Postgraduate Degree in Fetal Cardiology - Course duration: From April 12, 2021 to April 12 , 2022 First week calendar: October 18-24, 2021 Second ...
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Postgraduate Degree in Fetal Cardiology Course duration: From April 12, 2021 to April 12 , 2022 First week calendar: October 18-24, 2021 Second week: March 7-13 ,2022
TABLE OF CONTENTS 5 1. GENERAL INFORMATION 7 PRESENTATION 8 OBJECTIVES 9 INFORMATION OF INTEREST 10 TEACHING STRUCTURE 13 2. ACADEMIC PROGRAM 15 MODULE 1: ADVANCED ECHOCARDIOGRAPHY 16 MODULE 2: SEPTAL DEFECTS 17 MODULE 3: LEFT CHD 18 MODULE 4: RIGHT CHD 19 MODULE 5: CONOTRUNCAL ANOMALIES 20 MODULE 6: COMPLEX CHD-OTHER CARDIAC ANOMALIES 21 MODULE 7: VASCULAR / VENOUS SYSTEM ANOMALIES 22 MODULE 8: FETAL ARRHYTHMIAS AND FETAL CARDIAC THERAPY 24 MODULE 9: FETAL HEART ADAPTATION TO EXTRA-CARDIAC CONDITIONS / NOVEL TECHNOLOGIES 25 MODULE 10: RESEARCH PROJECT 27 3. COMPLEMENTARY TOOLS 29 MASTERCLASSES 29 RESOLUTION OF CLINICAL CASES 29 FORUM 30 RULES FOR THE USE OF THE FORUM 33 4. PRACTICUM 37 IMAGE LIST AND ASSESSMENT CRITERIA 57 5. FACE TO FACE PERIOD IN BARCELONA 61 6. RESEARCH PROJECT (MODULE 10) 69 7. EVALUATION CRITERIA
7 1 GENERAL INFORMATION PRESENTATION The aim of this course is to improve your skills and achieve excellence in the fetal diagnosis and management of congenital heart defects (CHD) as well as in the morphological and functional evaluation of the fetal heart in different conditions. Through a comprehensive approach spanning from pathophysiology to detailed imaging, the acquisition of knowledge is achieved through intensive exposure to a large number of real cases representing all possible conditions and situations found in a fetal cardio- logy unit. With a strong focus in clinical decision-making, masterclasses and a face-to-face pe- riod in Barcelona are designed to complement the specific skills in the performance of high-quality echocardiography and the evaluation of prognosis, with transversal skills in multidisciplinary interaction and parental counseling issues. The online practical part aims to complement the theoretical training by acquiring and submitting certain images in order to validate the acquisition of new competencies. Thus, the interactive program provides ample opportunities to take part in open discussions via a forum, sharing your own cases with experts in the field. Two onsite weeks at the facilities of BCNatal (Hospital Clínic and SJDBarcelona Children’s Hospital) will enable close interactions with the experts with “Meet-the-professor” ses- sions, workshops on new technologies and practical training. This unique academic program, endorsed by the University of Barcelona, addresses the ra- pidly growing demands for sub-specialists with an in-depth knowledge in Fetal Cardiology.
8 POSTGRADUATE DEGREE IN FETAL CARDIOLOGY OBJECTIVES Main academic goal • To enable participants to perform expert diagnosis and counseling of prenatal heart anomalies by in-depth knowledge of fetal cardiac physiology Specific objectives • To achieve optimal prenatal acquisition of images for the evaluation of fetal cardiac morphometry and function • To efficiently incorporate to fetal echocardiographic evaluation all related techniques, including 2D, M-mode, color and spectral Doppler, 4D-STIC, tissue Doppler, strain, and magnetic resonance • To enable participants to expert diagnosis and counseling of congenital prenatal heart anomalies and fetal arrhythmias • To enable participants to properly assess fetal cardiac function in a clinical context • To recognize the indications, limitations, and benefits of in utero cardiac therapy in a clinical context • To make predictions on how the fetal heart adapts to an insult, and the consequent fetal cardiac remodeling, dysfunction and failure • To emphatically cope with the emotional needs of parents facing during pregnancy the diagnose of a heart anomaly
9 INFORMATION OF INTEREST Target audience Advanced fetal cardiology training for Fetal Medicine specialists and ultrasound professi- onals with experience in fetal echocardiography who want to improve their understanding and clinical skills on Fetal Cardiology Organized by Fetal I+D Education Barcelona Directors and scientific committee Fátima Crispi/Olga Gómez/Josep M Martínez Fetal I+D Academic Direction and Supervision Francesc Figueras/Eduard Gratacós Scientific coordinator and webmaster Laura Nogué
10 POSTGRADUATE DEGREE IN FETAL CARDIOLOGY TEACHING STRUCTURE The Postgraduate Degree in Fetal Cardiology comprises 9 theoretical-practical modules including the basics on prenatal cardiac imaging, advanced knowledge on CHD and ar- rhythmias, and understanding on fetal cardiac function and therapy. The online modules include theoretical lectures based on clinical cases, an interactive fo- rum and a live masterclass with experts which guaranties close interaction with teachers with the aim of solving all the doubts that may arise during the modules. Each module will be complemented with the resolution of a practical clinical case in the forum, including diagnosis, prognosis and parental counseling. The clinical case is based on a real case that will be discussed during the Masterclass. Modules will be evaluated by an online test and a final online exam. The details of the evaluation will be indicated throughout this academic guide. The practical part of the postgraduate course is designed for the students to acquire the necessary skills to perform an advanced echocardiography, including a complete mor- phometric and functional evaluation of the fetal heart. To complete this practical part, the students will need to send more than 70 images and echocardiographic measurements from three different fetuses. These images will be evaluated and scored by the Academic Committee and the students will receive personalized feedback that will allow them to improve their skills. It will also be required to submit 5 documented cases of congenital heart defects obtained by the student at his/her workplaces. In addition, during the first on-site week at our center, the students will have the opportunity to participate in two “hands-on real patients” workshops with close supervision by the postgraduate directors enabling to learn tips and tricks for an optimal acquisition. The postgraduate training includes the completion of a research work under the guidance and supervision of a mentor that will be evaluated by the Academic Committee. The following section details the different modules of the course, as well as their specific content, the coordinators of the online theoretical-practical parts, and the scheduled dates for the on-site weeks. The calendar of the Masterclasses and the exams’ deadlines will be available on the Virtual Campus, to which you will be granted access prior to the course start date.
