STUDY PROGRAM 2021/2022 Subjects of the 7-8. semesters (obligatory subjects and criterion requirements)
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UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 University of Pécs Faculty of Pharmacy PHARMACY Major STUDY PROGRAM 2021/2022 Subjects of the 7-8. semesters (obligatory subjects and criterion requirements) 1
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 Table of Contents 7th semester OPG-C3E-T Pharmaceutical Technology 3 - Theory ____________________________________________________________ 3 OPG-C3G-T Pharmaceutical Technology 3 - Practice____________________________________________________________ 5 OPG-D1E-T Pharmacodynamics 1 - Theory ___________________________________________________________________ 8 OPG-D1G-T Pharmacodynamics 1 - Practice _________________________________________________________________ 11 OPG-GAI-T Pharmaceutical Applied Immunology ____________________________________________________________ 13 OPG-GI2-T Pharmaceutical Practice and Management 1 _______________________________________________________ 15 OPG-PPA-T Pharmaceutical Pathology _____________________________________________________________________ 18 OPG-R3E-T Pharmaceutical Chemistry 3 - Theory ____________________________________________________________ 20 OPG-R3G-T Pharmaceutical Chemistry 3 - Practice ____________________________________________________________ 23 OPO-KE1-T Public Health 1 ______________________________________________________________________________ 26 8th semester OPG-C4E-T Pharmaceutical Technology 4 - Theory ___________________________________________________________ 28 OPG-C4G-T Pharmaceutical Technology 4 - Practice___________________________________________________________ 30 OPG-D2E-T Pharmacodynamics 2 - Theory __________________________________________________________________ 32 OPG-D2G-T Pharmacodynamics 2 - Practice _________________________________________________________________ 35 OPG-GBI-T Pharmaceutical Biotechnology __________________________________________________________________ 37 OPG-KL1-T Clinical Studies 1 ____________________________________________________________________________ 39 OPG-R4E-T Pharmaceutical Chemistry 4 - Theory ____________________________________________________________ 41 OPG-R4G-T Pharmaceutical Chemistry 4 - Practice ____________________________________________________________ 43 OPG-TXA-T Toxicology _________________________________________________________________________________ 46 OPG-U3E-T Pharmaceutical Practice and Management 2 - Theory ________________________________________________ 49 OPG-U3G-T Pharmaceutical Practice and Management 2 - Practice _______________________________________________ 53 OPO-KE2-T Public Health 2 ______________________________________________________________________________ 55 2
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 OPG-C3E-T PHARMACEUTICAL TECHNOLOGY 3 - THEORY Course director: DR. SZILÁRD PÁL, assistant professor Institute of Pharmaceutical Technology and Biopharmacy szilard.pal@aok.pte.hu 2 credit ▪ semester exam ▪ Pharm. theoretical module and practical skills subject ▪ autumn semester ▪ recommended semester: 7 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 1 – 80 Prerequisites: see your Recommended Curriculum Topic Mainly semisolid dosage forms are prepared in this semester: suppositories and vaginal suppositories. Powders and capsules as solid dosage forms are also prepared and discussed. Conditions for acceptance of the semester Code of Studies and Regulations Mid-term exams Students have to write three assessments during the semester and they have to reach 60 % after average calculation. After two assessments if students reach average 60 % taking into account both tests, writing the third assesment it not compulsory. The third assessments (which is considered as the 1st retake) has to above 60,1 %. If the student fails on the 3rd assessment, there is still chance for the 2nd retake, where student has to reach 60,1% for the acceptance of the semester. In case of confirmed absence from the assessment, re-take chance is sossible for the student. Missing the re-take results 0 % assessment. Making up for missed classes Students must fulfil requirements determined by the Code of Studies and Examinations. Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature European Pharmacopoeia Formulae Normales VII. (FoNo VII.) James Swarbrick: Encyclopedia of Pharmaceutical Technology, Informa Healthcare, New York, London Gilbert S. Banker, Christopher T. Rhodes: Modern Pharmaceutics, Marcel Dekker Inc., New York- Basel Chris Langley, Dawn Belcher: Pharmaceutical Compounding and Dispensing, Pharmaceutical Press www.gytk.pte.hu www.sciencedirect.com Attila Dévay: The Theory and Practice of Pharmaceutical Technology, electronic book, PTE-Pécs Attila Dévay: Investigation of Pharmaceutical Preparations, electronic book, PTE-Pécs Lectures 1 Crystallisation, polymorphism, and their technological aspects Dr. Secenji Aleksandar 2 Crystallisation, polymorphism, and their technological aspects Dr. Secenji Aleksandar 3 Drying, freeze-drying Dr. Secenji Aleksandar 4 Drying, freeze-drying Dr. Secenji Aleksandar 5 Grinding and shieving Dr. Pál Szilárd 6 Grinding and shieving Dr. Pál Szilárd 7 Preparation of granules I Dr. Pál Szilárd 8 Preparation of granules I Dr. Pál Szilárd 9 Preparation of granules II Dr. Pál Szilárd 3
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 10 Written test Dr. Pál Szilárd 11 Fluidization and its application Dr. Kása Péter 12 Fluidization and its application Dr. Kása Péter 13 Pharmaceutical excipients of granules Dr. Pál Szilárd 14 Pharmaceutical excipients of granules Dr. Pál Szilárd 15 Tabletting I Dr. Pál Szilárd 16 Tabletting I Dr. Pál Szilárd 17 Tabletting II (excipients, examinations) Dr. Pál Szilárd 18 Tabletting II (excipients, examinations) Dr. Pál Szilárd 19 Excipients for the preparation of tablets and granules Dr. Pál Szilárd 20 Written test Dr. Pál Szilárd 21 Coating of preparations Dr. Kása Péter 22 Coating of preparations Dr. Kása Péter 23 Pharmaceutical capsules Dr. Pál Szilárd 24 Pharmaceutical capsules Dr. Pál Szilárd 25 Written test Dr. Pál Szilárd 26 Written test Dr. Pál Szilárd 27 Inhaled drug delivery systems Dr. Kása Péter 28 Inhaled drug delivery systems Dr. Kása Péter Practices Seminars Exam topics/questions The end-semester exam will be evaluated by a five-grade system. Knowledge acquired is tested based on subject matter defined by a list of topics provided by the institute. At the end of semester, students take written exam. The date of "A" chance exam is in determined date for students finishing the course. Chance "B" and "C"are oral exams, which is preceded by the "Minimum Test" (MT). To write the MT, students have at most 30 minutes, and will be evaluated percent rating. Those students, who achieve less than 60% in MT, unsatisfactory grade will be assessed and cannot pass them to the oral part of the exam. Oral part includes two topics. In the case of any part done with insufficient knowledge, will result in assessment of the exam to unsatisfactory grade. In addition to the exam topics, part of the exam is answering questions that aim at assessing the general knowledge of the student. Participants 4
