March 22-23, 2019 -Miami, FL, USA-Biltmore Hotel, Coral Gables - LINNC.com
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LINNC SEMINAR - AMERICAS EDITION LINNC Seminar is a LINNC extension a Unique Concept with the Same Spirit! Photo courtesy of the Greater Miami Convention and Visitors Bureau, MiamiandBeaches.com PROGRAM March 22-23, 2019 Biltmore Hotel, Coral Gables -Miami, FL, USA- Live Interventional Neuroradiology, Neurology & Neurosurgery Course www.linnc.com
LINNC SEMINAR 2019 - AMERICAS EDITION COURSE LINNC US Seminar is transformed – and LINNC Americas is born! Finally, the Americas – all the Americas – have their own interventional DIRECTORS neuroradiology seminar! By popular demand, our well-received North American course, LINNC US seminar is expanding its horizons, transforming and becoming LINNC Americas 2019 and taking place in Miami! This new venue offers the very best for all our participants. Besides being known for its good weather and beautiful beaches, Miami is a leading global city with a reputation in Jacques MORET science, research and the arts – a multicultural and dynamic location for LINNC Americas. Well served and offering an easier access to our colleagues from throughout South, Central and North America, our move is in response to what we have heard from participants during our other seminars and underlines the international and cross-border nature of the work we advance together. Interventional neuroradiology has entered a new maturity and with that comes a renewed commitment from all of us at the LINNC family of neuroradiology, neurology and neurosurgery courses to ensure that the quality of information and the expertise gained from years of practice is effectively transmitted and openly exchanged. To do this, we Laurent SPELLE continually work to develop the curriculum and fine-tune our pedagogical approach so that those who participate in any LINNC seminar come away with a take-home experience that can immediately and positively influence their practice. Aside from offering a venue for all our colleagues throughout the Americas, the central and motivating force in LINNC Americas will be this very spirit that equally defines all LINNC seminars: • An open exchange of knowledge and experience; • The quality, quantity and diversity of the pre-recorded cases. This case library ensures Guiseppe LANZINO that the interaction with the audience and expert panels will be strengthened by concrete examples designed to illustrate the most complex situations and respond to any of your questions; • The willingness of all participants, from the leading professors to youngest fellows to learn together. This is the LINNC spirit and this is – with your participation – why we believe LINNC Americas will be the leading course for interventional neuroradiology, neurology and neurosurgery in the Western Hemisphere! We wish you a fruitful seminar. Sincerely, Course Directors
FACULTY FACULTY & SCIENTIFIC COMMITTEE Andres ARBELAEZ Alejandro BERENSTEIN Orlando M. DIAZ Hospital Pablo Tobón Uribe Cerebrovascular Center Institute for Academic Medicine, Universidad CES The Mount Sinai Hospital Houston Methodist Hospital Medellin, Colombia New York, USA Weill Cornell Medical College Houston, USA Michel FRUDIT Tudor G. JOVIN Giuseppe LANZINO Hospital Albert Einstein Cooper University Hospital Mayo Clinic Sao Paulo, Brazil Camden, USA Rochester, USA Luis A. LEMME PLAGHOS Italo LINFANTE Vitor MENDES PEREIRA CENBA - Consultorio Endovascular Miami Cardiac and Vascular Institute Toronto Western Hospital, Neurologico Buenos Aires Florida International University University Health Network Buenos Aires, Argentina Miami, USA University of Toronto Toronto, Canada Jacques MORET Raul G. NOGUEIRA Ronie Leo PISKE NEURI, the Brain Vascular Center Marcus Stroke & Neuroscience Center Beneficencia Portuguesa de sao Paulo Bicêtre Hospital - Paris Saclay University Grady Memorial Hospital Sao Paulo, Brazil Paris, France Atlanta, USA Elias RABAHI Laurent SPELLE Hospital Santa Mônica NEURI, the Brain Vascular Center Goiânia, Brazil Bicêtre Hospital - Paris Saclay University Paris, France 3