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13 2. ACADEMIC PROGRAM 2 ACADEMIC PROGRAM
15 2 ACADEMIC PROGRAM MODULE 1: ADVANCED ECHOCARDIOGRAPHY ONLINE CLASSES 1. Fetal echocardiography: Indications and content. Josep Maria Martínez 2. Techniques/ modes to perform a fetal echocardiography. Fátima Crispi 3. Fetal cardiac morphometry. Olga Gómez 4. Fetal cardiac rhythm/ heart rate. Olga Gómez 5. Fetal systolic function. Fátima Crispi 6. Fetal diastolic function. Fátima Crispi 7. Clinical application/integration. Fátima Crispi 8. Fetal heart anatomy: CHD classification. Olga Gómez TUTORS ONLINE THEORETICAL AND FÁTIMA CRISPI / OLGA GÓMEZ PRACTICAL PARTS: Masterclass coordinators Fátima Crispi fcrispi@medicinafetalbarcelona.org Olga Gómez ogomez@medicinafetalbarcelona.org IMAGES Cardiac morphometry: heart and 4-chamber view
16 POSTGRADUATE DEGREE IN FETAL CARDIOLOGY MODULE 2: SEPTAL DEFECTS ONLINE CLASSES 1. Atrioventricular septal defects I-Complete AV defect. Narcís Masoller 2. Atrioventricular septal defects II-Partial AV defect- other forms. Narcís Masoller 3. Interventricular septal defects: perimembranous defects. Narcís Masoller 4. Interventricular septal defects: muscular defectes. Narcís Masoller 5. Interauricular septal defects. Narcís Masoller 6. Single double entry ventricle. Narcís Masoller CLINICAL CASE NARCÍS MASOLLER / Septal defects JOSEP MARIA MARTÍNEZ TUTORS ONLINE Masterclass coordinators THEORETICAL AND PRACTICAL PARTS: Narcís Masoller nmasoller@medicinafetalbarcelona.org IMAGES Cardiac morphometry: 4-chamber view, 5-chamber view, 3-chamber view
17 MODULE 3: LEFT CHD ONLINE CLASSES 1. Hypoplastic left heart-I: Mitral atresia. Olga Gómez 2. Hypoplastic left heart II-Aortic atresia. Olga Gómez 3. Aortic stenosis. Olga Gómez 4. Aortic coarctation. Olga Gómez 5. Aortic arch interruption. Olga Gómez CLINICAL CASE Left CHD TUTORS ONLINE THEORETICAL AND PRACTICAL PARTS: OLGA GÓMEZ / JOSEP MARIA Olga Gómez MARTÍNEZ ogomez@medicinafetalbarcelona.org Masterclass coordinators IMAGES Cardiac morphometry: 3 vessel and traquea view
18 POSTGRADUATE DEGREE IN FETAL CARDIOLOGY MODULE 4: RIGHT CHD ONLINE CLASSES 1. Tricuspid atresia. Narcís Masoller 2. Ebstein Anomaly-Tricuspid displasia. Narcís Masoller 3. Pulmonary stenosis. Fátima Crispi 4. Pulmonary atresia - type I. Fátima Crispi 5. Pulmonary atresia - type II. Fátima Crispi CLINICAL CASE Right CHD TUTORS ONLINE THEORETICAL AND PRACTICAL PARTS: NARCÍS MASOLLER / FÁTIMA CRISPI Narcís Masoller Masterclass coordinators nmasoller@medicinafetalbarcelona.org Fátima Crispi fcrispi@medicinafetalbarcelona.org IMAGES Cardiac morphometry: sagital views
19 MODULE 5: CONOTRUNCAL ANOMALIES ONLINE CLASSES 1. Fallot Complex. Mar Bennasar 2. Truncus arteriosus. Mar Bennasar 3. D-Transposition of great arteries. Mar Bennasar 4. L-Transposition of great arteries. Mar Bennasar 5. Double outlet right ventricle. Mar Bennasar CLINICAL CASE Conotruncal anomalies TUTORS ONLINE THEORETICAL AND PRACTICAL PARTS: MAR BENNASAR / JOSEP MARIA Mar Bennasar MARTÍNEZ bennasar@medicinafetalbarcelona.org Masterclass coordinators IMAGES Cardiac morphometry: M-mode and Pused-Doppler.
