Light - The Science Magazine of the Max Planck Society 2.2015 - Dreams Bring Lucidity to Our Thinking - Max-Planck-Gesellschaft
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B56133 The Science Magazine of the Max Planck Society 2.2015 Light COGNITION COMMUNICATION EARTH SYSTEM RELIGION Dreams Bring Lucidity Secret Code … and now for A Crucial Question to Our Thinking in a Laser Pulse tomorrow’s climate for the Nation State
www.siemens.com/pof Scenario 2040 — in Antarctica: Smart grids are applying digital intel- ligence to energy supply systems. Even in places far from civilization, the grids ensure network stability and balance out power generation and consumption. Pictures of the Future The Magazine for Research and Innovation Which technologies will shape our lives in the decades ahead? The online magazine Pictures of the Future reports on the most important trends in technology and offers insights into the laboratories at Siemens. It designs future scenarios, describes exciting research activities in feature stories, reports and interactive 360° features, and provides a platform for experts from all over the world. www.siemens.com/pof You can find more information about smart grids at: www.siemens.com/pof/smart-grids
ON LOCATION Photo: MPI for Chemical Ecology/Anna Schroll Eternal Summer Even on cloudy days, the sun shines in the greenhouse of the Max Planck Institute for Chemical Ecology: 520 high-pressure lamps with assimilation sodium vapor bulbs ensure that the plants have sufficient light and that the spectral distribution is right for photosynthesis. To simulate uniform irradiation, the lamps move back and forth automatically on tracks. The air conditioning is also computer controlled: temperatures remain at summer levels – but not too high – all year round. Half of the 474-square-meter cultivation floor is usually sown with coyote tobacco (Nicotiana attenuata), a species of wild tobacco and the institute’s most important model plant. Along with rapeseed and pea plants and poplars, the greenhouse also boasts some more exotic inhabitants: pest-resistant bananas, noni trees and carnivo- rous pitcher plants. The latter are the main focus of interest for researcher Ayufu Yilamujiang. He studies the exact composition of the digestive fluid with which the plant digests the trapped insects. Carnivorous plants grow in low-nutrient soils and obtain additional nutrition from their animal prey, mainly insects. To this end, they have developed special trapping and digestive mechanisms. In the case of the pitcher plant, sweet nectar lures the insects to the edge of the pitcher, which is basically formed from reshaped leaves. The animals slip off the edge of the pitcher and fall into the digestive fluid. The pitcher plants also find the occasional prey in the greenhouse, as parasites or beneficial organisms used to combat these – ichneumon wasps, for instance – occasionally fall victim to them. For experiments carried out under controlled conditions, the scien- tists feed the pitcher plants with fruit flies. 2 | 15 MaxPlanckResearch 3
Contents Complicated: Jens Hjörleifur 18 LIGHT 46 Bárðarson focuses on, among other things, topological insulators. 18 Tweezers Made of Light PERSPECTIVES Many biomolecules move through cells like microscopic machines. 06 Cooperation Worth Celebrating Often, however, it isn’t known what forces these molecules generate or how fast the molecules act or move. That’s why Stephan 06 Green Light for Research Projects Cover: iStockphoto – merrymoonmary; photos this page: Thorsten Naeser (large image), Sven Doering Grill from the Max Planck Institute of Molecular Cell Biology and 07 The Max Planck Society Researches Genetics in Dresden decided to specialize in measuring molecular Its Own History forces. He uses optical tweezers to pull gently on DNA strands and 07 Max Planck Spinoff Finds Buyer to study proteins. with Deep Pockets 08 “It’s not surprising that the fear 24 The Making of a Quantum Movie was palpable” Until even just a few years ago, no camera was fast enough to film 09 New Internet Presence for the movements of electrons. Ferenc Krausz, Director of the Max max-wissen.de Planck Institute of Quantum Optics in Garching, and his team can now do this using new techniques, creating the basis for optimizing 09 On the Net processes in chemistry and electronics. 32 Between Spotlight and Shadow VIEWPOINT The main figures in Caravaggio’s paintings seem to be sitting 10 Peace – Europe’s Polyphonic in a spotlight. There were numerous legends surrounding the Promise painter and his lighting techniques. Sybille Ebert-Schifferer, In view of the challenges to Director at the Bibliotheca Hertziana in Rome, wants to demystify peace and security in Europe, Caravaggio’s image. it’s time for EU member states to take joint action. FOCUS 18 Tweezers Made of Light ON THE COVER Light is our lifeblood, the inspiration for artists, and an indispensable tool in science and technology. Reason enough for UNESCO to declare 2015 the Inter- 24 The Making of a Quantum Movie national Year of Light. The image shows light in optical fibers. 32 Between Spotlight and Shadow 4 MaxPlanckResearch 2 | 15
Concealed: Magnetic resonance Encrypted: The quantum Swirled: Ocean currents such as 52 imaging makes visible which brain regions are active in lucid dreamers. 60 information receiver that can’t be tapped unnoticed. 68 the Gulf Stream play a major role in the climate. SPECTRUM BIOLOGY & MEDICINE CULTURE & SOCIETY 40 Listen Carefully 52 Dreams Bring Lucidity to 76 A Crucial Question for the 40 Mars – The Blue and Red Planet Our Thinking Nation State 41 Nature’s Medicine Cabinet “I think, therefore I am” – René While Islam is still perceived by Descartes’ thinking gave him the many as the greatest impediment to 41 Food in Tubes certainty that he did, in fact, integration in European immigration 41 By Computers, for Computers exist. Lucid dreamers are able to societies, scientists have come up 42 World Record in Color reflect on their own thoughts with a more differentiated approach. 42 Ceres – A Mysterious World even during sleep. Photos: David Ausserhofer, Axel Griesch, DKRZ – Michael Böttinger (left to right) 43 Babies Learn while Snoozing REGULAR FEATURES 43 Poison Sprays Return to Haunt Us MATERIAL & TECHNOLOGY 44 Language Roots on the Steppe 03 On Location 44 Solving the Puzzle of Nova Vul 1670 60 Secret Code in a Laser Pulse 16 Post from – London, England 45 Using Nuclear Spin to Study Quantum cryptography aims to Immediate Inspiration Individual Proteins protect data transmissions against 82 Flashback eavesdropping. This is what Strawberry Fields Forever 45 Customized Carbon researchers from the Max Planck 45 Learning with All the Senses 84 Community Institute for the Science of Light 84 “A Win-Win Situation” are working on. 85 New Content Leads to New Horizons PHYSICS & ASTRONOMY 86 50 Million Euros for Junior Scientists ENVIRONMENT & CLIMATE 87 Research Establishments 46 Player in a Magical World 87 Imprint Personal Portrait: 68 … and now for tomorrow’s climate Jens Hjörleifur Bárðarson Researchers want to predict what the Earth’s climate will be like 10 or 15 years from now, and in this way also explain why, since 1998, the Earth has been heating up more slowly than models predict. 2 | 15 MaxPlanckResearch 5
