3rd DHU 2020 Autumn School - Fibrosis and remodeling: from common pathways to personalized targets
←
→
Page content transcription
If your browser does not render page correctly, please read the page content below
3rd DHU 2020 Autumn School
Fibrosis and remodeling: from common
pathways to personalized targets
Report 2016
DHU 2020 training event
27-28 october 2016, Nantes - France
DHU 2020 training event
Autumn school “Fibrosis and remodeling: from common pathways to personalized targets”
Imprint
Publisher
2
DHU 2020
Project Management
Karine.cavailles@univ-nantes.fr
Authors
Karine Cavailles, Bertrand Cariou
Pictures
Jérémy Segard, Nantes, France
Date
15 november 2016
Please take note that the content of this document is property of the DHU 2020. If you wish to use some of
its written content, make reference to: DHU 2020 Autumn School report: “Fibrosis and remodeling: from
common pathways to personalized targets”, Nantes, France, november 2016.DHU 2020 training event
Autumn school “Fibrosis and remodeling: from common pathways to personalized targets”
Table of contents
1. INTRODUCTION ..................................................................................................................... 4
2. PROGRAMME ......................................................................................................................... 5
3
3. EVENT OUTCOME ................................................................................................................. 8
3.1. GENERAL INFORMATION ...................................................................................................... 8
3.2. SURVEY INFORMATION ........................................................................................................ 9
3.2.1. MEETING AND WORKSHOP .................................................................................................. 9
3.2.2. OPEN QUESTIONNAIRE ...................................................................................................... 10
3.3. WORKSHOPS .................................................................................................................... 12
3.4. SHORT ORAL COMMUNICATION AND POSTER SESSION ........................................................ 13
4. LIST OF PARTICIPANTS ...................................................................................................... 14
5. CONCLUSION ....................................................................................................................... 18
6. ACKNOWLEDGEMENTS ...................................................................................................... 19
7. APPENDIX ............................................................................................................................ 20
7.1. APPLICATION PROCEDURE FOR EACCME ACCREDITATION ................................................ 20DHU 2020 training event
Autumn school “Fibrosis and remodeling: from common pathways to personalized targets”
1. Introduction
The DHU 2020 "Personalized medicine for chronic diseases", provider of the organization of 2016 Autumn
school, brings together the strengths of healthcare, teaching and biomedical research from 2 Nantes
institutes: l’institut du thorax and l’institut des maladies de l’appareil digestif (IMAD), along with the
humanities and social sciences (HSS) strengths of the "Standards, Diseases and Societies" topic, CNRS team
UMR 6297 "Law and Social Change".
These structures are built around a translational project ranging from premature to elderly subjects and
aimed at promoting the development of personalized medicine for chronic diseases. 4
The present report on the third training event “Fibrosis and remodeling: from common pathways to
personalized targets” is part of the training initiatives of DHU 2020 to its graduate and post-graduate
students (Science, Medicine and HSS) and staff, focusing on personalized medicine for chronic diseases and
on the transformations induced by this concept.
According to the participants’ opinions, the meeting was an exciting fibrosis and remodeing symposium,
which presented the highlights of interdisciplinary research, bridging biology and medicine with statistics,
imaging and computational modeling sciences.
During this 2 days’ workshop, the invited lectures, short oral communication, poster sessions and workshop
sessions provided state of the art information from the above fields and more particularly on their
integration.
In addition to the training event of DHU 2020, the meeting also represented an excellent opportunity for
scientists and doctors to share their knowledge and experience. Importantly, the meeting was supported by
the CaSyM initiative (Coordinating Systems Medicine across Europe) whose program was presented during
a session. The European Accreditation Council for Continuing Medical Education (EACCME) also accredited
the event with 11 European CME credits (ECMEC).
91 participants from 7 countries attended the meeting. 21 of them were researchers, 17 were medical
doctors, and 6 Technicians or engineers. 17 of them were Master 2 Degree students (medical and
scientists), 17 were PhD students (science and HSS) and 2 post-doctoral researchers. Thus, the objective to
attract graduate and post-graduate students was reached with 39,6 % of participants.