20 POSTGRADUATE DEGREE IN FETAL CARDIOLOGY MODULE 6: COMPLEX CHD-OTHER CARDIAC ANOMALIES ONLINE CLASSES 1. Situs anomalies - Heterotaxy syndromes. Josep Maria Martínez 2. Fetal cardiac Tumors. Josep Maria Martínez 3. Cardiomyopathies / other myocardial abnormalities (Congenital aneurysm / diverticulum). Josep Maria Martínez 4. Other anomalies: ductus arteriosus restriction, pericardial effusion, ectopia cordis. Josep Maria Martínez CLINICAL CASE Complex CHD NARCÍS MASOLLER / FÁTIMA CRISPI TUTORS ONLINE Masterclass coordinators THEORETICAL AND PRACTICAL PARTS: Josep Maria Martínez jmmartinez@medicinafetalbarcelona.org IMAGES Right cardiac function
21 MODULE 7: VASCULAR / VENOUS SYSTEM ANOMALIES ONLINE CLASSES 1. Aortic arch anomalies: ARSA, RAA, DAA. Mar Bennasar 2. Systemic venous return anomalies I: PVCSI, IIVC. Mar Bennasar 3. Systemic venous return anomalies II: Umbilical vein drainage anomalies. Mar Bennasar 4. Pulmonary venous return anomalies. Mar Bennasar CLINICAL CASE Conotruncal anomalies TUTORS ONLINE THEORETICAL AND MAR BENNASAR / PRACTICAL PARTS: JOSEP MARIA MARTÍNEZ Mar Bennasar Masterclass coordinators bennasar@medicinafetalbarcelona.org IMAGES Cardiac morphometry: M-mode and Pused-Doppler.
22 POSTGRADUATE DEGREE IN FETAL CARDIOLOGY MODULE 8: FETAL ARRHYTHMIAS AND FETAL CARDIAC THERAPY BLOC 1: FETAL ARRHYTHMIAS ONLINE CLASSES 1. Fetal arrhythmias: classification. Olga Gómez 2. Fetal irregular rhythms (premature atrial/ventricular beats). Olga Gómez 3. Fetal Tachycardia I - Supraventricular tachycardia. Olga Gómez 4. Fetal Tachycardia II - Atrial Flutter. Olga Gómez 5. Fetal Bradycardia I - Autoimmune block. Olga Gómez 6. Fetal Bradycardia II - Others (Long QT syndrome). Olga Gómez CLINICAL CASE Fetal Arrhythmias OLGA GÓMEZ / JOSEP TUTORS ONLINE MARIA MARTÍNEZ THEORETICAL AND Masterclass coordinators PRACTICAL PARTS: Olga Gómez ogomez@medicinafetalbarcelona.org IMAGES Clinical case CHD 1 and 2
23 BLOC 2: FETAL CARDIAC THERAPY ONLINE CLASSES 1. Fetal Aortic valvuloplasty. Josep Maria Martínez 2. Fetal Atrial septostomy. Josep Maria Martínez 3. Fetal Pulmonary valvuloplasty. Josep Maria Martínez CLINICAL CASE Fetal cardiac therapy TUTORS ONLINE THEORETICAL AND PRACTICAL PARTS: Josep Maria Martínez JOSEP MARIA jmmartinez@medicinafetalbarcelona.org MARTÍNEZ / EDUARD GRATACÓS Masterclass coordinators IMAGES Clinical case CHD 3 and 4
24 POSTGRADUATE DEGREE IN FETAL CARDIOLOGY MODULE 9: FETAL HEART ADAPTATION TO EXTRA-CARDIAC CONDITIONS / NOVEL TECHNOLOGIES ONLINE CLASSES 1. Fetal cardiovascular remodeling and programing- concept. Eduard Gratacós 2. Fetal patterns - cardiovascular remodeling. Fàtima Crispi 3. Fetal heart - IUGR. Fàtima Crispi 4. Fetal heart - Assisted Reproductive Technologies. Fàtima Crispi 5. Fetal heart – Infections. Fàtima Crispi 6. Fetal heart - Monochorionic twins (Twin-to-twin transfusion syndrome/sIUGR). Mar Bennasar 7. Machine learning applied to fetal cardiology. Fàtima Crispi FÁTIMA CRISPI / CLINICAL CASE OLGA GÓMEZ Masterclass coordinators Fetal heart adaptation to extra-cardiac conditions TUTORS ONLINE THEORETICAL AND PRACTICAL PARTS: Fátima Crispi IMAGES fcrispi@medicinafetalbarcelona.org Clinical case CHD 5
25 MODULE 10: RESEARCH PROJECT TUTORS Josep Maria Martínez, Olga Gómez, Fàtima Crispi, Mar Bennasar i Narcís Masoller
27 3. COMPLEMENTARY TOOLS 3 COMPLEMENTARY TOOLS
29 3 COMPLEMENTARY TOOLS MASTERCLASSES At the end of each theoretical module, a Masterclass will be given by the director/co- ordinator of each module, with the aim of deepen the topics of greatest interest and reinforcing the knowledge acquired from the theoretical classes. These sessions will be in streaming and the students will be able to solve their doubts with the experts online. The students can send their questions in advance to the scientific coordinator who will coordinate the sessions. Masterclasses will be scheduled in advance and the date and time will be announced on the Virtual Campus. RESOLUTION OF CLINICAL CASES This part of the course is designed for the student to apply the theoretical knowledge acquired in the different modules. For this, in each module the student will have the opportunity to solve real clinical cases in the forum. It will include conducting a diffe- rential diagnosis, establishing a study protocol and a follow-up plan for each case, taking into consideration the prognostic evaluation. The high degree of expertise of the faculty team will guide participants through cases of different complexity. This novel and dynamic part of the course will allow acquiring the tools to carry out an exhaustive and systematic evaluation of most congenital heart defects from a practical management point of view. FORUM A virtual forum will be created for each module using Moodle platform. The forum will be supervised by the webmaster, who will ensure its correct use and functionality. The students will be given access once the module is open and it will be the tool for sharing questions and doubts regarding the studied topics.
