BIG IDEAS SHOWCASE 2013 - new technologies for world markets an Enterprise Ireland initiative
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BIG IDEAS SHOWCASE 2013 new technologies for world markets an Enterprise Ireland initiative 25th September, Aviva Stadium
Minister’s foreword Seán Sherlock TD Minister for Research & Innovation Through consistent and considerable and commercialisation of innovative new public and private investment in science, products and services and increase the technology and innovation over the last number of new technology-based start- decade, we now have a strong base of up companies and ultimately help create research expertise within Ireland. With this the jobs we need. In order to benefit from in mind, the Action Plan for Jobs focuses our publicly funded research, we need to on research and innovation as a tool to set ambitious targets – nationally and at build our economy and boost job creation. EU level – to ensure that we maximize the By implementing and commercialising this availability of productive, job creating funds research we can create a stronger, more for Irish researchers. We know from our sustainable economy. own enterprise sector that research and development drives exports and profitability The Big Ideas Showcase illustrates the and helps to secure and grow jobs. quality of research happening in Universities and Institutes of Technology across the The Big Ideas Showcase 2013 provides country. It demonstrates the success of the perfect platform for researchers in Ireland’s national technology transfer system the areas of ICT, Lifesciences & Food and and exhibits the high standard of research Manufacturing, Engineering & Energy with that this country is producing. Steps are the opportunity to meet the investors underway to bring together a lot of existing and business partners that will assist in research activity and involve the enterprise transforming their publicly funded research sector more directly in this research. into the commercial products and services Specifically, the Technology Centres being of the future. progressed by Enterprise Ireland and IDA The Big Ideas you hear about today are the which will play a key role in positioning culmination of a process that is funding Ireland as a recognised centre for applied research and commercialisation and research, supporting the attractiveness which has at its core the aim to support of the State as a location for foreign entrepreneurs and attract investment and direct investment and the growth of Irish investors. Ultimately, this process boosts industry. These Centres work well with and job creation, supports industry, encourages complement research funded by Science overseas investment into Ireland and has Foundation Ireland and other publicly - an extremely positive effect on the overall funded R&D that is happening in Ireland. economy. This Government is dedicated to supporting I would like to commend Enterprise Ireland the transfer of ideas and knowledge created on the success of this annual event. I would in our Higher Education Institutes into Irish also like to congratulate the researchers industry – turning good ideas into good participating in the Big Ideas Showcase this jobs. year. I wish you all every success. As announced in June 2013, €21million in funding has been allocated to the Enterprise Ireland Commercialisation Fund. This will accelerate the development 2013 1
A word of welcome to investors Gearóid Mooney, Divisional Manager Research and Innovation On behalf of Enterprise Ireland, I would Enterprise Ireland can help your company like to welcome you to our annual Big connect with this wealth of talent and Ideas Technology Showcase - the key event investigate the potential for funding in the Irish research commercialisation support. This is allocated in three ways: calendar. Enterprise Ireland’s Innovation Vouchers There will be 21 new investor-ready Initiative allows SMEs and micro businesses technologies showcased today and to commission a small piece of research the market quality of the opportunities with a €5,000 voucher redeemable in the on display is a reflection of the Higher Education Research System. Since commercialisation work that is ongoing 2009, over 3,700 Innovation Vouchers have in Higher Education Institutes throughout been allocated. This initiative helps smaller Ireland. This year’s “Big Ideas” cover companies solve a business problem or take numerous market segments including the first steps into R&D. software, heathcare, fashion, cleantech and Another initiative is the Innovation homeware. Partnership Programme which is tailored Enterprise Ireland is responsible for to support collaborative projects between the development and growth of Irish companies and research teams. There have enterprises in world markets. A key aspect been over 200 companies successfully of achieving this duty is to optimise the flow involved in Innovation Partnerships over the of commercial opportunities arising from last four years and more than 1000 in the the Irish government’s investment in our past decade. national research system. Enterprise Ireland also support companies Evidence of the impacts of research that want to get involved in leading the commercialisation can be seen in the Irish research agenda in their industry through economy, specifically the 110 spin outs our Technology Centre programme. that have emerged from commercialised Technology Centres, a joint venture research since 2009. Enterprise Ireland between Enterprise Ireland and IDA Ireland helps researchers at all stages of the are collaborative research centres that commercialisation pipeline through our are led by industry. Currently, there are 12 Commercialisation Fund with over 400 established Technology Centres with three commercialisation projects funded in the more in the pipeline. These centres work to last four years. an agenda agreed by a consortium of Irish SME’s and multinationals based in Ireland Existing Irish companies also benefit from which share common research goals. direct access to technologically advanced researchers who are focused, efficient and The work presented here at Big Ideas eager to collaborate with industry. This is Showcase 2013 demonstrates the level of an impressive national resource consisting commercial innovation that is nascent in our of more than 4,500 researchers backed by publicly funded research institutes. I invite Government funding. you to engage with the participants, expand your knowledge of the great potential of these innovations and hopefully identify the ideas that best suit your investment and support. 2013 3