PERSPECTIVES Photos: Amac Garbe/MPG (top), MPI for Molecular Cell Biology and Genetics, Katrin Boes, Max-Planck-Campus/Tübingen, fotostudio arlene knipper, private collection, MPI for Human Cognitive and Brain Sciences, private collection (bottom, from left to right) Cooperation Worth Celebrating Science celebrates 50 years of German-Israeli relations Half a century has passed since Germany and Israel established diplo- matic relations. To mark this anniversary, scientists from both coun- tries, the presidents of leading research organizations, and political guests met in Israel for a two-day celebration. The event was co-orga- nized by the Minerva Stiftung, a subsidiary of the Max Planck Society that is financed by the Federal Ministry of Education and Research and that has been promoting scientific cooperation between the two coun- tries since 1964. “I firmly believe that nobody could have predicted such a development 50 years ago,” said Max Planck President Martin Stratmann, stressing that “in view of our particular history, promoting mutual understanding remains an important task.” The high point of the celebrations was a scientific symposium held at the Weizmann Institute of Science in Rehovot and officially launched by the German Federal Minister of Education and Research, Johanna Wanka. The Minister also inaugurated two new Minerva Research Cen- ters, bringing the total to 23 of these centers of excellence in Israel. “The Minerva Centers are the jewel in the crown of German-Israeli sci- entific relations. They have also become an important feature of the Israeli research landscape,” said Johanna Wanka. In his speech at the anniversary celebrations, Max Planck President Stratmann emphasized the unifying nature of science: “People from different countries can meet on neutral ground, so to speak, in scientific institutions.” This was also the basis for German-Israeli scientific relations, which have existed now for more than 55 years. Green Light for Research Projects Max Planck scientists attract EU millions for their projects The 328 junior scientists awarded institutes also competed successfully in their applications for the funding of Starting Grants by the European Re- for ERC Consolidator Grants. The projects with partners from Bulgaria, search Council (ERC) last December Teaming funding line is a new element Poland and Cyprus. include 17 Max Planck scientists. The of the “Horizon 2020” EU Research funding of up to two million euros al- Framework Programme, which links The Max Planck scientists recently awarded located to the 17 Max Planck research- renowned research institutions with Consolidator Grants (from left): Jochen Rink ers is intended to help them with the institutes in regions that perform less and Jan Huisken (molecular cytology and genetics), Birte Höcker (developmental development of independent scientif- strongly in the area of research. The biology), Sönke Zaehle (biogeochemistry), ic careers in the period immediately Max Planck Society played a key role Mikael Simons (experimental medicine), following their doctoral studies. A fur- in the design of this instrument. Four Jonas Obleser (cognitive and neurosciences) ther seven scientists from Max Planck Max Planck institutes were successful and Henrik Beuther (astronomy). 6 MaxPlanckResearch 2 | 15
PERSPECTIVES The Max Planck Society Researches Its Own History Seven-year program focuses on the organization’s development Over the next seven years, a research program at the Max Planck Institute for the History of Science will examine the development of the Max Planck Soci- ety from its foundation in 1948 to the end of Hubert Markl’s presidency in 2002. The program is intended to in- vestigate the organization’s dynamics and research successes, as well as its sci- entific dead ends, which, however, of- ten proved productive in the final anal- ysis. The program will also concentrate on critical topics like the ethical limits of research, the dual-use problem and external influences. Building on the studies on the Kaiser Wilhelm Society during the National Socialist period, the scientists also intend to take a fresh look at how the Max Planck Society dealt with the misconduct of its prede- cessor organization. The research program, whose par- ticipants include renowned external The history of the Max Planck Society began in 1948. The inaugural meeting took place in the canteen of the Institute for Aerodynamic Testing (Aerodynamische Versuchsanstalt) in Göttingen. scholars, aims to comprehensively re- construct the past and classify it in terms of the relevant historical con- stitution’s research and development view to its position in science, society texts. Based on the example of several mutually influenced each other. The fo- and politics. The research program will inter-institutional topics, the historians cus here is on the changes of the Max be supervised by an international sci- wish to concretely examine how the in- Planck Society through time with a entific advisory board. Max Planck Spinoff Finds Buyer with Deep Pockets US concern Baxter takes over biotech company SuppreMol How the knowledge gained through ba- pany, which has 20 employees, made it so agency supported the development of sic research stimulates the economy was attractive that US pharmaceutical con- SuppreMol, particularly in the company’s demonstrated by the sale of SuppreMol cern Baxter was willing to pay over 200 pre-spinoff and early phase. The fact that GmbH in March: Established in 2002 by million euros for it. SuppreMol succeeded in attracting a scientists working with Nobel laureate “This was one of the biggest transac- strong owner like Baxter for the expen- Robert Huber from the Max Planck Insti- tions in the sector, which has been expe- sive clinical development and market tute of Biochemistry in Martinsried, the riencing funding difficulties, particularly preparation of its drugs has been warm- Photo: Amac Garbe/MPG biotech company carries out research on in Germany, for years,” says Ulrich Mahr, ly welcomed. The Max Planck Society and innovative drugs for the treatment of au- a member of the management team of the Max Planck Institute will also benefit toimmune diseases such as multiple scle- Max -Planck-Innovation GmbH. The Max from the sale and stand to receive sums rosis. The advances achieved by the com- Planck Society’s technology transfer in the lower single-digit million range. 2 | 15 MaxPlanckResearch 7
