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Chapter 7

Health and Management Techniques
                                               Michelle Arnold, Roy Burris, and Lee Townsend

A      healthy, disease-free herd is a goal
       for all beef producers. A herd health
program will be most successful when it is
                                                 lighter, weaker calves at birth, which can
                                                 lead to a higher death loss, and more
                                                 susceptibility to diseases such as scours.
                                                                                                 vening. Calving difficulty often occurs in
                                                                                                 mature cows when calves present back-
                                                                                                 wards (dewclaws are pointed up), breech
customized to meet the herd’s needs. Lo-         Pregnant animals in poor condition be-          (tail first and no legs), or malpositioned
cal veterinarians are knowledgeable about        fore calving provide inferior colostrum         legs or head. If the heifer/cow is not mak-
diseases in the area and should be able to       and have lower milk production. This            ing progress, she should be quietly moved
make cost-effective recommendations.             can lead to lighter weaning weights or          to a facility to adequately restrain her for
Plan a program that prevents diseases and        fewer pounds of calf to sell. Females in less   examination. Clean the area around the
disorders; do not depend on a veterinar-         than desirable body condition at calving        vulva with soap and water. Use plastic
ian just to treat problems.                      are slower to return to estrus. Therefore,      obstetrical sleeves; bare hands and arms
  Requirements for a successful herd             body condition at calving affects the           are not recommended in case potentially
health program include:                          current calf crop (milk production) and         contagious organisms are present. Plenty
• Adequate handling facilities                   next year’s calving date (due to a later        of lubrication should be used to protect
• Good nutrition, especially with trace          rebreeding date).                               the vaginal area. A calf can generally be
   mineral supplementation                          Spring calving herds will also require a     delivered with firm, steady traction if the
• A working relationship between pro-            high magnesium supplement to prevent            head and both forelimbs are in the birth
   ducer and veterinarian (valid veteri-         grass tetany or “hypomagnesemia” (see           canal. If the calf is too large, the head and
   nary-client-patient relationship)             “Forage-related Disorders” later in this        legs will not be able to enter the birth canal
• A willingness to follow a program once         chapter for specific information on mag-        and a Caesarean section must be consid-
   it is established                             nesium requirements).                           ered. Prolonged efforts with no progress
• A management level that reduces stress            Environment has an impact on calf            can lead to a dead calf and cow. If you
   in cattle                                     survival. Calves born into a filthy envi-       cannot correct a problem after 30 minutes
                                                 ronment (muddy lot) have the energy             of trying, you should call for veterinary
   Several management techniques in-
                                                 drained from them quickly if cold and wet       assistance to assess the situation. Bear in
cluding identifying, implanting, vaccinat-
                                                 and bacteria can easily invade the navel.       mind that cows assisted early (within 90
ing, castrating, and dehorning, should be
                                                 A calf has little stored energy reserves        minutes) have a 16% higher pregnancy
done in as timely and humanely a manner
                                                 and needs this energy to stand and nurse        rate at pregnancy check but every hour a
as possible. Having a controlled breeding
                                                 shortly after birth. A clean, dry pasture       cow spends stuck in Stage 2 labor delays
season simplifies timing of vaccines. As
                                                 for calving is ideal if there is shelter and    rebreeding by four days.
discussed in Chapter 4, adequate han-
                                                 a catch pen so the cow can be restrained           During gestation, the placenta of the
dling facilities are necessary to properly
                                                 if calving assistance is required. Research     cow effectively separates the blood of the
restrain the animals for vaccination and
                                                 has shown that when cattle are fed in the       fetus from that of the dam and prevents
treatment. Work carefully when pro-
                                                 early evening (5 p.m.to 6 p.m.) during the      any transfer of protective immunity while
cessing cattle. If trying to set a record
                                                 last few weeks of pregnancy, more cows          in the uterus. Therefore, the calf is born
for speed, cattle may be unduly stressed
                                                 will calve during daylight hours, making        completely dependent on the absorption
or injured. Cattle can be worked rapidly
                                                 calving problems easier to identify.            of maternal antibodies from colostrum af-
enough when they are handled skillfully
                                                                                                 ter birth. Colostrum is the milk produced
and gently and when the handling facility        Calving Difficulty                              from the mammary gland in the first 24
is constructed so that cattle flow through
                                                   Observe heifers and cows for signs            hours after birth. A calf ’s gastrointestinal
it easily. Remember that animal health
                                                 of calving difficulty. Allow a reasonable       tract is designed to temporarily allow the
products, such as vaccines and implants,
                                                 amount of time for a cow to deliver on          absorption of antibodies (immunoglobu-
must be administered properly to be
                                                 her own, approximately two hours from           lins) from the small intestine, called “pas-
effective. Therefore, emphasize proper
                                                 appearance of the water bag to delivery of      sive transfer.” Passive transfer only occurs
technique rather than speed. Vaccines
                                                 the calf. Intervention is necessary if either   during the first 24 hours after birth; it is
do not work in animals that are chroni-
                                                 the water bag or feet have been visible for     most efficient in the first four hours of life
cally diseased, in poor nutritional status,
                                                 more than one hour with little or no prog-      and declines rapidly after 12 hours of age.
stressed, ill, or heavily parasitized.
                                                 ress or if actively straining for more than     At 24 hours, the gut is completely closed
Pre-calving Check                                30 minutes without making visible move-         and there is no further immunoglobulin
                                                 ment of the calf. Heifers should be allowed     absorption. These absorbed antibodies
  Spring calving cows, particularly heif-                                                        must be consumed in order to protect
                                                 no more than one hour to deliver the calf
ers, in poor body condition are at risk                                                          the calf from disease-causing organisms
                                                 once the water bag is visible before inter-
for calving problems. The result may be
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until its own immune system becomes              they contain less than 50 mg IgG per dose
                                                                                                 Example of a Culling Order
functional. Early suckling of good quality       and have no added nutritional value.            • Disposition
colostrum is essential for survival.                                                             • Pregnancy status
   The inability of the calf to get adequate     Annual Cow Evaluation                           • Structurally unsound/chronic
colostrum after birth can lead to “failure of       A cow should be evaluated every year           condition
passive transfer” (FPT). If the calf is weak     to determine if she can continue in the         • Age
                                                                                                 • Poor performance
at birth, especially if it has a swollen head,   herd. Seven quality checks are designed to      • Phenotype
or was manually delivered from a heifer,         determine her potential for reproductive        • Bred cows over 9 years of age
an oral calf feeder can be used to provide       success and detect any physical condi-          • Replacement heifers
the necessary colostrum to the calf. The         tions that might cause future problems.         • Bred cows 3-9 years of age
oral calf feeder (esophageal feeder) should      Pregnancy check is an ideal time to evalu-
be used on a calf positioned with the head       ate these seven areas.
