Lower back pain: Global burden of disease and community-based care
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Lower back pain: Global burden of disease and community-based care Associate Professor Fiona Blyth MBBS (Hons) FAFPHM, PhD Discipline of Pain Medicine & Sydney School of Public Health University of Sydney
Overview of talk Overview of GBD 2010 background and methods Results for the burden of disease from low back pain globally and in Australia Other Australian data on the population impact of back pain
GBD 2010 O Overallll Ai Aims To produce new new, robust robust, and reliable estimates of burden for all major diseases, injuries and risks that are widely injuries, disseminated, understood, and easily used by policymakers, researchers, funders, f and practitioners. p
Why now? Changing global demography Changing global economy Changing patterns of disease and di bilit disability eed for Need o a comprehensive co p e e s e a andd syste systematic at c revision of global burden of disease estimates
GBD 1990 and onwards GBD 1990 began in 1991, first estimates in the World Development Report in 1993, final estimates published in 1996 1996. Collaboration of Harvard University, World Bank and World Health Organization. Organization 107 Diseases and Injuries, 10 Risk Factors, F Forecasts t to t 2020 2000- 2000-2004 WHO produced updates; ongoing methodological th d l i l enhancements h t GBD 2010 underway since 2008 (>175 diseases and d iinjuries, j i 20 risk i k ffactors) t )
GBD 2010 globalburden.org Key collaborators: Johns Hopkins University Harvard University University of Queensland Institute for Health Metrics and Evaluation at the University of Washington World Health Organization
Global Burden of Disease Organizational Structure More than 480 experts globally Core Team External Advisory Board participated in GBD 2010 Tools and Curricula Development Sub- Team Mortality Cause of Death Disability Weights Comparative Risk Estimation Sub-Team Sub-Team Sub-Team Sub-Team Alan Lopez and Josh Salomon and Majid Ezzati Ken Hill and Chris Murray Colin Mathers Kenji Shibuya Cluster A: Cluster B: Cluster C: Cluster D: Cluster E: CVD, COPD, Cancer Child/Maternal Injuries and Mental Health Communicable Diseases Noncommunicable Diseases Majid Ezzati Bob Black Theo Vos Neff Walker Catherine Michaud Harvard University Johns Hopkins University University of Queensland Johns Hopkins University Harvard University Expert Groups: Expert Groups: Expert Groups: Expert Groups: Expert Groups: Air Pollution (Risk) ARI Meningitis Sepsis Alcohol (Risk) Hepatitis Anemia Cancers Child Nutrition (Risk) Childhood Sexual Abuse (Risk) HIV/AIDS Dental Health CVD and Related Risks Congenital and Neonatal Mental Disorders Other Infectious Diseases Diabetes Global Climate Change Enteric Infectious Disease Musculoskeletal Other Parasitic and Vector Diseases Digestive Disease Respiratory Disease Maternal Conditions Neurological Conditions STDs Endocrine Disorders Tobacco (Risk) Malaria Occupational Risks (Risk) Tuberculosis Genitourinary Other Childhood Diseases S i id Suicide Skin Diseases Unintentional Injuries Traffic Injuries War and Civil Conflict Vision and Hearing
Musculoskeletal conditions in GBD: evolution over time • Osteoarthritis (GBD 1990, 2000, 2010) • Rheumatoid eu ato d a arthritis t t s (G (GBD 1990, 990, 2000,2010) 000, 0 0) • Low Back pain ( LBP in GBD 2000, 2010) • Neck Pain (GBD 2010) • Gout (GBD 2010) • Other MSK (GBD 2010)
Low Back Pain: the old GBD Model (GBD2000) LBP resulting in limitations on usual activities activities, Duration=4 days, no mortality Acute ((
Low back pain: the new GBD model Based on extensive systematic review of the literature Had to be consistent w natural history of LBP Major constraints on how health states could be described
New definition Case d C definition: fi iti A Activity-limiting ti it li iti lowl b backk pain i ((+/-pain / i referred f d to one or both legs) that lasts for at least one day. Low back=area Lo back area on the posterior aspect of the bod body from the lower lo er margin of the 12th ribs to the lower gluteal folds Acute/subacute < 3mths; Chronic 3 mths or more
How would you describe these low back pain health states so that they p y could be understood by ‘lay people’ in different communities and countries around the world? How would you do this for f all the different ff diseases in GBD 2010?