Big Ideas schedule overview 09:00 Registration 10:00 Official Opening and Presentation of Commercialisation Awards by Seán Sherlock TD, Minister for Research & Innovation 10:10 Opening Address by Gearoid Mooney, Divisional Manager Research & Innovation, Enterprise Ireland 10:20 Innovation and Research Expo 10:45 Big Ideas Technology pitch session 1 13:00 Lunch 14:00 Big Ideas Technology pitch session 2 16:30 Event Ends 16:45 Evening reception Big Ideas Technology Pitch Session Schedule Time Presenter Big Idea 10:45 Xuemei Germaine MicroGen Biotech 11:00 Wayne Allen Embo Medical 11:15 Hillary Kenna Vizolve Ltd 11:30 Ken Byrne GRASP 11:45 Liam Mullins Lumen on Demand 12:00 Julia O’Rourke Rempad 12:15 Wayne Byrne OxyMem 12:30 Garret Ryan Crescent System 12:45 Kevin McCarthy Aficionado Lunch 14:00 Ronan Clarke Smart Wall Paint 14:15 Paul Leonard DiCast 14:30 Kevin Doherty Gazel 14:45 Miguel Ponce de Leon Mobile Cloud Alliance 15:00 Edward Grant Cipherdocs 15:15 John Tinsley Iconic Translator Machines 15:30 Mark Bruzzi Vetex Project 15:45 Mark Hughes Style-Eyes 16:00 Eamon Murphy MR Gum Technology 16:15 Pat Hobbert Vasgard 16:30 Kevin Koidl Wripl 16:45 Deirdre Hogan Ata-Bot 4 2013
Today’s chairperson John Lynch John Lynch is a strategic business knowledge. As well as working with thinker with strong analytical skills to a range of start-up and early stage direct and drive business growth and companies, he was CEO of Merrion profitability. John has an impressive Pharmaceuticals plc, where he worked track record of leading growth from start up in 2004 until 2007. Until businesses and also of attracting 2007, he also held senior positions in and building experienced senior a number of countries with Abbott teams, including building a business Laboratories between 1989 and 2003. from the ground through IPO. John He served on the Irish Government’s successfully completed several rounds Innovation Taskforce in 2009/10. of equity fundraising , negotiated Self motivated and dynamic, John major contracts, Government price is continuously seeking ways to negotiations and influenced health improve both business and personal policy. John is experienced in out- performance and add-value. He has a licensing and acquisition, in-license of huge interest in new technology and products and the generation of new building strategies and routes to bring product ideas. it to market. He has worked with a John has worked extensively in the number of the presenters in the Big life sciences industry both in Ireland, Ideas Showcase, aiding them to bring the USA, UK and internationally for their technologies towards the market. the past 25 years. Over that time he John’s advice to technology has assumed many roles which have innovators is to ensure that the four had a strong emphasis on innovation main foundations of any start-up and new product development - these - innovative technology with clear include CEO, Non-Executive Director, Intellectual Property Rights, a validated consultant, mentor, International and viable market accompanied by a Business Development Director and strong business model and a strong Commercial Director. He has also entrepreneurial team. These are all worked in new product development, part of the innovation process from operations, finance and sales & the start and move forward in parallel. marketing. Through his extensive Get the best team around the table to work with both start-up businesses work on your idea as soon as you can, and large multinationals, he has and a great idea could become a great experienced a very broad range of company. life sciences technology areas such as drug delivery, drug development, medical devices, medical diagnostics and medical nutrition. This has giving him a great breadth of industry 2013 5
Meet this year’s presenters Dr. Xuemei Germaine MicroGen Biotech Ltd 8 Wayne Allen Embo Medical 9 Hilary Kenna Vizolve Ltd 11 Ken Byrne CEO Grasp Wearable Technologies 12 Liam Mullins Lumen-on-Demand 13 Julia O’Rourke REMPAD 15 Wayne Byrne OxyMem 17 Dr. Garrett Ryan Crescent System 18 Kevin McCarthy Aficionado 19 Ronan Clarke Smart Wall Paint 20 Dr. Paul Leonard Innovamab 21 Kevin Doherty Gazel 23 Miguel Ponce De Leon Web Real Time Communications 24 Ed Grant CipherDocs 25 Dr. John Tinsley Iconic Translation Machines 26 Dr. Mark Bruzzi Vetex 27 Dr. Mark Hughes Style-Eyes 29 Eamon Murphy MR Gum Innovation 31 Pat Hobbert Vasgard 32 Dr. Kevin Koidl WRIPL 33 Dr. Deirdre Hogan Ata-Bot 34 2013 7
MicroGen Biotech Ltd Dr. Xuemei Germaine Environmental clean-up solutions Contamination of urban environments One Stop Biotech Solutions and water sources is a worldwide issue. It severely affects our eco-system MicroGen Biotech’s ready-for-market functions and human health. MicroGen products and platform technologies Biotech Ltd is a bioremediation include site-specific microbial products, company based in Ireland which has EcoPileTM technology, Plant-Microbe developed a number of environmentally technology and Bioremediation-Biofuel friendly clean-up solutions. We use technology. Providing innovative, clean, natural novel bacteria and plants to bioremediation solutions for the clean clean up toxic environmental pollutants up of large scale contaminated sites from soils and water streams. is key for the success of the company which was spun out of IT Carlow. Dr. The goal is to provide complete clean up Germaine indicates the “initial target solutions for problem sites using unique market for this technology is China combinations of natural soil degrading and we are actively seeking to secure bacteria and site specific organisms, investment to accelerate our growth”. coupled with novel engineering and treatment processes. MicroGen Biotech’s solutions are natural, site specific and highly cost effective. Notes 8 2013
