COMBINED ADVANCED BOTULINUM TOXIN AND DERMAL FILLERS COURSE - Practical Guide - Acquisition ...
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Advanced : PRACTICAL GUIDE DISCLAIMER This practical guide and accompanying training course comprises theoretical, educational and clinical experience of the trainers. It is based on current medical literature and available guidelines and should be used in conjunction with the online E- learning modules, online guidelines and E- learning videos supplied to you. Certification of the course is dependent on attendance and all qualified professionals must retain the responsibility to practice within their competencies and skill set. No trainers on this course take responsibility for the delegate’s subsequent action as a result of attending this course. Anatomy references Endoscopic Plastic Surgery, Bostwick, Eaves & Nahai, 1st Edition Clemente Anatomy- A Regional Atlas of the Human Body, 4th Edition Acquisition Aesthetics’ medical illustrator
Advanced : PRACTICAL GUIDE ANATOMICAL CONSIDERATIONS Progressing towards more advanced applications of Botulinum toxin and dermal fillers, practitioners need to be aware of the relevant underlying anatomical structures including layers in the face, muscles, nerves and blood vessels. FACIAL MUSLCES Aesthetic practitioners should have a good understanding of facial muscles, both those to target with treatment and those to avoid to prevent complications.
Advanced : PRACTICAL GUIDE BLOOD VESSELS Injecting major blood vessels can lead to haematoma formation but also introduces the risk of embolisation, vessel occlusion, ischaemia and infarction of distant tissues. The vascular anatomy of the face largely dictates the ‘danger zones’ of treatment, especially with regards to the angular artery, supratrochlear artery and infraorbital artery. Ø Angular artery: embolic occlusion of this vessel can result in ischaemic necrosis of the cheek and nasal septum and even blindness Ø Supratrochelar artery: occlusion can result in blindness and ophthalmoplegia Ø Infraorbital artery: occlusion of this vessel can result in immediate and permanent blindness
Advanced : PRACTICAL GUIDE NERVES OF THE FACE Nerve Nerve 1 Supraorbital (medial branch) n. 8 Buccal branch of facial n. 2 Supraorbital (lateral branch) n. 9 Mental n. 3 Supratrochlear n. 10 Zygomaticotemporal n. 4 Infratrochlear n. 11 Auriculotemporal n. 5 Lacrimal n. 12 Zygomaticofacial n. 6 External nasal n. 13 Great auricular n. 7 Infraorbital n. 14 Supraorbitaln.n.
Advanced : PRACTICAL GUIDE RECONSTITUTION: HOW TO: STEP BY STEP GUIDE WHAT YOU WILL REQUIRE: FMS 32G Fine Micro Syringes 21G green 0.3ml Azzulure needle 0.63ml syringe Kapoff or haemostat clip STEPS TO RECONSTITUTE BOTULINUM TOXIN (AZZULURE): 1. Remove Azzulure vial from pack and clean top of vial with a cliniprep or chloroprep. Cleaning the top of the vial is optional and some practitioners choose not do this with an alcohol based wipe. 2. Release vacuum of Azzulure vial with green needle. 3. Draw up 0.7ml of bacteriostatic saline into the Azzulure green syringe and decant the saline into the Azzulure vial. 0.7ml will allow for some inevitable loss in your syringe. 4. Swirl the saline around gently but thoroughly- do not shake and do not tip the vial upside down. Discard the green needle and Azzulure syringe. 5. Remove cap from Azzulure vial using Kapoff or clip. 6. Draw up required amounts into 3 FMS needles: i) 50 units for glabella, ii) 40 units for crows feet and iii) 20 units for frontalis. 3 separate FMS syringes should be used. 7. Inject as required.
Advanced : PRACTICAL GUIDE BOTULINUM TOXIN FOUNDATION REFRESHER The key target areas for Botulinum toxin are dictated by ‘activity lines’ produced by facial expression. Treatment zones covered in the foundation course include: Ø Glabella (frown) lines Ø Horizontal forehead (frontalis) lines Ø Crow’s feet (lateral canthal lines This diagram represents a standard treatment regimen of upper face wrinkles with Botulinum toxin using a 125 Speywood units of Azzalure® diluted into 0.63ml Normal Saline as per manufacturer guidance.