PERSPECTIVES “It’s not surprising that the fear was palpable” Anita Schroven from the Max Planck Institute for Social Anthropology is still helping to manage the Ebola crisis in West Africa Where do you get your information from? things that the locals didn’t understand and I am in contact with acquaintances involved presenting a risk scenario that didn’t en- in field research, and follow reports on the courage cooperation – especially as there radio and Internet. I also maintain contact were huge information campaigns convey- with experts in the field – anthropologists ing the message that there is no cure or and other social scientists involved in fight- treatment for Ebola. ing the Ebola outbreak and working with the WHO, Médecins Sans Frontières, the But people realized that this approach Red Cross and the UN mission, as well as the wouldn’t achieve the desired results – network to which I belong. We debate spe- or did they? Anita Schroven cialist issues and can pass on research find- Yes, first of all, the communication was im- ings about local practices. proved. Instead of sending representatives When field researchers aren’t out in the from central government, local dignitaries field, they have no problem participating in You carried out research in Guinea on ideas were involved. Village elders, religious lead- the unfolding events from their desks at and practices of state and statehood in the ers and leaders from the initiation societ- home thanks to technology. Anita Schrov- local context. Are there links between this ies lend greater legitimacy to such process- en, an academic staff member in the “Inte- and Ebola? es. Secondly, consistent use was made of gration and Conflict along the Upper Guin- The question as to the extent to which the the media; discussion forums in which peo- ea Coast (West Africa)” research group, is in population can trust state structures aris- ple could participate by cell phone were contact with Guinea. She lived in the West es in Guinea, in particular. This has a lot to transmitted on the radio. Moreover, it was African country for one year. As is the case do with the history of the country, which essential to ensure that the information is in neighboring Sierra Leone and Liberia, gained independence in 1958 but was then available in the local languages. the threat of new Ebola infections hasn’t governed by two dictators for 50 years. The been entirely eliminated there. political arena has become increasingly Was at least the initial medical position clear? ethnicized in recent years. The president’s Even among researchers, there was and is Out of sight, out of mind: Ms. Schroven, how group is accused of profiting more than no consensus: How reliably can the knowl- should we see the current situation in West others from the state mining revenue. edge gained from earlier outbreaks be ap- Africa from our European perspective? There’s a lot of distrust. plied? How different are the situations in Anita Schroven: The good news is coming the individual countries? Just one example: from Liberia at the moment: there have Naturally, this is disastrous in the context in Liberia, they changed the recommenda- been no new cases of Ebola there since of Ebola. tion for sexual contact for Ebola survivors March 22. Given that the incubation period The population perceives government in- from 90 days of abstinence and now advise for the disease is 21 days, this gives us cause tervention as negative, as it is often asso- people to use condoms until there is great- for hope. To be on the safe side, the World ciated with violence and corruption. Mea- er clarity on the issue. But people sit up and Health Organization (WHO) has decreed sures carried out in the areas of infrastruc- take notice when different information is that, for a country to be declared Ebola- ture, education and healthcare tend to be suddenly in circulation. They assume, for free, a period of 42 days must pass since the ascribed to international aid. The idea of example, that their own government wants last case tested negative twice. Although civil society is still a recent one in Guinea. to harm them. the number of new Ebola cases is falling in Sierra Leone, people are still contracting But comprehensive external aid was rapidly What’s next for your research? the disease and the transmission routes required for Ebola. How was that managed? We’re planning a conference in Halle in Oc- aren’t yet known. The number of new Ebo- That was a major challenge for all three tober, where the current field research will la patients in Guinea is stagnating. countries. People were used to internation- be linked with theories concerning knowl- al intervention in Sierra Leone and Liberia, edge production and translation. We want So, we can’t say that the Ebola outbreak is as both countries had been subject to UN to know which information was available coming to an end? mandates after the civil wars there. At that where and what kind of knowledge was No, unfortunately not. This isn’t the percep- time, refugee aid was provided to people disseminated, as the degree of knowledge Photo: Private collection tion on site either. People are able to move from neighboring countries in Guinea at fragmentation is very high. The complexity freely between the three countries. The the expense of the local population. So it of knowledge generation and translation border controls don’t prevent this, but they isn’t surprising that the reservations and alone can explain why, despite the informa- are having an impact on trade. Food prices fear were palpable when people wearing tion available from earlier Ebola outbreaks, are increasing and this is contributing to astronaut suits arrived, accompanied by it wasn’t possible to prevent an epidemic of an increase in hunger in the region. people from the ministry of health, saying the current scale. Interview: Susanne Beer 8 MaxPlanckResearch 2 | 15
PERSPECTIVES New Internet Presence for max-wissen.de Relaunch of the successful German-language website for students and teachers now online To mark its tenth anniversary, the German-language web- popular destination for both teachers and students. Here, site max-wissen.de has a completely new look. In addition they can access information about current research topics to the traditional “MAX-Heft” dossiers, the very latest in- and obtain more in-depth information than in standard formation, images, and now also high-quality videos can school textbooks. The material presented on max-wissen. be found there on fascinating topics from research, such as de makes the everyday lives and activities of scientists more plant immunity, stem cells, climate change and biomateri- transparent: How do researchers obtain their results? What als. The Max Planck Society launched the knowledge por- methods do they use? tal in 2005 with the help of funding from the Stifterverband The website has supplemented the published MAX se- für die Deutsche Wissenschaft. Since then, it has become a ries, BIOMAX, GEOMAX and TECHMAX, since the late 1990s. The number of orders re- ceived for these dossiers show that far in excess of 100,000 students work on content from the Max Planck Society every year. The infor- mation contained in the dossiers has even found its way into the Abi- tur, the German school-leaving ex- amination, in some federal states. Animations, video clips, the MAX series, background information and teaching support material: the max-wissen.de teacher’s portal offers up-to-date, informative and fascinating material for school classes free of charge. On the Net Our City Observing Apes on the PC The Art of Packaging in the Cell The German-American youth portal Welcome to Africa! Primate researchers We are more than the sum of our genes. “Step into German” of the Goethe Insti- from the Max Planck Institute for Evolu- Environmental factors can affect our tut familiarizes young people with mu- tionary Anthropology built camera traps chromosomes. This alters the tightness sic, film and soccer in Germany, as well in 14 African countries to record thou- of