Building a lay description from the Health State Checklist The first set of questions asks about capacity along several dimensions of functioning. Indicate by checking either ‘yes’ or ‘no’ whether a person would be able to perform the following functions. Rising: g Rise from lying y g position p on the ground g (Yes/No); ( ); Rise from sitting position on the ground (Yes/No)
Building a lay description from the Health State Checklist The second Th d set off questions i asks k about b specific ifi symptoms t or problems. Indicate by checking either ‘yes’ or ‘no’ whether a person would experience the symptom or problem, and indicate average duration and/or frequency where relevant Feeling worried or anxious (Yes/No; # days per week;# hours per day)
Quite a process! Final versions had to be concise Modified after feedback from GBD central team which had oversight of all disease groups Major restrictions on both l length th and d content t t Why? GBD is a RANKING exercise
The final lay descriptions descriptions... ACUTE BACK PAIN WITH LEG PAIN - “person with severe back and leg pain” This person has severe back and leg pain, which causes difficulty dressing sitting dressing, sitting, standing, standing walking, walking and lifting things things. The person sleeps poorly and feels worried. CHRONIC LOW BACK PAIN WITH LEG PAIN - “person with constant back and leg pain” This person has constant back and leg pain, which causes difficulty dressing sitting dressing, sitting, standing, standing walking, walking and lifting things things. The person sleeps poorly, is worried, and has lost some enjoyment in life.
Prior GBD estimates used disability weights based on valuations f from h lth professionals health f i l only l (?h (?how accurate) t ) Last GBD round, musculoskeletal conditions assigned low disability weights→low ranking This time: community surveys as well as health professional surveys in different countries – asking a broader range of people to assess disability
Overview of talk Overview of GBD 2010 background and methods Results for the burden of disease from low back pain globally and in Australia Other Australian data on the population impact of back pain
‘Democratization Democratization of data’ data International launch of results in triple issue of The Lancet in London (13( December 2012) Open access data visualisation tools rapidly made available on Institute of Health Metrics Evaluation website: http://www.healthmetricsandevaluation.org /gbd/visualizations/country
htt // http://www.healthmetricsandevaluation.org/gbd/visualizations/country h lth t i d l ti / bd/ i li ti / t
http://www.healthmetricsandevaluation.org/gbd/visualizations/gbd-arrow- htt // h lth t i d l ti / bd/ i li ti / bd diagram
http://www.healthmetricsandevaluation.org/gbd/visualizations/gbd-cause- htt // h lth t i d l ti / bd/ i li ti / bd patterns
Musculoskeletal conditions Widespread recognition of the huge disability burden globally and within Australia related to MSK conditions (NB low back pain and neck pain) Surprisingly low disability weights for osteoarthritis Significant gaps in basic data from many countries Lack of consistent data to be addressed in the future (eg, (eg severity and length of episodes of LBP or neck pain)
Overview of talk Overview of GBD 2010 background and methods Results for the burden of disease from low back pain globally and in Australia Other Australian data on the population impact of back pain
Australia’s Health 2012 Report (Australian Institute of Health and Welfare): People with living with disability (minimum 6 months duration, restricting everyday activity)
Australia’s Health 2012 Report (Australian Institute of Health and Welfare): Health service use for MSK conditions GP management: medications medications, imaging,referrals, advice about self-management ?other primary care ? Risk assessment/stratification
Key findings Working age people with long-term back problems were more than two and a half p times more likely not to be in the labour force With three or more additional conditions, this goes up substantially – more than nine y not to be in the labour times more likely force Early retirement due to back problems will substantially reduce accumulated wealth
Conclusion A clearer picture is emerging of the heavy global and national toll of low back p g pain (and other MSK conditions) Important that it is used to argue for resources Also important to keep up the ‘back room’ efforts to improve how this burden is measured
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