A Study on Identifying the Causes of Hypoglycemia and to Implement a Process to Prevent Hypoglycemia Events in Diabetic Patients in a Tertiary ...
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International Journal of Science and Healthcare Research Vol.7; Issue: 2; April-June 2022 Website: ijshr.com Original Research Article ISSN: 2455-7587 A Study on Identifying the Causes of Hypoglycemia and to Implement a Process to Prevent Hypoglycemia Events in Diabetic Patients in a Tertiary Care Hospital, Hyderabad Bhagya Lakshmi1, Usha Prabhakar2, Naga Sireesha3, Maryline Flinsi4, Dr. N. Balakrishna5 1 Nursing Quality Coordinator-Apollo Health City, Hyderabad 2 Regional Chief Nursing Officer-Apollo Telangana Region 3 Nursing Superintendent -Apollo Health City, Hyderabad, 4Principal Apollo School of Nursing-Delhi 5 HOD- Department of Statistics, AHERF- Apollo Health City, Hyderabad Corresponding Author: Bhagya Lakshmi DOI: https://doi.org/10.52403/ijshr.20220412 ABSTRACT details and implemented a process to identify and treat hypoglycemia in time. Background: Low blood glucose is common Result: Mean Hypoglycemia was similar across among people with type 1 diabetes and among age, gender, based on diet intake and also based people with type 2 diabetes who take insulin or on insulin duration of action. Mean oral Hyperglycemic agents. In a large global Hypoglycemia was significantly (P
Bhagya Lakshmi et.al. A study on identifying the causes of hypoglycemia and to implement a process to prevent hypoglycemia events in diabetic patients in a tertiary care hospital, Hyderabad Both the American Diabetes MATERIAL & METHODS Association (ADA) and the European This was a prospective and Medicines Agency have defined observational study. hypoglycemia as “any abnormally low The data for this study was obtained plasma glucose concentration that exposes from tertiary care hospitals between August the subject to potential harm” with a 2021 to March 2022. proposed threshold plasma glucose value A total of 34 Hypoglycemia events
Bhagya Lakshmi et.al. A study on identifying the causes of hypoglycemia and to implement a process to prevent hypoglycemia events in diabetic patients in a tertiary care hospital, Hyderabad Figure 2: Process flow to treat Hypoglycemia promptly Statistical Methods occurrence, its association with symptoms Mean and SD values were calculated as given in Table 1, by ’t’ test. Multiple for Quantitative variables. Proportions (%) linear regression mode; was performed to were calculated for Qualitative variables study the relationship of hypoglycemia with like age, gender, time of occurrence, symptoms, time of occurrence and action hypoglycemia events association with taken. Level of significance was considered symptoms, what was the action taken. Mean as 0.05. SPSS version 24 was used for all values of hypoglycemia events were statistical methods. compared by age, gender, time of RESULTS Table 1 Baseline Characteristics Categories N Mean In Relation To SD P-Value Hypoglycemia Event Age >=66 21 55.2 10.28 0.786
Bhagya Lakshmi et.al. A study on identifying the causes of hypoglycemia and to implement a process to prevent hypoglycemia events in diabetic patients in a tertiary care hospital, Hyderabad sugar (61.8) water and intravenous fluids progressively reduced from (20 episodes in (56.3). 2 Months period to34 episodes in 7 months duration). Table 2: Multiple Linear regression model of Hypoglycemic events with Symptoms, Time of occurrence and Action taken Multiple Linear regression model of Hypoglycemic events CONCLUSION with Symptoms, Time of occurrence and Action taken Implementation of structured S no Model P2 (%) P value 1 46.9-4.441 Sympotoms+4.51 training program about the most common Time of occerence+8.977 38.6 0.002 causes leading to hypoglycemia and the Action taken 2 49.2+11.353*Action taken 29.7 0.001 process of correcting event on time reduce Note: * Indicates Significant morbidity related to hypoglycemia. Counselling programme to the patients Table 2 shows the relationship of regarding hypoglycemia, its causes and hypoglycemia with symptoms, time of