Advanced : PRACTICAL GUIDE ADVANCED TECHNIQUES Advanced applications of Botulinum toxin include a range of lower face treatments, combination treatments and the management of complications. As practitioners become more experienced they should move away from generic standardised regimens and assess the needs of each client individually to develop personalized treatment plans. NASALIS TREATMENT – ‘BUNNY LINES’ Ø Wrinkles on the dorsolateral aspect of the nose which develop due to the activity of nasalis muscle. Ø Exaggerated in laughing / squinting. Ø Can develop through compensatory over-activity of nasalis secondary to treatment of glabella complex. Ø Treat with 5 Speywood units in the body of each nasalis muscle, injected superficially.
Advanced : PRACTICAL GUIDE EYEBROW LIFT Ø Botulinum toxin can be used to perform a chemical eyebrow lift and appropriate client assessment is essential before treatment. Ø 2.5- 5 Speywood units are injected superficially, at least 1.5cm above the lateral aspect of the supraorbital rim. This may be just below or within the eyebrow itself. Ø If undertaking a full eyebrow reshape, the treatment can be expanded with further injections at the peak of the eyebrow with 2.5 further Speywood units. Ø In order to complete the treatment and offer a full eyebrow lift and reshape, one should concomitantly treat the Glabella with a full 50 Speywood units and the lateral canthal lines with 20 Speywood units. Ø The treatment of the eyebrow lift and re-shape targets the upper outer fibres of the orbicularis oculi muscle- a depressor muscle.
Advanced : PRACTICAL GUIDE OBICULARIS ORIS TREATMENT - ‘SMOKER’S LINES’ Ø These perioral lines are created by the activity of orbicularis oris that encircles the mouth. Ø Early lines can be treated with a combination of toxin and filler injections to give excellent results. Ø Small doses (2.5 Speywood units) can be injected above the upper lip (>4mm superior to the vermillion border). Ø Injections should be perpendicular to the skin, approximately 2mm depth. Ø Note – deeper/ static smoker’s lines may require dermal filler treatment (combined with Botulinum toxin or alternatively). Before After
Advanced : PRACTICAL GUIDE MENTALIS TREATMENT – CHIN DIMPLING Ø Contraction of the mentalis muscle in the chin can create this dimpling/ pebbling effect. Ø Exaggerated by pouting / drawing lower lip in and up, allowing you to hold the contracted muscle belly Ø Inject
Advanced : PRACTICAL GUIDE LEVATOR LABII SUPERIORIS TREATMENT FOR EXCESSIVE GINGIVAL DISPLAY OR ‘GUMMY SMILE’ Ø In full smile, the aesthetic ideal is considered 90% incisor display and minimal gingival display Ø A gummy smile (excessive gingival display) can occur through over activity of levator labii superioris and zygomaticus minor. Ø Botulinum toxin can be injected to relax these elevators and soften a gummy smile Ø Small doses (
Advanced : PRACTICAL GUIDE MASSETERIC HYPERTROPHY Botulinum toxin can be used to reduce the strength and bulk of the masseter (chewing) muscles to reduce the width of the jaws. This treatment appeals to clients with overly square jawlines who wish to achieve a more feminine look. It can also be used to treat patients who suffer with bruxism. 60 Speywood units are injected into the superficial and deep fibres of the masseter, with 20 Speywood units at each of the 3 sites represented below. Before After
Advanced : PRACTICAL GUIDE PLATYSMA TREATMENT – ‘NEFERTITI NECK LIFT’ Ø This technique relaxes the muscular bands of platysma which can exaggerate the jowl effect and create the ‘turkey neck’ appearance. Ø Botulinum toxin enhances jawline definition, softens jowls and creates a ‘lift’ in the lower face. Ø Product is injected along the jawline and along the bands of the platysma muscle across 20- 25 marked sites. Ø A double dilution technique is adopted, where 1.25mls is used to dilute 1 vial of Azzalure® and 5 Speywood units are injected into each site. Ø The epidermis and dermis are gently elevated during the injection, along the band. Ø These bands can be identified by asking the patient to draw the corners of the mouth downwards, or say the vowel ‘E’, allowing you to isolate the muscle and inject. Before After
