Update on COVID-19 Projections - Science Advisory and Modelling Consensus Tables June 10, 2021 - Ontario COVID-19 Science ...
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Key Findings • Cases, percent positivity, and hospitalizations have all dropped sharply thanks to the commitment of Ontarians. • Cases should continue to decline for the next 10 days. As vaccination continues, it will be important to monitor carefully for new variants and continue assessing for signs of breakthrough and serious infection. • The Delta variant is more transmissible and may be more dangerous. It will likely be the dominant form of the virus this summer. It is critical to control the spread of this variant. • To avoid a fourth wave, we need to continue to ensure first and second doses in high-risk communities, continue tailoring vaccine clinics to community needs, and ensure strong testing and case and contact tracing. 2
Weekly new cases per 100,000 residents 100 150 200 300 250 50 0 Data source: CCM Porcupine Thunder Bay Peel Hamilton Brant Durham Data note: Data for the most recent day have been censored to account for reporting delays Waterloo Toronto Niagara York Wellington-Dufferin-Guelph Middlesex-London Windsor-Essex Ottawa Haliburton KPR May 24 Halton Simcoe Muskoka Lambton Huron Perth Haldimand-Norfolk Average weekly cases on: Peterborough June 6 Southwestern Renfrew Chatham-Kent Eastern Grey Bruce Sudbury North Bay Parry Sound KFLA Hastings & PEC Northwestern Algoma Cases have decreased sharply in almost all Public Health Units Timiskaming Leeds Grenville Lanark 3
% positivity has declined sharply since the last briefing Dec 26 Jan 18 Apr 3 Apr 17 Province-wide lockdown First dose Province-wide Enhanced public health % positivity of daily testing episodes 14-days for N. Ontario vaccination emergency brake measures and enforcement 28-days for S. Ontario In LTC in 18 prioritized PHUs 16 14 (7-day avg.) 12 10 Porcupine, 9.5% 8 Peel, 6.3% 6 Hamilton, 6.1% Waterloo, 5.5% 4 Toronto, 4.0% Ontario, 3.2% 2 0 May 22 Aug 15 Aug 29 Nov 21 Mar 13 Mar 27 Apr 10 Apr 24 Oct 10 Oct 24 Feb 27 Dec 19 Feb 13 Sep 12 Sep 26 Jan 16 Jan 30 May 8 Aug 1 Nov 7 Dec 5 Jun 5 Jan 2 Specimen Date 4 Data source:Ontario Laboratory Information System (OLIS), data up to June 4
Testing has declined. Continued strong monitoring will be critical for control of the pandemic. 700 Testing episodes per 100,000 600 500 (7-day avg.) Porcupine, 442 400 300 200 Ontario, 172 100 Timiskaming, 107 0 May 22 Aug 15 Aug 29 Nov 21 Mar 13 Mar 27 Apr 10 Apr 24 Oct 10 Oct 24 Feb 13 Feb 27 Dec 19 Sep 12 Sep 26 Jan 16 Jan 30 May 8 Aug 1 Nov 7 Dec 5 Jun 5 Jan 2 Specimen Date 5 Data source:Ontario Laboratory Information System (OLIS), data up to June 4
COVID-19 hospitalizations and ICU occupancy have dropped 2500 Patients in Inpatient Beds with COVID19 2000 Patients in ICU with COVID-Related Critical Illness 1500 1000 500 0 Data Sources: MOH COVID Inpatient Census and Critical Care Information System 6
Continuing control of the pandemic will be key to reducing the access-to-care deficit 150% 100% Most urgent surgeries Change vs Previous Year† (%) HOLIDAYS 50% 0% Semi urgent surgeries Least urgent… -50% -100% Apr 2020 May Jun Jul Aug Sep Oct Nov. Dec Jan. 2021 Feb Mar Apr May Data Source: Wait Times Information System 7 2020 2021
