Antimicrobial Coating Solution - Singapore Asahi Chemical & Solder Ind. Pte Ltd Asahi Lifecare Technology

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Antimicrobial Coating Solution - Singapore Asahi Chemical & Solder Ind. Pte Ltd Asahi Lifecare Technology
Antimicrobial
            Coating
            Solution
Singapore Asahi Chemical & Solder Ind. Pte Ltd
          Asahi Lifecare Technology

                  KH Chew   Nov 2021

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Antimicrobial Coating Solution - Singapore Asahi Chemical & Solder Ind. Pte Ltd Asahi Lifecare Technology
Table of Contents

  • Development Background For AHC
  • Antimicrobial Coating Technology
  • Antimicrobial Coating vs Disinfectant
  • Safety Test
  • Anti-Bacteria Test Report
  • Anti-viral Test Report

                       KH Chew   Nov 2021

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Antimicrobial Coating Solution - Singapore Asahi Chemical & Solder Ind. Pte Ltd Asahi Lifecare Technology
Development
Background For
     AHC

    KH Chew   Nov 2021

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Antimicrobial Coating Solution - Singapore Asahi Chemical & Solder Ind. Pte Ltd Asahi Lifecare Technology
Mankind has faced, and will continue to face infectious
diseases of different scales              Worst Hit Countries by COVID19 2021
                                                            #      Country         Total Cases Total Deaths                  Population
                                                                  WORLD             248,023,907   5,024,258
                                                            1     USA                   46,931,766            767,441          333,590,717
                                                            2     India                 34,285,814            458,470        1,398,087,214
                                                            3     Brazil                21,814,693            607,954          214,573,835
                                                            4     UK                     9,097,311            140,672           68,361,530
                                                            5     Russia                 8,593,200            240,871          146,017,940
                                                            6     Turkey                 8,061,666             70,828           85,548,479
                                                            7     France                 7,168,743          1,117,689           65,466,165
                                                            8     Iran                   5,944,599            126,616           85,425,266
                                                            9     Argentina              5,289,945            115,989           45,748,561
                                                            10    Spain                  5,011,148             87,368           46,778,937
                                                            14    Indonesia              4,245,373            143,457          277,378,151
                                                            19    Philippines            2,792,656             43,404          111,524,107
                                                            20    Malaysia               2,476,268             28,975           32,918,484
                                                            24    Thailand               1,927,763             19,338           70,033,589
                                                            26    Japan                  1,722,966             18,275          125,959,810
                                                            40    Vietnam                  932,357             22,205           98,505,968
                                                            60    Myanmar                  500,950             18,714           54,896,111
                                                            74    South Korea              367,974              2,874           51,328,044
                                                            93    Singapore              200,844                 421           5,911,678
                                                             99   Australia                173,198               1,756          25,894,127
                                                            109   Cambodia                 118,702               2,800          17,027,193
                                                            113   China                     97,314               4,636       1,439,323,776
                                                            132   Laos                      41,829                  70           7,416,186
                                                            160   Taiwan                    16,421                 847          23,874,275
                                                            169   Brunei                    13,321                  89             443,062
                                                            172   Hong Kong                 12,350                 213           7,578,061
                                                            179   New Zealand                6,723                  28           5,002,100

                                       KH Chew   Nov 2021
                                                                  ASEAN         Data: Worldometer's COVID19 data 02Nov2021

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Antimicrobial Coating Solution - Singapore Asahi Chemical & Solder Ind. Pte Ltd Asahi Lifecare Technology
Transmission of Infectious Diseases is via skin contact with
contaminated surfaces

                                        Wash our hand often is
                                      recommended but difficult
                                           to be practiced

  Anti-microbial coating on common areas will kill
bacteria and virus and reduce the transmission rate
               of infectious deceases

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Antimicrobial Coating Solution - Singapore Asahi Chemical & Solder Ind. Pte Ltd Asahi Lifecare Technology
Additional layers of protection are needed to protect the
most vulnerable

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Antimicrobial Coating Solution - Singapore Asahi Chemical & Solder Ind. Pte Ltd Asahi Lifecare Technology
AHC Anti-microbial Coating
       Technology

