2020 JAMES D. EASON TRANSPLANT INSTITUTE AT METHODIST UNIVERSITY HOSPITAL

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2020 JAMES D. EASON TRANSPLANT INSTITUTE AT METHODIST UNIVERSITY HOSPITAL
JAMES D. EASON
TRANSPLANT
INSTITUTE
AT METHODIST
UNIVERSITY
HOSPITAL

2020
2020 JAMES D. EASON TRANSPLANT INSTITUTE AT METHODIST UNIVERSITY HOSPITAL
LETTER ROM        Dear Friends,

    DR. JAMES EASON   Despite the challenges presented over the past year due to the COVID-19 public health crisis, the James D. Eason
                      Transplant Institute remained focused on providing comprehensive organ transplantation care to over 270 patients and
                      their families.

                      Beyond expert clinical care, our team continued to focus on providing holistic care to patients throughout their
                      transplant journey and also expanding access to serve all patients in need, regardless of their circumstances.

                      The expert physicians on our team have performed more than 5,400 organ transplants since our first kidney transplant
                      in 1970, and we continue to save more lives through liver, kidney, and pancreas transplantation.

                      We are also proud to continue to be a national-leader and expert in live-donor liver and kidney transplantation.

                      The beautiful, state-of-the-art transplant facilities within Shorb Tower at Methodist University Hospital afford our staff
                      and patients with a healing, peaceful, and highly functional space that promotes both patient experience and transplant
                      outcomes and serves as a catalyst for innovation in the care we provide.

                      In collaboration with our academic partner, the University of Tennessee Health Science Center, our Physicians and
                      Clinical Research Faculty at the Transplant Research Institute continue to implement research studies using the latest
                      technology and knowledge to both advance organ transplant outcomes and increase the number of available organs for
                      transplantation.

                      Serving as a testament to our commitment to this work, our program remained on track in our pursuit of becoming a
                      best-in-class, program of choice for patients in need of organ transplantation. We exceeded the total number of
                      surgeries provided in 2019, providing over 270 transplants in 2020.

                      We couldn t have gotten to where we are today in the most advanced and state-of-the-art facility, providing
                      comprehensive organ transplant care to hundreds of patients annually, operating a robust research program, with an
                      expert research and clinical team without the philanthropy and support of our community, friends, and advocates.

                       iving, both in terms of philanthropy and the gift of life and organ donation, continues to transform our Institute into a
                      beacon of hope for those in our community and beyond who need life-saving organ transplantation.

                      As we look ahead to 2021, we will continue to pursue excellence in the care we provide to our patients and will
                      aggressively push the boundaries of organ transplantation science. our support makes everything we do possible, and
                      we are most grateful.

                      Sincerely,

                      Dr. James D. Eason
                      Program Director
                      James D. Eason Transplant Institute at
                      Methodist University Hospital

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2020 JAMES D. EASON TRANSPLANT INSTITUTE AT METHODIST UNIVERSITY HOSPITAL
2020                                                                                                                                '
IMPACT                                                                             A ATHER            SON S TRANSPLANT STORY
NUM ERS
                                                                                   When Patrick Manning found out his Dad, Mark Manning, needed a liver transplant, he
                                                                                   didn’t hesitate, “I asked every day, ‘When can I call? Who do I need to call? ”
                                                                                   Just months later, Patrick received the call from the team at the James D. Eason
                                                                                   Transplant Institute at Methodist University Hospital informing him that he was approved
                                                                                   to be his Dad’s live liver donor.
                                                                                   He shared, “I felt elated because I could see my Dad walk my sister down the aisle. I would
                                                                                   have him in my life. He could enjoy retirement. ”
                                                                                   In April of 2020, despite the worldwide COVID-19 public health crisis, the Mannings
                                                                                   successfully underwent liver transplantation surgery at Methodist University Hospital.
                                                                                   Patrick donated 65% of his healthy liver to Mark, and, within weeks, they both had
                                                                                   healthy, regenerated, full-size livers.
                                                                                   Even though they were unable to have their loved ones visit them in the hospital, the two
                                                                                   shared that they received immense support from their caregivers and from one another.
                                                                                   The James D. Eason Transplant Institute is among an elite few programs in the United
                                                                                   States offering the option of live liver donor transplant surgery.
                                                                                   For patients like Mark who may be on an organ waiting list for years or even pass away
                                                                                   before they receive an organ donation, this innovative option is truly life-saving.
                                                                                   Today, Patrick and Mark are both feeling well.
                                                                                   Mark shared, “My recovery was remarkably fast. I feel better now than I did before.”

                                                                                                                                                     “   I felt elated
                                                                                                                                                     because I could
                                                                                                                                                     see my Dad walk
   119            131                15                2                                                                                             my sister down
   Adult Liver    Adult Kidney       Kidney/Pancreas   Pediatric Liver
   Transplants                       Transplants       Transplants
                                                                                                                                                     the aisle. I would
                  Transplants
                                                                                                                                                     have him in my life.
                                                                                                                                                     He could enjoy
    5             214                50+               200+                                                                                          retirement.          ”
    Pediatric     Pediatric Kidney   Years of          Dedicated Organ
     idney        Transplants        Transplantation   Transplantation                                                                                   -
    Transplants
                                     Experience        Professionals

                                                           * 1/1/2   to 12/ 1 /2
2020 JAMES D. EASON TRANSPLANT INSTITUTE AT METHODIST UNIVERSITY HOSPITAL
TRANSPLANT
 RESEARCH
 INSTITUTE                                                                                                                                  :
                                                                      sin         se uencin to identify ene e ression and mi     chan es this study
                                                                    seeks to better understand how to address the occurrence of Ischemia e erfusion
                                                                    Injury in liver donation stora e and trans lantation.
                                                                           :
                                                                     his IH funded study established a network of researchers to e       lore the lon
                                                                    term outcomes of kidney trans lantation.

