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INSPIRING BEST PRACTICE
IN MEDICAL AESTHETICS
AGED TO PERFECTION...
Sponsored by
INSIDE OUT
NAVIGATING PATIENT EXPECTATIONS
Septembet-October 2020 | aestheticmed.in
SMOKE SCREENING
MANAGING LASER PLUME
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INSPIRING BEST PRACTICE
IN MEDICAL AESTHETICS
AGED TO PERFECTION...
Sponsored by
SEPTEMBER-OCTOBER 2020
INSIDE OUT
NAVIGATING PATIENTEXPECTATIONS
Septembet-October 2020 | aestheticmed.in
SMOKE SCREENING
MANAGING LASER PLUME
Managing Director and Publisher
Vikas Vij
E: vikas.vij@ideas-exchange.in
T: +91 22 6171 3201
Executive Editor NEWS AND ANALYSIS COVER FEATURE
Shriyal Sethumadhavan 8 10 INDUSTRY NEWS 14 AGED TO PERFECTION
E: shriyal.s@ideas-exchange.in The latest news from What treatments are
M: +91 9820841355 the industry. trending for ageing skin?
Dermatologists share
Consulting Editor
Kanishka Ramchandani 08 PROMOTIONAL popular picks in recent
E: kanishka@wordmonk.in FEATURE months, commonly used
M: +91 9619544787 The HIFU revolution in devices, and their clientele
anti-ageing. approach to determine the
Finance Director ideal treatment.
Sharmila Pandey
E: sharmila.pandey@ideas-exchange.in
M: +91 9987588439 SKIN/DERMATOLOGY
Design 20 THE ANTI-AGEING
Arun Shirishkar
10 APPROACH
E: arun.shirishkar@ideas-exchange.in Skin appearance and
T: +91 9867989199 characteristics change with
ageing of body. Dr Sudhavani
Advertising Damarla, elaborates on ageing,
Aakash Chaudhary people’s perspective around it
E: aakash.chaudhary@ideas-exchange.in
M: +91 9820444705 and treatment options.
Marketing 24 TIPS TO SKIN HYDRATION!
Khyati Mishra Gone are the days when
E: khyati.mishra@ideas-exchange.in moisturizers were meant for
M: +91 9769281874 people with dry, flaky skin.
Operations Moisturizers should be an
Priyanka Parshurami integral step in skincare
E: priyanka.parshurami@ideas-exchange.in routine. Here's some of our top
M: +91 9833472397 20 moisturizer picks that can be
recommended to drench skin
Circulation – Subscription & Database in moisture.
Shahnawaz Ansari
E: ansari.shahnawaz@ideas-exchange.in
T: +91 22 61713232
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4 Aesthetic Medicine • September-October 2020
CONTENTS
www.aestheticmed.in IN THIS ISSUE...
29 35 47 47 57
26 INSIDE OUT F E ATU R E DEVICES BUSINESS 50 HEAD SPACE
Anti-ageing might be one 35 SMOKE SCREENING 42 IN THE KNOW 47 STRONG START We explore how to safeguard
of the latest buzzwords Dr British Medical Laser Aesthetic Medicine Dr Sadaf Hussain and Dr your own mental wellbeing as
in aesthetic dermatology Association honorary explores the market Simon Zokaie you return to your aesthetic
but there is more to it than secretary Jon Exley on growth, features select answer some of the most practice.
meets the eye. managing the risks devices and delves pressing questions for
associated with covid-19 into the technological newly-qualified practitioners. 54 IN FOCUS
29 BODY IS THE during aesthetic laser advancements The virtual consultations may
NEW FACE procedures that coming along. 57 STRATEGY FOR make good business sense,but
Dr Jamuna Pai shares more create plume. SUCCESS there’s more to consider.
on trending treatments and PR expert Julia Kendrick
modalities, and her book on 39 PATH TO RECOVERY outlines why a PR strategy is 59 NEW LAUNCHES
anti-ageing. POST-SURGERY so important when it
Here's listing some comes to making SEO 61 EVENTS CALENDAR
CLINICAL nutrients and food that are marketing support your
31 RESTORATION essential to take care of aesthetic business. 62 AM INDIA VIRTUAL EVENT
PROJECT post a cosmetic surgery.
Dr Timothy Eldridge shares
65 OUT AND ABOUT
the journey of a 57-year-old
woman undergoing facial
aesthetics for the
first time.
Welcome to the
56 September-October 2020
issue of
Aesthetic Medicine magazine
Dear Reader
Age is just a number, and you are just as old as you feel. If we agree, then why not bring new
life to the skin, and give it the appearance that matches the mental age? Well, I may have many
supporters on this one. Convincingly, market numbers reveal so: A steep rise in the demand
for anti-ageing treatments over the last five years, owing to which, its device market in India has
grown multi-fold in the last decade and is expected to witness steady growth in future.
This edition features much about anti-ageing treatments. For most recommended treatments, turn
to page 14; more on page 20 for people’s perspective towards ageing and treatment options; for
technological advancements, page 42; and to understand how to navigate patient expectations
and ensure maximum satisfaction, our story on page 26.
This plus, some global insights on managing risks associated with COVID-19 during
aesthetic laser procedures that create plume (Pg 35). Also, do read the inspiring journey
of a 57-year-old woman undergoing facial aesthetics for the first time (Pg 31).
It would be great to have your feedback on this edition. Do write in to
shriyal.s@ideas-exchange.in
Wishing you safe times ahead!
Shriyal Sethumadhavan
Executive Editor
Aesthetic Medicine • September-October 2020 5
E D I TO R I A L B OA R D
www.aestheticmed.in
O U R E X P E RT S
CLINICAL EXPERTISE
The Aesthetic Medicine editorial board
includes some of the leading names in
aesthetics. Their clinical expertise and
diverse range of specialties will help
ensure the magazine meets the needs
of its readers.
Dr Shailesh Vadodaria:
Consultant Aesthetic and
Reconstructive Plastic CALL FOR ARTICLES
Surgeon; on the Specialist
Register of the General
Medical Council, UK;
practices from the Clementine Churchill BMI
Hospital, Harley Street, and Medical Arts for
Cosmetic Surgery Clinic (MACS) in Watford,
North London
Dr Lakshyajit D Dhami:
Cosmetic, Plastic and
Laser Surgeon; Consultant
Cosmetic and Plastic
Surgeon at Nanavati and
Hinduja Hospitals; Founder of
Vasudhan Arjin Cosmetic & Laser
Surgery Centre, Mumbai; and President of
Indian Association of Aesthetic Plastic
Surgeons (IAAPS)
Dr Amit Luthra:
Cosmetologist and
Dermatologist; Heads Ishira
Skin 'N' Child Clinic, New
Delhi; Member of European
Academy of Dermatology
and Venereology (EADV),Indian Association
of Dermatologists, Venereologists and
Leprologists (IADVL), and Cosmetology
Society of India (CDSI)
Dr Neeta Patel:
Plastic, Cosmetic and Are you interested in
Reconstructive Surgeon,
Mumbai; and past President of
Indian Association of Aesthetic
becoming a contributor
Plastic Surgeons (IAAPS) to Aesthetic Medicine
Dr Mukta Sachdev:
Head of Department and
magazine?
