RESEARCH WEEK 20 - 24 AUGUST 2018 - St John of God Health Care
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RESEARCH WEEK 20 – 24 AUGUST 2018 Hospitality | Compassion | Respect | Justice | Excellence
Welcome Welcome to the St John of God Health Care Research Week. This week highlights the research undertaken at St John of God Subiaco and Murdoch hospitals and other local research institutes, and offers an opportunity to further develop the skills of our researchers. Hospital research is critical to ensuring our clinical care is underpinned by the best evidence available to improve patient outcomes and develop new levels of clinical excellence. Research is undertaken across a variety of areas, including nursing, midwifery, medical and allied health practices, respiratory, orthopaedics, oncology, cardiology, emergency medicine, intensive care and pain treatment. Much of our research is undertaken collaboratively with clinical, university and donor partners and we continue to seek new opportunities in other disciplines and clinical areas. With Research Week events held at both hospitals, we are pleased to present a number of special guests including Dr Christina Davies from the School of Population and Global Health UWA, Professor Selma Alliex from University of Notre Dame (Fremantle) alongside our own Research Lead Investigators Professor Tom Corcoran, Professor Steve Webb, Professor Eric Visser and Dr Paul Cohen. sjog.org.au/researchweek T: 08 6465 9364 | E: research.network@sjog.org.au 2 3
Monday 20 August 2018 Monday 20 August 2018
Nursing & Midwifery Research Symposium
Time: 8.30am – 4.05pm
Location: St John of God Murdoch Hospital Auditorium, MURTEC Entrance
Presenters: Professor Selma Alliex, Ms Cynthia Dowell
Presentations will be streamed live to St John of God Subiaco Hospital Conference
Centre Auditorium.
8.30AM Registration
9.00AM Presentations
4.05PM Sundowner
Professor Selma Alliex
The Perfect Fit: Research and Caring
Professor Selma Alliex is the Pro Vice-Chancellor and Head of Fremantle
Campus, University of Notre Dame Australia. Professor Selma Alliex was
formerly Dean of the School of Nursing at the Fremantle and Broome
campuses and taught in the undergraduate and postgraduate program
in the School. She has nursing education experience in Australia and
overseas and continues to supervise higher degree students. Her area of
expertise is nursing education and qualitative research. As part of her
administrative role, Professor Alliex in association with other academics
is trialing many innovations in nursing education. Prior to teaching at
the University, Professor Alliex was the Nursing Adviser for Professional
Standards at the Nurses Board of Western Australia Symposium speakers
The symposium will include oral and poster presentations from nurses, midwives and allied health
caregivers from St John of God Murdoch and Subiaco Hospitals.
Ms Cynthia Dowell Research projects initiated by nursing, midwifery and allied health caregivers will be featured.
St John of God Health Care Presentations for this symposium are still being finalised and further information will be available
Cynthia Dowell is the Group Director of Nursing, St John of God Health on the website in due course.
Care. She commenced the role at the beginning of 2016. Cynthia is
passionate about her role and the role that each of the 6000 plus nurses
at St John of God Health Care’s divisions play in delivering contemporary
patient focused nursing care. She has more than 20 years’ experience in
health care including nursing and executive leadership roles. Cynthia’s WAHTN Clinical Trials Forum
previous roles have included Chief Nursing Officer and Executive Director
of Surgery and Specialist services at St Vincent’s Hospital in Melbourne. Time: 4.30pm – 6.00pm
Location: St John of God Murdoch Hospital Auditorium, MURTEC Entrance
Presenters: Dr Paul Cohen and Professor Tom Corcoran
The WA Health Translation Network Clinical Trials Forum is an opportunity to share knowledge,
experience, advice and ideas, in relation to current proposals for clinical trials, with a wide range
of researchers from Western Australia. The forum occurs monthly and involves presentation and
discussion of two clinical trial proposals. Proposals are welcome from both experienced and less
experienced investigators.
