INTERN MANUAL SURVIVAL GUIDE - LOYOLA INTERNAL MEDICINE 2020 - 2021 Academic Year - Loyola Medicine

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INTERN MANUAL SURVIVAL GUIDE - LOYOLA INTERNAL MEDICINE 2020 - 2021 Academic Year - Loyola Medicine
LOYOLA INTERNAL MEDICINE

INTERN MANUAL
      &
SURVIVAL GUIDE

      2020 - 2021 Academic Year
              11th Edition

    A handbook of tips, tricks and
   approaches to the most common
  intern calls, pages and diagnostic
              challenges
INTERN MANUAL SURVIVAL GUIDE - LOYOLA INTERNAL MEDICINE 2020 - 2021 Academic Year - Loyola Medicine
Name/Pager #:               ____________________                                      NOTES
Locker #:                   ____________________
How to Page or Call to and from Loyola to Hines?
 To page a Loyola pager from Loyola or Hines: dial 9-643– then 4 digit
     pager number, after prompt enter call back number, then #
   To page a Hines pager from Hines or Loyola: Dial 9 then the pager num-
     ber, after prompt enter call back number, then # (Hint: Hines pagers start
     with 988)
   To call from Loyola to Hines: dial 9-202-VETS (8387) then the 5-digit ex-
     tension, then # (Hint: Hines ext. almost always start with 2)
   To call from Hines to Loyola: dial 9-216 then last 4 numbers
   To call Loyola from outside - dial 708-216 then last 4 numbers
   To call Hines from outside: dial 9-202-VETS (8387) then the 5-digit exten-
     sion, then #
   If ever having trouble reaching an attending to staff a patient, call the Loy-
     ola answering service at 66400.
   You can also always use your Cureatr app for paging and texting as well,
     but do not rely on this for urgent needs. It is always best to actually talk
     with someone over the phone if it is an urgent matter!

How to Consult? This will get you to the name and pager # of the person
on various consult services.
 At Loyola: in EPIC, go to “Web” > “Web On Call” > “Quick AM” or “Quick
    PM” if after 5 PM
 At Hines: in CPRS, go to Tools — Clinician Tools — Clinical Resources
    (left hand column) —VISN 12 On Call Schedule —Hines-Day On Call
    Schedule or Evening if after 5 PM
 At Hines, there is also a link to “VISN 12 On Call Schedule” on the Inter-
    net Explorer homepage found on the desktop
 Please talk with your senior resident before placing a consult

How to know who’s on call & your call schedule?
1.   Go to www.Amion.com
2.   Password: “loyolaim”
   Here you will find who is on call each day, including your personal sched-
     ules, clinics, and call days for the year

How to find someone’s pager or number in the hospital
• Refer to the Green card for Loyola or the Yellow Card for Hines.
 Search Loyola faculty: in EPIC, go to “Web” > under phone directory click
     “search” (near the middle left of page) > you can then search by first and
     last name or reverse search a pager number
   Search Hines faculty: open the Internet Explorer homepage > click on
     “Phonebook” (near middle of page) > you can search by first and last
     name

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INTERN MANUAL SURVIVAL GUIDE - LOYOLA INTERNAL MEDICINE 2020 - 2021 Academic Year - Loyola Medicine
NOTES                  TABLE OF CONTENTS

             A Day in the Life of an Intern……………….… .....                       4
             Sign-Out ………………………...………….….. .....                                5
             Discharge Summaries…………………………. ....                                6
             Expiring Meds & Restraints / Incident Reporting…                   7
             Hines Gen Med Discharge Process…………. .....                         8-9
             Useful Equations…………..…..…...................... ..                10
             Sepsis…………………………...……...…… ..........                              10-13
             Hospital Prophylaxis…………………………….....                               14
             Transfusions / Consent / Death exam……..….....                      15
             Electrolyte Disturbance……………………..……. .                             16-20
             Heme/Onc Emergencies…….……….……....…. ..                             20
             Acid-Base Disturbance….. …..………………...….                            21-22
             Insulin, Glycemic control & DKA………...….........                    23-24
             Sleep Issues………………………….…………….                                      25
             Altered Mental Status……………………..............                        25
             Pain Control………………………...… ..................                       26
             Falls…………………………………….. .................                            27
             Fever……………...… ...........................................         27
             Neurology…………………………….…………… ..                                      28
             Alcohol Withdrawal………… ................................            29
             Anemia………...…… ............................................        29
             Chest pain / Acute Coronary Syndrome.…… ......                     30
             Blood Pressure…………………...….....................                     31
             EKG Interpretation……………………………….. ..                                32-33
             Post-Cath Groin Check…………..........................                34
             Atrial Fibrillation……………………………............                         34
             CHADSVASC, HAS-BLED & “bridging”…………                               35
             Pre-op Cardiac Risk Stratification………….… .....                     36
             Dyspnea / Hemoptysis………...….… ...................                  37
             LVADs……… .......................................................   38-39
             Mechanical Ventilator / PFTs…………………… ..                            40-41
             GI bleed, Abdominal Pain & GI Symptoms…. .....                     42
             Low Urine Output / Urology Issues…………….. ..                        43
             ENT Pearls……..……………………...……. .........                             44
             Helpful Contacts and Numbers…………….. ........                       45
             ACLS Algorithms…….…………………….. ..........                            46-49
             COVID-19……..………………….…………………                                        50-51
             How to Log Admissions …………………………..                                 52
             How to Log Procedures……………………………                                   53
             Personal Notes…………………………………. ....                                  54-59

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INTERN MANUAL SURVIVAL GUIDE - LOYOLA INTERNAL MEDICINE 2020 - 2021 Academic Year - Loyola Medicine
A DAY IN THE LIFE OF AN INTERN
                                                                               NOTES
    There are many tasks and responsibilities on any given day so it’s
    important to find a system to stay organized and efficient.

    If you follow these steps to structure your day you’re bound to be a
    successful, effective, and efficient intern.

    When you first arrive in the morning...

    1.  Un-forward personal pager and collect team pager (if any)
    2.  Get sign-out from cross-coverage
    3.  Check if any new admissions
    4.  Assess and respond to urgent issues if any
    5.  Print out new list > start making check boxes (“To do list’) for the
        day
    6. Make sure no meds/orders are falling off, renew if appropriate
    7. Review chart information over the last 24hrs (should record
       details and bring with you for rounds):
          a. Nursing notes
          b. Consult team notes
          c. SW / other ancillary staff notes
          d. Review vitals, I/Os, weights
          e. Review medication administration if pertinent
          f. Glycemic control (accuchecks, how much CF insulin given)
          g. Labs– replete electroytes & adjust insulin right away
          h. Imaging, other studies
    8. Pre-round (see ALL of your patients)
    9. Attending teaching rounds
    10. Round with SW, case manager/PCC at scheduled times (see
        your rotation specific instructions for times and location)
    11. Place urgent orders and consults
    12. Get to noon conference ON TIME! Bring your lunch!
    13. Work on discharges
    14. Place less urgent orders and calls
    15. Get the rest of the work done: other orders, procedures, family
        calls/updates, patient re-evaluation/care issues
    16. Write progress notes
    17. Complete discharge summaries
    18. Incorporate teaching/learning for your team (lead by attendings,
    senior residents, interns or med students!)
    20. Update sign out report
    21. Sign out (time specific to your rotation)
    22. Forward pager to cross coverage
    23. Read something specific to your patients that evening

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INTERN MANUAL SURVIVAL GUIDE - LOYOLA INTERNAL MEDICINE 2020 - 2021 Academic Year - Loyola Medicine
NOTES                                  SIGN-OUT

             How to edit and print Sign Out:
              LUMC/EPIC: Pt Lists tab > write handoff > edit information in pop-up box > close >Print
                Handoff
              HVA/CPRS: While signed into CPRS > Tools > Hand Off Tool > edit pop-up box > file
                > print

             Components of Sign-Out
             1) Age
             2) Sex
             3) Brief PMH significant to their presentation / hospitalization
             4) Pertinent presenting signs & symptoms
             5) Significant work up and findings (i.e. CT PE today +)
             6) Working Diagnosis and treatments (i.e. heparin gtt)
             7) Important events of the day
             8) On Call to do list: use [ ] boxes (if need to f/u with something, give advice what to
                 do with results. (i.e. [ ] 16:00 BMP, replete K prn) (NTD=nothing to do)
             9) Code Status MUST be listed, even if full code
             10) “Anticipated events” list things to watch for / what to do (i.e. high risk for respiratory
                 failure or high risk for volume overload)
             11) Contact info if pertinent (family member #)
             12) Identify and communicate the patients you are most concerned about

             Tips:
             - Make sure labs and meds are ordered as desired and not falling off
             - If there is a commonly requested treatment that you DON’T want your pt to get, list it in
             the “anticipated events” section (i.e. no opiates, no changing pain meds, no IV Benadryl,
             not allowed to leave AMA, etc)
             - If a lab or test result would never require overnight intervention, then don’t make it a
             checkbox!
             - Be sure to update daily, don’t let old events stay on your signout indefinitely!
             - Think about what you would want to know about a patient and their condition if you were
             the cross-cover resident!