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 OPG-C3G-T PHARMACEUTICAL TECHNOLOGY 3 - PRACTICE Course director: DR. SZILÁRD PÁL, assistant professor Institute of Pharmaceutical Technology and Biopharmacy szilard.pal@aok.pte.hu 5 credit ▪ midsemester grade ▪ Pharm. theoretical module and practical skills subject ▪ autumn semester ▪ recommended semester: 7 Number of hours/semester: 0 lectures + 70 practices + 0 seminars = total of 70 hours Course headcount limitations (min.-max.): 1 – 80 Prerequisites: see your Recommended Curriculum Topic Mainly semisolid dosage forms are prepared in this semester: suppositories and vaginal suppositories. Powders and capsules as solid dosage forms are also prepared and discussed. Conditions for acceptance of the semester 1. Accepted preparations made on practices. 2. Accepted work reports. 3. Accepted practical and theoretical assessments. 4. At the beginning of all practice classes students write short tests of different types (dose checking, synonim names and latin expressions, calculations). Semester only can be accepted if students reach at least 50% from each short test type. Mid-term exams Students have to participate two practice tests. Making up for missed classes Students must fulfil requirements determined by the Code of Studies and Examinations. All missed or failed preparations manufactured on the practice should be made up on supplementary practices! Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature European Pharmacopoeia Formulae Normales VII. (FoNo VII.) James Swarbrick: Encyclopedia of Pharmaceutical Technology, Informa Healthcare, New York, London Gilbert S. Banker, Christopher T. Rhodes: Modern Pharmaceutics, Marcel Dekker Inc., New York- Basel Chris Langley, Dawn Belcher: Pharmaceutical Compounding and Dispensing, Pharmaceutical Press www.gytk.pte.hu www.sciencedirect.com Attila Dévay: The Theory and Practice of Pharmaceutical Technology, electronic book, PTE-Pécs Attila Dévay: Investigation of Pharmaceutical Preparations, electronic book, PTE-Pécs Lectures Practices 1 Sugar and film coating process 1 Sugar and film coating process 1 Sugar and film coating process 1 Sugar and film coating process 1 Sugar and film coating process 2 End semester assessment 2 End semester assessment 2 End semester assessment 2 End semester assessment 2 End semester assessment 3 General instructions, rules and regulations on practices, introduction to solid forms 3 General instructions, rules and regulations on practices, introduction to solid forms 3 General instructions, rules and regulations on practices, introduction to solid forms 3 General instructions, rules and regulations on practices, introduction to solid forms 5
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 3 General instructions, rules and regulations on practices, introduction to solid forms 4 Undivided (bulk) powders, dusting powders, species I 4 Undivided (bulk) powders, dusting powders, species I 4 Undivided (bulk) powders, dusting powders, species I 4 Undivided (bulk) powders, dusting powders, species I 4 Undivided (bulk) powders, dusting powders, species I 5 Undivided (bulk) powders, dusting powders, species II 5 Undivided (bulk) powders, dusting powders, species II 5 Undivided (bulk) powders, dusting powders, species II 5 Undivided (bulk) powders, dusting powders, species II 5 Undivided (bulk) powders, dusting powders, species II 6 Divided powders I 6 Divided powders I 6 Divided powders I 6 Divided powders I 6 Divided powders I 7 Divided powders II 7 Divided powders II 7 Divided powders II 7 Divided powders II 7 Divided powders II 8 Dusting powders 8 Dusting powders 8 Dusting powders 8 Dusting powders 8 Dusting powders 9 Pills, hard gelatin capsules 9 Pills, hard gelatin capsules 9 Pills, hard gelatin capsules 9 Pills, hard gelatin capsules 9 Pills, hard gelatin capsules 10 Assessment 10 Assessment 10 Assessment 10 Assessment 10 Assessment 11 Preparation of garnules I, drying 11 Preparation of garnules I, drying 11 Preparation of garnules I, drying 11 Preparation of garnules I, drying 11 Preparation of garnules I, drying 12 Preparation of garnules II, examinations 12 Preparation of garnules II, examinations 12 Preparation of garnules II, examinations 12 Preparation of garnules II, examinations 12 Preparation of garnules II, examinations 13 Tabletting I., Machines 13 Tabletting I., Machines 13 Tabletting I., Machines 13 Tabletting I., Machines 13 Tabletting I., Machines 14 Tabletting II., Direct compression 14 Tabletting II., Direct compression 14 Tabletting II., Direct compression 14 Tabletting II., Direct compression 14 Tabletting II., Direct compression 6
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 Seminars Exam topics/questions Website of the Institute. Participants Dr. Ferenczi Krisztina (I8U2DJ), Dr. Kása Péter (ISWPRM), Dr. Pál Szilárd (FYF5E9), Kopcsányi Márton (D3S7AX) 7