Ontarians’ commitment to public health measures means we are doing much better since the last briefing 5,000 Figure shows 4,500 predictions based on 4 4,000 models. 3,500 • Partial reopening June 3,000 Daily Cases 14 2,500 Range from • Vaccinating 140k- 2,000 last briefing 180k/day 1,500 • Delta VOC considered 1,000 • Different levels of 500 disease spread after - Step 1 opening 03/05 04/23 01/01 01/08 01/15 01/22 01/29 02/05 02/12 02/19 02/26 03/12 03/19 03/26 04/02 04/09 04/16 04/30 05/07 05/14 05/21 05/28 06/04 06/11 06/18 06/25 07/02 07/09 07/16 07/23 07/30 08/06 08/13 ON - Daily ON - 7-Day Average High, 142k/day High, 180k/day Medium, 142k/day Medium, 180k/day Low, 142k/day Low, 180k/day Predictions informed by modeling from Fields Institute, McMasterU, PHO, YorkU Data (Observed Cases): covid-19.ontario.ca 8
If we continue to control COVID-19, we can drop below 200 COVID- 19 patients in ICUs by mid-July and begin to resume normal hospital operations ICU Occupancy 1,000 Range from 900 last briefing 800 700 600 500 400 300 200 100 - 03/18 05/06 12/31 01/07 01/14 01/21 01/28 02/04 02/11 02/18 02/25 03/04 03/11 03/25 04/01 04/08 04/15 04/22 04/29 05/13 05/20 05/27 06/03 06/10 06/17 06/24 07/01 07/08 07/15 ON - Daily ON - 7-Day Average Predicted High, 142k/day High, 180k/day Medium, 142k/day Medium, 180k/day Low, 142k/day Low, 180k/day Predictions: COVID-19 ModCollab. 9 Data (Observed ICU Occupancy): CCSO
The 2nd vaccine dose is more than 2x as effective against the Delta variant – it is key to get 2nd doses in arms Delta variant (B.1.617.2) • About 50% more transmissible than Alpha (B.1.1.7) • Will likely be the dominant variant in the early summer • Risk of hospitalization may be increased • 1st dose of vaccine less effective against symptomatic disease but it may protect against severe disease Source: SARS-CoV-2 variants of concern and variants under Source: Estimated from Bernal et al, BMJ 2021; Bernal et al, medRxiv 2021 10 investigation in England Technical briefing 14
Continuing a strategy based on age and community risk will help control the spread and impact of the Delta variant Protect all regions with 1st doses, avoid Protect regions at high-risk of Delta with ‘pockets’ with low coverage increased 1st and 2nd dose coverage • Minimize risk of introduction and • Control surges in Delta-high-risk areas propagation of Delta-variant • Minimize risk of spillover into other areas • Continue core public health functions of • Continue core public health functions of case and contact tracing, testing case and contact tracing, testing Benefits of continuing a focus on high-risk communities • Compared to a pure age-based allocation, continuing a high-risk community strategy reduces the overall case count by 39% (both with 2nd dose eligibility at 6 weeks) • Much of the reduction in cases are in lower-risk communities; benefitting all communities Technical Note: Modelling based on 2nd dose coverage of 45% in high-risk regions and 25% in all other regions by the end of June, 70% 1st dose coverage for all regions 11
Vaccination coverage continues to increase Provincial progress (Age 18 or older) 72.8% 27.2% 2,500,000 2,000,000 Population remaining 1,500,000 Has made an appointment for first dose* 1,000,000 Number of individuals 500,000 with at least one dose - 80+ 70 to 79 60 to 69 50 to 59 40 to 49 30 to 39 18 to 29 12 to 17 * Note that this is just Pending Appointments. Anyone who has made an appointment and received a vaccine will be counted under “Individuals with at least one dose”. Data for Appointments reflect 21 PHUs that are captured through the provincial booking system. Appointments made through other systems (e.g., local PHU booking systems, pharmacies, primary care) are not included. ^ Age is based on year of birth. Data Sources MOF 2020 Population Projections COVAX analytical file, extracted 8:00pm June 6 2021, CPAD, MOH COVAX Skedulo, extracted 6:00pm June 6 2021 12