Advanced : PRACTICAL GUIDE HYPERHIDROSIS Ø Hyperhidrosis (excessive sweating) of the arm pits (axillae) and palms of the hands or soles of the feet can be treated with Botulinum toxin. Ø Botulinum toxin temporarily blocks cholinergic stimulation of apocrine sweat glands, giving up to 6 months’ relief from excessive sweating. Ø Can only be used to treat defined areas (not useful in generalised hyperhidrosis). Ø Note – treatment of palmar hyperhidrosis can be very painful and therefore anaesthetic should be considered. The client must be given specific instructions with regards to aftercare and caution whilst the anaesthetic is wearing off. Ø A double dilution technique is used of 1.25ml saline to a vial of Azzalure® Ø In the axillae, mark out a grid of 12 injection sites across the main sweat producing zone with 5 Speywood units injected at each site (total 62 Speywood units per axilla)
Advanced : PRACTICAL GUIDE DEPRESSOR ANGULI ORIS TREATMENT – DOWN TURNED CORNERS OF THE MOUTH Ø Low doses of Botulinum toxin can be injected into depressor anguli oris (DAO) muscles to eliminate the downwards pull on the oral commissures and lift the down turned corners of the mouth. Ø The muscle is identified by asking the client to draw their lower lip downwards. Ø Inject 5 Speywood units perpendicularly to the skin into the belly of these muscles which should lie approximately midway between the oral commissure and the mandible. Before After
Advanced : PRACTICAL GUIDE DERMAL FILLERS FOUNDATION REFRESHER Dermal fillers are injectable materials used to reduce wrinkles and treat deficits in facial volume. Products work to mitigate the signs of ageing and improve facial contouring, ultimately providing long-term facial aesthetic enhancement. Hyaluronic acid (HA) fillers are the most widely used type of dermal filler. These products are most commonly used for the following purposes: Ø Reducing wrinkles Ø Correcting deep nasolabial folds and marionette lines Ø Correcting age-related volume loss in the cheeks and chin, for example Ø Firming the skin Ø Enhancing facial contours Ø Lip definition GALDERMA RESTYLANE RANGE: TWO TECHNOLOGIES
Advanced : PRACTICAL GUIDE Treatment areas for each product in the OBT range. As this product is less structured than the NASHA range, one can afford to place it under a less good skin quality. It is best for dynamic areas such as the Nasolabial folds. Treatment areas for each product in the NASHA range. A firm, good quality skin envelope is generally required for this product range. 19
Advanced : PRACTICAL GUIDE The Restylane® Portfolio 20
Advanced : PRACTICAL GUIDE 21
Advanced : PRACTICAL GUIDE TEOXANE PRODUCT RANGE 22
Advanced : PRACTICAL GUIDE INJECTION TECHNIQUES- REFRESHER Techniques of delivery vary depending on the indication, site, product and experience and preference of the injector. Please refer to Foundation training materials for more detail on these basic techniques including the treatment of nasolabial folds and marionette lines. LINEAR THREADING The product is deposited in a linear fashion as the needle is steadily withdrawn. This is one of the most commonly used method. SERIAL PUNCTURE Deeper deposition of droplets of product with serial injections along a wrinkle. This technique may be used to correct deep glabella creases. FANNING The product is deposited immediately deep to the dermis through a series of small linear threads by passing advancing and withdrawing the needle back and forth to treat the area of concern. The product is deposited as the needle is withdrawn. CROSS- HATCHING The cross-hatch technique describes injecting multiple perpendicular threads of product to create a weaving effect. This can correct heavy volume loss and can be used in areas such as deep marionette lines. DEPOT/BOLUS A certain volume of product is deposited at the desired depth in a single bolus. This technique can be used for adding volume to the lips and cheeks, for example. Inject slowly to avoid discomfort caused by rapid expansion of the tissues.
Advanced : PRACTICAL GUIDE ADVANCED TECHNIQUES LIP AUGMENTATION: Practitioners should aim to achieve a natural fullness, a well-defined vermilion border and cupid’s bow, good projection, smooth surface appearance and an aesthetic balance between the upper and lower lip (ideally 1:1.6). Restylane Kysse is the product of choice for lip augmentation.