Embo Medical Wayne Allen Safe, cost effective embolisation Embolisation is a procedure to shut Next generation of embolisation down blood flow in a diseased vessel or to a diseased organ, for example Their product, the Caterpillar is a one- embolisation can be used to shot embolisation device, that embolises stop blood flow to a tumour. a vessel with just one implant and takes just five minutes in total to deploy. The Worldwide, there are approximately Caterpillar has inbuilt anti-migration 200,000 procedures done each year. features to ensure that only the intended Current practice is to use multiple coils vessel is blocked by the procedure. (about the width of a strand of hair) to shut down the vessel, requiring The development team, Colin Forde and an average of nine coils in any one Wayne Allen, who have over 25 years procedure. There are two key issues with of medical device industry experience, the use of coils: took part in the Bioinnovate Ireland programme, which allowed them to 1. the coils can migrate away from the become a “fly-on-the-wall” in medical target vessel causing unintended procedures over a three month period. blockages elsewhere in the body Having witnessed several embolisation 2. it takes five minutes to implant each procedures, they realised that current coil, resulting in 45 minutes of a technology could be greatly improved, physicians time to put in the coils with the effect of improving patient alone. safety, reducing procedural time and therefore cost to the healthcare system. After 18 months researching the problem at NUI Galway, the product was developed and has already undergone successful animal studies. The team objective is to “make the Caterpillar the market leading peripheral embolisation device, and is currently fund-raising to bring the technology through regulatory approval to commercialisation” explains Wayne. Notes 2013 9
Vizolve Ltd Hilary Kenna visualising search for education, research and libraries Based out of the Media Cube in IADT ‘One query, one screen and all Dún Laoghaire, Vizolve have developed the answers’ a personalised search and discovery application called SeeSearch. Search behaviour has not evolved: users simply keep retyping new queries SeeSearch is initially focusing on the to refine their searches rather than education, research and library sector. laboriously clicking through pages The technology searches through of results. SeeSearch changes all of everything the college or library owns; that because it is very different to the books, e-books, databases, e-journals, traditional text-based results we are dvds, multimedia repositories, etc – as all accustomed to seeing on search well as content available on the web, engines. and can be personalised to suit your interests. SeeSearch provides a single The SeeSearch display is very visual place to search all of your content and gives hundreds of times more resources, making it possible to find results in a single screen, but in a very resources from multiple sources with understandable and structured way, one search, instead of having to search meaning you are much less likely to several databases individually. need to keep searching over and over again, and more likely to find what Not only does SeeSearch find the most you want thereby increasing search relevant search results, it also presents productivity. SeeSearch presents an them in a new and exciting way through easy-to-use visual search experience visualisation. When you search through that gives you much more results in a any of the current search engines you single screen, and it’s available on your get a text based list, most people don’t desktop, tablet and mobile. go beyond the first or second page of the results. With SeeSearch you get a Currently integrated with hundreds of visualisation of your search results, this thousands of books, media and article means that instead of seeing text-based content, the technology is a horizontal results you see a visual representation solution and has applications across a of the book and DVD covers etc. You number of areas including e-commerce, also see graphical representations of the travel and enterprise search. So for areas your results are coming from. anyone interested in web and mobile technologies, content and big data access and the general discovery space, SeeSearch will ‘give you all the answers’. For more information please visit www.vizolve.com Notes 2013 11
Grasp Wearable Technologies Ken Byrne CEO Real-time movement and physiological measurement Grasp Wearable Technologies is an One of the key advantages of the Grasp emerging technology design services Run system is that the measures can and product development company. be taken outside an instrumental lab Grasp creates wearable products for the setting. The system is comprised of a consumer market which addresses real small lightweight device attached to world problems in fitness, sports, health each shoe coupled with a wrist-based and consumer electronics in the fast device for real-time feedback to the user growing wearable technology market. while running. The company is developing novel Smartphone and tablet/ web apps applications of its technology to complete the user experience and measure complex human movement and provide the user with flexibility on physiological characteristics through usage modes, personalisation wearable products and systems. options and presents comprehensive information. One of the distinguishing elements of this product is that it Flagship Product - supports runners at all levels providing Grasp Run System the user with the most appropriate measures and feedback for their abilities Grasp aim to provide helpful, user and aligned with their personal goals. friendly and engaging products for The system has been developed in use in everyday settings. collaboration with athletes, sports The first of their products is the Grasp therapists and healthcare professionals. Run System which provides users with “Our objective is to secure investment useful information on the biomechanical to build out the company, our flagship and physiological characteristics of their products and our go to market running style. strategy.”, explains Ken Notes 12 2013
Lumen-on-Demand Liam Mullins Faster Safer Intervention The Lumen-on-Demand technology is Opening a channel designed to reduce the procedural time of interventional surgeries which require Lumen-on-Demand provides a channel the use of a catheter. (or lumen) in the catheter that can deliver fluid into the patient without The new “Lumen-on-Demand” feature having to exchange the catheter or is a smart add-on to catheters and guidewire. The channel is concealed there are a number of benefits in until the physician injects fluid into the doing this such as improved safety, channel. The channel expands only on through reduced radiation exposure demand ensuring catheter performance to the physician and patient, and is uncompromised during delivery, increased cost effectiveness achieved navigation, and removal. by decreasing procedural time (approx. Developed in NUI Galway, the €1,000 per hour). Additionally the technology can be applied to any clinical volume of contrast fluid (which can be area in the endovascular space, and to toxic) required to navigate and monitor over 1 million procedures annually. the catheter may be reduced. “Our objective is to identify a co- The team behind Lumen-on-Demand development partner to bring this spent 3 months observing cathether technology to the clinic where it can based procedures and discovered that reduce procedural cost and improve the there are a number of time consuming safety of procedures.” explains Liam. actions that are constantly repeated, such as removing and re-inserting guide wires from catethers. Based on these observations the team identified a need to streamline procedures by eliminating the requirement to remove the guidewire for contrast fluid injection, and have developed the Lumen-on- demand technology to meet this need. Notes 2013 13
