WEBINARS A series of live, interactive 2021/22 - PVRI - Pulmonary Vascular ...

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WEBINARS A series of live, interactive 2021/22 - PVRI - Pulmonary Vascular ...
PVRI
The research continues.                                                Pulmonary Vascular
                                                                        Research Institute

                          WEBINARS
                           A series of live, interactive

                                                              2021/22
                              Please join us for these exciting new online meetings.

Preliminary PROGRAMME
WEBINARS A series of live, interactive 2021/22 - PVRI - Pulmonary Vascular ...
PVRI
                                                                                                                                               Pulmonary Vascular
                                                                                                                                                Research Institute

                                           “i am pleased to announce a series of
                                     webinars and online meetings that continue
                                          the fantastic work of the PVri for our
                                          global members and young scientists.”
Werner Seeger                                 in the absence of the PVri in-person meetings and symposia, these online
President 2020-2022,                         webinars will enable us to stay in contact with our worldwide community,
Justus-Liebig University Giessen,                            but also to explore and discuss important new research.
Germany
                                        Following the success of the DDS 2020 DiGiTal online Drug & Development
                                         Symposium in June 2020, we are excited to launch this series of interactive
                                         live webinars and look forward to active discussion and debate throughout
                                                                                                            the year.
                                    During the live webinar sessions, there will be plenty of time set aside for Q&A to encourage active
                                         participation from our audience. All presentations will be available to download after the event.
                                                           We encourage you to participate in this exciting new feature and register online.

                                                                                                              reGiSTraTion iS Free For PVri PaiD memberS.
WEBINARS A series of live, interactive 2021/22 - PVRI - Pulmonary Vascular ...
PVRI
                                                                                                                                                                                               Pulmonary Vascular
                                                                                                                                                                                                Research Institute

                                                                                                                                                       introducing the
                                                                                      Scientific organisers...
                                                                                                                                We would like to thank our Scientific organising Committee,

Our Scientific Leaders...
                                                                                                                    under the leadership of Patricia Thistlethwaite and Stephan rosenkranz,
                                                                                                                        for putting together such an outstanding programme of stimulating
                                                                                                                                                                             and novel talks.
                                                                                                                        Many thanks also to all chairs, speakers and abstract presenters for contributing to
                                                                                                                                                                                  this exciting new feature.
                  Patricia Thistlethwaite                       Stephen rosenkranz
                  • University of California,                   • University of Cologne,                                   Details of the abstract submission process and how to register for the webinars
                    San Diego, USA                                Germany                                                                                                           will soon be available.

Our Scientific Planning Committee...

              Sébastien bonnet                  allan lawrie                               Stelios orfanos                              rogerio Souza                               rebecca Vanderpool
              • Laval University,               • University of Sheffield,                 • University of Athens                       • University of Sao Paulo,                  • University of Arizona
                Canada                            UK                                         Medical School,                              Brazil                                      College of Medicine
                                                                                             Greece                                                                                   - Tuscon, USA
WEBINARS A series of live, interactive 2021/22 - PVRI - Pulmonary Vascular ...
PVRI
                                                                                                                                                                 Pulmonary Vascular
                                                                                                                                                                  Research Institute

 Webinars
                                                                                             Dates and topics for the webinar series in 2021:

coming up in
                                                                                              Wednesday          Wednesday              Wednesday            Wednesday
                                                                                              27 January         24 February            24 march              28 april
                                                                                                 2021                2021                 2021                  2021

   2021
                                                                                             around the globe:   Keynote lecture         Connection          Virtual poster
                                                                                              Global burden         session               between             discussion
                                                                                               of pulmonary                             CoViD-19 and           session 1
                                                                                               hypertension                              pulmonary
                                                                                                                                       vascular disease

         SaVe The DaTeS                                                                       Wednesday           Wednesday             Wednesday            Wednesday
                                                                                               26 may              23 June               28 July             25 august
                                                                                                 2021                2021                 2021                  2021

