Kontrollieren Sie die Ausbreitung von VRE bevor es Sie kontrolliert - Thermo Fisher Scientific

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Kontrollieren Sie die Ausbreitung von VRE bevor es Sie kontrolliert - Thermo Fisher Scientific
Kontrollieren Sie die Ausbreitung von
VRE bevor es Sie kontrolliert
Kontrollieren Sie die Ausbreitung von VRE bevor es Sie kontrolliert - Thermo Fisher Scientific
Brilliance VRE                               ™

Detektion von Vancomycinresistente-Enterokokken (VRE)

Brilliance™ VRE Agar ist eine chromogene Screeningplatte
zum Nachweis von Vancomycinresistente-Enterokokken
(VRE). Das Medium bietet eine präsumtive Identifizierung
von Enterococcus faecium und Enterococcus faecalis,
direkt aus klinischen Proben.

Zeitsparend
• Präsumtive Identifizierung von Vancomycinresistenten
  E. faecium und E. faecalis nach 24 Stunden, direkt aus
  der Probe

Bequem und Einfach Anzuwenden                                                                Die Unterscheidung zwischen Vancomycinresistenten
• Schnelles und einfaches Screeningtestverfahren                                             E. faecium und E. faecalis wird erzielt durch zwei
                                                                                             chromogene Substanzen, welche durch spezifische
• Klare Unterscheidung zwischen E. faecium und                                               Enzyme gespalten werden: Phosphatase und
  E. faecalis                                                                                α-Galactosidase. Die Spaltung der Chromogene
• Direkte Beimpfung aus Stuhlproben, Probentupfern,                                          durch diese Enzyme resultiert in einer Farbgebung
  Isolaten oder Suspensionen                                                                 der Kolonie. Die Entstehung der Farbgebung ist
                                                                                             abhängig von dem Enzym, welches der Organismus
Selektiv                                                                                     besitzt. Sowohl E. faecium als auch E. faecalis
• Die Inhibierung der natürlich resistenten E. casseliflavus                                 exprimieren die Phosphatase, welche eine
  und E. gallinarum reduziert falsch-positive Ergebnisse im                                  Blaufärbung der Kolonien hervorruft. Da E. faecalis
  Vergleich zu traditionellen Medien und minimiert dadurch                                   zudem noch die α-Galactosidase besitzt, entsteht
  den Einsatz von Bestätigungstesten                                                         durch eine Mischung der beiden Chromogenen
                                                                                             die violette Färbung der Kolonien, was eine
Kostensparend                                                                                Unterscheidung zu den blauen Kolonien von
• Infektionskontrollmaßnahmen und eine adäquate                                              E. faecalis erleichtert.
  Behandlungstherapie können durch die frühzeitige
  präsumtive Identifizierung von E. faecium und E. faecalis                                  Die Zugabe von weiteren antibakteriellen
  zeitnah eingeleitet werden.                                                                Komponenten, in Kombination mit Vancomycin,
                                                                                             unterdrücken das Wachstum der Begleitflora wie
                                                                                             E. casseliflavus und E.gallinarum, welche eine
                                                                                             natürliche Resistenz, die chromosomal vermittelte
                                                                                             VanC Resistenz, gegen Vancomycin besitzen.
References:
1. Bell J.M., Paton J.C., Turnidge J. (1998). Emergence of Vancomycin Resistant              Die VanC Resistenz ist nicht übertragbar auf
   Enterococci in Australia: Phenotypic and Genotypic Characteristic of Isolates. J. Clin.
   Microbiol. 36, 2187-2190.                                                                 andere Organismen und ist klinisch signifikant
2. Centers for Disease Control and Prevention (2006). Recommendations for Preventing         unbedeutender, als die VanA und VanB Resistenz.
   the Spread of Vancomycin Resistance: HICPAC.                                              Die VanA und VanB Resistenz wird über genetische
3. Delmas J., Robin F., Schweitzer C., Lesens O., Bonnet R. (2007). Evaluation of a new
                                                                                             Elemente wie Plasmide und Transposons übertragen
   chromogenic medium, chromID VRE, for detection of Vancomycin Resistant Enterococci
   in stool samples and rectal swabs. J. Clin. Microbiol. 45, 2731-2733.                     und erhöhen somit das Risiko der Übertragung der
4. Data on file at Oxoid, based on growth or inhibition.                                     Resistenzgene auf andere Organismen.

2
Kontrollieren Sie die Ausbreitung von VRE bevor es Sie kontrolliert - Thermo Fisher Scientific
Performance                                                                                                                             Oxoid Brilliance Agar Ready-Poured Plates
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                                                                                                                                                                                                                      5x50   discs                 CT0058B
                                                                                                                                              Vancomycin         256 - 0.016μg/mL                             10 strips                   MA0102D
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Brilliance Fertignährmedien
Bestellinformationen
    Produktname                                                                                                             Packungsgröße                                   Art.-Nr.
    Brilliance VRE Agar                                                                                                     10x90 mm Platten                                PO1175A
    Weitere Produkte der Brilliance Screeningmedien Produktpalette
    Brilliance MRSA 2 Agar (UK)                                                                                             10x90 mm Platten                                PO1210A
    Brilliance MRSA 2 Agar (Europa)                                                                                         10x90 mm Platten                                PO5310A
    Brilliance ESBL Agar                                                                                                    10x90 mm Platten                                PO5302A
    Brilliance CRE Agar                                                                                                     10x90 mm Platten                                PO1226A
Das Thermo Scientific Produktangebot bietet die komplette VRE Screening und Testungslösung:
    Culti-Loops™
    Postive-Qualitätskontrollstämme:
    Enterococcus faecalis (Vancomycin Resistant) ATCC® 51299™†                                                                                                              R4601996
    Negative-Qualitätskontrollstämme:
    Enterococcus faecium ATCC® 35667™†                                                                                                                                      R4601956
    Enterococcus faecalis ATCC 19433                ®             ™†
                                                                                                                                                                            R4601990
    Enterococcus gallinarum ATCC 700425                  ®              ™†
                                                                                                                                                                            R4601958
    Enterococcus casseliflavus ATCC 25788                     ®          ™†
                                                                                                                                                                            R4609289
    Enterococcus faecalis ATCC® 29212™†                                                                                                                                     R4607030
    Escherichia coli ATCC 25922          ®              ™†
                                                                                                                                                                            R4607050
    Bestätigungstests
    Thermo Scientific™ RapID™ STR                                                                                           20 Tests                                        R8311003
    Zur schnellen Identifizierung von Entero- und Streptokokken

    Streptococcus Grouping Kit                                                                                              50 Tests                                        DR0585A
    O.B.I.S. PYR                                                                                                            60 Tests                                        ID0580M
    Antibiotika-Testblättchen
    Testblättchen zur antimikrobiellen Empfindlichkeitsprüfung mit geeignetem Nährmedien nach CLSI M44-A.

    Vancomycin 5 μg Discs                                                                                                   5x50 Testblättchen                              CT0188B
    Vancomycin 30 μg Discs                                                                                                  5x50 Testblättchen                              CT0058B

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