                                                                      eekin to better identify uality or ans for trans lantation this study is workin to
                                                                    identify biomarkers that can classify or an uality usin   ersufate sam les from
                                                                      atients with different outcomes and ne t eneration se uencin .
                                                                                                                     K                          :
                                                                    In collaboration with orthwestern niversitity and niversity of aryland this
                                                                    study aims to define reasons for recurrent ocal e mental lomerulo clerosis
                                                                             in kidney trans lant atients usin enomics includin sin le cell and
                                                                           se uencin .

                                                                      he ur ose of this study is to evaluate the       s ecific  ell immune res onse
                                                                    in H    uninfected renal trans lant reci ients by com arin trans lants from HCV
                                                                    infected and uninfected donors.
                                                                                                                 K
                                                                      his collaborative study across research institutions seeks to ain a better
                                                                    understandin of the outcomes of trans lantin kidneys from H                  ositive
                                                                    kidney donors to H      ne ative reci ients.
                                                                                                                               K
                                                                     he ur ose of this study is to evaluate the im act of De    ovo He atitis     infection
                                                                    on dd cf D     llo ure in kidney trans lant reci ients.
                                                                                                  :
                                                                     his study is e lorin the outcomes of usin       ormothermic e vivo liver erfusion
                                                                             for the assessment of allo raft function and restoration of intracellular
                                                                    ener y stores of livers rior to trans lantation.
 he ames D. ason rans lant Institute at ethodist niversity
Hos ital in artnershi with the niversity of ennessee Health
                                                                      everal studies are underway usin rodent trials to investi ate the thera eutic use
 cience enter      H    is dedicated to research in the field of
                                                                    of itochondria hera y for im rovin healthy liver function in non alcoholic fatty
or an trans lantation.
                                                                    liver disease        D ; Ischemia e erfusion Injury I I ; and in normothermic e
  ith   H      he ames D. ason rans lant Institute o erates         vivo erfusion um to rolon the cold ischemia times.
a ranslational esearch lab where skilled researchers and
 hysicians are ursuin e cellence in atient e erience clinical         his collaborative study with Harvard edical chool and assachusetts eneral
 uality and safety and ushin the boundaries of trans lant           Hos ital is e aminin the effectiveness of mitochondria thera y in decreasin
science throu h research.                                           ischemia re erfusion injury to livers durin the trans lantation rocess.
  sin both basic and clinical research our research team              K
  hysicians and faculty are focused on rovidin cuttin ed e           his IH funded study is evaluatin      atient outcomes from kidney care on the renal
trans lant thera ies and increasin the availability of or ans for   allo rafts re istry.
trans lantation as well as lon term or an trans lantation
  atient outcomes.
2020 JAMES D. EASON TRANSPLANT INSTITUTE AT METHODIST UNIVERSITY HOSPITAL
INSTITUTE                                                                                                                                          The Transplant
TEAM                                                                                                                                               Institute team
                                                                                                                                                   is comprised of
                                                                                                                                                   200 Methodist
                                                                                                                                                   Associates who
                                                                                                                                                   represent every
                                                                                                                                                   element of the care
                                                                                                                                                   provided.

                                                                             TRANSPLANT SURGEONS

                                                                             Dr. James Eason          Dr.                     Dr. Nosratollah
                                                                             Program Director         Surgical Director of    Nezakatgoo
                                                                                                      Liver Transplantation   Surgical Director
                                                                                                                              of Pancreas
                                                                                                                              Transplantation

                                                                             Dr. Ryan Helmick         Dr. Peter Horton        Dr. Corey Eymard
                                                                             Surgical Director of     Transplant Surgeon      Transplant Surgeon
                                                                             Kidney Transplantation

                                                                             TRANSPLANT HEPATOLOGISTS
  s a result of the com ellin work takin   lace throu h the ames D. ason
  rans lant Institute and the com le needs of the Memphis and Mid-South
community the ro ram has recruited a stellar team of hysicians care ivers
and research scientists. he Institute em loys over        ssociates who
re resent the entire s ectrum of care. e are roud of our current team that
includes the followin skilled and dedicated rofessionals                     Dr. Satheesh Nair        Dr.                     Dr. Jiten Kothadia
                                                                             Medical Director of      Transplant              Transplant
                                                                             Liver Transplantation    Hepatologist            Hepatologist

                                                                             TRANSPLANT NEPHROLOGISTS

                                                                             Dr. Manish Talwar        Dr. Vasanthi            Dr. Anshul Bhalla
                                                                             Medical Director         Balaraman               Transplant
                                                                             of Kidney                Medical Director of     Nephrologist
                                                                             Transplantation          Live Donor Kidney
                                                                                                      Transplantation
2020 JAMES D. EASON TRANSPLANT INSTITUTE AT METHODIST UNIVERSITY HOSPITAL
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2020 JAMES D. EASON TRANSPLANT INSTITUTE AT METHODIST UNIVERSITY HOSPITAL 2020 JAMES D. EASON TRANSPLANT INSTITUTE AT METHODIST UNIVERSITY HOSPITAL 2020 JAMES D. EASON TRANSPLANT INSTITUTE AT METHODIST UNIVERSITY HOSPITAL 2020 JAMES D. EASON TRANSPLANT INSTITUTE AT METHODIST UNIVERSITY HOSPITAL
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