bent down at a slight angle (nose below          1. Pregnancy. If not pregnant, cull at ap-     those cattle in the herd with the least
the ears), the ball should be lubricated             propriate time to reduce feed costs.       chance of being productive in the long
(vegetable oil), and you should see or feel      2. Disposition. Flighty cows that are dif-     term or farthest away from being produc-
the ball on the left side of the neck when           ficult to move into working pens and       tive. Equally important are factors such as
properly positioned (Complete instruc-               chutes often produce calves with the       disposition and phenotype that affect the
tions may be found in the section on calf            same traits. Culling troublesome cows      marketability of offspring. The following is
scours). Colostrum from your farm is the             will select for good disposition in the    a list of factors to consider when deciding
best one to use because it has antibodies            herd.                                      who to cull this year.
against the diseases found on the farm           3. Eyes. Check for “cancer eye.”                  Disposition. A cow’s attitude is an im-
however good powdered colostrum                  4. Feet and legs. Check for lameness or        portant consideration in any cattle op-
replacement products are commercially                poor conformation.                         eration. Bad behavior has both a genetic
available.                                       5. Udder. Check for dry or light quarters,     component and is also learned by calves
   A mature cow has more concentrated                poor conformation and large, pendu-        at an early age. Mean cattle are dangerous
antibodies (immunoglobulins) in colos-               lous teats that make nursing difficult.    to people, damage facilities, tear up fences
trum than a heifer; the concentration of         6. Body condition score (BCS): This should     and make gathering and working cattle a
immunoglobulins is highest immediately               be between 5 and 6 in an adult cow.        nightmare. Remember a good cow can
after calving and decreases over time.           7. Mouth: Check if older cow or low BCS        be protective without being dangerous
Colostrum can be frozen and kept until               for teeth problem; “smooth-mouthed”        and destructive.
the next calving period but no longer than           or “broken-mouthed” will require feed         Pregnancy Status. A cow should produce
one year. Be careful to freeze it in small           supplementation to maintain body           a calf at least once a year and the sale of
amounts and not in one large gallon jug.             weight.                                    that calf needs to pay her way. Diagnosing
Frozen colostrum must be slowly thawed                                                          a cow as “open” (not pregnant) is as simple
out in a warm water bath and not placed          Deciding Who to Cull                           as a veterinarian palpating for pregnancy
in the microwave to thaw. Be cautious               Every year, the cow-calf producer           at least 40 days after breeding or removing
about using another farm’s colostrum,            needs to critically evaluate each animal       the bull. A simple, inexpensive blood test
especially from a dairy, because of the risk     in the herd and decide if she is paying her    can also be used 28 days post-breeding
of acquiring Johne’s disease and bovine          upkeep. Open cows (those that are not          to determine pregnancy status. If many
leukosis virus.                                  pregnant) at the end of breeding season        cows are found open at pregnancy check,
   Numerous colostrum replacements               obviously are the top of the cull list. With   work with a veterinarian to determine
are available on the market. The use of          variable costs running $400-$500 per year      if reproductive disease, poor nutrition,
a colostrum replacement product offers           per head, breeding stock depreciation          bull infertility or inability was the cause.
a convenient method to improve pas-              running another $100-$150 per year, and        Remember that cows that calve late in
sive immunity by mixing a powdered               an additional $100-$300 in fixed costs         the season have less opportunity to breed
commercial product containing bovine             (2017 estimates), keeping open cows is a       back in a controlled (for example, 90 day)
IgG with water and feeding the calf. A           financial black hole. Beyond pregnancy         breeding season. Summer heat and fescue
colostrum replacer contains a minimum            status, what other variables are important     toxicosis can be important contributors to
of 100g of IgG per dose, protein, miner-         to evaluate? Structural soundness, body        low conception rates.
als, vitamins, and energy and is designed        condition score, age, performance, and            Structural soundness/chronic conditions.
to be fed when no maternal colostrum             disposition are vital components in de-        Bad hooves or claws, lameness due to
is available. This should not be confused        veloping a culling order. This culling order   hip/knee injury, eye problems, and poor
with a colostrum supplement product              is exceptionally important during times        udder conformation are all examples of
that is designed to be fed in addition to        of drought or a year with marginal hay         structural problems that adversely affect
and after natural colostrum. Colostrum           production because deeper culling may          performance (Figure 7-1). Good feet and
supplements are significantly less expen-        be required to manage through a difficult      legs are essential for weight maintenance,
sive than replacement products because           season. To begin, it is best to think about    breeding, calving, self-defense, and raising
                                                                                                a calf. The udder should be firmly attached
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with a level floor and high enough that newborn calves can eas-               Figure 7-1. Udder scoring system for beef cattle.
ily find and latch onto teats. Cows with blind or light quarters,                                          Description
funnel or balloon shaped teats, or any history of mastitis are                 Score        Udder Suspension                        Teat Size
strong candidates for culling.                                                   9             Very tight                           Very small
   Cows with chronic conditions that will not improve such
as progressive weight loss, early cases of cancer eye, repeated
episodes of vaginal prolapse during pregnancy, and extreme sen-
sitivity to the effects of fescue toxicosis should be removed from
the herd as soon as the calf is weaned. Cows with confirmed
disease conditions such as Johne’s disease, bovine lymphoma,
or advanced cancer eye should not be returned to a com-
mercial market as breeding stock. The most common reasons
                                                                                 7                  Tight                             Small
for carcass condemnation at slaughter include emaciation,
lymphoma, peritonitis, cancer eye, blood poisoning, bruising,
and other cancers.
   Age. Cows are considered most productive between 4-9 years
of age. Look at the teeth to assess the age but evaluate them in
light of diet-cows that eat gritty or sandy feeds and forages have
increased tooth wear beyond their years (see “Estimating Age
of Cattle by Their Teeth” later in this section). Cows with badly
worn or missing teeth will have a hard time maintaining body                     5             Intermediate                     Intermediate
condition. Older cattle die of natural causes, too.
   Poor Performance. Record keeping is an invaluable tool for
evaluating performance. Readable visual tags on both the cow
and calf allow matching of calf sale weights to the dams and
identification of cows that did not produce a calf. Inferior genet-
ics and poor milk production produce lightweight calves that
do no grow well. An overweight cow or large framed cow with
a small calf that doesn’t grow and gain weight usually means the                 3               Pendulous                            Large
cow is not producing much milk. Sick baby calves may be an
indication of poor quality colostrum and poor mothering ability.
   Phenotype. These are cows that do not “fit” the herd because
of external features such as unusual breed, size, muscling and
color. These challenges may be overcome to some degree by
choice of sire to balance out the unwanted traits. Remember
that buyers of commercial calves look for uniformity in color,
weight, and frame in a set of calves.
   The last ones to go. Hopefully culling will never have to go                  1            Very pendulous               Very large, misshapen
this deep in the herd. Bred cows over 9 years old, replacement
heifers (especially those that did not breed in the first 30 days),
and bred cows 3-9 years old should be the last sold. Thin cows
that conceive late in the breeding season should go first.