the DNA packaging – and this dic- as the German language. In the new se- sands of film sequences. The recordings tates, in turn, whether a particular gene ries “Our City,” members of the band must now be evaluated. Since April 22, can be read or not. As our new film Epi- Tonbandgerät present Hamburg and ex- the public can view the material on the genetics – Packaging Art in the Cell shows, plain where they spend their free time, new citizen science platform “Chimp & the environment can shape our charac- what they like to eat and where they go See” and in this way help the primatolo- teristics over generations in this way. shopping. This whets the appetite for a gists with their work. It is sometimes https://youtu.be/86H4olxRx7E visit to the Hanseatic city and may even the case that there is nothing to see for trigger a desire to study and live there. quite a while. Then, a warthog may www.goethe.de/ins/us/saf/prj/stg/ suddenly appear on the screen before a enindex.htm group of chimpanzees engages in some Photo: MPG leisurely grooming in front of the camera. www.chimpandsee.org 2 | 15 MaxPlanckResearch 9
VIEWPOINT_Foreign Affairs Peace – Europe’s Polyphonic Promise Brussels determines the direction in many policy fields, but in European foreign, security and defense policy, it’s the member states that set the tone – not the EU. When it comes to international peace talks or emergency meetings, such as the one held recently over the crisis in Ukraine, it’s the national foreign ministers and not the EU foreign policy chief taking the lead. However, given the challenges for peace and security in Europe, our author holds that this is an outdated model: it’s time for the member states to act in concert. TEXT CAROLYN MOSER T he hostilities in Ukraine came as a shock sis and its devastating socio-economic effects have un- to most European citizens, many of whom dermined the cohesion within the European Union, had lived their lives to date without the a war between EU member states is unthinkable. shadow of war looming over them. This In 2012, the European Union was awarded the stable and long-lasting period of peace in Nobel Prize for Peace for this great accomplishment. Europe, a continent formerly shaken by armed con- The jury’s decision can also be read as a friendly re- flict, is largely the achievement of the European in- minder to Brussels to safeguard (social) peace in times tegration process, which has succeeded in reversing of increasing internal friction. Accepting the prize, Herman van Rompuy, then President of the Europe- an Council, described Europe’s situation as follows: “Peace is now self-evident. War has become incon- War between EU member states is ceivable.” He also added words of warning whose meaning is intensified in light of the ongoing crisis unthinkable today in Ukraine: “Yet ‘inconceivable’ does not mean ‘im- possible’. And that is why we are gathered here to- the centuries-old paradigm of peace as an interlude day. Europe must keep its promise of peace.” between wars. Today, peace has become the rule in Keeping this promise is no easy task, as peace does Photo: dpa Picture-Alliance Europe, while military violence is the exception. not equate with the mere absence of war. Moreover, It seems to have been forgotten in both public per- peace depends on both internal and external dynam- ception and public opinion that the European proj- ics, which are often intertwined. In recent years, the ect has, despite its shortcomings, founded a peaceful impact on the European Union and its member states entity made of democracies built on the rule of law of external or externally influenced events has repeat- and respect for human rights. Even if the financial cri- edly become apparent. > 10 MaxPlanckResearch 2 | 15
VIEWPOINT_Foreign Affairs 2 | 15 MaxPlanckResearch 11
VIEWPOINT_Foreign Affairs The CHARLIE HEBDO attacks in Paris, in which transna- pace to move forward with integration with respect tionally acting terrorist groups were involved, are still to security, defense and foreign affairs. fresh in our memories. We have also witnessed civil Informal consultations laid the foundations for wars in Libya and Syria, leading to a considerable in- the Common Foreign and Security Policy (CFSP) in- crease in asylum seekers in European countries. Cur- troduced in 1993 by the Treaty of Maastricht, as well rently, the Union is additionally faced with war in a as for the post of High Representative for the Com- country that shares a common border with several of mon Foreign and Security Policy that was established its member states, namely Ukraine. six years later by the Treaty of Amsterdam and that These events illustrate that peace in and around was first held by Javier Solana. Europe can’t be taken for granted, and that a vari- In the wake of the Kosovo crisis – when, after the ety of security challenges lie ahead. So the time has Balkan wars, European nations were again unable to come for member states to reinforce unity in foreign properly respond to the atrocities committed in their policy, security and defense matters. While this own backyard – a Common Security and Defence Pol- might seem obvious to the reader, it doesn’t corre- icy (CSDP) was added to the CSFP in 1999. Its aim spond to reality. was to bundle resources, share expertise and increase Contrary to the motto of the Union, “United in coordination to allow for concerted action. diversity,” there is a great deal more cacophony than The CSDP went through its baptism of fire short- unity among member states when it comes to issues ly thereafter when, in 2003, the Union sent its first with foreign affairs, security and defense implica- civilian police mission to Bosnia and Herzegovina, tions. Concerted action in this area would certainly and began its first military deployment in Macedo- nia. To date, the Union has launched more than thir- ty civilian missions and military operations, varying in geographic focus (Europe, Asia, Africa) and the- 3,000 military staff are deployed in matic span. five military operations Civilian missions range from border assistance and monitoring to rule of law support, police train- ing and police capacity building to security sector re- help cope with existing and forthcoming threats to form assistance and military capacity building. Mili- stability and peace in Europe, as would a strong in- tary operations comprise training missions for armed ternational standing of the Union. forces, military advice and naval anti-piracy activi- Member states have existing structures and exper- ties, as well as combat and humanitarian tasks. To en- tise on which to build. The Union has progressively able the Union to undertake this wide array of activ- been equipped with a security and defense strand, ities, member states have progressively created which has already enabled the EU to launch a vari- Brussels-based structures vested with planning, deci- ety of civilian missions and military operations. sion-making and implementation capacities. Since 2003, thousands of civilian experts and mil- Yet, after brisk activity in the Solana era, the Com- itary staff – including judges, police officers, infantry mon Security and Defence Policy almost came to a and navy soldiers and officers, or monitors – have