BIG IDEAS SHOWCASE 2013 new technologies for world markets an Enterprise Ireland initiative Enterprise Ireland presents the first ever Technology Centre Forum. Technology Centres are collaborative entities established and led by industry. They are resourced by highly qualified researchers associated with research institutions who are empowered to undertake market focussed strategic R&D for the benefit of all industries. Come and see our exhibition and hear from companies like yours who have benefited from the Technology Centre Programme For more information please visit www. enterprise-ireland.com/techcentreforum 2013 14
REMPAD Julia O’Rourke Next generation reminiscence therapy Dementia is a growing problem both in The REMPAD system incorporates Ireland and globally. Current projections content management tools and training indicate that there will be a significant to provide a fully automated solution increase in the number of people with that utilises online data archives to dementia in Ireland, from approximately provide a clinical support tool. This 40,000 at present to 100,000 by benefits nursing home residents and 2036. Globally 4.6 million people are their carers. REMPAD is deployed to diagnosed with dementia each year. 30% nursing homes as a Web App and of those will reside in nursing homes for utilises existing wi-fi infrastructure within the last years of life. care homes. With no cure for dementia and the “REMPAD reduces overhead and failing of pharmacological interventions resource costs for care homes whilst to address this problem, healthcare has improving social connection amongst focused on enhancing Quality of Life. residents and staff”. Reminiscence therapy is a validated, evidence based approach which has been found to improve nursing home Advantages residents mood and wellbeing and also have a positive impact on cognition REMPAD has been successfully trialled in and communication. nursing homes with residents suffering from dementia where it has been found to maintain wellness and improve mood through social interaction. The Next Generation of Reminiscence Therapy “We have a pipeline of customers waiting for REMPAD to come on the REMPAD, a novel connected-care market” says Julia O’Rourke, “We are solution emerging from research carried looking for investment to bring this out in DCU, delivers next generation valuable a much needed resource to reminiscence therapy as part of them”. person-centered care in nursing homes for residents with dementia. Notes 2013 15
16 2013
OxyMem Wayne Byrne Changing the economics of wastewater treatment Activated Sludge has been the Bubble-less aeration cornerstone of wastewater treatment for the last 100 years. This is a very energy Researchers at UCD have developed intensive process due to the requirement OxyMem which does not rely on a to provide oxygen, via aeration, to the bubble to transfer oxygen, instead pollution degrading microorganisms OxyMem uses gas permeable so it can be discharged back to the membranes, that allow oxygen to be environment.Typically 2.5 percent of a transferred directly to the wastewater developed nation’s electricity (US, UK, treating bacteria. OxyMem is capable of Ireland) is used for the treatment of achieving up to 100% oxygen transfer wastewater and aeration accounts for efficiency, as no oxygen is lost to the 60% of this demand. The reason the atmosphere. The results are a four fold demand is so high, is that large volumes saving on energy costs when compared of air (21% oxygen) must be forced down to forced aeration. to the bottom of deep tanks to create In addition to the energy benefits, bubbles. The bubbles then travel to the OxyMem’s patented system uses fewer surface and during the short journey chemicals, has lower pumping costs, transfer some of the oxygen to the water is built on a reduced physical footprint where it is available to be used by the and has the added benefit of being fully microorganisms. Once at the surface automated. the air bubbles escapes back to the The system comprises a turnkey aeration atmosphere resulting in a loss of 60-70% system for the wastewater market which of the potential oxygen. has been valued at 4 billion euro and is expected to grow to over 6.5 billion euro in the near future. OxyMem is the first to deliver this technology at a commercial scale and has a full size unit on test at Severn Trent’s Minworth site, the second largest water treatment plant in the UK. “Our objective is to secure a €3 million Euro investment to fully develop our manufacturing/extrusion capability” says Wayne. Notes 2013 17
Crescent System Dr. Garrett Ryan Hypertension – a nerve knockout solution Hypertension, or high blood pressure, Garrett and his team have developed a is a significant problem in the modern novel drug delivery system; the Needle world affecting large proportions of Catheter System delivers drugs safely the world’s ageing population. Many of and effectively to a target location, at a those affected can control the condition specific depth where the drug diffuses using a cocktail of drugs but there is a around the artery. This procedure significant proportion who are resistant results in minimal damage to the vessel to current pharmaceutical therapies. wall, reducing the risk of late stage complications. Clinicians have shown that by destroying the nerves within the wall of the renal artery, they can succesfully lower blood pressure in patients resistant to Advantages medication. The majority of devices Renal denervation is predicted to in development use energy based be a game changer in the treatment systems to destroy the nerves (known as of hypertension, as well as potential sympathetic nerves) by burning through indications such as sleep apnea, chronic the artery wall. While all have shown heart and kidney failure and diabetes. efficacy in the form of reduced blood This drug delivery solution should pressure, there is the potential for long represent a more cost effective solution term damage to the inner surface of the to energy based systems being sold in artery. the market at present. “Our objective is to secure investment that will facilitate the creation of a start- Finding a cure for resistant up company dedicated to bringing the hypertension Crescent System to market.”, says Dr. The Chemical Renal Denervation project, Ryan. emerging from research carried out at Trinity College Dublin and NUI Galway, has developed an alternative solution to target the sympathetic nerves. Notes 18 2013