30 POSTGRADUATE DEGREE IN FETAL CARDIOLOGY RULES FOR THE USE OF THE FORUM The forum is a communication tool within the virtual campus. The participation is subject to basic rules: • It is expected from the students to be up to date on the messages and try to answer their colleagues’ questions, even though there will be a teacher that will be present as a moderator and may intervene if no student can help with a question. • Before asking a question, we recommend making sure that the topic is appropriate to the specific discussion forum and that the same question has not been asked before; if this happens, the repeated question will be deleted by the webmaster. • We recommend that new messages should be short, concise and self- explanatory. • No administrative or technical related questions should be asked in the forums (for example: I can’t watch the videos; I can’t download the presentations...). These messages will be deleted. • We will try to answer the questions within the period of open forum. Those questions that remain pending will be discussed in the following masterclass. • The messages in a specific forum must match the subjects related to that forum. Any misplaced question will be deleted to keep the forums organized. • To answer a question or reply on a topic, the post must be open first and then the Reply link or button must be clicked on.
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33 4. PRACTICUM 4 PRACTICUM
35 4 PRACTICUM All the modules include a practical part that consists of obtaining and submitting a cer- tain number of ultrasound images that must meet the criteria explained in the theoreti- cal classes. • MODULE 1: • MODULE 6: May 16, 2021. Recovery deadline: October 17, 2021. Recovery deadline: August 8, 2021. November 28, 2021. • MODULE 2: • MODULE 7: June 13, 2021. Recovery deadline: November 28, 2021. Recovery deadline: August 8, 2021. April 4, 2022. • MODULE 3: • MODULE 8: July 11, 2021. Recovery deadline: January 30, 2022. Recovery deadline: August 8, 2021. April 4, 2022. • MODULE 4: • MODULE 9: August 8, 2021. Recovery deadline: March 6, 2022. Recovery deadline: November 28, 2021. April 4, 2022. • MODULE 5: • MODULE 10: September 12, 2021. Recovery dea- March 23, 2022. dline: November 28, 2021. The calendar will be available on the virtual campus. If there are any changes in the dea- dlines for any reason, it will be properly announced in the campus calendar. The images will be assessed and scored by the tutors of the course; the students will receive a personalized feedback that will allow them to detect possible pitfalls in order to improve their clinical skills.
36 POSTGRADUATE DEGREE IN FETAL CARDIOLOGY This part requires a lot of dedication from the student and it is incorporated to improve his/her performance in ultrasound scanning during his/her daily clinical practice. Some modules require also the submission of documented clinical cases with correspon- ding images, obtained by the student at his/her workplace. GENERAL GUIDELINES 1. Images from 3 different patients should be submitted for every required image in each module. Images from the same patient can be used in different modules. For example, images from the 4-chamber view (Module 1) and 3 vessels trachea images (Module 3) can be acquired from the same patient. It’s not necessary to obtain the whole set of images of each module from the same patient. 2. The evaluation criteria are those defined in the algorithms for interpreting the images described in the theoretical part of the course. 3. To obtain accreditation, at least 70% of the images must meet at least 70% of the defined criteria. 4. The images will be uploaded for each module in the TASKS SUBMISSION section in the virtual Campus. 5. All the images for each module must be submitted in a single PDF document, displayed in the requested order for each module. The document’s size must not exceed 25 MB. 6. In order to preserve the confidentiality of the patients, the submitted images must NOT show patient names or any identity related data.
37 IMAGE LIST AND ASSESSMENT CRITERIA CARDIAC MORPHOMETRY MODULE 1 Total: 9 images x 3 patients = 27 images HEART 1. Cardiac area and thoracic area- 2D: measured in a 4-chamber view at end-diastole. Value and z-score. Landmarks: external border of the ribs/right and left lungs. Cardiothoracic ratio. 2. Cardiac Sphericity index: measured in a 4-chamber view at end-diastole. Value and z-score. 4 CHAMBER VIEW 3. Apical view (2d): showing right/left atria and right/left ventricles at end-diastole.
38 POSTGRADUATE DEGREE IN FETAL CARDIOLOGY 4. Apical view (color Doppler): showing atrioventricular valvular flows at mid-diastole. 5. Transverse view (2D): showing interatrial/interventri- cular septum 6. Transverse view (color Doppler): with adequate color scale to demonstrate the integrity of the interventri- cular septum. 7. Basal view (2D): showing atrioventricular septum or integrity of the heart cross. 8. Basal view (color Doppler): demonstrating the absence of atrioventricular valvular insufficiency. 9. Pulmonary veins (color Doppler): at least two (1 left and 1 right)
39 MODULE 2 Total 12 images x 3 patients = 36 images 4 CHAMBER VIEW 10. Atrial dimensions, atrial sphericity index (2D): maxi- mum diameters (end-systole). Value and z-score. 11. Atrial dimensions (2D): area (at end-systole). Value and z-score. 12. Ventricular dimensions, ventricular sphericity in- dex: basal, mid-transverse and longitudinal diame- ters (at end-diastole). Value and z-score. 13. Ventricular dimensions: Areas (at end-diastole). Value and z-score.