FRIDAY 22 MARCH 2019 EXPERT PANEL: Jacques MORET, Laurent SPELLE, Andres ARBELAEZ, Alejandro BERENSTEIN, Orlando M. DIAZ, Vitor MENDES PEREIRA, Raul G. NOGUEIRA, Ronie Leo PISKE, Elias RABAHI 8:00-12:40 MORNING 8:00 Welcome message - Jacques MORET, Laurent SPELLE 8:10 Presentation of the best cases submitted by attendees - “Y-stentriever” thrombectomy: dealing with a hard clot in basilar tip occlusion Lucas SCOTTA CABRAL, Brazil - Pseudo-occlusion and two exceptions to the rule Eytan RAZ, United States REC 8:30 Recorded Cases & Cases Discussion 90 min Brain AVM: Adult & Pediatric 10:00 Coffee break & Visit of the exhibition area REC 10:30 Recorded Cases & Cases Discussion 100 min Ischemic stroke and Aneurysm treatment 12:10 Industry sponsored Symposium* (See page 7) 12:40 Lunch Break 13:30-18:25 AFTERNOON REC 13:30 Recorded Cases focused on radial approach 60 min Aneurysm treatment 14:30 Industry sponsored Symposium* (See page 7) REC 15:00 Recorded Cases & Cases Discussion 55 min Aneurysm management 15:55 Coffee break & Visit of the exhibition area 16:25 Presentation of the best cases submitted by attendees - Anterior communicating artery embolization with two braided stents in “X” Elias RABAHI, Brazil - Endovascular occlusion of a complex MCA aneurysm through an ineffective Vitaly KISELEV, Russia double barrel bypass using FD - Combined endovascular and microsurgical approach for a left opercular AVM Stephanie LENCK, France - Mechanical Thrombectomy in a patient with previously treated Stephen GUERIN, United States giant fusiform aneurysm - Complex - Transitional basilar aneurysm treated with multiple FD’s telescoped: Boris PABON, Colombia Staged or Single session? - Posterior circulation flow diversion & delayed hemorrhage - Autopsy findings Ansaar T. RAI, United States REC 17:25 Recorded Cases & Cases Discussion 60 min Dural AV Fistula & Aneurysm management *These sessions do not offer continuing education credit 4
SATURDAY 23 MARCH 2019 Michel FRUDIT, Tudor G. JOVIN, Giuseppe LANZINO, Luis A. LEMME PLAGHOS, Italo LINFANTE, 8:00-12:30 MORNING 8:00 Presentation of the best cases submitted by attendees - Atypical aneurysm, atypical course, atypical treatment? Guilherme DABUS, United States - eCLIPs alternative for Intrasaccular ineligible cases Donald RICCI, Canada - Flow diversion in small vessels: how far can we go? Emanuele ORRU’, Canada REC 8:30 Recorded Cases & Cases Discussion 90 min Ischemic stroke and Aneurysm treatment 10:00 Coffee break & Visit of the exhibition area 10:30 Industry sponsored Symposium* (See page 7) REC 10:45 Recorded Cases & Cases Discussion 75 min Brain AVM & Aneurysm treatment 12:00 Industry sponsored Symposium* (See page 7) 12:30 Lunch Break 13:30-18:00 AFTERNOON REC 13:30 Recorded Cases & Cases Discussion 120 min Ischemic stroke & Dural AVF 15:30 Coffee break & Visit of the exhibition area 16:00 Presentation of the best cases submitted by attendees - Spinal AVF secondary to venous hypertension from pelvic AVF Charles A. RITCHIE, United States and a proposal for modified spinal AVF classification - Endovascular treatment with flow diverter stent Marco Antonio OCHOA SOLORZANO, Mexico of recanalized aneurysm with unexpected evolution - Endovascular bail-out after massive rupture for elective basilar tip aneurysm coiling David VOLDERS, Canada - Endovascular treatment of a ruptured vertebral artery fusiform Matthew TAON, United States aneurysm in the setting of contralateral subclavian steal REC 16:40 Recorded Cases & Cases Discussion 60 min Miscellaneous 17:40 Award of the best case submitted 17:50 Closing remarks *These sessions do not offer continuing education credit 5
LEARNING OBJECTIVES Upon completion of this activity, the learner should be able to: -Describe the indications of treatment for aneurysms, AVMs, specific AVMs such as of those of the marrow (spine and spinal cord), spinal dural AVMs; the management of complications, cerebral stroke, and also on percutaneous techniques and balance the beneficial outcomes from treatment procedures, endovascular or surgical, against the natural history of the disease. -Demonstrate the high-quality practice of interventional neuroradiology and neurosurgery in a team environment. -Review information regarding basic and clinical research in diseases, including techniques and technologies of interventional neuroradiology and neurosurgery. -Explain the role of imaging in the diagnosis and management of those neurovascular disorders. EDUCATIONAL METHODS • Lectures • Question and Answer Sessions • Recorded cases • Round Table Discussions • Audiovisual Presentations ACCREDITATION STATEMENT In support of improving patient care, this activity is planned and implemented by Mayo Clinic College of Medicine and Science, Live Interventional Neuroradiology & Neurosurgery Course (LINNC) and NEURI Brain Vascular Centre. Mayo Clinic College of Medicine and Science