It is to note that all participants received a certificate of attendance. The certificate helps students (Master
degree and PhD students) to get their training approved by our local University. No participant asked for
CME credits.DHU 2020 training event
Autumn school “Fibrosis and remodeling: from common pathways to personalized targets”
2. Programme
Thursday 27th October 2016
09:00 Registration
B. Cariou (Nantes University Hospital, DHU 2020, France)
09:30 5
Welcome
J. Guihaire (CCML, Le Plessis Robinson, France)
09:45
Bioartlung 2020 Project : towards a bioartificial lung ?
SESSION 1
B. Staels (Inserm UMR 1011, Institut Pasteur de Lille, Lille, France)
10:30
Non-alcoholic steatohepatitis and cardiovascular disease: modulation by PPAR agonists
11:00 Coffee break
L. Bertrand (Université catholique de Louvain, Brussels, Belgium)
11:30
AMPK, more than just a metabolic sensor in cardiac pathologies
A. Bouloumie (Inserm UMR 1048, I2MC, Toulouse, France)
12:00
Adipose tissue remodelling and metabolic diseases
12:30 Selected Oral Communication #5
12:40 Selected Oral Communication #7
12:50 Lunch / Poster Session 1
14:10 Selected Oral Communication #6
14:20 Selected Oral Communication #8
14:30 Selected Oral Communication #10DHU 2020 training event
Autumn school “Fibrosis and remodeling: from common pathways to personalized targets”
14:45 Workshop Session 1 : Methodological approaches
WS 01 WS 02 WS 03
C. Dina ; F. Simonet N. Piriou, CHU de Nantes N. Theret ; J. Coquet
Inserm UMR 1087 Nantes, F. Vaillant, Inserm U1045, Bordeaux, Irset-Inserm UMR 1085 Rennes,
France France France
Genetic statistics to identify Imaging of cardiac remodelling: technics and Computational modeling to
target tissues applications from animal models to clinical identify biomarkers and targets
practice
6
15:45 Coffee break
SESSION 2
D. Brutsaert (University of Antwerp, Antwerpen, Belgium)
16:15
Role of the endothelium in fibrosis and remodelling pathways
I. Laza (Columbia University, New York, USA)
16:45 Tissue-specific functional effect prediction of genetic variation and applications to complex trait
genetics
17:15 End of sessions
Friday 28th October 2016
R. Walczack (Genfit, Loos, France)
09:00
Pharmacological strategies to target common signaling mechanisms in fibrotic diseases: lessons from
the past and future objectives
09:45 Workshop Session 2 : Methodological approaches
WS 01 WS 02 WS 03
C. Dina ; F. Simonet N. Piriou, CHU de Nantes N. Theret ; J. Coquet
Inserm UMR 1087 Nantes, F. Vaillant, Inserm U1045, Bordeaux, Irset-Inserm UMR 1085 Rennes,
France France France
Genetic statistics to identify Imaging of cardiac remodelling: technics and Computational modeling to
target tissues applications from animal models to clinical identify biomarkers and targets
practiceDHU 2020 training event
Autumn school “Fibrosis and remodeling: from common pathways to personalized targets”
10:45 Coffee break
SESSION 3
P. Gérard (UMR1319 MICALIS, Jouy en Josas, France)
11:15
Role of the gut microbiota in liver diseases
C. Breynaert (Laboratory of Clinical Immunology, KU Leuven, Belgium)
11:45
Chronic intestinal inflammation and fibrosis: friends or foe?
7
12:15 Selected Oral Communication #1
12:25 Selected Oral Communication #4
12;35 Selected Oral Communication #9
12:45 Lunch / Poster Session 2
F. Perros (Inserm U 999, CCML, Le Plessis Robinson, France)
14:00
Chemotherapy-induced pulmonary veno occlusive disease
A. Yildirim (Helmholtz zentrum, Munich, Germany)
14:30
The role of fibroblast in small airway remodeling of COPD
15:00 Selected Oral Communication #2
15:10 Selected Oral Communication #3
15:20 Jury deliberations
15:30 Awards, questionnaire delivery and End of meeting
16:00 End of meetingDHU 2020 training event
Autumn school “Fibrosis and remodeling: from common pathways to personalized targets”
3. Event outcome
3.1. General information
Analyses of gender balance showed that men were more represented during the meeting with 49 males
and 42 females among the 91 participants (Figure 1). 11 invited speakers and 6 tutors from all over Europe
presented highlights of interdisciplinary research, bridging biology and medicine during plenary sessions,
8
with statistics, imaging and computational modeling sciences in the workshops.