   Since 20% of gross receipts in a typical cow-calf operation come
from the sale of cull animals, pay attention to price seasonality and
body condition score before sending these animals to market.
Prices are highest in spring and lowest in late fall/early winter when        American Hereford Association; BIF Guidelines, 2020
spring born calves are weaned and culls sent to market. Adding
weight and body condition to culls is an opportunity to increase
profitability but can be expensive. Work with a nutritionist to                Cull Cow Language
come up with realistic cost projections before feeding cull cattle             • Breakers (75-80% lean): Highest conditioned cull cows (BCS ≥
for a long period of time.                                                       7), excellent dressing percentages
                                                                               • Boners or “boning utility” (80-85% lean): Moderately
   When it comes to making decisions on who to cull, remember to                 conditioned (BCS 5-7), well-nourished commercial beef cows
consider functionality in the environment. Is she an “easy keeper?”              (usually highest price cull)
Does she keep flesh and condition and raise a good calf, even when             • Leans (85-90%): Lower BCS (1-4), lower dressing percentages,
feed and forage is limited? On the opposite side, does she give too              susceptible to bruising during transport and expect more
much milk or is her frame size so large that you can’t keep weight               trim loss. Moving cows from lean to boner status can usually
                                                                                 be done efficiently
on her, even when pasture is plentiful? Is her pelvis so small and

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tight that calving is a problem and will be    Table 7-1. Sample cattle working schedule.
a problem in her offspring? Functionality      Time                  Calves                                    Cows/Bull
leads to longevity and improved efficiency.    Birth                 • Identify
By retaining more young cows in the herd,                            • Record birth date, dam
you can decrease the number of replace-                              • Castrate (delay 12-24 hours for
ment heifers needed and cull cows that are                             bonding with dam)
                                               Prebreeding           • Vaccinate 7-way clostridial             • Vaccinate IBR/PI-3/BVD/BRSV,
only marginally profitable. Young cows also
                                                                       (Blackleg)                                Lepto-5, Vibrio, Pinkeye
increase in value as they mature because                             • Pinkeye vaccine in the spring           • Deworm
the body weight of the cow and her calf’s                            • Castrate/dehorn if needed               • Sort into breeding groups
weaning weight will continue to increase                             • Implant male feeder calves if           • Bull breeding soundness exam
from 2-5 years of age. Longevity may also be                           castrated
improved through crossbreeding because         Midsummer1            • Deworm2                                 • Deworm2
                                                                     • Reimplant steers according to           • Remove bull from spring
hybrid vigor adds essentially 1.3 years of                             label directions                          breeding herd
productivity or one more calf per cow.             Preweaning        • Vaccinate: IBR/PI-3/BVD/BRSV            • Pregnancy examination
   In summary, a herd of easy-keeping,                               • Booster 7-way clostridial vaccine       • Evaluate cows for problems
efficient cows is possible through rigorous    Weaning (after        • Booster IBR/PI-3/BVD/BRSV               • Sell open and cull cows
culling and careful selection of replace-      stress is over)       • Treat for internal and external         • Treat for lice and grubs in late fall
ments. Matching genetics to management                                 parasites
and environment results in maximum ef-         Before calving                                                  • Vaccinate against scours
ficiency, longevity, and, ultimately, maxi-    ¹   Avoid working cattle during periods of extreme heat; early morning is best.
                                               ²   Use a dewormer that is effective against inhibited Ostertagia larvae.
mum enjoyment of cattle production.

Vaccinations                                   Table 7-2. Modified-live versus killed vaccines.
   Your veterinarian can provide valuable                            Advantages                         Disadvantages
advice to develop a vaccination program        Modified-live         • Single dose can provide          • May cause abortion in pregnant
to prevent contagious diseases for your par-   vaccine                 protection                         animals
ticular herd. The time of year you calve and                         • Less expensive per dose          • Need to be reconstituted before
                                                                     • More rapid immune response         use
when you prefer to work them will influence                          • More natural and complete        • Inactivated by heat and sunlight
the program for your herd. Table 7-1 is an                             immune response                  • Partial bottles cannot be stored
example of a Cattle Working Schedule, in                             • Longer-lasting protection        • Must be used within 1-2 hours
which cattle are gathered five times a year.                                                              after mixing
   Vaccination is a tool that is used          Killed                • Can safely be given to any       • Increased adverse reactions
                                               (inactivated)           animal at any stage of pregnancy • More expensive
alongside other management tools such
                                               vaccine               • Stable in handling and storage   • Needs 2 doses initially to be
as forage management, proper nutri-                                                                       protective
tion, maintaining a clean environment,                                                                  • Shorter protection time
biosecurity, and stress management.
Vaccination programs are designed to
protect the herd against disease caused        stimulate the immune system similar                    immune system to respond to the vaccine
by infectious organisms, such as viruses       to a natural infection. In general, MLV                challenge. Table 7-2 lists the advantages
or bacteria. Vaccines contain either killed    stimulate a longer-lasting immunity than               and disadvantages of killed and modified-
or modified live organisms that do not         killed vaccines. However, MLV may cause                live vaccines.
cause disease. These vaccine organisms         abortion if given improperly to pregnant                  Vaccines are available for many disease
stimulate the animal’s immune system           cattle. Most modified-live vaccines must               conditions. However, many diseases do
to “remember” how to mount a response          be reconstituted by adding sterile water               not routinely threaten most beef herds,
if it is later infected with that organism.    (diluent) to a dehydrated “cake” in a                  and some vaccines are not sufficiently ef-
A vaccine cannot prevent infection but         separate sterile vial. Once mixed, the vac-            fective to justify their use. Therefore, only
will allow the animal to recognize and         cine organisms are fragile and survive for             the most significant vaccines are included
respond more quickly to infection, lessen-     only 45 minutes if in direct sunlight and/             in a routine vaccination schedule. In the
ing the severity of disease.                   or heat. Use a cooler to protect vaccines              young animal being vaccinated for the
   Most vaccines contain either modified-      from extremes of cold or heat and from                 first time, a second or “booster” vaccina-
live or killed organisms or a combination      sunlight. In a cooler, MLV organisms can               tion is often required a few weeks after
of the two. Modified-live vaccines (MLV),      survive approximately one to two hours.                the first vaccination to properly prime
both for viruses and bacteria, replicate          Killed vaccines contain organisms or                the immune system. This is exceptionally
(multiply) in the animal after injection.      subunits of organisms that do not repli-               important if using killed vaccine. Label
The organisms have been modified so            cate (reproduce) in the animal after injec-            directions must be followed to obtain the
that they do not cause the disease but         tion. Killed vaccines contain an adjuvant              desired immune response.