Consultant
Dermatologist, Manipal Do you have articles you would like to
Hospital, Bangalore; Director,
M S Skin Centre, Bangalore
write or any thoughts, treatment tips or
techniques you would like to share? Then
Dr Parag Telang: we would want to hear from you.
Director at Designer Bodyz
Centre for Advanced Whether it’s writing about running an
Cosmetic Surgery, Mumbai; aesthetics business or sharing your case
Consultant Cosmetic and
Reconstructive Plastic
studies and clinical expertise, you can get in
Surgeon; and Specialist in autologous ear touch with us with your ideas.
reconstruction, Minimal Incision Face-lift
(MACS-Lift) and ultrasonic liposuction
Dr Apratim Goel: Email: ameditgroup@gmail.com
Senior Cosmetic
Dermatologist and
Venereologist; CEO and
Medical Director of Cutis Skin
Studio, Mumbai/; Fellow of
Academy of General Education (FAGE); and past
President of Association of Facial Aestheticians
and Aesthetic Surgeons of India (AFAASI) www.aestheticmed.in
6 Aesthetic Medicine • September-October 2020
P R O M O T I O N A L F E AT U R E
www.aestheticmed.in
The revolutionary
HIFU in anti-ageing
Doublo-Gold is a time tested & trusted brand over last nine years across the globe.
It is largest preferred brand among all HIFU devices, over 700,000 treatments have
been performed successfully with 4,000 installed systems of Doublo series. Doublo-
Gold is setting new standards as an advanced HIFU technology with 25 registered
patents and fastest treatment by Two-way round shoots. Here’s what skin experts
have to say about the device.
D
oublo Gold is the latest generation of High the next 12-14 months.
Intensity Focused Ultrasound (HIFU) technology More specifically, the Doublo Gold lifting treatment
from Hironic, the pioneer of HIFU in Korea. It has reduced the treatment time for 300 shots from 16
delivers focused thermal energy through the minutes to 8 minutes as compared to existing devices.
skin layers, safely reaching the SMAS to promote Additional features such as continuous shots and shot
collagen regeneration. interval adjustment provide a more convenient and
So far, several lifting methods have been developed satisfactory treatment.
such as fillers and thread
lifting. However, Doublo
lifting has been receiving
more attention because it is
a simple procedure without
any downtime. Thanks to
its superior results, clinical
studies have proved high
customer satisfaction. In
India, many clinics are
much pleased to offer this
novel cosmetic procedure to
their patients.
Doublo Gold uses HIFU
energy to penetrate under
3.0~4.5 mm of dermis layer and
SMAS layer without damaging
the superficial layer and
creates a thermocoagulation
zone (TCZ) smaller than 1 mm.
TCZ helps to contract the
sagging skin tissue and lifts
up the skin. Over one to three
months, elastin and collagen
are produced to maintain the
lifting effect, which last for
8 Aesthetic Medicine • September-October 2020
P R O M O T I O N A L F E AT U R E
www.aestheticmed.in
WHAT SKIN EXPERTS HAVE TO SAY ABOUT DOUBLO-GOLD:
Dr Rickson Pereira, Dermatherapie Clinic, Mumbai, says, “Doublo-Gold focused ultrasound
is a promising treatment that offers remarkable results in skin tightening and rejuvenation,
non-invasive facelift, jowl reduction, jawline and neck tightening and much more. My
patients are extremely satisfied with the transformation it has brought in. Doublo Gold is
an advanced version of the previously successful Doublo-S. Like its predecessor, I am sure it
will revolutionise anti-ageing treatments.”
Dr Ishad Aggarwal, Wizderm Speciality Skin & Hair Clinic, Kolkata, says, “Doublo Gold has
become a premium treatment in my clinic, thanks to the high-end technology that offers these
outstanding results. Being a non-invasive one, it is comfortable for my patients and does not
demand any major downtime. This novel cosmetic tool effectively rejuvenates the deep layers
of the skin, delivering innovative HIFU energy to the targeted tissues and creating selective
thermal coagulative zones in the subcutaneous layer or superficial musculoaponeurotic
system (SMAS) at 3 mm and 4.5 mm, without the risk of damage to the superficial skin or surrounding tissues. The
treatment results in significant tightening and lifting of the targeted tissues, as well as improved contours of the
treated areas.”
As Dr Ginni Chhabria, Skinology Center, Indore, shares, “If you are practising anti-aging, the
Doublo-S device should be there at your clinic. It is a non-invasive technology, which gives a
desirable facelift. Jaw line contour is amazing. There is no downtime. Me and my clients we
both are happy.
Dr Datta S S, Director, La Peau Laser World & Skin Clinic, Thane, Navi Mumbai, says,
“Doublo Gold HIFU is the best-in-class device for face and body contouring. It is the fastest
in its category. I have been using this device for the last two years and it gives excellent
results to satisfy patients. It is not only doctor-friendly but also patient-friendly. It has got
advantages over other technologies as single sitting treatment with zero downtime as well
as prolonged treatment effect.”
According to Dr Rupali Pavaskar, Transforme Cosmetic Center, Thane, Navi Mumbai, “I was
overwhelmed with my own experience after taking Doublo Gold treatment for the first time.
It showed prominent improvement and that too without any downtime. A large majority
of my patients are satisfied with the aesthetic outcomes and improvements achieved
in the signs of skin ageing. I could work on deep skin structures of 4.5 mm of SMAS area,
simultaneously target deep dermis with 3 mm for effective fibroblast activation and collagen regeneration and
address other aesthetic indications such as body shaping.”
Dr MK Shetty, Dr Shetty’s Aesthetics, Bengaluru, says, “I have been using Doublo-S focused
ultrasound technology for about three years in my practice with assured results without
any complications. This specific device offers you different cartridges for different level for
facial lifting and body contouring.”
