STUDY PROGRAM 2021/2022 Subjects of the 7-8. semesters (obligatory subjects and criterion requirements)

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UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

                                 University of Pécs
                                Faculty of Pharmacy

                                            PHARMACY
                                              Major

                      STUDY PROGRAM
                         2021/2022

                   Subjects of the
                   7-8. semesters
             (obligatory subjects and
              criterion requirements)

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UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

Table of Contents

7th semester
OPG-C3E-T          Pharmaceutical Technology 3 - Theory ____________________________________________________________ 3
OPG-C3G-T          Pharmaceutical Technology 3 - Practice____________________________________________________________ 5
OPG-D1E-T          Pharmacodynamics 1 - Theory ___________________________________________________________________ 8
OPG-D1G-T          Pharmacodynamics 1 - Practice _________________________________________________________________ 11
OPG-GAI-T          Pharmaceutical Applied Immunology ____________________________________________________________ 13
OPG-GI2-T          Pharmaceutical Practice and Management 1 _______________________________________________________ 15
OPG-PPA-T          Pharmaceutical Pathology _____________________________________________________________________ 18
OPG-R3E-T          Pharmaceutical Chemistry 3 - Theory ____________________________________________________________ 20
OPG-R3G-T          Pharmaceutical Chemistry 3 - Practice ____________________________________________________________ 23
OPO-KE1-T          Public Health 1 ______________________________________________________________________________ 26

8th semester
OPG-C4E-T          Pharmaceutical Technology 4 - Theory ___________________________________________________________ 28
OPG-C4G-T          Pharmaceutical Technology 4 - Practice___________________________________________________________ 30
OPG-D2E-T          Pharmacodynamics 2 - Theory __________________________________________________________________ 32
OPG-D2G-T          Pharmacodynamics 2 - Practice _________________________________________________________________ 35
OPG-GBI-T          Pharmaceutical Biotechnology __________________________________________________________________ 37
OPG-KL1-T          Clinical Studies 1 ____________________________________________________________________________ 39
OPG-R4E-T          Pharmaceutical Chemistry 4 - Theory ____________________________________________________________ 41
OPG-R4G-T          Pharmaceutical Chemistry 4 - Practice ____________________________________________________________ 43
OPG-TXA-T          Toxicology _________________________________________________________________________________ 46
OPG-U3E-T          Pharmaceutical Practice and Management 2 - Theory ________________________________________________ 49
OPG-U3G-T          Pharmaceutical Practice and Management 2 - Practice _______________________________________________ 53
OPO-KE2-T          Public Health 2 ______________________________________________________________________________ 55

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UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

OPG-C3E-T              PHARMACEUTICAL TECHNOLOGY 3 - THEORY
Course director:                                                                                 DR. SZILÁRD PÁL, assistant professor
                                                      Institute of Pharmaceutical Technology and Biopharmacy  szilard.pal@aok.pte.hu
2 credit ▪ semester exam ▪ Pharm. theoretical module and practical skills subject ▪ autumn semester ▪ recommended semester: 7
Number of hours/semester:                         28 lectures + 0 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.):         1 – 80                  Prerequisites: see your Recommended Curriculum

Topic
Mainly semisolid dosage forms are prepared in this semester: suppositories and vaginal suppositories. Powders and capsules as solid
dosage forms are also prepared and discussed.
Conditions for acceptance of the semester
Code of Studies and Regulations
Mid-term exams
Students have to write three assessments during the semester and they have to reach 60 % after average calculation. After two assessments
if students reach average 60 % taking into account both tests, writing the third assesment it not compulsory. The third assessments (which
is considered as the 1st retake) has to above 60,1 %. If the student fails on the 3rd assessment, there is still chance for the 2nd retake,
where student has to reach 60,1% for the acceptance of the semester. In case of confirmed absence from the assessment, re-take chance
is sossible for the student. Missing the re-take results 0 % assessment.
Making up for missed classes
Students must fulfil requirements determined by the Code of Studies and Examinations.
Reading material
-   Obligatory literature
-   Literature developed by the Department
-   Notes
-   Recommended literature
    European Pharmacopoeia
    Formulae Normales VII. (FoNo VII.)
    James Swarbrick: Encyclopedia of Pharmaceutical Technology, Informa Healthcare, New York, London
    Gilbert S. Banker, Christopher T. Rhodes: Modern Pharmaceutics, Marcel Dekker Inc., New York- Basel
    Chris Langley, Dawn Belcher: Pharmaceutical Compounding and Dispensing, Pharmaceutical Press
    www.gytk.pte.hu
    www.sciencedirect.com
    Attila Dévay: The Theory and Practice of Pharmaceutical Technology, electronic book, PTE-Pécs
    Attila Dévay: Investigation of Pharmaceutical Preparations, electronic book, PTE-Pécs
Lectures
1       Crystallisation, polymorphism, and their technological aspects
        Dr. Secenji Aleksandar
2       Crystallisation, polymorphism, and their technological aspects
        Dr. Secenji Aleksandar
3       Drying, freeze-drying
        Dr. Secenji Aleksandar
4       Drying, freeze-drying
        Dr. Secenji Aleksandar
5       Grinding and shieving
        Dr. Pál Szilárd
6       Grinding and shieving
        Dr. Pál Szilárd
7       Preparation of granules I
        Dr. Pál Szilárd
8       Preparation of granules I
        Dr. Pál Szilárd
9       Preparation of granules II
        Dr. Pál Szilárd

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UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

10      Written test
        Dr. Pál Szilárd
11      Fluidization and its application
        Dr. Kása Péter
12      Fluidization and its application
        Dr. Kása Péter
13      Pharmaceutical excipients of granules
        Dr. Pál Szilárd
14      Pharmaceutical excipients of granules
        Dr. Pál Szilárd
15      Tabletting I
        Dr. Pál Szilárd
16      Tabletting I
        Dr. Pál Szilárd
17      Tabletting II (excipients, examinations)
        Dr. Pál Szilárd
18      Tabletting II (excipients, examinations)
        Dr. Pál Szilárd
19      Excipients for the preparation of tablets and granules
        Dr. Pál Szilárd
20      Written test
        Dr. Pál Szilárd
21      Coating of preparations
        Dr. Kása Péter
22      Coating of preparations
        Dr. Kása Péter
23      Pharmaceutical capsules
        Dr. Pál Szilárd
24      Pharmaceutical capsules
        Dr. Pál Szilárd
25      Written test
        Dr. Pál Szilárd
26      Written test
        Dr. Pál Szilárd
27      Inhaled drug delivery systems
        Dr. Kása Péter
28      Inhaled drug delivery systems
        Dr. Kása Péter
Practices
Seminars
Exam topics/questions
The end-semester exam will be evaluated by a five-grade system.
Knowledge acquired is tested based on subject matter defined by a list of topics provided by the institute.
At the end of semester, students take written exam. The date of "A" chance exam is in determined date for students finishing the course.
    Chance "B" and "C"are oral exams, which is preceded by the "Minimum Test" (MT). To write the MT, students have at most 30
    minutes, and will be evaluated percent rating. Those students, who achieve less than 60% in MT, unsatisfactory grade will be assessed
    and cannot pass them to the oral part of the exam.
Oral part includes two topics. In the case of any part done with insufficient knowledge, will result in assessment of the exam to
    unsatisfactory grade.
In addition to the exam topics, part of the exam is answering questions that aim at assessing the general knowledge of the student.
Participants