Aficionado Kevin McCarthy Online management of organisational expertise & skills Large multinational corporations with Somewhat comparable to Linkedin, thousands of employees over multiple Aficionado is distinct in that expert geographical locations, by the nature of doesn’t need to regularly update their their scale and disparate locations, have profile with recent work. difficulty in keeping track of what teams The expert profile is built automatically are doing in other locations and which and this was deliberate because people experts are on which teams etc. generally only update their information sporadically meaning the data decays Aficionado is a platform for the location and becomes less useful very quickly. of expertise, and management of expertise, across an organisation. This Initially, the prototype was developed technology can be used internally within for the research market. Aficionado was an organisation from an administration able to tap into the wealth of document or HR point-of-view, but it can also be repositories in seven Irish institutions, used externally to showcase expertise use publication outputs to build rich and skills. profiles of researchers. People can search for particular experts or skillsets Expert engagement and across all universities in Ireland. management Aficionado has potential in a wide This Cloud-based software solution uses variety of sectors such as government, document repositories or other streams pharma, banking & finance and of information, such as internal social professional consulting firms and networks or Twitter streams to build an the professional recruiting market. expert profile of the individuals and then “We have come to Big Ideas to talk to hang search and discovery services off interested investors regarding seed the profiles. funding for our business” explains Kevin. Notes 2013 19
Smart Wall Paint Ronan Clarke Whiteboards with a difference Smart Wall Paint is a breakthrough Rapid Growth concept – a novel paint that when applied to any smooth surface, Smart Wall Paint Ltd was established transforms it to a wipe-on/wipe- by Ronan Clarke in 2012 and already off whiteboard surface. Smart Wall has a significant presence in Ireland, Paint is working with CREST ( Centre UK, Europe, Australia and Canada. for Research in Engineering Surface The company is growing rapidly with Technology) at DIT through the its workforce of six set to double in Innovation Partnership programme the coming months. In addition to its and is developing generation three of five English language ecommerce sites, its product range, which I will bring a Smart Wall Paint will launch Italian, unique new product to the market in German and French language sites 2014. Smart Wall Paint is used primarily in September. by Business and Educators to change Roughly 90% of the product is exported the way they the communicate and through both online and channel collaborate. partners such as large stationery Smart Wall Paint is already in production companies. Smart Wall Paint is also and selling globally. Customers already represented through distributors in UK, using Smart Wall Paint include large Hong Kong, Dubai and Singapore with and small businesses, schools and this route to market set to increase universities such as Google, Twitter, significantly throughout 2014. Facebook, Marks & Spencer, Tesco, “Smart Wall Paint changes the way Microsoft, Trinity College, Glenstal people work together by turning Abbey and hundreds more all over the ordinary rooms and walls into working world. spaces that help people engage, collaborate and create.” Notes 20 2013
Innovamab Dr. Paul Leonard Innovation in monoclonal antibody discovery Pharmaceutical and biotechnology with a unique effect and the potential companies are continuously looking to create the next blockbuster drug. for new cutting edge technologies to Researchers currently run exhaustive, improve their ability to discover and lengthy and expensive experiments to develop new drugs. The former stars of test antibody-producing cells in order the show were small molecule drugs but to identify the MAbs with therapeutical the drug development market has now potential that are most suitable for moved towards larger biological drugs clinical trials. Technology has not such as monoclonal antibodies (MAb) kept pace and this process has been and it is expected that these drugs will described as like searching the internet account for 60% of market growth in the without Google. future. However, there is one key factor that USP determines how many new drugs are developed and the final market price Innovamab’s multi disciplinary team at of approved new drugs: the cost of DCU has developed a technology called discovering and bringing a new drug DiCAST which is a new technology to market. This cost is driven upwards solution for the early stages of MAb by the fact that 95% of drugs in discovery. DiCAST improves the speed development fail for reasons such as and quality of screening not only by toxicity or lack of efficacy in clinical analysing vastly more cells at one time, trials. but also by performing several steps in one iteration (which can take weeks with other technologies). The combination of these patented inventions and know how Looking for the “Golden Egg” provides a radically improved answer to the question of ‘how can I find a one in a Drug development companies have million MAb with greatest certainty and established huge banks of monoclonal greatest probability of success?’ antibodies. As a result, the problem is not in how to generate vast new “We are looking for investment to build amounts of monoclonal antibodies but a company around the technology and rather how to test and recognise their to take it to the world market”, explains potential and find the one rare MAb Paul. Notes 2013 21