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Antimicrobial Coating Solution - Singapore Asahi Chemical & Solder Ind. Pte Ltd Asahi Lifecare Technology
Asahi Coating Technology Overview
                                           ✓ Suitable* for Glass, Wood, Fabric,           *Different substrates have different
                                             Textile, Leather (natural & synthetic),      adhesion and curing time, and surface
                                                                                          pre-treatment before coating
                                             Polymer, Metals

✓ Matrix + Additives + Diluent
✓ Specially formulated matrix                         Substrates
  for tunable concentration                                                           ✓ 99.99% anti-bacterial efficacy against
  and functions                                                                         E.coli (ATCC 8739), S.aureus (ATCC
✓ Silver/Copper Nanowires                                                  Anti-        6538P), MRSA and others.
  and/or Silver-ion based           Formulation                         Microbial     ✓ >99.99% against EV-A71 virus, H1N1
  additives for enhanced
                                                                       Performance    ✓ >99.99% Murine Coronavirus
  antimicrobial function                                                              ✓ >99.9% Surrogate COVID OC43
                                                        AHC
                                                       Binder
                                                                                       ✓ Non-cytotoxic (in-vitro)
   ✓   Tacky dried in minutes         Coating
                                                                           Safety
                                                                                       ✓ Non-skin irritation/ sensitization
   ✓   Thermal cure preferred
                                      Process                                            (according to ISO10993-10)
   ✓   Ambient cure suitable                                                           ✓ Food Contact (FDA Part 175.300)
   ✓   Suitable for spraying,                         Additional
       dipping, brushing,                             Functions
       wipe-on                                                         ✓   Hydrophobic
                              ✓   Transparent                          ✓   Stain Repellent
                              ✓   Colored tunable                      ✓   Protective coating
                              ✓   Gloss/ Matt finish tunable           ✓   Easy to Clean
                              ✓   Retain original look of Surfaces

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Antimicrobial Coating Solution - Singapore Asahi Chemical & Solder Ind. Pte Ltd Asahi Lifecare Technology
Disinfectant versus Antimicrobial
coating                                                                                            https://www.freepik.com/photos/technology>Technology
                                                                                                   photo created by freepik - www.freepik.com

  Disinfectant                                                               Antimicrobial Coating
  1. Ability to kill instantly                                               1. Effective control of bacteria, mould,
  2. Not sustainable                                                             fungi and viruses
  3. Require continuous application                                          2. Formation of transparent coating
       to get best effect                                                        onto surfaces
  4. Upon cleaning, efficacy is                                              3. Protective coating on existing
       compromised                                                               surfaces
                                                                             4. Withstand cleaning without losing
                                                                                 efficacy
                                                                             5. Absence of toxic effects on treated
                                                                                 surfaces
                                                                             6. Enhanced durability
                                                                             7. Continuously inactivate bacteria
  https://www.freepik.com/photos/health'>Health photo created by                 and viruses
  aleksandarlittlewolf - www.freepik.com
                                                                   KH Chew   Nov 2021

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Antimicrobial Coating Solution - Singapore Asahi Chemical & Solder Ind. Pte Ltd Asahi Lifecare Technology
Antimicrobial Coating
 Recommended Test Process and
 Procedures
Testing Procedure

   I.     Cleanliness Test By Adenosine Triphosphate (ATP) Method (Optional)
          a. Equipment Used (by Asahi Lifecare) is Kikkoman ATP Tester
          b. Take the cotton swab out from the individual casing provided by the supplier.
          c. Prewet it in the DI or Distilled Water.
          d. Rub the swab on intended test surface (100cm2) by following horizontal
             strokes and followed by vertical strokes.
          e. Placed the cotton swab back to the designated casing till you hear a click
             sound.
          f. Shake the casing vigorously till the chemical is in the casing dissolved
             completely.
          g. Placed the casing into the reader and READ and record results.

   II.    On Site Microbes Swab Test (In-House or 3rd Party Lab)
          a. Pre-wet the sterile swab stick in 0.85% sterile saline
          b. Rub the stick on intended test surface (100cm2) by following horizontal
             strokes, followed by vertical strokes
          c. After sampling, store the swabbed stick back to empty swab packaging
          d. Label the name of the intended surface and date and time of the swab
          e. Transport and store the swabbed stick to intended laboratory within 4 hours
          f. Report Results by laboratories with photos of the colonies.