Calendar of
                                                                                              novel imaging      Joint Symposium          Pro-Con             The notch
                                                                                              approaches in        with the eSC:           debate             receptors:
                                                                                               pulmonary          The pulmonary           session 1         multi-regulators

events...
                                                                                              hypertension       circulation in the                             of Pah
                                                                                                patients            heart failure                            development
                                                                                                                     syndrome

                                                                                              Wednesday           Wednesday            Wednesday            Wednesday

PVri webinars arranged in 2021
                                                                                             29 September         27 october          24 november          15 December
                                                                                                 2021                2021                 2021                  2021
                                                                                              beyond Dna:        Joint Symposium       machine learning        Pro-Con
                                                                                               The unseen         with the iShlT:        and artificial     debate session 2:
Webinars take place on the last Wednesday of each month from                                   genome and         end-stage Pah           intelligence     medical vs surgical
15:00-17:00 GmT, so you can easily schedule these in your calendars.                           novel omics        - how and what      approaches for Ph:   or interventional
                                                                                              approaches to          do we do in       From screening to      therapy for
Click on each meeting for further information on chairs, speakers and presentation topics.         Ph                  2021?          novel drug targets         CTePh
WEBINARS A series of live, interactive 2021/22 - PVRI - Pulmonary Vascular ...
PVRI
                                                                                                                                                    Pulmonary Vascular
                                                                                                                                                     Research Institute

 Webinars
coming up in
                                                                                             Dates and topics for the webinar series in 2022:

   2022                                                                                       Wednesday
                                                                                              26 January
                                                                                                 2022
                                                                                                               Wednesday
                                                                                                               23 February
                                                                                                                 2022
                                                                                                                               Wednesday
                                                                                                                               30 March
                                                                                                                                 2022
                                                                                                                                                Wednesday
                                                                                                                                                 27 April
                                                                                                                                                   2022
         SAVE THE DATES
                                                                                               Vitual poster   Bone marrow       Aging and      The association
                                                                                                discussion     modulation of     pulmonary      between cancer
                                                                                                 session 2      pulmonary      hypertension:       and PH:
                                                                                                                 vascular      An endemic on     A tale of two
                                                                                                                 disease        the horizon?       diseases

Calendar of
events...
                                                                                              Wednesday
                                                                                               25 May
                                                                                                 2022
                                                                                                Paediatric
                                                                                                   PH

PVRI webinars arranged in 2022
Webinars take place on the last Wednesday of each month from
15:00-17:00 GMT, so you can easily schedule these in your calendars.
Click on each meeting for further information on chairs, speakers and presentation topics.
WEBINARS A series of live, interactive 2021/22 - PVRI - Pulmonary Vascular ...
Presentations
                                                                                                     If not all questions can be answered on the day,
                                                                                                all comments will be published and circulated to all

Webinar 1
                                                                                                                       participants after the webinar.

Date // 27 January 2021
                                      NOTE: All times indicated are Greenwich mean Time (GMT)

                        around the globe:
             Global burden of pulmonary hypertension

     Presentations:

     • The view of the World Heart Federation (WHF)

     • Role of WHO/NCDA in promoting global health with a focus on
       cardiovascular disease

     • Update on the Global Burden of PH Project of the Institute for
       Health Metrics and Evaluation (IHME)

     • PVRI GoDeep: Perspectives of a global meta-registry

     • Best abstract

     • Best abstract

   back to
  calendar
WEBINARS A series of live, interactive 2021/22 - PVRI - Pulmonary Vascular ...
Presentations
                                                                                                     If not all questions can be answered on the day,
                                                                                                all comments will be published and circulated to all

Webinar 2
                                                                                                                       participants after the webinar.

Date // 24 February 2021
                                      NOTE: All times indicated are Greenwich mean Time (GMT)

                   Keynote lecture session 2021

     Presentations:

     • Keynote lecture 1
       mHealth and wearables: Is this the dawn of a new age for
       cardiovascular medicine?

