The 2021 Fresco International Workshop on Synaptic Plasticity and Advances in Parkinson's Disease
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NYU Grossman School of Medicine Continuing Medical Education The 2021 Fresco International Workshop on Synaptic Plasticity and Advances in Parkinson’s Disease Tuesday–Friday, October 12–15, 2021 Florence, Italy nyulmc.org/frescocme Endorsed by the International Parkinson and Movement Disorder Society, the Parkinson’s Foundation, the LIMPE-DISMOV Academy, the Italian Society for Neuroscience, the Societa Italiana di Neurofisiologia Clinica, and the Societa Italiana di Psicofisiologia e Neuroscienze Cognitive
The 2021 Fresco International Workshop on Synaptic Plasticity and Advances in Parkinson’s Disease WORKSHOP DIRECTORS other health care professionals working with patients with Parkinson’s disease and related disorders as well Angelo Quartarone, MD as neuropsychiatric disorders M. Felice Ghilardi, MD Mark Hallett, MD Monica Norcini, PharmD, PhD MEETING APP Meeting materials will be distributed electronically via COURSE DIRECTORS an app. Emails regarding the app will be sent beginning Andrew S. Feigin, MD two weeks prior to the meeting. You will be able to Steven J. Frucht, MD download the app and view the meeting materials in Un Kang, MD advance, as well as on the day of the meeting. The app Monica Norcini, PharmD, PhD can also be viewed on a desktop or laptop. The meeting presentations will be available for view/download/print MEETING DESCRIPTION the week of the meeting. The meeting app will remain Join us in Florence, Italy for the Fresco meeting available for one year after the meeting. this October focusing on synaptic plasticity and Parkinson’s disease. In the workshop, international REGISTRATION experts will provide an overview of the scientific nyulmc.org/frescocme advances on different aspects of brain plasticity from After 12 pm on October 5, 2021 only onsite registration is bench to bedside in health and movement disorders. available, provided the meeting has not reached capacity. On the last day, NYU Langone faculty will present Onsite registrants will incur an additional $20 charge. didactic lectures, providing an overview of advances Registration is non-transferable. in diagnosis and treatment of Parkinson’s disease and related disorders. Participants will gain a deeper EACCME® ACCREDITATION STATEMENT understanding of brain function and its relevance The 2020 Fresco International Workshop to diagnosis and treatment of Parkinson’s disease, on Synaptic Plasticity and Advances in parkinsonisms, and movement disorders. Parkinson’s Disease, Florence, Italy, 12/10/2021–15/10/2021 has been EDUCATIONAL OBJECTIVES accredited by the European Accreditation Council for After this activity, participants should be able to: Continuing Medical Education (EACCME®) with 20 • Describe the mechanisms of plasticity and European CME credits (ECMEC®s). Each medical their relevance in the genesis and treatment specialist should claim only those hours of credit that of symptoms of Parkinson’s disease and he/she actually spent in the educational activity. parkinsonisms Through an agreement between the Union • Evaluate the latest development in the deep brain Européenne des Médecins Spécialistes and the stimulation treatment of Parkinson’s disease and American Medical Association, physicians may dystonia convert EACCME® credits to an equivalent number of • Assess the use of rehabilitation techniques in AMA PRA Category 1 CreditsTM. Information on the parkinsonisms process to convert EACCME® credit to AMA credit can be found at www.ama-assn.org/educatio /earn- • Integrate the latest technology in the diagnosis credit-participation-international-activities. and treatment of patients with Parkinson’s disease, parkinsonisms, and other movement disorders Live educational activities, occurring outside of Canada, recognised by the UEMS-EACCME® for • Identify non-motor problems in Parkinson’s ECMEC®s are deemed to be Accredited Group disease and determine specific treatments Learning Activities (Section 1) as defined by