standstill in the wake of the financial crisis when been sent out with the Union’s flag on their uniforms member states accorded a lower profile to foreign af- and vehicles to contribute to the process of restoring fairs, security and defence policy questions at the EU stability in countries or regions shaken by crises. At level. The EU’s international standing has declined as the time of writing, some 3,000 civilians are working a result. But Brussels can’t be blamed for this deteri- in twelve civilian missions, and another 3,000 mili- oration, given that decision-making in this policy tary staff are deployed in five military operations. area rests quasi-exclusively with member states and One or two decades ago, only resolute optimists their representatives in Brussels. would have thought such united external efforts pos- The legal, institutional and procedural frame- sible. After the failure of the European Defence Com- work of the Common Security and Defence Policy munity – an ambitious project envisaging a Europe- (CSDP) and of the Common Foreign and Security an army – in 1954, member states adopted a slower Policy (CFSP) are shaped predominantly by inter- 12 MaxPlanckResearch 2 | 15
governmental features. Indicative hereof is the fact the European External Action Service (EEAS): in es- that the main actors and decision makers are the Eu- sence, the cryptic acronym stands for nothing less ropean Council (composed of heads of state and than the nucleus of an EU ministry of foreign af- government) and the Council of the European fairs. And yet, appearances matter, so the seeming- Union (constituted by representatives of member ly neutral designation EEAS was eventually chosen states’ governments). Unlike in other policy areas, the European Commission and the European Parlia- ment play only a minor role in matters related to foreign affairs, security and defence, and the Court A security strategy that combines of Justice of the European Union generally has no all elements of foreign policy jurisdiction in this field. In addition, the principle of unanimity prevails here, with some minor exceptions, in contrast to over a more political denomination (such as minis- other policy areas. All 28 member states need to be try of foreign affairs), potentially stirring up fears in consensus to define a common position or to of losing sovereignty to Brussels. launch a civilian mission or military operation. In Considering these underlying patterns, it is ap- the event of disagreement among member states, parent that there is little leeway for the Union to re- the EU’s security and defense are paralyzed. This has act to external threats. Faced with civil wars across repeatedly happened in crisis situations – the Arab the Mediterranean, ongoing hostilities in Ukraine Spring, the fall of the Gaddafi regime in Libya and and the reemergence of Cold War rhetoric, it might the humanitarian crisis in Syria, for instance – when be time to reverse this situation – and stand firm and the European Union’s lack of response was a disap- united. This implies not only conceding to concert- pointment to many. ed action, but also providing the necessary means Even the Treaty of Lisbon (2009) did nothing to to carry out joint activities. In this context, EU change the fact that member states are strongly fa- member states might have to rethink Europe’s secu- vored – and not the European Union. Most issues rity and defence apparatus and increasingly engage with foreign affairs, security and defense implications in pooling, sharing or better coordinating equip- are still handled by national governments, and not ment and resources. by the High Representative of the Union for Foreign This leads to yet another challenge, namely the Affairs and Security Policy, a position currently held question of whether and under what conditions the by Federica Mogherini. However, a Union with a low Union should resort to military means to maintain international profile, together with members states or restore peace (provided there is a UN mandate). divided over security and defense issues, is not the For most people, military activity is associated with most desirable message to convey to the world. member states deploying troops (mainly in the con- The path to more security and defense cohesion text of NATO operations), not the EU. The Union’s in the future is thus not without obstacles. The first international standing and self-image has, to a large difficulty to be tackled relates to defining a common extent, been coined by its non-belligerent nature. European stance. Especially in crisis situations, na- Consequently, the EU has adopted a security strate- tional players are likely to fall back on national insti- gy that combines all elements of foreign policy (di- tutions and mechanisms. In addition, as questions of plomacy, trade, aid and military and non-military in- security and defense traditionally belong to the realm struments) and clearly prefers conflict prevention of the executive, governments are generally wary of over armed intervention. In fact, civilian missions ac- renouncing their prerogatives and responsibilities in count for almost two-thirds of EU-led crisis manage- Photo: dpa Picture-Alliance favor of common decision-making or implementa- ment activities. tion structures. For some member states, including Scandinavian The UK’s strong opposition to a change in the countries and Germany, the use of military force is status quo and to further integration in foreign af- not readily compatible with the Union’s civilian char- fairs, security and defense on the road to the Trea- acter. For other member states, like France, military ty of Lisbon is a case in point. Another example is interventions are considered to be an essential aspect 2 | 15 MaxPlanckResearch 13
of a Union that wants to affirm its international role. mer Federal President Horst Köhler insinuated in an So to what end(s) should military force be employed? interview that military intervention could, under cer- Should the Union intervene militarily to prevent tain circumstances, be required to safeguard the coun- atrocities from being committed? So far, member try’s interests, including free trade routes and the pre- states have, for pragmatic reasons, opted to carry out vention of regional instabilities. At the time he made humanitarian interventions, as in Libya, under the his statement, German navy forces had already been NATO framework, if at all, and not under the auspic- patrolling the Gulf of Aden for two years – appar- es of the Union. ently unnoticed by the German public. Also, what about sending armed forces, not to The episode reveals another stumbling block for maintain, but to restore peace? In several EU opera- European security and defense: the fact that member tions, the use of force has been authorized to curb in- states can avoid blame under the cloak of the Union. ternal conflicts and prevent regional instabilities – By engaging in EU military operations relatively un- such as in the Central African Republic in 2014. And yet, it is no simple task to gather military personnel and resources for these undertakings. Par- is is often willing to send soldiers and contribute A general tendency to blame materials. Berlin, on the other hand, is