a big role next to the     were developed. The epidermal 3D skin            ended here. On Thursday afternoon 2
year’s harvest and the origin of the plant       model consist of different layers with prolif-   compnaies presented a number of interest-
material, as well as the kind, the duration of   erating cells in the basal layer und mature      ing cosmetic ingredients. Michéle Lindner
the extraction, the solvent, the concentra-      cells in the upper layer what corresponds to     together with Brigitte aus dem Siepen GFN-
tion of plant material in solvent, tempera-      the natural tructure of skin. Hence is the       Selco GmbH presented interesting active
ture and solid-liquid separation and eventu-     reaction to different factors in 3D structures   ingredients followed by Dr. Joachim Blank,
ally further preparations steps.                 very similar to normal skin. Some processes      Brenntag Schweizerhall AG who introduced
                                                 specifically the regeneration and differentia-   “green” emulsifiers to the audience. Birgit
   Instruments are needed that can show          tion processes can be examined much more         Hämel, S&D Chesham GmbH asked a philo-
the optimization or the reduction of extract     precise and a possible in vivo reaction can      sophical question Who is the human being?
efficacy depending of the used process pa-       be predicted.                                    At the end of this article it is time for the
rameters.                                                                                         first outlook to the next year’s event. The
                                                 New in-vitro Methods                             Winter Seminar 2012 takes place from Janu-
  In the lecture examples of tools to detect       With the new in vitro methods the culti-       ary 29 – February 3. The subject of the
different parameters for plant extract           vation of stem cells and precursor cells is      coming Winter Seminars is:
screenings are presented. Phytochemical,         one of the most important developments.
antioxidative, antimicrobial and enzyme-in-      Protection and regeneration of epidermal                „(no) Limits in Cosmetics“

                                                               5-2011   38     EURO COSMETICS
The Swiss Cosmetics and Perfume Industry The Swiss Cosmetics and Perfume Industry The Swiss Cosmetics and Perfume Industry
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