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 OPG-D1E-T PHARMACODYNAMICS 1 - THEORY Course director: DR. GÁBOR ISTVÁN PETHŐ, professor Department of Pharmacology gabor.petho@aok.pte.hu 2 credit ▪ semester exam ▪ Pharm. theoretical module and practical skills subject ▪ autumn semester ▪ recommended semester: 7 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 1 – 100 Prerequisites: see your Recommended Curriculum Topic The aim of the course is to provide the students with the pharmacological knowledge required for their future work in the field of pharmacy. Important topics are the general principles of pharmacodynamics and pharmacokinetics, pharmacology of the autonomic nervous system and the cardiovascular system. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams There is no midterm exam/test. Making up for missed classes There is no way to make up for missed classes. Reading material - Obligatory literature - Literature developed by the Department Electronic handouts are provided for most topics. - Notes - Recommended literature Rang, Dale, Ritter, Moore: Pharmacology, 9th edition, Elsevier Churchill Livingstone, 2019 B. G. Katzung (ed.): Basic and Clinical Pharmacology, 14th edition, Lange Medical Books/McGraw-Hill, 2018 Lectures 1 Introduction to neuropharmacology. General characterization of the autonomic nervous system Dr. Barthó Loránd 2 Cholinergic agonists Dr. Barthó Loránd 3 Cholinesterase inhibitors I Dr. Barthó Loránd 4 Cholinesterase inhibitors II Dr. Barthó Loránd 5 Muscarinic receptor antagonists I Dr. Barthó Loránd 6 Muscarinic receptor antagonists II Dr. Barthó Loránd 7 Neuromuscular blocking agents I Dr. Pethő Gábor István 8 Neuromuscular blocking agents II Dr. Pethő Gábor István 9 Agents acting on biosynthesis, storage, release and elimination of catecholamines I Dr. Pethő Gábor István 10 Agents acting on biosynthesis, storage, release and elimination of catecholamines II Dr. Pethő Gábor István 11 Adrenergic receptor agonists I Dr. Pethő Gábor István 12 Adrenergic receptor agonists II Dr. Pethő Gábor István 13 Adrenergic receptor antagonists I Dr. Pethő Gábor István 8
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 14 Adrenergic receptor antagonists II Dr. Pethő Gábor István 15 Pharmacology of the calcium channels I Dr. Pethő Gábor István 16 Pharmacology of the calcium channels II Dr. Pethő Gábor István 17 Drugs acting on the renin-angiotensin-aldosterone system I Dr. Poór Miklós 18 Drugs acting on the renin-angiotensin-aldosterone system II Dr. Poór Miklós 19 Diuretic drugs I Dr. Pethő Gábor István 20 Diuretic drugs II Dr. Pethő Gábor István 21 Drugs used for treating congestive heart failure I Dr. Börzsei Rita Judit 22 Drugs used for treating congestive heart failure II Dr. Börzsei Rita Judit 23 Antiarrhythmic drugs I Dr. Pethő Gábor István 24 Antiarrhythmic drugs II Dr. Pethő Gábor István 25 Antianginal drugs I Dr. Pethő Gábor István 26 Antianginal drugs II. Drugs increasing regional blood flow Dr. Pethő Gábor István 27 Antihypertensive drugs I Dr. Pethő Gábor István 28 Antihypertensive drugs II Dr. Pethő Gábor István Practices Seminars Exam topics/questions Reqirements: the exams are oral, the required topics are dealt with during the semester lectures and practical classes. The criterion of admission to the exam is the successful completion of the Pharmacodynamics 1 practice course carried out in paralell (at least satisfactory midsemester grade). Exam questions: 1. Basic mechanisms of drug actions 2. Characterization of agonist-receptor interaction: occupancy, affinity, dose-response curve, potency, efficacy 3. Significance of signal transduction mechanisms in the effects of drugs. Tachyphylaxis and tolerance to drugs 4. Mechanisms of drug antagonisms 5. Transport of drugs across membranes 6. Absorption of drugs, oral bioavailability and presystemic elimination 7. Distribution of drugs 8. Biotransformation of drugs 9. Excretion of drugs 10. Pharmacokinetics: zero and first order elimination, volume of distribution, clearance, elimination half-life, oral bioavailability, calculation of loading and maintenance doses 11. Cholinergic agonists and cholinesterase inhibitors 12. Muscarinic receptor antagonists 13. Neuromuscular blocking agents. Drugs acting on autonomic ganglia 14. Agents acting on the biosynthesis, storage, release and elimination of catecholamines 15. Adrenergic receptor agonists 16. Adrenergic receptor antagonists 17. Local anaesthetics 18. Calcium channel blockers 19. Drugs acting on the renin-angiotensin-aldosterone system 9
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 20. Diuretic drugs 21. Positive inotropic and other drugs used to treat congestive heart failure 22. Antianginal drugs. Drugs that increase regional blood flow 23. Antihypertensive drugs 24. Antiarrhythmic drug In addition to the exam topics, an important part of the exam is answering questions that aim at assessing the general knowledge of the student. Participants 10
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 OPG-D1G-T PHARMACODYNAMICS 1 - PRACTICE Course director: DR. GÁBOR ISTVÁN PETHŐ, professor Department of Pharmacology gabor.petho@aok.pte.hu 2 credit ▪ midsemester grade ▪ Pharm. theoretical module and practical skills subject ▪ autumn semester ▪ recommended semester: 7 Number of hours/semester: 0 lectures + 28 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 1 – 100 Prerequisites: see your Recommended Curriculum Topic The aim of the course is to provide the students with the pharmacological knowledge required for their future work in the field of pharmacy. Important topics are the general principles of pharmacodynamics and pharmacokinetics. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams The students receive a practice grade based on their performance during the semester. The grade will be registered in the Neptun as a midsemester grade. The grade must be at least satisfactory as a prerequisite for taking the semester exam. Around the 11th week of the semester, a written test is the base of the practice grade. The test covers the subjects of practice classes of the first 10 weeks of the semester and 50% of the available points must be reached for acceptance of the semester. Should someone fail or want to improve, they can do it one time before the end of the semester. On a final failure (that is, after the improvement attempt still below 50%), the student cannot have semester accepted. Making up for missed classes There is no way to make up for missed classes. Reading material - Obligatory literature - Literature developed by the Department Electronic handouts are provided for most topics. - Notes - Recommended literature Rang, Dale, Ritter, Moore: Pharmacology, 9th edition, Elsevier Churchill Livingstone, 2019 B. G. Katzung (ed.): Basic and Clinical Pharmacology, 14th edition, Lange Medical Books/McGraw-Hill, 2018 Lectures Practices 1 Introduction to pharmacodynamics I. Dr. Pethő Gábor István 2 Introduction to pharmacodynamics II. Dr. Pethő Gábor István 3 Basic mechanisms of drug actions Dr. Faisal Anna Zelma 4 Characterization of the agonist-receptor interaction I. Dr. Faisal Anna Zelma 5 Characterization of the agonist-receptor interaction II. Hartnerné Dr. Pohóczky Krisztina 6 Characterization of the agonist-receptor interaction III. Hartnerné Dr. Pohóczky Krisztina 7 Signal transduction mechanisms of drug receptors Dr. Mohos Violetta Karolin 8 Tachyphylaxis and tolerance Dr. Mohos Violetta Karolin 9 Mechanisms of drug antagonisms I. Hartnerné Dr. Pohóczky Krisztina 10 Mechanisms of drug antagonisms II. Hartnerné Dr. Pohóczky Krisztina 11 Transport of drugs across membranes Dr. Fliszár-Nyúl Eszter 11