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UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

OPG-C3G-T              PHARMACEUTICAL TECHNOLOGY 3 - PRACTICE
Course director:                                                                                 DR. SZILÁRD PÁL, assistant professor
                                                      Institute of Pharmaceutical Technology and Biopharmacy  szilard.pal@aok.pte.hu
5 credit ▪ midsemester grade ▪ Pharm. theoretical module and practical skills subject ▪ autumn semester ▪ recommended semester: 7
Number of hours/semester:                          0 lectures + 70 practices + 0 seminars = total of 70 hours
Course headcount limitations (min.-max.):          1 – 80                  Prerequisites: see your Recommended Curriculum

Topic
Mainly semisolid dosage forms are prepared in this semester: suppositories and vaginal suppositories. Powders and capsules as solid
dosage forms are also prepared and discussed.
Conditions for acceptance of the semester
1. Accepted preparations made on practices.
2. Accepted work reports.
3. Accepted practical and theoretical assessments.
4. At the beginning of all practice classes students write short tests of different types (dose checking, synonim names and latin
expressions, calculations). Semester only can be accepted if students reach at least 50% from each short test type.
Mid-term exams
Students have to participate two practice tests.
Making up for missed classes
Students must fulfil requirements determined by the Code of Studies and Examinations.
All missed or failed preparations manufactured on the practice should be made up on supplementary practices!
Reading material
-   Obligatory literature
-   Literature developed by the Department
-   Notes
-   Recommended literature
    European Pharmacopoeia
    Formulae Normales VII. (FoNo VII.)
    James Swarbrick: Encyclopedia of Pharmaceutical Technology, Informa Healthcare, New York, London
    Gilbert S. Banker, Christopher T. Rhodes: Modern Pharmaceutics, Marcel Dekker Inc., New York- Basel
    Chris Langley, Dawn Belcher: Pharmaceutical Compounding and Dispensing, Pharmaceutical Press
    www.gytk.pte.hu
    www.sciencedirect.com
    Attila Dévay: The Theory and Practice of Pharmaceutical Technology, electronic book, PTE-Pécs
    Attila Dévay: Investigation of Pharmaceutical Preparations, electronic book, PTE-Pécs
Lectures
Practices
1       Sugar and film coating process
1       Sugar and film coating process
1       Sugar and film coating process
1       Sugar and film coating process
1       Sugar and film coating process
2       End semester assessment
2       End semester assessment
2       End semester assessment
2       End semester assessment
2       End semester assessment
3       General instructions, rules and regulations on practices, introduction to solid forms
3       General instructions, rules and regulations on practices, introduction to solid forms
3       General instructions, rules and regulations on practices, introduction to solid forms
3       General instructions, rules and regulations on practices, introduction to solid forms

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UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

3       General instructions, rules and regulations on practices, introduction to solid forms
4       Undivided (bulk) powders, dusting powders, species I
4       Undivided (bulk) powders, dusting powders, species I
4       Undivided (bulk) powders, dusting powders, species I
4       Undivided (bulk) powders, dusting powders, species I
4       Undivided (bulk) powders, dusting powders, species I
5       Undivided (bulk) powders, dusting powders, species II
5       Undivided (bulk) powders, dusting powders, species II
5       Undivided (bulk) powders, dusting powders, species II
5       Undivided (bulk) powders, dusting powders, species II
5       Undivided (bulk) powders, dusting powders, species II
6       Divided powders I
6       Divided powders I
6       Divided powders I
6       Divided powders I
6       Divided powders I
7       Divided powders II
7       Divided powders II
7       Divided powders II
7       Divided powders II
7       Divided powders II
8       Dusting powders
8       Dusting powders
8       Dusting powders
8       Dusting powders
8       Dusting powders
9       Pills, hard gelatin capsules
9       Pills, hard gelatin capsules
9       Pills, hard gelatin capsules
9       Pills, hard gelatin capsules
9       Pills, hard gelatin capsules
10      Assessment
10      Assessment
10      Assessment
10      Assessment
10      Assessment
11      Preparation of garnules I, drying
11      Preparation of garnules I, drying
11      Preparation of garnules I, drying
11      Preparation of garnules I, drying
11      Preparation of garnules I, drying
12      Preparation of garnules II, examinations
12      Preparation of garnules II, examinations
12      Preparation of garnules II, examinations
12      Preparation of garnules II, examinations
12      Preparation of garnules II, examinations
13      Tabletting I., Machines
13      Tabletting I., Machines
13      Tabletting I., Machines
13      Tabletting I., Machines
13      Tabletting I., Machines
14      Tabletting II., Direct compression
14      Tabletting II., Direct compression
14      Tabletting II., Direct compression
14      Tabletting II., Direct compression
14      Tabletting II., Direct compression

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UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

Seminars
Exam topics/questions
Website of the Institute.
Participants
Dr. Ferenczi Krisztina (I8U2DJ), Dr. Kása Péter (ISWPRM), Dr. Pál Szilárd (FYF5E9), Kopcsányi Márton (D3S7AX)

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UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

OPG-D1E-T              PHARMACODYNAMICS 1 - THEORY
Course director:                                                                                  DR. GÁBOR ISTVÁN PETHŐ, professor
                                                                                   Department of Pharmacology  gabor.petho@aok.pte.hu
2 credit ▪ semester exam ▪ Pharm. theoretical module and practical skills subject ▪ autumn semester ▪ recommended semester: 7
Number of hours/semester:                         28 lectures + 0 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.):         1 – 100                 Prerequisites: see your Recommended Curriculum