4 5
Tuesday 21 August 2018 Tuesday 21 August 2018
Lecture: Platform Trials to Optimise Outcomes in Patients Undergoing TOPIC SPEAKER
Elective Surgery
Time: 7.00am – 8.15am Infrastructure for Perioperative Medicine Research
Location: St John of God Subiaco Hospital, Level 3 Conference Centre
Presenter: Professor Steve Webb Welcome and Introductions Professor Steve Webb
Details: A light breakfast will be served
A History of the ANZCA CTA John Rigg
Professor Steve Webb
Barriers, Enablers, Scope for Peri-operative Medicine Research
Professor Steve Webb is a senior staff specialist in Intensive Care Professor Steve Webb
at St John of God Health Care
Medicine at St John of God Subiaco Hospital and Royal Perth Hospital,
a Professor of Critical Care Research at Monash University, a Clinical
Novel Trial Designs in Anaesthesia Professor Tom Corcoran
Professor at The University of Western Australia and the Director
of Clinical Trials, as well as the Chair of the Research Management
Committee, at St John of God Subiaco Hospital. Randomised Embedded Platform Trials Professor Steve Webb
Professor Webb is a past chair of the Australian and New Zealand
Recruitment into Anaesthesia Trials –
Intensive Care Society Clinical Trials Group, a founding Director and What Works and What Doesn’t
Yvonne Buller
Deputy Chair of the Australian Clinical Trials Alliance, a foundation
Fellow and a member of Council of the Australian Academy of Health
Digital Transformation at St John of God Health Care Lex Julian
and Medical Sciences and a member of the National Health and
Medical Research Council Health Translation Advisory Committee.
He has published more than 150 journal articles, including manuscripts Automated Measurements of Patient Reported Outcome Measures
Chris Reid
and Data Linkage
in the New England Journal of Medicine, Journal of the American
Medical Association, Lancet and BMJ. He is a recipient of more than
$85 million in grant funding and has conducted multiple clinical trials Standardised Outcome Measures in Peri-operative Medicine Research Professor Tom Corcoran
that provided definitive guidance on optimal management for patients
with various forms of critical illness. Morning Tea
Research Priorities in Perioperative Medicine Research
Variation in Practice Professor Steve Webb
Workshop: Elective Surgery, Anaesthesia, Perioperative Medicine
Time: 9.00am – 12.00pm Enhanced Recovery After Surgery (ERAS) Dr Paul Cohen
Location: St John of God Subiaco Hospital, Level 3 Conference Centre
Presenters: Professor Steve Webb, John Rigg, Professor Tomas Corcoran, Yvonne Buller, Cancer Recurrence After Resection Cameron Platell
Lex Julian, Chris Reid, Dr Paul Cohen, Cameron Platell, Ed O’Loughlin,
Christobel Saunders What Questions Need to be Answered in Anaesthesia Professor Tom Corcoran
Workshop on research methods to improve outcomes for patients having elective surgery.
Pre-operative Optimisation Professor Steve Webb
What Do Patients Want from Elective Surgery? Christobel Saunders
Discussion and Next Steps
6 7
Tuesday 21 August 2018 Tuesday 21 August 2018
Lecture: Future Anaesthesia Trials at SJG: New Trial Designs Professor Eric Visser
and Implications for Care Research Update: Antioxidants
Time: 12.00pm – 1.00pm and the Management of Migraine
Location: St John of God Subiaco Hospital, Level 3 Conference Centre Professor Eric Visser is a specialist pain medicine physician and
Presenter: Professor Tom Corcoran anaesthesiologist at St John of God Subiaco Hospital and Joondalup
Details: Refreshments served after lecture Health Campus. He has wide-ranging interests, including pain
education, acute pain service applications, spinal pain, migraine,
Professor Tom Corcoran pharmacological pain management and peripheral neural blockade
for chronic pain.
