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Forward looking statements: This document has been prepared for informa- terminology. These forward-looking statements are not tional purposes only. This document contains guarantees of future performance and by their nature summary information about Brain Scientific Inc. (“Brain involve known and unknown risks and uncertainties that Scientific”), does not purport to be complete, and no may cause actual opportunities, prospects, performance representations or warranties about such information are and results to vary from those presented in this document, made by Brain Scientific or its representatives. and those variances may be material. In evaluating such statements, prospective investors should carefully This document does not constitute an offer to sell or a consider the various risks and uncertainties identified solicitation of an offer to purchase any securities of Brain in Brain Scientific’s public filings with the Securities and Scientific. Any such offer will be made only pursuant to Exchange Commission, such as market risk, liquidity risk, an effective registration statement or an exemption from competitive risk, regulatory risk and other commonly registration. recognized forms of risk relating to Brain Scientific and its securities. In light of these risks, uncertainties and This document contains forward-looking statements assumptions, the forward-looking events discussed in relating to future events or the future financial this document might not occur. Brain Scientific is not performance and operations of Brain Scientific. Forward- obligated to publicly update or revise any forward-looking looking statements, which involve assumptions and statements, whether as a result of new information, future describe Brain Scientific’s intent, belief or current events or otherwise. expectations about its business opportunities, prospects, performance and results, are generally identifiable by No independent party has audited the forecasts, if any, set use of the words “may,” “could,” “should,” “will,” “would,” forth herein, nor has any independent party undertaken “expect,” “anticipate,” “plan,” “potential,” “estimate,” to confirm that any hypothetical performance or other “believe,” “intend,” “project,” “forecast,” the negative of performance that may be set forth herein adheres to the such words and other variations on such words or similar assumptions or conditions specified herein. 2
Who we are Technology Brain Scientific is a commercial- Development of technologies including: stage company offering products and solutions related to the brain Phase I Phase II Phase III including neurology, AI and 2018–2019 2020 2021–22 machine learning. Founded in 2015 as an extension of Brain Rx, a pre-Alzheimer diagnostic company. Portable, clinical-grade, Secure, cloud-based, Artificial Intelligence easy-to-use neurological highly scalable infrastruc- assisted diagnostic analy- diagnostic devices. ture to transmit sis to increase neurologist Headquartered in New York. patient data between efficiency, consistency neurologists and patients. and accuracy. Went public in September, 2018 (BRSF) Intellectual Property: 3 patents in Us, China, and Europe 3
NeuroCaptm • NeuroCapTM, a PATENTED disposable EEG headset with 22 pre-gelled electrodes following the international 10–20 system. • Easy Setup. • FDA cleared in 2018. 4
NeuroEEGtm • NeuroEEGTM, a PATENTED portable, wireless, 16-channel amplifier. • Fits in the palm of your hand. • Can easily be deployed across broad spectrum of patient settings. • User-friendly intuitive NeuroEEGTM Software™ requires minimal training. • FDA cleared in 2018. 5
EEG INDUSTRY LIMITATIONS Current EEG procedure is slow, expensive and cumbersome • Specialized EEG technologists are needed • Bulky equipment • Specialized neurologists are needed to read the EEG data Seizure Treat while EEG tech Neurologist suspicion waiting arrives interprets for EEG EEG result from 1 to 24 hours 1 2 3 4 5 6 7 from 2 to 48 hours EEG order Record EEG Treatment based on EEG results 6
Brain Scientific EEG Solution Setup Recording Analysis Proprietary disposable Pocket-sized EEG Cloud EEG Reading. headband can be set up with all the functionality Raw EEG data is in- by anyone within 5 min. of the conventional EEG. stantly transferred to a server for access and interpretation by EEG trained neurologist for formal diagnosis. 7
NeuroCap™ Benefits • Fixed Pre-Gelled Electrodes allow any clinical personnel (nurse, medical assistants) to apply EEG in 5 minutes or less. • Disposable Headset eliminates patient’s exposure to infection and the need to sanitize elec- trodes after each use. • 3rd party compatibility allows NeuroCapTM to work with conven- tional EEG amplifiers in use. 8