Among the participants were researchers, MDs, postdoctoral researchers, PhD students, and master degree
students. The majority of participants were from France.
Figure 1: Workshop participants according to gender, country and position (n = 91).DHU 2020 training event
Autumn school “Fibrosis and remodeling: from common pathways to personalized targets”
3.2. Survey information
Questionnaires were given to each participant (Appendix 7.1) and the outcomes are summarized below.
3.2.1. Meeting and Workshop
The training event was helpful for my future career The event was well organized
and I would recommend it to fellow students
I totally agree
I totally agree
I agree 9
I agree
Neutral
Neutral
I decline
I decline
I would not
I would not
recommend it
recommend it
Course rooms were well equipped with appropriate I could find specific courses easily
media technology
I totally agree
I totally agree
I agree
I agree
Neutral
Neutral
I decline
I decline
I would not
I would not
recommend it
recommend it
Courses started and ended at time Topics were well addressed
I totally agree I totally agree
I agree I agree
Neutral Neutral
I decline I decline
I would not I would not
recommend it recommend it
Presentation were of high quality Speakers/Tutors were well prepared
I totally agree I totally agree
I agree I agree
Neutral Neutral
I decline I decline
I would not I would not
recommend it recommend it
Figure 2: Workshop survey questions and the distribution of answers (n = 25).DHU 2020 training event
Autumn school “Fibrosis and remodeling: from common pathways to personalized targets”
Speakers interacted well with audience I could follow the discussions
I totally agree I totally agree
I agree I agree
Neutral Neutral
I decline I decline
I would not I would not
recommend it recommend it
10
I did make a contribution to the discussion The discussion were well chaired
I totally agree I totally agree
I agree I agree
Neutral Neutral
I decline I decline
I would not I would not
recommend it recommend it
The offered courses were useful
I totally agree
I agree
Neutral
I decline
I would not
recommend it
Figure 2 (continued): Workshop survey questions and the distribution of answers (n = 25).
3.2.2. Open questionnaire
Outcome of the open questionnaire filled by participants attending the workshop (n = 17).
Answers were grouped and summarized accordingly.
1. What made you chose to attend the current workshop and what was the initial source of
information?
Thematic and topics of interest ; Increase scientific culture and vision ; Networking ; future
collaborations; Invited lecturer ; Recommendation from university and laboratory ; DHU 2020 mailing
2. What kind of association do you combine with personalized medicine ?DHU 2020 training event
Autumn school “Fibrosis and remodeling: from common pathways to personalized targets”
Patient’s education; Translational medicine; Research progress
3. Where do you see the beneficial aspects of personalized medicine ?
Better management of patients
Public health costs decrease
To better directing projects
Targeted treatments
11
4. According to your opinion, in which disease area could personalized medicine have the most impact?
Cancer; Chronic diseases (pulmonary, cardiovascular); neurological disorders; hereditary diseases;
inflammatory, auto-immune and infectious diseases
5. Have you visited the DHU 2020 website?
6. By preference ranking, what theme would you want the upcoming autumns school will address ?
mitochondrial dysfunction:
Aging
Allergic diseases / immune regulation and modulation / transplantation
Cells interactions / Fibroblasts / Endothelium
Computational research for personalized medicine
Energetic metabolism in pathological situation
Gut inflammatory diseases / enteric nervous system / neuronal impairment
Rare cardiovascular diseases modeling
Smooth muscle cells / arterial hypertension / heart failure
Stem cells and regenerative medicine
Systems medicineDHU 2020 training event
Autumn school “Fibrosis and remodeling: from common pathways to personalized targets”
3.3. Workshops
During the meeting, two series of 3 workshops have been organized successively, to allow participants to
attend at least 2 workshops.
A total of 54 Participants attended the workshops, where 6 tutors were at the student’s disposal. The tutors
were professors from local or foreign institutions who were responsible for the preparation of the course
materials for students.
WS 01 WS 02 WS 03 12
Tutors C.Dina N. Pirou N. Theret
F. Simonet F. Vailland J. Coquet
Thematic Genetic statistics to Imaging of cardiac remodelling: Computational modeling to
identify target tissues technics and applications from identify biomarkers and
animal models to clinical targets
practice
Number of 14 32 18
participants
The workshop of C. Dina and F. Simonet was about the use of genetic statistics to identify target tissues.