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INTERN MANUAL SURVIVAL GUIDE - LOYOLA INTERNAL MEDICINE 2020 - 2021 Academic Year - Loyola Medicine
DISCHARGE SUMMARIES                                           NOTES

 HVA: see page 8
 Loyola : Note type is Discharge Summary, template is “IP dis-
   charge summary”
 MUST be completed within 24 hours of discharge!!

Include the following:
1. Date of admission and discharge
2. Primary Diagnosis: Main reason for hospitalization
3. Secondary Diagnoses: The rest of the medical problems ad-
dressed during the hospitalization. If you gave a med for it, include
it as a secondary diagnosis. Type these in yourself, do not rely on
computer to auto-populate them as they are frequently incorrect!
4. CONCISE summary of the presentation and hospital care:
Summary of the main points of the reason for admission with the
focus on the hospital course and what was the treatment. Refer
only to *key* labs/studies as appropriate. Always include medica-
tion changes and outstanding labs that need follow up. DO NOT
COPY AND PASTE!
5. Physical exam? You can count your discharge summary as the
day’s Progress Note if you include a physical exam in the dis-
charge summary. If you have written an additional progress note
for the day, there’s no need to document a physical exam.
6. Discharge medications: Make sure it is clear for both patient
and future reader of your discharge summary EXACTLY what the
patient is going home on. Make sure this is accurate—remember
that if you make a medication change after you’ve started your dis-
charge summary, you’ll need to refresh the template that autopopu-
lates the medication or the change will be missed.
7. Follow up: include appointments, labs, studies ordered / sched-
uled
8. Don’t forget to send a copy to the PCP (this is NOT done auto-
matically)
          CPRS/GUI: add PCP as additional co-signer to h/p and d/c
summary

Important discharge pearls to include in summary:
- Discharge weight in CHF patients
- Pending cultures that haven’t been finalized
- Follow up labs needed and when
- Be careful with abbreviations, always better to type it out if there
could be any potential confusion

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INTERN MANUAL SURVIVAL GUIDE - LOYOLA INTERNAL MEDICINE 2020 - 2021 Academic Year - Loyola Medicine
EXPIRING MEDS & LABS
     NOTES                        RESTRAINTS ORDERS
             -This should be checked every morning and evening prior to leaving for
             the day.
              Be mindful that certain antibiotics will fall off if initially approved for a
                short duration (they will need to be renewed)
              If ordering medications on admission, set duration for a long period to
                avoid them falling off the MAR
              To easily see expiring orders in EPIC, go to the “Manage Orders” tab >
                in the “sort by” dropdown menu select to “expiring”

             •       At Hines labs need to be entered daily. Review view alerts daily for
                     notifications of expiring orders
             •       Restraint orders are to be entered every 24 hrs (only if truly needed)

                            INCIDENT REPORTING

                 At Loyola:

                 •    Should you witness a significant harm event, you should report it
                      immediately to Risk Management/Patient Safety (listed in Web On
                      Call). They will be able to assist you in handling the event and af-
                      termath.

                 •    Otherwise, all incidents and near misses can be reported through
                      the VOICE system found on the portal under the link “Patient Safety
                      Reporting”.

                 At Hines:

                 •    All incidents and near misses can be reported through the EPER
                      system. The link for this can be found on the Hines VA desktops.
                      Additionally, you should notify your senior resident, attending and
                      fellow as well as the Hines Chief Resident.

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INTERN MANUAL SURVIVAL GUIDE - LOYOLA INTERNAL MEDICINE 2020 - 2021 Academic Year - Loyola Medicine
HINES GEN MED DISCHARGES
                                                                                            HOW TO LOG PROCEDURES
These instructions are for Hines Gen Med ONLY—we are not using                        Please log your procedures in New Innovations (https://new-
this process for other Hines rotations. If you need help with this, ask!!             innov.com/login). You will need to have an adequate num-
                                                                                      ber of procedures supervised by a senior resident, fellow or
1.    Go to Notes tab —> New Note—>enter note title GEN MED Prelimi-
      nary Discharge Document”                                                        attending and logged in New Innovations before you may do
2.    Set-up for your dual monitors: Drag the note over to the secondary              them independently. You will also have procedures logged
      screen and maximize it. **You must drag the note back to the primary            during simulation assessments (ABG, central line placement,
      screen before you sign the note!** On the primary screen, select the            ACLS mock codes, IO lines, peripheral IVs)—these will be en-
      Meds tab. Maximize the Outpatient Medications section and make sure             tered by Jill Wallock.
      you can visualize the status of each med (Active, Expired, Discontinued).
3.    Complete med rec by comparing inpatient meds within the note to the
      outpatient meds.                                                                1. On the dark blue menu bar, choose Logger
4.    Assign the medication status in the note—mark the status of each med            2. Choose Procedures
      listed (the status selection is not an order).                                  3. Enter the patient MRN (or first initial+last 4 of SS# for
5.    Update the outpatient medication orders in the Outpatient Medications              Hines patients) and DOB
      section as you go through the inpatient meds listed in the note.                4. Enter the date you performed the procedure
6.    Make any needed changes to non-VA meds and other outpatient medica-
      tions.                                                                          5. Use Location to indicate Loyola or Hines
7.    Go to the Orders tab and sign all the med changes but DON’T SIGN                6. Select the procedure from the drop down menu. If nec-
      THE NOTE YET!                                                                      essary, you may select other and then enter the type of
8.    Complete the remainder of the Preliminary Discharge Document and                   procedure in the comment box. CPT code is not required.
      click “Finish” once you’ve signed the med orders. (If the “Finish” button       7. Select a supervisor (your attending) from the drop down
      is locked, see Troubleshooting)
9.    In the next window, hit “Click Here” to place the Pharmacy Consult if it           menu. If your attending is not listed, you may choose Dr.
      is between 8 and 3 PM on non-holiday weekdays. If it is not during                 Simpson and type your attending’s name in the comment
      these times, click the alternative option which will skip the consult. If          box.
      you accidentally skip the consult, see Troubleshooting.
10.   Click “Accept” to accept the Anticipated Discharge Order.
11.   Go to File —> Refresh Patient Information. A window will pop up with                  Procedure                                 Number needed
      things for you to sign. Now you can sign all remaining orders and notes.              ACLS participant (indicate role)**             3
12.   Go the Notes tab and make sure you have signed the Preliminary Dis-                   Arterial line placement                        5
      charge Document Note.                                                                 Arthrocentesis (site in comments)              5
13.   If a Pharmacy consult is ordered, await the consult reply (up to 2 hours).            Central line placement                         5
14.   When the pharmacy calls you (or writes note), immediately revise any
      orders as needed.
                                                                                            Central line removal                           5
15.   Go to the Notes tab and enter note title GEN MED Patient Discharge                    Abscess I&D                                    3
      Instructions (TAKE-HOME) BETA. Revise/rewrite any medication                          IO line placement                              3
      instructions to the patient as needed.                                                Lumbar puncture                                3
16.   Enter and sign the discharge order. Do not delete the discharge order if a            Nasogastric intubation                         5
      nurse asks you to (refer to CR or inpatient leadership team as needed).
                                                                                            Pap smear/endocervical culture                 3
17.   Go the D/C Summary tab and complete GEN MED Discharge Sum-
      mary note within 24 hours of discharge if it is your progress note                    Paracentesis                                   5
      (contains physical exam) or within 48 hours of discharge if it is additional          Peripheral IV placement                        3
      to the day’s progress note. Note: you cannot start this until the GEN                 Peripheral blood draw                          3
      MED Preliminary Discharge Document is completed!                                      Thoracentesis                                  5

                                                                                     **You do not have to participate in 3 codes before running one—we are just
                                                                                     keeping track of numbers for this category

