2019-2020 Treatment Results - FOR PATIENTS AND CAREGIVERS - Cancer Treatment Centers
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Cancer Treatment Centers of America Global, Inc. 2019-2020 Treatment Results FOR PATIENTS AND CAREGIVERS Elaine B., Breast Cancer CTCA Tulsa LENGTH OF LIFE | QUALIT Y OF LIFE | PATIENT EXPERIENCE | PATIENT SAFE T Y | QUALIT Y OF CARE
Table of Contents PATIENT TREATMENT RESULTS 2019 | 2020 SECTION 1 SECTION 4 Dear Patients and Caregivers, About this Report Our Patient Experience Results 3 Why We Publish Our Treatment Results 35 HCAHPS Inpatient Survey We believe all patients should have access to as much information as possible in order to make Background and Methodology the most informed decisions about their care. As part of that commitment, we are pleased to share 3 Our Commitment to Transparency with you this seventh annual edition of our Patient Treatment Results. Cancer Treatment Centers 3 Our Beginnings 36 Inpatient Satisfaction Results of America® (CTCA) was among the first cancer care providers in the nation to make treatment 42 OAS CAHPS Survey Background 4 Our Beliefs results available to the general public, and, to our knowledge, this is the most comprehensive and Methodology presentation of treatment results now published by any cancer care provider. It reflects the quality 4 Accessibility 42 Outpatient and Ambulatory Surgery of clinical care we have provided to patients from around the world at our comprehensive care and 4 Health Insurance and Verification Patient Satisfaction Results research centers and outpatient care centers in Atlanta, Chicago, Philadelphia, Phoenix and Tulsa. 5 Sponsors of this Report 46 Outpatient Survey Background Five-year survival rates for CTCA® patients treated between 2000 and 2015 are provided for 11 6 CTCA Patient Demographics and Methodology cancer types. For reference, we have also provided companion data for the same cancer types 46 Outpatient Satisfaction Results and timeframe as reported by the National Cancer Institute in its Surveillance, Epidemiology and SECTION 2 End Results (SEER) Program, which is undertaken in collaboration with the American College of 52 Physician Transparency Star Rating Surgeons and American Cancer Society. Our Length of Life Results Background, Methodology and Results 9 Independent Researchers’ Letter The CTCA patient survival data appearing in this publication were independently analyzed and SECTION 5 interpreted by Bert Spilker, MD, PhD, and Chengjie Xiong, PhD. Their biographical sketches are 10 Statistical Methodology included in this publication. Neither is affiliated with, or employed by, CTCA. 13 Breast Cancer Safe Care, Quality Care 53 Our Philosophy and Methodology Additionally, we have included data on various safety and quality of care measurements during 14 Colon Cancer treatment, critically important results not commonly reported by most cancer providers, as well 54 AHRQ Survey: Patient Safety Culture 15 Esophageal Cancer as patient self-reports of quality of life and the overall patient experience. 58 Quality Metrics 16 Kidney Cancer All data sources and survey methodologies are provided in their respective sections throughout 63 Overall QOPI Quality Score and QOPI Metrics 17 Non-Small Cell Lung Cancer the publication. 66 Project-Specific Areas of Focus 18 Small Cell Lung Cancer We hope you find this important information valuable, and we would be pleased to respond to 19 Ovarian Cancer SECTION 6 any feedback or questions you may have about the results. 20 Pancreatic Cancer Our Clinical Leadership Thank you for your interest in Cancer Treatment Centers of America. 21 Prostate Cancer 69 Medicine & Science Sincerely, 22 Rectal Cancer 69 Department Chairs and Vice Chairs 23 Stomach Cancer 71 Chiefs of Staff SECTION 3 SECTION 7 Our Quality of Life Results Our Research Maurie Markman, MD 25 Assessment Background 73 Publications and Presentations President, Medicine & Science and Methodology Cancer Treatment Centers of America 79 Accreditations and Certifications 27 Quality of Life Results by Cancer Type 32 Quality of Life Results in Aggregate and by Facility © 2019 IPB
About this Report 1 Our Length of Life Results Our Vision To be recognized and trusted by people Our Quality of Life Results living with cancer as the premier center for healing and hope. Our Mission Our Patient Experience Results CTCA® is the home of integrative and compassionate cancer care. We never stop searching for and providing powerful and innovative therapies to heal the whole person, Our Patient Safety and Quality Results improve quality of life and restore hope. Our Values Hopeful Our Clinical Leadership Compassionate Empowering Ethical Responsive Innovative Our Research Publications Team Spirited
About This Report Why We Publish our Treatment Results At Cancer Treatment Centers of America® (CTCA), we became one of the first in the country to offer a full believe in empowering patients. We believe patients range of integrative treatment services, including deserve access to information—especially health surgery, chemotherapy and radiation therapy as outcomes, including survival, patient safety and well as nutrition, mind-body and spiritual support. quality care data as well as patient self-reported data In 1990, CTCA opened a second hospital, located on care experience and symptom management. in Tulsa, Oklahoma, establishing itself as a premier When patients have access to information about center of hope and healing for cancer patients. the centers and professionals to whom they entrust their lives, they are able to make more As demand grew, the CTCA hospital in Zion was informed decisions about their care. expanded twice. In 1991, CTCA broke ground on a five-story, 78,886-square-foot facility. Then in OUR COMMITMENT TO TRANSPARENCY 2015, a six-story 168,078-square-foot inpatient tower became the centerpiece of a campus-wide At CTCA®, we believe that transparency in the modernization. publication of our treatment results is vital to upholding our promise to patients and their CTCA also expanded its presence in Tulsa by families. Regardless of the outcome, it holds us opening a state-of-the-art hospital in 2005. The accountable to continually improve the care we stunning 195,845-square-foot center became deliver. We engage leading independent research Oklahoma’s only major hospital completely organizations, such as Bert Spilker & Associates, LLC, focused on treating cancer. Also in 2005, CTCA Press Ganey® and Healthcare Performance Philadelphia opened its doors, becoming the first Improvement (HPI®) to conduct various analyses CTCA hospital on the East Coast. of our treatment results. We utilize valid and tested CTCA Phoenix, a modern 210,000-square-foot tools and participate in nationally recognized hospital located in Goodyear, Arizona (suburban activities to further our commitment to safe, high- Phoenix) joined the CTCA family in 2008. In 2012, quality care for the patients we serve. CTCA Atlanta began welcoming patients to its location in suburban Newnan. OUR BEGINNINGS Job L. | E S O P H AG E A L C A N C E R | CTCA Tulsa Building on the goal of offering patients increased In the early 1980s, Richard J Stephenson and