Aesthetic Medicine • September-October 2020 9
N E W S A N D A N A LY S I S
INDUSTRY NEWS www.aestheticmed.in
Light therapy market expected to exceed US$ 1 billion by 2025
As per the market research report, the light therapy expected to observe sharp growth by 2025. Psoriasis, a
market is expected to exceed US$ 1 billion by 2025 with chronic skin condition caused by the overactive immune
red light therapy treatment witnessing a CAGR of over 4.5 system along with red patches, inflammation and flaking,
per cent. The growing adoption of light therapy in various has accounted for more than 20 per cent revenue share in
medical conditions will further accelerate the demand for 2018 and is believed to witness substantial growth in the
light therapy devices thereby augmenting business growth. coming years.
Increasing demand for non-invasive skin treatment such as Due to the increasing prevalence of dermatological
blue light therapy for treating skin diseases including acne diseases coupled with the growing demand for aesthetic
vulgaris will favour the growth of the light therapy market. procedures, the Asia Pacific region is estimated to exceed
However, several side effects of light therapy including US$ 250 million by 2025. Moreover, sustainable economic
headache and nausea may hamper future industry growth. growth and rising healthcare expenditure in countries such
Light visors segment, which accounted for around US$ as India, China and Japan will further accelerate the regional
79 million, and the dermatology clinics segment, which light therapy market growth.
accounted for about US$ 210 million in 2018, are also
Market valuation of botulinum toxin expected to cross US$ 8.9 billion
by 2026
Increasing adoption of minimally invasive
surgeries or non-invasive procedures is expected
to drive the botulinum toxin market to US$ 8.9
billion by 2026. Botulinum toxin is used in facial
injectables, which are the most frequently
performed procedures in western countries. It is
divided into two segments: Botulinum toxin A and
botulinum toxin B. The ‘A’ segment, which is widely
used for treating forehead lines and square jaws,
is expected to grow at 8.9 per cent from 2020-
2026. Moreover, a rise in demand for botulinum
toxin A to treat muscle spasm is likely to drive
segment growth. Due to the growing demand for
skin rejuvenation and surgeries among middle-
aged women, the female segment is projected to
register a CAGR of around 8.8 per cent through
2026 as botulinum toxin A is leading in this
procedure.
As predicted, the botulinum toxin market in the
APAC region is set to witness significant growth by
2026. High growth rate is attributed to the ageing
population, and a subsequent increase in demand.
Growing adoption of botulinum toxin products,
rising social awareness, and accessibility to new
technologies and products is another reason for
augmenting market growth.
Dermalogica PROSKIN Masters 2020
Dermalogica India is all set to launch PROSKIN Masters line with the new changed environment. The competition
2020, one of the biggest skill competitions for professional provides the perfect platform for the therapists to
skin therapists. The competition aims to test the knowledge, showcase their expertise and gain widespread recognition
skill, and expertise of the professional skin therapists – and for themselves and their salon, in the industry as well as
celebrate the transformations they bring into the lives of the among end consumers.
customers through their work, every day. Dermalogica trains The, PROSKIN Masters 2020, will be judged by the best in
more than 100,000 experts across 120 countries every year. the industry along with Dermalogica Global Educator Angela
The competition is open to all Dermalogica certified Taylor.
therapists across the country. It will test their theoretical For more information, visit Dermalogica India’s Facebook
knowledge as well as the skill in consultation, understanding page or interested participants can register on: https://
the consumer’s problems and the actual service delivery in forms.gle/CACzVQGnsijA4H879
10 Aesthetic Medicine • September-October 2020N E W S A N D A N A LY S I S
www.aestheticmed.in INDUSTRY NEWS
Aesthetic devices market is expected to NEWS IN BRIEF
reach US$ 6,620 million by 2024
Global studies indicate that the aesthetic devices market is expected to SURGE IN THE GLOBAL
HOMECARE DERMATOLOGY
grow at a CAGR of roughly 5.3 per cent and reach US$ 6,620 million by 2024 as ENERGY-BASED DEVICES
compared to US$ 4,870 million in 2019. In recent times, with the rise in spending MARKET
capacity and the proportion of people taking on medical treatment and aesthetic The homecare dermatology energy-
treatment, aesthetic devices have become more and more popular. The market based devices – including laser
equipment that are widely used
is growing fast as the focus has been more on beautification. Although the for removing skin pigments, hair,
market scale is still limited at present, the potential is considerable. The wrinkles, and acne – has observed a
aesthetic devices market is consolidated in nature. Various players are adopting surge in recent times. Easily available
competitive strategies such as collaborations, acquisitions, and capitalising on the counter, these devices are
becoming immensely popular among
untapped opportunities in the emerging economies of India and China, to sustain the masses. As a result, people who
and gain market penetration across the globe. want to undergo minor dermatological
A report by 360 Research points out to the US as the largest market for treatments need not undergo heavy
aesthetic devices with 36.12 per cent of global aesthetic devices procedures procedures with the use of such
equipment. Constant technological
per year followed by Europe and China with 35 per cent of the global industry, and research advancements in the field
respectively. Other prominent regions in this industry include the Middle East of dermatology and cosmetics have
and South America. played a significant role in spreading
the reach of the global homecare
dermatology energy-based devices
Global dermatology lasers market to register market. The APAC region is expected
to exhibit a strong CAGR in the coming
a CAGR of over 14 per cent by 2023 years. With emerging economies such
as India and China that are spending to
The growing demand for laser treatment, develop their healthcare infrastructure,
the homecare dermatology energy-
including laser skin resurfacing and tightening
based devices market is expected to
among the middle-aged population, is witness ample business opportunities.
encouraging more end-users to offer laser
treatment. As a result, the global dermatology GLOBAL DERMABRASION
laser market is expected to register a growth of MARKET IS EXPECTED TO
GROW WITH A CAGR OF 4.82
over 14 per cent CAGR by 2023. Laser treatment PER CENT BY 2025
is a highly costly and expensive treatment as it Global market reports indicate that due
involves a lot of equipment for its maintenance, to an increase in demand for advanced
and materials such as cooling gels and numbing skincare treatment options, rising
number of skin disease patients and
creams. All this together adds up to the treatment growing emphasis on dermatology,
cost. the global dermabrasion market is
Due to the growing awareness about cosmetic procedures among the individuals expected to grow at a CAGR of 4.82
who are becoming more consciousness about beauty and their appearance and aware per cent by 2025. It is frequently used
for facial procedures that are carried
of cosmetic procedures, such procedures are gaining importance among individuals out with the use of wire brush or a
who want to restore or enhance their natural beauty. Moreover, the availability of diamond wheel with stony edges to
cosmetologists with advanced knowledge about new laser techniques in cosmetic eliminate and level the upper layer of
dermatology treatments has increased the market growth. the skin. The treated area heals and
allows new skin to grow in its place.