They presented Genome-wide association studies (GWAS) and discuss how it can help unravel the
molecular mechanisms through which genetic variation causes disease.
Participants could follow step by step a GWAs analysis, evaluate the results and review various tools
(bibliography, public databases) to identify pathways involved in human diseases. It was a good hands-on
tutorial. Despite the interest of the topic, only a few students participated to this tutorial, as it was a very
targeted and specific course.
The general opinion of participants was that N Piriou and F. Vailland presented a very stimulating and
interactive workshop session, as evidenced by the number of participants. They dealt with the technics and
applications of imaging of cardiac remodeling. They described various technics of cardiac imaging, such as
ultrasounds, magnetic resonance… and show their applications « from bench to bedside », with examples
in clinical practice and in animal models of cardiac disesases, illustrating the fundamental role of
remodeling imaging in clinical and pre-clinical research.
The last workshop was presented by N. Theret and J. Coquet around computational modeling and cell
signaling. Despite a very specific area, they also had a great success.
Participants, after a brief survey of different approaches used for dynamic modeling of cell signaling, could
become familiar with Kappa language and its application for modeling the extracellular matrix networks
involved in the activation of the transforming growth factor TGF-β.
Overall, the workshop participation was a success (59,3% of meeting participants) and participants were
very enthusiastic about the topics and how the workshops were conducted.DHU 2020 training event
Autumn school “Fibrosis and remodeling: from common pathways to personalized targets”
3.4. Short oral communication and poster session
A part of the interactivity of the event was short oral communications and poster sessions.
10 abstracts were received and reviewed by the local scientific committee. In order to give the opportunity
to young scientists and medical doctors to present their work, all abstracts were selected to be presented
as a poster and a short oral communication.
Concerning short oral presentations, speakers had 10 minutes for their presentation. Questions concerning 13
the presentation were asked during the poster session, were selected speakers had 5 minutes to present
their work. Tutors chosen among the local scientific committee were asked to challenge the young speakers
with questions and run an active discussion among students and participants.
The common opinion was that presentations selected were on a high scientific level and well-presented
and students participated successfully to the discussion.
Despite the low number of abstracts, there were more submitted abstracts than last year, with foreign
participants.
Figure 5 : Extract of posters presented during the poster sessionDHU 2020 training event
Autumn school “Fibrosis and remodeling: from common pathways to personalized targets”
4. List of participants
PARTICIPANTS
SURNAME FIRST NAME INSTITUTION
l'institut du thorax
Amosse Emeline Inserm UMR 1087
Arnaout Youssef Université de nantes 14
Arnaud Marine CHU de Nantes
Atger Florian University of Lausanne
Audineau Lucie Université de Nantes
Baro Isabelle Inserm UMR 1087
Bertrand Luc Université Catholique de Louvain
Bouloumie Anne I2MC / Inserm UMR1048
Bouttier Anne-Laure CHU de Nantes
Bregeon Jeremy Inserm UMR 913
Breynaert Christine University Hospitals Leuven
l'institut du thorax
Brosseau Carole Inserm UMR 1087
Brutsaert Dirk University of Antwerp
Camus Anne Inserm UMRS 791 - LIOAD
l'institut du thorax
Cariou Bertrand DHU 2020
Castan Laure Inserm UMR 1087
l'institut du thorax
Castro Claire Inserm UMR 1087
CHU de Nantes
Cavailles Karine DHU 2020
l'institut du thorax
Chadeuf Gilliane Inserm UMR 1087
l'institut du thorax
Charpentier Flavien Inserm UMR 1087
Chiffoleau Manon Université de Nantes
Chkir Olfa Université de nantes
Colas Luc CHU de Nantes
Coquet Jean IRSETDHU 2020 training event
Autumn school “Fibrosis and remodeling: from common pathways to personalized targets”
Coudreau Simon Université de nantes
