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CLUSTER 1 – Health WP 2021-2022 Unlocking the full potential of new tools, technologies and digital solutions for a healthy society; Maintaining an innovative, sustainable & globally competitive health industry Nir Shaked, Head of Sector & National Contact Point Nir.s@iserd.org.il
Disclaimer
The participation of Israeli entities, as associated country, in Horizon Europe projects, is
subject to the signing of the 'Association Agreement' to the programme between Israel and
the EU, before the first project's Grant Agreement (GA) is signed.
The presentation of draft topics and the feedback provided shall in under no circumstances
bind the European Commission in the final formulation of topics for the call.
The binding call text will be published following the formal decision by the European
Commission on the Funding and tender opportunities portal
Participating Countries
27 Member States (MS) 17 Associated Countries (AC)
Austria (AT) France (FR) Malta (MT) Albania (AL) Montenegro (ME)
Belgium (BE) Germany (DE) Netherlands (NL) Armenia (AM) Norway (NO)
Bulgaria (BG) Greece (GR/EL) Poland (PL) Bosnia and Serbia (RS)
Herzegovina (BA)
Croatia (HR) Hungary (HU) Portugal (PT) Faroe Islands (FO) Switzerland (CH)
Cyprus (CY) Ireland (IE) Romania (RO) Georgia (GE) Tunisia (TN)
Czech Republic Italy (IT) Slovakia (SK) Iceland (IS) Turkey (TR)
(CZ)
Denmark (DK) Latvia (LV) Slovenia (SI) Israel (IL) United Kingdom
(UK)
Estonia (EE) Lithuania (LT) Spain (ES) Macedonia (MK) Ukraine (UA)
Finland (FI) Luxembourg Sweden (SE) Moldova (MD)
(LU)
Main Types of Action
Action Funding* Main Characteristics
RIA – Research & 100% + Basic and applied research, technology development and
Innovation Action 25% integration, testing, demonstration and validation on small-scale
prototype in laboratory or simulated environment
IA – Innovation 70% + 25% Prototyping, testing, demonstrating, piloting, large-scale product
Action validation and market replication
CSA - Coordination 100% + Networking, coordination or support services, policy dialogues
& Support Action 25% and mutual learning exercises and studies
* Non profit – always 100%
Horizon Europe (2021-2027)
53.5
25 B€ B€ 13.6 B€
8.2
2.3
16 B€ 10.1 B€
1.6
15.3
15.1
0.5 B€
6.6 B€ 9
2.4 B€ 2 3 B€
2.9 B€ 0.4 B€
Budget of € 95.5 billion for Horizon Europe
Terminology
Horizon Europe Framework Programme
o Pillar
˗ Cluster
▪ Destination
› Call
• Topic
Cluster Health Aims: To contribute to the promotion of social cohesion and inclusiveness and the health and well being of people. To help develop “ an economy that works for people ” by supporting research (and coordination) in order to make innovative, high quality health technologies and health care both available and affordable for citizens To make health care systems more accessible and sustainable , including through the digital transformation of health and care.
Health Cluster – Six Destinations 1. Staying healthy in a rapidly changing society 2. Living and working in a health promoting environment 3. Tackling diseases & reducing disease burden 4. Ensuring access to innovative, sustainable & high quality Healthcare 5. Unlocking the full potential of new tools, technologies and digital solutions for a healthy society 6. Maintaining an innovative, sustainable & globally competitive health industry
Health Cluster – Six Destinations 1. Staying healthy in a rapidly changing society 2. Living and working in a health promoting environment 3. Tackling diseases & reducing disease burden 4. Ensuring access to innovative, sustainable & high quality Healthcare 5. Unlocking the full potential of new tools, technologies and digital solutions for a healthy society 6. Maintaining an innovative, sustainable & globally competitive health industry
Destination 5 - Unlocking the full potential of new tools, technologies and digital solutions for a healthy society ~ € 270M Expected impacts • Contribute to Europe’s scientific and technological expertise and know how, its capabilities for innovation in new tools, technologies and digital solutions, and its ability to take up, scale up and integrate innovation in health and care; • Enable researchers, innovators and health care providers to use health data and AI supported decision making in a secure and ethical, acceptable and trustworthy manner. • Citizens should benefit from targeted and faster research resulting in safer, more efficient, cost effective and affordable tools, technologies and digital solutions for effective personalised disease prevention, diagnosis, treatment and monitoring for better patient outcome and well being, in particular through increasingly shared health resources.