Advanced : PRACTICAL GUIDE CHEEK AUGMENTATION With advancing age, the effects of volume loss and gravitational descent lead to a squaring effect of the face often with loss of volume in the cheeks. Dermal fillers can be used to restore volume and return the cheeks to a more youthful high position. The initial injections are deep and product is deposited in boluses (0.1-0.4mls) just superficial to the periosteum to create an anchoring effect. A high viscosity product is therefore required, such as Restylane Lyft, Volyme or Defyne To guide accurate product placement, the following technique can be applied but it varies between practitioners and clients and there are other landmarks that can be used: Draw 3 individual lines to form a triangle: Ø From the upper border of the tragus to the oral commissure Ø From the oral commissure to the lateral canthus Ø From the lateral canthus to the upper border of the tragus Ø Within this triangle draw an oval and then horizontally divide the oval into two hemispheres – upper and lower. Ø Split the upper hemisphere into 3 vertical sections- the three sections represent the 3 main injection sites for cheek augmentation. Ø From medial to lateral, these are the anteromedial cheek, zygomatic eminence and zygomatic arch. Ø Additional injections can be given into the lower hemisphere segments and towards the hairline to the upper outer aspect of the treatment zone.
Advanced : PRACTICAL GUIDE JAW CONTOURING The product of choice for this area is Restylane Lyft. The process of ageing can lead to sagging of the lower face including the jawline and chin. Dermal fillers can be used to return definition to this area to achieve a more youthful appearance using both the needle and cannula techniques. Unlike conventional needles which are rigid and have a sharp tip, the microcannula is flexible and has a blunt tip (therefore requiring an introducer to penetrate through the dermis and epidermis). Rather than piercing through the tissues, the cannula opens up its path between the anatomic structures of the skin. As a result, using Microcannula for filler injection offers several advantages over conventional needles, such as: Ø Less bruising Ø Less swelling Ø Significant reduction in pain and discomfort Ø Minimized downtime following the procedure Ø Less risk of trauma and damage to the tissues NEEDLE VS. MICROCANNULA Image taken from www.dermasculpt.net
Advanced : PRACTICAL GUIDE JAW CONTOURING TECHNIQUE Ø A deep bolus can be injected on the outer aspect of the angle of the mandible to provide anchoring support. Ø Serial boluses can then be injected along the length of the jawline and massaged to create smooth volume enhancement using a microcannula or needle technique. Be aware of the facial artery in this region as is ascends to cross the border of the mandible Ø Alternatively, the length of the jawline can be injected using the microcannula and deposition of product in a linear retrograde manner. Ø A deep bolus is often desirable in the pre-jowl sulcus to reduce the jowling effect and support the chin. Be aware of the emergence of the mental nerve in this region Before After
Advanced : PRACTICAL GUIDE TEMPORAL HOLLOWS Hollow and sunken temples can commonly develop as we get older. With advancing age, there is a general loss of volume and descent of tissues from the mid-face making the temple area appear concave and the supporting tissues around the eyes looking pointed and harsh. Dermal filler can be injected to restore youthful smooth contours to the temple area, replacing volume that has been lost. Products that can be used in this area include Restylane Volyme. Ø When treating this area be aware of important vasculature: frontal branch of the superficial temporal artery. Move any obvious veins out of the way by mobilising the skin, to avoid bruising. Ø Injections are placed deeply, vertically down to bone at 90o to the skin. Ø Insertion points are located 1cm above the supraorbital rim, superiorly along the temporal fusion line and 1cm posteriorly, following the arch of the supraorbital rim. Ø Inject slowly as the product used is viscous. The product will spread between the temporalis and temporal fascia and will not pass beyond the fusion lines and thus, generally, they do not need to be blocked. Ø Provide a blocking and supporting flat index finger superiorly to prevent product spread. Ø Typical injection volumes range from 0.4ml- 0.8ml depending on the size of the defect, quality of overlying skin and serial assessments.