     • Keynote lecture 2
       The role of ion channels as multi-purpose regulators in PH

     • Best abstract

     • Best abstract

     • Best abstract

   back to
  calendar
WEBINARS A series of live, interactive 2021/22 - PVRI - Pulmonary Vascular ...
Presentations
                                                                                                   If not all questions can be answered on the day,
                                                                                              all comments will be published and circulated to all

Webinar 3
                                                                                                                     participants after the webinar.

Date // 24 march 2021
                                    NOTE: All times indicated are Greenwich mean Time (GMT)

             Connection between CoViD-19 and
                pulmonary vascular disease

     Presentations:

     • SARS-1, MERS, SARS-2 and more: Are coronavirus infections an
       ubiquitous part of our lives?

     • Endothelitis and aberrant angiogenesis: Mechanisms of COVID-19
       induced vascular injury

     • Venous thromboembolism in COVID-19: Prevalence and clinical picture

     • ACE-II receptors: Modulation of PVD in COVID-19?

     • Best abstract

     • Best abstract

   back to
  calendar
WEBINARS A series of live, interactive 2021/22 - PVRI - Pulmonary Vascular ...
Presentations
                                                                                                                   If not all questions can be answered on the day,
                                                                                                              all comments will be published and circulated to all

Webinar 4
                                                                                                                                     participants after the webinar.

Date // 28 april 2021
                            NOTE: All times indicated are Greenwich mean Time (GMT)

                                                                                                      Virtual poster discussion session 1
              Virtual poster discussion session 1
                                                                                      Presentations
     Presentations:

                                                                                      round 1 baSiC
     round 1 baSiC
                                                                                      Poster 1
     • Poster 1
     • Poster 2                                                                       Poster 2
     • Poster 3
                                                                                      Poster 3
     • Poster 4
     • Poster 5                                                                       Poster 4

     • Poster 6                                                                       Poster 5

                                                                                      Poster 6
     • round 2 CliniCal
     • Poster 1                                                                       round 2 CliniCal
     • Poster 2
                                                                                      Poster 1
     • Poster 3
     • Poster 4                                                                       Poster 2
     • Poster 5                                                                       Poster 3
     • Poster 6

   back to
  calendar
WEBINARS A series of live, interactive 2021/22 - PVRI - Pulmonary Vascular ...
Presentations
                                                                                                    If not all questions can be answered on the day,
                                                                                               all comments will be published and circulated to all

Webinar 5
                                                                                                                      participants after the webinar.

Date // 26 may 2021
                                     NOTE: All times indicated are Greenwich mean Time (GMT)

             novel imaging approaches in pulmonary
                     hypertension patients

     Presentations:

     • Update from the Fleischner Society Task Force for imaging in pulmonary
       hypertension

     • Molecular imaging of pulmonary vascular disease using microvascular
       endothelial cell ligands

     • MRI to assess pulmonary vascular changes and PH progression

     • Xenon magnetic resonance imaging signatures of PH

     • Synchrotron-based phase contrast micro-CT imaging of pulmonary
       vascular disease in human tissue and animal models

   back to
  calendar
Presentations
                                                                                                     If not all questions can be answered on the day,
                                                                                                all comments will be published and circulated to all

Webinar 6
                                                                                                                       participants after the webinar.

Date // 23 June 2021
                                      NOTE: All times indicated are Greenwich mean Time (GMT)

              Joint Symposium with the eSC:
       The pulmonary circulation in the heart failure
                       syndrome
     Presentations

     • The right ventricle in HFpEF

     • Genetic aspects in Group2 PH

     • Exercise haemodynamics in heart failure: What can we learn from
       invasive CPET?

     • Systemic consequences and interorgan cross-talk in heart failure and PH

     • Best abstract

     • Best abstract

   back to
  calendar
Presentations
                                                                                                    If not all questions can be answered on the day,
                                                                                               all comments will be published and circulated to all

Webinar 7
                                                                                                                      participants after the webinar.