his access to advanced cancer therapies and family suffered the loss of their mother, Mary personalized care in convenient, cost-effective “Throughout my treatment, I was impressed with the commitment to the Mother Brown Stephenson, to cancer. When she died, her outpatient settings, in 2018 and 2019 CTCA grieving son and his family asked, “What would it opened five outpatient care centers in Chicago, Standard® of care, the belief that patients are taken care of the way you would want take to actually change the face of cancer care?” Phoenix and their surrounding communities. any member of your family treated. CTCA truly cared about my patient experience, In 1988, CTCA was born, founded on what is now known as the Mother Standard® of care—a patient- treating my whole person and actively monitoring my quality of life. Any issues were centered approach that combines compassion quickly addressed, and I had access to a variety of supportive care therapies that I with advanced technology and treatment options. took advantage of.” The American International Hospital in Zion, Illinois, located between Chicago and Milwaukee, served as the first CTCA location. With Mr. Stephenson as chairman of the board, the cancer program ABOUT THIS REPOR T 3
Sponsors of this Report OUR BELIEFS Accessibility, Services and Insurance: The CTCA Comprehensive Cancer Care Network Reducing the Stress of Cancer Care of hospitals and outpatient care centers offers an integrative approach to care that combines surgery, radiation, chemotherapy and ACCESSIBILITY immunotherapy with advancements in precision CTCA understands that speed and accessibility of cancer treatment and supportive therapies care are important to patients and their caregivers, SPONSORS OF THIS REPORT designed to manage side effects and enhance which is why we are dedicated to providing quality of life both during and after treatment. efficient, convenient cancer care for our patients At CTCA, each patient is served by a while reducing their stress as much as possible. Maurie Markman, MD Julian Schink, MD multidisciplinary team of physicians, nurses, President, Medicine & Science Chief Medical Officer CTCA Comprehensive Cancer Care Network registered dietitians and other care providers. CTCA CTCA hospitals and outpatient care centers are located These teams include individuals with extensive in or near five major U.S. cities: Atlanta, Chicago, A nationally renowned board-certified Dr. Schink brings more than 25 experience in treating cancer. Together they Philadelphia, Phoenix and Tulsa. Each city has an medical oncologist, Dr. Markman years of oncology experience to develop and implement an individualized airport that is serviced by most major airlines. We is President of Medicine and Science and serves his position as Chief Medical Officer at CTCA. treatment plan tailored to each patient’s assist many patients with travel arrangements, on the National Board of Directors at CTCA. Dr. Board-certified in gynecologic oncology as well unique diagnosis and life goals. including lodging accommodations for themselves, Markman has more than 20 years of experience in as obstetrics and gynecology, he is dedicated to For these reasons, patients, physicians, employers their caregivers and families either on-site at our cancer treatment and gynecologic research. caring for patients and advancing the treatment of and insurers can depend on CTCA to offer hospitals or in nearby hotels. For his remarkable achievements in clinical practice gynecologic malignancies. comprehensive, compassionate and truly and oncology research, Dr. Markman was recently Prior to joining CTCA, Dr. Schink held numerous personalized cancer care. HEALTH INSURANCE AND VERIFICATION named by OncLive® as an inductee of the 2018 academic positions, including Vice Chair of CTCA verifies the insurance and benefits of Giants of Cancer Care® recognition program. In obstetrics and gynecology and professor at prospective patients, including in-network 2011, he received the esteemed American Society the University of Wisconsin Medical School, and out-of-network benefits, deductibles, plan of Clinical Oncology (ASCO) Statesman Award. and subsequently an endowed professorship coverage percentages and co-pays. The verification Presented annually, the Statesman Award recognizes at Northwestern University Feinberg School of process typically takes less than 24 hours. CTCA individual ASCO members who have shown Medicine as the John and Ruth Brewer Chair in financial counselors are also available to patients extraordinary volunteer service, dedication and Gynecology and Cancer Research. and caregivers should they need assistance with commitment to ASCO, their hospital community Published in numerous medical journals and more the financial arrangements for their care. and the patients they serve for at least 20 years. than 125 publications dedicated to oncology and CTCA maintains contracts with many major Prior to joining CTCA, Dr. Markman served as the women’s health, Dr. Schink has also authored more national and regional insurance companies, Vice President for Clinical Research and Chairman of than 10 chapters in oncology textbooks, focusing employers and other health care companies that the Department of Gynecologic Medical Oncology much of his academic work on gestational have approved patient access to CTCA hospitals. We at MD Anderson Cancer Center in Houston. Prior trophoblastic disease. He served as principal treat patients who have both in-network and out-of- to that, he served as Chair of the Department of investigator and co-investigator for many clinical network benefits with these carriers. Hematology/Oncology and Director of the Taussig trials responsible for improving and expanding Cancer Center at the Cleveland Clinic Foundation, cancer treatment options. and Vice Chair of the Department of Medicine at Additionally, Dr. Schink serves as Chief of Memorial Sloan-Kettering Cancer Center in New York. Gynecologic Oncology for CTCA, Medical Director Dr. Markman received his MD from New York of Gynecologic and Medical Oncology and Senior University. Vice President of Clinical Affairs for CTCA Chicago. Dr. Schink received his MD from The University of Texas at San Antonio. 4 CTCA Patient Treatment Results 2019 | 2020 ABOUT THIS REPOR T 5