                                               (added substance) that stimulates the

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Vaccinations for the Cow-                      • Breeding Soundness Exams are highly                herd, testing all calves is the proven
Calf Operation                                   recommended for herd bulls and                     first step to find persistently infected
   One of the most common questions              should be conducted 60-75 days prior               (PI) animals
in cow/calf production is what vaccines          to turnout (see Chapter 5, “Managing
are necessary on an annual basis in              Reproduction”). Bulls need the same           Calves 2-3 Weeks Pre-weaning
Kentucky to keep the herd healthy. The           vaccinations and deworming as the             • Viral respiratory vaccine (IBR, BVD,
guidelines set forth here are designed to        cow herd.                                       PI3, BRSV)-killed or MLV (see “Ad-
help answer that question but the details                                                        ditional Considerations,” page 99), but
of what products to use and when to            Heifers 6 Weeks Prior to Breeding                 follow label directions regarding MLV
administer them are best decided by the        • Viral respiratory vaccine (IBR, BVD,            usage in nursing calves
producer and veterinarian. Technology            PI3, BRSV) with Campylobacter fetus           • Deworm with an endectocide (exam-
is constantly changing and updating sci-         (vibriosis) and 5-way leptospirosis—            ples: Ivomec®, Dectomax®, Eprinex®,
ence to make today’s vaccines safer and          modified live strongly recommended;             Cydectin®, LongRange®) for internal
more effective than any time in the his-         fetal protection (FP) product is pre-           and external parasites; use a branded
tory of cattle production. However, the          ferred; follow label directions; booster        product—not a generic; drench an-
sheer number and types of vaccines and           at minimum 30 days prior to breeding            thelmintic (white liquid dewormer
dewormers available today can make the         • Seven-way clostridial vaccine (Black-           given by mouth) such as Safeguard®,
correct selection of products challenging.       leg)                                            Synanthic®, or Valbazen® may be used
Every farm has different disease risks and     • Deworm with a branded (not generic)             but a second product will be required
challenges regarding labor and facilities        product; heifer is under increased              for external parasite (flies, lice) control
needed to work the cattle. A veterinarian        nutritional demand because she is still       • 7-way clostridial vaccine (Blackleg);
is equipped with the knowledge and skills        growing herself and trying to repro-            follow label directions regarding the
to determine what will work best in each         duce; young animals do not have the             need for a booster
unique situation.                                immunity to parasites that adult cattle       • Optional: Vaccinate with Mannheimia
                                                 possess, therefore it is important to use       haemolytica toxoid—this vaccine, com-
Cows and Bulls 4-6 Weeks                         effective dewormers                             monly known as a “Pasteurella shot” or
Prior to Breeding                                                                                “Pneumonia shot” is given pre-weaning
• Viral respiratory vaccine (IBR, BVD,         Calves 1-3 Months of Age                          in anticipation of the stress associated
  PI3, BRSV) with Campylobacter fetus          • Identify with tag                               with weaning; in a low-risk situation
  (vibriosis) and 5-way leptospirosis (HB      • Vaccinate with 7-way clostridial (Black-        in which the calves are weaned on the
  optional) Fetal Protection (FP) product        leg) vaccine—although the calves are            farm and no new additions are added to
  preferred. If the cow is pregnant at the       too young to mount a good immune                the group, this vaccine may be delayed
  time of vaccination, use a killed vaccine      response, this dose of vaccine will initi-      until after weaning; consult your veteri-
  product to reduce the risk of accidental       ate (“jump start”) the immune process;          narian and check your marketing plan
  abortion. Certain modified live vac-           do not give Blackleg vaccine at birth.          since many programs (for example:
  cines can be used in pregnant animals,       • Dehorn, castrate—the earlier these              CPH45) specify what vaccines must
  but only if used strictly according to         practices are completed, the better             be administered and when in order to
  label directions.                            • Optional Practices:                             participate.
• Seven-way clostridial vaccine (Black-          » Implant steers at the time of castra-
  leg), necessary if under 2 years of age;          tion (unless you plan to sell calves in    Calves at Weaning
  optional (highly recommended) as the              an organic or natural market)                 Delay working calves until the stress
  cow ages depending on the exposure             » Viral respiratory vaccine-killed,           of weaning is over. It is best to wait until
  risk of the herd                                  MLV (see “Additional Consider-             the calves are eating, drinking, and most
• Deworm—perform at least twice per                 ations,” page 99), or intranasal (intra-   (if not all) have stopped walking and
  year (spring and fall). If only once is           nasal preferred for young animals
Chapter 7—Health and Management Techniques

• Booster 7-way clostridial if required by      the cow is open and the calf is weaned.       ful in all situations. Always discuss concerns
  label direction                             • Killed vaccines provide safe, protec-         with a veterinarian to develop the plan that
• Optional practices:                           tive immunity but must be given twice         will work the best.
  » Implant: Follow label directions,           (usually 2-3 weeks apart) if it is the
     especially when re-implanting. Do          first time a viral respiratory vaccine        Diseases
     not implant females to be used for         is administered. Annual boosters are            Several diseases can be a problem in
     breeding purposes. Do not implant          required after the initial two-shot se-       Kentucky beef herds. By understanding
     if planning to sell on the natural or      quence; twice a year is recommended           the causes of these diseases, producers
     organic markets.                           when using killed products.                   can be better equipped to prevent them.
  » Pasteurella multocida and/or His-         • If heifers have been allowed to stay with
     tophilus somni (formerly known as          the herd bull until weaning, most likely      Anaplasmosis
     Haemophilus somnus) vaccines—              some are pregnant. A prostaglandin               Anaplasmosis is caused by a micro-
     consult with a veterinarian for cur-       injection (for example: Lutalyse®) can        scopic parasite that destroys red blood
     rent recommendations.                      be given to the heifers once they have        cells. Horseflies, mosquitoes, and ticks
                                                been away from the bull a minimum             are the principal blood-sucking insects
Cows after Calves are Weaned                    of 10 days. These injections work best        that spread anaplasmosis. Since the
• Check cows for pregnancy by palpa-            in early pregnancy so do not delay            infection is easily transmitted by the
  tion, ultrasound, or blood test. If open,     administration if needed.                     transfer of infected blood, outbreaks can
  strongly consider culling her.              • Try to minimize the number of injec-          occur after working cattle without proper
• Check for other problems: Eyes, mouth,        tions given at one time as much as            disinfection during procedures such as
  udder, feet and legs, body condition,         possible. Multiple vaccinations cause         dehorning, castrating, ear tagging, and
  disposition.                                  neck soreness. Multiple Gram negative         vaccination without changing the needle.