symptoms, adverse effects as well as occurrence and action taken. Level of appropriate management should be significance was considered as 0.05. encouraged. The knowledge about The most common causes were symptoms of hypoglycemia is an important insufficient diet intake, and inadequate step to self-care practice, because informed insulin doses management as per diet intake. people are more likely to have better Consequently, we implemented protocols to practice.9 Having good knowledge about guarantee a minimal intake of CHO hypoglycemia is positively associated with (intravenous and/or oral), and discussions good hypoglycemia prevention practice.10 with dietician team for same. In addition, we developed process to identify the Acknowledgement: None hypoglycemia events and defined a process for prompt treatment of event to reduce Conflict of Interest: None severity. By these actions, the rate of Source of Funding: None hypoglycemia progressively reduced from (20 episodes in 2 Months period to34 Ethical Approval: Approved episodes in 7 months duration). REFERENCES DISCUSSION 1. Muche EA, Mekonen BT. Hypoglycemia This study provided baseline data prevention practice and its associated regarding the common causes of factors among diabetes patients at university hypoglycemia and process of correcting teaching hospital in Ethiopia: Cross- event on time which was included in sectional study. PLoS One. 2020; 15(8):e0238094. Published 2020 Aug 21. structured training programme to all health doi:10.1371/journal.pone.0238094 care workers in order to identify, treat and 2. American Diabetes Association Workgroup prevent hypoglycemia. Mean Hypoglycemia on Hypoglycemia. Defining and reporting was similar across age, gender, based on hypoglycemia in diabetes. Diabetes Care. diet intake and also based on insulin 2005;28:1245-9. [PubMed] [Google duration of action. Scholar] Mean Hypoglycemia was 3. Guideline on clinical investigation of significantly (P
Bhagya Lakshmi et.al. A study on identifying the causes of hypoglycemia and to implement a process to prevent hypoglycemia events in diabetic patients in a tertiary care hospital, Hyderabad Rev Endocrinol. 2016; 12(4):222–32. doi: 10.2337/dc12-2480. Epub 2013 Apr 15. https://doi.org/10.1038/nrendo.2016.15. PMID: 23589542; PMCID: PMC3631867. 5. Jabbour, Serge et al. “Dapagliflozin in 9. Peyrot M, Rubin RR (1994) Modelling the patients with type 2 diabetes mellitus: A effect of diabetes education on glycaemic pooled analysis of safety data from phase control. Diabetes Educ 20: 143-148. IIb/III clinical trials.” Diabetes, obesity & 10.1177/014572179402000210 metabolism vol. 20, 3 (2018): 620-628. 10. Gebremichael GB, MariyeZemicheal T. doi:10.1111/dom.13124 Hypoglycemia Prevention Practice and 6. Mathew P, Thoppil D. Hypoglycemia. 2022 Associated Factors among Diabetic Patients Jan 4. In: StatPearls [Internet]. Treasure on Follow-Up at Public Hospitals of Central Island (FL): StatPearls Publishing; 2022 Zone, Tigray, Ethiopia, 2018. International Jan-. PMID: 30521262. Journal of Endocrinology.2020. March 13; 7. Shriraam V, Mahadevan S, Anitharani M, et 2020. al. Reported hypoglycemia in Type 2 diabetes mellitus patients: Prevalence and practices-a hospital-based study. Indian J How to cite this article: Lakshmi B, Prabhakar Endocrinol Metab. 2017; 21(1):148-153. U, Sireesha N et.al. A study on identifying the doi:10.4103/2230-8210.196002. causes of hypoglycemia and to implement a 8. Seaquist ER, Anderson J, Childs B, Cryer P, process to prevent hypoglycemia events in Dagogo-Jack S, Fish L, Heller SR, diabetic patients in a tertiary care hospital, Rodriguez H, Rosenzweig J, Vigersky R. Hyderabad. International Journal of Science & Hypoglycemia and diabetes: a report of a Healthcare Research. 2022; 7(2): 79-83. DOI: workgroup of the American Diabetes https://doi.org/10.52403/ijshr.20220412 Association and the Endocrine Society. Diabetes Care. 2013 May; 36(5):1384-95. ****** International Journal of Science and Healthcare Research (www.ijshr.com) 83 Vol.7; Issue: 2; April-June 2022
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