CTCA Patient Demographics CTCA Patient Demographics JULY 1, 2017 - JUNE 30, 2018 JULY 1, 2017 - JUNE 30, 2018 New Patients BY GENDER New Patients BY AGE GROUP Analytic and Non-Analytic Analytic and Non-Analytic Patient demographics are based on data provided by the tumor registry from July 1, 2017 - June 30, 2018. 90+ 15 Types New Patients1 ANALYTIC AND Cancer Types BY STAGE New New Patients Patients11 ANALYTIC ANALYTIC AND AND Cancer Cancer Types BYBY STAGE STAGE New NewPatients PatientsBY BY GENDER 2GENDER New New Patients Patients BY BY AGE AGE GROUP GROUP 4,080 NONANALYTIC22 NONANALYTIC 80-89 Analytic 224 AnalyticPatients PatientsOnly Only 44%% 176 176 NONANALYTIC Analytic Analyticand andNon-Analytic Non-Analytic Analytic Analytic Patients Analyticand Only andNon-Analytic Non-Analytic 4% 176 44% 1,067 Unknown Male 70-79 261 261 77%% Unknown Unknown 261 7% 9,192 60-69 2,862 5,150 3% 119 5,150 5,150 5,112 N/A N/A 50-59 33%% 119 119 3,021 4,080 4,080 90+ 90+ N/A 15 15 56 56%% 56% 1,383 Non- 56% 80-89 80-89 1,184 29% 224 224 Stage 0 Non- Non- 1,1,1184 40-49 84 29 Stage Stage00 44 44%% 4,042 1,067 1,067 20% Analytic Analytic 4,042 4,042 Female 30-39 29 482 %% 20 20%% 807 807 Analytic Male Male 44% 70-79 70-79 Stage IV 807 Patients Patients 44 44%% Analytic Analytic Stage StageIV 18-29 IV 138 Patients 9,192 9,192 Analytic 60-69 60-69 2,862 2,862 Stage 1 3,021 3,021 Patients Patients 0 Stage Stage11 500 1000 1500 2000 2500 3000 56 56%% 5,112 5,112 Patients 50-59 50-59 694 17% 20% 801 694 694 17 17%% 20 20%% 801 801 Female Female 40-49 40-49 Stage III 30-39 30-39 482 482 1,383 1,383 Stage StageIIIIII Stage II Stage StageIIII 18-29 18-29 138 138 00 500 500 1000 1000 1500 1500 2000 2000 2500 2500 3000 3000 New Patients BY CANCER TYPE 3 New Patients BY STATE OR TERRITORY New New Patients Patients Analytic BY BY STATE STATE and Non-Analytic OR OR TERRITORY Patients TERRITORY Analytic and Non-Analytic Analytic Analyticand andNon-Analytic Non-Analytic 3000 2,879 WA WA WA New 53 BY NewPatients Patients BY CANCER TYPE33 ND CANCER TYPE ME 53 53 30.2% ME ME MT 10 2500 MT MT ND ND 10 10 Analytic Analyticand andNon-Analytic Non-AnalyticPatients Patients 28 20 OR OR 28 28 2,276 2,276 20 20 VT VT99 4,612 4,612 OR 2,276 MN VT 9 4,612 NH 6 2,088 MN MN NH66 NH 43 ID SD 55 WI NY MA 14 2000 43 43 ID ID SD SD 55 55 NY NY MA14 MA 14 3000 3000 41 172 21.9% 41 41 23 23 WI WI 210 210 172 172 RI22 RI WY 23 210 MI 2,879 2,879 RI 2 CT 29 WY WY MI MI 13 253 PA30.2 IA 30.2%% 2500 628NV 13 13 253 253 PA PA CT CT2929 NE NJ 180 1500 IA IA 753 628 628NV NV NE NE 74 74 753 753 NJ NJ 180 180 2500 45 74 IL IN OH DE 53 62 62 UT UT 1,06645 45 1,132 IL 825 IL ININ OH 825% 250 250 OH 215 215 DE DE53 MD 53 MD156 156 2,08862 2,088 UT 14 C0 825 250 215 WV VA MD 156 1000 14 14 C0 C0 11.9 WV WV VA VA 2000 CA 2000 21.9 56 KS MO KY 43 178 DC 12 11.2% KS 21.9 1 CA CA 207 207 647 56 56 KS 546MO MO KY KY 43 43 178 178 1 1 DC DC1212 207 %% 1,018 113 223 85 500 1,018 1,018 6.8% 166 314 113 113 223 223 85 85 269 188 NC NC 1500 1500 NC 324 230 5.7% 2.0% 324 324 AZ OK TN 230 AZ 1.7% AZ 3.3% OK OK TN TN230 230 2.8% 398 NM 731 AR 1,132 1,132 SC 0 398 398 NM NM 2.4 731 731% AR AR SC SC 51 1,066 1,066 159 AL GA 193 51 51 1000 1000 950 950 159 159 MS AL MS AL GA GA 193 193 950 647 647 11.2 11.2%% MS 11.9 11.9%% 103 407 1,158 407 1,158 103 407 103 1,158 TX 546 546 LA TX TX 166 166 314 314 269 188 188 te 6.8 6.8%% al LA LA ian ic 500 500 417 h 269 y 5.7%82 st al n r ng 230 230 5.7 ge ne ac he at ta % lo ct ea 417 417 ar 82 82 re os om Lu Co Kid ha 1.7 1.7%% 2.0 2.0%%FL Ot Re Ov Br nc Pr 3.3 3.3%% 2.8 2.8%% op FL FL AK 2.4 2.4%% St 314 Pa Es AK AK 314 314 00 25 25 25 1 The overall patient population includes patients evaluated at CTCA. Non-analytic patients are those who received OTHER/UNKNOWN 29 tee all riiaan n OTHER/UNKNOWN OTHER/UNKNOWN 29 29 at CTCA due to progressive or tiicc acch h geea neey y asst t taal l onn err sttaat ngg across all CTCA hospitals, including those who received subsequent cancer treatment thhe eaat ollo ecct reea LLuun haag idn ma vaar crre roos toom CCo KKid OOt RRe OOv BBr non-cancer directed therapy or received palliative care only. recurrent disease. opph annc PPr SSt EEsso PPa 2 Analytic patients are those who are diagnosed and/or 3 Includes 9,192 patients of which 353 had multiple primary HI HI HIof cancer treatment VI 22 PR 1 received all or part of their first course 22sites, equating to 9,525 VI22 VI PR11primary cancers. PR 23 23 23 6 CTCA Patient Treatment Results 2019 | 2020 ABOUT THIS REPOR T 7
About this Report Our Length of Life Results 2 Our Quality of Life Results Our Patient Experience Results Our Patient Safety and Quality Results Our Clinical Leadership Our Research Publications
Stacy F. Our Length of Life Results LU N G C A N C E R SECTION 2 SPOTLIGHT CTCA Chicago “My medical oncologist talked to Independent Researchers’ Letter • Bert Spilker & Associates, LLC, an independent health care consulting firm, me about immunotherapy. I hadn’t Dear Reader: produced the study design for the analyses We analyzed the data provided by Cancer Treatment and interpretation of the data. heard of this option before. I soon Centers of America® (CTCA) and the National Cancer Institute’s Surveillance, Epidemiology, and End • After reviewing data sources, the National found out that immunotherapy Cancer Institute’s Surveillance, Epidemiology, Results (SEER) Program database from 2000 through uses the body’s immune system 2015 for the purpose of compiling survival rates for and End Results (SEER) comparison sample eleven (11) cancers of interest. Our efforts employed was chosen by matching basic characteristics to fight cancer cells. I did about six the statistical guidelines that govern these types of (e.g., categories or range of values) on several analyses by leading practitioners. Although the lack of the most important factors that affect weeks of immunotherapy, and I of direct comparability of the two data sets imposes survival outcomes. immediately knew it was working. certain limitations on the interpretation of the results as stated elsewhere in this publication, we believe • The analyses of both the CTCA and SEER It’s amazing to me that my own the analyses provide an accurate representation of samples only include cancer patients with survival rates for CTCA® patients. one of 11 cancer types whose initial diagnosis body can be used to identify and occurred between 2000 and 2015. The graphs Sincerely, on the following pages illustrate the findings. fight the bad cells. I am still in Bert Spilker, PhD, MD Chengjie Xiong, PhD active treatment and continuing immunotherapy.” BERT SPILKER, PHD, MD Bert Spilker, PhD, MD, is the founder of Bert Spilker & Associates, LLC (BS&A), a health care consulting company working with more than 100 health care clients and contracting with over 150 experts on a variety of research No case is typical. You should not expect areas of specialization. to experience these results. Prior to forming BS&A, Dr. Spilker served as the Senior Vice President of Scientific and Regulatory Affairs for Pharmaceutical Research and Manufacturers of America (PhRMA) based in Washington, D.C. where he represented the U.S. pharmaceutical industry both nationally and internationally. Dr. Spilker also served as President and co-founder of Orphan Medical, Inc., a pharmaceutical company that developed and marketed medical products for patients with orphan/rare diseases. He currently serves as Clinical Professor of Pharmacy Practice at the University of Minnesota and Adjunct Professor of Medicine and Clinical Professor of Pharmacy at the University of North Carolina at Chapel Hill. Dr. Spilker completed his medical training in pharmacology and internal medicine at Cornell Medical College, State University of New York (Downstate Medical Center), University of California at San Francisco, University of Miami Medical School (PhD to MD Program) and Brown University Medical School. CHENGJIE XIONG, PHD, MS Chengjie Xiong, PhD, MS, studies novel statistical design of experiments and clinical trials, linear and nonlinear mixed models, longitudinal data analysis, survival analysis and reliability, diagnostic accuracy, advanced meta-analysis, categorical data analysis, order restricted statistical inferences, and their applications in medicine, public health, biology, education and engineering. Dr. Xiong remains active in interdisciplinary research and has provided statistical consulting for academia, private industries and government agencies across the country, including directing the database management and statistical analyses for several National Institutes of Health (NIH) funded projects. He received a BS in Mathematics from Xiangtan University (China), an MS in Applied Mathematics from Peking University (China), and a PhD in Statistics from Kansas State University. OUR LENGTH OF LIFE RESULTS 9