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 12 Absorption of drugs I. Dr. Fliszár-Nyúl Eszter 13 Absorption of drugs II. Binding of drugs to plasma proteins Dr. Poór Miklós 14 Distribution of drugs Dr. Poór Miklós 15 Biotransformation of drugs I. Dr. Poór Miklós 16 Biotransformation of drugs II. Dr. Poór Miklós 17 Biotransformation of drugs III. Dr. Poór Miklós 18 Excretion of drugs Dr. Poór Miklós 19 Pharmacokinetic parameters I. Dr. Fliszár-Nyúl Eszter 20 Pharmacokinetic parameters II. Dr. Fliszár-Nyúl Eszter 21 Local anesthetics I. Dr. Pethő Gábor István 22 Local anesthetics II. Dr. Pethő Gábor István 23 Drugs acting on autonomic ganglia Dr. Pethő Gábor István 24 Theoretical basis of the modulation of the pharmacology of the automatic nervous system Dr. Pethő Gábor István 25 Discussion of the pharmacology of the parasympathetic nervous system I. Dr. Barthó Loránd 26 Discussion of the pharmacology of the parasympathetic nervous system II. Dr. Barthó Loránd 27 Discussion of the pharmacology of the sympathetic nervous system I. Dr. Barthó Loránd 28 Discussion of the pharmacology of the sympathetic nervous system II. Dr. Barthó Loránd Seminars Exam topics/questions 1. Basic mechanisms of drug actions 2. Characterization of agonist-receptor interaction: occupancy, affinity, dose-response curve, potency, efficacy 3. Significance of signal transduction mechanisms in the effects of drugs. Tachyphylaxis and tolerance to drugs 4. Mechanisms of drug antagonisms 5. Transport of drugs across membranes 6. Absorption of drugs, oral bioavailability and presystemic elimination 7. Distribution of drugs 8. Biotransformation of drugs 9. Excretion of drugs 10. Pharmacokinetics: zero and first order elimination, volume of distribution, clearance, elimination half-life, oral bioavailability, calculation of loading and maintenance doses Participants Dr. Barthó Loránd (DK1RNK), Dr. Faisal Anna Zelma (KVG5NA), Dr. Fliszár-Nyúl Eszter (TUOYWS), Dr. Mohos Violetta Karolin (K9WTSC), Dr. Pethő Gábor István (F2YVEE), Dr. Poór Miklós (ARWF5Z), Hartnerné Dr. Pohóczky Krisztina (OX02SO) 12
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 OPG-GAI-T PHARMACEUTICAL APPLIED IMMUNOLOGY Course director: DR. JUDIT ERZSÉBET PONGRÁCZ, professor Department of Pharmaceutical Biotechnology pongracz.e.judit@pte.hu 2 credit ▪ semester exam ▪ Pharm. theoretical module and practical skills subject ▪ autumn semester ▪ recommended semester: 7 Number of hours/semester: 14 lectures + 0 practices + 14 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 50 Prerequisites: see your Recommended Curriculum Topic Immunology from a pharmaceutical aspect. The course material is designed to provide theoretical background to the effects of currently employed drugs on the immune system. The course will discuss the latest advances in understanding of immune cells after treatment with various medicines including antimicrobials, cancer drugs, etc. and how these drugs modify the immune response to aid or inhibit recovery from a particular disease. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Written test Making up for missed classes According to the Code of Studies and Examinations. Reading material - Obligatory literature - Literature developed by the Department Lecture and seminar ppt - Notes Lecture notes, learning materials of the lectures are available on MeetStreet Pharmaceutical Applied Immunology 2019 - Recommended literature Lectures 1 Immunology: a pharmaceutical perspective – Immune effects of drugs acting on the nervous system Dr. Pongrácz Judit Erzsébet 2 Bacterial infection – Effects of antibiotics on the immune system Dr. Pongrácz Judit Erzsébet 3 Viral infection I. – Effects of antiviral drugs on the immune system Dr. Pongrácz Judit Erzsébet 4 Viral infection II. – Effects of antiviral drugs on the immune system Dr. Pongrácz Judit Erzsébet 5 Parasite infection – Effects of anti-parasitic drugs on the immune system Dr. Pongrácz Judit Erzsébet 6 Fungal infection – Effects of antifungal drugs on the immune system Dr. Pongrácz Judit Erzsébet 7 Vitamins and the immune system – Effects of vitamins on the immune system Dr. Pongrácz Judit Erzsébet 8 Tumors and immunotherapy – Effects of chemotherapy on the immune system Dr. Pongrácz Judit Erzsébet 9 Tumors and immunotherapy – Immunological agents used in cancer therapy and their effects on the immune system Dr. Pongrácz Judit Erzsébet 10 Hypersensitive reactions I. – Immune effects of drugs used in the therapy of hypersensitivity reactions Dr. Pongrácz Judit Erzsébet 11 Hypersensitive reactions II. – Immune effects of drugs used in the therapy of hypersensitivity reactions Dr. Pongrácz Judit Erzsébet 12 Vaccination – Effects of vaccines on the immune system Dr. Pongrácz Judit Erzsébet 13 Novel therapies using the immune system Dr. Pongrácz Judit Erzsébet 13
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 14 Personalized therapies Dr. Pongrácz Judit Erzsébet Practices Seminars 1 Immune effects of drugs acting on the nervous system Elhusseiny Mohamed Mahmoud 2 Effects of antibiotics on the immune system Elhusseiny Mohamed Mahmoud 3 Effects of antiviral drugs on the immune system I Elhusseiny Mohamed Mahmoud 4 Effects of antiviral drugs on the immune system II Elhusseiny Mohamed Mahmoud 5 Effects of anti-parasitic drugs on the immune system Elhusseiny Mohamed Mahmoud 6 Fungal infection – Effects of antifungal drugs on the immune system Elhusseiny Mohamed Mahmoud 7 Effects of vitamins on the immune system Elhusseiny Mohamed Mahmoud 8 Effects of chemotherapy on the immune system Elhusseiny Mohamed Mahmoud 9 Immunological agents used in cancer therapy and their effects on the immune system Elhusseiny Mohamed Mahmoud 10 Immune effects of drugs used in the therapy of hypersensitivity reactions I Elhusseiny Mohamed Mahmoud 11 Immune effects of drugs used in the therapy of hypersensitivity reactions II Elhusseiny Mohamed Mahmoud 12 Effects of vaccines on the immune system Elhusseiny Mohamed Mahmoud 13 Novel therapies using the immune system Elhusseiny Mohamed Mahmoud 14 Personalized therapies Elhusseiny Mohamed Mahmoud Exam topics/questions MeetStreet Participants Abdelwahab Elhusseiny Mohamed Mahmoud (ZYY8OB) 14