• Scours vaccine—administer prior to            vaccines may cause cattle to spike a          Disinfect equipment and change needles
  calving. Products vary on when to ad-         fever and go off feed for a short period      between animals to minimize spread of
  minister them during late gestation so        of time.                                      the disease.
  follow label directions carefully.          • Keep good vaccination records. Record            Initial signs of anaplasmosis include
• If leptospirosis is a persistent problem,     date, vaccine name, serial numbers and        fever, weakness, icterus (jaundice), anemia,
  cows may need a booster of 5-way              expiration dates at a minimum.                pale mucous membranes, dehydration,
  leptospirosis vaccine.                      • Utilize fly control and pinkeye vaccine       and constipation. Often no signs are
Additional Considerations:                      beginning in late spring.                     observed and the animal is simply found
                                              • Letters in a vaccine name mean:               dead. Most cases occur in late September,
• If calves cannot be processed pre-            » IBR, BVD, BRSV, and PI3 are dis-            October, and early November in adult
  weaning, then do the steps for “Calves           eases included in a viral respiratory      cattle (usually three years old and up).
  at Weaning” then booster the viral               vaccine.                                      Oxytetracycline is the drug of choice
  respiratory vaccine (and the 7-way            » An “FP” in the vaccine name stands          for treating anaplasmosis. In an outbreak
  clostridial if required on label) in 2-3         for “fetal protection” and means           situation, mass medication of cattle with
  weeks. If castrations and dehorning              protection against fetal infection         a single injection of long acting oxytet-
  were not done earlier while the calf             and abortion due to the BVD virus.         racycline will likely arrest any clinical or
  was on the cow, these practices need          » An “HB” in the vaccine name stands          late prepatent infections. Oral consump-
  to be completed as soon as possible.             for the strain of Leptospira known         tion of chlortetracycline for at least 60
  Tetanus vaccination is strongly recom-           as “Hardjo bovis” that is a common         continuous days at the higher level of
  mended when performing late castra-              cause of reproductive failure in           the approved range 0.5-2 mg per pound
  tion; especially if banding. Consult your        cattle.                                    of body weight during the insect vec-
  veterinarian regarding whether to use         » “HS” stands for “Histophilus somni”         tor season (May-November) has been
  a tetanus toxoid or antitoxin.                   (formerly known as Hemophilus              demonstrated to control active infection.
• Modified live vaccines (MLV) provide             somnus).                                   Currently, no commercial vaccines are
  fast, broad immunity and are excellent        » “L5” stands for the five strains of         available against anaplasmosis although
  stimulators of cell-mediated immunity.           leptospirosis.                             Kentucky is approved by the USDA for
  They are generally preferred in recently      » “V” stands for “vibriosis.”                 sales of the experimental anaplasmosis
  weaned calves and usually required by
                                                In summary, vaccination programs must         vaccine marketed by University Products
  most preconditioned sales. However,
                                                                                              LLC of Baton Rouge, La. The vaccine
  only use modified live vaccines in preg-    be designed around the specific needs of
                                                                                              has provided good protection against
  nant cows and in nursing calves if the      the cattle. Numerous vaccines are available
                                                                                              anaplasmosis throughout the United
  cows were vaccinated with MLV in the last   for other diseases (for example: brucellosis,
                                                                                              States, including Puerto Rico. The vaccine
  12 months (check label for specific re-     anaplasmosis, trichomoniasis, Clostridium
                                              perfringens Type A, foot rot, papilloma or      recommendations include a two-dose
  quirements). If this requirement is not
                                              wart virus) but they may or may not be use-     regimen given four weeks apart with an-
  met, a killed vaccine must be used until
                                                                                              nual revaccination required.

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Chapter 7—Health and Management Techniques

Blackleg                                         condemnation of carcass at slaughter if            used in young calves as these vaccines
   “Blackleg” and “malignant edema” are          tumors are present, and clinical disease/          stimulate immunity in the nose rather
diseases caused by clostridial organisms         death loss.                                        than relying on the immature immune
that live in the ground in a protected spore                                                        system. BRSV can spread quickly in naïve
                                                 Bovine Spongiform Encephalopathy                   cattle (3-10 days) and is found in the nasal
form and enter calves through ingestion,
inhalation or wounds. The bacteria are              Bovine spongiform encephalopathy                and tracheal mucosa in infected calves,
not spread directly from animal to animal        (BSE) is a chronic degenerative disease of         replicating and causing inflammation in
but come from the soil. These organisms          cattle that affects the central nervous sys-       these tissues. Clinical signs of BRSV can
produce toxins (poisons) in the animal’s         tem. It was first diagnosed in the United          take two to four days to develop. BRSV
body that are rapidly fatal. Blackleg usu-       Kingdom in 1987 and is considered rare             infection is associated with high morbid-
ally occurs in cattle six months to two          in North America. BSE is also referred to          ity (60% to 80%), and fatality rates may be
years of age; malignant edema can occur          as “mad cow disease.”                              as high as 20%. BRSV can cause clinical
at an older age.                                    This disease is not contagious and is           disease in older heifers and adult cows,
   The “7-way” or “8-way” clostridial vac-       believed to be caused by a prion. The only         but generally older individuals will have
cine is effective, inexpensive, and eco-         known method that cattle can contract              less severe or subclinical BRSV infection.
nomical. All calves should be vaccinated         BSE is through the consumption of animal
                                                 by-products with infective material such as        Bovine Viral Diarrhea Virus
beginning at two to four months of age,
depending on the product. Follow label           brain, spinal cord, retina, and distal small in-      Bovine viral diarrhea virus (BVD) can
directions carefully regarding what age to       testine. There is neither a treatment nor vac-     cause a variety of clinical conditions,
administer the primary and booster doses         cine to prevent the disease. The incubation        including abortions, birth defects, weak
of the vaccine.                                  period (time from infection to symptoms)           calves at birth, pneumonia, death, and
                                                 is two to eight years. Once clinical signs are     persistent infections. The BVD virus is
Bovine Leukosis Virus                            seen, death usually occurs in two weeks to         frequently diagnosed in Kentucky due
   Bovine leukosis virus (BLV) is a very         six months. Most cases have occurred in            to its immunosuppressive effect that
common occurrence in beef cattle herds.          cattle between three and six years of age,         increases susceptibility to respiratory
The virus is usually transmitted through         usually dairy cattle.                              disease, especially in recently weaned
contact with blood from an infected                 As of 1997, Federal Drug Administra-            stocker calves. There are two forms of
animal. BLV can spread through such pro-         tion (FDA) prohibited the feeding of most          infection; a transient infection (TI) is an
cedures as injections with dirty needles,        mammalian protein to cattle. Several               infection of short duration (usually 10
surgical castration and/or dehorning, tat-       diseases in Kentucky are more common               days to two weeks) during which time
tooing, rectal palpation as well as through      to cause central nervous system (brain)            the calf is very susceptible to contract ad-
biting insect vectors such as horseflies.        signs than BSE. These include listeriosis          ditional diseases because the virus stops
Calves may also be exposed while nurs-           (circling disease), rabies, polioencepha-          the immune system from functioning.
ing an infected dam. BLV is the cause of         lomalacia (thiamine deficiency or high             A persistent infection (PI), on the other
the cancerous blood disease “enzootic            sulfur diet), grass tetany, milk fever, and        hand, is a life-long infection a calf is born
bovine leukemia” (bovine lymphosarcoma           ketosis. You should consult with your              with but does not generally cause prob-
or malignant lymphoma). However, only            veterinarian for an accurate diagnosis if          lems for the infected animal.
approximately 2% of BLV-infected animals         cattle are showing abnormal brain signs,              Persistently infected (PI) calves occur
will go on to develop these cancers affect-      such as staggering, excessive bellowing,           when a pregnant dam with inadequate
ing lymph nodes and white blood cells.           or down (non-ambulatory).                          protection (poorly vaccinated) is infected
Tumors may occur in the spinal canal,                                                               with BVD sometime during 40 to 125
                                                 Bovine Respiratory Disease                         days in gestation. The calf contracts the
uterus, heart, abomasum, kidney and/or
lymph nodes. The most common clinical              See “Pneumonia/shipping fever.”                  virus in utero and is born “persistently” or
signs of cancer in cattle include anorexia,                                                         forever infected. A PI calf may be born un-
                                                 Bovine Respiratory Syncytial Virus                 dersized and have slower growth rates, or
weight loss and fever or sudden death.