Professor Tom Corcoran is the Director of Research in Anaesthesia and
Pain Medicine in Royal Perth Hospital, Clinical Professor in the University In 2015 the University of Notre Dame Australia (Fremantle) and St
of Western Australia, an inaugural Raine Foundation Clinical Research John of God Subiaco Hospital appointed Professor Eric Visser as the
Fellow, and Adjunct Clinical Professor at the School of Public Health inaugural Churack Chair of Chronic Pain Education and Research in
and Preventive Medicine, Monash University. He is also a member of the the School of Medicine. As the Chair, Professor Visser is tasked with
Executive Committee of the ANZCA Clinical Trials Network. reducing the impact of chronic pain, one of the biggest unrecognised
health problems in the community, through furthering research and the
Professor Corcoran is a chief investigator on two NHMRC-funded trials
education of medical students in the area of chronic pain management.
(BALANCED and RELIEF), and in 2014 he was awarded the largest project
grant from the NHMRC for the PADDI Trial, receiving $4.6 million to
determine the relationship between perioperative dexamethasone
administration and surgical site infection. He has an active interest Dr Derek Eng
in perioperative genomics, chronic post procedural pain, perioperative
medicine and patient outcomes research. Getting Advance Care Planning Right – Research
Results Drive Clinical Change in WA Hospitals
Dr. Derek Eng is a Palliative Medicine Physician in Perth, Western
Australia. He is presently the Head of Palliative Care Services at
GP CPD Education: Pain and Palliative Care Medicine St John of God Subiaco Hospital and Palliative Medicine Physician
Time: 6.30pm – 9.00pm at Royal Perth Hospital.
Location: St John of God Subiaco Hospital, Level 3 Conference Centre Auditorium Dr. Eng is a Senior Lecturer in Palliative Medicine at the University of
Presenters: Ms Jill Kelly, Professor Eric Visser, Dr Derek Eng Western Australia and Notre Dame University, Fremantle. He is Lead
Clinician at the Department of Health WA for communication skills
teaching and has been training educators/facilitators and health
6.30PM Registration professionals in clinical communication in healthcare.
Dr Eng has been heavily involved in research and implementation of
7.00PM Education the Goals of Patient Care project throughout WA Health.
Ms Jill Kelly
One for the Road: Opioid Prescribing for Discharge
Acute Pain Service Nurse Practitioner Jill Kelly was the first nurse
practitioner appointed in a private hospital in Australia and the first Nurse
Practitioner working in a pain management context in Western Australia.
Ms Kelly is Adjunct Senior Lecturer at the University of Notre Dame’s
(Fremantle) School of Medicine, co-facilitating the development of
pain management education programs to be made available to health
professionals throughout Western Australia.
She is a lead investigator in a study investigating the post-discharge patient
experience of 300 surgical day cases from a pain perspective. This study is
in partnership with Professor Eric Visser and The Churack Chair of Chronic
Pain Education and Research at the University of Notre Dame (Fremantle).
8 9
Wednesday 22 August 2018 Wednesday 22 August 2018
Art in Health: Arts and Health Research at St John of God Health Care
Time: 11.15am – 12.30pm
Location: St John of God Subiaco Hospital, Level 3 Conference Centre Auditorium
Presenter: Dr Christina Davies, Ms Deborah Pearson
Since 2014, St John of God Health Care (SJGHC) has been committed to contributing to the
significant international field of arts and health research This presentation will provide an
overview of arts and health, and arts and health research at SJGHC with specific attention
to the participative arts programs established for patients to support wellbeing, recovery
and pain reduction.