Topic
The aim of the course is to provide the students with the pharmacological knowledge required for their future work in the field of
pharmacy. Important topics are the general principles of pharmacodynamics and pharmacokinetics, pharmacology of the autonomic
nervous system and the cardiovascular system.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
There is no midterm exam/test.
Making up for missed classes
There is no way to make up for missed classes.
Reading material
-    Obligatory literature
-    Literature developed by the Department
     Electronic handouts are provided for most topics.
-    Notes
-    Recommended literature
     Rang, Dale, Ritter, Moore: Pharmacology, 9th edition, Elsevier Churchill Livingstone, 2019
     B. G. Katzung (ed.): Basic and Clinical Pharmacology, 14th edition, Lange Medical Books/McGraw-Hill, 2018
Lectures
1       Introduction to neuropharmacology. General characterization of the autonomic nervous system
        Dr. Barthó Loránd
2       Cholinergic agonists
        Dr. Barthó Loránd
3       Cholinesterase inhibitors I
        Dr. Barthó Loránd
4       Cholinesterase inhibitors II
        Dr. Barthó Loránd
5       Muscarinic receptor antagonists I
        Dr. Barthó Loránd
6       Muscarinic receptor antagonists II
        Dr. Barthó Loránd
7       Neuromuscular blocking agents I
        Dr. Pethő Gábor István
8       Neuromuscular blocking agents II
        Dr. Pethő Gábor István
9       Agents acting on biosynthesis, storage, release and elimination of catecholamines I
        Dr. Pethő Gábor István
10      Agents acting on biosynthesis, storage, release and elimination of catecholamines II
        Dr. Pethő Gábor István
11      Adrenergic receptor agonists I
        Dr. Pethő Gábor István
12      Adrenergic receptor agonists II
        Dr. Pethő Gábor István
13      Adrenergic receptor antagonists I
        Dr. Pethő Gábor István

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UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

14      Adrenergic receptor antagonists II
        Dr. Pethő Gábor István
15      Pharmacology of the calcium channels I
        Dr. Pethő Gábor István
16      Pharmacology of the calcium channels II
        Dr. Pethő Gábor István
17      Drugs acting on the renin-angiotensin-aldosterone system I
        Dr. Poór Miklós
18      Drugs acting on the renin-angiotensin-aldosterone system II
        Dr. Poór Miklós
19      Diuretic drugs I
        Dr. Pethő Gábor István
20      Diuretic drugs II
        Dr. Pethő Gábor István
21      Drugs used for treating congestive heart failure I
        Dr. Börzsei Rita Judit
22      Drugs used for treating congestive heart failure II
        Dr. Börzsei Rita Judit
23      Antiarrhythmic drugs I
        Dr. Pethő Gábor István
24      Antiarrhythmic drugs II
        Dr. Pethő Gábor István
25      Antianginal drugs I
        Dr. Pethő Gábor István
26      Antianginal drugs II. Drugs increasing regional blood flow
        Dr. Pethő Gábor István
27      Antihypertensive drugs I
        Dr. Pethő Gábor István
28      Antihypertensive drugs II
        Dr. Pethő Gábor István
Practices
Seminars
Exam topics/questions
Reqirements: the exams are oral, the required topics are dealt with during the semester lectures and practical classes. The criterion of
   admission to the exam is the successful completion of the Pharmacodynamics 1 practice course carried out in paralell (at least
   satisfactory midsemester grade).

Exam questions:
1. Basic mechanisms of drug actions
2. Characterization of agonist-receptor interaction: occupancy, affinity, dose-response curve, potency, efficacy
3. Significance of signal transduction mechanisms in the effects of drugs. Tachyphylaxis and tolerance to drugs
4. Mechanisms of drug antagonisms
5. Transport of drugs across membranes
6. Absorption of drugs, oral bioavailability and presystemic elimination
7. Distribution of drugs
8. Biotransformation of drugs
9. Excretion of drugs
10. Pharmacokinetics: zero and first order elimination, volume of distribution, clearance, elimination half-life, oral bioavailability,
    calculation of loading and maintenance doses
11. Cholinergic agonists and cholinesterase inhibitors
12. Muscarinic receptor antagonists
13. Neuromuscular blocking agents. Drugs acting on autonomic ganglia
14. Agents acting on the biosynthesis, storage, release and elimination of catecholamines
15. Adrenergic receptor agonists
16. Adrenergic receptor antagonists
17. Local anaesthetics
18. Calcium channel blockers
19. Drugs acting on the renin-angiotensin-aldosterone system

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UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

20. Diuretic drugs
21. Positive inotropic and other drugs used to treat congestive heart failure
22. Antianginal drugs. Drugs that increase regional blood flow
23. Antihypertensive drugs
24. Antiarrhythmic drug

In addition to the exam topics, an important part of the exam is answering questions that aim at assessing the general knowledge of the
    student.
Participants

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UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

OPG-D1G-T              PHARMACODYNAMICS 1 - PRACTICE
Course director:                                                                                  DR. GÁBOR ISTVÁN PETHŐ, professor
                                                                                   Department of Pharmacology  gabor.petho@aok.pte.hu
2 credit ▪ midsemester grade ▪ Pharm. theoretical module and practical skills subject ▪ autumn semester ▪ recommended semester: 7
Number of hours/semester:                          0 lectures + 28 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.):          1 – 100                 Prerequisites: see your Recommended Curriculum

Topic
The aim of the course is to provide the students with the pharmacological knowledge required for their future work in the field of
pharmacy. Important topics are the general principles of pharmacodynamics and pharmacokinetics.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
The students receive a practice grade based on their performance during the semester. The grade will be registered in the Neptun as a
midsemester grade. The grade must be at least satisfactory as a prerequisite for taking the semester exam. Around the 11th week of the
semester, a written test is the base of the practice grade. The test covers the subjects of practice classes of the first 10 weeks of the
semester and 50% of the available points must be reached for acceptance of the semester. Should someone fail or want to improve, they
can do it one time before the end of the semester. On a final failure (that is, after the improvement attempt still below 50%), the student
cannot have semester accepted.
Making up for missed classes
There is no way to make up for missed classes.
Reading material
-    Obligatory literature
-    Literature developed by the Department
     Electronic handouts are provided for most topics.
-    Notes
-    Recommended literature
     Rang, Dale, Ritter, Moore: Pharmacology, 9th edition, Elsevier Churchill Livingstone, 2019
     B. G. Katzung (ed.): Basic and Clinical Pharmacology, 14th edition, Lange Medical Books/McGraw-Hill, 2018
Lectures
Practices
1       Introduction to pharmacodynamics I.
        Dr. Pethő Gábor István
2       Introduction to pharmacodynamics II.
        Dr. Pethő Gábor István
3       Basic mechanisms of drug actions
        Dr. Faisal Anna Zelma
4       Characterization of the agonist-receptor interaction I.
        Dr. Faisal Anna Zelma
5       Characterization of the agonist-receptor interaction II.
        Hartnerné Dr. Pohóczky Krisztina
6       Characterization of the agonist-receptor interaction III.
        Hartnerné Dr. Pohóczky Krisztina
7       Signal transduction mechanisms of drug receptors
        Dr. Mohos Violetta Karolin
8       Tachyphylaxis and tolerance
        Dr. Mohos Violetta Karolin
9       Mechanisms of drug antagonisms I.
        Hartnerné Dr. Pohóczky Krisztina
10      Mechanisms of drug antagonisms II.
        Hartnerné Dr. Pohóczky Krisztina
11      Transport of drugs across membranes
        Dr. Fliszár-Nyúl Eszter

