WHAT CITIES AND TOWNS SHOULD KNOW DURING THE COVID-19 PANDEMIC - Joe Thompson, MD, MPH

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WHAT CITIES AND TOWNS SHOULD KNOW DURING THE COVID-19 PANDEMIC - Joe Thompson, MD, MPH
WHAT CITIES AND TOWNS
SHOULD KNOW DURING THE
COVID-19 PANDEMIC
Joe Thompson, MD, MPH
President and CEO, ACHI
Professor, UAMS Colleges of Medicine and Public Health

04.15.2021
WHAT CITIES AND TOWNS SHOULD KNOW DURING THE COVID-19 PANDEMIC - Joe Thompson, MD, MPH
COVID-19 IN THE UNITED STATES

                                                                                   At least
                                                                               31,400,000
                                                                               confirmed cases

                                                                                   At least
                                                                                564,000
                                                                                reported deaths

Sources: Washington Post and Johns Hopkins University, as of April 15, 2021.
WHAT CITIES AND TOWNS SHOULD KNOW DURING THE COVID-19 PANDEMIC - Joe Thompson, MD, MPH
COVID-19 IN THE UNITED STATES: DAILY CASES

Source: New York Times, April 14, 2021 (using data from state, county and regional health department reports); www.nytimes.com/interactive/2020/us/coronavirus-us-cases.html
WHAT CITIES AND TOWNS SHOULD KNOW DURING THE COVID-19 PANDEMIC - Joe Thompson, MD, MPH
JHU COVID-19 DATA: NEW CASES SPREAD

                                                                                                   April 13, 2021

Sources: Johns Hopkins Coronavirus Resource Center, from Data in Motion published April 14, 2021
WHAT CITIES AND TOWNS SHOULD KNOW DURING THE COVID-19 PANDEMIC - Joe Thompson, MD, MPH
WHAT CITIES AND TOWNS SHOULD KNOW DURING THE COVID-19 PANDEMIC - Joe Thompson, MD, MPH
DAILY CONFIRMED NEW CASES, 7-DAY MOVING AVG

Source: Johns Hopkins University Coronavirus Research Center, www.coronavirus.jhu.edu/data/new-cases, retrieved April 14, 2021
WHAT CITIES AND TOWNS SHOULD KNOW DURING THE COVID-19 PANDEMIC - Joe Thompson, MD, MPH
EUROPEAN COUNTRIES BRING BACK RESTRICTIONS
o France entered third national lockdown on April 3

o Spain introduced new rules last month requiring masks in
  outdoor public spaces

o Poland closed non-essential shops, hotels, and other facilities
  last month

o After re-entering lockdown in January, U.K. slowly easing out

Sources: France and Poland increase lockdown measures as infections surge. BBC. March 20, 2021; UK to ease lockdown next week, will test vaccine passports. AP. April 5, 2021;
How Europe's lockdowns could affect holidays from restrictions to face mask rules. The Daily Mirror, April 6, 2021.
WHAT CITIES AND TOWNS SHOULD KNOW DURING THE COVID-19 PANDEMIC - Joe Thompson, MD, MPH
COVID-19 IN ARKANSAS
                                                                As of April 14

                                                        Cumulative Cases: 332,666
                                                         Total Active Cases: 1,715

                                                            Hospitalized: 151
                                                            On Ventilators: 20
                                        Daily Active
                                        Cases per 1K
                                                           Total Deaths: 5,680
                                        as of 4/14/21

Source: Arkansas Department of Health
WHAT CITIES AND TOWNS SHOULD KNOW DURING THE COVID-19 PANDEMIC - Joe Thompson, MD, MPH
COVID-19 POSITIVE TESTS SINCE SEPTEMBER

Source: ACHI analysis of Arkansas Department of Health data.
WHAT CITIES AND TOWNS SHOULD KNOW DURING THE COVID-19 PANDEMIC - Joe Thompson, MD, MPH
Image: Picspree
COVID-19 HOSPITALIZATIONS IN ARK. PER DAY
1400