METHODOLOGY For both the CTCA and SEER samples, only cancer The survival curve for each cancer type (defined patients whose initial diagnosis occurred between as the probability of a cancer patient’s survival as 2000 and 2015 were analyzed. Cancer cases with a function of time from the initial diagnosis) was missing information on either the date of initial estimated by the Kaplan-Meier nonparametric diagnosis or date of last contact were deleted product-limit estimator. 1 Three statistical tests were from the CTCA database because the survival then used to compare the survival curves between time or censoring time for such patients could the CTCA database and the SEER database. not be computed. Cancer patients with missing Two of these tests, the log rank test and Wilcoxon SEER Summary Stages were also excluded from test, are nonparametric and thus, valid to compare the analyses. For patients with multiple cancers survival curves that have any shapes.1 These tests are in the SEER and CTCA databases, only the first or different, however, in their sensitivity (or the power) primary cancer diagnosed was used for the survival to detect survival differences. The log rank test is comparisons. Patients with a histologic code considered the most sensitive or powerful when the (ICD-O-3) between 9590 and 9989 were excluded risk or the hazard of death between CTCA and SEER Statistical Methodology from the analyses because these histologic types samples is approximately proportional, whereas the are generally not included by SEER for any non- Wilcoxon test tends to be more sensitive when the hematopoietic cancer types. Patients who did not ratio of hazards of death is higher at earlier times DATA SELECTION receive treatment from CTCA were also excluded than at later ones. The third test, the likelihood ratio Two databases were considered for this study. The SEER database was selected to conduct these from the analyses. test, is the most restrictive of the three in the sense The National Cancer Institute’s Surveillance, analyses because of its comprehensive content The survival outcomes from the SEER database were that it is appropriate to use only for special survival Epidemiology, and End Results (SEER) Program and access to patient-level data (and because provided by the SEER Limited-Use Data File as the curves (called exponential distributions) whose database and the National Cancer Database (NCDB). of restrictions imposed on the use of the NCDB number of completed months. These numbers were hazards of death are constant across time.2 The SEER database is an authoritative data set database for comparative analysis and external then converted to the number of years by dividing Ninety-five percent confidence interval (95% CI) created for use as an epidemiological tool to reporting purposes). the number of total months by 12. Although the estimates for the individual survival rates, as well monitor the incidence and mortality of cancer The SEER comparison sample was chosen by exact dates for the initial diagnosis and death as the difference in survival rates between the in the United States. SEER collects patient the categories in categorical factors (e.g., cancer were available in the CTCA database, the CTCA CTCA and SEER samples at specific time points demographics, tumor characteristics and survival stages) with the CTCA cancer cohort and selecting survival outcomes were computed using the same after diagnosis, were based on the estimated data from 17 regional registries throughout the U.S., the overlapping ranges in continuous factors methodology as the SEER database; the number of survival curves and the relevant asymptotic normal representing 28 percent of the U.S. population. (e.g., age at diagnosis) from the CTCA cancer completed months was computed by first dividing distributions. All these analyses were implemented cohort. These factors affect survival outcomes. the exact days from the initial diagnosis to death, or using the standard SAS package of statistical tests The NCDB compiles cancer registry data from last contact for those who remained alive, by 365.24 cancer programs in the U.S. and Puerto Rico, The SEER Limited-Use Database (2016) was used (i.e., SAS/PROC LIFETEST).3 Adjusted analyses were to select the SEER comparison sample. The final (as was done by SEER), then rounding down to the also done (results not shown) using the stratified capturing approximately 75% of newly diagnosed number of completed months, and finally dividing cancers in these areas. It includes data on patient survival analyses included only patients from both log rank test and the Wilcoxon test as well as Cox’s the CTCA and SEER databases whose following the result by 12. For those patients who were still proportional hazards models to compare the characteristics, tumor staging, tumor histology, alive or lost to follow-up at the time of entering the type of first treatment, disease recurrence and cancer characteristics were available from the two survival outcomes between the CTCA and SEER databases: SEER Summary Stages, primary tumor databases, survival time was treated as statistically samples after adjusting for the effects of age at survival using standardized coding definitions. It is censored at the difference between the date of last commonly used to guide quality improvement and sites, cancer histologic types, gender and age at diagnosis, gender (except for breast and prostate initial diagnosis. For example, if a specific SEER contact and the date of initial diagnosis.1 cancers), race, marital status at diagnosis, insurance pursue investigator-initiated research questions. The NCDB provides insight into analytic cancer Summary Stage had only patients in one database, status at diagnosis and year of initial diagnosis. The diagnoses and primary treatments. The main none of these patients was used in the analyses. technical details of these statistical analyses are limitation of the data is that the cohorts are not To match the age at initial diagnosis, the range (i.e., available from CTCA. population-based; they are identified from the minimum and maximum ages) was computed for hospitals at which the patients presented for each sample. Only patients whose age at initial diagnosis fell into the overlap of the two ranges 1 Kalbfleisch JD, Prentice RL. The Statistical Analysis of Failure Time Data. New York: John Wiley, 1980. diagnosis and/or treatment. from the CTCA and SEER samples were included in 2 Lawless JF. Statistical Methods and Methods for Lifetime Data, New York: John Wiley & Sons, Inc., 1982. the comparative survival analyses. 3 SAS Institute Inc., SAS/STAT User’s Guide, Volume 2, Version 6, 1990. Cary, NC, USA. 10 CTCA Patient Treatment Results 2019 | 2020 OUR LENGTH OF LIFE RESULTS 11