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UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

12      Absorption of drugs I.
        Dr. Fliszár-Nyúl Eszter
13      Absorption of drugs II. Binding of drugs to plasma proteins
        Dr. Poór Miklós
14      Distribution of drugs
        Dr. Poór Miklós
15      Biotransformation of drugs I.
        Dr. Poór Miklós
16      Biotransformation of drugs II.
        Dr. Poór Miklós
17      Biotransformation of drugs III.
        Dr. Poór Miklós
18      Excretion of drugs
        Dr. Poór Miklós
19      Pharmacokinetic parameters I.
        Dr. Fliszár-Nyúl Eszter
20      Pharmacokinetic parameters II.
        Dr. Fliszár-Nyúl Eszter
21      Local anesthetics I.
        Dr. Pethő Gábor István
22      Local anesthetics II.
        Dr. Pethő Gábor István
23      Drugs acting on autonomic ganglia
        Dr. Pethő Gábor István
24      Theoretical basis of the modulation of the pharmacology of the automatic nervous system
        Dr. Pethő Gábor István
25      Discussion of the pharmacology of the parasympathetic nervous system I.
        Dr. Barthó Loránd
26      Discussion of the pharmacology of the parasympathetic nervous system II.
        Dr. Barthó Loránd
27      Discussion of the pharmacology of the sympathetic nervous system I.
        Dr. Barthó Loránd
28      Discussion of the pharmacology of the sympathetic nervous system II.
        Dr. Barthó Loránd
Seminars
Exam topics/questions
1. Basic mechanisms of drug actions
2. Characterization of agonist-receptor interaction: occupancy, affinity, dose-response curve, potency, efficacy
3. Significance of signal transduction mechanisms in the effects of drugs. Tachyphylaxis and tolerance to drugs
4. Mechanisms of drug antagonisms
5. Transport of drugs across membranes
6. Absorption of drugs, oral bioavailability and presystemic elimination
7. Distribution of drugs
8. Biotransformation of drugs
9. Excretion of drugs
10. Pharmacokinetics: zero and first order elimination, volume of distribution, clearance, elimination half-life, oral bioavailability,
    calculation of loading and maintenance doses
Participants
Dr. Barthó Loránd (DK1RNK), Dr. Faisal Anna Zelma (KVG5NA), Dr. Fliszár-Nyúl Eszter (TUOYWS), Dr. Mohos Violetta Karolin
(K9WTSC), Dr. Pethő Gábor István (F2YVEE), Dr. Poór Miklós (ARWF5Z), Hartnerné Dr. Pohóczky Krisztina (OX02SO)

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UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

OPG-GAI-T              PHARMACEUTICAL APPLIED IMMUNOLOGY
Course director:                                                                        DR. JUDIT ERZSÉBET PONGRÁCZ, professor
                                                                 Department of Pharmaceutical Biotechnology  pongracz.e.judit@pte.hu
2 credit ▪ semester exam ▪ Pharm. theoretical module and practical skills subject ▪ autumn semester ▪ recommended semester: 7
Number of hours/semester:                         14 lectures + 0 practices + 14 seminars = total of 28 hours
Course headcount limitations (min.-max.):         5 – 50                  Prerequisites: see your Recommended Curriculum

Topic
Immunology from a pharmaceutical aspect. The course material is designed to provide theoretical background to the effects of currently
employed drugs on the immune system. The course will discuss the latest advances in understanding of immune cells after treatment
with various medicines including antimicrobials, cancer drugs, etc. and how these drugs modify the immune response to aid or inhibit
recovery from a particular disease.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Written test
Making up for missed classes
According to the Code of Studies and Examinations.
Reading material
-    Obligatory literature
-    Literature developed by the Department
     Lecture and seminar ppt
-    Notes
     Lecture notes, learning materials of the lectures are available on MeetStreet
     Pharmaceutical Applied Immunology 2019
-    Recommended literature
Lectures
1        Immunology: a pharmaceutical perspective – Immune effects of drugs acting on the nervous system
         Dr. Pongrácz Judit Erzsébet
2        Bacterial infection – Effects of antibiotics on the immune system
         Dr. Pongrácz Judit Erzsébet
3        Viral infection I. – Effects of antiviral drugs on the immune system
         Dr. Pongrácz Judit Erzsébet
4        Viral infection II. – Effects of antiviral drugs on the immune system
         Dr. Pongrácz Judit Erzsébet
5        Parasite infection – Effects of anti-parasitic drugs on the immune system
         Dr. Pongrácz Judit Erzsébet
6        Fungal infection – Effects of antifungal drugs on the immune system
         Dr. Pongrácz Judit Erzsébet
7        Vitamins and the immune system – Effects of vitamins on the immune system
         Dr. Pongrácz Judit Erzsébet
8        Tumors and immunotherapy – Effects of chemotherapy on the immune system
         Dr. Pongrácz Judit Erzsébet
9        Tumors and immunotherapy – Immunological agents used in cancer therapy and their effects on the immune system
         Dr. Pongrácz Judit Erzsébet
10       Hypersensitive reactions I. – Immune effects of drugs used in the therapy of hypersensitivity reactions
         Dr. Pongrácz Judit Erzsébet
11       Hypersensitive reactions II. – Immune effects of drugs used in the therapy of hypersensitivity reactions
         Dr. Pongrácz Judit Erzsébet
12       Vaccination – Effects of vaccines on the immune system
         Dr. Pongrácz Judit Erzsébet
13       Novel therapies using the immune system
         Dr. Pongrácz Judit Erzsébet

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UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

14      Personalized therapies
        Dr. Pongrácz Judit Erzsébet
Practices
Seminars
1       Immune effects of drugs acting on the nervous system
        Elhusseiny Mohamed Mahmoud
2       Effects of antibiotics on the immune system
        Elhusseiny Mohamed Mahmoud
3       Effects of antiviral drugs on the immune system I
        Elhusseiny Mohamed Mahmoud
4       Effects of antiviral drugs on the immune system II
        Elhusseiny Mohamed Mahmoud
5       Effects of anti-parasitic drugs on the immune system
        Elhusseiny Mohamed Mahmoud
6       Fungal infection – Effects of antifungal drugs on the immune system
        Elhusseiny Mohamed Mahmoud
7       Effects of vitamins on the immune system
        Elhusseiny Mohamed Mahmoud
8       Effects of chemotherapy on the immune system
        Elhusseiny Mohamed Mahmoud
9       Immunological agents used in cancer therapy and their effects on the immune system
        Elhusseiny Mohamed Mahmoud
10      Immune effects of drugs used in the therapy of hypersensitivity reactions I
        Elhusseiny Mohamed Mahmoud
11      Immune effects of drugs used in the therapy of hypersensitivity reactions II
        Elhusseiny Mohamed Mahmoud
12      Effects of vaccines on the immune system
        Elhusseiny Mohamed Mahmoud
13      Novel therapies using the immune system
        Elhusseiny Mohamed Mahmoud
14      Personalized therapies
        Elhusseiny Mohamed Mahmoud
Exam topics/questions
MeetStreet
Participants
Abdelwahab Elhusseiny Mohamed Mahmoud (ZYY8OB)