Destination 5 - Unlocking the full potential of new tools, technologies and digital solutions for a healthy society ~ € 270M Call – Tools and technologies for a healthy society (21/09/2021) Call – Tools and technologies for a healthy society (Two Stage – 01/02/2022; 06/09/2022) Call – Tools and technologies for a healthy society (Single Stage – 21/04/2022)
HORIZON-HLTH-2021-TOOL-06-01: Smart medical devices and their surgical implantation for use in resource- constrained settings – IA € 6M x 4 TRL4-7 Expected outcomes: Medical device developers provide sustainable and affordable smart active implants validated in the operational environment. Medical professionals in resource-constrained clinical settings use sustainable and affordable surgical procedures for smart active implants. Patients have access to sustainable and affordable smart medical devices suitable for minimally invasive surgical implantation through further clinical studies.
HORIZON-HLTH-2021-TOOL-06-01: Smart medical devices and their surgical implantation for use in resource-constrained settings – IA € 6M x 4 TRL4-7 Scope: Develop “smart” (micro-electronic sensor/actuator) surgically-implanted active medical device to achieve any desired physiological response (e.g. orthopaedic, neural, cardiovascular, metabolic, etc.), Necessitate appropriate tailored surgical implantation procedures and interventions compatible with resource-constrained environments. Address challenges such as miniaturization, sensor robustness, wireless power supply, etc. Medical device design, regulatory work, clinical stages and developmental iterations, TRL 4-7, involve surgeons and/or other health care professionals, developers, patients and relevant regulatory bodies. Consider meeting all the requirements of the new EU legal framework on medical devices.
HORIZON-HLTH-2021-TOOL-06-02: Next generation advanced therapies to treat highly prevalent and high burden diseases with unmet medical needs – RIA € 6M x 10 Expected outcomes: Authorities, researchers and developers use assessments of efficiency, delivery, safety, and/or potency of novel therapeutic interventions based on either pluripotent stem cells, genome editing or RNA, aligned with standards. Clinicians, researchers and developers test new therapies based on pluripotent stem cells, gene editing or RNA ready through clinical trials meeting the regulatory requirements.
HORIZON-HLTH-2021-TOOL-06-02: Next generation advanced therapies to treat highly prevalent and high burden diseases with unmet medical needs – RIA € 6M x 10 Scope - address one or several of the following: Develop method for production and differentiation of pluripotent stem cells (defined as cells that can give rise to cells from all three embryonic germ layers). Complementary activities to assess safety, in vivo validation or upscaling procedures could be considered. Develop and validate methods that can demonstrate efficacy, delivery, specificity, and safety of genome editing products in targeted cells and tissues (e.g. base editing, prime editing, transcription activator-like effector nucleases, zinc-finger nucleases, clustered regularly interspaced short palindromic repeats). Complementary activities to assess in vivo validation or upscaling procedures could be considered. Develop and validate novel RNA-based therapeutics targeting noncommunicable diseases. Complementary activities to assess mode of action, delivery, safety, in vivo validation and/or upscaling procedures could be considered. Study, analyse and tackle different immune responses, generated by any of the above-mentioned advanced therapies in vivo, facilitating regulatory approval for next phase of research and development.
HORIZON-HLTH-2021-TOOL-06-03: Innovative tools for use and re-use of health data (in particular of electronic health records and/or patient registries) – RIA € 8M x 4 Expected outcomes: Novel solutions improve quality, ensure interoperability and enable re-use of health data, data analytics and metadata from different repositories and/or countries, by health professionals, researchers and health authorities, in compliance with FAIR data management principles as well as national and EU legal and ethical requirements. Professionals & authorities use tools enabling them to exploit unstructured and heterogeneous data. Increased use and valorisation of health data by patients, researchers and clinicians thanks to better data portability due to the standardization of meta data and clinical data, from different clinical services, sites & countries. Professionals use efficient cost-effective health care procedures and workflows that contributing to disease prevention, early detection/diagnosis and effective treatment.