                                                    Bovine respiratory syncytial virus              it may appear normal. The most efficient
   Blood testing is the first step to identify
                                                 (BRSV) is a prevalent virus that can cause         transmission source for the BVD virus is
BLV-positive (infected) animals. Test-
                                                 respiratory disease in cattle of all ages          contact with PI cattle. A PI calf continu-
ing should be done in animals over six
                                                 but primarily affects calves in outbreaks.         ously sheds the virus from all secretions
months of age and not around the time
                                                 BRSV is also considered a disease that             during its life. PI bulls can introduce BVD
of calving in cows. Measures to control
                                                 predisposes animals to secondary bacte-            into a herd of cattle through the semen or
BLV include using single-use needles,
                                                 rial infections. Vaccination can reduce            direct contact. There is no treatment to
cleaning and disinfecting equipment
                                                 severity and protect calves and cattle             remove the virus for cattle with persistent
between animals with a disinfectant such
                                                 from disease. BRSV vaccines usually are            BVD infection.
as chlorhexidine, and implementing an
                                                 in combination with other respiratory                 Biosecurity plans should include iso-
integrated pest management program.
                                                 viral vaccines (IBR, PI3, and BVD) and             lation of newly acquired animals for at
Economic losses stem from the inability
                                                 are available in modified-live or killed           least two weeks and testing for the virus,
to sell cattle for export or as bull studs,
                                                 forms. Intranasal BRSV vaccines are often          either by an ear notch (skin) sample or a
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Chapter 7—Health and Management Techniques

serum sample. Limit movement of cattle             be vaccinated by an accredited vet-             calves housed indoors. Cross infection
on and off the farm, especially pregnant           erinarian. Upon vaccinating a calf, the         between animals and humans is possible,
animals, to reduce the chance of exposure.         veterinarian will place an official tattoo      so washing hands is advisable after han-
Vaccination programs routinely are used            and tag in the right ear and record the         dling young scouring calves. There are no
to limit disease from BVD infection, es-           vaccination with the state veterinarian.        medications available in the United States
pecially prebreeding vaccines to promote           Work with your veterinarian to deter-           considered effective against cryptospo-
fetal protection and prevent PI calves.            mine if vaccination is necessary. Herds         ridia. They can survive for long periods
   The commercial viral vaccines available         can be certified brucellosis-free with          in the environment, especially inside
are killed/inactivated or modified-live            annual blood testing.                           barns, so effective cleaning is imperative
virus products. In general, modified-live                                                          to prevent disease.
vaccines should not be used in pregnant            Coccidia
animals unless administered strictly ac-              Coccidia are intracellular protozoan         Foot Rot
cording to the label directions. The killed        parasites that can cause serious economic          Foot rot is an infectious disease charac-
BVD vaccines are safe for use in pregnant          losses due to weight loss, reduced perfor-      terized by sudden lameness and inflam-
cows. When using a killed virus vaccine            mance and possibly death. The coccidian         mation of the tissues between the claws.
for the first time, a booster is required          life cycle is complex. The single-cell oo-      It is caused by injury to the skin between
in two to four weeks after the first vac-          cysts are passed in the feces of infected       the claws, allowing infection with the
cination. Replacement heifers should be            cattle and “sporulate” to form the infective    bacteria Fusobacterium necrophorum and
vaccinated at five to six months of age            stage. The sporulated oocysts are con-          Bacteriodes melaninogenicus. The affected
and booster this in two to four weeks ac-          sumed by a susceptible animal and attack        tissue becomes swollen and painful, and
cording to label directions. Modified live         the lining of the intestine. This develop-      only light weight is placed on the toe. A
vaccines are strongly recommended for              ment cycle in the intestinal tract destroys     characteristic foul odor is easily detected
replacement heifers.                               intestinal cells. The amount of damage          but little pus is observed. Treatment
   Annual revaccination of the breeding            done is directly related to the number of       usually consists of systemic (injectable)
herd is recommended prebreeding to                 oocysts ingested. Outbreaks of bloody           antibiotics or treatment of the interdigital
get maximum fetal protection. All new              diarrhea are associated with the stresses       area with copper sulfate either by wrap-
additions should be screened for PI cattle         of weaning, shipping, overcrowding and          ping the hoof or by footbath. Prevention
with an inexpensive blood test or ear              dietary changes.                                includes good nutrition (especially ad-
notch skin sample since PI animals serve              Coccidiosis is primarily a disease of        equate zinc in the mineral preparation)
as a continuous source of infection. A             confinement. Affected animals may be            and measures to ensure good hoof health
purchased pregnant cow or heifer may               off feed and strain to defecate, resulting in   such as improving drainage to reduce
test negative herself but be carrying a PI         fresh blood in the manure and, in severe        mud and manure buildup.
calf so it is vitally important to test her calf   cases, rectal prolapse. Management tech-
at birth for persistent infection. Consult         niques recommended to reduce exposure           Histophilus somni (formerly
a veterinarian about the appropriate use           to oocysts include decreased stocking           Haemophilus somnus)
of vaccines in your herd as well as testing        rates, minimizing stress, and providing            Histophilus somni is a normal bacteria
procedures to identify and remove PI               clean housing. Feed should be kept off the      found in the upper respiratory and uro-
cattle. Remember, PIs are considered defec-        floor to prevent contamination and wa-          genital tract of cattle but is a source of
tive and there is a legal, moral, and ethical      terers should be cleaned regularly. Use of      problems if it reaches the lungs or blood-
obligation to dispose of these animals with-       the ionophores monensin (Rumensin®) or          stream. Histophilus can cause respiratory
out sending/returning them to commerce.            lasalocid (Bovatec®) or use of decoquinate      (pneumonia), heart, and brain disorders
                                                   (Deccox®) will help prevent coccidiosis.        in feeder calves, and reproductive disor-
Brucellosis                                        Do not allow horses to consume Rumen-           ders in adult cattle. Commercial vaccines
  Brucellosis (Bang’s disease) causes              sin® or Bovatec®. Cattle showing clinical       are available but have very limited success
abortion in cattle. More importantly,              signs of coccidiosis must be treated with       in inducing protection against disease.