Gazel Kevin Doherty Reinterpretation of household products Gazel is a new company creating Thoughtful, enriching & inviting products for the home that marry usability and style with a cutting edge This product has become the catalyst design focus. The flagship product, the for the team to spin out a premium Effortless Clothes Hanger is a sleek and homewares company, and is the first stylish reinterpretation of a household in a pipeline of products spread across staple and showcases the design skill of the different areas of the home, from the designers Kevin Doherty and Ronan bedroom to kitchen to living room. Murphy, both Researchers at the Origin8 The Gazel brand will target the growing Innovation Hub at NCAD. niche of urbanised and sophisticated consumers throughout Europe, who seek value-added and innovative Imaginative lifestyle products products. for the home The team is seeking investment to bring The Gazel duo are ‘rethinking the their exciting products to market. everyday’ to provide a richer experience for people, by elevating the ordinary through inspired design. Kevin and Ronan take normal household products and turn them into convenient and modern objects of real beauty and distinction. The novel concept for the Effortless Clothes Hanger took an everyday object and reimagined it with universal design in mind – it allows all manner of clothes to be hung with minimum effort and maximum comfort. The hanger even slips into fully buttoned blouses and shirts. Notes 2013 23
Web Real Time Communications Miguel Ponce De Leon Web real-time communications This web platform for mobiles, laptops Collaborate and Communicate and desktops enables voice, video online in real time and instantanous collaboration using your web browser by default to deliver Developed by the research organisation communications in real time. the TSSG, the business model has been built around assisting mobile operators The collaboration technology allows in Ireland, Europe and internationally. you to connect your web browser Given that the mobile market has peer to peer enabling voice & reached saturation and the price of video conversations, screen sharing calls is dropping, mobile operators need interactions and game playing all at the additional business productivity tools same time. that they can offer companies. This This system even allows a person to product offers business customers a use their existing social networking range of different collaborative options environment to take a call from someone such as having conference calls, and on their mobile phone. context-based communications, being able to see each others screens and The platform facilitates any two work on documents in real time using computers finding each other via a web the web. browser so that they can connect and communicate. There’s no longer a need “We’ve gained traction in the classified to coordinate and synch up Skype id’s ads market, and require assistance to etc as your existing Facebook, Twitter, accelerate that traction and explore mobile number can be used to connect additional revenue streams.”, explains your computers and communicate using Miguel. the peer to peer technology. The platform also exposes its p2p real time features to web application developers via API’s, allowing them to integrate the platform into their web service. Notes 24 2013
CipherDocs Ed Grant Cloud data encryption & control Many companies today are using the already been encrypted in real time Cloud to store, create and share data when the documents were created or while others have serious concerns shared. This means that even though the driven by both compliance and the data is held in the Cloud, if a third party desire to control their data at all times. wishes to access the data, or it has been CipherDocs allows corporate users of shared with someone it shouldn’t have Cloud platforms, particularly those using been, all they will see is cipher text. Office 365 and Google Apps, to encrypt the documents they are creating, sharing or storing in real time and allows The key to encryption them to retain complete control of who can access the data. CipherDocs has a very simple proposition: take control of your data in Without using CipherDocs encryption, the Cloud in real time. The only way that Office 365 data is stored, shared the information that has been encrypted and created in a clear text form. This by CipherDocs can be accessed is precludes companies in some regulated by sharing a key which you control industries and certain jurisdictions from – without the key, the data is never storing data in the cloud while other disclosed. companies simply have concerns over data control and the threat of a 3rd “Our objective is to raise up to party being able to gain access. If the €500,000 to complete and launch our corporate user such as a bank, health Microsoft Office 365 solution.”, company or insurer, has deployed explains Ed. CipherDocs service then that data has Notes 2013 25
Iconic Translation Machines Dr. John Tinsley High quality cloud based patent translation Patent language translation is a long and The IPTranslator provides the technical tedious process. With long sentences content required in a cost effective and technical constructions it is very manner, it translates to an excellent difficult and time consuming exercise, quality in a very short amount of time, this has resulted in 75% of the cost of leading to a higher level of accuracy and filing a patent coming from translation. productivity and resulting in significant savings for customers. Patent translation is a specialist skill performed by subject matter experts. This novel cloud-based service can be It is crucial that each translation is of a sector-adapted to target high growth very high quality to ensure that it meets vertical markets within the overall all of the legal requirements. Consumers translation industry. want more for less, and sooner, all of Resulting from three years R&D, the this has led to demand way outstripping company already have their first paying supply. customer on board, the service is also being trialled by a number of potential clients around the world. Facilitating the Translation industry and beyond “Having launched our flagship offering we are now keen to speak with people Iconic Translation Machines, a spin-out who feel they could help accelerate company from DCU, have the solution - our growth and see Iconic Translation they have developed advanced Machine Machines fulfill its potential”, explains Translation technology to translate John. one language into another. Their first flagship product is IPTranslator which is targeting the Patent and Intellectual Property (IP) sector. Notes 26 2013