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INTERN MANUAL SURVIVAL GUIDE - LOYOLA INTERNAL MEDICINE 2020 - 2021 Academic Year - Loyola Medicine
HOW TO LOG ADMISSIONS
                                                                                             Troubleshooting/Tips:
                                                                  **If the Finish button on the GEN MED Preliminary Discharge Docu-
                                                                       ment is locked…
You are responsible for doing at least 50 admissions (initial     ...and all information has been completed in the note, go to the Notes tab and
H&P and admission orders) during your intern year. These                select the title of the GEN MED Preliminary Discharge Document on
should be logged in New Innovations (https://new-                       the left-sided notes column. Return to the open note and click the Finish
innov.com/login). Please update this regularly so that you              button.**
don’t lose track of the patient info and then have trouble log-   **If you accidentally skip the Pharmacy consult or if you completed the
ging it later. It makes sense to update this at the same               preliminary discharge document the previous night…
time you log your duty hours every 2 weeks.                       ...you can order the consult without repeating the entire process. Go to IN-
                                                                       PATIENT CONSULTS —> Medicine Consults —> see last item on the
1. On the dark blue menu bar, choose Logger                            list and click on “Preliminary Medication Reconciliation request.**
2. Choose Log Books                                               **If it has been over 1 hour and you haven’t heard from Pharmacy or if
                                                                       you have any questions for Pharmacy related to the discharge…
3. Click Add New Entry. The following screen will appear:
                                                                  ...please call or page the pharmacy. Ext 23187 or 23235; pager 988-8616.**
                                                                  **If you simply must work on your discharge summary before the rest of
                                                                       the process is done…
                                                                  ...Go to Notes—>enter note title STICKY NOTE and you can start working
                                                                       on the discharge summary, which can be copied and pasted into your
                                                                       actual discharge summary later.
                                                                                            Using the Dual Monitor
                                                                       Every dual monitor computer station has a primary and a secondary
                                                                       monitor. When you drag notes or CPRS onto the secondary monitor,
                                                                       please know that you may experience CPRS on a single monitor com-
                                                                       puter. This is because CPRS “thinks” that you are still using the dual
                                                                       monitor and therefore the note you are trying to write is not visible to
                                                                       you because it is being displayed on the non-existent second monitor.
                                                                       This is a problem with the software. To avoid it: Drag any notes or
                                                                       CPRS windows back to the primary monitor before signing notes or
                                                                       closing CPRS. If it happens to you: Call the Help Desk at 4HELP
                                                                       (44357) and ask them to help you with “Clear Size and Position Settings
                                                                       for User.”
                                                                  Contact us for questions/issues/feedback:
4. Enter the date of admission, MRN (or first initial+last 4      1st call: Meghan O’Halloran (Internal Medicine): pager 988-0913, cell 847-
   of SS# for Hines patients), Hospital, and Service                   736-7331
                                                                  2nd call: Adam Van Huis, Leo Gozdecki or Fizza Hussain (Chief Residents)
                                                                  3rd call: Rommel Pardo (Informatics): Ext 27244

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INTERN MANUAL SURVIVAL GUIDE - LOYOLA INTERNAL MEDICINE 2020 - 2021 Academic Year - Loyola Medicine
USEFUL EQUATIONS                                                                                                COVID-19
A-a Gradient: (mmHg)
 A-a = FiO2 (713) - (PaCO2/RQ) - PaO2
     FiO2 = 21% on RA, ↑ ~3-4% per L nasal cannula
         713 = [760 (Patmosphere) - 47 (Pwater vapor)]                                         Ancillary Services are available for COVID+ patients:
         ABG provides PaCO2 and PaO2                                                           • CT/MRI have protocols in place for scanning COVID+ patients
         Respiratory Quotient (RQ) = 0.8 (diet dependent)                                      •     Avoid reflex ordering PT/OT/speech to limit unnecessary exposure. But remember that if patients have
                                                                                                       been intubated/proned/paralyzed for a prolonged period of time PT/OT will be a critical to their overall
                                                                                                       recovery
    Estimated normal A-a = (Age/4) + 4
                                                                                                 IF patient would benefit from services, place order as usual but specify within order the following:
Fick Cardiac Output:                                                                             • “Discussed with attending on rounds. Okay to proceed with ancillary services”
Oxygen consumption (L/min)= CO (L/min) x arteriovenous (AV) oxygen difference                    •    “Nursing has initiated or attempted mobility”
          (must be measured, approx 125 ml/min/m2)                                               •    Prior to speech evaluation, have nurse assess at bedside
** Cardiac Output (L/min)= oxygen consumption/[Hb x 13.6 x (SaO2-SvO2)]                          •    Patients will likely be seen at the end of the day
                                                                                                 Protected Codes/RRTs:
Mean arterial pressure (MAP)= [SBP + (DBPx2)]/3                                                  • Fellow and senior should be present for all protected codes and rapid responses
Minute Ventilation (VE)= tidal volume (VT) x RR (nl 4-6 L/min)                                   •    Bring blue jump bag (located in 4853) that contains PPE
Corrected Calcium= Measured calcium + [(4-measured albumin x 0.8]                                •    Minimize number of people in room. Ideally (primary RN, RRT RN, RRT RT, primary physician, COVID
Corrected Na in Hyperglycemia= Measured Na+[2.4x[(measured glu-100)/100]]                             MICU fellow)
Anion Gap (AG)= Na-(Cl+ HCO3) (nl 12)                                                            •    Most senior physician should be code leader
Calculated Osmoles= (2xNa) + (glu/18) + (BUN/2.8)                                                •    Ask RT to place in-circuit spacer to allow for breathing treatments
Osmolar Gap (OG)= Measured osmoles—calculated osmoles (normal
SEPSIS
                                         COVID-19
                                                                                                                                       qSOFA                                         SIRS
                                                                                                                             Hypotension: SBP < 100 mmHg                     Temp: 38 C
    **Disclaimer: our understanding of how to manage and treat patients with COVID-19 is constantly evolv-
    ing, so please consider this information as a guideline and refer to the SharePoint documents and corona-                                                               RR >20 or pCO2 < 32
    virus central on the spirit homepage for more recently updated information. Please see the MICU Manual                       Tachypnea: RR ≥ 22
    for a more detailed guide.                                                                                                                                                     HR >90
Clinical Presentation:                                                                                                              AMS: GCS < 15
                                                                                                                                                                      WBC: >12k, 10% bands
•     Week 1 prodrome of mild symptoms, week 2 progressive dyspnea with eventual rapid respiratory decom-
      pensation
• Symptoms: cough, dyspnea, fever, GI, URI sx, loss of sense of smell and taste                                                           SOFA                             Sepsis-2 Organ Dysfunction
•    High Risk Features: age, CAD, HF, CKD, COPD, DM, immunocompromised/HIV                                          Resp      PaO2/FiO2 12                  4                       aPTT >60
•       Tocilizumab (IL-6 inhibitor) should be considered to prevent cytokine storm (this decision is made by ID     Heme      Platelets
SEPSIS INITIAL Rx ALGORITHM   ACLS: BRADYCARDIA

12                                                     49
ACLS: TACHYCARDIA     SEPSIS INITIAL Rx ALGORITHM

                            1   What to do at “Time Zero”?
                                 Type “sepsis” into order sets and choose IP SEPSIS OR-
                                    DER SET ADULTS ONLY. Use this to order antibiotics,
                                    blood cultures, and lactate and crystalloid if needed.
                                 Order empiric antibiotics, based on clinical judgement

                                What counts as hypotension?
                            2
                                  SBP < 90 or MAP < 65 or SBP drop of 40 from baseline

                                Which fluids are crystalloid?
                            3
                                 Saline (use 0.9%) and Lactated Ringer’s
                                How much should I give?
                                  30 cc/kg started within 3 hours of time zero and completed
                                    within 6 hours of time zero infused as boluses

                                What is the fluid reassessment note?
                            4
                                  In any progress note or H&P, type “.6”. 2 options will ap-
                                    pear: 6HRSEPSISCVP and 6HRSEPSISFOCUS. You
                                    may use either depending on which clinical information you
                                    have.
                                 6HRSEPSISCVP: Need at least 2 of the following: CVP,
                                    beside ultrasound of IVC, pulse pressure for passive leg
                                    raise
                                 6HRSEPSISFOCUS: Document physical exam for mucus
                                    membranes, cardiac, pulmonary, cap refill, pulses, and
                                    skin exam
                                   Remember that if this note is needed, it needs to be done
                                     within 6 hours of time zero!