Rising number of skin disease patients,
increasing importance of dermatology,
Global aesthetics combination therapy mar- and the increasing demand for
advanced skincare treatment are
ket projected to grow at 8.1 per cent CAGR the major factors driving market for
dermabrasion. Growing interest for
According to Persistence Market Research report, the global aesthetics healthy skin treatment choices and the
combination therapy market, valued at US$ 1.97 billion in 2016, is estimated to reach developing prominence on dermatology
US$ 3.69 billion, at a growth rate of 8.1 per cent CAGR from 2016-2024. The market is are also gradually supplementing the
segregated into three types: Therapy, applications and end-use. Under therapy, the market growth.
BTx-A/dermal filler the most pursued therapy is projected to grow at 10.9 per cent BODY MODIFICATION, AND
CAGR by 2024 whereas BTx-A/laser – second largest segment in terms of revenues HOW!
– is projected to grow at 6.6 per cent CAGR by 2024. As per the global trends and Sandro from Finsterwalde, Germany, has
reports, aesthetics combination therapy is expected to witness strong growth in spent Rs 5.8 lakh on body modification
over the last 13 years. This 39-year-
hair removal and tattoo removal procedures. The third segment of end-use, is further old man has undergone 17 procedures
divided into three parts: Hospitals, ambulatory surgical centres, and dermatology of body modifications, the recent one
clinics. Of these, dermatology clinics are anticipated to grow at a CAGR of 10.7 per being removing both the ears and
cent by 2024. keeping them in a jar. Reportedly, in the
past, he has also had implantations in his
Marketwise North America and Europe continue to be the largest markets for forehead, forearms, and the back of his
aesthetics combination therapy market, wherein North America is expected to hold hand. Sandro has reportedly mentioned
41.3 per cent revenue share by 2024 as compared to 2016 and remain the largest that these body transformations over
market by revenue holder. Similarly, in Europe, France is projected to witness the the past years have strengthened his
self-confidence.
second highest CAGR by 2024 with Italy leading the region.
Aesthetic Medicine • September-October 2020 11N E W S A N D A N A LY S I S
INDUSTRY NEWS www.aestheticmed.in
NEWS IN BRIEF Global photorejuvenation devices market to
reach US$ 2,521.1 million by 2025
As per a market research report,
the Global Photorejuvenation Devices
Market, which was valued at US$ 1,622.3
million in 2018 is expected to reach US$
2,521.1 million at a CAGR of 6.50 per cent
by 2025. Technological advancements
QR 8 THERAPY FOR HAIR in the field of rejuvenation technology
REGROWTH
As per the global report and a study can provide various opportunities for
published in the American Journal, the further market growth.
QR 678 therapy has proven to be more
effective than PRP as a hair loss treatment Photorejuvenation is a skin treatment
with almost 100 per cent reduction in hair that uses lasers, strong pulsed light,
fall. This new therapy curbs hair-fall and or photodynamic therapy to treat
increases the thickness, the number and
density of existing hair follicles, offering skin conditions and remove effects of
greater hair coverage, especially to the photo-aging such as wrinkles, spots, and
ones with alopecia. While PRP is supposed
textures. The use of photorejuvenation therapy is extensive and often used as
to have growth factors for hair growth,
the QR 678 treatment is a bioengineered, an alternative for expensive skin treatments such as plastic surgery. It is useful
a first-in-class hair therapy, with six hair in enhancing skin quality, removal of fine wrinkles from the facial skin, removal of
growth factors and biomimetic peptides,
administered to the scalp via mesotherapy. skin marks and spots, and some other treatments such as age spots, sunspots,
This non-surgical, pain-free, and non- and freckles.
invasive procedure for hair regrowth
treatment formulation has received
patents in the United States and in India. The global cosmetic laser market to
PLASTIC SURGERY MARKET TO expand at a CAGR of 13.7 per cent by 2026
REMAIN POSITIVE IN 2020
As per the report from the Persistence As per a report by Transparency Market Research, the global cosmetic laser
Market Research, a rising number of market which was valued US$ 1,455.1 million in 2017 is anticipated to expand
geriatric people along with the growing at a CAGR of 13.7 per cent from 2018-2026. This expansion can be attributed
demand for retaining young and beauty
is key driver for the global plastic to a rise in medical tourism among people to avail high-quality treatment at
surgery market, thus helping it remain affordable rates in the emerging economies of Asia Pacific and Latin America.
positive through 2020. Plastic surgery,
a part of cosmetic surgery, is used Further, continual growth of the cosmetic industry is projected to augment
for the restoration and enhancement the global cosmetic laser market between 2018 and 2026.
of the aesthetic appearance of an In terms of revenue, the cosmetic laser market in Asia Pacific is projected to
individual. North America and Europe
dominates the global plastic surgery expand at a CAGR of 14.1 per cent by 2026. An increase in awareness regarding
market, with Europe holding a major the advantages of minimally invasive cosmetic procedures, favourable
share. The market in Asia is expected government laws supporting medical tourism, attractive procedure rates, and
to show high growth rates in the next
five years due to increasing awareness rise in population in this region is expected to present attractive opportunities
about plastic surgery procedures and for the cosmetic laser market in the coming years.
the growing medical tourism industry.
China and India are expected to be
the fastest growing plastic surgery Global demand for derma fillers to increase
markets in Asia.
at a CAGR of 7.7 per cent by 2026
DERMATOLOGY DRUGS MARKET
EXPECTED TO REACH US$2. As per the global report, the global dermal filler market share is slated to
MILLION BY 202 amass substantial gains in the coming years owing to the global demand for
As per the report from Data Bridge
Market Research, the dermatology drugs dermal fillers exclusively in dermatological clinics and is expected to increase at
market is growing at a CAGR of 8.2 per a CAGR of 7.7 per cent from 2020-2026.
cent and is expected to reach US$27.66 High disposable income and a vast geriatric population in developed countries
million by 2027. Increasing prevalence
of skin diseases and growing awareness such as the US, Europe, and the UK is steering the use of advanced cosmetic
for diagnostics and treatment of skin procedures with an aim to improve the skin texture. Developments in dermal
diseases is the major driver for market filler mechanisms provide improved facial contouring and wrinkle treatment
growth. Dermatology drugs are raising
awareness about the treatment of skin end results.
related diseases such as acne, alopecia, In 2019, the India dermal filler market was responsible for over 14 per cent
cutaneous mastocytosis, dermal necrosis
and dermal ulcer which will accelerate the of the revenue share of the entire Asia Pacific dermal filler industry. Skincare
market growth. Extensive R&D activities clinics are extensively being established in developing countries like Argentina,
in dermatology drugs will further create China, Japan, Korea, and India. They provide specific, targeted services to the
new opportunities and impact the
dermatology drugs market growth in the customers in a short period of time and play a crucial role in steering the demand
forecast period 2020-2027. for soft tissue fillers in these settings among the consumers. AM
12 Aesthetic Medicine • September-October 2020IRELAND
EVENTCITY MANCHESTER
14 NOVEMBER 2020
RECONNECT
with the industry
REUNITE
at a new venue
REGISTER
to join the community
Register for free at www.aestheticmed.co.uk/north2020
/aestheticmedicinelive @aestheticmed_live @AestheticMLive
#AMNorthCOV E R F E AT U R E
ANTI-AGEING www.aestheticmed.in
Sponsored by
T Aged to
he cliché “what is old is new again,” is a suitable
anecdote for the ageing urban Indian population.