is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team. CREDIT STATEMENT Mayo Clinic College of Medicine and Science designates this live activity for a maximum of 14 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. AMA/ROYAL COLLEGE CANADA The American Medical Association (AMA) and the Royal College of Physicians and Surgeons of Canada (Royal College) have renewed their CME agreement. Under the new agreement, select activities approved for Royal College MOC Credits are eligible for conversion to AMA PRA Category 1 Credit ™. National Specialty Societies and Simulation Programs that have been approved by the Royal College as accredited CPD providers are covered by this agreement. UEMS/EACCME CME CREDIT RECOGNITION The American Medical Association (AMA) has an agreement of mutual recognition of continuing medical education (CME) credit with the European Union of Medical Specialties (UEMS). Under the terms of this agreement, renewed in 2010, the AMA will convert CME credit for live and e-learning activities certified by the European Accreditation Council for Continuing Medical Education (EACCME), the accrediting arm of the UEMS, to AMA PRA Category 1 Credit ™. European physicians can earn their ECMEC®s by attending live events that have been certified for AMA PRA Category 1 Credits ™. DISCLOSURES Each faculty member, including moderators and planning committee members, in the CME activity are required to complete a disclosure form. A copy of the MCSCPD Faculty Disclosure Policy is available in the congress bag. 6
E-POSTERS AREA • Did you know that all best cases submitted by attendees presented on stage, are also viewable in the E-POSTERS AREA located in the exhibition? • In addition, come and discover 8 clinical cases selected as E-posters: - Endovascular treatment of dural sinus thrombosis. J.J. GUTIERREZ BAÑOS, Colombia - Direct puncture and percutaneous nBCA embolization of a traumatic head and neck pseudoaneurysm. D. VOLDERS, Canada - Distal posterior communicating artery acute occlusion treated with mechanical thrombectomy J. KOVOOR, United States - Transvenous embolization of a ruptured thalamic AVM. S. LENCK, France - Staged X Stenting for a large ruptured Acom Aneurysm. S. LENCK, France - One patient, two endovascular techniques and three treated intracranial aneurysms in one session. G. SAAL, Perú - Giant MCA Aneurysm treated with FD: the importance of Windkessel Effect. B.PABÓN, Colombia - A Subarachoid Hemorrhage Before Christmas. V.M. PEREIRA, Canada INDUSTRY SPONSORED SYMPOSIA FRIDAY 22 MARCH 2019 12:10 - 12:40 - Industry sponsored Symposium - MicroVention Evolving treatment of wide neck bifurcation aneurysms. Ansaar T. RAI, United States 14:30 - 15:00 - Industry sponsored Symposium - Medtronic Objectives: data spotlight on safety and efficacy of Pipeline in small and medium ICA aneurysms from the PREMIER trial - Breaking Data- PREMIER Trial Results on Pipeline in Small and Medium Aneurysms. Ricardo A. HANEL, United States SATURDAY 23 MARCH 2019 10:30 - 10:45 - Industry sponsored Symposium - Cerenovus PULSERIDER the Houston Experience. Orlando M. DIAZ, United States 12:00 - 12:30 - Industry sponsored Symposium - Stryker Committed to Next Gen Innovation. - Next generation aspiration with AXS Vecta 74. Sudhakar SATTI, United States - S urpass Flow Diverter: A retrospective experience of 248 patients treated with 1 year follow up. Shahran DERAKHSHANI, United kingdom 7
Ingest more. The AXS Vecta 74 Aspiration Catheter is the fi rst extra-large bore aspiration catheter on the market, providing a 0.074in lumen designed to ingest the clot. AXS Vecta™ 74 Aspiration Catheter Redefine aspiration. Copyright © 2019 Stryker AP002436 v1.0
AXS Vecta™ Aspiration Catheter AXS Vecta 6. This device is coated with a hydrophilic coating at the Catheter part Vessel size in mm proximal end of the device for a length of 25 cm. Please RX ONLY Aspiration number (Vessel size in inches) refer to the Device Preparation Section for further Caution: Federal Law (USA) restricts this device to sale by or Catheter information on how to prepare and use this device to on the order of a physician. INC-11129-115 2.1-4mm (0.083in – 0.157in) ensure it performs as intended. Failure to abide by the See package insert for complete indications, AXS Vecta 71 INC-11129-125 2.1-4 mm (0.083in – 0.157in) warnings in this labeling might result in damage to the contraindications, warnings and instructions for use. INC-11129-132 2.1-4 mm (0.083in – 0.157in) device coating, which may necessitate