11.15AM Registrations
11.30AM Presentation
12.30PM Light Refreshments
Ms Deborah Pearson
Group Coordinator Arts and Health, St John of God Health Care
and Chairperson WA Arts and Health Consortium
As Group Coordinator Arts and Health, Deborah leads the development
and implementation of the philosophy and framework for Arts and
Health practice across St John of God Health Care. In collaboration
with the Chamber for Arts and Culture WA, she developed the Arts
and Health Seminar Undiscovered Opportunities: Arts in the Healing
Environment (July 2014) out of which grew the WA Arts and Health
Consortium. Deborah was the project lead on the Consortium’s first
project – an Examination of the use of the Arts to improve health
and healing in Western Australian Hospitals (July 2016). Deborah is
currently the project lead for the Consortiums Arts on Prescription
action research project in collaboration with the WA Primary Health
Alliance (WAPHA). Arts on Prescription is a social prescribing approach Dr Christina Davies
that brings together health and arts practitioners as active collaborators School of Population & Global Health, The University of Western Australia.
in improving individual wellbeing and the health in our communities. Adjunct Research Fellow, Public Health Advocacy Institute of WA,
Prior to this, Deborah was SJGHC’s Group Manager Leadership Curtin University
Development (2003–2013) and initiated the beginnings of an arts Dr Christina Davies is a Research Fellow at the School of Population
strategy for SJGHC. and Global Health, The University of Western Australia, and Adjunct
Research Fellow at the Public Health Advocacy Institute of WA,
Curtin. Her multi-award winning research focuses on the area of
arts and health. Translating research into practice, Christina has
been collaborating with St John of God Health Care to implement
and evaluate the impact of hospital-based arts programs for seniors
that support recovery, mental wellbeing and foster artistic interests.
10 11Wednesday 22 August 2018 Wednesday 22 August 2018
Colorectal Cancer Research Symposium: An Overview of Current Dr Chidozie Anyaegbu
Laboratory-based Colorectal Research at St John of God Subiaco Hospital Illuminating Immune Cell Subsets
Time: 12.30pm – 2.30pm in Colorectal Tissue
Location: St John of God Subiaco Hospital, Level 3 Conference Centre Auditorium Dr Chidozie Anyaegbu is a research officer within the Colorectal
Presenters: Dr Melanie McCoy, Ms Tracey Lee-Pullen, Dr Chidozie Anyaegbu, Cancer Research Group at St John of God Subiaco Hospital. Since
Dr Timothy Miller joining the group in 2016, he has been instrumental in advancing their
immune biomarker discovery program through the development of a
cutting edge, immunofluorescence staining and imaging technique for
12.30PM Registrations and light refreshments characterising immune cells in colorectal tumour tissues.
Dr Anyaegbu has a BSc (Hons) degree in Molecular Biotechnology from
1.00PM Presentations Curtin University and a PhD in tumour immunology from UWA. He has
over ten years’ experience in investigating immune responses to cancer.
Dr Anyaegbu’s current research focus is on using multi-parametric
Dr Melanie McCoy immunofluorescence and digital imaging to investigate the prognostic
The Immune System and Response to value of the type, function and spatial distribution of dendritic cells
engaging with T cells in colorectal tumours.
Chemoradiotherapy in Rectal Cancer
Dr Melanie McCoy is a Postdoctoral Research Fellow within the Colorectal
Cancer Research Group at St John of God Subiaco Hospital, where she Dr Timothy Miller
leads a team investigating factors influencing patient clinical outcome.
Her primary research focus is on the role of the immune system in Clinical Value of Cancer Stem Cell Markers in
modulating response to chemotherapy and radiotherapy. Colorectal Cancer
Dr McCoy has been in her current role since 2011, following completion Dr Timothy Miller is a research officer within the Colorectal Cancer
of her PhD examining the effects of chemotherapy on the anti-tumour Research Group at St John of God Subiaco Hospital. He has been
immune response in patients with malignant mesothelioma and involved in colorectal cancer research for over six years and recently
non-small cell lung cancer, awarded by UWA. Prior to this she completed his PhD through UWA under the supervision of Dr Melanie
completed her undergraduate studies in Biology with French McCoy and Prof Cameron Platell. His primary research focus is on using
at The University of Manchester, UK. cancer stem cells as biomarkers of treatment response and survival.