known to be Brussels a more reluctant contributor to military operations, and has a clear preference for civilian missions. As for the EU operation in the Central African Repub- known to the wider public, member states reduce the lic, France accounted for the majority of troops, risk of nasty questions or bad press at home. And if while Germany committed military transport air- anything goes wrong in an operation, national capi- craft to carry the wounded. The same division of la- tals can blame the Union for the failure. Although bor for combat tasks and logistical support – “exem- this might sound cynical, it’s not a far-fetched sce- plary,” as some might say – has also been applied in nario, bearing in mind the general tendency of na- other operations. tional players to blame Brussels for all sorts of unde- In different circumstances, member states have sired policy outcomes. The Union should therefore shown greater resolve to contribute armed forces. make its external activities more accessible to the This has been the case with, for instance, Atalanta, general public. the EU-led naval anti-piracy operation off the Soma- Ultimately, there is the challenge for the Union li coast. More than 20 member states (including Lux- to live up to its own expectations, which in turn emburg, a landlocked country with no naval forces) feeds into legitimacy questions. In the absence of and some non-EU countries are contributing to the proper scrutiny by the European Parliament in mat- operation. Apart from providing protection to vessels ters related to foreign affairs, security and defense of the World Food Programme delivering food to So- policy, and given the lack of jurisdiction of the Eu- malia, the operation is mandated to deter, prevent ropean Court of Justice over these same matters, the and repress acts of piracy and armed robbery at sea Union seems to fall short of the values it seeks to with a view to ensuring that international trade is not promote abroad, namely democracy and the rule of disrupted, and to use force if necessary. law. But applying double standards entails a consid- The Gulf of Aden is indeed one of the most im- erable reputational risk. portant international commercial maritime routes, This also holds true for transparency issues. For- not least because tankers loaded with crude oil are eign affairs, as well as security and defense matters, Photo: dpa Picture-Alliance transiting through the Gulf to reach nations all over are traditionally decided upon and conducted be- the world. Geo-strategic considerations and econom- hind a veil of secrecy. While restricted disclosure of ic interests clearly played a role in member states’ de- documents and access to information makes sense cision to take part in the operation. when it comes to military operations, it’s hard to Against this backdrop, it is astonishing that, in understand why there is little information dissemi- 2010, the German public was outraged when the for- nated on the outcomes of military missions or, even 14 MaxPlanckResearch 2 | 15
VIEWPOINT_Foreign Affairs more so, on civilian missions that deal, for instance, with the rule of law or policing. Furthermore, it would be important to establish accountability mechanisms with respect to matters of foreign, security and defense policy. The institu- tional and procedural setup of the Common Securi- ty and Defence Policy, subject to little parliamentary scrutiny and lacking judicial review at the European level, seems conducive to circumventing accountabil- ity. The corruption scandal that hit the Union’s flag- ship last November, the rule of law mission EULEX Kosovo, is one pertinent example. It was leaked to the press that high-ranking EU of- ficials had allegedly been involved in corruption. Even more problematic was the fact that representa- tives of the mission and Brussels-based structures seem to have attempted to cover up the story instead THE AUTHOR of properly investigating the allegations brought Carolyn Moser is a member of academic staff at the forth by a seconded prosecutor. These entanglements Max Planck Institute for Comparative Public Law prompted the High Representative Federica Mogheri- and International Law. She studied law, politics and ni, on one of her first days in office, to appoint an ex- economics at Sciences Po Paris and the Fletcher ternal expert to review and report on the incident. School of Law and Diplomacy (Tufts University) in Still, the Union and the mission have already suffered Boston. She spent the period between 2011 and 2013 reputational damage. The scandal has indeed caused at the Basel Institute on Governance, where she much bad press for the good EU cop. worked on projects to promote the rule of law and So, how to proceed? Jean-Claude Juncker, Presi- fight corruption in Asia, Europe and North Africa for dent of the European Commission, recently made a various organizations, including the World Bank controversial suggestion as to how to react to exter- and the OSCE. Since 2013 she has been working on nal threats and to restore the Union’s international her Ph.D. at the Max Planck Institute for Compara- standing: he resuscitated the ambitious project of a tive Public Law and International Law with research European army (in parallel with NATO structures). residencies in Utrecht. Juncker’s proposal was met with mixed reac- tions: foreseeably enough, the UK government re- jected the plan in no uncertain terms, stating that defense was undeniably a matter of national re- sponsibility, whereas the German minister of de- fense, Ursula von der Leyen, welcomed the prospect of a common army. The interlude shows that, even more than six de- cades after the failure of the European Defence Com- munity project, the time is still not ripe for a Europe- Photo: Maurice Weiss/Ostkreuz an army, even though member states have no choice but to rethink Europe’s security and defense mecha- nisms in the long term. But it also shows that there is a political will among some member states to strive for greater unity in foreign policy, security and de- fense – a unity that is needed to keep the European promise of peace. 2 | 15 MaxPlanckResearch 15
Post from London, England Immediate Inspiration Max Planck scientists cooperate with partners in around 120 countries worldwide. Here they relate their personal experiences and impressions. Empathy researcher Esther Kühn commutes back and forth between the Leipzig-based Max Planck Institute for Human Cognitive and Brain Sciences and University College London. She finds this cooperation to be extremely fruitful. Anyone who occasionally lands at a bustling airport like London’s Heathrow knows how much the modern world connects us to people – or at least it seems that way. Business trav- elers rush to meetings – they stumble, jostle each other and apologize. Grandparents who have traveled from far away carry grandchildren in their arms. Lovers wait for a special some- one who will soon walk through this sliding door, and who, perhaps, was away for too long. But how do people actually form these connections with each other? Which regions of our brain are active in this process, and how? This question has a long tradition in empathy re- search, and it has been my companion for some time. To be precise, I’m particularly inter- ested in a tiny sub-aspect: What happens in the brain when a person is touched? And what happens when that person merely observes another person being touched? To answer these questions, I went in search of suitable connections with other researchers. The right device, a magnetic resonance scanner, is already available at the Max Planck In- stitute in Leipzig, as are the right subjects. While they lay in the MRI tube, I stroked their fingers with a paintbrush – or they watched films of the same movement being carried out on another person. But this experiment generated huge quantities of data, and accurately Graphic: iStockphoto interpreting this data is a great challenge. Fortunately, during an initial term as a visiting researcher in England, I met my colleague Patrick Haggart from University College London. Then when I was in Leipzig and occasion- ally got stuck, we discussed it over Skype, sometimes even outside of working hours. And 16 MaxPlanckResearch 2 | 15