1300

1200
              Total of “currently hospitalized”
1100          each day since Sept. 1, 2020
1000

 900

 800

 700

 600

 500

 400

 300

 200

 100

   0
       9/1   9/8 9/15 9/22 9/29 10/6 10/1310/2010/27 11/3 11/1011/1711/24 12/1 12/8 12/1512/2212/29 1/5 1/12 1/19 1/26 2/2   2/9 2/16 2/23 3/2   3/9 3/16 3/23 3/30 4/6 4/13

Source: Arkansas Department of Health
COVID-19 HOSPITALIZATIONS & DEATHS BY AGE
6,000
                                                                                                   5,407
               Cumulative numbers in Arkansas,
5,000                                                                                                                                          4,651
               as of April 12, 2021
4,000
                                                                                                                         3,911
                                                                                                                                                        3,371
3,000
                                                                             2,375
2,000
                                                                                                                                   1,267
                                                                                                             930
1,000
                                   302                   477
             164                             2                     6                   131
     0
                  0-5                  6-18                 19-24                 25-44                 45-64                 65-74                  75+
                                                                          Age Group
          Hospitalizations                       Deaths

Source: ACHI Analyses of Arkansas Department of Health data. | All death data are provisional and subject to change based on further review by the Arkansas
Department of Health.
NEW REPORTED COVID-19 DEATHS IN AR PER DAY
30
                                                                                                              28
                                                                                                                   27
               26
                                                                                                         25
25                                                                                             24
                                                                                          22

20                                                                                                                           19
                                                                                                                        18

                                                                                                                                                                                                    15
15                                         14                                        14             14                                     14       14
                         13                                                                                                                                              13
          12                  12                                           12                                                         12                                           12
                                                                                                                                                                              11
     10             10                          10101010                        10                                                                                                                       1010
10                                 9
                                                                                                                                                8                                                                                                       8
                                                               7       7                                                          7                                                     7                                        7                          7
                                       6                                                                                                                     6                                  6
                                                                                                                                                                 5                          5                              5 5
5                                                                  4                                                                                     4                                                                                          4
                                                                                                                                                                     3                                          3
                                                                                                                                                                                                                    2 2              2
                                                                                                                                                                                                                                              0 0
0
     2/15                              2/23                *           3/3                                3/11                                  3/19                                3/27                             4/4                        4/12
                                                                                                                                                                                                                                         -1

-5

     * On Feb. 28, the Arkansas Department of Health conducted a data clean-up resulting in 174 deaths being removed due to reclassification or duplication.
     Source: Arkansas Department of Health
COVID-19 LONG-TERM EFFECTS: STUDIES
o JAMA study of recovered patients: 78% with structural heart
  damage, 60% had myocarditis*

o JAMA Big Ten Study: 15% of COVID-positive athletes had
  signs of myocarditis, another 30% had inconclusive evidence
  of strain**

o The Lancet: 6 months after COVID-19 infection, 34% of
  patients had new neurologic or psychiatric diagnosis and 13%
  had first-time neurologic or psychiatric diagnosis***

* Puntmann VO, et al. Outcomes of Cardiovascular Magnetic Resonance Imaging in Patients Recently Recovered From Coronavirus Disease 2019 (COVID-19). JAMA Cardiol. July 27, 2020
** Rajpal S, Tong MS, Borchers J, et al. Cardiovascular Magnetic Resonance Findings in Competitive Athletes Recovering From COVID-19 Infection. JAMA Cardiol. Published online Sept. 11, 2020
*** Taquet M., et al. 6-month Neurological and Psychiatric Outcomes in 236,379 Survivors of COVID-19. The Lancet Psychiatry. doi: https://doi.org/10.1101/2021.01.16.21249950. April 6, 2021.
CORONAVIRUS VARIANTS
o Variants of concern and where they first emerged:
       o      B.1.1.7 – U.K.
       o      B.1.351 – South Africa
       o      P.1 – Brazil / B.1.1.248 – Japan (nearly identical)
       o      B.1.427/B.1.429 – U.S. (California)
       o      B.1.526 – U.S. (New York)

o Study of B.1.1.7 variant: more infectious, suggests higher
  death rate*
       o Now most common strain in U.S., CDC chief said last week**