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 OPG-GI2-T PHARMACEUTICAL PRACTICE AND MANAGEMENT 1 Course director: DR. LAJOS BOTZ, professor Department of Pharmaceutics and University Pharmacy botz.lajos@pte.hu 3 credit ▪ semester exam ▪ Pharm. theoretical module and practical skills subject ▪ autumn semester ▪ recommended semester: 7 Number of hours/semester: 28 lectures + 0 practices + 14 seminars = total of 42 hours Course headcount limitations (min.-max.): 5 – 50 Prerequisites: see your Recommended Curriculum Topic The topics of the semester introduce the basic functioning of the pharmaceutical and health-care market, further the basic fundamentals of economics relevant for pharmacy students. Methods of comprehensive analysis, evaluation and development of drug therapy, healthcare systems, the framework and regulation of pharmaceutical supply will be covered throughout the semester. Interactive discussions will cover essential topics regarding self-medication and over the counter products used in minor diseases. Students will improve their communicational skills in order to counsel patients more efficiently and improve adherence to medications. The undergraduates will acquire knowledge of the innovation of a new drug from a drug candidate, the formation of indications, marketing authorization, the life cycle of medicines and generics, as well as professional aspects of medication errors and adverse event. Students can access the slides of the lectures and further reading material on a designated web based interface (e.g. MS Teams and/or Neptun Meet Street). Conditions for acceptance of the semester - Regular attendance of classes (maximum 25 % of absence is accepted), - Assignments given in class should be carried out during term-time and, - Written mid-term and end-of-the term test. Passing the tests is not obligatory; however advisable as you will likely have better results and a good recommended grade for PPM1.There is a retake opportunity only for the end-of-the term test. Mid-term exams End-of-the-term test is at the regular time of lectures. The test will be on the whole semester’s curriculum. Additional questions can be included in the end-of-the-term test, if the student has not carried out an assignment during the semester or in case of unsuccessful midterm test. In case of unsuccessful or missed end-of-the term test, a retake opportunity is granted to make up during the last week of the semester. The end-of-the term test grade may be accepted as an examination grade, if passed. Making up for missed classes Retake opportunity is possible following personal discussion for the end-of-the term test. Reading material - Obligatory literature - Literature developed by the Department List of study aids to acquire curriculum (books, notes, other) and all presentations can be downloaded from MS Teams and/or Neptun MeetStreet. - Notes - Recommended literature J.L. Bootman, R. J. Townsend, W. F. McGhan (eds.): Principles of Pharmacoeconomics, Harvey Whitney Book Company, 2002. Robert S. Beardsley, Carole L. Kimberlin, William N. Tindall: Communication Skills in Pharmacy Practice, 6th edition, Wolters Kluwer, Lipincott Williams & Wilkins, 2012. Rosemary R. Berardi, Stefanie P. Ferreri et al.: Handbook of Nonpresciption Drugs, 17th edition, American Pharmacists Association, 2012. John P. Griffin, John Posner, Geoffrey R. Barker: The Textbook of Pharmaceutical Medicine, 7th Edition, 2013. Paul Rutter: Community Pharmacy - Symptoms, Diagnosis and Treatment. 4th Edition Elsevier 2017. Lectures 1 Drug authorization process, Patent of drugs 1 Dr. Miseta Ildikó 2 Drug authorization process, Patent of drugs 2 Dr. Miseta Ildikó 3 Variations of authorization processes (orphan drugs, generic, etc.) Dr. Miseta Ildikó 4 Drug Research and Development Dr. Vida Róbert György 15
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 5 Nonclinical studies, preclinical development, Design and methodology in clinical trials Dr. Vida Róbert György 6 Clinical trials 1 Dr. Vida Róbert György 7 Clinical trials 2 Dr. Vida Róbert György 8 The drug supply chain, participants of the drug market 1. Dr. Fittler András Tamás 9 The drug supply chain, participants of the drug market 2. Dr. Fittler András Tamás 10 Prescribing and reimbursement of medicines in Hungary 1. Dr. Fittler András Tamás 11 Prescribing and reimbursement of medicines in Hungary 2. Dr. Fittler András Tamás 12 Equivalencies of drugs 1 Dr. Miseta Ildikó 13 Equivalencies of drugs 2 Dr. Miseta Ildikó 14 Midterm test Dr. Vida Róbert György 15 Pharmacovigilance 1 Dr. Fittler András Tamás 16 Pharmacovigilance 2 Dr. Fittler András Tamás 17 Organisation of Hungarian health system Dr. Vida Róbert György 18 Principles and basic terms of economics Dr. Fittler András Tamás 19 Requirements of opening and operation of pharmacies. Regulation of public drug supply. Dr. Vida Róbert György 20 Market mechanisms. Economic actors, sectors of economy. Dr. Fittler András Tamás 21 Perfect market and health market 1. Dr. Fittler András Tamás 22 Perfect market and health market 2. Dr. Fittler András Tamás 23 Social insurance, healthcare systems. Dr. Bella Richárd 24 Regulation regarding prescribing and dispensing of medicines in Hungary. Limitation of distribution of medicines in the EU. Dr. Fittler András Tamás 25 Requirements of opening and operation of pharmacies. Regulation of public drug supply Dr. Fittler András Tamás 26 End-of-the term test Dr. Fittler András Tamás 27 End-of-the term test Dr. Vida Róbert György 28 End-of-the term test Dr. Fittler András Tamás Practices Seminars 1 Basics of communication. Importance of good communication in pharmacy. Dr. Fittler András Tamás 2 Steps of good communication 1. Dr. Miseta Ildikó 3 Steps of good communication 2. Dr. Miseta Ildikó 4 Written communication, oral presentation. Dr. Fittler András Tamás 16