NeuroEEG™ Benefits • Low-cost, Portable and Wireless amplifier provides the same quality of signal as conventional EEG devices. • Assists in automated seizure detection with the ability for EEG data to be reviewed in real-time and post hoc. • Cost savings vs. conventional amplifiers. 9
Customer Benefits ✓ Reduced hospital operational and administrative costs by substituting technology for technicians. ✓ Expansion of EEG coverage to rural areas enabling hospitals to provide 24/7 monitoring during late nights and weekends. ✓ Enhanced patient retention, eliminating outpatient referral, as hospitals implement low-cost, easy to use EEG monitoring on-site. ✓ Remote data review and evaluation as neurologists access patient data through 3rd party software integration with Persyst or Citrix. ✓ Reduction of hospital-acquired infections. 10
Target Markets • Urban Emergency Depart- ments and Intensive Care Units Tertiary Care • Community / Rural Hospitals • Neurologist Practice Ambulatory Care • Primary Care / Internal Medicine • Pain Management Clinics Independent Diagnostic • Sleep Labs Testing Facilities (IDTF) • Nursing Homes • Mobile Clinics 11
Urban ED and ICU Millions of patients in US hospitals can have seizures and will benefit from instant EEG. Emergence Department ICU 130,000,000 ED visits per year in the US 10,000,000 AMS 5,600,000 ICU (Altered Mental Status) patients per year ~ 5,000,000 4,000,000 1,000,000 patients will subject subject to seizure1 to seizure1 be candidates for EEG tests NCSE Non-Convulsive Status Epilepticus NCSE >>65,000 NCSE patients currently diagnosed in the US per year. With EEGs being more accessible, this number is expected to rise significantly. 1. Include head trauma patients (2.1 Mn ED visits), stroke patients (800,000 ED visits), and epilepsy related ED visits (1Mn), brain tumor or infection 12
Community / Rural Hospitals and Neurologist Practice Community / Rural Hospitals Neurologist Practice Only 254 of 6210 US hospitals are 16,000 Neurologists in US, Level 4 Epilepsy centers approximately 3000 are Epileptologists, that have 24/7 EEG coverage less than 1000 are pediatric neurologists Very few non Level 4 Epilepsy centers have All are incentivized in some way to increase 24/7 EEG tech coverage revenue and expand services, including EEG Opportunity to extend much needed EEG Brain Scientific provides easy way to in- services to over 5900 hospitals with lower crease billing and expand services at both cost amplifier and disposable EEG cap the hospital and within practices www.naec-epilepsy.org/about-epilepsy-centers/find-an-epilepsy-center/all-epilepsy-center-locations 13
GO-TO Market Strategy Combine EEG Partner with Bundle dispos- diagnostic industry leaders Leverage Integrate our able EEG + hardware in EEG manu- relationships EEG solution respiratory with PainQx facturing and with medical with existing equipment pain predictive distributors to distributors telemedicine to service the algorithms to service national and GPOs platforms growing sleep service the and global EEG market pain manage- market ment market 14
Competitive Landscape Disposable Cap + + – + Portable + + + + Integrated Software + + + + Compatibility with other EEG products + + – – Teleneurology Enablement + – – + Reduced Depen- dence on EEG techs + + + + AI assisted analysis + – – – 15
Product Roadmap Developing product line extensions to address new, growing markets: Pediatric and Long-Term Monitoring. Long-Term Artificial Pediatric EEG Routine EEG Monitoring Intelligence Caps Pediatric Adults New products for New products for New products for New products for Routine market: Pediatric market: LTM market (24+ hours): AI market: NeuroCap-8 NeuroCap-8 Pediatric NeuroCap-8-Adult Brain E-Tattoo (with 8 channels) NeuroCap-19-Adult Brain AI: Neural Network enabled predictive NeuroCap-8 Pediatric capabilities for brain NeuroEEG Amplifier health / disease (24 channels) progression 16
BRAIN E-TATTOO: SUBCUTANEOUS IMPLANTABLE EEG ELECTRODE • 4 channels • Designed for long-term monitoring to detect epileptic seizures • Minimally invasive implantation • Better EEG signal quality and sensitivity 17
Building Brain AI database of biomarkers • Creating a database of normal and abnor- mal brains for detecting seizures and de- mentia • Developing algorithms to detect epilepsy, memory dementia, pre Alzheimer’s diag- nostics • AI and Machine learning process to see ab- normal activity on a big database Working with current databases October, 2019: 1st stage of development a machine learning algorithm for epilepsy (600 patients) 18
Thank you! info@memorymd.com www.brainscientific.com
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