Sources: CDC, Arkansas Department of Health
* BMJ 2021;372:n579 (R. Challen, et al. Risk of mortality in patients infected with SARS-CoV-2 variant of concern 202012/1: matched cohort study); Published March 10, 2021.
** CDC says variant from the UK is now the most common strain circulating in the U.S. https://www.cnbc.com/2021/04/07/cdc-says-variant-from-the-uk-is-now-the-most-common-strain-circulating-in-the-us.html
TRACKING THE SPREAD OF VARIANTS IN THE U.S.

                                                                                                                        1 Variant of Concern:
                                                                                                                        B.1.1.7 (discovered, U.K.)

                                                                                                                        2 Variants of Concern:
                                                                                                                        B.1.1.7
                                                                                                                        P.1 (discovered, Brazil)

                                                                                                                        2 Variants of Concern:
                                                                                                                        B.1.1.7
                                                                                                                        B.1.351 (discovered, S. Africa)
                                                                                                                        3 Variants of Concern:
                                                                                                                        B.1.1.7
                                                                                                                        P.1
                                                                                                                        B.1.351

Source: NBCNews.com. Map: Track the spread of the Covid-19 variants across the United States, updated April 12, 2021.
NEW YORK TIMES VACCINE TRACKER
                  Updated April 15, 2021

                     Pfizer asked the FDA on April 9 to authorize
                           its vaccine for children ages 12–15

Source: Coronavirus Vaccine Tracker, New York Times: nytimes.com/interactive/2020/science/coronavirus-vaccine-tracker.html
COVID-19 VACCINATION PROGRESS IN ARKANSAS
         All Arkansans 16 or older are eligible for the COVID-19 vaccine

Source: Arkansas Department of Health, as of April 14.
COVID-19 VACCINATION PROGRESS IN ARKANSAS

Source: Arkansas Department of Health, as of April 14.
VACCINES AGAINST 3 VARIANTS OF CONCERN
  o B.1.1.7 (U.K.): Pfizer, Moderna remain highly effective
  o P.1 (Brazil): Pfizer, Moderna are 4–7 times less effective
         o Appear to be within an important "cushion of protection," particularly
           after 2 doses

  o B.1.351 (South Africa): Pfizer, Moderna 6–8 times less effective
         o AstraZeneca vaccine was 86 times less effective against B.1.351
         o J&J also less effective during clinical trials in South Africa

  o J&J, Moderna, Pfizer exploring options to improve effectiveness
    against variants (additional doses, reformulations, etc.)
Source: Where Do COVID Vaccines Stand Against the Variants? March 30, 2021. webmd.com/vaccines/covid-19-vaccine/news/20210330/where-do-covid-vaccines-stand-against-the-variants
COVID-19 VACCINES AND BLOOD CLOTS
o Johnson & Johnson vaccine rollout on pause in U.S. while
  FDA investigates blood clots in 6 recipients (out of 6.8M)
       o Cases extremely rare (fewer than 1 per million)
       o All cases were in women between 18 and 48 years of age
       o One death and one hospitalized in critical condition
o AstraZeneca — not approved in U.S. — also on pause or
  restricted in some countries
o J&J and AstraZenica share similar technology that is different
  from Moderna and Pfizer vaccines
       o Blood clots have not been observed with Moderna or Pfizer vaccines