                         Sepsis Workflow

48                                                                                               13
HOSPITAL PROPHYLAXIS                                                                        ACLS: ROSC / POST-CODE CARE
Primum non nocere- First do no harm
Every patient needs to have the following addressed and documented in notes:

• IS (incentive spirometer)
           -order on admission for everyone that isn’t intubated
           -decreases rates of atelectasis and HAP
           -ensure patient knows how to use it (show them)
           -should be used 10 x every waking hour

• GI prophylaxis for stress ulcers (SRMD-stress related mucosal disease)
           -ICU patients have ↑ gastric acid secretion and ↓ protective barriers
           -Current guidelines recommend NO routine prophy for Non-ICU med/surg
           patients
           -In short, give it to all ICU patients, but stop at discharge, don’t give a PPI
           to floor patients unless there’s a good reason.

       PPI Dosing                         Loyola                                  Hines

PO                            PO pantoprazole 40mg daily          PO omeprazole 20mg daily

PO via feeding tube           lansoprazole 30mg daily per tube    Lansoprazole 30mg daily per tube

IV (only use if strict NPO)   IV pantoprazole 40mg daily          IV pantoprazole 40mg or IV Famotidine

• VTE prophylaxis
  -order for every patient hospitalized for an acute medical illness
  -Pharmacologic prophylaxis is preferred over SCDs (as long as there is no contra-
  indication to anti-coagulation)

                          Dosing            Contraindications                Comments

SCDs                          -             • Evidence of leg       *Use if anticoagulation is
                                            ischemia from PVD       contraindicated
                                            • Evidence of DVT
Heparin sq        5000 units q8hrs          •   Hx of HIT           Short acting– TID dosing
                                                                    Risk of developing HIT=2.6%.
                                            •   ↑bleeding risk
                                                                                                          Hypothermia Protocol (at LUMC):
LMWH sq           Enoxaparin 40mg daily     •   Creatinine >1.5     Only once daily dosing                • Start within 1 hour of arrest (approved in ED, MICU, CCU, and 2ICU)
                                                                    Risk of developing HIT=0.2%.
                                            •   hx of HIT                                                 • Contact:
                                            •   ↑bleeding risk                                                    - Cards fellow (pg 12191)
                                                                                                                  - Neuro consult prior to paralysis (pg 91516)
                                                                                                          • Details:
                                                                                                            EPIC web tab → Clinical Protocols → LUMC Order sets/Guidelines → Ctrl+F
                                                                                                                 “hypothermia” for “Therapeutic Hypothermia” Practice Guideline

                                                                                                                                   TIME IS BRAIN!

14                                                                                                                                                                                    47
ACLS: PULSELESS ARREST    BLOOD TRANSFUSION / CONSENT
                              1)      Transfuse for Hgb
ELECTROLYTE DISTURBANCES                                                                             HELPFUL CONTACTS / NUMBERS
                                                                                                    PAGER PROBLEMS
     HYPERkalemia                                                                                   • Parking Office: x60297
     - First confirm it’s legitimate and sample is not hemolyzed. Repeat if so.
     - Etiology:
                                                                                                    EMR HELP
           ARF / CRF / Type IV RTA               Endocrinopathies (Addison’s,                     • CRPS: x22777 (can also contact LaWanda below)
           Meds (spironolactone, ACEIs,           hypoaldosteronism)                               • CPRS remote access: see LaWanda below
            ARBs, BBs, Digoxin, calcineurin       Cellular destruction (Tumor                      • VA desktop login: x44357
            inhibitors, etc.)                      Lysis Syndrome, rhabdo, burns,                   • EPIC: x63270 or x62160
           K+ in IV infusions / TPN               etc.)
                                                                                                    RESIDENT SUPPORT STAFF
     Emergency if: Rapid increase or EKG changes (peaked T’s, no P’s, wide QRS,                     • Jill Wallock (Loyola): x66053
     sine wave)
                                                                                                    • Stephen White (Loyola): x65522
     TREATMENT                                                                                      • LaWanda Urqhart (Hines): x24564
     Temporary (cellular shift): Used as bridge while waiting for effects of long-term                 GME office: x65620 or x64533
     1) IV Calcium– stabilizes cell membranes (lasts 30 min), essential if EKG changes
                                                                                                    • Human Resources / Benefits / Payroll: x63242 x63234 x62030
           Ca Gluconate 1-2 g (↓ risk of necrosis, but ↓ elemental Ca)
            Ca Chloride 1-2g (central line if possible to avoid necrosis)                         PATIENT AND EMPLOYEE SAFETY
     2) Insulin/Dextrose-10units regular insulin + 1 Amps D50 IV push (lasts 2-4 hrs)
     3) Bicarb (1-3 Amps IV push - only useful in acidosis)
                                                                                                    • Security (Loyola): 911 or x69077
     4) Albuterol neb (lasts 30-90 minutes)                                                         • Security (Hines): x22013 or x23200
                                                                         **Rebound hyperkalemia     • Risk management & Patient safety: x64215 or Pg. 708-643-0875
                                                                         likely if only temporary
     Long-term (Permanent Elimination): Start simultaneously with measures used**                   • Ethics service: 708-327-9219
          temporary measures
     1) Kayexalate- 30-90g PO/enema- (onset 1-2 hrs)
                                                                                                    • Needle Stick or bloodborne pathogen exposure: Page 708-643-0833
     2) Lasix IV- CAUTION as pts often dry, usually need high doses                                    immediately. Then go to Spirit homepage and in lower right corner under the
          (onset 30min)                                                                                “Quality and Safety” section click “Employee Safety” and follow instructions
     3) Hemodialysis —Follow up K+ q4-8hrs & treat underlying illness                                  for needle stick/bloodborne pathogen exposure
                                                                                                    • Too fatigued to drive home? Utilize any rideshare (Uber or Lyft) or Way to
                                                                                                       Go taxi to get home and to get back to work in AM. Keep receipts and turn
     HYPOkalemia (Replace if < 4.0)                                                                    into GME office for reimbursement
     -Si/Sx: Nausea, vomiting, weakness, muscle cramps. ECG with U waves, ectopy
     -Causes: Alkalosis (diuresis/vomiting), Acidosis (RTA, DKA), Cellular shifts
              (Insulin, catecholamines), mineralocorticoid excess, hypomagnesemia
                                                                                                    Depressed? Stressed? Overwhelmed? Feelings of hurting yourself?
              (must correct first), diuretics                                                       • EAP (Employee Assistance Program) - 24/7 availability: 1-800-437-0911
                                                                                                    • Page the on-call chief pager and talk about care for caregiver program
     TREATMENT:
     Choose route/formulation/dose: Can combine IV & PO if severe deficit,
              - For every 0.1 MM/L deficit, replace 10mEq of K                                      Adverse patient care event or unintended outcome? Near misses? Disrup-
              - Always replete the Mg before (or simultaneously with) K                             tive staff behavior? Medication errors? Equipment failures?
     • Tablet= KCl (K-Dur)= preferred, faster, less side effects, less dangerous.                   • VOICE reporting: anonymous system to help identify and fix system prob-
              Max dose = 60 mEq at a time. HUGE pill = DIFFICULT TO SWALLOW                             lems/failures or staff issues.
     • Powder= KCl (K-Lor)= same as K-Dur, but TASTES AWFUL, use if feeding tube                    • Go to Spirit homepage and in lower right corner under the “Quality and
     • IV= KCl or K+acetate= only use if NPO or severe deficit. Max infusion rate is                    Safety” section click “VOICE” and follow instructions
       10mEq/hr peripherally, 20meq/hr centrally (arrhythmias). Peripheral infusion
       often BURNS.
              Use K-acetate ONLY if pt has acidosis or hyperchloremia                               •   24/7 on-call chief: 708-643-0718
     Monitor/Reassess: Mild - q12hrs, Severe - q6hrs                                                •   Nkiru Osude (Loyola): 708-643-1625
                                                                                                    •   Stephen Morris (Hines): 708-643-4867
      Note:                                                                                         •   Colette Williams (Outpatient): 708-643-2309
      -ARF/CKD - be gentle (half dose or less, double interval, or don’t treat)                     •   Poornima Oruganti (QIPS): 708-643-2474
      -DKA - be aggressive (keep K >4-4.5mEq/L)                                                     •   Stefanie Milner (QIPS): 708-643-4334
      -Hypomagnesemia causes refractory hypokalemia
                                                                                                    •   Michelle Lundholm (Research): 708-643-8017