Length of Life Results BREAST CANCER The chart below reflects the Cancer Treatment Centers of America® (CTCA) and SEER survival rates for breast cancer patients with distant (metastatic) disease who were diagnosed between 2000 and 2015. It includes estimates of the percentage of breast cancer patients with distant (metastatic) disease who survived for six months to five years after the initial diagnosis, as recorded in the CTCA® and SEER databases. • This analysis included breast cancer patients from CTCA who had primary tumor sites (as coded by ICD-O-2 (1973+)) from C500 to C509, were diagnosed from 2000 to 2015 (including 2000 and 2015) and received at least part of their initial course of treatment at CTCA. All patients included in the analysis were considered analytic patients by CTCA. • Breast cancer patients with distant (metastatic) disease from the SEER database and breast cancer patients with distant (metastatic) disease from the CTCA database were included in the analysis. In addition, the analysis excluded patients whose medical records were missing any of the following information: – SEER Summary Stages – Date of initial diagnosis – Primary tumor sites – Age at initial diagnosis – Cancer histologic types – Gender & Race BREAST CANCER SURVIVAL RATE LIMITATIONS Patients DiagnosedBREAST CANCER(Metastatic) with Distant SURVIVAL Cancer RATE Between 2000-2015 Direct statistical comparisons of survival outcomes between groups of cancer patients have limitations Patients Diagnosed with Distant (Metastatic) Cancer Between 2000-2015 CTCA (n=788) and SEER* (n=64,690) because of the possible confounding effects of other factors cited below and elsewhere in this report. CTCA (n=632) and SEER* (n=38,935) Accordingly, the data appearing in this report should be considered directional, not definitive. 100 First, although a large sample of patients was available from the SEER Program across many geographic 90 94 regions in the U.S., both samples, including the sample from CTCA, are convenience samples. This precludes the assumption of a causal interpretation of the statistical inferences. Second, although some types of 80 86 Percent of Patients matching, as described earlier, were implemented to select the appropriate SEER and CTCA comparison 70 75 76 samples, the distributions of important covariates, such as age at initial diagnosis, gender, race, marital 60 66 69 status at diagnosis, insurance status at diagnosis and year of initial diagnosis, were not exactly the same 62 50 57 56 between the CTCA sample and SEER sample. Hence, even with the adjusted analyses, possible confounding 50 50 of these factors to the analyses and results may not be ruled out. Further, many factors (e.g., household 40 43 45 30 38 39 36 income, mobility, etc.) other than those considered in the analyses and available from the databases may 33 have contributed to the actual survival outcomes. As a result of these factors, the possible confounding of 20 29 26 24 the results of these analyses may not be ruled out. Finally, the survival analyses were based on the statistical 10 comparisons of the rate of death from all possible causes, not solely cancer-specific death. These data are 0 not included in the CTCA data set and, therefore, not available for statistical comparison. 0.5 1 1.5 2 2.5 3 3.5 4 4.5 5 Visit cancercenter.com/ctca-results for further information about the methodology used to calculate the Years (after initial diagnosis) CTCA results and read about the analysis limitations. CTCA SEER *The SEER data represent national results over a large number of institutions and have been included for illustrative purposes. They are not intended to represent a controlled study and/or a perfect analysis of the CTCA data because of variability in the sample sizes of the two databases, the clinical condition(s) of the patients treated and other factors. 12 CTCA Patient Treatment Results 2019 | 2020 OUR LENGTH OF LIFE RESULTS 13
Length of Life Results Length of Life Results COLON CANCER ESOPHAGEAL CANCER The chart below reflects the Cancer Treatment Centers of America® (CTCA) and SEER survival rates for colon The chart below reflects the Cancer Treatment Centers of America® (CTCA) and SEER survival rates for cancer patients with distant (metastatic) disease who were diagnosed between 2000 and 2015. It includes esophageal cancer patients with distant (metastatic) disease who were diagnosed between 2000 and 2015. estimates of the percentage of colon cancer patients with distant (metastatic) disease who survived for six It includes estimates of the percentage of esophageal cancer patients with distant (metastatic) disease who months to five years after the initial diagnosis, as recorded in the CTCA® and SEER databases. survived for six months to five years after the initial diagnosis, as recorded in the CTCA® and SEER databases. • This analysis included colon cancer patients from CTCA who had primary tumor sites (as coded by • This analysis included esophageal cancer patients from CTCA who had primary tumor sites (as coded by ICD-O-2 (1973+)) from C180 to C189, were diagnosed from 2000 to 2015 (including 2000 and 2015) and ICD-O-2 (1973+)) from C150 to C159, were diagnosed from 2000 to 2015 (including 2000 and 2015) and received at least part of their initial course of treatment at CTCA. All patients included in the analysis were received at least part of their initial course of treatment at CTCA. All patients included in the analysis were considered analytic patients by CTCA. considered analytic patients by CTCA. • Colon cancer patients with distant (metastatic) disease from the SEER database and colon cancer patients • Esophageal cancer patients with distant (metastatic) disease from the SEER database and esophageal with distant (metastatic) disease from the CTCA database were included in the analysis. In addition, the cancer patients with distant (metastatic) disease from the CTCA database were included in the analysis. analysis excluded patients whose medical records were missing any of the following information: In addition, the analysis excluded patients whose medical records were missing any of the following information: – SEER Summary Stages – Date of initial diagnosis – Primary tumor sites – Age at initial diagnosis – SEER Summary Stages – Date of initial diagnosis – Cancer histologic types – Gender & Race – Primary tumor sites – Age at initial diagnosis – Cancer histologic types – Gender & Race COLON CANCER SURVIVAL RATE ESOPHAGEAL CANCER SURVIVAL RATE Patients Diagnosed COLON with CANCER SURVIVAL Cancer Distant (Metastatic) RATE Between 2000-2015 ESOPHAGEAL Patients Diagnosed CANCER with Distant SURVIVAL (Metastatic) RATE Cancer Between 2000-2015 Patients Diagnosed with Distant CTCA (n=788) (Metastatic) and SEER* Cancer Between 2000-2015 (n=64,690) Patients Diagnosed CTCA (n=788) and SEER* (n=64,690) 2000-2015 with Distant (Metastatic) Cancer Between CTCA (n=788) and SEER* (n=64,690) CTCA (n=291) and SEER* (n=15,311) 100 100 90 90 80 87 80 Percent of Patients Percent of Patients 70 70 71 60 64 60 64 50 54 50 51 40 44 40 47 40 38 30 34 30 31 28 20 25 20 26 21 20 17 20 10 16 15 15 13 10 16 6 7 5 6 5 6 4 4 4 12 12 13 11 11 8 0 0 8 0.5 1 1.5 2 2.5 3 3.5 4 4.5 5 0.5 1 1.5 2 2.5 3 3.5 4 4.5 5 Years (after initial diagnosis) Years (after initial diagnosis) CTCA SEER CTCA SEER *The SEER data represent national results over a large number of institutions and have been included for illustrative purposes. *The SEER data represent national results over a large number of institutions and have been included for illustrative purposes. They are not intended to represent a controlled study and/or a perfect analysis of the CTCA data because of variability in the They are not intended to represent a controlled study and/or a perfect analysis of the CTCA data because of variability in the sample sizes of the two databases, the clinical condition(s) of the patients treated and other factors. sample sizes of the two databases, the clinical condition(s) of the patients treated and other factors. 14 CTCA Patient Treatment Results 2019 | 2020 OUR LENGTH OF LIFE RESULTS 15
Length of Life Results Length of Life Results KIDNEY CANCER NON–SMALL CELL LUNG CANCER The chart below reflects the Cancer Treatment Centers of America® (CTCA) and SEER survival rates for kidney The chart below reflects the Cancer Treatment Centers of America® (CTCA) and SEER survival rates for cancer patients with distant (metastatic) disease who were diagnosed between 2000 and 2015. It includes non-small cell lung cancer patients with distant (metastatic) disease who were diagnosed between 2000 estimates of the percentage of kidney cancer patients with distant (metastatic) disease who survived for six and 2015. It includes estimates of the percentage of non-small cell lung cancer patients with distant (meta- months to five years after the initial diagnosis, as recorded in the CTCA® and SEER databases. static) disease who survived for six months to five years after the initial diagnosis, as recorded in the CTCA® and SEER databases. • This analysis included kidney cancer patients from CTCA who had primary tumor site (as coded by ICD-O-2 (1973+)) of C649, were diagnosed from 2000 to 2015 (including 2000 and 2015) and received at • This analysis included non-small cell lung cancer patients from CTCA who had primary tumor sites (as least part of their initial course of treatment at CTCA. All patients included in the analysis were considered coded by ICD-O-2 (1973+)) from C340 to C343 or from C348 to C349, were diagnosed from 2000 to analytic patients by CTCA. 2015 (including 2000 and 2015) and received at least part of their initial course of treatment at CTCA. All • Kidney cancer patients with distant (metastatic) disease from the SEER database and kidney cancer patients patients included in the analysis were considered analytic patients by CTCA. with distant (metastatic) disease from the CTCA database were included in the analysis. In addition, the • Non-small cell lung cancer patients with distant (metastatic) disease from the SEER database and non-small analysis excluded patients whose medical records were missing any of the following information: cell lung cancer patients with distant (metastatic) disease from the CTCA database were included in the analysis. In addition, the analysis excluded patients whose medical records were missing any of the – SEER Summary Stages – Date of initial diagnosis following information: – Primary tumor sites – Age at initial diagnosis – SEER Summary Stages – Date of initial diagnosis – Cancer histologic types – Gender & Race – Primary tumor sites – Age at initial diagnosis – Cancer histologic types – Gender & Race KIDNEY CANCER SURVIVAL RATE NONSMALL CELL LUNG CANCER SURVIVAL RATE KIDNEY CANCER(Metastatic) SURVIVALCancerRATE Between 2000-2015 Patients Diagnosed with Distant PatientsNON-SMALL Diagnosed withCELL LUNG CANCER SURVIVAL RATE Distant (Metastatic) Cancer Between 2000-2015 Patients Diagnosed with Distant CTCA (n=788) (Metastatic) and SEER* Cancer Between 2000-2015 (n=64,690) Patients Diagnosed with Distant (Metastatic) Cancer Between 2000-2015 CTCA (n=788) and SEER* (n=64,690) CTCA (n=228) and SEER* (n=20,824) CTCA (n=2,336) and SEER* (n=283,704) 100 100 90 90 80 80 Percent of Patients Percent of Patients 70 70 70 68 60 60 50 50 51 49 40 40 47 30 36 37 30 39 34 20 27 29 22 25 20 24 25 18 21 19 19 10 16 14 17 16 15 10 16 15 7 6 5 8 7 12 11 10 12 12 4 4 9 10 0 0 0.5 1 1.5 2 2.5 3 3.5 4 4.5 5 0.5 1 1.5 2 2.5 3 3.5 4 4.5 5 Years (after initial diagnosis) Years (after initial diagnosis) CTCA SEER CTCA SEER *The SEER data represent national results over a large number of institutions and have been included for illustrative purposes. *The SEER data represent national results over a large number of institutions and have been included for illustrative purposes. They are not intended to represent a controlled study and/or a perfect analysis of the CTCA data because of variability in the They are not intended to represent a controlled study and/or a perfect analysis of the CTCA data because of variability in the sample sizes of the two databases, the clinical condition(s) of the patients treated and other factors. sample sizes of the two databases, the clinical condition(s) of the patients treated and other factors. 16 CTCA Patient Treatment Results 2019 | 2020 OUR LENGTH OF LIFE RESULTS 17
Length of Life Results Length of Life Results SMALL CELL LUNG CANCER OVARIAN CANCER The chart below reflects the Cancer Treatment Centers of America® (CTCA) and SEER survival rates for small The chart below reflects the Cancer Treatment Centers of America® (CTCA) and SEER survival rates for ovarian cell lung cancer patients with distant (metastatic) disease who were diagnosed between 2000 and 2015. It cancer patients with distant (metastatic) disease who were diagnosed between 2000 and 2015. It includes includes estimates of the percentage of small cell lung cancer patients with distant (metastatic) disease who estimates of the percentage of ovarian cancer patients with distant (metastatic) disease who survived for six survived for six months to five years after the initial diagnosis, as recorded in the CTCA® and SEER databases. months to five years after the initial diagnosis, as recorded in the CTCA® and SEER databases. • This analysis included small cell lung cancer patients from CTCA who had primary tumor sites (as coded • This analysis included ovarian cancer patients from CTCA who had primary tumor site (as coded by by ICD-O-2 (1973+)) from C340 to C343 or from C348 to C349, were diagnosed from 2000 to 2015 ICD-O-2 (1973+)) of C569, were diagnosed from 2000 to 2015 (including 2000 and 2015) and received at (including 2000 and 2015) and received at least part of their initial course of treatment at CTCA. All least part of their initial course of treatment at CTCA. All patients included in the analysis were considered patients included in the analysis were considered analytic patients by CTCA. analytic patients by CTCA. • Small cell lung cancer patients with distant (metastatic) disease