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FCF Fox Corporate Finance | FCF Life Sciences Life Sciences Venture Capital Monitor August 2020 Antibody Part of FCF Life Sciences Research Series Strategic Financing Advisory in Life Sciences
Agenda FCF LIFE SCIENCES O V E RV I E W
Overview Overview Service Portfolio Facts and Figures Focus on Biotechnology, MedTech and HealthTech Over Over Life Sciences Life Sciences Management Team of 100 years EUR 2bn FCF advises innovative companies on arranging, structuring and placing Advisory in aggregated Life Sciences Presentation 8 equity and debt transactions in a holistic financing strategy approach. Board Life Sciences transaction Integrated based in Munich Together with its industry advisors, FCF Life Sciences provides valuable experience volume1 Financial support on the strategic positioning of its clients Modeling Post- Over 4 Access to Strategic Financing Advisory Transaction 80 Leading regularly Support > 1000 completed Life EIB advisor published Life international FCF advises with its dedicated Life Sciences team on the following Investor Sciences in Europe Sciences investors transaction types: Screening transactions1 reports 1 including Professionals and Life Sciences Advisors Investor / IB Venture Capital Venture Debt Roadshow + + Life Sciences Research Series Growth Equity Due Diligence Support Venture Capital Monitor Public Equity Monitor Equity & Debt is a monthly is the most detailed Life Sciences Team Fundraising published overview analysis of Financing of venture capital European publicly Strategy listed companies, transactions of Life Advisory Sciences companies from the Life Closing Sciences sectors Arno Fuchs Dr. Mathias Sebastian Alexander Kuhn Assistance CEO Schott Sommer Analyst Director Associate Term Sheet Negotiation Venture Capital Report IPO Report analyses the latest examines recent IPO Execution Venture Capital IPO trends in the Support funding activities in Life Sciences sector, Life Dr. Alexandra Goll Claus Schalper Prof. Dr. Enno Spillner the Life Sciences with a strong focus Science Former Co-Founder & former Horst Domdey CFO Evotec General Partner CFO Pieris Pharma Co-Founder of Medigene Advisory sector in Europe on the comparison TVM Capital & board member BioM Board (extract from service portfolio) and the US of European and US characteristics 3
Executive Summary The FCF Life FCF Life Sciences Venture Capital Monitor Recipients Sciences Venture Capital Monitor is a is a monthly published overview of biotechnology, pharmaceutical, The FCF Life Sciences Venture Capital Monitor targets the following monthly published medical technology and healthcare technology companies, recipients: overview focusing on displaying venture capital financing trends in the European life ▪ Corporates / Executives ▪ Venture capital investors the venture capital science industry ▪ Institutional investors ▪ Family Offices / High- financing ▪ Private equity investors net-worth individuals environment in the ▪ Advisors biotechnology, Scope pharmaceutical, medical technology The selection of companies is based on the following criteria: Availability and healthcare technology ▪ Focus on transactions with European headquartered life science The FCF Life Sciences Venture Capital Monitor is available on FCF’s segments, and can companies and available deal volume website at “https://www.fcf.de/de/research/life-science-research“ be used as a quick ▪ Companies operating in the biotechnology, pharmaceutical, reference for medical technology, healthcare technology, services or other life Data investors, corporates science related sectors and professionals All input data is provided by Pitchbook or GlobalData and is not ▪ The therapeutics sector is further divided into the following independently verified by FCF. Ratio and multiple calculations are indications: Oncology, Cardiovascular, Central Nervous System, driven based on the input data available. For additional information Gastrointestinal, Hematological, Infectious Diseases, and disclaimer, please refer to the last page More advanced, Immunology, Metabolic, Ophthalmology, Rare Diseases, detailed and / or Respiratory, Diversified and Others customized reports are available upon request To recommend colleagues or fellow investors to be added to the If you have questions, comments or ideas, please do not hesitate mailing list, kindly send an email with the respective contact to contact us information 4
Agenda V E N T U R E C AP I TAL T R AN S AC T I O N S AUGUST 2020