16                                                                                                                                                                        45
ENT PEARLS                                                   ELECTROLYTE DISTURBANCES
      Epistaxis                                                                               HYPOmagnesemia (Replace if  call ENT: cautery, anterior packing (+/- ABX), posterior                Can give up to 4g IVPB at a time
      packing (ICU monitoring)                                                                          • 1.6-2.0mg/dl give 2-4gm IVPB (usually infused at 1mg/hr)
      - Control BP, control coagulopathy as able                                                        • 1.0-1.6mg/dl give 4-8gm IVPB total, divide doses BID-TID
                                                                                                        • 2-2.5mg/dL)
      - Laryngectomies: NO connection b/t mouth and trachea (don’t bag mask the               -ARF/CRF - be gentle (half dose, double interval, or don’t treat)
      mouth to ventilate!)
      • Trach supplies
      - Know the trach details: Brand, Cuffed (DCT)/Cuffless (CFS), and Size
      - Have spare trach, obturator, inner cannula, and suction at bedside                    HYPOphosphatemia (nl = 2.6-4.4)
      • Trach fell out?                                                                       Causes: refeeding syndrome, DKA, Vit D deficiency, malabsorption, alcoholism,
      - w/in 1 week from placement → page ENT to replace!                                     inadequate TPN
      - > 1 week → can use obturator insert and replace yourself!
                                                                                              Complications of low phos: Skeletal, smooth and cardiac muscle issues due to
      • Complications                                                                         insufficient P causing low ATP levels > rhabdo, dia-
                 - tracheitis → ABX                                                           phragm weakness, arrhythmias, ileus
                 - mucus plugging → change inner cannula                                                                                                Phos equivalents:
                 - displacement/decanulation                                                                                                            8mmol = 14mEq
                                                                                              TREATMENT:
                 - bleeding < 48 hrs after placement → typically self-limited, procedural     • Neutraphos packet = 8mmol Phos + 7mEq K+
                 - bleeding > 48 hrs after placement → think sentinel bleed, TI Fistula!      • IV K+ Phos IVPB = 27mmol Phos + 40mEq K+
                                                                                              • IV Na+Phos IVPB available if need to replace Phos, but already high K+
                                                                                              Mild/Moderate (1.5-2.4mg/dL)
    Tracheoinnominate fistulas → ENT emergency!                                                     1-2 packets Neutraphos up to TID
                                                                                              Severe (
ELECTROLYTE DISTURBANCES                                                                               LOW URINE OUTPUT
                                                                                              Check for accuracy
     HYPOcalcemia                                                                                                                                Classification:
                                                                                              1) Foley? Improvement with flushing?
     - Causes: CKD, Vit D def., hypoparathyroidism, pseudo-hypoparathyroidism,                                                                     Oliguria: < 500 cc/day
                                                                                              2) In’s and Out’s
     “hungry-bone” syndrome, pancreatitis, citrate infusion (PRBC), rhabdo, TLS                                                                                    or
                                                                                              3) Incontinent / diaper?
      Correct for albumin or check an ionized calcium                                       4) Bathroom privileges?                                        350 place foley
     - Si/Sx: “stones” - nephrolithiasis / nephrogenic DI                                     6) Urine indices if AKI (Urine lytes, urea, osm, protein,
                                                                                                  cre; calc FENa, FeUrea)                                 FeNa= 2= ATN
                 “psychiatric overtones” - fatigue, confusion/AMS, depression                 Treatment:
                  Polyuria and dehydration                                                    1) If dry, replace fluids                                    FeUrea (used when on loop diuretics)
     TREATMENT                                                                                2) If intrinsic renal, work up                               350 cc PVR (make
     1.) Total Body Water (TBW) = weight (kg) x 0.6 for males or 0.5 for females                      sure pt was told to void prior to measuring PVR!)
                                (decrease to 0.5 and 0.45, respectively if elderly)           4) Hematuria
                                                                                                  Urology can see pt. in am unless patient is passing blood clots / mas-
     2.) Free H20 deficit (L) = [(Serum Na — 140) / 140] x TBW                                        sive bleeding
                                                                                              5) Scrotal pain
     3.) Correct Na by ≤ 0.5 mEq / L /hr (avoid cerebral edema / “locked in” syndrome)
                                                                                                  Get a scrotal US then call Urology
         Δ Serum Na per L fluid = (Serum Na — Fluid Na content) / (TBW +1)                    Note: Call urology immediately for urologic emergencies:
                                                                                              - Fournier’s gangrene, Testicular torsion, Priapism, Paraphimosis, Obstructing
     -Remember Na content changes depending the type of IVF (i.e. D5W, 1/2 NS, etc)           kidney stone
     -Increasing free H20 flushes for patients with tube feeds is also an option
     -Monitor levels frequently (q6 or 8 hrs) and adjust IVF rates accordingly

18                                                                                                                                                                                    43
GI BLEED                                                                    ELECTROLYTE DISTURBANCES
     1)   Upper (hematemesis, melena) vs. Lower bleed (BRBPR/ Hematochezia)- though                    HYPOnatremia
          some overlap                                                                                 - Excess H20 relative to Na, almost always driven by elevated ADH (appropriately
     2)   Hemodynamically stable (HR, BP)? Check orthostatics                                          or inappropriately)
                                                                                                       - Almost all cases are hypotonic hyponatremia or due to elevated glucose levels
     *Tachycardia and decreased UOP occurs before hypotension, if orthostatic consider
     ICU evaluation
                                                                                                                                              Serum Na 8 if active cardiac ischemia)                                  Hyponatremia
     5) Call GI Fellow
     6) PPI drip (pantoprazole 80 mg bolus x 1 + 8mg/hr IV x 72 hrs)—needs to be or-            Iso: hyperlipidemia or paraproteinemia                       Hypotonic Hyponatremia
        dered by GI fellow or pharmacy approval                                                      (MM / plasma cell dyscrasia)
     7) Start octreotide gtt if evidence of portal HTN/cirrhosis and evidence of UGIB                                                                        Urine Osm  6 units transfused                                            Hyper: ↑ BG, mannitol, sorbitol
     9) Dispo: Non-urgent → floor, Urgent → ICU, Emergent → scope ASAP
                                                                                                                                                       No                                 Yes

           ABDOMINAL PAIN & GI Sx                                                                                                                                             Excess Water Intake /
                                                                                                                                                                                 “tea and toast”

Questions: New? Recurrent? Blood? New medications? (opiates)
Don’t Miss:                                                                                                                                     Check urine sodium
1) Acute abdomen- Get acute abd series (upright CXR + 3 views of abd), Gen Surg consult
2) Ischemic bowel (pain > exam findings), leukocytosis, lactate elevation                                                       >30 mmol
ELECTROLYTE DISTURBANCES                                                                              PULMONARY FUNCTION TESTS
                                                                                                Spirometry:
                                                                                                FVC (%predicted):
     -HYPOnatremia (continued)                                                                        80-120 NL
                                                                                                      60-80 Mild
     TREATMENT                                                                                        40-60 Moderate
     -Asymptomatic or chronic: correct Na by ≤ 0.5 mEq / L /hr (avoid cerebral edema /
VENTILATORS                                                               ACID-BASE DISTURBANCE
     Initial Post-intubation Settings:
                Mode A/C                                                                    1) Acidemic or Alkalemic? [Normal pH (ABG)=7.40]
                Rate 12 (ideally, pt should take 4 breaths over vent/min)                   2) Primary disturbance respiratory or metabolic or both?
                VT     500 (6 cc/kg)                                                             HCO3- (BMP): ↑=met. alk.; ↓=met. acid. (normal=24)
                Flow 60                                                                            PaCO2 (ABG): ↑=resp. acid.; ↓=resp. alk. (normal=40)
                FiO2 100% (titrate down as able,
ACID-BASE DISTURBANCE (Contd.)                                                                        LVAD LOW-FLOW ALARM