intervention or INTENDED USE/INDICATIONS FOR USE INC-11597-115 2.2-4 mm (0.087in – 0.157in) result in serious adverse events. The AXS Vecta Aspiration System, including the AXS Vecta AXS Vecta 74 INC-11597-125 2.2-4 mm (0.087in – 0.157in) PRECAUTIONS Aspiration Catheter, Aspiration Tubing Set, and VC-701 INC-11597-132 2.2-4 mm (0.087in – 0.157in) 1. Store in a cool, dry, dark place. Cliq Aspirator Pump, is indicated in the revascularization of 2. Do not use kinked, damaged, or opened devices. patients with acute ischemic stroke secondary to intracranial CONTRAINDICATIONS 3. Use the device prior to the “Use By” date specified on large vessel occlusive disease (within the internal carotid, The AXS Vecta Aspiration Catheter has not been evaluated for the package. middle cerebral – M1 and M2 segments, basilar, and vertebral use in the coronary vasculature. Do not use automated high-pressure contrast injection 4. Exposure to temperatures above 54°C (130°F) may damage arteries) within 8 hours of symptom onset. Patients who are device. Do not autoclave. ineligible for intravenous tissue plasminogen activator (IV t-PA) equipment with the AXS Vecta Aspiration Catheter because it or who failed IV t-PA therapy are candidates for treatment. may damage the device. 5. Torqueing or moving the device against resistance may result in damage to the vessel or device. DEVICE DESCRIPTION ADVERSE EVENTS 6. Maintain a constant infusion of appropriate flush solution. The AXS Vecta Aspiration System consist of the AXS Vecta • Acute vessel occlusion 7. If flow through the device becomes restricted, do not Aspiration Catheter, the Aspiration Tubing Set, and the VC-701 • Air embolism attempt to clear the lumen by infusion. Remove and Cliq Aspirator Pump. • Allergic reaction and anaphylaxis from contrast media replace the device. The AXS Vecta Aspiration Catheter is a single lumen, flexible, • Arteriovenous fistula 8. Examine the device to verify functionality and to ensure variable stiffness catheter. It has a radiopaque marker band • Death that its size and shape are suitable for the specific on the distal end and a Luer hub at the proximal end. The AXS • Device malfunction procedure for which it is to be used. Vecta Aspiration Catheter shaft has a lubricious hydrophilic 9. The AXS Vecta Aspiration Catheter should be used only coating at the distal end (distal • Distal embolization • Emboli by physicians trained in percutaneous procedures and/or 25 cm) to reduce friction during use. The Scout Introducer may interventional techniques. be used in conjunction with the AXS Vecta Aspiration Catheter • False aneurysm formation to facilitate in the introduction of the AXS Vecta Aspiration • Hematoma or hemorrhage at the puncture site 10. The Scout Introducer should be used with a guidewire and Catheter into distal vasculature and aid in navigation to distal • Inability to completely remove thrombus microcatheter inserted when in vasculature. anatomy. The Scout Introducer has a lubricious hydrophilic • Infection 11. If using the AXS Vecta Aspiration Catheter for coating at the distal end to reduce friction during use. thrombectomy, monitor the canister fluid level and replace • Intracranial hemorrhage the canister if the fill level reaches 75% of the canister The inner lumen of the AXS Vecta Aspiration Catheters • Ischemia is compatible with the Scout Introducer, guide wires and volume micro catheters. The inner lumen of the Scout Introducer is • Kidney damage from contrast media 12. Administration of anticoagulants and antiplatelets should compatible with guide wires and micro catheters of an outer • Neurological deficit including stroke be suspended until 24 hours post-treatment. Medical diameter of less than 0.044in. • Risks associated with angiographic and fluoroscopic management and acute post stroke care should follow the Each package includes one AXS Vecta Aspiration Catheter, one radiation including but not limited to: alopecia, burns ASA guidelines. Scout Introducer, one hemostasis valve, and two peel-away ranging in severity from skin reddening to ulcers, cataracts, 13. Any neurological determination should be evaluated introducers. Dimensions of the AXS Vecta Aspiration Catheter and delayed neoplasia by urgent CT scan and other evaluations as indicated and Scout Introducer are included on the individual device • Sterile inflammation or granulomas at the access site according to investigator/hospital best practice. label. The AXS Vecta Aspiration Catheters are available in • Tissue