the • Utilize different types of testing to their full Maintenance of Certification Program of the Royal advantage and identify some of their limitations College of Physicians and Surgeons of Canada. as well as benefits in assessing patients with CCME® for CME accreditation of this event. Parkinson’s disease, parkinsonisms, and other movement disorders ITALIAN ACCREDITATION STATEMENT • Describe the role of glia activity in inflammation in Total of 23 CME credits. Course code: 6633-317921. neurodegenerative disorders Accreditation for: Physician, Nurse, Physiotherapist, • Recognize visual and speech changes associated Occupational Therapist, Speech-Language Therapist with Parkinson’s Disease and Psychologist. TARGET AUDIENCE Researchers, physicians, and other care providers in the field of neurology, internal medicine, rehabilitation medicine, neurosurgery psychiatry, geriatrics and
AGENDA 9:00 am A New Anatomical Perspective TUESDAY, OCTOBER 12, 2021 on the Connections Between 1:00 pm Registration Basal Ganglia and Cerebellum: 1:45 pm Welcome Remarks Functional Implications Paolo Fresco Angelo Quartarone, MD Robert I. Grossman, MD Cognition, Emotion, Autonomic Kenneth Langone Function and Cerebellum 2:00 pm Introduction to the Workshop Jeremy D. Schmahmann, MD M. Felice Ghilardi, MD Cerebellum Contribution Angelo Quartarone, MD to Pathophysiology of 2:10 pm Opening Panel—COVID-19 and Movement Disorders Possible Link with Parkinson’s Hyder A. Jinnah, MD Disease and Parkinsonism: Coffee Break From Bench to Bedside Cerebellum and Plasticity: David Sulzer, PhD A Target for Non-Invasive K Ray Chaudhuri, MD Peter Schmidt, PhD Stimulation Elena Moro MD, PhD John Rothwell, PhD Cerebellum and Plasticity: SESSION I: A Target for Invasive Stimulation From Emotion to Motion Andres Lozano, MD, PhD Moderators: Veronica Ghiglieri, PhD Panel Discussion Peter Schmidt, PhD 12:30 pm Lunch and Poster Session Hartwig R. Siebner, MD, DMSci 3:00 pm From Emotion to Motion: Cortical SESSION III: and Subcortical Contributions Parkinsonisms and Plasticity Edmund T. Rolls, MA, DPhil, DSc, Hon DSc Moderators: P aolo Calabresi, MD Chronic Stress: From Neuronal Massimo Cincotta, MD Plasticity to Neurodegeneration Giacomo Koch, MD, PhD Sheela Vyas, MD 2:30 pm Rehabilitation in Parkinsonisms Coffee Break Robert Iansek, PhD, FRACP Stress, Sex, and Plasticity Tau and the Cytoskeleton: Debra Bangasser, PhD Relevance to Synaptic Functional Movement Disorders: Damage, Plasticity, and Maladaptive Plasticity in the Neurodegenerative Diseases Limbic-Motor Circuitry Francesca Bartolini, PhD Mark Hallett, MD Tau and Plasticity Panel Discussion Michael Rowan, PhD 6:30 pm Adjourn Clinical Spectrum of Parkinsonisms: New Frontiers 6:45 pm Social Event: Cocktail Alessandro Di Rocco, MD & PD Art Exhibition Coffee Break Cortical Plasticity in WEDNESDAY, OCTOBER 13, 2021 Corticobasal Syndrome, 8:30 am CME Sign-In PSP, MSA, and Lewy Body Antonio Suppa, MD, PhD SESSION II: Panel Discussion Cerebellum: New Perspectives 6:30 pm Round Table: What Patients in Movement Disorders Want from Research Moderators: Matilde Inglese, MD, PhD 7:00 pm Adjourn Marco Molinari, MD, PhD Ulf Ziemann, PhD
AGENDA Towards Adaptive DBS: THURSDAY, OCTOBER 14, 2021 Retuning Gait Freezing in Parkinson’s Disease 8:30 am CME Sign-In Ioannis Isaias, MD, PhD SESSION IV: The Present and the Future Plasticity and Non-Motor Symptoms of FUS for Movement Disorders in Parkinson’s Disease Jose A. Obeso, MD, PhD Moderators: Vicenzo Di Lazzaro, MD Panel Discussion Simone Rossi, MD, PhD Final Remarks and Conclusion Mario Zappia, PhD Mark Hallett, MD 9:00 am Fatigue in PD: 6:00 pm Adjourn A Plasticity-Related Disorder? K Ray Chaudhuri, MD FRIDAY, OCTOBER 15, 2021 Vision and Plasticity in Parkinson’s Disease 8:00 am Welcome and Course Introduction M. Felice Ghilardi, MD Steven L. Galetta, MD Pain as Maladaptive Plasticity in Parkinson’s Disease SESSION I: Michele Tinazzi, MD, PhD Genetic and Inflammation Coffee Break Moderator: Un Kang, MD Sleep Disorders in PD: An 8:10 am Astrocytes in Ultimate Disorder of Plasticity? Neurodegenerative Disorders