Advanced : PRACTICAL GUIDE SUGGESTED INJECTION ZONE FOR SOFT TISSUE FILLERS IN THE TEMPLE Carruthers, Jean; Humphrey, Shannon; Beleznay, Katie et al. Dermatologic Surgery: May 2017 - Volume 43 - Issue 5 - p 756–757
Advanced : PRACTICAL GUIDE PERI-ORAL LINES Peri- oral lines can be treated with horizontal retrograde linear threading, traversing multiple lines with each line of product and avoiding over-treatment. This technique also minimises the number of injections required, reducing client discomfort. Ø Identify the target areas by asking the patient to purse their lips. Ø Select a low viscosity product, for example Restylane Fynesse, Refyne or Restylane Kysse. Ø Deposit the product with a series of horizontal retrograde linear threads (approx. 0.05ml). Ø paralleling the vermillion border Ø Do not breach the vermillion border (remain >4mm above). Ø Stubborn lines can be treated with a vertical linear thread. Ø Massage to achieve even distribution. Before After
Advanced : PRACTICAL GUIDE HAND REJUVENATION Loss of elastin and atrophy of subcutaneous tissue leads to exposure of subcutaneous structures and an aged appearance of the hands. Volume restoration can be achieved through the use of dermal fillers. The 3 key techniques in hand rejuvenation are: Ø Tenting (single bolus deposition) Ø Serial puncture (multiple deposition points along a line) Ø Micro-droplets (tiny amounts of product across a broad area) Treatment should be limited to the flat dorsal surface of the hand at least 2cm within the boundaries created by the metacarpophalangeal joints and the wrist joint. Acquisition Aesthetics advocates the use of the cannula technique in this area to minimise client discomfort and increase treatment area accessed with one insertion point.
Advanced : PRACTICAL GUIDE COMPLICATIONS OF TREATMENT WITH DERMAL FILLERS Please refer to the guidelines provided for you online in your members’ login area through the Acquisition Aesthetics website. These include, but not limited to, guidelines on the following complications: Ø Tyndall effect Ø Vascular occlusion and use of Hyalase Ø Bruising Ø Infection Ø Granuloma formation Ø Delayed onset nodule formation (DONs) Ø Anaphylaxis and hypersensitivity reactions Ø Tissue necrosis Complications can be broadly categorised into early and late time frames. EARLY LATE • Local injection site reactions: • Granulomas I. Bruising • Migration of product II. Swelling • Scarring III. Redness • Asymmetry IV. Pain • Nodules V. Itching VI. Infections • Allergic reaction/ hypersensitivity • Lumps caused by misdistribution • Tissue Necrosis • Vascular occlusion leading to blanching, skin necrosis and/ or blindness • Asymmetry
Advanced : PRACTICAL GUIDE BRUISING Ø Immediately stop injecting and apply a cold compress with some pressure. Ø Monitor the bruise and tell the patient it may become worse over 12 hours. Ø Supply the client with Arnicare cream. TYNDALL EFFECT Ø The Tyndall effect is used to describe the bluish hue that is visible within the skin caused by too superficial placement of hyaluronic acid (HA) filler. Ø It can be avoided by ensuring that the colour of the needle cannot be seen prior to injecting. Ø Treatment is either surgical removal of the filler or hyalase injection to remove it.
Advanced : PRACTICAL GUIDE SKIN INFECTIONS Skin infections can be early in onset (24-48 hours post procedure) or delayed (>48 hours). They present with redness, swelling around the area, pain, tenderness and increased temperature to the surrounding skin. They are usually controlled with oral antibiotics but medical attention should be sought depending on the severity- either via the General Practitioner or A&E if the infection is spreading rapidly, or the client is systemically unwell and pyrexic. (Photo shows local skin infection around marionette line injection) VASCULAR OCCULSION LEADING TO BLANCHING, SKIN NECROSIS OR BLINDNESS Vascular occlusions may present in a number of ways and the practitioner must be prepared at all times as they may progress rapidly and consequences can be disastrous. Recognise vascular occlusions as blanching of the skin, dusky discolouration or disturbances in vision (late sign) caused either by emboli of product or direct compression to a vessel. (Photo shows skin necrosis after injection into the nasolabial fold causing vascular occlusion) TREATMENT: Ø Stop injecting immediately. Ø Use a heat pack or a warm flannel to maintain collateral circulation. Ø Hyalase reconstituted and injected to region directly and circumferentially in a 1cm radial pattern. Ø Reconstitution according to guidelines (members’ login area and lectures) and repeated as required after careful assessment and documentation. Ø Appropriate close monitoring and follow up always required.