Vetex Dr. Mark Bruzzi Next generation clot removal Vetex is an interventional device for the chronic, lifestyle-limiting symptoms such treatment of Deep Vein Thrombosis, as swelling, pain, and ulceration of the which is the formation of a blood affected limb. clot inside the leg. This can happen Other therapies focus on mechanically for a variety of reasons associated disrupting and/or dissolving the clot with surgery or anything that causes with limited success and often requiring a restriction in blood flow within the long term treatment in an intensive care venous system. setting, resulting in significant cost to In the US alone, it is estimated that the healthcare system. DVT causes 600,000 people to be hospitalized each year, with the resulting Pulmonary Embolism (PE) leading to Efficient and effective more than 100,000 deaths. DVT and PE clot removal are responsible for 1 in 10 hospital deaths annually (US figures). Some estimates The Vetex device can catch large suggest that these conditions cause volumes of the clot in a matter more deaths each year than breast of minutes reducing the need for cancer, AIDS, or motor vehicle incidents. thrombolitics and the need for long term stay in the intensive care unit. Vetex was developed in conjunction The device has three component parts with Gerry O’Sullivan, an interventional including a macerating and extraction radiologist in Galway and leading expert mechanism attached to a basket, this is in the treatment of the disease. He inserted into the venous system behind identified a problem and worked with the knee and pushed to the location of Mark Bruzzi, a biomedical engineer the clot. The device’s efficient capturing and his research team to create a novel mechanism can then extract large device to treat the condition. volumes of clot across a wide range of Current standard therapy for the disease vessel diameters. involves the use of anti-coagulation “Our objective is to secure investment (blood thinning) drugs but while this and a commercial team to bring this limits the development of the clot, it technology to the European and US does not dissolve it which can result in market.”, explains Dr. Bruzzi. Notes 2013 27
Style-Eyes Dr. Mark Hughes The future of fashion retail The concept is quite straight forward: Searching for a needle Style Eyes is a search engine that will in a haystack find that dress, pair of shoes or handbag that you have spotted out and about As creator Mark Hughes explains; if you and want to buy. ever looked for a specific garment in a search engine, you’ll know you get Simply take a picture with your Smart thousands of results with hundreds of Phone and using their image recognition these coming from online catalogues, technology – and a network of retail making online searching labourious and partners - Style Eyes allows you to source in many cases fruitless. the item and buy it! While image recognition is becoming After nine months of development, Style very popular and will over time become Eyes launched onto the Irish market at ubiquitious, clothes have always proved Dublin Fashion Festival 2013. difficult to capture because they deform with peoples bodies, so visually Over 300 of the leading fashion retailer’s that’s a real challenge. Style Eyes have dresses, skirts, tops, bags, shoes and developed the technology to get around accessories are on the Style Eyes system this. (all with commercial agreements in place) so that all you have to do is Designed for ‘anyone interested simply take a picture, and the app will in fashion’, the multi platform app source it for you. is free to users as revenues come from agreements with retailers via traffic delivered to retailer sites and a percentage of any purchase. Mark is looking to meet people who can “help Style-Eyes reach its full potential”. Notes 2013 29
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MR Gum Innovation Eamon Murphy Biodegradable, non-stick chewing gum Chewing gum has become an enormous Eamon is an experienced food executive littering problem and negatively affects and an Enterprise Ireland Business the environment. Because of its non- Partner and has spent considerable biodegradable nature, gum does not time seeking out commercial innovation dissolve or decompose and each opportunities at Irish third level piece left untreated lingers around for institutions. decades. Eamon Murphy and Dr Liam The promoters will work with the Ryan have teamed up to develop and experienced team at Agri-food and launch their solution to this world wide Biosciences Institute (AFBI) in Belfast problem, a biodegradable, non-stick to further develop and scale-up the chewing gum. technologies. The duo have already developed prototypes and aim to launch a chewing gum with improved functionality over The Mission products currently on the market. The solution uses technology originally The mission of MR Gum Innovation developed by Professor Elke Arendt and is to develop and launch an exciting, Dr Ryan in UCC, supplemented by other innovative and environmentally-friendly related technologies to provide a food- chewing gum brand. The technology based alternative to the current rubber/ also has multiple applications across latex based gum products. both food and pharmaceutical fields. The gum will be produced using a MR Gum Innovation is currently at multi-stage development platform, prototype stage and is investment ready. combining a number of novel processing “Our objective is to secure investment techniques. This will allow for the and support to help us turn what should targeted and time-controlled release of be into what is.”, says Eamon. functional molecules to create a variety of customised products including longer lasting and multi-flavoured gums. Notes 2013 31