Raffaele Ferri, MD Shane A. Liddelow, PhD Macrobioma and Parkinson’s Glial Targeted Therapy in Disease: Cause, Effect, Huntington’s Disease: or Mere Association? The SIGNAL Trial Gonzalo Torres, PhD Andrew S. Feigin, MD Panel Discussion Inflammation and Genetics 12:30 pm Lunch and Poster Session in Parkinson’s Disease Giulietta M. Riboldi, MD, PhD SESSION V: Modeling Genetic Parkinson’s Does DBS Modulate Plasticity in Disease in Patient-Derived Parkinson’s Disease and Dystonia? Cell Systems Emanuele Frattini, MD Moderators: Giancarlo Comi, MD Leonardo Lopiano, MD, PhD Panel Discussion Elena Moro, MD, PhD SESSION II: 2:30 pm The Past, the Present, Non-Motor Symptoms and the Future of DBS of Parkinson’s Disease Alim-Louis Benabid, MD, PhD Subcortical Deep Brain Moderator: Andrew S. Feigin, MD Stimulation Modulates Cortical 9:35 am Visual Perception Mechanisms Excitability and Plasticity Biyu J. He, PhD Robert Chen, MBBChir, MSc, FRCPC Rehabilitative Potential of Artistic Motor Cortical Plasticity Experience in Patient with PD and Pathological Oscillatory Alberto Cucca, MD Activity in Dystonia Speech and DBS Diane Ruge, PhD Federica Avantaggiato, MD Coffee Break Panel Discussion Coffee Break
AGENDA SESSION III: Exercise Enhances DA Release and Basic Mechanism of Plasticity BDNF Levels in Mouse Striatum and Clinical Applications Guendalina Bastioli, PhD Moderator: Richard Tsien, PhD Panel Discussion 11:00 am Keynote Speaker: SESSION IV: Speech and Motor Learning Movement Disorders Video Rounds Michael A. Long, PhD 12:25 pm Video Rounds Dopamine Modulates the Andrew S. Feigin, MD size of Striatal Projection Steven J. Frucht, MD Neuron Ensembles Un Kang, MD Marta Maltese, PhD Mark Hallett, MD Enhancement of Axonal 1:00 pm Adjourn Dopamine Release by Leptin Maria Mancini, PhD GABA Co-Transmission from Dopaminergic Neurons as a Potential Candidate for Striatal Modulation Riccardo Melani, PhD MEETING FEES Early Registration Regular (Ending on August 11, 2021 at 11:59 pm EST) Young Investigators, Physicians, Researchers 40 years old $350 $410 Please note: This meeting is eligible for NYU Grossman School of Medicine Alumni discount. REFUND POLICY CONTACT INFORMATION Submit your request for a refund of meeting fees NYU Grossman School of Medicine more than $75 no later than 7 days before the Phone: 212-263-5295 meeting start date. No refunds will be issued for Email: cme@nyulangone.org cancellations or no-shows after that time. To request a refund, email cme@nyulangone.org. ITALIAN CONTACT INFORMATION A $75 administrative fee will be deducted. Fresco Parkinson Institute Italia Phone: +39 055 598999 MEETING CANCELLATION POLICY Email: info@frescoparkinsoninstitute.it If a meeting is cancelled due to inclement weather, insufficient enrollment, or any other reason, NYU PROVIDED BY Grossman School of Medicine will refund registration NYU Grossman School of Medicine fees in full. NYU Grossman School of Medicine will provide at least two weeks’ advance notice if cancelling due to insufficient enrollment and as soon as possible ABSTRACT SUBMISSION in all other circumstances. NYU Grossman School of We are accepting abstract submissions for poster Medicine is not responsible for any airfare, hotel, or presentation highlighting your research findings other non-cancellable costs incurred by the registrant. possible on the topic of the five sessions. Please submit your abstract with a maximum LOCATION of 250 words excluding title, authors, and Istituto degli Innocenti presenters to: FI-NRP@nyulangone.org and Piazza della Santissima Annunziata, 12 monica.norcini@nyulangone.org. 50122 Firenze Poster Dimensions: 24" x 36" (61 x 91 cm). Deadline for submission: September 14, 2021 The best abstract will be selected also for oral presentation discussion.
Non-Profit Org. U.S. Postage PAID The 2021 Fresco NYU Grossman School of Medicine New York, NY 550 First Avenue, MS1 195 Permit #8167 International Workshop New York, NY 10016 on Synaptic Plasticity and Advances in Parkinson’s Disease October 12–15, 2021 nyulmc.org/frescocme
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