HORIZON-HLTH-2021-TOOL-06-03: Innovative tools for use and re-use of health data (in particular of electronic health records and/or patient registries) – RIA € 8M x 4 Scope: Develop solutions to improve the quality, interoperability, machine-readability and re-use of health data and metadata in compliance with legal requirements & FAIR data management principles, making it accessible to clinicians, researchers and citizens. Focus on electronic health records (EHRs) and/or patient registries, consider the European Electronic Health Record exchange format. Develop natural language processing tools, including computational semantics, ontologies, text mining, associated machine learning and deep learning, to improve accessibility, interoperability, translation, transcription, and analysis of health data (e.g. to predict risks). Tools should extract health information from unstructured data in different clinical and medical sources, and bring that data into EHRs/patient registries in a structured form. Develop and pilot AI-powered virtual assistants that will utilise the tools and solutions developed, to demonstrate improved usability of health data for end-users.
Destination 5 - Unlocking the full potential of new tools, technologies and digital solutions for a healthy society ~ € 270M Call – Tools and technologies for a healthy society (21/09/2021) Call – Tools and technologies for a healthy society (Two Stage – 01/02/2022; 06/09/2022) Call – Tools and technologies for a healthy society (Single Stage – 21/04/2022)
HORIZON-HLTH-2022-TOOL-12-01-two-stage: Computational models for new patient stratification strategies – RIA € 6M x 10 Expected outcomes: Clinical researchers use effective health data integration solutions for the classification of the clinical phenotypes. Professionals use robust and validated data- driven computational tools to successfully stratify patients. Regulatory bodies approve computer-aided patient stratification strategies to enable personalised diagnosis and/or therapy strategies. Professionals adopt evidence-based guidelines for stratification-based patient management superior to the standard-of-care.
HORIZON-HLTH-2022-TOOL-12-01-two-stage: Computational models for new patient stratification strategies – RIA € 6M x 10 Scope – address one or several of the following areas: Establish interdisciplinary research by bridging disciplines and technologies (disease biology, clinical research, data science, -omics, computational and mathematical modelling of diseases, advanced statistical and/or AI/machine learning methods, Virtual Physiological Human and/or digital twin technologies). Develop new computational models for the integration of complex health data from multiples sources, including structured and unstructured data. Develop and optimise robust, transparent and accurate computational models to guide patient stratification strategies for improving clinical outcomes. Demonstrate, test and clinically validate such models with respect to their utility to realistically stratify patients with the aim of improving the standard-of-care. Develop new patient stratification strategies guided by computational models and validate it in pre-clinical and/or clinical studies.
Destination 6 - Maintaining an innovative, sustainable & globally competitive health industry ~ € 113M Expected impacts • A Health industry should be more competitive, sustainable and growing, providing high value jobs and contributing to economic growth, in particular SMEs, by tapping into new markets and providing European leadership in health technologies and innovations. • Citizens, health care providers and health systems should benefit from swift uptake of innovative health technologies and services offering significant improvements. • Health industry should work more efficiently along the value chain from the identification of needs to the scale up and take up of solutions at national, regional or local level, including through early engagement with all stakeholders to ensure suitability and acceptance of solutions.
Destination 6 - Maintaining an innovative, sustainable & globally competitive health industry ~ € 113M Call – Tools and technologies for a healthy society (21/09/2021) Call – Tools and technologies for a healthy society (Single Stage – 21/04/2022)
HORIZON-HLTH-2021-IND-07-01: Green pharmaceuticals – RIA € 8M x 5 Expected outcomes: Researchers and regulators understand the environmental impact of pharmaceuticals. Public authorities polices based on scientific evidences. Researchers, innovators and pharmaceutical industries develop and produce greener pharmaceuticals that are either greener by design, intrinsically less harmful for the environment, and/or use greener and economically more sustainable manufacturing processes.