                                                                       14
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

OPG-GI2-T              PHARMACEUTICAL PRACTICE AND MANAGEMENT 1
Course director:                                                                                         DR. LAJOS BOTZ, professor
                                                             Department of Pharmaceutics and University Pharmacy  botz.lajos@pte.hu
3 credit ▪ semester exam ▪ Pharm. theoretical module and practical skills subject ▪ autumn semester ▪ recommended semester: 7
Number of hours/semester:                         28 lectures + 0 practices + 14 seminars = total of 42 hours
Course headcount limitations (min.-max.):         5 – 50                  Prerequisites: see your Recommended Curriculum

Topic
The topics of the semester introduce the basic functioning of the pharmaceutical and health-care market, further the basic fundamentals
of economics relevant for pharmacy students. Methods of comprehensive analysis, evaluation and development of drug therapy,
healthcare systems, the framework and regulation of pharmaceutical supply will be covered throughout the semester. Interactive
discussions will cover essential topics regarding self-medication and over the counter products used in minor diseases. Students will
improve their communicational skills in order to counsel patients more efficiently and improve adherence to medications. The
undergraduates will acquire knowledge of the innovation of a new drug from a drug candidate, the formation of indications, marketing
authorization, the life cycle of medicines and generics, as well as professional aspects of medication errors and adverse event.
Students can access the slides of the lectures and further reading material on a designated web based interface (e.g. MS Teams and/or
Neptun Meet Street).
Conditions for acceptance of the semester
-           Regular attendance of classes (maximum 25 % of absence is accepted),
-           Assignments given in class should be carried out during term-time and,
-         Written mid-term and end-of-the term test. Passing the tests is not obligatory; however advisable as you will likely have better
results and a good recommended grade for PPM1.There is a retake opportunity only for the end-of-the term test.
Mid-term exams
End-of-the-term test is at the regular time of lectures.
The test will be on the whole semester’s curriculum. Additional questions can be included in the end-of-the-term test, if the student has
not carried out an assignment during the semester or in case of unsuccessful midterm test.
In case of unsuccessful or missed end-of-the term test, a retake opportunity is granted to make up during the last week of the semester.
The end-of-the term test grade may be accepted as an examination grade, if passed.
Making up for missed classes
Retake opportunity is possible following personal discussion for the end-of-the term test.
Reading material
-   Obligatory literature
-   Literature developed by the Department
    List of study aids to acquire curriculum (books, notes, other) and all presentations can be downloaded from MS Teams and/or Neptun
    MeetStreet.
-   Notes
-   Recommended literature
    J.L. Bootman, R. J. Townsend, W. F. McGhan (eds.): Principles of Pharmacoeconomics, Harvey Whitney Book Company, 2002.
    Robert S. Beardsley, Carole L. Kimberlin, William N. Tindall: Communication Skills in Pharmacy Practice, 6th edition, Wolters
    Kluwer, Lipincott Williams & Wilkins, 2012.
    Rosemary R. Berardi, Stefanie P. Ferreri et al.: Handbook of Nonpresciption Drugs, 17th edition, American Pharmacists Association, 2012.
    John P. Griffin, John Posner, Geoffrey R. Barker: The Textbook of Pharmaceutical Medicine, 7th Edition, 2013.
    Paul Rutter: Community Pharmacy - Symptoms, Diagnosis and Treatment. 4th Edition Elsevier 2017.
Lectures
1       Drug authorization process, Patent of drugs 1
        Dr. Miseta Ildikó
2       Drug authorization process, Patent of drugs 2
        Dr. Miseta Ildikó
3       Variations of authorization processes (orphan drugs, generic, etc.)
        Dr. Miseta Ildikó
4       Drug Research and Development
        Dr. Vida Róbert György

                                                                       15
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

5       Nonclinical studies, preclinical development, Design and methodology in clinical trials
        Dr. Vida Róbert György
6       Clinical trials 1
        Dr. Vida Róbert György
7       Clinical trials 2
        Dr. Vida Róbert György
8       The drug supply chain, participants of the drug market 1.
        Dr. Fittler András Tamás
9       The drug supply chain, participants of the drug market 2.
        Dr. Fittler András Tamás
10      Prescribing and reimbursement of medicines in Hungary 1.
        Dr. Fittler András Tamás
11      Prescribing and reimbursement of medicines in Hungary 2.
        Dr. Fittler András Tamás
12      Equivalencies of drugs 1
        Dr. Miseta Ildikó
13      Equivalencies of drugs 2
        Dr. Miseta Ildikó
14      Midterm test
        Dr. Vida Róbert György
15      Pharmacovigilance 1
        Dr. Fittler András Tamás
16      Pharmacovigilance 2
        Dr. Fittler András Tamás
17      Organisation of Hungarian health system
        Dr. Vida Róbert György
18      Principles and basic terms of economics
        Dr. Fittler András Tamás
19      Requirements of opening and operation of pharmacies. Regulation of public drug supply.
        Dr. Vida Róbert György
20      Market mechanisms. Economic actors, sectors of economy.
        Dr. Fittler András Tamás
21      Perfect market and health market 1.
        Dr. Fittler András Tamás
22      Perfect market and health market 2.
        Dr. Fittler András Tamás
23      Social insurance, healthcare systems.
        Dr. Bella Richárd
24      Regulation regarding prescribing and dispensing of medicines in Hungary. Limitation of distribution of medicines in the EU.
        Dr. Fittler András Tamás
25      Requirements of opening and operation of pharmacies. Regulation of public drug supply
        Dr. Fittler András Tamás
26      End-of-the term test
        Dr. Fittler András Tamás
27      End-of-the term test
        Dr. Vida Róbert György
28      End-of-the term test
        Dr. Fittler András Tamás
Practices
Seminars
1       Basics of communication. Importance of good communication in pharmacy.
        Dr. Fittler András Tamás
2       Steps of good communication 1.
        Dr. Miseta Ildikó
3       Steps of good communication 2.
        Dr. Miseta Ildikó
4       Written communication, oral presentation.
        Dr. Fittler András Tamás