Schedule of Swab Test
   1. Swab Test should be done before coating
   2. Swab Test done after 24 hours of coating or recommended by the coating supplier
                                                                  KH Chew   Nov 2021
   3. Scheduled swab as per intended timing after coating for example    swab every weekly
      or fortnightly or monthly to check on the coating efficacy towards microbes.
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Product and Application Video
(Youtube links)
        AHC7 Product Video

                                                  Nostalgia Hotel Project Video

                             KH Chew   Nov 2021

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Safety Tests

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Cytotoxicity Test
Report
Degree of cytotoxicity
Skin Irritation Test
Primary irritation is negligible (index
Skin Sensitization
Test Report
No skin sensitization, as per ISO 10993-10:2013
Biological evaluation of medical devices Part 10:
Tests for irritation and skin sensitization

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Food
Contact
Test

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Anti-bacterial Test Report

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Coated PET film with Antimicrobial activity value,
tested as per JIS Z 2801: Antibacterial Products -- Test For Antibacterial Activity And
Efficacy

  Conclusion: AHC7 has exhibited at least 99.99% reduction on various bacteria such as Staphylcoccus, MRSA, E-Coli,
  Kiensiella pneumonia, etc
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Coated fabric Undergo washability Test,
 tested as per ASTM E2180 - 07: Standard Test Method for Determining the Activity of
Incorporated Antimicrobial Agent(s) In Polymeric or HydrophobicMaterials

Conclusion: After 10X wash, coated fabric with AHC7 antimicrobial coating exhibited at least 99.9% reduction on
bacteria such as Staphylcoccus and Kiebsiella pneumonia.
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Anti-Virus Test Report

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Anti Viral Test Report using AHC coating

Conclusion:
AHC7 has showed complete
inhibition on influenza A virus or
H1N1

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Anti Viral Test Report using AHC coating

 Conclusion:
 AHC7 has exhibited at least
 99.99% reduction on EV-A71 or
 HFMD virus

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Anti Viral Test Report using AHC coating

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Test Results on
Sars-Cov2
Surrogate OC43
by TUV NORD

Conclusion: Efficacy against
Human coronavirus OC43
Surrogate to Sars-Cov2 99.9%

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Anti-Bacterial
Varying Contact
 Time Testing

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Conclusion: After 30minutes of coating, bacterial efficacy can be as much as 99.9%

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Washability Test

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Methodology
Adopted from ASTM D4828 - Standard Test Methods for Practical Washability
of Organic Coatings

• Check WCA & other properties of sample before
  test
• Soak the 3M sponge sufficiently with tap water
• Place the wet sponge and holder at one end of the
  panel so that its long axis is parallel to the length of
  the sample
• Turn on pump to add water while the equipment
  run
• Allow the sponge to travel specific number of cycles
• Check WCA & other properties of sample after
  specific number of cycles
• Test pieces were sent for Mueller Hinston Agar
  (MHA) Plate Testing using E-Coli BL21 in accordance
  to JIS Z 2801:2010 “Antibacterial products-Test for                Speed: 37±1 cycle/min
  antibacterial activity and efficacy”                           Load: Dry sponge + holder = 1kg
• Incubation period – 24 hours                KH Chew Nov 2021

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Bacterial Efficacy based Percent reduction after
24 Hours Contact
Sample condition:
- Sprayed 2 pass at 5cm distance – about 1 micron thickness
- Contact period: 24hours
- Incubation period: 24 hours

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Bacterial Efficacy based Percent reduction after 24Hours
Contact

Sample condition:
- Sprayed 2 pass at 5cm distance – about 1 micron thickness
- Contact period: 24hours
- Incubation period: 24 hours

                          Initial                        After 5k wash

AHC on PC                 >99% reduction                 > 99% reduction

AHC on glass              > 99% reduction                > 90%

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Examples of
AHC7/AHC23 End-Users

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The Mills International

• Anti-microbial carpets & flooring alternatives for exhibition halls

• Created a new line of product: EXPOflor

    Source: https://expoflor.com.sg/                                         Source: https://expoflor.com.sg/

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Nostalgia Hotel Singapore

• Boutique Hotel situated at Tiong Bahru

• Coated AHC7 for their hotel room, including
  curtains, carpet, bathroom

• Other high touch areas coated includes phone,
  remote control, switches and doorknobs

                                                  Source: https://www.hotelnostalgia.com.sg/

     Source: https://www.hotelnostalgia.com.sg/
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Thank you
KH Chew
Technical cum R&D Director

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