Date // 28 July 2021
                                     NOTE: All times indicated are Greenwich mean Time (GMT)

                    Pro-Con debate session 1

Presentations

     Topic a:
     • role of pulmonary vascular pruning in Pah

     • PRO:
       A hopeless cause: The pulmonary vasculature is largely gone and
       irredeemable in PAH

     • CON:
       Remnants of lost pulmonary vasculature may be re-engaged in PAH

     Topic b:
     • Treatment of patients with mild Pah

     • PRO:
       Patients with mild pulmonary hypertension (mPAP 21-24) should be
       treated with PAH approved drugs

     • CON:
       Patients with mild pulmonary hypertension (mPAP 21-24) should NOT be
       treated with PAH approved drugs

   back to
  calendar
Presentations
                                                                                                    If not all questions can be answered on the day,
                                                                                               all comments will be published and circulated to all

Webinar 8
                                                                                                                      participants after the webinar.

Date // 25 august 2021
                                     NOTE: All times indicated are Greenwich mean Time (GMT)

                     The notch receptors:
             multi-regulators of Pah development

     Presentations:

     • Role of notch1 in experimental pulmonary hypertension

     • Notch-BMPR interactions in endothelium in PAH

     • Notch3 is a driver and biomarker for PAH

     • Notch3 lineage and pulmonary vasculopathy

     • Cardiopulmonary consequences of inhibiting DLL4

   back to
  calendar
Presentations
                                                                                                     If not all questions can be answered on the day,
                                                                                                all comments will be published and circulated to all

Webinar 9
                                                                                                                       participants after the webinar.

Date // 29 September 2021
                                      NOTE: All times indicated are Greenwich mean Time (GMT)

                  beyond Dna:
   The unseen genome and novel omics approaches
                      to Ph

     Presentations:

     • MicroRNAs and IncRNAs in right heart hypertrophy and failure

     • LncRNA as biomarkers/therapeutic agents for pulmonary diseases
       - prospective view

     • Epigenomics in pulmonary vascular remodelling

     • CITE-seq: Enabling single cell multi-omic analyses

     • Proteomics: From discovery research toward the clinic - novel AI
       perspectives?

   back to
  calendar
Presentations
                                                                                                       If not all questions can be answered on the day,
                                                                                                  all comments will be published and circulated to all

Webinar 10
                                                                                                                         participants after the webinar.

Date // 27 october 2021
                                        NOTE: All times indicated are Greenwich mean Time (GMT)

           Joint symposium with the iShlT:
   end-stage Pah - how and what do we do in 2021?

     Presentations:

     • When should a PH patient be considered for lung transplant?

     • Atrial septum defect creation or mechanical support for end-stage PAH

     • Lung and heart-lung transplant in 2021:
       How well do PAH patients do?

     • The future of artificial lungs

     • Timing and extent of ventricular reverse remodelling after lung transplant
       for PH

   back to
  calendar
Presentations
                                                                                                       If not all questions can be answered on the day,
                                                                                                  all comments will be published and circulated to all

Webinar 11
                                                                                                                         participants after the webinar.

Date // 24 november 2021
                                        NOTE: All times indicated are Greenwich mean Time (GMT)

             machine learning and artificial intelligence
                        approaches for Ph:
               From screening to novel drug targets

     Presentations:

     • Looking beyond the hype: Applied AI and machine learning in translational
       medicine

     • Computational network pharmacology in cardiovascular disease:
       Leveraging big data

     • Drug discovery using artificial intelligence engines: Challenges and
       opportunities

     • Utilising artificial intelligence to screen and diagnose iPAH

     • Best abstract

     • Best abstract

   back to
  calendar
Presentations
                                                                                                      If not all questions can be answered on the day,
                                                                                                 all comments will be published and circulated to all

Webinar 12
                                                                                                                        participants after the webinar.