                                                                       16
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

5       Introduction - self-care, legal issues.
        Dr. Fittler András Tamás
6       Introduction - patient assessment and consultation.
        Dr. Fittler András Tamás
7       Midterm test
        Dr. Fittler András Tamás
8       Sample presentation, PowerPoint presentation scheme.
        Dr. Fittler András Tamás
9       Nutrition, mineral replacement and vitamins.
        Dr. Bella Richárd
10      Dry skin, atopic dermatitis, acne.
        Dr. Somogyi-Végh Anna
11      Smoking cessation.
        Dr. Somogyi-Végh Anna
12      Minor burns, wounds.
        Dr. Bella Richárd
13      Simulation of a small, pilot clinical study.
        Dr. Fittler András Tamás
14      End-of-the term test
        Dr. Bella Richárd
Exam topics/questions
Assessment of the student performance is carried out according to a five-grade scale:100-86,1% -excellent (5); 86-77,1% -good (4); 77-
    68,1% -satisfactory (3); 68-60,1% -pass (2); and below 60,0% -fail (1) respectively.
Final recommended grade for PPM1 is based upon the completion of the given assignments, self-care and nonprescription
    pharmacotherapy module, the mid-term test and the end-of-the term test. There is no practical grade for PPM1.
Participants
Dr. Bella Richárd (IL65ZJ), Dr. Fittler András Tamás (IYR5HQ), Dr. Miseta Ildikó (B743LU), Dr. Somogyi-Végh Anna (CPFSLI)

                                                                       17
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

OPG-PPA-T              PHARMACEUTICAL PATHOLOGY
Course director:                                                                                              DR. LIVIA VIDA, specialist
                                                                                              Department of Pathology  vida.livia@pte.hu
1 credit ▪ semester exam ▪ Pharm. theoretical module and practical skills subject ▪ autumn semester ▪ recommended semester: 7
Number of hours/semester:                         14 lectures + 0 practices + 0 seminars = total of 14 hours
Course headcount limitations (min.-max.):         5 – 100                 Prerequisites: see your Recommended Curriculum

Topic
Our course is devoted to interpret the patholgic basis of diseases to pharmacist undergraduates. Our aim is to present the study of the
structural, biochemical, and functional changes in cells, tissues and organs that underlie diseases. By the use of molecular, microand
macromorphologic techniques, pathology attempts to provide diagnosis and a rational basis for clinical care and therapy, placing special
emphasis on pharmacotherapeutic aspects. Pathology serves as the bridge between the basic sciences and clinical studies and is the
scientific foundation for the entirety of the medicine.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Students will have two midterm exams (around week 7 and 14). The final grade is calculated as the arithmetic average of the two
midterms' results.
Making up for missed classes
There is no opportunity to make up missed classes.
Reading material
-    Obligatory literature
-    Literature developed by the Department
     Lecture handouts are provided. Recorded lectures in mp4 format are also available.
-    Notes
-    Recommended literature
     Robbins Basic Pathology, 10th Edition.
Lectures
1       Disease types in the human body. Necrosis. Acute and chronic inflammation. Oncology basic concepts.
        Dr. Vida Livia
2       Disease types in the human body. Thronbosis and embolisation. Pathology of the immune system.
        Dr. Vida Livia
3       Cardiovascular diseases I. Heart diseases. Disease of arteries and veins.
        Dr. Vida Livia
4       Cardiovascular diseases II. High blood pressure. Valvular diseases. Developmental malformations.
        Dr. Vida Livia
5       Diseases of the respiratory system I. Upper and lower airway infections. Asthma. Acute lung injury.
        Dr. Vida Livia
6       Diseases of the respiratory system II. COPD. Pneumoconioses. Laryngeal and lung cancer.
        Dr. Vida Livia
7       Diseases of the liver and the biliary system. Liver failure. Hepatitides. Cholelithiasis. Pancreatitis. Malignant diseases.
        Dr. Vida Livia
8       Diseases of the kidney and the male genitalia. Glomerulonephritides. Pyelonephritides. Kidney stones. Diseases of the testis and
        the prostate. Malignant diseases.
        Dr. Kaszás Bálint
9       Diseases of the gastrointestinal tract I. Diseases of the oral cavity, the esophagus and the stomach.
        Dr. Kaszás Bálint
10      Diseases of the gastrointestinal tract II. Diseases of the small and the large intestine.
        Dr. Kaszás Bálint
11      Diseases of the hemopoetic system. Anemias. Hodgkin lymphoma. Non-hodgkin lymphomas. Acute leukaemias.
        Dr. Kaszás Bálint
12      Diseases of the endocrine system. Pituitary, thyroid and adrenal gland diseases.
        Dr. Kaszás Bálint

                                                                       18
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

13      Diseases of the central nervous system. Circulatory dysturbances. Dementias. Infections. Demyelinisating and malignant
        diseases.
        Dr. Kaszás Bálint
14      Diseases of the female genital tract. Breast cancer. Cervical cancer. Endometriosis.
        Dr. Kaszás Bálint
Practices
Seminars
Exam topics/questions
Disease types in the human body.
Cardiovascular diseases.
Diseases of the respiratory system.
Diseases of the liver and the biliary system.
Diseases of the kidney and the male genitalia.
Diseases of the gastrointestinal tract.
Diseases of the hemopoetic system.
Diseases of the endocrine system.
Diseases of the central nervous system.
Diseases of the female genital tract.
Participants

                                                                       19
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

OPG-R3E-T              PHARMACEUTICAL CHEMISTRY 3 - THEORY
Course director:                                                                        DR. ZSUZSANNA ROZMER, assistant professor
                                                                    Department of Pharmaceutical Chemistry  rozmer.zsuzsanna@pte.hu
3 credit ▪ semester exam ▪ Pharm. theoretical module and practical skills subject ▪ autumn semester ▪ recommended semester: 7
Number of hours/semester:                         42 lectures + 0 practices + 0 seminars = total of 42 hours
Course headcount limitations (min.-max.):         5 – 50                  Prerequisites: see your Recommended Curriculum