from the SEER database and small cell • Ovarian cancer patients with distant (metastatic) disease from the SEER database and ovarian cancer lung cancer patients with distant (metastatic) disease from the CTCA database were included in the patients with distant (metastatic) disease from the CTCA database were included in the analysis. In analysis. In addition, the analysis excluded patients whose medical records were missing any of the addition, the analysis excluded patients whose medical records were missing any of the following following information: information: – SEER Summary Stages – Date of initial diagnosis – SEER Summary Stages – Date of initial diagnosis – Primary tumor sites – Age at initial diagnosis – Primary tumor sites – Age at initial diagnosis – Cancer histologic types – Gender & Race – Cancer histologic types – Gender & Race SMALL CELL LUNG CANCER SURVIVAL RATE OVARIAN CANCER SURVIVAL RATE SMALL CELL LUNG CANCER SURVIVAL RATE OVARIAN CANCER SURVIVAL RATE Patients Diagnosed with Distant (Metastatic) Cancer Between 2000-2015 Patients Diagnosed with Distant (Metastatic) Cancer Between 2000-2015 Patients Diagnosed with Distant (Metastatic) Cancer Between 2000-2015 Patients Diagnosed with Distant (Metastatic) Cancer Between 2000-2015 CTCA (n=788) and SEER* (n=64,690) CTCA (n=349) and SEER* (n=56,817) CTCA (n=788) and SEER* (n=64,690) CTCA (n=237) and SEER* (n=40,893) 100 100 90 90 95 80 80 88 79 78 Percent of Patients Percent of Patients 70 76 70 71 60 60 63 66 61 50 50 56 54 49 49 40 45 40 43 43 40 38 38 30 30 34 32 30 27 20 20 21 21 10 7 5 6 4 4 4 4 4 10 11 13 9 3 3 3 3 0 0 0.5 1 1.5 2 2.5 3 3.5 4 4.5 5 0.5 1 1.5 2 2.5 3 3.5 4 4.5 5 Years (after initial diagnosis) Years (after initial diagnosis) CTCA SEER CTCA SEER *The SEER data represent national results over a large number of institutions and have been included for illustrative purposes. *The SEER data represent national results over a large number of institutions and have been included for illustrative purposes. They are not intended to represent a controlled study and/or a perfect analysis of the CTCA data because of variability in the They are not intended to represent a controlled study and/or a perfect analysis of the CTCA data because of variability in the sample sizes of the two databases, the clinical condition(s) of the patients treated and other factors. sample sizes of the two databases, the clinical condition(s) of the patients treated and other factors. 18 CTCA Patient Treatment Results 2019 | 2020 OUR LENGTH OF LIFE RESULTS 19
Length of Life Results Length of Life Results PANCREATIC CANCER PROSTATE CANCER The chart below reflects the Cancer Treatment Centers of America® (CTCA) and SEER survival rates for The chart below reflects the Cancer Treatment Centers of America® (CTCA) and SEER survival rates for pancreatic cancer patients with distant (metastatic) disease who were diagnosed between 2000 and 2015. prostate cancer patients with distant (metastatic) disease who were diagnosed between 2000 and 2015. It includes estimates of the percentage of pancreatic cancer patients with distant (metastatic) disease who It includes estimates of the percentage of prostate cancer patients with distant (metastatic) disease who survived for six months to five years after the initial diagnosis, as recorded in the CTCA® and SEER databases. survived for six months to five years after the initial diagnosis, as recorded in the CTCA® and SEER databases. • This analysis included pancreatic cancer patients from CTCA who had primary tumor sites (as coded by • This analysis included prostate cancer patients from CTCA who had primary tumor site (as coded by ICD-O-2 (1973+)) from C250 to C254 or from C257 to C259, were diagnosed from 2000 to 2015 (including ICD-O-2 (1973+)) of C619, were diagnosed from 2000 to 2015 (including 2000 and 2015) and received at 2000 and 2015) and received at least part of their initial course of treatment at CTCA. All patients included least part of their initial course of treatment at CTCA. All patients included in the analysis were considered in the analysis were considered analytic patients by CTCA. analytic patients by CTCA. • Pancreatic cancer patients with distant (metastatic) disease from the SEER database and pancreatic cancer • Prostate cancer patients with distant (metastatic) disease from the SEER database and prostate cancer patients with distant (metastatic) disease from the CTCA database were included in the analysis. In addition, patients with distant (metastatic) disease from the CTCA database were included in the analysis. In addition, the analysis excluded patients whose medical records were missing any of the following information: the analysis excluded patients whose medical records were missing any of the following information: – SEER Summary Stages – Date of initial diagnosis – SEER Summary Stages – Date of initial diagnosis – Primary tumor sites – Age at initial diagnosis – Primary tumor sites – Age at initial diagnosis – Cancer histologic types – Gender & Race – Cancer histologic types – Gender & Race PANCREATIC CANCER SURVIVAL RATE PROSTATE CANCER SURVIVAL RATE PANCREATIC CANCER Patients Diagnosed with Distant SURVIVAL (Metastatic) RATEBetween 2000-2015 Cancer PROSTATE CANCER Patients Diagnosed with Distant SURVIVAL (Metastatic) RATE Between 2000-2015 Cancer Patients Diagnosed with Distant (Metastatic) Cancer Between 2000-2015 Patients Diagnosed with Distant (Metastatic) Cancer Between 2000-2015 CTCA (n=788) and SEER* (n=64,690) CTCA (n=788) and SEER* (n=64,690) CTCA (n=1,555) and SEER* (n=64,946) CTCA (n=321) and SEER* (n=34,487) 100 100 90 90 97 90 80 80 85 82 Percent of Patients Percent of Patients 70 70 73 74 60 60 65 58 61 58 50 50 52 49 40 40 45 43 30 30 39 37 32 34 35 28 31 20 20 27 25 10 18 8 7 10 14 11 6 4 6 3 5 3 4 3 3 2 3 2 0 0 0.5 1 1.5 2 2.5 3 3.5 4 4.5 5 0.5 1 1.5 2 2.5 3 3.5 4 4.5 5 Years (after initial diagnosis) Years (after initial diagnosis) CTCA SEER CTCA SEER *The SEER data represent national results over a large number of institutions and have been included for illustrative purposes. *The SEER data represent national results over a large number of institutions and have been included for illustrative purposes. They are not intended to represent a controlled study and/or a perfect analysis of the CTCA data because of variability in the They are not intended to represent a controlled study and/or a perfect analysis of the CTCA data because of variability in the sample sizes of the two databases, the clinical condition(s) of the patients treated and other factors. sample sizes of the two databases, the clinical condition(s) of the patients treated and other factors. 20 CTCA Patient Treatment Results 2019 | 2020 OUR LENGTH OF LIFE RESULTS 21