40 POSTGRADUATE DEGREE IN FETAL CARDIOLOGY 5 CHAMBER VIEW 14. Left ventricle outflow tract (2d) Aortic valve: open valve (mid-systole). Value and z-score. 15. Left ventricle outflow tract (color Doppler): confir- ming continuity between the upper interventricular setpum and the anterior wall of the aorta. 16. Ascending aorta: five-chamber view (distal portion artery). Value and z-score. 3 CHAMBER VIEW 17. Right ventricle outflow tract (2D): pulmonary valve/ trunk. Open valve (mid-systole). Pulmonary valve: Value and z-score.
41 18. Right ventricle outflow tract (color Doppler): 3 ves- sel view showing a transverse section of the aorta and superior vena cava. 19. Pulmonary arteries (2D): at its bifurcation. Value and z-score. 20. Pulmonary arteries (color Doppler) 21. Pulmonary trunk: at the 3 vessel view. Value and z-score.
42 POSTGRADUATE DEGREE IN FETAL CARDIOLOGY MODULE 3 Total 10 images x 3 patients = 30 images 3 VESSEL AND TRACHEA VIEW 22. Apical view (2D): ductus arteriosus, Aortic Isthmus, Superior vena cava and Trachea. Ductus arteriosus: value and z-score. Aortic Isthmus: value and z-score 23. Apical view (color Doppler): showing anterograde and symmetrical flows. 24. Transverse view (2D): ductus arteriosus, Aortic Isth- mus, Superior vena cava and Trachea 25. Transverse view (color Doppler)
43 26. Basal view (2D): ductus arteriosus, Aortic Isthmus, Superior vena cava and Trachea. 27. Basal view (color Doppler): showing anterograde and symmetrical flows. 28. Thymus (2D): at the 3 vessels and trachea view. Thy- mus-thoracic ratio (value) 29. Thymus box (color Doppler): showing the inter- nal mammary arteries at the external border of the thymus. 30. Right subclavian artery (color Doopler): showing its normal course in front of the trachea. 31. Innominate vein (color Doppler): showing its normal drainage into the superior vena cava.
44 POSTGRADUATE DEGREE IN FETAL CARDIOLOGY MODULE 4 Total 11 images x 3 patients = 33 images SAGITAL 32. Ductal arch (2D): value and z-score of the pulmonary valve and ductus arteriosus 33. Ductal arch (color Doppler): demonstrating normal flow (“hockey stick” shape) 34. Aortic arch (2D): value and z-score of the ascending Aorta, transverse arch and aortic isthmus. 35. Aortic arch (color Doppler): demonstrating normal flow (“candy cane” shape) 36. Supra-aortic trunks (2D): common trunk, left carotid artery and left subclavian artery. Left carotid-to-sub- clavian distance: value
45 37. Supra-aortic trunks (color Doppler): demonstrating normal flow. 38. Systemic venous return (2D): identification of the superior and inferior vena cava showing their entry into the right atrium. Measurement of inferior vena cava. Value and z-score. 39. Systemic venous return (color Doppler): demonstra- ting normal direction of flow. 40. Ductus venosus (color Doppler): confirmation of its drainage at the level of inferior vena cava. 41. Suprahepatic veins (color Doppler): showing their confluence al the level of the inferior vena cava (at least two veins). 42. Portal system (color Doppler): showing the normal course of the portal sinus to the right.
46 POSTGRADUATE DEGREE IN FETAL CARDIOLOGY MODULE 5 Total 6 images x 3 patients = 18 images M-MODE 43. Transverse 4-chamber view: atrial and ventricular contraction. Measure Heart rate. 44. Transverse 4-chamber view: transverse ventricular dimensions. Values and z-scores. 45. Transverse 4-chamber view: free lateral walls and septum thickness. Values and z-scores.
47 PULSED-DOPPLER 46. Atrioventricular interval: inflow and outflow of the left ventricle (value): from the onset of the “A” mitral wave to the onset of the aortic wave. 47. Atrioventricular interval: pulmonary artery-vein from the onset of the “A” wave on the pulmonary vein to the onset of the pulmonary artery wave. 48. Atrioventricular interval: Aorta-cava: from the onset of the “A” wave on the superior vena cava to the onset of the aortic wave.
48 POSTGRADUATE DEGREE IN FETAL CARDIOLOGY MODULE 6 Total 9 images x 3 patients = 27 images RIGHT CARDIAC FUNCTION 2D-ECHOCARDIOGRAPHY 49. Right ventricle Fractional Area Change (FAC): end-di- astolic area. Value and z-score. FAC = (end-diastolic area – end-systolic area)/end-diastolic area * 100. 50. Right ventricle Fractional Area Change (FAC): end-systolic area. Value and z-score. FAC = (end-dias- tolic area – end-systolic area)/end-diastolic area *100. PULSED-DOPPLER 51. Tricuspid flow: E/A velocities. Value. 52. Tricuspid flow: filling time fraction (FTF). Value and z-score. FTF = filling time/cycle time)*100
49 53. Pulmonary flow: Systolic peak velocity. Value. 54. Pulmonary flow: ejection time fraction. Value and z-score. ETF = ejecting time/cycle time)*100 55. Ductus arteriosus pulsatility index: Value and z-score. 56. Ductus venosus pulsatility index: systolic, early diastolic and atrial contraction velocities. Values.