Vasgard Pat Hobbert Varicose vein prevention Globally, one in four people will suffer A first of its kind from varicose veins with 30% of females and 25% of males presenting symptoms The device is a sensor which, after at some stage in their lives. Besides initial measurements and fitting, being a cosmetic problem, varicose is worn by the patient beside the veins can be painful, especially while knee joint for 48 hours. standing. Up until recently, little could The sensor continously monitors the be done to treat the early stages of the venous blood pressure of the patient condition. and identifies the patient’s specific The only option available to people behaviours that lead to harmful venous was surgical intervention (such as pressures. The technology involves vein stripping procedures) in order to complex, patent-pending, algorithims treat the more advanced stages of the which calculate the leg’s venous blood disease. The main controllable factor pressure, providing personalised, in the development of varicose veins is highly specific feedback and lifestyle “venous hypertension” or high blood advice. The product will be supplied pressure in the veins which causes to clinicians to enable them to provide the veins to stretch and distort. By a new varicose vein screening service reducing this venous blood pressure for people with, or concerned about throughout the course of the day, one developing varicose veins. can prevent varicose veins from forming Connected via desktop computer or worsening. An NUIG research team software, the sensor technology will have developed the VASGARD sensor, a automatically generate an in-depth, technology-based product which non- high value, consultation report which is invasively measures venous pressure in easy to understand which the patient the veins of the lower leg. The device can take away with them. The avoidance also offers an opportunity to proactively of deteriorating veins by following that screen a patient to determine what life- advice will be significantly beneficial to style factors are predisposing them to the potential patient. varicose veins and to take the necessary “Our objective is to secure funding, avoidance action. ideally from Investors, who can provide expertise in addition to finances“, says Pat. Notes 32 2013
WRIPL Dr. Kevin Koidl Driving traffic to online businesses The number of online businesses is Interest profile exploding, with global e-commerce sales topping $1 trillion for the first time WRIPL’s aim is to build a long term in 2012. But, how do you make your interest profiles in consumers. One of business stand out in this busy space? the USPs is the fact that it doesn’t use And how do you drive more traffic to Cookies so developing an interest profile your site? over the long term on behalf of its online partner’s allows WRIPL to correlate with WRIPL has the answer, WRIPL that partner’s content and push relevant technology will suggest relevant stories/ articles based on interest. products from your site to consumers who have expressed an interest in the A unique feature of WRIPL is that the area. service can be applied to different websites and services the consumer Consumers sign up to WRIPL and is using. This allows WRIPL to unify create an interest profile, WRIPL then the users experience and recommend constantly updates the profile from relevant content based on the users across the web by gathering information broad interests. As it is service based about their activities – what they are WRIPL can continue the browsing reading, what they are clicking on etc. experience across devices such as This interest profile can recommend Mobile, Tablet and Desktop. articles and products that are relevant and interesting to the user over time. WRIPL’s technology can increase the user experience by having a greater If a reader is clicking on content about relevance of content and also the Brian O’Driscoll for instance, WRIPL will revenue of the online partner by driving suggest rugby related content to the traffic to their website. consumer. “Our objective is to reach out to additional customers and secure investment”, says Kevin. Notes 2013 33
Ata-Bot Dr. Deirdre Hogan Targeted online advertising Nowadays, more and more companies Processing noisy language are concentrating their efforts on online naturally advertising, print ads are slowly but surely becoming a thing of the past. The technology is born out of DCU which has an expertise in technology for Ata-Bot is a technology which looks at accurately processing human language. user generated content such as Twitter User-generated content contains lots posts, publicly available Facebook of typos, errors, slang and emoticons comments and content generated on and this degrades the accuracy of most forums. Ata-Bot can understand the text analytic tools, which are trained intent expressed by the customer in the on well edited text such as newspaper threads of these conversations, which it articles. Ata-bot technology is trained links back to the service provider. The to accurately understand “noisy” user- service provider in turn delivers more generated content. relevant ads to the customer in real time by offering products or services that The digital advertising industry directly address the needs the person is generated a record-breaking $9.6 expressing online. billion in revenue for Q1 2013. Currently advertisers can target consumers Ata-Bot was trialled by analysing through a variety of ways, including Twitter data in relation to the telecoms through demographic information and domain, seeking out users who have browsing history, Ata-Bot has created a expressed an intent to switch provider. niche approach to targeting consumers This information would be very useful to by utilising their own user generated rival service providers who can target content. consumers who are possibly looking to ‘churn’. In the same way, people “Ata-Bot is attending the Big Ideas talking about when is the latest version Showcase with a view to meeting of a phone coming out are possibly potential Technology Partners to trial expressing an intent to buy a new our software” says Hogan. product. Notes 34 2013
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WE’RE OPEN TO NEW IDEAS ESPECIALLY YOURS It all starts with a cup of coffee... ● Whatever your research work’s nature or stage ● Whatever the stage of your career ● Whether you are working alone or in a team ● Whether you have proof of concept or not The Commercialisation Fund programme enables researchers to develop innovations through Commercial Case Feasibility and Commercialisation Fund Project grants. Get in touch to find out how we can help you take your research to the next stage. www.enterprise-ireland.com/commercialisation
THANKS FOR ATTENDING SHOWCASE 2013 25th September, Aviva Stadium CONTACT big.ideas@enterprise-ireland.com Research and Innovation Business Unit Enterprise Ireland The Plaza East Point Business Park Dublin 3 www.enterprise-ireland.com/bigideas © Enterprise Ireland Sept 13 - (338)
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