RUBRIK TITEL Esther Kü hn, 31, studied biolog y in Münster before co mpleting her ma ster’s degree in neuros cience in Otago, New Zealand between 2007 and 2009. Ba ck in Germany, she co nducted research as a doctoral student at the Max Planc k Institute for Human Cogn itive and Brain Sc iences in Leipzig until 20 13. With the aid of a grant from the German Academic Exchan ge Service (DAAD), sh e spent half a year at University Colle ge London (UCL). She returned to Leipz ig and, since 2014, has been a member of Arno Villringer’s Departm ent of Neurology. There , she is a major co ntributor to a strong coopera tion with UCL. together we considered how best to handle my data. At some point, he said: “Wouldn’t you be able to answer your questions better if you used my colleague Martin Sereno’s program here in London?” Of course! And since then, I spend a couple of months each year in the British capital. Now one might think that, in London, I need little more than a computer and a full coffee cup, but that’s not quite right. I sit in my office together with Martin, who is known as Marty, and I draw a lot of inspiration from speaking directly with him. It’s a great advantage! After all, he’s a renowned neuroscientist, and the program we work with is his “baby.” I have since even come up with new ideas that have nothing at all to do with my original proj- ect. That’s a tremendous advantage for a junior scientist. It’s also a huge boon for me that my colleague has just as much energy and enthusiasm for my project and spends so much time on it before speeding home on his racing bike in the evening through the rather bicycle-un- friendly streets of central London. For me, it’s then time to go to Pilates, or to my sword-com- bat class. After all, who wants to spend all day in front of the computer monitor? I’ve now spent a total of just over a year in London. And even though, as a native of Leipzig, I consider myself to be spoiled in terms of cultural offerings, London is an incredible step up. The city offers me every opportunity, and sometimes I’m almost overwhelmed by the cultural choices available. Just recently, I again attended a number of concerts and a classi- cal ballet performance. Nevertheless, it really did take me quite a while to find my place here. London is a logistical challenge, and it’s changing so fast. As an example, even today, Photo: Private collection I can’t estimate how long I’ll need for any given route – I’m simply always late. When I arrive back at Leipzig/Halle Airport after my adventures in London, everything feels much smaller. I’d say, compared with London, Leipzig is my living room. My home. But I’ve changed, and I’m full of new ideas. And even if my future research location hasn’t yet been entirely decided, I’m sure of one thing: my future in science has begun. 2 | 15 MaxPlanckResearch 17
FOCUS_Light Tweezers Made of Light Many biomolecules move through cells like microscopic machines. Often, however, it isn’t known what forces these molecules generate or how fast the molecules act or move. That’s why Stephan Grill from the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden decided to specialize in measuring molecular forces. He uses optical tweezers to pull gently on DNA strands. His method is shedding light on the proteins that read genetic information. TEXT TIM SCHRÖDER S prings are ubiquitous in the determines the spring constant. The croscopic machines powered by tiny modern world, whether in pens spring constant is measured by deter- forces. This is tremendously fascinat- or on the grips of garden clip- mining how much force is needed to ing.” Our muscles contract, for exam- pers. A spring is compressed or stretch or compress a spring through a ple, because millions of elongated pro- stretched, depending on its given distance. The force required de- teins slide along each other over min- function. This requires force, as the pends on the thickness and material of iscule distances. By combining all these spring resists any attempt to change its the spring. For example, stiff shock ab- tiny shifts, muscles are able to carry out shape. Springs can be very strong: the sorbers for sports cars shorten by just large movements. leaf springs of trucks, for example, eas- one millimeter in response to a force of The movements that interest Grill, ily support 20 to 30 tons. 70 newtons acting on them – corre- however, are smaller than those asso- To express the strength of a spring, sponding to the force generated as a car ciated with muscle proteins. He wants physicists perform a measurement that drives over cobblestones. to understand how RNA polymerase travels along DNA molecules while TINY POWER PACKS reading the genetic information the DNA encodes – a process known as Stephan Grill has nothing to do with transcription. shock absorbers, sports cars or leaf After decades of intensive research, springs. He deals with forces on a com- biologists, biophysicists and geneticists pletely different scale. The physicist now understand which molecules are from the Max Planck Institute of Mo- involved in transcription, what interme- lecular Cell Biology and Genetics mea- diate products are formed, and where sures forces that are a billion times the energy for the finely tuned genetic weaker than these. machinery comes from – but not the Grill isn’t interested in newtons and forces that are involved. “If we really kilonewtons, the units of force in every- want to understand the transcription Photos: Sven Doering day life, but in piconewtons, less than engine, we need to find out what drives a billionth of a newton, to express the it,” says Grill. “It’s like any other ma- forces acting between biomolecules. chine. If you don’t know how much “Biomolecules aren’t rigid and static,” force it generates, you don’t really un- says Grill. “Some proteins resemble mi- derstand how it works.” > 18 MaxPlanckResearch 2 | 15
Left: A foam box protects the optical tweezers from environmental factors such as temperature fluctuations and noise vibrations. A hoist can be used to lift the entire box or to open the lid. Right: Stephan Grill can load the sample to be investigated, or make changes to the setup through the open lid. The researcher wears special goggles to protect his eyes against the laser light.