Topic
Introduction to molecular aspect, structure-activity relationship and pharmacopoeal qualification of selected group of active
pharmaceutical ingredients. Basic principles and application of the analytical methods most frequently used in the pharmacopoeal
qualifications.
Conditions for acceptance of the semester
Acknowledgement of the course is in accord with the Code of Studies and Examinations. Participation is both the lectures and the
practices is obligatory. Maximum three absences can be accepted both from lectures and practices. Students have to write two midterm
tests (week 7. and 12.) from the topics of the theory and the practice. One of the test result should be above 60%, the average of the tests
should be above 50%. One re-take test is allowed at the 14th weak of the semester. Students have to write at least four mini-tests on the
practices. The average of the results must be at least 50%. The practical work (results of the written tests and the experimental work) is
evaluated by a practical grade. Satisfactory (2) evaluation is the minimum requirement of acknowledgement of the semester.
Mid-term exams
Students have to write two midterm tests (week 7. and 12.) from the topics of the theory and the practice. One of the test result should be
above 60%, the average of the tests should be above 50%. One re-take test is allowed at the 14th weak of the semester. Students have to
write at least four mini-tests on the practices. The average of the results must be at least 50%. The practical work (results of the written
tests and the experimental work) is evaluated by a practical grade. Satisfactory (2) evaluation is the minimum requirement of
acknowledgement of the semester.
Making up for missed classes
There is no opportunity to make up missed classes.
Reading material
-   Obligatory literature
    D.A. Williams, T.L. Lemke (eds.): Foye's Principles of Medicinal Chemistry, 7th edition, Lippincott Williams & Wilkins,
    Philadelphia, 2013
-   Literature developed by the Department
    Attila Almási, Zsuzsanna Rozmer, Pál Perjési: Pharmaceutical Chemistry 1. Laboratory Experiments and Commentary, electronic
    educational material, PTE 2014
-   Notes
-   Recommended literature
    European Pharmacopoeia, EDQM Publication
    Lecture notes.
Lectures
1       Application of CD and ORD spectroscopy in pharmaceutical analysis.
        Dr. Perjési Pál
2       Application of UV-Vis spectroscopy in pharmaceutical analysis
        Dr. Perjési Pál
3       Application of UV-Vis spectroscopy in pharmaceutical analysis.
        Dr. Perjési Pál
4       Application of thermoanalytic methods in pharmaceutical analysis.
        Dr. Kulcsár Győző Kornél
5       Application of fluorimetry in pharmaceutical analysis.
        Dr. Perjési Pál
6       Application of fluorimetry in pharmaceutical analysis.
        Dr. Perjési Pál
7       Application of atomic absorption spectrometry and flame photometry in pharmaceutical analysis.
        Dr. Kulcsár Győző Kornél
8       Application of IR spectroscopy in pharmaceutical analysis.
        Dr. Lóránd Tamás

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UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

9       Application of IR spectroscopy in pharmaceutical analysis.
        Dr. Lóránd Tamás
10      Biological drugs I.
        Dr. Rozmer Zsuzsanna
11      Application of NMR spectroscopy in pharmaceutical analysis.
        Dr. Perjési Pál
12      Application of NMR spectroscopy in pharmaceutical analysis.
        Dr. Perjési Pál
13      Biological drugs II.
        Dr. Rozmer Zsuzsanna
14      Application of mass spectrometry in pharmaceutical analysis.
        Dr. Kulcsár Győző Kornél
15      Application of mass spectrometry in pharmaceutical analysis.
        Dr. Kulcsár Győző Kornél
16      Antiallergic antihistamines. Drugs for rheumatic gout I.
        Dr. Rozmer Zsuzsanna
17      Application of electroanalytical methods in pharmaceutical analysis.
        Dr. Perjési Pál
18      Application of electroanalytical methods in pharmaceutical analysis.
        Dr. Perjési Pál
19      Antiallegic antihistamines. Drugs for rheumatic gout II.
        Dr. Rozmer Zsuzsanna
20      Agents of cardiac failure.
        Dr. Perjési Pál
21      Agents of cardiac failure.
        Dr. Perjési Pál
22      Antianginal drugs.
        Dr. Rozmer Zsuzsanna
23      Agents of antiarythmic agents.
        Dr. Almási Attila
24      Agents of antiarythmic agents.
        Dr. Almási Attila
25      Antithrombotics, Thrombolytics, Coagulants I.
        Dr. Rozmer Zsuzsanna
26      Antihipertensive agents.
        Dr. Almási Attila
27      Antihipertensive agents.
        Dr. Almási Attila
28      Antithrombotics, Thrombolytics, Coagulants II.
        Dr. Rozmer Zsuzsanna
29      Antihiperlidemic agents.
        Dr. Rozmer Zsuzsanna
30      Antihiperlidemic agents.
        Dr. Rozmer Zsuzsanna
31      Drugs affecting thyroid functions.
        Dr. Almási Attila
32      Diuretics.
        Dr. Almási Attila
33      Diuretics.
        Dr. Almási Attila
34      Adrenocorticoids I.
        Dr. Perjési Pál
35      Drugs affecting calcium homeostatis.
        Dr. Rozmer Zsuzsanna
36      Drugs affecting calcium homeostatis.
        Dr. Rozmer Zsuzsanna
37      Adrenocorticoids II.
        Dr. Perjési Pál

                                                                       21
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

38      Insulin and oral hypoglycemic drugs.
        Dr. Almási Attila
39      Insulin and oral hypoglycemic drugs.
        Dr. Almási Attila
40      Estrogens, Androgens, Progestins I.
        Dr. Perjési Pál
41      Estrogens, Androgens, Progestins II.
        Dr. Perjési Pál
42      Estrogens, Androgens, Progestins II.
        Dr. Perjési Pál
Practices
Seminars
Exam topics/questions
Written exam covering the topics of the lectures and the laboratory practices. The result of the written exam must be above 60%. The
   final grade is based on results of the midterm tests and the written exam. Maximum contribution of the results of the midterm tests
   to the total score of the written exam is 25%. Participation on the first exam is compulsory.
Participants

                                                                       22
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

OPG-R3G-T              PHARMACEUTICAL CHEMISTRY 3 - PRACTICE
Course director:                                                                        DR. ZSUZSANNA ROZMER, assistant professor
                                                                    Department of Pharmaceutical Chemistry  rozmer.zsuzsanna@pte.hu
4 credit ▪ midsemester grade ▪ Pharm. theoretical module and practical skills subject ▪ autumn semester ▪ recommended semester: 7
Number of hours/semester:                          0 lectures + 56 practices + 0 seminars = total of 56 hours
Course headcount limitations (min.-max.):          5 – 50                  Prerequisites: see your Recommended Curriculum