Daniel Malo Université de nantes
Dhot Justine Université de nantes
l'institut du thorax
Dilasser Florian Inserm UMR 1087
l'institut du thorax
Dina Christian INSERM UMR 1087
15
Duplouye Pierre Université de Nantes
Durand Maxim Inserm UMR 1064
Fiore Tony Université de Nantes
l'institut du thorax
Fonteneau Andréa Inserm UMR 1087
Garçon Damien Université de Nantes
Gauthier Chantal Université de nantes
Gerard Philippe Institut Micalis / INRA
Giemza Johanna LINA
Glemain Alexandre Université de nantes
Gonzales Jacques Inserm UMR 913
Guihaire Julien Hôpital Marie Lannelongue
Harkous Emée Université de nantes
l'institut du thorax
Henrio Kelly Inserm UMR 1087
Henry Antoine Université de nantes
Hochman Clarisse CHU de Nantes
l'institut du thorax
Jacobi David Inserm UMR 1087
Karakachoff Matilde Inserm UMR 1087
l'institut du thorax
Klein Martin Inserm UMR 1087
Lamirault Guillaume l'institut du thorax
l'institut du thorax
Lauzier Benjamin Inserm UMR 1087
Laza Iuliana Columbia University
Le Gloan Laurianne CHU de NantesDHU 2020 training event
Autumn school “Fibrosis and remodeling: from common pathways to personalized targets”
l'institut du thorax
Le May Cédric Inserm UMR 1087
Le Vely Benjamin Université de nantes
Lefevre Chloé UMR 913 / CHU de Nantes
Léger Jean Other
Léger Anne-Marie Other
16
Levrel Clara l'institut du thorax
Loirand Gervaise Inserm UMR 1087
Lorton Fleur Université de nantes
l'institut du thorax
Magnan Antoine Inserm UMR 1087
Magrē Jocelyne Inserm UMR 1087
Maguy Ange University of Bern
l'institut du thorax
Merot Jean Inserm UMR 1087
Moreau François INSERM
Niel Clement LINA
Pabois Julie Université de nantes
l'institut du thorax
Patin Justine Inserm UMR 1087
Perigaud Christian CHU de Nantes
Perros Frederic Hôpital Marie Lannelongue
Persello Antoine Université de nantes
Pichelin Matthieu CHU de Nantes
Piriou Nicolas l'institut du thorax
Pochard Camille Inserm UMR 913
Poullaouec Cyrielle Université de nantes
Prat Valentine Inserm UMR 1087
l'institut du thorax
Prieur Xavier Inserm UMR 1087
Rolli-Derkinderen Malvyne Inserm UMR 913
Roudaut Meryl Inserm UMR 1087DHU 2020 training event
Autumn school “Fibrosis and remodeling: from common pathways to personalized targets”
Schreck Benoit CHU de Nantes
Segard Jérémy Other
l'institut du thorax
Si-Tayeb Karim Inserm UMR 1087
l'institut du thorax
Simonet Floriane INSERM UMR 1087
Staels Bart Institut Pasteur Lille
17
Tesse Angela Université de Nantes
Theret Nathalie IRSET
Trebouet Emmanuelle CHU de Nantes
Trochu Jean-Noel l'institut du thorax
Turrini Mauro Université Panthéon-Sorbonne
IHU LIRYC
Vaillant Fanny Hôpital Xavier Arnozan
Walczak Robert Genfit SA
Yildirim Ali Önder Comprehensive Pneumology CenterDHU 2020 training event
Autumn school “Fibrosis and remodeling: from common pathways to personalized targets”
5. Conclusion
To conclude, we can say that the 3rd DHU 2020 Autumn school “fibrosis and remodeling: from common
pathways to personalized targets” was a very exciting meeting, with high-level speakers and focus on
successful examples of research and practice of systems medicine.
According to the survey and questionnaire, the attempts were very successful and useful for all participants
and trainees.
18
Concerning the participation, there were fewer participants than for the last edition (91 vs 108 participants
in 2015), but with a great proportion of graduate and post-graduate students, thus reaching the teaching
objectives of this DHU2020 Autumn school.
Although we can point out that there have been little foreign participants, the meeting was very fruitful in
terms of national and international networking, particularly with invited speakers.
Indeed, the autumn school was also the occasion of short meetings organized on the sidelines of the
congress for the development of new collaborations.
Finally, given the success of this edition and that of the previous year, this event will be renewed under the
same format in autumn 2017.DHU 2020 training event
Autumn school “Fibrosis and remodeling: from common pathways to personalized targets”
6. Acknowledgements
The event DHU 2020 Autumn School “From systems biology to new targets and therapeutics” was
supported by the CASyM initiative.