Length of Life Results Length of Life Results RECTAL CANCER STOMACH CANCER The chart below reflects the Cancer Treatment Centers of America® (CTCA) and SEER survival rates for rectal The chart below reflects the Cancer Treatment Centers of America® (CTCA) and SEER survival rates for cancer patients with distant (metastatic) disease who were diagnosed between 2000 and 2015. It includes stomach cancer patients with distant (metastatic) disease who were diagnosed between 2000 and 2015. estimates of the percentage of rectal cancer patients with distant (metastatic) disease who survived for six It includes estimates of the percentage of stomach cancer patients with distant (metastatic) disease who months to five years after the initial diagnosis, as recorded in the CTCA® and SEER databases. survived for six months to five years after the initial diagnosis, as recorded in the CTCA® and SEER databases. • This analysis included rectal cancer patients from CTCA who had primary tumor site (as coded by ICD-O-2 • This analysis included stomach cancer patients from CTCA who had primary tumor sites (as coded by (1973+)) of C209, were diagnosed from 2000 to 2015 (including 2000 and 2015) and received at least part ICD-O-2 (1973+)) from C160 to C169, were diagnosed from 2000 to 2015 (including 2000 and 2015) and of their initial course of treatment at CTCA. All patients included in the analysis were considered analytic received at least part of their initial course of treatment at CTCA. All patients included in the analysis were patients by CTCA. considered analytic patients by CTCA. • Rectal cancer patients with distant (metastatic) disease from the SEER database and rectal cancer patients • Stomach cancer patients with distant (metastatic) disease from the SEER database and stomach cancer with distant (metastatic) disease from the CTCA database were included in the analysis. In addition, the patients with distant (metastatic) disease from the CTCA database were included in the analysis. In addition, analysis excluded patients whose medical records were missing any of the following information: the analysis excluded patients whose medical records were missing any of the following information: – SEER Summary Stages – Date of initial diagnosis – SEER Summary Stages – Date of initial diagnosis – Primary tumor sites – Age at initial diagnosis – Primary tumor sites – Age at initial diagnosis – Cancer histologic types – Gender & Race – Cancer histologic types – Gender & Race RECTAL CANCER SURVIVAL RATE STOMACH CANCER SURVIVAL RATE Patients Diagnosed with CANCER RECTAL SURVIVAL Cancer Distant (Metastatic) RATE Between 2000-2015 STOMACH CANCER Patients Diagnosed with Distant SURVIVAL (Metastatic) RATE Between 2000-2015 Cancer Patients Diagnosed with Distant (Metastatic) Cancer Between 2000-2015 Patients Diagnosed with Distant (Metastatic) Cancer Between 2000-2015 CTCA (n=788) and SEER* (n=64,690) CTCA (n=788) and SEER* (n=64,690) CTCA (n=243) and SEER* (n=15,179) CTCA (n=372) and SEER* (n=22,990) 100 100 90 90 80 88 80 77 Percent of Patients Percent of Patients 70 74 70 60 60 66 50 59 59 50 40 47 48 40 44 30 37 39 30 34 20 29 28 20 25 24 20 20 19 16 10 15 16 13 14 13 12 10 11 11 6 7 5 6 4 5 5 4 9 9 3 3 0 0 0.5 1 1.5 2 2.5 3 3.5 4 4.5 5 0.5 1 1.5 2 2.5 3 3.5 4 4.5 5 Years (after initial diagnosis) Years (after initial diagnosis) CTCA SEER CTCA SEER *The SEER data represent national results over a large number of institutions and have been included for illustrative purposes. *The SEER data represent national results over a large number of institutions and have been included for illustrative purposes. They are not intended to represent a controlled study and/or a perfect analysis of the CTCA data because of variability in the They are not intended to represent a controlled study and/or a perfect analysis of the CTCA data because of variability in the sample sizes of the two databases, the clinical condition(s) of the patients treated and other factors. sample sizes of the two databases, the clinical condition(s) of the patients treated and other factors. 22 CTCA Patient Treatment Results 2019 | 2020 OUR LENGTH OF LIFE RESULTS 23
About this Report Our Length of Life Results Our Quality of Life Results 3 Our Patient Experience Results Our Patient Safety and Quality Results Our Clinical Leadership Our Research Publications
Scott D. Our Quality of Life Results CO LO R E C TA L C A N C E R SECTION 3 SPOTLIGHT CTCA Atlanta Assessment Background and Methodology • CTCA measures and intervenes on “My oncologist was caring and 27 different indicators of quality of passionate about us working life (symptoms and activities of daily Cancer Treatment Centers of America® (CTCA) was life) for treating patients. as a team to treat and fight among the first U.S. cancer hospitals to use quality of life metrics as part of its routine assessment of patient • Between July 1, 2017 and June 30, my cancer. Most importantly, well-being and quality of care. Research demonstrates 2019, more than 8,692 patients he listened to me. I learned Patient Self-Reported Outcome (PSRO) data are a completed both baseline and valuable part of a patient’s treatment plan. Several return self-assessments. that cancer affects the whole studies validate the potential of routine assessment data in improving both the precision and degree of patient- • Graphs on pages 27-31 reflect a person, not just the organ(s), change in score for patients by centered care – making sure the right care is delivered and CTCA has offerings to help. to the right patients at the right time. The benefits cancer type who self-reported at of PSRO data not only include better health-related least one symptom as severe at I took advantage of nutrition, baseline in comparison to their quality of life and fewer emergency room visits, but also return visit. emotional and psychological improvements in health service outcomes and survival.1,2,3 support, and acupuncture.” CTCA® patients self-report their symptoms and quality • Graphs on pages 32 and 33 reflect of life concerns as part of our patient evaluation CTCA aggregate and facility patient process. This process includes a symptom assessment, self-reported outcome data for five called the Symptom Inventory Tool (SIT), that patients (5) key areas across cancer types. complete in correspondence with their treatment cycle, not more frequently than every 21 days. Upon arrival, patients complete the electronically administered SIT using a tablet computer. CTCA team members utilize these results as part of their patient assessment and evaluation process. These two complementary processes (patient self-assessment and reflection, and analyzing the data as a starting point for discussion) help CTCA care teams readily identify when patients may benefit from referral and/or more directed intervention to help them cope with their symptoms, side effects and quality of life concerns. The data also exist real-time within the electronic health record. More than 94 percent of patients voluntarily participate in the SIT assessments. 1 Basch E, Deal AM, Kris MG, et al: Symptom monitoring with patient-reported outcomes during routine cancer treatment: A randomized controlled trial. J Clin Oncol 10.1200/JCO.2015.63.0830. 2 Jensen R, Snyder CF: PRO-cision Medicine: Personalizing Patient Care Using Patient-Reported Outcomes. J Clin Oncol 10.1200/ JCO.2015.63.0830. 3 Snyder CF, Herman JM, White SM, et al: When using patient- reported outcomes in clinical practice, the measure matters: A randomized controlled trial. J Oncol Pract 10:e299-e306, 2014. OUR QUALIT Y OF LIFE RESULTS 25
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