HORIZON-HLTH-2021-IND-07-01: Green pharmaceuticals – RIA € 8M x 5 Scope – Address several of the following: R&I to support the development of “greener” pharmaceuticals that degrade more readily to harmless substances in wastewater treatment plants and the environment; Research on the eco-toxicity and environmental fate of pharmaceuticals; Propose innovative manufacturing technology that is greener, low in energy consumption and emissions, using less solvent or recycling solvents; Propose methods for eliminating carcinogenic impurities in pharmaceuticals (e.g. nitrosamines) process and medicinal products, in particular as complementary technologies to the manufacturing methods relying on recycled solvents; Explore innovative uses of digital transformation or robotic for competitive and scalable methods of production.
HORIZON-HLTH-2021-IND-07-02: Development, procurement and responsible management of new antimicrobials – CSA € 2M x 1 Scope: Emerging health threats, particularly those resulting from antimicrobial resistance (AMR), and identification of relevant public health needs in the development of new antibiotics. Design a pull incentive that combines EU support for late stage development of antimicrobials with procurement by Member States and Associated Countries (implementation of the pull incentive will be beyond the scope of this CSA). Readiness and interest of potential developers/suppliers of antimicrobials. Market failures and the challenges of availability and accessibility of therapeutics. Conditions for development and purchase of new antimicrobials. Requirements for financing. Conditions for prudent use of new antimicrobials.
HORIZON-HLTH-2021-IND-07-03: Promoting a trusted mHealth label in Europe: uptake of technical specifications for quality and reliability of health and wellness apps – CSA € 2M x 1 Scope: Set up a structured dialogue on the uptake of the technical specifications between app developers, health care system representatives, app stores, medical societies, patient organisations, users (including health care professionals) and certification bodies, building a digital ecosystem around a trustable mHealth label. Co-create, develop and implement an action plan on the promotion of the mHealth label in the health care system. Implement concrete actions on the integration and use of secure and qualitative health and wellness apps, using the new label, in specific health care settings, covering the entire EU. Ensure that the promoted health and wellness apps are bias-free and adequately address the needs of different social groups, considering gender, age, ability and ethnicity, where relevant. Support and set-up an inclusive dissemination strategy to promote the use of the mHealth app quality label (cfr. EU energy labels and EU Nutri-Score nutrition label) taking into account the different levels of digital health literacy among the actors involved. Interests of different age groups, sex & gender, LGBT+, disabled, ethnic, etc.
Finding Partners 1. Use your network 2. Take part in future brokerage events 3. Search previously funded projects 4. Use us – Send us a one-pager
Prepare a topic-specific one-pager
1. Use an official logo paper, pay attention to graphics as well as content
2. Start with a title that explains exactly what you want so that target crowed will actually read it : An
Israeli SME/Researcher/NGO … that specializes in…. is looking for an
opportunity to join a consortium preparing a proposal under call topic XYZ…
3. If you have already participated in an EU funded project, mention it immediately after the title –
experience makes you very attractive!
4. The first paragraph should explain EXACTLY how is your expertise relevant to the chosen call topic.
o If you have more then one in mind, prepper several different one-pagers.
o This is the most interesting paragraph.
o No potential partner will guess or think for you how you can fit.
5. Only then write about yourself, your expertise and your achievements. This is interesting only if
someone found the beginning of this one-pager interesting enough to keep on reading…
6. Lastly Your Full contact details.
7. Save as PDF and upload Here > Cluster 1 One-Pagers DriveHuman Brain Project & EBRAINS Call: Impact of Covid-19 on brain and mental health Call for Expression of Interest (CEol) The deadline to submit proposals is 30 April 2021 at 17:00 Two proposals will be selected according to specific criteria outlined the call documents Maximum funding per proposal is EUR 225,000 (plus 25% Indirect Costs) ISERD contact point: Tzlil.Ribak@iserd.org.il HBP contact Point: info@opencalls.humanbrainproject.eu Further information, Documents and Deadlines: https://opencalls2.humanbrainproject.eu/call/hbp-sga3-ceoi-covid-19
www.iserd.org.il
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