Topic
Introduction to the most important instrumental analytical methods and their applications to pharmacopoeal qualification of active
pharmaceutical ingredients and excipients in pharamaceutical formulations.
Conditions for acceptance of the semester
Acknowledgement of the course is in accord with the Code of Studies and Examinations. Participation in the practices is obligatory.
Maximum three absences can be accepted. Students have to write at least four short tests on the practices. The average of the results must
be at least 50%. The practical work (results of the written tests and the experimental work) is evaluated by a practice grade.
Mid-term exams
Students have to write at least four short tests on the practices. The average of the results must be at least 50%. The practical work (results
of the written tests and the experimental work) is evaluated by a practice grade.
Making up for missed classes
There is no opportunity to make up missed classes.
Reading material
-    Obligatory literature
     D.A. Williams, T.L. Lemke (eds.): Foye's Principles of Medicinal Chemistry, 7th edition, Lippincott Williams & Wilkins,
     Philadelphia, 2013
-    Literature developed by the Department
     Attila Almási, Zsuzsanna Rozmer, Pál Perjési: Pharmaceutical Chemistry 1. Laboratory Experiments and Commentary, electronic
     educational material, PTE 2014
-    Notes
     Pharmaceutical Chemistry Practice 1, laboratory manual, University of Pécs, 2015
-    Recommended literature
     European Pharmacopoeia, EDQM Publication
     Lecture notes.
Lectures
Practices
1       Laboratory safety and accident protection. Preliminary         testing and classification of inorganic and organic compounds I.
        Identification of 10 inorganic and organic substances I.
2       Laboratory safety and accident protection. Preliminary         testing and classification of inorganic and organic compounds I.
        Identification of 10 inorganic and organic substances I.
3       Laboratory safety and accident protection. Preliminary         testing and classification of inorganic and organic compounds I.
        Identification of 10 inorganic and organic substances I.
4       Laboratory safety and accident protection. Preliminary         testing and classification of inorganic and organic compounds I.
        Identification of 10 inorganic and organic substances I.
5       Preliminary testing and classification of inorganic and        organic compounds II. Identification of 10 inorganic and organic
        substances II.
6       Preliminary testing and classification of inorganic and        organic compounds II. Identification of 10 inorganic and organic
        substances II.
7       Preliminary testing and classification of inorganic and        organic compounds II. Identification of 10 inorganic and organic
        substances II.
8       Preliminary testing and classification of inorganic and        organic compounds II. Identification of 10 inorganic and organic
        substances II.
9       Principles of validation of analytical methods. (Seminars)
10      Principles of validation of analytical methods. (Seminars)
11      Principles of validation of analytical methods. (Seminars)
12      Principles of validation of analytical methods. (Seminars)

                                                                       23
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022

13      Validation of a titrimetric methods. Comparison of different methods, Determination of sodium hydrogen carbonate according
        to the Ph. Hg. VII. and the Ph. Hg. VIII.
14      Validation of a titrimetric methods. Comparison of different methods, Determination of sodium hydrogen carbonate according
        to the Ph. Hg. VII. and the Ph. Hg. VIII.
15      Validation of a titrimetric methods. Comparison of different methods, Determination of sodium hydrogen carbonate according
        to the Ph. Hg. VII. and the Ph. Hg. VIII.
16      Validation of a titrimetric methods. Comparison of different methods, Determination of sodium hydrogen carbonate according
        to the Ph. Hg. VII. and the Ph. Hg. VIII.
17      Spectrophotometry I. The Lambert-Beer's law. Determination of specific absorbance. Spectrophotometric determination of
        coffein, aminophenazone and paracetamol in powder mixtures.
18      Spectrophotometry I. The Lambert-Beer's law. Determination of specific absorbance. Spectrophotometric determination of
        coffein, aminophenazone and paracetamol in powder mixtures.
19      Spectrophotometry I. The Lambert-Beer's law. Determination of specific absorbance. Spectrophotometric determination of
        coffein, aminophenazone and paracetamol in powder mixtures.
20      Spectrophotometry I. The Lambert-Beer's law. Determination of specific absorbance. Spectrophotometric determination of
        coffein, aminophenazone and paracetamol in powder mixtures.
21      Spectrophotometry II. Determination of salicylic acid and acetylsalicylic acid in mixtures by spectrophotometric and alkalimetric
        methods.
22      Spectrophotometry II. Determination of salicylic acid and acetylsalicylic acid in mixtures by spectrophotometric and alkalimetric
        methods.
23      Spectrophotometry II. Determination of salicylic acid and acetylsalicylic acid in mixtures by spectrophotometric and alkalimetric
        methods.
24      Spectrophotometry II. Determination of salicylic acid and acetylsalicylic acid in mixtures by spectrophotometric and alkalimetric
        methods.
25      Application of fluometric methods. Application of NMR in pharmaceutical analysis. Principles of evaluation of NMR spectra.
        Evaluation of 1H and 13C NMR spectra of selected drug substances. (Seminar)
26      Application of fluometric methods. Application of NMR in pharmaceutical analysis. Principles of evaluation of NMR spectra.
        Evaluation of 1H and 13C NMR spectra of selected drug substances. (Seminar)
27      Application of fluometric methods. Application of NMR in pharmaceutical analysis. Principles of evaluation of NMR spectra.
        Evaluation of 1H and 13C NMR spectra of selected drug substances. (Seminar)
28      Application of fluometric methods. Application of NMR in pharmaceutical analysis. Principles of evaluation of NMR spectra.
        Evaluation of 1H and 13C NMR spectra of selected drug substances. (Seminar)
29      Application of IR in pharmaceutical analysis. Principles of evaluation of IR spectra. Evaluation of IR spectra of selected drug
        substances. (Seminar) Application of mass spectrometry methods.
30      Application of IR in pharmaceutical analysis. Principles of evaluation of IR spectra. Evaluation of IR spectra of selected drug
        substances. (Seminar) Application of mass spectrometry methods.
31      Application of IR in pharmaceutical analysis. Principles of evaluation of IR spectra. Evaluation of IR spectra of selected drug
        substances. (Seminar) Application of mass spectrometry methods.
32      Application of IR in pharmaceutical analysis. Principles of evaluation of IR spectra. Evaluation of IR spectra of selected drug
        substances. (Seminar) Application of mass spectrometry methods.
33      Application of electroanalytical methods in pharmaceutical analysis. (Seminar)
34      Application of electroanalytical methods in pharmaceutical analysis. (Seminar)
35      Application of electroanalytical methods in pharmaceutical analysis. (Seminar)
36      Application of electroanalytical methods in pharmaceutical analysis. (Seminar)
37      Potentiometry I. Principles of potentiometry. Direct potentiometry and potentiometric titration. Determination of a strong and a
        weak acid in mixtures.
38      Potentiometry I. Principles of potentiometry. Direct potentiometry and potentiometric titration. Determination of a strong and a
        weak acid in mixtures.
39      Potentiometry I. Principles of potentiometry. Direct potentiometry and potentiometric titration. Determination of a strong and a
        weak acid in mixtures.
40      Potentiometry I. Principles of potentiometry. Direct potentiometry and potentiometric titration. Determination of a strong and a
        weak acid in mixtures.
41      Potentiometry II. Electrodes used in potentiometry. Definition and importance of the pKa value. Determination of the pKa by
        direct potentiometric titration.
42      Potentiometry II. Electrodes used in potentiometry. Definition and importance of the pKa value. Determination of the pKa by
        direct potentiometric titration.
43      Potentiometry II. Electrodes used in potentiometry. Definition and importance of the pKa value. Determination of the pKa by
        direct potentiometric titration.
44      Potentiometry II. Electrodes used in potentiometry. Definition and importance of the pKa value. Determination of the pKa by
        direct potentiometric titration.
45      Spectrophotometry III. Determination of the pKa of a weak acid and a weak base by spectrophotometry.
46      Spectrophotometry III. Determination of the pKa of a weak acid and a weak base by spectrophotometry.
47      Spectrophotometry III. Determination of the pKa of a weak acid and a weak base by spectrophotometry.

                                                                       24
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