brucellosis can cause a disease in humans          drugs such as amprolium (Corid®) or             Thrombotic meningoencephalitis (TME)
called “undulant fever.” Cows with brucel-         sustained-release sulfas to cure clinical       is a rapidly fatal brain disease in cattle due
losis shed large numbers of infectious or-         animals. Consult a veterinarian for treat-      to H. somni.
ganisms at calving. Calves receiving milk          ment and prevention advice.
from infected cows shed live organisms                                                             Infectious Bovine Rhinotracheitis
in the feces. Kentucky is certified brucel-        Cryptosporidia                                    Infectious bovine rhinotracheitis (IBR
losis free along with most of the United             Cryptosporidia are tiny protozoan             or bovine herpes virus-1) is the cause
States except for a few Western states.            parasites that invade the intestinal cells of   of viral respiratory and reproductive
Test and slaughter of infected animals is          the small and large intestine. It is a major    diseases affecting cattle. IBR can cause
required by law. Prevention may include            contributor to calf scours/diarrhea and         respiratory infections, abortion in cows
calfhood vaccination of heifer calves              often becomes deadly in combination             exposed during pregnancy, infertility, and
with RB51 strain vaccine between four              with a virus or bacterial agent. The dis-       eye inflammation (conjunctivitis).
to 10 months of age. Heifer calves must            ease is common in one- to four-week-old
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Chapter 7—Health and Management Techniques

   All forms of IBR can be controlled by        for long periods (potentially 1-5 years) in       Older leptospirosis vaccines have a short
vaccination with products for intranasal        the environment.                                  duration of immunity and require re-
administration or injectable. Modified-            In almost all cases, the MAP bacteria ar-      vaccination every three to four months
live virus vaccines, in combination with        rived on the farm when an infected animal         to maintain adequate herd immunity.
BVD, BRSV and PI3 for injection, are            was purchased and added to the herd. The          Recently, new vaccines against L. hardjo
most effective but can cause abortion in        bacteria can be hiding in replacement heif-       bovis (vaccines with the initials “HB”) have
pregnant animals if label directions are        ers, cows, breeding bulls, recipients used        been shown to protect against that strain
not carefully followed. Calves should be        for embryo transfer, or even in an infected       and provide longer duration of immunity
vaccinated 30 days before weaning and           calf purchased to graft on a cow. It is easy to   (up to one year) than the traditional Lep-
receive a booster dose at weaning or vac-       buy (and sell) infected, young breeding age       to-5 vaccines. The new vaccine does not
cinated at weaning and boostered two            animals with no obvious symptoms even             eliminate carrier animals; treatment with
to four weeks later. Replacement heifers        though they are already incubating the            oxytetracycline is necessary to eliminate
should be vaccinated again at least 30          disease. However, these infected animals          carriers of leptospirosis.
days before breeding. The breeding herd         will shed the MAP organism, in increasing
should receive an annual booster dose,          numbers as the disease progresses, con-           Listeriosis
preferably modified live prebreeding.           taminating the farm environment and in-             Listeriosis (circling disease, silage
                                                creasing the risk of infection spread within      disease) is caused by the bacterium Lis-
Johne’s Disease                                 the herd. MAP-contaminated colostrum              teria monocytogenes that is most often
   Johne’s disease (pronounced yo-knees)        from other herds, especially from dairies,        associated with feeding moldy silage or
is a contagious bacterial infection of the      is another potential source.                      baleage, especially during cool weather.
intestinal tract of ruminants caused by the        No treatment exists for Johne’s disease.       Animals show neurologic disease and
bacterium Mycobacterium avium subsp.            Cattle become shedders of the bacteria            may display head pressing, drooped ear,
paratuberculosis, commonly referred             before they show clinical signs of diarrhea       and/or compulsive circling. The recovery
to as “MAP”. This is a slow, progressive        and weight loss. Cattle can be tested by          rate is best if treatment is administered
disease that begins when calves (not adult      collecting feces and submitting for PCR           early in the course of the disease. Listeria
cattle) are infected with the MAP bacte-        analysis or a blood test can be performed.        may also cause abortion and eye lesions.
ria, most often around the time of birth        A negative result does not guarantee the          Prevention includes discarding moldy
but infection can occur up to 6 months          animal is negative; some animals with in-         feed, especially fermented feeds, and
of age and very rarely after. Johne’s infec-    fection are slow to produce antibodies or         cleaning contaminated areas. Rule out
tion is mainly caused by calves ingesting       shed the organism and are consequently            other diseases that can cause similar signs,
MAP-contaminated feces from nursing             slow to test positive.                            especially rabies.
dirty teats. In beef cattle, this is possible      The key to preventing, controlling,
in high traffic areas (around hay rings,        and eliminating Johne’s disease in a              Neosporosis
feeding areas) when mud and manure are          herd is implementation of appropriate                Neosporosis is caused by a protozoan
splashed on the udder, when calving cows        biosecurity measures including buying             parasite Neospora caninum. The protozoa
in dirty sheds or barns, or when cattle are     only from reputable sources and testing           may affect the developing fetus, but it does
held in close confinement. MAP is also          all new additions in the herd. Consult a          not cause clinical illness in the adult. Once
shed in colostrum and milk of infected          veterinarian to develop a specific plan           infected, the cow is infected for life and
cattle. Once MAP gains entry into a calf,       tailored for the herd.                            there is no effective treatment. Depend-
the organism lives permanently within                                                             ing on when exposure to Neospora occurs
the cells of the small and large intestine      Leptospirosis                                     during gestation, infection may result in
where it multiplies and causes the intes-          Leptospirosis (often referred to as            fetal death, abortion, stillbirth, or birth of
tinal lining to slowly thicken. With time,      “Lepto”) is a bacterial disease that causes       weak calves. In future pregnancies, nor-
the thickened intestine loses the ability to    abortions, stillbirths, and birth of weak         mal calves may be born already infected
absorb nutrients, resulting in watery diar-     calves. Leptospira hardjo (L. borgpetersenii      with the organism and can pass it on to
rhea. There is no blood or mucus in the         serovar hardjo) and pomona (L. interro-           their offspring. The disease is primarily a
feces and no straining. The clinical signs of   gans serovar pomona) are the two strains          problem in dairy cattle but is increasingly
diarrhea and extreme weight loss in spite       of primary concern for Kentucky cattle.           found in beef cattle. Abortion epidemics
of having a good appetite, do not show up       The infection localizes in the kidneys and        may occur if feed is contaminated with
until 2-5 years of age or even older. There     is shed in the urine to infect other cattle       the organism.