In addition to laboratory-based research, Dr McCoy is also an Dr Miller completed his Bachelor of Science with Honours at UWA in
experienced clinical trial coordinator and data manager. 2011 before joining the group as a graduate research assistant. He began
his PhD in 2014 and has published three peer-reviewed articles and
presented his work at local and national conferences during this time.
Ms Tracey Lee-Pullen Dr Miller is currently working on validating the findings of his PhD work.
Characterising the Immune Response Using Flow
Cytometry and Immunofluorescence
Tracey Lee-Pullen is a research officer in the Colorectal Cancer Research
group at St John of God Subiaco Hospital. She joined the group in 2013
and her main area of research has been characterising the immune
system in patients with rectal cancer.
Tracey has extensive laboratory research experience, with specific
expertise in flow cytometry and cell imaging techniques, including
seven years’ experience in a technical instrument core facility at
UWA teaching microscopy and flow cytometry across a broad range
of research areas.
Tracey moved to Perth in 2002 after completing her undergraduate
studies in Biochemistry at the University of Liverpool, UK. She has
been the Australasian Flow Cytometry Group secretary in 2008 and
conference secretary in 2015.
12 13Thursday 23 August 2018 Thursday 23 August 2018
Junior Doctor Research Dr Paul Cohen
Time: 12.30pm – 1.30pm Setting Your Question and Types of Research
Location: St John of God Subiaco Hospital, Level 3 Conference Centre Auditorium Dr Paul Cohen is a Clinician-Researcher with the Western Australia
Presenters: Dr Meabh McNulty, Dr Tim Ball, Dr Alexandra Wilson Gynaecological Cancer Service and leads the Gynaecological Cancer
Research Group at SJG Subiaco Hospital.
Dr Cohen is the Coordinating Principal Investigator of the Western
Australian Gynaecological Oncology Biospecimen Bank, which has stored
Research Education Session: How to Complete a Successful Junior tissue from over 4000 patients. His group conducts translational research
into biomarkers for ovarian cancer recurrence, population-based studies
Doctor Project using Western Australian linked health data, and research into quality
Time: 6.00pm – 8.00pm of life and exercise in cancer survivors.
Location: St John of God Subiaco Hospital, Level 3 Conference Centre Auditorium He is the Principal Investigator for a national multicentre clinical trial
Presenters: Mr Ed Litton, Ms Nisha Sikotra, Dr Paul Cohen, Professor Steve Webb comparing treatments for glandular pre-cancers of the cervix. He has
conducted research in women with hereditary cancer syndromes at high
risk of breast, ovarian and uterine cancers and is an investigator on the
6.00PM Registrations and refreshments TRACEBACK Study, which recently received almost $3million of Federal
Government funding to trace relatives of women diagnosed with ovarian
6.30PM Education
cancer who may themselves be carriers of gene faults that increase their
risk of cancer.
Dr Cohen is a member of the Cancer Genetics eviQ Reference Committee,
Dr Ed Litton which issues national evidence-based guidelines for the management
Why I Do Research of women and men at high risk of developing malignancies due to
hereditary cancer syndromes. He is also a member of the International
Edward Litton (MBChB, FCICM, MSc Clinical Trials, PhD) is a Staff Gynecological Cancer Society Education Committee and the Editorial
Specialist in Intensive Care Medicine and Director of ICU Research Board of the International Journal of Gynecological Cancer.
at Fiona Stanley Hospital in Perth Western Australia, and a Clinical
Research Fellow in the ICU at St John of God Subiaco Hospital. He is a
Senior Lecturer at the University of Western Australia and a member Professor Steve Webb
of the executive committee of the Australia and New Zealand Intensive
Care Society Centre for Outcomes Research Evaluation. Dr Litton is the The Successful Junior Doctor Project
recipient of over $5 million in research support and has published over
See full presenter bio page 6.