Measuring forces – at the molecular ments, there can be no movements,” used a trick based on a finely focused level, this is no easy feat. For this, Grill says Ehrlich. “After all, we’re dealing laser beam. Like billiard balls, the pho- constructed a sophisticated experimen- with a high level of precision to within tons impinge on the bead from all di- tal setup when he was leader of a joint a millionth of a millimeter.” rections and hold it in place. It’s possi- group at the Max Planck Institute of What occupies a large box and a whole ble to capture and balance a ping pong Molecular Cell Biology and Genetics laboratory room is known by experts bead on the stream of air from a hair and the Max Planck Institute for the simply as optical tweezers. The sole pur- dryer. Ashkin achieved essentially the Physics of Complex Systems before pose of the entire apparatus is to cap- same thing with molecules and light. 2013. Together with his colleagues, he ture a protein, pull on it as if it were a Many research groups have since re- combines mirrors, lenses and high-pre- spring, and measure its resistance. It’s fined this prototype of optical tweezers. cision lasers to form an optoelectronic difficult to imagine how laser light can In recent years, researchers have used maze. And his tool for measuring bio- capture molecules, but the method, de- optical tweezers to study various bio- molecular forces is light. veloped by US physicist Arthur Ashkin molecules, including myosin and kine- Grill, who is now also a professor at in the 1980s, is well established. sin. Myosin, a motor protein that is the TU Dresden, is in the process of present in all our muscle cells, moves moving and shuttles back and forth be- BILLIARDS WITH PHOTONS in 14-nanometer increments. As it does tween the Max Planck Institute and the so, it causes muscle fibers to contract. TU laboratories – four minutes by bike. The dual nature of light as a wave and Kinesin moves through the cell in The laboratory at the Max Planck Insti- a particle has been known for a centu- 8-nanometer steps as it transports cell tute is currently housed in a small room ry. Light particles, called photons, pos- components. “We’ve perfected our op- that is almost entirely filled by a large sess momentum that can be imparted tical tweezers to the extent that we can gray styrofoam box. Next to it are a to an object. This happens, for example, even measure the movements of RNA chair and a table on which three com- when a photon flies through a tiny polymerase, which are ten times small- puter monitors sit. Grill’s colleague transparent bead and is deflected from er,” says Grill. Christoph Ehrlich opens the lid of the its path by light refraction. The photon DNA is the blueprint according to styrofoam box. Inside is a perforated propels itself away, pushing against the which the cell produces proteins. For Photo: Sven Doering plate the size of a tabletop. Mounted on bead. If the light is strong enough, the polymerase to read the genetic infor- the plate are lenses, mirrors and thin bead can actually be nudged to the side. mation contained in genes, it must first tubes that end in fist-sized chunks of But Arthur Ashkin wanted to achieve open up the DNA molecule, which con- stainless steel. “When the system is the opposite effect, namely to capture sists of two intertwined strands, like a running and we’re taking measure- the beads with laser light. To do so, he zipper. It travels, like the slide of a zip- 20 MaxPlanckResearch 2 | 15
FOCUS_Light Left: While Veronika Fitz and Stephan Grill look at data on the screen, Marcus Jahnel (left) prepares the optical tweezers for a new experiment. Right: RNA polymerase II reading a gene. The enzyme (blue) moves along the coiled DNA strands (yellow, pink), untwists them and transcribes the genetic information into an RNA molecule (orange). If the polymerase makes an error, the faulty RNA section is snipped off. The molecule then reverses and reads the gene segment again. The RNA molecule eventually serves as a template for protein synthesis. per, from one DNA building block to the two beads closer together until the detectors sense this deviation. A com- the next, always in 0.34-nanometer DNA from the first bead binds to the puter program then converts the devi- steps. These building blocks, called di- second bead, thus forming a tether be- ation of the beads away from the cen- nucleotides, represent the letters of the tween the two beads. The pair of beads ter of the traps into the force that the genetic alphabet. connected by the long DNA strand re- polymerase generates. As it reads the DNA molecule, poly- sembles a tiny dumbbell. What’s more, the researchers are merase strings together the RNA coun- At first, nothing happens, because also able to move the two beads back terparts of the dinucleotides, thus cre- the polymerase requires energy to trav- and forth, pulling on the DNA like a ating an RNA copy of the DNA strand. el along the DNA. Only when the re- miniscule spring. The spring constant “We want to know the strength of the searchers add energy-rich RNA nucle- of DNA is infinitesimally small: stretch- forces involved as polymerase moves otides as fuel do things get moving. ing a DNA molecule by one micron re- along the strand of DNA, and how The polymerase moves in increments quires a spring force of just one tenth quickly the enzyme progresses,” says from one nucleotide to the next. But of a piconewton. And because the Grill. “This is extremely difficult in because the two beads are held firmly polymerase is bound to and moves view of the short increments involved.” in the traps, a tensile force is created be- along the DNA, it has to act against The trick Grill and his colleagues tween the beads, like a rope on which these forces. use to measure the forces is impressive. two opponents are pulling in a tug-of- Because the RNA-polymerase complex war match. BEADS IN THE TRAP can’t be captured easily in an optical The polymerase must therefore ex- trap, Grill uses a kind of support struc- ert a force to move from nucleotide to Although the laser technique is extreme- ture: two small plastic beads measuring nucleotide. After each step, it remains ly complex, and the mirror laser beams just a few micrometers across. He at- stationary for a few seconds, during must be precisely adjusted, the trap is taches a polymerase molecule to one of which the force on the other bead re- amazingly simple to operate. Grill’s doc- the plastic beads, and a DNA strand to mains constant. When the polymerase toral student Veronika Fitz holds a joy- the other. This is where the optical takes the next step, it has to apply even stick while gazing at a computer screen. Photo: SPL-Agentur Focus tweezers – or more precisely, two opti- more force against the growing resis- Somewhere in the depths of the styro- cal tweezers – come into play. Grill and tance. While the polymerase progress- foam box, the beads move through a his colleagues use one to hold the bead es and the tension on the DNA increas- small container, and their magnified im- with the attached polymerase-DNA es, the beads are gradually pulled out of ages appear as tiny dots on the screen. construct, and the other to hold the the focus of the laser beams by just a The light beams of the two traps appear second bead. They then carefully move few nanometers. High-resolution light on the screen as crosshairs. > 2 | 15 MaxPlanckResearch 21
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