The ageing population wants to bring new life to
Perfection
their skin and give it the appearance that matches
their mental age and not chronological age.
“The shift in attitude of people has prompted the growth of
anti-ageing treatments to reverse
the signs of extrinsic and intrinsic
ageing,” says Dr Chiranjiv Chhabra,
What treatments are trending for ageing
Founder Director and Chief skin? Shriyal Sethumadhavan
Dermatologist, Alive Wellness connects with dermatologists to
Clinics. She shares the following
statistics from 2019 that depict the
understand popular picks in recent
age distribution of India: 26.6 per months, commonly used devices, and
cent = 0 to 14 years; 67 per cent = 15 to 64 years; and 6.38 per their clientele approach to determine the
cent = 65 years and above.
“Anti-ageing treatments have
ideal treatment.
always been in demand but now
the awareness is more among the clients consulting dermatologists and aesthetics clinics is
millennials who want to invest increasing.
in preventive procedures over In terms of the trending age group that opts for this
curative,” says Dr Sonia Tekchandani, treatment, it is known that most people start at their
Consultant Dermatologist, Tender early 30s. Dr Rasya Dixit, Medical Director, Dr Dixit
Skin International-India and UAE. Cosmetic Dermatology, brackets the age group between
“The demand for anti-ageing procedures has increased over 30-60-year-old. On his part, Dr
the last 10 years,” says Dr Shefali Rishi Parashar, Senior Consultant
Trasi Nerurkar, MD Skin, Consultant Dermatologist, Sir Ganga Ram
Dermatologist, Dr Trasi’s Clinic & hospital, New Delhi, and Parashar
La Piel. “What was considered as an skin clinic, New Delhi, witnesses
accessory treatment is now one of maximum demand from those aged
the essential parts for a lot of the 40-50 years. For Dr Chhabra, its
patients.” Dr Rasya Dixit 35-50-year-old, and she mentions,
In agreement, Dr Padmavathi “Recently, we are seeing the range starting from 24 years.”
Surapaneni, Dermatologist, Pragna Skin and Laser Clinic, On similar lines, Dr Tekchandani,
Hyderabad, also adds that there adds, “Maximum demand of anti-
has been a steep rise in the last five ageing treatments earlier was
years. She says, “While we have seen upwards of 40-45+ age group.
more women than men opt for this However, we have noticed an
treatment, demand from men has upsurge in the 25-30 age bracket in
also seen a rise in the last the last few years.” She attributes
three years.” this increase in awareness to the
Dr Chhabra too agrees that a selfie fad, and the need to look your Dr Rishi Parashar
market shift has been observed and the percentage of male best always to maintain a social profile.
14 Aesthetic Medicine • September-October 2020COV E R F E AT U R E
www.aestheticmed.in ANTI-AGEING
HOW DO YOU APPROACH YOUR CLIENT?
To determine the ideal anti-ageing treatment for the client, what are the key questions with which they can be approached
during consultation?
“The basic question would be first to know what their major concern area is, and why?” says Dr Sonia Tekchandani,
Consultant Dermatologist, Tender Skin International – India and UAE. She adds, “Also understanding their timelines and
debriefing them on the duration required for these treatments to deliver optimum results. If this is their first time trying
these treatments, we prefer taking it slow, so they get some to process how these treatments work.”
Dr Chiranjiv Chhabra, Founder Director and Chief Dermatologist, Alive Wellness Clinics, highlights, “Patients approach
aesthetic services with the hope that they will achieve their desired results.” She suggests, “The objective of the aesthetic
consult is to display your knowledge, professionalism, and trustworthiness. Explore the patient’s goals, motivations, and
expectations within a relationship of trust. Ask questions focussed on the patient’s concerns, preferences, desires, and
values. And, genuinely help them to prioritise their needs and get started.”
DEMAND IN THE COVID-19 ERA WHAT’S TRENDING!
The pandemic era has certainly had its own impact on Treatments for anti-ageing include MNRF, radiofrequency
patient inflow. for skin rejuvenation and tightening, anti-ageing medi-facials,
“The number of patients opting for anti-ageing collagen boosting procedure, botulinum toxin, dermal fillers,
treatments declined to one third,” says Dr Surapaneni. She hydrating fillers, and thread-lift. Among these, injectables,
further adds that demand for injectables were affected and botulinum toxin and dermal fillers always are the mainstay of
dropped to one third. Demand continues for energy-based anti-ageing therapies for skin textural improvement.
therapies such as radiofrequency and HIFU. “As compared But which treatments have been trending in recent months?
to pre-COIVD, I can see an increased demand for fractional For Dr Dixit, its botulinum toxin, fillers, and threads. Dr
resurfacing, as clients who cannot withstand the downtime Parashar mentions chemical peels, HIFU, botulinum toxin,
because of their busy schedule are planning now.” platelet rich plasma (PRP), and microneedling RF. While Dr
On her part, Dr Nerurkar shares, “Post-COVID, definitely Nerurkar sees an increase in number for anti-ageing treatments
the response has gone down. Patients want to do the such as botulinum toxin injections, fillers and body contouring;
treatments but are scared to venture out to clinics and Dr Tekchandani highlights the most popular ones at her clinics
get the treatment done. However, once they are convinced – “the sought-after Kim Kardashian fame vampire facial or
about the safety measures taken in clinic, they are more collagen induction therapy as we call it.”
forthcoming and start with the treatments.” She further One of the most popular and effective anti-ageing therapies
categories the patients into two types these days. “In some is radiofrequency skin tightening, points out Dr Surapaneni.
patients, because they are sitting at home with not much “HIFU for skin tightening and lifting has gained popularity in
socialising, they are ready for treatments with downtime. recent years and is well accepted by clients with good results.