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 5 Introduction - self-care, legal issues. Dr. Fittler András Tamás 6 Introduction - patient assessment and consultation. Dr. Fittler András Tamás 7 Midterm test Dr. Fittler András Tamás 8 Sample presentation, PowerPoint presentation scheme. Dr. Fittler András Tamás 9 Nutrition, mineral replacement and vitamins. Dr. Bella Richárd 10 Dry skin, atopic dermatitis, acne. Dr. Somogyi-Végh Anna 11 Smoking cessation. Dr. Somogyi-Végh Anna 12 Minor burns, wounds. Dr. Bella Richárd 13 Simulation of a small, pilot clinical study. Dr. Fittler András Tamás 14 End-of-the term test Dr. Bella Richárd Exam topics/questions Assessment of the student performance is carried out according to a five-grade scale:100-86,1% -excellent (5); 86-77,1% -good (4); 77- 68,1% -satisfactory (3); 68-60,1% -pass (2); and below 60,0% -fail (1) respectively. Final recommended grade for PPM1 is based upon the completion of the given assignments, self-care and nonprescription pharmacotherapy module, the mid-term test and the end-of-the term test. There is no practical grade for PPM1. Participants Dr. Bella Richárd (IL65ZJ), Dr. Fittler András Tamás (IYR5HQ), Dr. Miseta Ildikó (B743LU), Dr. Somogyi-Végh Anna (CPFSLI) 17
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 OPG-PPA-T PHARMACEUTICAL PATHOLOGY Course director: DR. LIVIA VIDA, specialist Department of Pathology vida.livia@pte.hu 1 credit ▪ semester exam ▪ Pharm. theoretical module and practical skills subject ▪ autumn semester ▪ recommended semester: 7 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 100 Prerequisites: see your Recommended Curriculum Topic Our course is devoted to interpret the patholgic basis of diseases to pharmacist undergraduates. Our aim is to present the study of the structural, biochemical, and functional changes in cells, tissues and organs that underlie diseases. By the use of molecular, microand macromorphologic techniques, pathology attempts to provide diagnosis and a rational basis for clinical care and therapy, placing special emphasis on pharmacotherapeutic aspects. Pathology serves as the bridge between the basic sciences and clinical studies and is the scientific foundation for the entirety of the medicine. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Students will have two midterm exams (around week 7 and 14). The final grade is calculated as the arithmetic average of the two midterms' results. Making up for missed classes There is no opportunity to make up missed classes. Reading material - Obligatory literature - Literature developed by the Department Lecture handouts are provided. Recorded lectures in mp4 format are also available. - Notes - Recommended literature Robbins Basic Pathology, 10th Edition. Lectures 1 Disease types in the human body. Necrosis. Acute and chronic inflammation. Oncology basic concepts. Dr. Vida Livia 2 Disease types in the human body. Thronbosis and embolisation. Pathology of the immune system. Dr. Vida Livia 3 Cardiovascular diseases I. Heart diseases. Disease of arteries and veins. Dr. Vida Livia 4 Cardiovascular diseases II. High blood pressure. Valvular diseases. Developmental malformations. Dr. Vida Livia 5 Diseases of the respiratory system I. Upper and lower airway infections. Asthma. Acute lung injury. Dr. Vida Livia 6 Diseases of the respiratory system II. COPD. Pneumoconioses. Laryngeal and lung cancer. Dr. Vida Livia 7 Diseases of the liver and the biliary system. Liver failure. Hepatitides. Cholelithiasis. Pancreatitis. Malignant diseases. Dr. Vida Livia 8 Diseases of the kidney and the male genitalia. Glomerulonephritides. Pyelonephritides. Kidney stones. Diseases of the testis and the prostate. Malignant diseases. Dr. Kaszás Bálint 9 Diseases of the gastrointestinal tract I. Diseases of the oral cavity, the esophagus and the stomach. Dr. Kaszás Bálint 10 Diseases of the gastrointestinal tract II. Diseases of the small and the large intestine. Dr. Kaszás Bálint 11 Diseases of the hemopoetic system. Anemias. Hodgkin lymphoma. Non-hodgkin lymphomas. Acute leukaemias. Dr. Kaszás Bálint 12 Diseases of the endocrine system. Pituitary, thyroid and adrenal gland diseases. Dr. Kaszás Bálint 18
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 13 Diseases of the central nervous system. Circulatory dysturbances. Dementias. Infections. Demyelinisating and malignant diseases. Dr. Kaszás Bálint 14 Diseases of the female genital tract. Breast cancer. Cervical cancer. Endometriosis. Dr. Kaszás Bálint Practices Seminars Exam topics/questions Disease types in the human body. Cardiovascular diseases. Diseases of the respiratory system. Diseases of the liver and the biliary system. Diseases of the kidney and the male genitalia. Diseases of the gastrointestinal tract. Diseases of the hemopoetic system. Diseases of the endocrine system. Diseases of the central nervous system. Diseases of the female genital tract. Participants 19
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 OPG-R3E-T PHARMACEUTICAL CHEMISTRY 3 - THEORY Course director: DR. ZSUZSANNA ROZMER, assistant professor Department of Pharmaceutical Chemistry rozmer.zsuzsanna@pte.hu 3 credit ▪ semester exam ▪ Pharm. theoretical module and practical skills subject ▪ autumn semester ▪ recommended semester: 7 Number of hours/semester: 42 lectures + 0 practices + 0 seminars = total of 42 hours Course headcount limitations (min.-max.): 5 – 50 Prerequisites: see your Recommended Curriculum Topic Introduction to molecular aspect, structure-activity relationship and pharmacopoeal qualification of selected group of active pharmaceutical ingredients. Basic principles and application of the analytical methods most frequently used in the pharmacopoeal qualifications. Conditions for acceptance of the semester Acknowledgement of the course is in accord with the Code of Studies and Examinations. Participation is both the lectures and the practices is obligatory. Maximum three absences can be accepted both from lectures and practices. Students have to write two midterm tests (week 7. and 12.) from the topics of the theory and the practice. One of the test result should be above 60%, the average of the tests should be above 50%. One re-take test is allowed at the 14th weak of the semester. Students have to write at least four mini-tests on the practices. The average of the results must be at least 50%. The practical work (results of the written tests and the experimental work) is evaluated by a practical grade. Satisfactory (2) evaluation is the minimum requirement of acknowledgement of the semester. Mid-term exams Students have to write two midterm tests (week 7. and 12.) from the topics of the theory and the practice. One of the test result should be above 60%, the average of the tests should be above 50%. One re-take test is allowed at the 14th weak of the semester. Students have to write at least four mini-tests on the practices. The average of the results must be at least 50%. The practical work (results of the written tests and the experimental work) is evaluated by a practical grade. Satisfactory (2) evaluation is the minimum requirement of acknowledgement of the semester. Making up for missed classes There is no opportunity to make up missed classes. Reading material - Obligatory literature D.A. Williams, T.L. Lemke (eds.): Foye's Principles of Medicinal Chemistry, 7th edition, Lippincott Williams & Wilkins, Philadelphia, 2013 - Literature developed by the Department Attila Almási, Zsuzsanna Rozmer, Pál Perjési: Pharmaceutical Chemistry 1. Laboratory Experiments and Commentary, electronic educational material, PTE 2014 - Notes - Recommended literature European Pharmacopoeia, EDQM Publication Lecture notes. Lectures 1 Application of CD and ORD spectroscopy in pharmaceutical analysis. Dr. Perjési Pál 2 Application of UV-Vis spectroscopy in pharmaceutical analysis Dr. Perjési Pál 3 Application of UV-Vis spectroscopy in pharmaceutical analysis. Dr. Perjési Pál 4 Application of thermoanalytic methods in pharmaceutical analysis. Dr. Kulcsár Győző Kornél 5 Application of fluorimetry in pharmaceutical analysis. Dr. Perjési Pál 6 Application of fluorimetry in pharmaceutical analysis. Dr. Perjési Pál 7 Application of atomic absorption spectrometry and flame photometry in pharmaceutical analysis. Dr. Kulcsár Győző Kornél 8 Application of IR spectroscopy in pharmaceutical analysis. Dr. Lóránd Tamás 20
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 9 Application of IR spectroscopy in pharmaceutical analysis. Dr. Lóránd Tamás 10 Biological drugs I. Dr. Rozmer Zsuzsanna 11 Application of NMR spectroscopy in pharmaceutical analysis. Dr. Perjési Pál 12 Application of NMR spectroscopy in pharmaceutical analysis. Dr. Perjési Pál 13 Biological drugs II. Dr. Rozmer Zsuzsanna 14 Application of mass spectrometry in pharmaceutical analysis. Dr. Kulcsár Győző Kornél 15 Application of mass spectrometry in pharmaceutical analysis. Dr. Kulcsár Győző Kornél 16 Antiallergic antihistamines. Drugs for rheumatic gout I. Dr. Rozmer Zsuzsanna 17 Application of electroanalytical methods in pharmaceutical analysis. Dr. Perjési Pál 18 Application of electroanalytical methods in pharmaceutical analysis. Dr. Perjési Pál 19 Antiallegic antihistamines. Drugs for rheumatic gout II. Dr. Rozmer Zsuzsanna 20 Agents of cardiac failure. Dr. Perjési Pál 21 Agents of cardiac failure. Dr. Perjési Pál 22 Antianginal drugs. Dr. Rozmer Zsuzsanna 23 Agents of antiarythmic agents. Dr. Almási Attila 24 Agents of antiarythmic agents. Dr. Almási Attila 25 Antithrombotics, Thrombolytics, Coagulants I. Dr. Rozmer Zsuzsanna 26 Antihipertensive agents. Dr. Almási Attila 27 Antihipertensive agents. Dr. Almási Attila 28 Antithrombotics, Thrombolytics, Coagulants II. Dr. Rozmer Zsuzsanna 29 Antihiperlidemic agents. Dr. Rozmer Zsuzsanna 30 Antihiperlidemic agents. Dr. Rozmer Zsuzsanna 31 Drugs affecting thyroid functions. Dr. Almási Attila 32 Diuretics. Dr. Almási Attila 33 Diuretics. Dr. Almási Attila 34 Adrenocorticoids I. Dr. Perjési Pál 35 Drugs affecting calcium homeostatis. Dr. Rozmer Zsuzsanna 36 Drugs affecting calcium homeostatis. Dr. Rozmer Zsuzsanna 37 Adrenocorticoids II. Dr. Perjési Pál 21
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 38 Insulin and oral hypoglycemic drugs. Dr. Almási Attila 39 Insulin and oral hypoglycemic drugs. Dr. Almási Attila 40 Estrogens, Androgens, Progestins I. Dr. Perjési Pál 41 Estrogens, Androgens, Progestins II. Dr. Perjési Pál 42 Estrogens, Androgens, Progestins II. Dr. Perjési Pál Practices Seminars Exam topics/questions Written exam covering the topics of the lectures and the laboratory practices. The result of the written exam must be above 60%. The final grade is based on results of the midterm tests and the written exam. Maximum contribution of the results of the midterm tests to the total score of the written exam is 25%. Participation on the first exam is compulsory. Participants 22
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 OPG-R3G-T PHARMACEUTICAL CHEMISTRY 3 - PRACTICE Course director: DR. ZSUZSANNA ROZMER, assistant professor Department of Pharmaceutical Chemistry rozmer.zsuzsanna@pte.hu 4 credit ▪ midsemester grade ▪ Pharm. theoretical module and practical skills subject ▪ autumn semester ▪ recommended semester: 7 Number of hours/semester: 0 lectures + 56 practices + 0 seminars = total of 56 hours Course headcount limitations (min.-max.): 5 – 50 Prerequisites: see your Recommended Curriculum Topic Introduction to the most important instrumental analytical methods and their applications to pharmacopoeal qualification of active pharmaceutical ingredients and excipients in pharamaceutical formulations. Conditions for acceptance of the semester Acknowledgement of the course is in accord with the Code of Studies and Examinations. Participation in the practices is obligatory. Maximum three absences can be accepted. Students have to write at least four short tests on the practices. The average of the results must be at least 50%. The practical work (results of the written tests and the experimental work) is evaluated by a practice grade. Mid-term exams Students have to write at least four short tests on the practices. The average of the results must be at least 50%. The practical work (results of the written tests and the experimental work) is evaluated by a practice grade. Making up for missed classes There is no opportunity to make up missed classes. Reading material - Obligatory literature D.A. Williams, T.L. Lemke (eds.): Foye's Principles of Medicinal Chemistry, 7th edition, Lippincott Williams & Wilkins, Philadelphia, 2013 - Literature developed by the Department Attila Almási, Zsuzsanna Rozmer, Pál Perjési: Pharmaceutical Chemistry 1. Laboratory Experiments and Commentary, electronic educational material, PTE 2014 - Notes Pharmaceutical Chemistry Practice 1, laboratory manual, University of Pécs, 2015 - Recommended literature European Pharmacopoeia, EDQM Publication Lecture notes. Lectures Practices 1 Laboratory safety and accident protection. Preliminary testing and classification of inorganic and organic compounds I. Identification of 10 inorganic and organic substances I. 2 Laboratory safety and accident protection. Preliminary testing and classification of inorganic and organic compounds I. Identification of 10 inorganic and organic substances I. 3 Laboratory safety and accident protection. Preliminary testing and classification of inorganic and organic compounds I. Identification of 10 inorganic and organic substances I. 4 Laboratory safety and accident protection. Preliminary testing and classification of inorganic and organic compounds I. Identification of 10 inorganic and organic substances I. 5 Preliminary testing and classification of inorganic and organic compounds II. Identification of 10 inorganic and organic substances II. 6 Preliminary testing and classification of inorganic and organic compounds II. Identification of 10 inorganic and organic substances II. 7 Preliminary testing and classification of inorganic and organic compounds II. Identification of 10 inorganic and organic substances II. 8 Preliminary testing and classification of inorganic and organic compounds II. Identification of 10 inorganic and organic substances II. 9 Principles of validation of analytical methods. (Seminars) 10 Principles of validation of analytical methods. (Seminars) 11 Principles of validation of analytical methods. (Seminars) 12 Principles of validation of analytical methods. (Seminars) 23