50 POSTGRADUATE DEGREE IN FETAL CARDIOLOGY M-MODE 57. TASPE: Tricuspid annular plane systolic excursion. Value and z-score. MODULE 7 Total 10 images x 3 patients = 30 images RIGHT CARDIAC FUNCTION PULSED-DOPPLER: 58. Mitral flow: E/A velocities. Value.
51 59. Mitral flow: filling time fraction. Value and z-score. FTF = filling time/cycle time)*100 60. Aortic flow: systolic peak velocity. Value. 61. Aortic flow: ejection time fraction. Value and z-score. ETF = ejection time/cycle time)*100
52 POSTGRADUATE DEGREE IN FETAL CARDIOLOGY 62. Myocardial performance index: isovolumic contrac- tion, ejection and isovolumic relaxation times. Value and z-score. MPI = isovolumetric contraction time + isovolumetric relaxation time)/ejection time. 1. 1. Aortic Aortic isthmus isthmus pulsatility pulsatility index: index: Value Value and and z-score. z-score. 63. Aortic isthmus pulsatility index: Value and z-score. 64. Pulmonary veins flow: systolic, early diastolic and atrial contraction velocities. Values. M-MODE 65. MASPE: Mitral annular plane systolic excursion. Value and z-score.
53 66. Left ventricle ejection fraction (EDV = (7/(2.4/EDD)) xEDD3) y systole (ESV = ((7/(2.4/ESD))xESD3): Ejection fraction = (EDV – ESV)/EDV. (EDV: end-diastolic vo- lume, ESV: end-systolic volume, EDD: end-diastolic dimension, EDS: end-systolic dimension. 67. Left ventricle shortening fraction: Value. Shortening fraction = (End-diastolic dimension – End-systolic di- mension)/End-diastolic dimension * 100.
54 POSTGRADUATE DEGREE IN FETAL CARDIOLOGY MODULE 8 BLOC 1 and 2 Total 2 clinical cases of CHD. The cases must be well documented ichnographically. The diagno- sis must be justified by showing the specific key-points of the cardiac defect. In addition, the complementary tests carried out and the summary of the antenatal advice recom- mended to the pregnant woman must be also explained. Module 9 Total 1 clinical case of CHD. The case must be well documented ichnographically. The diagnosis must be justified by showing the specific key-points of the cardiac defect. In addition, the complementary tests carried out and the summary of the antenatal advice recommended to the pregnant woman must be also explained.
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57 5. FACE TO FACE PERIOD IN BARCELONA 5 FACE TO FACE PERIOD IN BARCELONA
59 5 FACE TO FACE PERIOD IN BARCELONA The face-to-face period consists of two weeks in Barcelona (two periods of one week each). A visit to the Fetal Cardiology Unit of Hospital Sant Joan de Déu in BCNatal (Center for Maternal-Fetal and Neonatal Medicine Barcelona) will be included. The first week will take place halfway through the course in order to expand knowledge, improve skills on ec- hocardiography and facilitate interaction with mentors, faculty members and colleagues. The second week is scheduled at the end of the postgraduate to consolidate knowledge and improve understanding on novel or more advanced techniques. First week calendar: October 18-24 2021 and second weeks: March 7-13 2022. During these two periods the participants will have the opportunity to meet the faculty and their mentors. The stays will include the following activities: * “Meet the professor” sessions that enable personal discussion on the most relevant aspects of each module, based on clinical cases, with the faculty members. * Invited lectures from international experts on a specific topic of interest including basis of fetal cardiac magnetic resonance, core aspects on the assessment of the right ventricle, electrocardiogram, genetics in CHD, impact of CHD on neurodevelopment, fetal-neonatal transition and fetal cardiac programming. This will enable interaction with the postgra- duate faculty members and also with invited professors from other universities experts in a specific topic of interest. * Practical training. Dedicated sessions with volunteer patients, with hands-on fetal ec- hocardiography with reduced number of attendees, enabling to teach tips and tricks for both structural and functional echocardiography. * Workshops on 4D-STIC, strain quantification and 3D printed models of the heart to gain advanced knowledge on particular cases of CHD. * Specific meet with the mentor sessions in order to discuss any doubt on specific topics and to define and plan the research work (fist onsite week at mid-course). * Defense of the research work, enabling the discussion with colleagues and the faculty members (second onsite week at the end of the postgraduate).