And in some patients, due to the financial downfall, they Collagen induction therapies such as fractional lasers and
are avoiding any treatments till they earn the extra bucks to derma rollers are much used. The new entries are the PRP
spend on themselves.” therapy and skin boosters for reviving matured skin and
Dr Tekchandani shares her observation and experience improving collagen and elastin.”
here. “Immediately post-COVID unlock 1, the patient To this, Dr Chhabra shares, “The pandemic has changed the
response was immensely slow. Only a handful clients made way we look. Poeple are more oriented towards beauty, health,
it to the clinic because of the various curfews and the 2 km and fitness.” She adds that clients are coming in for:
rule. But with time, we have gone back to 70 per cent of our • Injectables: Clients are looking at quick fixes. They want
pre-COVID number of walk in’s. The senior clients, who are treatments that require less visits and deliver promising
60+, tend to still be a little apprehensive about stepping and long-lasting results. They are opting for fillers for
out. A good number of clients who were apprehensive rejuvenation, face-lift and contouring, and botulinum toxin for
about injectable procedures have come asking for it as getting rid for lines and wrinkles.
the pandemic has given them the time to evaluate the time • Hair reduction laser: People are coming regularly for their
spent on multiple sitting procedures over single sitting long body and face hair reduction. They are referring their
lasting results procedures.” friends and family as they have realised the comfort of long
While Dr Parashar agrees that there have been less hair-free periods.
procedures as this socioeconomic stratum is more • Laser treatments for skin rejuvenation and whitening.
conscious of their health, he adds that botulinum toxin • Non-surgical and minimally invasive anti-ageing treatments
is still coming along with chemical peels. Similarly, such as Ulthera and Thermage/Scarlet.
Dr Dixit mentions that people are now asking for creams and • Hair transplant: Since people are working from home, they
oral supplements, and are slowly coming back to want to do hair transplant that mostly involves shaving off
clinics for treatments. the head.
Aesthetic Medicine • September-October 2020 15COV E R F E AT U R E
ANTI-AGEING www.aestheticmed.in
a year to maintain the desired results. The end results are
tightening of skin lift of saggy tissue with reduction in the
jowls and nasolabial folds resulting in the most desired ‘‘v’
shape lift of face. Pain is the main issue for this procedure
when compared to other aesthetic procedures, but topical
anesthesia and analgesics help tackle this.
Botulinum toxin: Here is one of the most time-tested
procedures with high client satisfaction. “Botulinum toxin
is used to relax muscles, like frown lines, forehead worry
lines and crows feet. A session takes 20 to 30 minutes to
complete, and results are seen in a week,” says Dr Dixit.
Botulinum toxin injections are recommended by doctors
when you can see wrinkles on forehead, frown and around
the eyes, says Dr Nerurkar. Elaborating on the benefits,
she says, “It relaxes the overactive muscles causing these
wrinkles and makes the skin look rejuvenated. The diluted
form called microbotox can be done on the entire
face to tighten the face.”
Dr Tekchandani mentions, ‘facelift in
Injectables,
ANTI-AGEING TREATMENTS a bottle’ as we call it at Tender Skin is a
Aesthetic Medicine puts together botulinum toxin minimally invasive procedure. It helps
a consolidated lists of recommended and dermal fillers in relaxing the muscles while taking
anti-ageing treatments: always are the mainstay care of fine lines and wrinkles. And as
HIFU (High Intensity Focused Dr Surapaneni puts it, “The therapy
Ultrasound): Dr Nerurkar recommends
of anti-ageing therapies takes away few years from the face.
HIFU in patients for skin tightening. for skin textural It is injected targeting specific muscle
HIFU is ideal for patients whose skin is improvement. to relax them and reduce the expression
loose and saggy leading to heavy lower lines.” Botulinum toxin is also used to reduce
face and forms nasolabial folds and jowls. bunny lines and marionette lines, nefertiti neck
“HIFU waves can penetrate to deeper layers lift by relaxing platysma.
of skin called SMAS, the tightening of which, lifts the skin The most common side-effects include bruising, which
up,” says Dr Surapaneni. “Twenty per cent of the results settles in a week. Spread of toxin to adjust muscles can
are seen immediately and maximum lift is seen by two to cause weakness of that muscle for a couple of days. Side
three months.” effects such as ptosis is rarely witnessed if performed by an
The second session can be done after three months if experienced specialist. A big myth that needs busting is that
further tightening is required. This treatment is done once it gives you a frozen look. However, excess units of
TO LOOK AS GOOD AS I FEEL!
Cosmetic treatments have a major impact on the More acceptance: To self-improvement and self-care
confidence and self-image of an urban Indian. “We are a rituals, this is seen more in millennials. The GEN-X is
country of Generation-X and millennials. We have more also getting motivated from the millennials.
disposable income,” says Dr Chiranjiv Chhabra, Founder More affordability: Plastic surgery or aesthetic
Director and Chief Dermatologist, Alive Wellness Clinics. procedures are not limited to uber wealthy. More
She adds, “People do not want to wait for wrinkles to form double income families, flexibility for personal loans,
and are taking pre-emptive measures to maintain their credit cards and EMI options are present.
natural youthful appearance as long as they can.” While the More technological advances: We have lasers, which
preference is towards low risk, pain-free and non-invasive did not exist 10 years ago.
procedures over surgeries, Dr Chhabra highlights the major More health benefits: Aesthetic procedures improve
reasons for increase in aesthetic procedures: self-esteem for example procedures such as breast
Self judgement: We document ourselves more than reduction can reduce back ache. Aesthetic procedures
what our parents and grandparents did. We have our have great psychological benefits.
hundreds and thousands of selfies and pictures. We More self-confidence oriented urban Indians: The
keep judging our own appearance as well as our ageing urban Indian believes in more self-confidence.
process.
16 Aesthetic Medicine • September-October 2020COV E R F E AT U R E
www.aestheticmed.in ANTI-AGEING
botulinum injections can tighten the face leading to frozen to one year and with new fillers coming, results even
features and looks; the effect wanes out over a period of last longer up to 14-16 months. Minimal side-effects are
three to four weeks. possible like bruising or a lump like sensation in some
For this treatment, one sitting every six months is the areas which are easily addressed and manageable.
requirement, and once it is done, the results last for four to
six months. Botulinum toxin can be done to give your client Radiofrequency: This is a noninvasive procedure,
just the look they want, patient counseling is key here. which helps in building up collagen, resulting into an
instant tightening effect. As Dr Tekchandani shares, “It
PRP Therapy: PRP is a promising regenerative therapy is recommended to patients who are looking for a more
for ageing skin. It is commonly known as vampire facial or pampered treatment with a natural lift without injectables.
vampire face-lift. As Dr Surapaneni, says, “It leads to loose It requires about three sessions and a maintenance after
skin, wrinkles, fine lines and pigment formation, a every three months. The most loved aspect of the
decrease in collagen formation and reduction treatment is that it has no downtime or side-
of collagen.” Platelets are rich in growth effects and is packed with antioxidant
factors which can stimulate stem cells RF is a perfect serums and thermo-masks for the
and fibroblasts which in turn produces best results.