European Venture Capital Transactions in Life Sciences August 2020 Deal Total Volume Raised Overview (YTD) # Date Company HQ Subsector Vertical - Indication / Stage Company Description Series (EURm) (EURm) Deal Synopsis Cumulative Financing Volume (EURm) Developer of monolithic 7,000 6,104 detectors and x-ray technology Monolithic Detectors / 1 31-08-20 G-ray CHE MedTech intended to make medical A 26 26 The company raised CHF 28 million of Series A venture on August 31, 2020. 6,000 On market imaging solutions more precise 5,000 and secure. 4,000 3,000 2,000 Operator of a biotech company 2020 The company raised EUR 4.5 million of Series A venture funding on August 31, 2020. 1,000 Biodol Biotech / Central Nervous System / intended to develop an 2019 2 31-08-20 FRA A 5 5 The funds will be used to develop FLT3 inhibitors for the treatment of chronic and 0 Therapeutics Pharma Pre-clinic innovative treatment for chronic neuropathic pain. Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec pain. Financing Volume (August 2020): EUR 300m Subsectors Indications1 Healthcare The company raised EUR 4.3 million of Series A venture funding on August 31, 2020, AI-based Real-World Developer of an AI-based real- Services putting the company's pre-money valuation at an estimated EUR 6.38 million. The 3 31-08-20 Semalytix DEU HealthTech Evidence Generation Tool / world evidence generation tool A 4 4 funds will be used to expand its business development with pharma companies and On market designed to ingest data. HealthTech Immunology the wider healthcare market. 3% Others 20% 29% 29% EUR EUR 6,104m 55% Biotech / 3,348m Manufacturer of on-demand Pharma 4% Customized Prosthetic customized prosthetic products The company raised EUR 430,000 of venture funding on August 31, 2020. The funds 22% Gastro- 5% 4 31-08-20 Anatomic Studios SWE MedTech Products / intended to empower and inspire -
European Venture Capital Transactions in Life Sciences August 2020 Deal Total Volume Raised Overview (YTD) # Date Company HQ Subsector Vertical - Indication / Stage Company Description Series (EURm) (EURm) Deal Synopsis Cumulative Financing Volume (EURm) The company raised GBP 9.73 million of Series A venture funding on August 20, 2020, Developer of a novel molecular 7,000 6,104 putting the company's pre-money valuation at GBP 16.06 million. The funding will be Biotech / Diagnostics / assay intended to broaden 6,000 9 20-08-20 Biofidelity GBR A 11 12 used to accelerate the development and clinical validation of oncology panels for Pharma Developing access to the highest precision treatment selection and patient monitoring in oncology, and to bring these assays 5,000 testing to all patients. rapidly to market through direct sale, partnering and collaboration. 4,000 3,000 2,000 Provider of a medical research 2020 Medical Research Data The company raised $12 million of Series A venture on August 19, 2020. The funding 1,000 data platform intended to 2019 10 19-08-20 Castor NLD HealthTech Platform / A 10 16 will be used by the company to build out its patient-facing technology, which includes 0 facilitate electronic data capture On market video-enabled consent to remotely enroll patients in clinical trials. Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec for medical research. Financing Volume (August 2020): EUR 300m Subsectors Indications1 Healthcare Developer of novel technology The company raised GBP 250,000 of venture funding on August 19, 2020. The funding Services Magnitude Healthcare Diagnostics / 11 19-08-20 GBR intended to discover and develop -
European Venture Capital Transactions in Life Sciences August 2020 Deal Total Volume Raised Overview (YTD) # Date Company HQ Subsector Vertical - Indication / Stage Company Description Series (EURm) (EURm) Deal Synopsis Cumulative Financing Volume (EURm) Developer of a healthcare The company raised EUR 8.2 million of venture funding on August 11, 2020. In 7,000 6,104 Online Doctor Consultation Healthcare platform intended to serve support of the transaction, the firm received debt financing in the form of a loan. The 6,000 17 11-08-20 Practio GBR Platform / - 8 8 Services patients with the help of local funds will be used to accelerate the deployment in the UK and to enter the German On market 5,000 pharmacies. market later this year with other countries to follow from 2021 onwards. 4,000 3,000 2,000 2020 Implant for Heart Valve Developer of an implant The company raised EUR 20 million of Series B venture funding on August 7, 2020. 1,000 2019 18 07-08-20 InnovHeart ITA MedTech Dysfunction / technology intended to minimally B 20 20 The funds will be used to complete the first in human clinical evaluation of the 0 On market replace the invasive mitral valve. company's unique system using a trans-apical approach. Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Financing Volume (August 2020): EUR 300m Subsectors Indications1 Healthcare Owner and operator of a The company raised $13 million of Series A venture on August 7, 2020. The proceeds Services Biotech / Infectious Diseases / biotechnology company intended will support the development of the HTI immunogen as a therapeutic vaccine against 19 07-08-20 Aelix Therapeutics ESP A 11 11 Pharma Phase II to develop a therapeutic vaccine HIV infection up to the completion of a Phase 2 proof-of-concept efficacy trial in HIV- HealthTech Immunology to help people with HIV. infected individuals. 3% Others 20% 29% 29% EUR EUR 6,104m 55% Biotech / 3,348m Pharma 4% Developer of an e-healthcare 22% The company raised EUR 6.1 million of Series A venture funding on August 6, 2020. Gastro- 5% E-Healthcare Application / application intended to provide MedTech intestinal 21% 20 06-08-20 Elma ESP HealthTech A 6 7 The funding raised will be used to boost product development, the business growth 12% On market quicker doctor-patient Infectious and expansion of the team to put to the service user. Oncology communication in Spain. Diseases Central Nervous System The company raised EUR 66 million of Series A venture funding on August 6, 2020, Top Company Origins Top Investor Origins Biotech / Oncology / Developer of T cell receptors putting the company's pre-money valuation at an estimated EUR 2.53 billion. The 21 06-08-20 T-Knife DEU intended for T cell therapy of A 66 132 funds will be used by the company to advance at least four programs into the clinic, Pharma Pre-clinic cancer. ramping-up preclinical work for additional selected proprietary pipeline candidates and Others discovering TCRs against novel targets. Others 24% 27% 31% 29% EUR EUR 9% 6,104m 6,104m Developer of a genome-analysis The company raised EUR 2.4 million of Pre-Series A venture funding on August 6, 15% 11% Genome-Analysis Platform / 12% 9% 22 06-08-20 Made of Genes ESP HealthTech platform designed to understand A 2 3 2020. The funds will be used to launch and promote its VITAL and HEALTH lines, as On market 13% 10% 10% human genomes. well as the a new product. Top 5 Deals Top 5 Investors Deal # of Deal Developer of a portable # Company HQ Volume Series # Investor HQ Deals Volume2 Portable Wheelchair wheelchair technology intended 23 06-08-20 Mooevo ESP MedTech Technology / -
European Venture Capital Transactions in Life Sciences August 2020 Deal Total Volume Raised Overview (YTD) # Date Company HQ Subsector Vertical - Indication / Stage Company Description Series (EURm) (EURm) Deal Synopsis Cumulative Financing Volume (EURm) 7,000 6,104 Developer of a health tech Audio Gadget / The company raised GBP 1.32 million of venture funding on August 5, 2020, putting 6,000 25 05-08-20 Kokoon GBR MedTech gadget designed to offer sleep - 1 6 On market the company's pre-money valuation at GBP 9.17 million. and relaxation using audio. 5,000 4,000 3,000 2,000 Developer of real-time and 2020 accurate intra-uterine monitoring The company raised GBP 3.9 million of Series A venture on August 3, 2020. The funds 1,000 Monitoring Device / 2019 26 03-08-20 VivoPlex GBR MedTech device built for optimization of A 4 6 will be used for a clinical feasibility study and to gain a European CE mark for its first 0 Developing fertility treatment and uterine product, which will enable them to sell their product in the market. Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec health. Financing Volume (August 2020): EUR 300m Subsectors Indications1 Healthcare Services HealthTech Immunology 3% Others 20% 29% 29% EUR EUR 6,104m 55% Biotech / 3,348m Pharma 4% 22% Gastro- 5% MedTech intestinal 21% 12% Infectious Oncology Diseases Central Nervous System Top Company Origins Top Investor Origins Others Others 24% 27% 31% 29% EUR EUR 9% 6,104m 6,104m 15% 9% 11% 12% 13% 10% 10% Top 5 Deals Top 5 Investors Deal # of Deal # Company HQ Volume Series # Investor HQ Deals Volume2 1 2Eyes Vision 600 B 1 Bpifrance 24 71 CureVac 2 560 G 2 Venture Kick 20 2 (NAS: CVAC) 3 LumiraDx 278 C Mercia Asset 3 11 7 Management Arvelle 4 205 A High-Tech Therapeutics 4 10 13 Gründerfonds Oxford 5 Nanopore 186 - 5 Novo Holdings 9 66 Technologies Source: PitchBook as of 15.09.2020; FCF Equity Research; GlobalData Note: All volumes in EURm; financing rounds without deal values are excluded 9 1Only includes biotechnology and pharmaceutical deals; 2 Proportional attribution of deal values to investors participating in a transaction (transaction volume / # investors by financing round)
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