61 6. RESEARCH PROJECT (MODULE 10) 6 RESEARCH PROJECT (MODULE 10)
63 6 RESEARCH PROJECT (MODULE 10) The postgraduate training includes the completion of a research work that will be evalu- ated by the Academic Committee. The research work usually includes a critical literature review of a specific topic that can be complemented by original data from the student’s institution. The research work is conducted personally by the student, under the guidance and supervision of a mentor. The topic is chosen and planned during the first onsite week and defended at the second onsite week. PRESENTATION & FORMAT Deadline and submission method: The deadline for the project’s submission will be during the last on-site week (March 7-13, 2022). The project must be submitted through the virtual campus in a PDF format. A specific “TASK SUBMISSION” will be enabled to upload it. Failure to submit it within the prescribed time limit means suspending the task. In case of requesting deferment of delivery, for any justified reason, 2 points (about 100) will be deducted, for each day of delay in delivery. FORMAT: The text must be formatted with 1.5 line spacing, Arial font, and size 12. a) Margins: The margins must be set to: Upper: 2 cm. Lower: 2 cm. Left: 4 cm. Right: 2 cm. b) Page numbering: Starting with the introduction, all pages must be numbered on the top-right side. c) Tables: They must be clear, numbered with Arabic numerals in relative order, titled cle- arly stating their content, be self-explanatory and avoid duplicating content in the text. d) Graphs: They must be clear, numbered with Arabic numerals in relative order, titled clearly stating their content, be self-explanatory and avoid duplicating content in the text or tables. e) Figures: They must be numbered with Arabic numerals in a relative order and have a short title. If the image or the photo has been published previously, the origin must be mentioned in the title with appropriate citation of the reference.
64 POSTGRADUATE DEGREE IN FETAL CARDIOLOGY CONTENTS OF THE RESEARCH PROJECT 0. COVER 1. INDEX 2. ABSTRACT 3. STATE OF THE ART – INTRODUCTION 4. HYPOTHESIS AND OBJECTIVES 5. MATERIALS AND METHODS 6. RESULTS 7. DISCUSSION 8. CONCLUSIONS 9. REFERENCES 10. ANNEXES AND APPENDICES GUIDELINES FOR DEVELOPMENT OF THE RESEARCH PROJECT 1. SUMMARY It must be written in English. It must demonstrate in a concise way the hypothesis and the obtained results. The abstract must have a maximum of 350 words and be written in a structured format including the following parts: • Introduction: Define the problem and the aim of the project. • Materials and methods: Describe how the project was done. • Results: Describe briefly the main results of the project. • Conclusions: Report the main findings of the results and the clinical implications, if relevant.
65 2. THEORETICAL FRAMEWORK This section contextualizes the project developed within the current framework of knowledge. It must be less than 10 pages long. It must clearly establish the problem being investigated, the current knowledge about it and the motivation for further research. It must summarize the relevant previous studies carried out on the subject and explain how this project is different from the prior. The theoretical framework must be strongly supported by recent scientific literature (preferably no older than 10 years). 3. HYPOTHESIS AND OBJECTIVES A short affirmative sentence that could be accepted or rejected in an experimental or a clinical research. • General objective: It must start with an infinite verb (To determine..., To analyze..., To know...) and it must be written in a way that implies the steps needed to prove the proposed hypothesis. • Specific objectives: They must be numbered according to the stages of the project. They must be written as actions that, when executed consecutively, will allow the different stages of the project to be carried out, with the aim of accepting or rejec- ting the hypothesis of the project. 4. MATERIALS AND METHODS This section must be written in the past tense, indicating: • Type of study: experimental, descriptive, prospective, etc. • Sample: Detailed description of the study sample, how it was obtained, source, characteristics, size, etc.
66 POSTGRADUATE DEGREE IN FETAL CARDIOLOGY • Procedures: The methods and procedures must be clearly described. The measure- ment instruments (if any) must be included as annexes at the end of the project. If methods or techniques from other authors have been used, they must be described briefly with the citation of the corresponding reference. It must be clearly stated how each of the specific objectives will be carried out. If applicable, this section of the project must also include an explanation of the statistical approach used to analyze the data, as well as the software used for such purpose. 5. RESULTS The research findings must be written in an objective and clear way, ideally following the order of the specific objectives and methodology. The data must be analyzed in tables, graphs, figures or images. Each of them must include an explanatory text. This section must not include the interpretation of the results, this will appear in the discussion section. When the research project compares original results with the results of other authors, the source of the compared data must be clearly explained. When a statistical analysis is included, the results must clearly state which variables are statistically different. 6. DISCUSSION This section describes the meaning of the obtained results, in the context of what is known about the studied topic. The proposed hypothesis must be discussed and accepted or rejected. Emphasis should be given to the new and important findings of the study. The research findings must be compared with previously published studies. The limitations of the experimental methods must be discussed, as well as the possible implications for future studies. When appropriate, the clinical relevance of the results must be included.
67 7. CONCLUSIONS The conclusions must be written as a series of short sentences, based directly on the obtained results and the experimental or clinical evidence of the project. Speculation from other projects must be avoided. 8. REFERENCES Citations and references must follow Vancouver style. 9. ANNEXES AND APPENDICES All the documents that are considered relevant for the research project must be included in this part. They should be cited in the text in the corresponding section and proper- ly numbered.