The high-risk community strategy has helped Figure excludes long-term care vaccination – at least 1 dose as of June 7, 2021 Source: ICES 13
Key Findings • Cases, percent positivity, and hospitalizations have all dropped sharply thanks to the commitment of Ontarians. • Cases should continue to decline for the next 10 days. As vaccination continues, it will be important to monitor carefully for new variants and continue assessing for signs of breakthrough and serious infection. • The Delta variant is more transmissible and may be more dangerous. It will likely be the dominant form of the virus this summer. It is critical to control the spread of this variant. • To avoid a fourth wave, we need to continue to ensure first and second doses in high-risk communities, continue tailoring vaccine clinics to community needs, and ensure strong testing and case and contact tracing. 14
Contributors • COVID Vaccination Strategy Modeling Group: Sharmistha Mishra, Jesse Knight, Huiting Ma, Kevin Brown, Amir Ghasemi, Kamil Malikov, Michael Paterson, Hannah Chung, Andrew Calzavera, Kinwah Fung, Kristy Yiu, Sarah Buchan, Sarah Wilson, Leigh Hobbs, Linwei Wang, Stefan Baral, Rafal Kustra, Gary Moloney, Nathan Stall, Jeff Kwong, Peter Jüni & Beate Sander • COVID-19 Modeling Collaborative: Kali Barrett, Stephen Mac, David Naimark, Aysegul Erman, Yasin Khan, Raphael Ximenes, Sharmistha Mishra, Beate Sander • Fields Institute: Taha Jaffar, Kumar Murty • ICES: Jeff Kwong, Hannah Chung, Kinwah Fung, Michael Paterson, Susan Bronskill, Laura Rosella, Astrid Guttmann, Charles Victor, Michael Schull, and Marian Vermeulen • McMasterU: Irena Papst, Michael Li, Ben Bolker, Jonathan Dushoff, David Earn • YorkU: Jianhong Wu, Yanyu Xiao, Zack McCarthy • MOHLTC: Michael Hillmer, Kamil Malikov, Qing Huang, Jagadish Rangrej, Nam Bains, Jennifer Bridge • OH: Erik Hellsten, Stephen Petersen, Anna Lambrinos, Chris Lau, Access to Care Team • PHO: Kevin Brown • Science Advisory Table: Peter Juni, Antonina Maltsev, Bruno da Costa 15
Content provided by Modelling Consensus and Scientific Advisory Table members and secretariat Beate Sander,* Peter Juni, Brian Schwartz,* Kumar Murty,* Upton Allen, Vanessa Allen, Kali Barrett, Nicholas Bodmer, Isaac Bogoch, Kevin Brown, Sarah Buchan, Yoojin Choi, Troy Day, Laura Desveaux, David Earn, Gerald Evans, David Fisman, Jennifer Gibson, Anna Greenberg, Anne Hayes,* Michael Hillmer, Jessica Hopkins, Jeff Kwong, Fiona Kouyoumdjian, Audrey Laporte, John Lavis, Gerald Lebovic, Brian Lewis, Linda Mah, Kamil Malikov, Antonina Maltsev, Doug Manuel, Roisin McElroy, Allison McGeer, David McKeown, John McLaughlin, Sharmistha Mishra, Justin Morgenstern, Andrew Morris, Samira Mubareka, Laveena Munshi, Christopher Mushquash, Ayodele Odutayo, Shahla Oskooei, Menaka Pai, Samir Patel, Anna Perkhun, Bill Praamsma, Justin Presseau, Fahad Razak, Rob Reid,* Paula Rochon, Laura Rosella, Michael Schull, Arjumand Siddiqi, Chris Simpson, Arthur Slutsky, Janet Smylie, Nathan Stall, Robert Steiner, Ashleigh Tuite, Jennifer Walker, Tania Watts, Ashini Weerasinghe, Scott Weese, Xiaolin Wei, Jianhong Wu, Diana Yan, Emre Yurga * Chairs of Scientific Advisory, Evidence Synthesis, and Modelling Consensus Tables For table membership and profiles, please visit the About and Partners pages on the Science Advisory Table website. 16
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