     DIFFERNTIAL DIAGNOSIS                                                                  1.   Assess patient – EMERGENTLY (think STEMI page)
                                                                                                  a. Are they bleeding?
     AG Metabolic Acidosis (MUDPILES):                                                            b. What is their blood pressure (mean arterial pressure if no pulse)?
     Methanol (formic acid)                                                                       c. How do they clinically look like?
     Uremia                                                                                       d. What are the patient’s last lab results?
     DKA
     Paraldehyde / Propylene glycol                                                         2.   Page the Heart Failure (HF) attending physician
     Isoniazid / Iron overload                                                                    a. If no response after 10 minutes, page again
     Lactic acidosis (hypoperfusion or metfomin)                                                  b. If STILL no response, page another HF attending OR the CV surgery fellow on-call
     Ethylene glycol                                                                              c. You may also page the VAD coordinator (all numbers listed in Web On-Call)
     Salicylates (salicylic)                                                                3.   Report the following information to attending, fellow, VAD coordinator (get them ready
                                                                                                 beforehand)
     Non-AG Metabolic Acidosis (USEDCARS + infusion of acids):                                    a. Your assessment of patient (see above)
     Ureteral diversions (including fistulas)                                                     b. The latest LVAD parameters (Flow, Speed, Power, PI or PI amplitudes if HVAD)
     Sniffing glue                                                                                c. Trends of the MAPs and Flows
     Endocrinopathies (VIPoma)                                                                    d. Urine output
     Diarrhea                                                                                     e. Most recent last lab results
     Carbonic anhydrase inhibitors / Cholestyramine
     hyper-Alimentation (TPN)                                                               4.   You will likely have to Order the following, plus any other orders rec’d by the attending…
     Renal tubular acidosis                                                                       a. New set of labs including PT/INR
        Type: 1 (Distal) ↓H+ secr.; 2 (Prox) ↓HCO3 resorp.; 4 hypoaldosteronism                   b. ECHO to assess RV, LV fxn, inlet cannula obstruction
     Saline
     Infusion of HCl– or Ammonium Cl–
     Respiratory Acidosis:
     1. CNS depression (sedatives, CNS dz, obesity, hypoventilation)
                                                                                                         CARDIAC ARREST IN LVAD
     2. Pleural disease (ie PTX, or large effusion)
     3. Lung disease (COPD, ARDS, PNA, PE)
     4. Musculoskeletal (Kyphoscoliosis, Guillain-Barre, MG, botulism, myositis)
     Metabolic Alkalosis: (increased HCO3), almost always due to #1, #2, or #3
     1. Intravascular volume contraction (loss via GI, renal, resp, skin, or 3rd spacing)
     2. Hypokalemia
     3. Vomiting / NG suction
     3. Increased glucocorticoids or mineralocorticoids
     4. Alkali intake (HCO3 infusion, milk alkali syndrome)
     5. Bartter’s syndrome (genetic defect in Na/Cl/K pump– acts as loop diuretic)

     Respiratory Alkalosis (CHAMPS breathe fast):
     CNS (catastrophic CVA) or Cirrhosis
     Hypoxia / Hyperventilation
     Anxiety / Pain                                                                                                                                                       Refer to page 35 for
     Mechanical ventilation                                                                                                                                             the 5H’s and T’s; also
     Progesterone / pregnancy / pulmonary (fibrosis, edema, pneumonia)                                                                                                   include Thrombosis
     Sepsis / salicylates                                                                                                                                               of LVAD and empha-
                                                                                                                                                                          size Hypovolemia
                                                                                                                                                                           from GI bleeding

22                                                                                                                                                                                  39
LVAD PARAMETERS                                                                      INSULIN & GLYCEMIC CONTROL

  There are four parameters monitored on the HeartMate II: Speed, Flow, Power, and Pulsatility
                                                                                                                  Hypoglycemia:                                               Glycemic control goals:
  Index. No single parameter is a surrogate for monitoring a patient’s clinical status. It is important
                                                                                                                  1) Juice or 1amp D50                                        Floor: Premeal < 140
  to consider trends. Each patient’s values are specific to their pump.                                           2) Recheck Accucheck after 15min                                   Postmeal  INP Pharmacy Quick Order by Category > Diabetes
               If flow falls below 2.5 L/min, the device will alarm “low flow”                                                    medication: insulin > Insulin sliding scale/correction factor > follow prompts
                                                                                                                                    as indicated”
       Afterload Sensitive: If afterload (blood pressure) is high, the pump will not increase speed
                                                                                                                  - Insulin infusion: “INP Orders > Hines PROTOCOLS and PATHWAYS > Endotool Order
         to overcome the high outflow pressure. Because power demand is not increased, the dis-                                        Set > follow prompts as indicated”
         played flow read out may not change or, potentially, decrease, even though the true flow out             -Insulin pump protocol (any pt with pump requires endocrine consult):
         of the pump is hindered by the high aortic pressure                                                                          “Tools > Medical library/Clinical resources > Clinical protocol & pathways
       At any given speed, increased blood pressure will decrease flow!                                                              > Diabetes Mellitus protocol”

  PULSATILITY INDEX                                                                                               Loyola Insulin Protocols:
                                                                                                                  - Sliding scale: “Manage orders > Order Sets > search ‘IP INSULIN ADULT
       Pulsatility Index (PI) is the left ventricle’s (LV) pulsatile contribution to the pump:                                    SUBCUTANEOUS’ > follow prompts as indicated”
          LV full → greater stretch → greater contractility = ↑Pulsatility Index                                  - Insulin infusion: “Manage orders > Order Sets > search ‘Endotool’ > follow prompts as
          LV empty → less stretch → little contractility = ↓Pulsatility Index                                                          indicated ”
       PI as it relates to changes in patient’s status:
                                                                                                                  - Remember to have a hypoglycemia protocol ordered anytime there is active insulin order:
               Indicative of changes in volume status due to altered preload                                            - Hines: “INP Orders > INP Pharmacy Quick Order by Category > Diabetes
               indicative of changes to the natural heart’s contraction                                                           medication: insulin > Hypoglycemia protocol”
                                                                                                                          - Loyola: Imbedded within the above order sets
       PI as it relates to changes in pump speed:
               As pump speed is increased, the PI goes down
               As pump speed is decreased the PI goes up

  PI EVENT
       A PI event occurs when there is a 45% + or – change from the previous 15 second running
         average. Possible causes of events:

Suction Event: the                Dehydration,                   Arrhythmia,               Right heart failure,
inflow cannula is              bleeding, increased           Vasovagal response         Increased PA pressure
   obstructed                        diuresis

       If a PI event is detected, the pump speed will automatically reduce to the low speed limit and
         then gradually ramps back up at 100rpm/sec to the fixed speed.
     38                                                                                                                                                                                                 23
DYSPNEA
               DIABETIC KETOACIDOSIS
                                                                                                  1) Recent sedatives/narcotics?
                                                                                                  1) Recent respiratory treatments?
     Diagnosis is in the name: 1.) Hyperglycemia 2.) Anion gap metabolic acidosis                 2) Pulmonary edema/effusions—In’s and Out’s?
                              3.) +Ketones in urine or serum (β-hydroxybutyrate)                  3) Hypoxia?- Pulse ox correlate with the pulse? Test on your finger.
                                                                                                  4) Hypercapnea?- somnolence, asterixis, pursed lip, poor air movement–Get ABG
     Symptoms: abd pain, N/V, polyuria, polydipsia, dehydration, fatigue, weakness,               6) Do they have “the look”?
     AMS/coma, Kussmaul breathing (deep, rapid)
                                                                                                  Main Concerns:                            Diagnosis:
     Precipitants: Always need to work up the source! Remember the 6 I ‘s:                         PE                                     1) Listen to patient’s story/look at
              -Infection                                                                           Pneumothorax                               sign out
              -Inflammatory (i.e. pancreatitis/cholecystitis, etc.)                                COPD/Asthma                            2) Focused exam
              -Ischemia/Infarction (MI, colonic, stroke, etc.)                                     CHF/Pulm edema                         3) Stat CXR
              -Insulin non-compliance                                                              Large effusion                         4) ABG (hypoxia, hypercapnea)
              -Intoxication                                                                        Pneumonia/aspiration                   5) Supplemental O2
              -Iatrogenic (steroids)
                                                                                                  Treatment: Depends on etiology/severity
     Labs:
     • BMP: ↑ AG, ↓ HCO3, ↑ BG, ↓ or ↑ K, +/- ↑ BUN/Cr if severely dehydrated                      Duonebs up to q4h on floor, more often or continuous needs ICU transfer
     • UA: +Ketones or ↑ serum β-hydroxybutyrate                                                     Supp oxygen: NC / face mask > Ventimask > NRB > CPAP/BIPAP > Intubate
     • CBC: +/- ↑WBC                                                                                         Caution with high O2 in COPD—may decrease respiratory drive
     • Other diagnostic studies aimed at suspected precipitant (see above)                           Diuresis if overloaded—usually at least 40 mg IV lasix
     Treatment: Admit to ICU                                                                         BiPAP (start at IPAP 10/ EPAP 5) considered in the following:
     • Aggressive IVF (these patients are on average 5 L down, sometimes more!)                             a) COPD exacerbation
              - NS initially > 1/2 NS when euvolemic or Na normalizes                                       b) Pulm edema in CHF
              - Switch to D5 +1/2 NS when BG
PRE-OP CARDIAC RISK STRAT
                                                                                                                 SLEEP ISSUES
 1.) Emergent surgery? - acknowledge the risk and go to OR without further
                      testing                                                      1)   What has worked in the past?
                                                                                   2)   Any standing order for sleep meds?