new collagen, elastin and regulates the
blend of painless
cell turn over. She further elaborates, technology and Thread-lift: Thread-lifts help lift up
“PRP is prepared from the patients’ own pampering from the sagging areas of the face, especially
blood and either injected intradermally jawline and heavy cheeks. Dr Dixit
anti-ageing procedure
with an insulin syringe or with a gun. It shares, “Treatments are not painful,
can also be infused after derma roller bucket. take less than an hour. The results are
either by electroporation or ultrasound immediate, and last up to eight months.”
infusion technology.” She adds that usually
the PRP therapy is administered every month DEVICES IN VOGUE
for four sessions. It improves the skin hydration, tex ture, Many devices are used for anti-ageing such as
elasticity, and you can see reduction of fine lines and a radiofrequency (RF), HIFU, Ulthera, and fractional
glowy skin. Maintenance sessions are advised twice or resurfacing lasers, to name a few. All devices, with evolved
thrice yearly. It takes a couple of days for the roller of technology, work around similar principles.
injection marks to settle down. Antibiotic cream is advised Speaking of her all-time personal favourite,
for two days. Daily routine of moisturiser and sunscreen Dr Tekchandani mentions, “RF”. She adds, “It is a perfect
should be recommended. blend of painless technology and pampering from the anti-
ageing procedure bucket. It is also pocket-friendly with
Fillers: Fillers are recommended by doctors for skin amazing results.”
rejuvenation. As Dr Nerurkar says, “These treatments can On his part, Dr Parashar mentions HIFU, PRP centrifuge
lift the skin, make the face look less tired, less saggy and and test tubes, hydrafacial machine, and microneedling
less angry. It helps reduce the hollowing below the eyes, RF, as among the trending devices; and Dr Nerurkar lists
in the cheeks, near the nose and rejuvenate the skin.” She monopolar radiofrequency (Thermage), HIFU, multipolar
adds that it can be a substitute for face lift surgeries in radiofrequency, and carbon dioxide laser.
some cases. “When the skin is minimally drooping, these
treatments play an important role, to make it look more
youthful and attractive.” These treatments should be done
by experienced injectors. The side-effects can be bruise,
lumps, nodules, infections to intravascular complications.
One good treatment done requires a follow up after one to
one and a half years.
Speaking of dermal fillers, Dr Tekchandani shares,
“Liquid facelifts as we call it at Tender Skin are minimally
invasive procedure with good and long-lasting results.
It is recommended in patients where there is a loss of
volume or even for lifting purposes. Hydrating fillers are
my personal favourite as they work like magic in overall
hydration and gives the skin the natural supple texture.”
She adds that the result of fillers lasts from six months
Aesthetic Medicine • September-October 2020 17COV E R F E AT U R E
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ANTI-AGEING
Devices used by Dr Chhabra for anti-ageing treatment dermatologist, you are not just a doctor but a counselor,
include Ultherapy, Thermage, Scarlet, Exilis, Q-switched a surgeon, a friend, an all in one package for your client.”
Nd:YAG Laser, Erbium YAG Laser, and microdermabrasion. She recommends a detailed history along with drawing the
And, in Dr Surapaneni’s clinic, she shares, “We use golden ratio for the client’s face to be able understand the
Ultraformer III a HIFU device; Accent radiofrequency, areas that need work and how we can have a multiphase 3D
which is a unipolar and bipolar device; and EndyMed 3Deep approach to fulfilling the client’s requirement.
radiofrequency device.” This is used for skin tightening, body Each person ages a different way, some with volume
contouring, fractional resurfacing with RF, microneedle RF loss needing filler, some with sagging, needing threads
for textural improvement. “We also use Spectra Q-Switched and devices, says Dr Dixit. She points out to habits such as
Nd:YAG laser to treat pigment abnormalities. Luminis M22 diet, exercise and smoking that also affect the skin. Plus,
IPL platform for wide indications such as pigment lightening she says that the budget needs to be kept in mind while
and vascular telangiectasia. Lutronic eCO2 is a robust designing a treatment plan.
machine for resurfacing and removal of solar keratoses and Dr Nerurkar shares her perspective: “Every patient
skin tags. We use the Cooltech machine for body contouring is different and so is their requirements. All anti-ageing
to reduce pockets of fat.” procedures are based on the signs of ageing seen on their
face. It also depends on the patient preference, as not all
A PERSONALISED APPROACH of them agree for an injectable treatment.”
Building personal relationships with your clients is key to Listing key factors that dermatologists need to
understanding their expectations right to be able to deliver focus on while they approach a patient, Dr Parashar
the best results. Also, a personalised approach becomes lists: “Assessment of face; expectations of the
important here as every patient has different skin types patient; explanation of the procedure and what can be
and may react differently to molecules. achieved; realistically, what can be done is conveyed in a
“I always say this,” says Dr Tekchandani, “…as a simple language.”
18 Aesthetic Medicine • September-October 2020COV E R F E AT U R E
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ANTI-AGEING
#STAYSAFE
Considering the pandemic times, safety precautions at temperature and oximeter checks at entry with
clinics become even more paramount. Patient safety complete patient sanitization should be mandatory
comes first, and medical practitioners must follow The patient should not have any symptoms such as
several safety measures to contain the spread of the fever and sore throat.
virus. Aesthetic Medicine lists key recommendations If they have travelled, ensure the quarantine period is
shared by dermatologists featured in this story: done.
Make your patient feel safe and comfortable.
Start your day at the clinic(s) with a safety pledge Use safety gears such as masks, gloves, and head
as a reminder to the team to do everything it takes shield.
to maintain your own safety and the safety of your PPE kits should be used while doing procedures.
clients for your families and theirs. Opt for best practices such as clinic sanitisation, shoe
Patient history should be taken on call before they covers, disposable gloves, and sheets.
visit clinic (inform them to not bring companions to Use double glove technique and ensure use of glass
avoid crowding and respect their time slot to avoid shield.
delays and waiting time for other patients). Avoid lengthy procedures that last more than 20-30
COVID consent is important before doing any minutes.
procedures or consultations. Ask the patient to wear masks while doing body and
Staggered appointments are imperative. Ensure hair treatments.
limited appointments in 1 slot. Appointment When they come to the clinic, check their vitals such
management is key to maintain social distancing and as temperature and oxygen saturation with pulse
sanitization protocols between two clients. oximeter.
Before calling the patient for the procedure, ensure Ensure to use disposables and sanitize before and
there is no case of COVID in their homes or buildings after each procedure to avoid cross contamination.