69 7. EVALUATION CRITERIA 7 EVALUATION CRITERIA
71 7 EVALUATION CRITERIA The evaluation of the postgraduate degree in Fetal Cardiology is based on a continuous evaluation. In order to obtain the final degree, all the parts must have been passed separa- tely (theoretical exams, practicum, clinical cases, research project, participate in the forum and final exam) within the agreed dates. Failure to comply with this rule for whatever reason involves suspending the degree. Resits: There will be only one opportunity to resit failed modules or tasks. The maximum grade that can be obtained in resits will be the minimum grade set as required to approve. This regulation does not allow exceptions of any kind. The non-approval of a module means the failure to obtain the course degree. The pos- sibility of enrolling in the next year of the pending module(s) is offered, provided that the number of modules suspended is not greater than two but requires payment of the module and all corresponding university fees. In the event of suspending more than two modules there will be no option to recovery, and you would have to enroll in the Training Course again and complete it in full. The different evaluable points of the course are described below: ONLINE EXAMS OF THE THEORETICAL MODULES The aim of these exams is to explore the level of knowledge acquired in relation to the con- tent explained in the theoretical classes. They consist of multiple-choice questions test with only one valid answer per question. The different exams are composed of 15 questions. Minimum Score: The minimum score to pass the self-assessment exams is 70%. Duration: There is a time limit of 5 hours per exam. Time starts counting at the moment of accessing the test and continues to progress despite disconnecting from the application.
72 POSTGRADUATE DEGREE IN FETAL CARDIOLOGY The test can be repeated 5 times with a time interval between attempts of 4 hours. Despi- te having passed the exam, it can be repeated in order to continue learning and improving the obtained score. The system will consider the best score among the attempts. The average score of all the self-assessment exams of the different modules will have an impact on the overall score of the course contributing by 25%. It is necessary to pass each module to be able to calculate the average. The exam must be carried out during the time period defined in the Virtual Campus. The time used for the submission deadlines will be Spanish time zone (GMT +1). PRACTICUM The images of the practicum must be submitted within the requested deadlines in order to be evaluated. To obtain the final postgraduate degree this part must be passed. Any submission after the deadline will entail the non-evaluation of the practicum and will be considered as failed. There will be a recovery period at the end of the postgradu- ate degree. The students will have a calendar with the practicum’s submission deadlines of the prac- ticum’s, the recovery deadlines and the expected dates to receive the practicum scores from the teaching staff. The final score of the practicum will be obtained by calculating the average of the 9 sub- missions and will correspond to 25% of the overall score. Resits: There will be a second opportunity to resubmit any failed practicum, either for not having submitted it prior to the deadline or for not having reached the necessary score to pass. The maximum score that can be obtained in the recovery will be 70%. If the student fails the resit, there will be no more chance of resubmission, and therefore, it will not be possible to obtain the final certificate of the ‘postgraduate degree in Fetal Cardiology.
73 Deferrals: If the student is unable to submit a task of a module, always before the stated date, an extension can be requested by filling out a form available on the virtual campus for consideration by the teaching coordinator. Extensions of deadlines will only be accepted for larger and justifiable reasons. RESOLUTION OF CLINICAL CASES, FORUM CONTRIBUTION AND MASTERCLASSES The participation in the forum will be evaluated continuously throughout the course. Those contributions that provide answers to the questions raised in the clinical cases and the doubts generated by the rest of the participants will be positively valued. This part represents 10% of the final score. RESEARCH PROJECT To obtain the final postgraduate degree this part must be passed and it will correspond to 20% of the overall score. To set the final project score, the evaluation criteria described above will be followed. To approve the final project, a minimum grade of 7 will be required. • Evaluation criteria (Maximum score): • RELEVANCE OF THE PROPOSAL: Is the developed project relevant? 0,5 • ORIGINALITY OF THE PROPOSAL: Is the developed research project original? 0,5 • DRAFTING OF THE PROJECT: Is the project WELL written and follows the scien- tific standards? 1 • OBJECTIVES: Are the objectives clearly defined and stated? 0,5 • HYPOTHESIS: Is the hypothesis clearly established? 1 • MATERIALS AND METHODS: Are the methods used in the development of the project appropriate? 1 • RESULTS: Are the data properly and clearly presented? 1
74 POSTGRADUATE DEGREE IN FETAL CARDIOLOGY • DISCUSSION: Are the obtained results critically analyzed? Are they properly com- pared to the existing literature on the topic? 0,75 • CONCLUSIONS: Are the conclusions based on scientific evidence? 0,5 • REFERENCES: Are the project references written correctly? Are the references updated and relevant to the subject? 0,25 • TOTAL SCORE: 10 FINAL EXAM The aim of the final exam is to explore the level of knowledge acquired in the postgraduate degree. It will correspond to 20% of the overall score. It consists of 50 multiple-choice questions test with only one valid answer per question. Minimum Score: The minimum score to pass the self-assessment exams is 70%. Duration: There is a time limit of 2 hours. Time starts counting at the moment of acces- sing the test and continues to progress despite disconnecting from the application. The test can be repeated 5 times with a time interval between attempts of 4 hours. Despite having passed the exam, it can be repeated in order to continue learning and improving the obtained score. The system will consider the best score among the attempts. The exam must be carried out during the time period defined in the Virtual Campus. The time used for the submission deadlines will be Spanish time zone (GMT +1).
75 FINAL EVALUATION Average of the module’s exams 25% Average of the practicum 25% Clinical cases and Forum contribution 10% Research project 20% Final exam 20% TOTAL 100% GRADING Score Grade Comment 0 – 6.9 Fail 7 – 7.9 Approved 8 – 8.9 Very good 9 – 10 Excellent The top two overall scores (as long as they are above 9) will be graded with an honor mention. DEGREE The students will be awarded two certificates: 1. A university “Postgraduate Degree in Fetal Cardiology”. The title will be issued by the Institute of Continuing Education (IL3) of the University of Barcelona. 2. Certificate in Fetal Cardiology from the I+D Education Barcelona.
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