Advanced : PRACTICAL GUIDE CONSENT/ MEDICAL HISTORY FORM Name: Ms/Miss/Mrs/Mr (delete as appropriate) Address: Postcode: Home Tel: Mobile: Office Tel: Date of birth: e-mail: GP’s name, address & tel: Do you smoke? Yes/No How many per day? Do you drink alcohol Yes/No If ‘Yes’, how many units per week? Are you pregnant or breastfeeding? Yes/No Are you currently taking or have you ever taken any of the following medications? Laxatives/Vitamin E Yes/No S t John’s Wort Yes/No Hormones/contraceptive pill Yes/No Gentamicin/Neomycin Yes/No Steroids/gold injections Yes/No Roaccutane Yes/No Aspirin/pain killers Yes/No Anti-coagulants Yes/No If ‘Yes’ please give details or list any other medication not listed above: Do you suffer from any allergies? Yes/No If ‘Yes’, please give details? Have you suffered from any of the following? Heart disease/angina Yes/No Thyroid problems Yes/No Auto-immune disease Yes/No Arthritis Yes/No Asthma/bronchitis Yes/No Convulsions Yes/No Facial cold sores Yes/No Depression Yes/No High/low blood pressure Yes/No Diabetes Yes/No Stomach ulcer/colitis Yes/No Skin disease (e.g. acne) Yes/No HIV/hepatitis Yes/No Glaucoma/cataract Yes/No Venereal disease/STD Yes/No Bell’s/facial palsy Yes/No Phlebitis (inflamation of your veins) Yes/No Hypoglycaemia Yes/No Myasthenia gravis Yes/No Amyotrophic lateral sclerosis Yes/No Lambert-Eaton syndrome Yes/No
Advanced : PRACTICAL GUIDE Have you ever been admitted to hospital? Yes/No If ‘Yes’, please give details: Have you had any previous surgery (non-cosmetic)? Yes/No If ‘Yes’, please give details: Have you previously had any cosmetic surgery, including eye/eyelid or facial surgery? Yes/No If ‘Yes’, please give details and dates: Have you previously had any cosmetic injection treatments? Yes/No If ‘Yes’, what was treated and when? Have you had any sun bed treatment, dermabrasion, skin peels or laser skin resurfacing in the last 6 weeks? Yes/No If ‘Yes’, please give details and dates: Are you currently undergoing any dental treatment? Yes/No If ‘Yes’, please give details and dates: Do you have any phobias that may affect treatment? e.g. needles or Yes/No blood If ‘Yes’, please give details: Are you particularly prone to fainting, bruising, keloid scarring or bleeding? Yes/No Do you have any other medical/health conditions we should be aware of? Patient name: Patient signature: Date: If you answered ‘Yes’ to any of the questions, your practitioner may ask you for more details to decide if you are suitable for treatment. P rovided as a service to medicine by Galderma (UK ) L td. AZZ20-01-0002d Date of Preparation: February 2 0 2 0
Advanced : PRACTICAL GUIDE USEFUL CONTACT DETAILS/ GROUPS PRESCRIBING MedFx https://www.medfx.co.uk 01376 532 800 INSURANCE Insync Insurance 01202 309521 www.insyncinsurance.co.uk PHARMACEUTICAL PROVIDERS Galderma https://www.galderma.com/uk 01923 208950 CONFERENCES AND KEEPING UP TO DATE Aesthetic Complications Expert http://acegroup.online Clinical Cosmetic and Reconstructive Expo http://www.easyfairs.com/ccr-expo- Aesthetics Conference and Exhibition https://aestheticsconference.com Facial Aesthetics Conference and Exhibition https://www.faceconference.com Aesthetic & Anti-Aging Medicine World Congress https://www.euromedicom.com/amwc- 2020/en/participants/about-amwc-2020.html International Master Course on Ageing Skin https://www.imcas.com/en
www.acquisitionaesthetics.co.uk Contact@acquisitionaesthetics.co.uk
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