Date // 15 December 2021
                                       NOTE: All times indicated are Greenwich mean Time (GMT)

               Pro-Con debate session 2:
       medical vs. surgical or interventional therapy
                         for CTePh

     Presentations:

     • PRO:
       Riociguat should be given to all CTEPH patients, regardless of timing of
       PEA/BPA

     • CON:
       Riociguat should be given only to patients with inoperable or residual
       CTEPH after PEA/BPA

     • Best abstract
     • Best abstract
     • Best abstract
     • Best abstract
     • Best abstract

   back to
  calendar
Presentations
                                                                                           If not all questions can be answered on the day,
                                                                                      all comments will be published and circulated to all

Webinar 13
                                                                                                             participants after the webinar.

Date // 26 January 2022
                            NOTE: All times indicated are Greenwich mean Time (GMT)

              Virtual poster discussion session 2

     Presentations:

     round 1 baSiC
     • Poster 1
     • Poster 2
     • Poster 3
     • Poster 4
     • Poster 5
     • Poster 6

     • round 2 CliniCal
     • Poster 1
     • Poster 2
     • Poster 3
     • Poster 4
     • Poster 5
     • Poster 6

   back to
  calendar
Presentations
                                                                                                     If not all questions can be answered on the day,
                                                                                                all comments will be published and circulated to all

Webinar 14
                                                                                                                       participants after the webinar.

Date // 23 February 2022
                                      NOTE: All times indicated are Greenwich mean Time (GMT)

             bone marrow modulation of pulmonary
                       vascular disease

     Presentations:

     • Role of bone marrow in the pathogenesis of PAH

     • Role of bone marrow in the right ventricle remodelling

     • Reversal of PH by whole bone marrow transplantation in BMPR2
       deficient mice

     • Bone marrow dependency of cigarette smoke-induced PH versus
       emphysema

     • Homologous bone marrow transplantation prevents the development
       of PAH in patients with severe scleroderma

   back to
  calendar
Presentations
                                                                                                    If not all questions can be answered on the day,
                                                                                               all comments will be published and circulated to all

Webinar 15
                                                                                                                      participants after the webinar.

Date // 30 march 2022
                                     NOTE: All times indicated are Greenwich mean Time (GMT)

             aging and pulmonary hypertension:
                 an endemic at the horizon?

     Presentations:

     • Age-dependent prevalence of PH in the general population

     • Senescence mechanisms and pulmonary vascular aging

     • Metabolic syndrome and obesity leads to age-related PH

     • Genetics and epigenetics in age-related PH

     • Best abstract

     • Best abstract

   back to
  calendar
Presentations
                                                                                                    If not all questions can be answered on the day,
                                                                                               all comments will be published and circulated to all

Webinar 16
                                                                                                                      participants after the webinar.

Date // 27 april 2022
                                     NOTE: All times indicated are Greenwich mean Time (GMT)

             The association between cancer and Ph:
                      a tale of two diseases

     Presentations:

     • Cancer induced PH: Embolism as a major inducer

     • Cancer induced PH: Microenvironmental cancer niche as a major inducer

     • Cancer therapies induced PH

     • Cancer related signalling mechanisms underlying PH development

     • Best abstract

     • Best abstract

   back to
  calendar
Presentations
                                                                                                     If not all questions can be answered on the day,
                                                                                                all comments will be published and circulated to all

Webinar 17
                                                                                                                       participants after the webinar.

Date // 25 may 2022
                                      NOTE: All times indicated are Greenwich mean Time (GMT)

                               Paediatric Ph

     Presentations:

     • Genetics of pulmonary arterial hypertension: What we can learn by
       studying children with and without congenital heart disease

     • Therapeutic options in advanced PVD: Potts shunt versus lung
       transplantation

     • Stem cells and regenerative medicine for neonatal lung disease:
       Implications for COPD

     • Assessment of operability in patients with congenital heart disease
       and PAH: Fallacies and pitfalls

     • Best abstract

     • Best abstract

   back to
  calendar
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                                                           Pulmonary Vascular
                                                            Research Institute

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                            The PVRI is a Registered Charity in the UK, No: 1127115.
                            Disclaimer: This programme and its contents are correct at the time of printing.
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