 2.) Any very high risk features? - Rx as indicated prior to OR +/- cardiology     TREATMENT:
                                       consult                                     1) Lights off, TV off, relaxing environment
     • MI within 30 days                                                           2) Benadryl (diphenhydramine) 25-50mg PO/IV (avoid if >65yrs - anticholinergic)
                                                                                   3) Ambien (zolpidem) 2.5-10mg PO (caution if 1st time use)
     • Severe aortic stenosis                                                      4) Restoril (Temazepam) 7.5-30mg PO (caution in elderly)
     • Symptomatic mitral stenosis                                                 5) Haldol 1-2mg IV (useful in delirium, dementia, sundowning)
     • Decompensated CHF
     • Significant arrhythmia (Mobitz II, high grade AVB, CHB, new VT,             Note:
                               uncontrolled SVT with HR >100)                       Caution in elderly, risk of falls, MS changes, urinary retention
                                                                                      Avoid in liver failure
3.) Calculate RCRI score — low risk ( 2.0 mg/dL      • Two = 2.4%               Vital signs?    New change vs. Baseline?
                                                        • Three = 5.4%
                                                                                   Common in-hospital causes:
4.) RCRI score w/ elevated risk (≥1% or ≥1 RF)? -
Assess functional status                                                           -Head trauma/      -infection (CXR, Cx, U/A) -meds (anticholinergic, sedatives,
     • 1 MET = self care, dressing, toileting                                      falls                                        etc)
     • 4 MET = walking up 1 flight of stairs or level ground at 3-4 mph            -seizure           -toxic/illicits (UDS)     -hypoxia
     • 4-10 MET = gardening, sweeping, scrub floors, move furniture,               -stroke            -hypoglycemia             -hypercapnea (consider ABG)
                   ≥2 flights of stairs                                            -hypotension       -hepatic encephalopathy -sundowning
     • ≥ 10 MET = swimming, tennis, competitive team sports, jogging               -bradycardia       -uremia                   -ICU psychosis
                   9:00 mile                                                       -bleeding          -other metabolic

5.) Function capacity ≥ 4 MET? — no further testing, proceed to OR                 WORKUP:
                                                                                   1) Neuro exam
                                                                                   2) O2 sat and Accucheck
6.) < 4 MET or unknown?                                                            3) CT head if ANY focal findings (esp. with head trauma)
     • Will further testing impact OR decision making?                             4) Other work-up directed at suspected etiologies on above DDx
     • Further cardiac evaluation and intervention (i.e., stress testing and PCI
        for new ACS/UA, etc.) only for standard indications in the absence of      TREATMENT: Directed at suspected causes above. Consider:
                                                                                   1) Narcan 0.1-0.2mg IV q2-3mins PRN, if suspect narcotic OD
        the proposed surgery*                                                      2) Flumazenil 0.2-0.5mg IV q30-60 seconds PRN, if suspect benzo OD (be careful
     • If it will not change OR management, proceed to OR                             in chronic benzo pts, alcoholics, seizure history as can predispose to seizure)
     • If it will, can pursue stress testing and if abnormal can consider          3) Haldol 2mg IV/IM/PO if agitated (Do NOT use if QTc >500ms)
        re-vascularization prior to OR. If normal, proceed to OR                   4) Turn off TV / lights etc. at night
                                                                                   5) Consider 1:1 sitter or restraints

*This is because studies have shown re-vascularization (PCI or CABG) prior
to OR does not improve peri-operative outcomes

 36                                                                                                                                                                  25
PAIN CONTROL                                                                 CHADSVASC / ANTI-COAG “BRIDGING”
     General guidelines (what was tried before?):                    - Acute mild-mod pain: trial of
     ▪Pain >7 increase prior dose by 50% to 100%                                                        -Risk calculator for annual stroke risk in patient’s with AFib (higher score = higher risk)
                                                                     non-opiates > escalate prn
     ▪Pain 4-7 increase dose by 25% to 50%                           - Acute severe pain: short
     ▪Pain
POST-CATH GROIN CHECK                                                                                                   FALLS
          *The main purpose for groin check is to rule out a large bleed
Exam:                                                                                             1)     Go see the patient
• A post-cath groin should be soft, normal-colored, minimal to no bruising and only mildly        2)     Were guard rails up? How high is the bed?
  tender
• Check for oozing– a small amount is okay– consider bandage change, but call your senior         Assessment:
  or the cards fellow if concerning                                                               1) Neuro exam
                                                                                                  2) Consider CT head if: anticoagulated (incl ASA), Head trauma, AMS, Neuro deficits
• Check pulses (posterior tibial & dorsalis pedis)- compared to Pre-cath exam H&P note            3) Document incident as a cross-cover / progress note (at VA use Fall template)
          • Loss of distal pulses could be compression of femoral a. by large hematoma            4) Ensure Fall precautions are ordered and maintained
• Listen for bruit– suggests fistula
          • if present, may need U/S in AM as determined by primary team
          • Most small bruits resolve spontaneously
• Assess for hypotension or back pain
          • Acute hypotension +/- back pain should be assumed to have RP bleed                                 FEVER (>38 C or 100.4 F)
                     • Apply FIRM (will hurt your hands and the patient), occlusive pressure
                        PROXIMAL to site of needle insertion
                     • CALL cards or interventional fellow IMMEDIATELY if this occurs             1)     Is this new?
                                                                                                  2)     When were last cultures sent?- if not in the last 24hrs, probably want to re-culture
                                                                                                  3)     Is this neutropenic fever? (ANC < 500, do not do internal rectal exam, but do
                                                                                                         visual exam for peri-rectal abscess)
                 ATRIAL FIBRILLATION                                                              4)
                                                                                                  5)
                                                                                                         Are antibiotics already on board? Are there holes in coverage?
                                                                                                         Has the patient received Tylenol/ibuprofen?
                                                                                                  Causes: “The 5 W’s + M”
Diagnosis: -Irregularly irregular rhythm on exam                                                   Wind: pneumonia, atelectasis
             -EKG: no p-waves or “fibrillating” baseline before QRS complex
                     that are irregular                                                              Wound: surgical site, pressure ulcer, IV phlebitis
Etiology: ~50% without regularly identifiable cause                                                  Water: UTI
           - CHF exacerbation, ischemia, ↑ BP
           - Hypoxia, anemia, COPD, PNA, PE, OSA                                                     Walk: DVT, hematoma
           - Infection, post-op (esp. cardiac surgery), hyperthyroidism, electrolytes issues         Wonder drug: Carbamazepine, phenytoin, Phenobarb, beta-lactams, nitrofurantoin,
           - Alcohol, drugs (cocaine, amphetamines), caffeine                                          sulfa, allopurinol, bleomycin, NMS, serotonin syndrome, etc.
           - Intracranial processes (SAH or ischemic stroke)
- Work up (if new): EKG, CXR, BMP, CBC, Mg, TFTs
                                                                                                     Malignancy: lymphomas, renal and hepatic tumors
- Troponin is not necessary unless there are other ischemic symptoms                              WORKUP: (perform if not done within 24hrs)
- Further work up based on suspected etiology                                                     1) Blood cultures x 2 different sites (4 bottles total)
                                                                                                  2) U/A and urine culture
Treatment: - 2 main goals: 1.) Rate or rhythm control 2.) Decreasing stroke risk                  3) CXR (PA & Lat preferred)
            - No mortality difference between rate or rhythm control                              4) Examine external sites (lines, ulcers, wounds)
            - Goal HR in rate control strategy is
EKG INTERPRETATION
                                 NEUROLOGY
STROKE                                                                                                 Location         Coronary supply                             EKG leads
-Si/Sx: dysarthria/aphasia, facial asymmetry, limb weakness/numbness, imbalance/clumsiness
-What to do immediately:                                                                               Septum           LAD, posterior interventricular             V1, V2
           1.) Have RN call CODE STROKE                                                                Anterior         LAD                                         V3, V4
           2.) Information to have for stroke team: Brief HPI, last known normal, POC glucose
                level, creatinine, INR, medication list including blood thinners                       Lateral          Circumflex, LAD                             I, AvL, V5V6
           3.) If hypoglycemic, give thiamine 100mg IV + D50 1 amp IV STAT                                                                                          II, AvF, III, con-
- Imaging orders (discuss with neuro first): CT head non-contrast stat, if (-) —-> CT head             Inferior         RCA, R marginal                             sider right-sided
  perfusion and CT angio head & neck stat                                                                                                                           EKG
                                                                                                                        Circumflex, RCA, PDA                        V1-V3, consider
SYNCOPE (adapted from JACC 2006)                                                                       Posterior
                                                                                                                        (PDA= Posterior Descending Artery)          posterior EKG
                                                                                                       Anatomy           Coronary supply
                                                                                                       RA               RCA
                                                                                                       RV               RCA, R marginal, LAD
                                                                                                       LA               Circumflex
                                                                                                       LV               LAD, diagonal, L marginal, circumflex
                                                                                                       SAN              RCA (60%), LCA (40%)
                                                                                                       AVN              RCA (80%)
                                                                                                       Bundle           LAD