necrosis 14. As in all surgical interventions, monitoring of intra- 3 different lengths, the device configurations including the • Vessel spasm, thrombosis, dissection or perforation procedural blood loss is recommended so that appropriate length of the Scout packaged with each catheter and the WARNING management may be instituted. recommended Microcatheter length is presented in the table 15. Limit the usage of the AXS Vecta Aspiration Catheter to Contents supplied STERILE using an ethylene oxide (EO) 1.0 below. arteries greater than the catheter’s outer diameter. process. Do not use if sterile barrier is damaged. If damage is found, call your Stryker Neurovascular representative. 16. Excessive aspiration with the distal tip of the AXS Vecta INC- INC- INC- INC- INC- INC- For single use only. Do not reuse, reprocess or resterilize. Aspiration Catheter covered by the vessel wall may cause Catheter part Reuse, reprocessing or resterilization may compromise vessel injury. Carefully investigate location of the distal tip 11129 11129 11129 11597 11597 11597 number under fluoroscopy prior to aspiration. -115 -125 -132 -115 -125 -132 the structural integrity of the device and/or lead to device fail-ure which, in turn, may result in patient injury, illness or 17. There is an inherent risk with the use of angiography and Catheter inner death. Reuse, reprocessing or resterilization may also create fluoroscopy. 0.071 0.071 0.071 0.074 0.074 0.074 diameter (in) a risk of contamination of the device and/or cause patient 18. When transporting the VC-701 Cliq pump, utilize the Distal catheter infection or cross-infection, including, but not limited to, the pump handle. outer diameter 0.082 0.082 0.082 0.083 0.083 0.083 transmission of infectious disease(s) from one patient to (in) another. Contamination of the device may lead to injury, illness Catheter or death of the patient. After use, dispose of product and working length 115 125 132 115 125 132 packaging in accordance with hospital, administrative and/or (cm) local government policy. Scout WARNINGS Introducer 133 143 150 133 143 150 length (cm) 1. The AXS Vecta Aspiration Catheter has not been evaluated for more than one (1) clot retrieval attempt. Recommended compatible 2. The AXS Vecta Aspiration Catheter was evaluated for an 150 160 160 150 160 160 average duration of direct aspiration of 4 minutes. microcatheter length (cm) 3. This product is intended for single use only, do not re- Recommended sterilize or reuse. Re-sterilization and/or reuse may result in compatible cross contamination and/or reduced performance. 0.044 0.044 0.044 0.044 0.044 0.044 4. When the catheter is exposed to the vascular system, microcatheter max max max max max max it should be manipulated while under high-quality outer diameter (in) fluoroscopic observation. Do not advance or retract Recommended the catheter if resistance is met during manipulation; compatible 0.038 0.038 0.038 0.038 0.038 0.038 determine the cause of the resistance before proceeding. guidewire outer max max max max max max 5. Operators should take all necessary precautions to limit diameter (in) X-Radiation doses to patients and themselves by using sufficient shielding, reducing fluoroscopy times, and The AXS Vecta Aspiration System is recommended for use in modifying X-Ray technical factors where possible. the following vessel size ranges based on non-clinical testing. Refer to Table 2.0 below. Stryker Neurovascular 47900 Bayside Parkway Fremont, CA 94538 strykerneurovascular.com Date of Release: FEB/2019 Copyright © 2019 Stryker AP002436 v1.0 EX_EN_US
Live Interventional Neuroradiology, Neurology & Neurosurgery Course JUNE 3 - 5, 2019 PARIS - FRANCE c arrousel du louvre SAVE THE DATE Toronto Paris Beijing New Dehli LIVE CENTERS COURSE DIRECTORS Santiago de Chile Jacques MORET Laurent SPELLE www.linnc.com
EXHIBITION FLOOR PLAN COURTYARD GRANADA BALLROOM COURTYARD COURTYARD Conference Room Lunch & Coffee Break Area E-POSTERS ALHAMBRA AREA BALLROOM 7 Exhibit Spaces 1 6 COURTYARD 2 3 4 5 LOBBY ELEVATORS Welcome Desk MARBELLA ROOM* MAIN BUILDING Entrance Hotel WE THANK OUR PARTNERS FOR THEIR SUPPORT Exhibitors Platinum sponsors 7 BALT MEDTRONIC with an Educational Grant 5 BIOMODEX MICROVENTION with an Educational Grant 3 CERENOVUS Gold sponsor 1 MICROVENTION CERENOVUS with an Educational Grant STRYKER with an Educational Grant 4 PHILIPS 2 SIM&CURE 6 STRYKER Marbella Room* Demonstration / Meeting Room - MICROVENTION 15
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