Ask your clients to download the Aarogya Setu app,
Do not let your guard down just because things are opening up!
AM
Aesthetic Medicine • September-October 2020 19OPINION
SKIN / DERMATOLOGY www.aestheticmed.in
The anti-ageing
approach
Skin appearance and characteristics change with ageing of body. Dr Sudhavani
Damarla, elaborates on ageing, people’s perspective around it and treatment options.
T
he desire for skin with homogenous colour and
texture, no wrinkles or sagginess, and lustrous
hair has motivated people to look for antiaging
treatments. People who appear younger are rated
as more attractive in comparison to those who
look older. According to studies, youthful skin that appears
attractive as well as healthier is preferred among humans.
Skin texture distribution studies demonstrate that the
effect of distribution of skin tone can account for up to 20
years of perceived age.
COMMON SIGNS OF INTRINSIC AGEING ARE:
Fine lines and wrinkles.
Thin and somewhat transparent skin.
Loss of underlying fat resulting into hollowed cheeks
and eye sockets with lost firmness on hands and neck.
Bone loss resulting into bones shrinking away from
skin. This results into sagging.
Dry itchy skin.
Insufficient sweating to cool the skin.
Hair turn grey and eventually white.
Hair loss.
Unwanted hair.
Nail plate thins, development of ridges.
A significant loss of fibrillin-positive structure and
decreased collagen type-7 may play a role in wrinkling as it
weakens the bond between epidermis and dermis of skin
that undergoes extrinsic ageing. The sparse distribution
and reduced content of collagen in photoaged skin may dermatosis. Advances in medical field and overall improved
be due to enhanced collagen degradation by matrix socio-economic status have increased the life expectancy,
metalloproteinases (MMPs), serine, and other proteases. which has resulted into exposure to environmental factors,
Collagen is irregular and poorly organised in older skin, the irritants, and toxic agents for a longer time.
ration of collagen-3 to collagen-1 increases mainly due to
loss of collagen-1. Glycosaminoglycans (GAGs) are among Anti-ageing treatments
the primary dermal skin matrix constituents, which help in Various in-office procedures and topical treatments,
binding water. In photoaged skin, they may be associated most intended to ‘resurface’ the epidermis, are available for
with abnormal elastotic material, thus not able to function treatment of ageing skin. This essentially means removal of
optimally. Collagen, elastin, and GAGs are primary damaged epidermis (and sometimes dermis) and replacing it
components that are targets of anti-ageing research. with remodelled tissue. Different individuals have different
Ageing skin is markedly susceptible to dermatological perceptions about how their anti-ageing product works,
disorders due to changes induced by intrinsic and extrinsic based on what is bothering them most about their ageing
ageing. The changes may occur naturally, or due to any skin. A study that gauged the perception about
20 Aesthetic Medicine • September-October 2020OPINION
www.aestheticmed.in SKIN / DERMATOLOGY
anti-ageing products in women aged 25-60 years showed use. When topically applied, retinoids inhibit AP-1 and thus
that majority of women understood that their anti-ageing inhibit the expression of MMPs and preventing the collagen
product reduced wrinkles (55 per cent of women) and made degeneration. Epidermal thickness and anchoring fibrils are
their skin whiter (30 per cent). Thus, it seems that wrinkles increased, and skin undergoing intrinsic ageing may also
and skin tone are the most noticed signs of ageing skin, benefit from topical retinoids.
and satisfaction with treatment is gauged on the extent of
effect of anti-ageing products on these two parameters. Telomere modification: Although telomere modification
appears ideal for reversal of skin ageing and high-
The treatment options are: level of expression of telomere reverse transcriptase
Antioxidants: Antioxidants treat the ageing skin by (TERT) in skin fibroblasts and keratinocytes results into
scavenging the reactive oxygen species (ROS) that increased proliferative capacity, risk of epidermal
are already formed. ROS activate the AMPK carcinogenesis meanwhile increase. Thus,
pathway, thus increasing the production of this approach needs further investigation
matrix metalloproteinase, which degrades for safety of enhanced proliferation.
the collagen. Antioxidants such as
vitamin C and vitamin E, antioxidant Anti-inflammaging: ‘Inflammaging’
enzymes like superoxide dismutase,
Wrinkles and skin tone refers to chronic low-grade
catalase, glutathione peroxadise, are the most noticed signs inflammation that occurs with
coenzyme Q10 can prevent this by of ageing skin. advanced age. However, as the
scavenging ROS. Plants like green tea mechanism of skin inflammaging is
and aloe vera are useful natural sources little understood, the progress made
of antioxidants. For example, it was found in developing the treatments for skin
that Epigallocatechin galllate (EGCG), which inflammaging is also little. Treatment of
is found in green tea, can prevent skin ageing human fibroblast cells using UV-absorbing
with the help of epidermal growth factor compound mycosporine-like amino acids (MAAs)
receptor (EGFR) pathway, providing better skin structure result into suppression of cyclo-oxygenase-2 (COX-2) gene
as compared to control. N-acetyl cysteine, precursor of expression, which is typically increased in response to skin
glutathione, appears effective in treatment of age-related inflammation. Also, the expressions of skin ageing-related
decline in tissue regeneration, indicating its potential proteins elastin and procollagen C-proteinase enhancer are
against skin ageing. strongly suppressed after UV irradiation but restored after
However, some researchers suggest that antioxidant MAAs treatment to normal levels as in control. There are
supplements do not possess preventive effects against also other anti-inflammaging additives like vitamins A, C, D,
chronic diseases. Excessive supplementations of E and K, and green tea.
β-carotene and vitamins A & E, for example, is potentially
harmful, especially in well-nourished populations. It is
stated that the optimal source of antioxidants comes
from diet and not supplements and pills. As ROS have their
physiological functions, it is inadvisable to eliminate all
ROS. Antioxidants appear to offer benefits in skin ageing
only if ROS level is reduced to those of healthy cells.
Stem cell therapy: Stem cell therapy is a promising option for
the treatment of skin ageing. Adipose tissue transplantation
could provide better skin quality at the recipient site, as well
as increased skin volume. Further experiments showed
that adipose-derived stem cells (ADSCs) contribute to skin
regeneration during ageing. In clinical tests, autologous fat
grafting was found to rejuvenate the skin undergoing ageing
and increase the volume of periocular and perioral skin in
participants aged 50 years on average. ADSCs have been
demonstrated to produce a series of growth factors, and
thus may influence the surrounding cutaneous cells through
the secretions. They also seem to trans-differentiate into
epithelial stem cells after fat grafting. This work gives some
information on the way fat grafts may rejuvenate the skin.
Retinoids: Retinoids are chemically similar to vitamin A
(retinol), tretinoin being the first to gain approval for clinical
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