                                                                                                       7) Blocks
                                                                                                        1° AV: PR>200ms
                                                                                                        2° AV Mobitz type I (Wenckebach): progressive PR prolongation before dropped QRS
                                                                                                        2° AV Mobitz type II: dropped QRS w/o PR prolongation
                                                                                                        3° AV: complete block, P wave/QRS dissociation
                                                                                                        RBBB: (precludes RVH diagnosis)
                                                                                                         1) QRS >120ms (incomplete RBBB if QRS  120ms (incomplete LBBB if QRS  if hypoglycemic, give thiamine 100mg IV + D50 1 amp IV STAT                             5) +/- PRWP, LAD, Q waves in inferior leads
- Labs: CMP, CBC, UDS and AED levels if appropriate                                                     Left Anterior Fascicular Block
- If persists >3 min —> Lorazepam 2 mg IV stat (if no IV access, Midazolam 10 mg IM stat)                1) QRS
EKG INTERPRETATION
                                                                                                                            ALCOHOL WITHDRAWAL
1) RATE: Normal 60-100bpm, bradycardia < 60bpm, tachycardia >100 bpm
                                                                                                                                                                            Major Symptoms:
                                                                                                          1)   When was their last drink?
                               Box counting method (1 large box)                                          2)   What is their risk for withdrawal?                              Seizures (6 - 48 hrs)
                                                                                                               Alcohol consumption > 3 – 4 times per week
 1 = 300 BPM       2 = 150 BPM     3 = 100 BPM     4= 75 BPM     5 = 60 BPM      6 = 50 BPM
                                                                                                          
                                                                                                                                                                               Hallucinations (12 - 48 hrs)
                                                                                                               Consumption of 5+ drinks on one occasion
                                                                                                               History of morning drinking                                    Delirium (48 - 96 hrs)
2) RHYTHM                                                                 1 small box = 1 mm = 40 msec         History of impaired control over drinking                      Autonomic instability / fever (DTs)
    Sinus: upright P wave before every QRS                              1 large box = 5 mm = 200 msec        History of withdrawal episodes or seizures
                                                                                                               Current abuse history of other drugs                        Minor Symptoms: (Starts in 6-36 hrs)
   Junctional: regular retrograde or hidden P waves all leads
   A-Fib: irr. irregular, P wave ~350-600bpm, QRS ~120-180bpm                                           If +sx or “at risk” for withdrawal, start treatment
                                                                                                                                                                             Tremor
   A-Flutter: regular or irreg P wave ~250-350bpm, saw tooth                                            **At HVA: use “Alcohol Withdrawal Protocol Order Sets…”      Irritability
                                                                                                          **At Loyola use an order set “IP ICU ALCOHOL WITHDRAW-  Anorexia / Nausea
   SVT: regular, retrograde P waves, QRS ~150-250bpm                                                    AL PROTOCOL” or “IP NON-ICU ALCOHOL WITHDRAWAL
   MAT: ≥ 3 different P wave morphologies, QRS ~100-200bpm                                              PROTOCOL”.**
                                                                                                          Protocol includes:
   PAC: P wave and QRS are early but morphology normal                                                  1) Benzodiazepines, titrate to calm patient
   PVC: QRS early and wide without preceding P wave                                                                Ativan 1-4mg PO/IV q2hrs PRN
                                                                                                                     Librium 50-100mg PO PRN (max: 300mg/day)- avoid in liver dz
   VT: ≥3 consecutive PVCs, 120-200bpm, unlike SVT has wide QRS and is slightly
     irreg. (Non-sustained VT: < 30 sec, Sustained VT: > 30 sec)
                                                                                                          2) Fluids and vitamins
   Torsades de pointes (polymorphic VT): spiraling VT                                                      If can take PO= oral fluids + 100mg PO thiamine + 1mg PO folate + daily MVI
                                                                                                             If needs IV= Banana bag = 1L D5 + 100mg thiamine + 1mg Folate + IV vitamins
3) AXIS
    Normal ( –30° to +90°)                                                                              3) Nursing monitoring for s/s of worsening withdrawal or oversedation (CIWA)
   Usually normal if + deflection in both I and aVF                                                     Other considerations:
                                                                                                          -elevated BP in the setting of worsening withdrawal sx should be treated as
4) INTERVALS                                                                                              withdrawal with benzos rather than with antihypertensives
      PR 120-200ms                                                                                      -for autonomic instability consider clonidine start 0.1mg PO q6hr, titrate up
                                                                                                          -if refractory, consider using propofol or precedex or barbiturates in ICU
     QRS 60-120ms
     Prolonged QT: QTc >440ms,concern when >500ms
       (Eye ball test: is the QT >50% of the R-R interval)

5) CHAMBER ENLARGEMENT
                                                                                                                                                ANEMIA
                                                                                                          Check Retic Index= (retic count x Pts Hct/normal Hct) /maturation factor
                                                                                                          Maturation factor for given Hct: 45%=1.0, 35%=1.5, 25%=2.0, 20%=2.5
 LVH                                         RVH
 1) R in V5 or V6 + S in V1 or V2 > 35mm     1) Right axis deviation > +100°                              • RI >2% HIGH = Increased destruction or loss
 2) R in aVL > 11mm; R in I > 14mm           2) R > S wave in V1                                                    - Hemolysis (high LDH, high bili, low hapto)
 3) Left axis deviation < -30°               3) S in V5 ≥ 7mm or R in V1 > 7mm                                      - Acute blood loss (s/s of bleeding)                     nl abs retic ct = 50K. Should go
 4) Cornell: S in V3 + R in aVL >24 (men)    4) R in aVR ≥ 5mm                                            • RI 20 (women)                                                                                         HIGH MCV = Folate def, B12 Def, Liver dz, ETOH, hypothyroid,
 LAE                                         RAE                                                           meds
 1) Can fit >1 small box in 2nd phase of     1) Can fit >1 small box in 1st phase                          NL MCV = Sideroblastic, AoCD, microcytic overlap/pure red cell aplasia
    P wave in V1                                of P wave in V1                                            LOW MCV= IDA, thalassemias, normocytic overlap
 2) Biphasic P wave >120ms in II             2) P wave height >2.5mm in II
5) QRST CHANGES                                                                                                                            Fe         TIBC       Ferritin    % Iron sat
     ST Elevation DDx: AMI, pericarditis (diffuse STE), early repolarization, coronary                                 IDA                                              < 18%
       spasm, ventricular aneurysm (chronic persistent STE)
     ST Depression DDx: ischemia, digoxin effect, hypokalemia ( +/- U wave)                                            AoCD                                             > 18%
      Q waves:  Significant if: (never normal in V2, V3, or V4 regardless of size)                                     Thalassemias      nl         nl         nl          -
          1) > 0.04 sec in duration
          2) Depth >25% height of R wave in that complex                                                                 Sideroblastic               nl                    -

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