60 manuscripts in peer-reviewed journals. His principle areas of research
include sepsis and pneumonia, high risk patients undergoing cardiac
surgery, iron therapy, acute lung injury and sleep in critical illness.
Ms Nisha Sikotra
Junior Doctor Projects at SJG Subiaco
Nisha Sikotra is a Research Nurse with a BSc Hons in Paediatric
Nursing who has worked in the research field for over eight years and
has extensive experience in setting up and co-ordinating research
studies. Nisha has worked as a clinical trials research nurse in the field
of children’s diabetes in the UK before joining St John of God Subiaco
Hospital in 2013 where she has worked within the areas of perinatal and
infant mental health, pain management and oncology research. Since
2017, Nisha has been involved in establishing and co-ordinating the WA
Thoracic Research Group (WATRG) Biospeciman Bank, which involves the
collection of biospecimans from patients with known or suspected lung
malignancies. Nisha also provides support and guidance to junior doctors
in conducting research projects as part of the Junior Doctor Research
Support Program at St John of God Subiaco Hospital.
14 15St John of God Health Care Research Week 20 – 24 August 2018 St John of God Health Care Research Week 20 – 24 August 2018
Full Event Program St John of God Murdoch
MONDAY 20 August 2018
8.30am – 4.05pm Nursing & Midwifery Research Symposium
Professor Selma Alliex, Ms Cynthia Dowell
MURTEC
4.30pm – 6.00pm WAHTN Clinical Trials Forum
Dr Paul Cohen and Professor Tom Corcoran
TUESDAY 21 August 2018
7.00am – 8.15am Lecture
Platform Trials to Optimise Outcomes in Patients Undergoing
Elective Surgery
Professor Steve Webb
9.00am – 12.00pm Workshop
Elective Surgery, Anaesthesia, Perioperative Medicine
Professor Steve Webb, John Rigg, Professor Tom Corcoran,
Yvonne Buller, Lex Julian, Chris Reid, Dr Paul Cohen,
Cameron Platell, Christobel Saunders
12.00pm – 1.00pm Lecture
Future Anaesthesia Trials at SJG: New Trial Designs and
Implications for Care St John of God Subiaco
Professor Tom Corcoran
CAMBRIDGE STREET
ENTRY ENTRY
6.30pm – 9.00pm GP CPD Education: Pain and Palliative Care Medicine
Ms Jill Kelly, Professor Eric Visser, Dr Derek Eng
SUBIACO ENTRY
WEDNESDAY 22 August 2018 CLINIC
STATION STREET
McCOURT STREET
ENTRY
LIFTS
CHAPEL ENTRY
LIFTS
11.15am – 12.30pm Art in Health: Arts and Health Research at SJGHC MAIN
ENTRANCE
LIFTS LIFTS
HOSPITAL
Ms Deborah Pearson, Dr Christina Davies LIFTS RECEPTION
NORTH NO ENTRY
BLOCK
COURTYARD
12.30pm – 2.30pm Colorectal Cancer Research Symposium: An Overview MULTI LEVEL
CARPARK NO ENTRY
of Current Laboratory-based Colorectal Research at SJG
Subiaco Hospital LIFTS
SOUTH
BLOCK
Dr Melanie McCoy, Ms Tracey Lee-Pullen, Dr Chidozie Anyaegbu,
Dr Timothy Miller
LIFTS
THURSDAY 23 August 2018 MAIN
ENTRY
SA
LV
BFCCC
12.30pm – 1.30pm Junior Doctor Research AD
OR
OA
D
Dr Meabh McNulty, Dr Tim Ball, Dr Alexandra Wilson
6.00pm – 8.00pm Research Education Session: How to complete a Successful
Junior Doctor Project Rest Rooms Information Cafe Accessible Parking Main
Parking Walkway
Dr Ed Litton, Dr Paul Cohen, Professor Steve Webb, Ms Nisha Sikotra
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