UP FP Pharmacy major – Obligatory subjects in the 7-8. rec. semester - Course descriptions – academic year of 2021/2022 13 Validation of a titrimetric methods. Comparison of different methods, Determination of sodium hydrogen carbonate according to the Ph. Hg. VII. and the Ph. Hg. VIII. 14 Validation of a titrimetric methods. Comparison of different methods, Determination of sodium hydrogen carbonate according to the Ph. Hg. VII. and the Ph. Hg. VIII. 15 Validation of a titrimetric methods. Comparison of different methods, Determination of sodium hydrogen carbonate according to the Ph. Hg. VII. and the Ph. Hg. VIII. 16 Validation of a titrimetric methods. Comparison of different methods, Determination of sodium hydrogen carbonate according to the Ph. Hg. VII. and the Ph. Hg. VIII. 17 Spectrophotometry I. The Lambert-Beer's law. Determination of specific absorbance. Spectrophotometric determination of coffein, aminophenazone and paracetamol in powder mixtures. 18 Spectrophotometry I. The Lambert-Beer's law. Determination of specific absorbance. Spectrophotometric determination of coffein, aminophenazone and paracetamol in powder mixtures. 19 Spectrophotometry I. The Lambert-Beer's law. Determination of specific absorbance. Spectrophotometric determination of coffein, aminophenazone and paracetamol in powder mixtures. 20 Spectrophotometry I. The Lambert-Beer's law. Determination of specific absorbance. Spectrophotometric determination of coffein, aminophenazone and paracetamol in powder mixtures. 21 Spectrophotometry II. Determination of salicylic acid and acetylsalicylic acid in mixtures by spectrophotometric and alkalimetric methods. 22 Spectrophotometry II. Determination of salicylic acid and acetylsalicylic acid in mixtures by spectrophotometric and alkalimetric methods. 23 Spectrophotometry II. Determination of salicylic acid and acetylsalicylic acid in mixtures by spectrophotometric and alkalimetric methods. 24 Spectrophotometry II. Determination of salicylic acid and acetylsalicylic acid in mixtures by spectrophotometric and alkalimetric methods. 25 Application of fluometric methods. Application of NMR in pharmaceutical analysis. Principles of evaluation of NMR spectra. Evaluation of 1H and 13C NMR spectra of selected drug substances. (Seminar) 26 Application of fluometric methods. Application of NMR in pharmaceutical analysis. Principles of evaluation of NMR spectra. Evaluation of 1H and 13C NMR spectra of selected drug substances. (Seminar) 27 Application of fluometric methods. Application of NMR in pharmaceutical analysis. Principles of evaluation of NMR spectra. Evaluation of 1H and 13C NMR spectra of selected drug substances. (Seminar) 28 Application of fluometric methods. Application of NMR in pharmaceutical analysis. Principles of evaluation of NMR spectra. Evaluation of 1H and 13C NMR spectra of selected drug substances. (Seminar) 29 Application of IR in pharmaceutical analysis. Principles of evaluation of IR spectra. Evaluation of IR spectra of selected drug substances. (Seminar) Application of mass spectrometry methods. 30 Application of IR in pharmaceutical analysis. Principles of evaluation of IR spectra. Evaluation of IR spectra of selected drug substances. (Seminar) Application of mass spectrometry methods. 31 Application of IR in pharmaceutical analysis. Principles of evaluation of IR spectra. Evaluation of IR spectra of selected drug substances. (Seminar) Application of mass spectrometry methods. 32 Application of IR in pharmaceutical analysis. Principles of evaluation of IR spectra. Evaluation of IR spectra of selected drug substances. (Seminar) Application of mass spectrometry methods. 33 Application of electroanalytical methods in pharmaceutical analysis. (Seminar) 34 Application of electroanalytical methods in pharmaceutical analysis. (Seminar) 35 Application of electroanalytical methods in pharmaceutical analysis. (Seminar) 36 Application of electroanalytical methods in pharmaceutical analysis. (Seminar) 37 Potentiometry I. Principles of potentiometry. Direct potentiometry and potentiometric titration. Determination of a strong and a weak acid in mixtures. 38 Potentiometry I. Principles of potentiometry. Direct potentiometry and potentiometric titration. Determination of a strong and a weak acid in mixtures. 39 Potentiometry I. Principles of potentiometry. Direct potentiometry and potentiometric titration. Determination of a strong and a weak acid in mixtures. 40 Potentiometry I. Principles of potentiometry. Direct potentiometry and potentiometric titration. Determination of a strong and a weak acid in mixtures. 41 Potentiometry II. Electrodes used in potentiometry. Definition and importance of the pKa value. Determination of the pKa by direct potentiometric titration. 42 Potentiometry II. Electrodes used in potentiometry. Definition and importance of the pKa value. Determination of the pKa by direct potentiometric titration. 43 Potentiometry II. Electrodes used in potentiometry. Definition and importance of the pKa value. Determination of the pKa by direct potentiometric titration. 44 Potentiometry II. Electrodes used in potentiometry. Definition and importance of the pKa value. Determination of the pKa by direct potentiometric titration. 45 Spectrophotometry III. Determination of the pKa of a weak acid and a weak base by spectrophotometry. 46 Spectrophotometry III. Determination of the pKa of a weak acid and a weak base by spectrophotometry. 47 Spectrophotometry III. Determination of the pKa of a weak acid and a weak base by spectrophotometry. 24
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