is no treatment available and the animal        or humans. Prevention of leptospirosis is            The dog and the coyote have been iden-
eventually dies due to starvation and           a good reason to keep cattle out of stag-         tified as the definitive hosts and is where
dehydration. The MAP organism begins            nant ponds.                                       the parasite produces the infective eggs
to be “shed” in the feces years before diar-       All breeding-age female cattle should          (oocysts). Cattle are exposed to Neospora
rhea starts and continues until the animal’s    be vaccinated against the five strains of         caninum with accidental ingestion of feed
death. Map bacteria are very hardy due to       leptospirosis. Annual revaccination is            or water contaminated with dog or coyote
a protective cell wall that allows survival     highly recommended, especially when               feces containing the oocysts. Cows can
                                                cattle are allowed access to farm ponds.          be blood tested to determine if they have
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Chapter 7—Health and Management Techniques

been infected. Diagnosis of the infection in     if the eye is improving or deteriorating       (IBR), and parainfluenza (PI3). Bacte-
affected calves is based on heart and brain      when covered. If the case of pinkeye is        rial agents are ultimately responsible for
abnormalities in the calf or aborted fetus,      very advanced, a veterinarian may suture       the severe lung damage. Bacteria take
abnormalities in the placenta and positive       the eyelids together or use a third eyelid     advantage of stress and viral infection
blood tests. A vaccine was available but has     flap to stabilize the cornea. Do not rely      to overcome the immune defenses and
been withdrawn from the market.                  on sprays alone since they remain in the       cause pneumonia. Mannheimia (formerly
                                                 eye just a few minutes before tears wash       Pasteurella) haemolytica is the bacterium
Parainfluenza Type 3                             them away. To be effective, sprays must        that often causes “shipping fever pneu-
   Parainfluenza type 3 (PI-3) primar-           be applied 3-4 times daily. Vaccination        monia,” especially in stocker and feedlot
ily causes mild respiratory problems in          alone will not prevent disease but may         cattle. These bacteria can cause severe
cattle. It is considered to be a secondary       allow faster response to treatment. An         pneumonia and result in quick death if
factor in shipping fever outbreaks. Ef-          overall good level of nutrition, adequate      the animal is not treated with effective
fective vaccines are available, including        vitamin and trace mineral intake, a com-       antibiotics early in the course of disease.
intranasal vaccines or modified-live             prehensive vaccination program, and            Pasteurella multocida, Histophilus somni,
and/or killed vaccines for injection. PI-3       parasite (fly) control are all exception-      and Mycoplasma bovis are other bacterial
vaccines are usually given in combina-           ally important in improving an animal’s        species that can contribute to pneumonia
tion with IBR, BVD, and BRSV.                    ability to fight off any disease process. To   (Table 7-3).
                                                 reduce as many of the pinkeye risk fac-           Successful treatment of BRD involves
Pinkeye                                          tors as possible, prevent corneal damage       early recognition of sick animals, appro-
   Pinkeye (infectious bovine keratocon-         from sun by providing shade, control face      priate treatment, follow-up, and prompt
junctivitis) in cattle is characterized by       flies, clip pastures to prevent mechanical     retreatment of relapses. Clinical signs
inflammation and watering of the eye,            injury from grass and plants, and provide      include depression (Table 7-4), decreased
painful sensitivity to light, and varying        an abundant clean water source in order        appetite (Table 7-5), abnormal breathing
degrees of corneal damage. Research in           to keep calves hydrated, allowing the          (Table 7-6), and fever on examination
Kentucky indicates a definite decrease in        eye to stay clean and moist. Recent eye        (Table 7-7). Coughing is not always pres-
weaning weight of calves with pinkeye.           cultures have indicated that Moraxella         ent early in pneumonia. It is important to
This decreased performance, coupled              bovoculi also contributes to pinkeye, es-      watch cattle at feeding time. Sick calves
with a decrease in selling price of affected     pecially cases in the winter months. Some      may walk to the bunk but not eat.
calves, can mean significant losses for          veterinarians have autogenous vaccines            Antibiotics and other therapeutic
Kentucky beef producers.                         prepared from pinkeye cases cultured on        agents should be selected on the basis
   Pinkeye is caused by the bacteria Mo-         the farm to stimulate immunity against         of symptoms shown and with a protocol
raxella bovis. These bacteria are covered        both M. bovis and bovoculi.                    developed with a veterinarian. Often bac-
with hair-like structures used to attach            For further information, see ID-135:        terial organisms become resistant to an
to the cornea or clear portion of the eye.       Infectious Bovine Keratoconjunctivitis         antibiotic that has worked well in the past
Once attached, it releases a toxin that kills    (‘Pinkeye’) in Cattle (http://www2.ca.uky.     and a new antibiotic must be selected.
cells on the surface of the cornea. Early        edu/agc/pubs/id/id135/id135.pdf ).             Mass treatment of all calves (metaphy-
detection and prompt effective treat-                                                           laxis) should be considered if sickness is
ment are essential to reducing spread and        Pneumonia/Shipping Fever/Bovine                expected in a group of high-risk calves
limiting damage to eye. The earliest signs       Respiratory Disease Complex                    or if increasing rapidly. A hospital pen is
include a large amount of watery tears             Pneumonia/shipping fever/bovine              an option so sick animals can be closely
that often flow down the face, excessive         respiratory disease (BRD) is caused by a       observed and easily treated but must be
blinking, squinting, and sensitivity to          complex interaction of bacterial and viral     cleaned and sanitized regularly.
light. In 1 to 2 days, the cornea appears        organisms along with stress in an animal,         Prevention includes reducing stress
white and a small ulcer or “pit” develops        leading to infection and inflammation of       and exposure while promoting resistance
towards the center of the eye. Some cases        the lungs. Clinical signs include depres-      to infection. Preconditioning is one suc-
will resolve while others progress to deep       sion, fever, off-feed, an increase in the      cessful approach. This management and
ulceration and corneal rupture.                  rate and depth of respiration, cough, nasal    marketing program significantly reduces
   Treatment with a long acting antibiotic       discharge, and open-mouth breathing.           illness and death due to BRD. The Ken-
along with topical fly repellant is the best     BRD is associated with the stress reaction     tucky Certified Preconditioned for Health
course of action to reduce the spread            to changes in diet, a new environment,         CPH-45 program ensures that the calves
of pinkeye in the herd. Active cases of          weather, water, dehorning, castration,         have been vaccinated, weaned a mini-
pinkeye with excessive tearing attract flies     weaning, handling, confinement, hauling,       mum of 45 days and have learned to eat
that spread the bacteria quickly. Work           and mixing with new groups of calves.          from a feed bunk and drink water from a
with a veterinarian to determine the best          Several viruses are major contribu-          trough. The calves must be offered a free
antibiotic for the situation. Isolation of the   tors to BRD. They are highly contagious        choice mineral with minimum specifics
affected animals will also help limit the        and include bovine respiratory syncytial       for copper, selenium, zinc, manganese,
spread. A patch can be used to protect an        virus (BRSV), bovine viral diarrhea virus      and salt content. The program includes
affected eye however it is difficult to see      (BVD), infectious bovine rhinotracheitis       required vaccinations (IBR, PI-3, BVD,
                                                                     102
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