Source: New York Times. https://www.nytimes.com/2021/04/13/us/politics/johnson-johnson-vaccine-blood-clots-fda-cdc.html
CDC GUIDANCE FOR FULLY VACCINATED PEOPLE
o Fully vaccinated defined as:
       o 2 weeks after single-dose vaccine OR the second dose in 2-dose series

o Fully vaccinated individuals can gather:
       o Indoors with other fully vaccinated people w/o masks
       o Indoors with unvaccinated people from 1 other household w/o masks,
         unless they or someone they live with is at high risk

o If exposed to COVID-19:
       o No need to isolate or get tested unless you develop symptoms
       o Except in group living: isolate 14 days & get tested, even w/o symptoms

Source: Centers for Disease Control and Prevention, updated April 2, 2021, https://www.cdc.gov/coronavirus/2019-ncov/vaccines/fully-vaccinated.html
FULLY VACCINATED? WHAT HAS NOT CHANGED
o Wear a mask, stay 6 feet apart, avoid crowds:
       o In public
       o At gatherings with unvaccinated people from more than 1 household
       o When visiting with unvaccinated people at high risk

o Continue to avoid medium- or large-sized gatherings
o Watch for symptoms, especially if around someone sick
       o If you develop symptoms: get tested, stay home

o Continue to follow guidance at your workplace

Source: Centers for Disease Control and Prevention, updated April 2, 2021, https://www.cdc.gov/coronavirus/2019-ncov/vaccines/fully-vaccinated.html
CDC GUIDANCE ON DOMESTIC TRAVEL
o Recommended to delay
  travel unless fully vaccinated
o Fully vaccinated travelers:
       o Don’t need to get tested, unless
         destination requires it
       o Don’t need to self-quarantine
       o Should still wear masks, stay 6
         feet apart, wash hands often

o Self monitor after travel &                                                                                                              Photo by Ashim D’Silva on Unsplash

  follow all local requirements
Source: CDC. Domestic Travel During COVID-19, updated April 2, 2021. https://www.cdc.gov/coronavirus/2019-ncov/travelers/travel-during-covid19.html
ENGINEERING MODEL SHOWING VENTILATION IMPACT

                                                                                                      INFECTED
                                                                                                      STUDENT

Source: Why Opening Windows Is a Key to Reopening Schools, The New York Times, Feb. 26, 2021. nytimes.com/interactive/2021/02/26/science/reopen-schools-safety-ventilation.html
SCENARIO 1: CLASSROOM WINDOWS CLOSED

                                                                                                         Dense reddish fog shows high
                       INFECTED STUDENT                                                                  concentration of contaminants
                                                                                                         spreading far beyond 6 feet
                                                                                                         from the infected student. The
                                                                                                         pattern would be different, but
                                                                                                         the buildup similar, no matter
                                                                                                         where the student was seated.

Source: Why Opening Windows Is a Key to Reopening Schools, The New York Times, Feb. 26, 2021. nytimes.com/interactive/2021/02/26/science/reopen-schools-safety-ventilation.html
SCENARIO 2: WINDOW OPEN

                  WINDOW OPEN

                                                                                                         With the window open, the
                       INFECTED STUDENT
                                                                                                         concentration remains densest
                                                                                                         near the infected student, but
                                                                                                         contaminants are diluted in the
                                                                                                         rest of the room. Exposure for
                                                                                                         other students is reduced.

Source: Why Opening Windows Is a Key to Reopening Schools, The New York Times, Feb. 26, 2021. nytimes.com/interactive/2021/02/26/science/reopen-schools-safety-ventilation.html
SCENARIO 3: FAN BLOWING & AIR CLEANER
               FAN

                                                                                                         With an air cleaner and a fan,
                       INFECTED STUDENT
                                                                                                         overall concentration levels are
                                                                                                         at their lowest. Contaminants
                                                                                                         are concentrated at the front
                                                                                                         where the fan is blowing and
                                                                                                         diluted everywhere else.
                                                  AIR CLEANER

Source: Why Opening Windows Is a Key to Reopening Schools, The New York Times, Feb. 26, 2021. nytimes.com/interactive/2021/02/26/science/reopen-schools-safety-ventilation.html
2021 COVID-19 STRATEGY
                  Action

      Science              Logic
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@ACHI_net                            @JoeThompsonMD

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