Steering Committee
The following officials, as part of the Scientific Steering Committee, are involved in the scientific
coordination of DHU 2020 :
19
Stanislas Bruley des Varannes – IMAD Director
Bertrand Cariou – l’institut du thorax Director
Dominique Darmaun
Anne Chantal Hardy
Hervé Le Marec
Gervaise Loirand
Antoine Magnan
Michel Neunlist
Patricia Parnet
Richard Redon
Sylvie Sacher-Huvelin
Jean-Noel Trochu
Administrative office (Coordination) of DHU 2020 Autumn school
Karine Botturi-Cavaillès - Project Management DHU 2020
Direction de la Recherche
Département Partenariats et Innovations, CHU de Nantes, France
Local scientific and organising committee
Head
Bertrand Cariou – DHU 2020, CHU de Nantes, France
Members
Malvyne Derkinderen – IMAD, Inserm UMR 913, France
Christian Dina – l’institut du thorax, Inserm UMR 1087, CNRS UMR 6291, France
Alban Gaignard – CHU de Nantes, l’institut du thorax, Inserm UMR 1087, CNRS UMR 6291, France
Xavier Prieur – l’institut du thorax, Inserm UMR 1087, CNRS UMR 6291, France
Guillaume Lamirault – l’institut du thorax, Inserm UMR 1087, CNRS UMR 6291, France
Cédric Le May – l’institut du thorax, Inserm UMR 1087, CNRS UMR 6291, FranceDHU 2020 training event
Autumn school “Fibrosis and remodeling: from common pathways to personalized targets”
7. Appendix
7.1. Application procedure for EACCME accreditation
20
Subject : Request to obtain UEMS-EACCME® accreditation for the international
DHU2020 Autumn school
Nantes, 22.06.2016
Dear Sir or Madam,
The DHU2020 ”Personalized medicine for chronic diseases”, brings together the strengths of
healthcare, teaching and biomedical research from 2 institutes in Nantes, France : l’institut du
thorax and l’institut des maladies de l’appareil digestif (IMAD), along with the humanities and social
sciences (HSS) strengths of the "Standards, Diseases and Societies" topic, CNRS team UMR
6297 "Law and Social Change". These structures are built around a translational project ranging
from premature to elderly subjects and aimed at promoting the development of personalized
medicine for chronic diseases. It was established in 2013 by the Université de Nantes, the Nantes
University Hospital and Aviesan, the French Alliance for Life and Health Sciences.
The DHU2020 aims to develop training initiatives to its graduate and post-graduate students
(Science, Medicine and HSS) and staff, focusing on personalized medicine for chronic diseases
and on the transformations induced by this concept.
Since 2014, DHU2020 annually organizes its Autumn School with foreign and domestic lecturers.
This school brings 110 to 120 participants each year, from which more than 40 % are science or
medicine graduate and post-graduate students.
The 3rd Autumn school entitled “Fibrosis and remodeling : from common pathways to personalized
targets” , will take place in Nantes, France, from 27th to 28th October 2016 at the Chambre de
Commerce et d’Industrie de Nantes- Saint Nazaire. The School will be European, with the support
of our collaborative European networks. Chair of the organizing committee is Prof. Bertrand Cariou
(Faculty of Medicine, Nantes University and Nantes University Hospital). All lecturers have
extensive and highly cited bibliography in the field of fibrosis, remodeling and personalized
medicine. The Autumn School is an excellent opportunity for social networking of young future
scientists and doctors with senor colleagues and to exchange knowledge and experience.DHU 2020 training event
Autumn school “Fibrosis and remodeling: from common pathways to personalized targets”
The Autumn school will be organized around plenary sessions, oral and poster presentation 21
sessions, and 3 workshop sessions dedicated to master degree students, doctoral and post-
doctoral students, researchers, medical doctors and other medical professionals. The Autumn
school will include problem-based discussion, active participation in methodological approaches for
personalized medicine based workshops and oral presentation of young participants. 7 hours of
lectures and 2 hours of practical work will be carried out through the event. The acquired
knowledge will be examined at the end of the meeting. Participants will receive a certificate of
attendance.
We kindly ask the European Accreditation Council for Continuing Medical Education to approve
and accredit the school with European CME credits. We suggest accrediting the course with 10
European CME credits.
Yours sincerely,
Prof. dr. Bertrand Cariou,
Chair of the organizing committeeYou can also read
