WEBINARS A series of live, interactive 2021/22 - PVRI - Pulmonary Vascular ...
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SUP PORTED BY
PVRI
Pulmonary Vascular
Research Institute
WEBINARS
The research continues.
A series of live, interactive
2021/22
Please join us for these exciting new online meetings.
PROGRAMME
PVRI
Pulmonary Vascular
Research Institute
“I am pleased to announce a series of
webinars and online meetings that continue
the fantastic work of the PVRI for our
global members and young scientists.”
Werner Seeger In the absence of the PVRI in-person meetings and symposia, these online
President 2020-2022, webinars will enable us to stay in contact with our worldwide community,
Justus-Liebig University Giessen, but also to explore and discuss important new research.
Germany
Following the success of the DDS 2020 DIGITAL online Drug & Development
Symposium in June 2020, we are excited to launch this series of interactive
live webinars and look forward to active discussion and debate throughout
the year.
During the live webinar sessions, there will be plenty of time set aside for Q&A to encourage active
participation from our audience. All presentations will be available to download after the event.
We encourage you to participate in this exciting new feature and register online.
ReGISTRATIon IS FRee FoR PVRI PAID membeRS.
PVRI
Pulmonary Vascular
Research Institute
Introducing the
Scientific organisers...
We would like to thank our Scientific organising Committee,
Our Scientific Leaders...
under the leadership of Patricia Thistlethwaite and Stephan Rosenkranz,
for putting together such an outstanding programme of stimulating
and novel talks.
Many thanks also to all chairs, speakers and abstract presenters for contributing to
this exciting new feature.
Patricia Thistlethwaite Stephen Rosenkranz
• University of California, • University of Cologne, Details of the abstract submission process and how to register for the webinars
San Diego, USA Germany will soon be available.
Our Scientific Planning Committee...
Sébastien bonnet Allan Lawrie Stelios orfanos Rogerio Souza Rebecca Vanderpool
• Laval University, • University of Sheffield, • University of Athens • University of Sao Paulo, • University of Arizona
Canada UK Medical School, Brazil College of Medicine
Greece - Tuscon, USA
PVRI
Pulmonary Vascular
Research Institute
Webinars
Dates and topics for the webinar series in 2021:
coming up in
Wednesday Wednesday Wednesday Wednesday
27 January 24 February 24 march 28 April
2021 2021 2021 2021
2021
Around the globe: Keynote lecture Connection Virtual poster
Global burden session between discussion
of pulmonary CoVID-19 and session 1
hypertension pulmonary
vascular disease
SAVe The DATeS Wednesday Wednesday Wednesday Wednesday
26 may 23 June 28 July 25 August
2021 2021 2021 2021
Calendar of
novel imaging Joint Symposium PRo-Con The notch
approaches in with the eSC: debate receptors:
pulmonary The pulmonary session 1 multi-regulators
events...
hypertension circulation in the of PAh
patients heart failure development
syndrome
Wednesday Wednesday Wednesday Wednesday
PVRI webinars arranged in 2021
29 September 27 october 24 november 15 December
2021 2021 2021 2021
beyond DnA: Joint Symposium machine learning PRo-Con
The unseen with the IShLT: and artificial debate session 2:
Webinars take place on the last Wednesday of each month from genome and end-stage PAh intelligence medical vs surgical
15:00-17:00 GmT, so you can easily schedule these in your calendars. novel omics - how and what approaches for Ph: or interventional
approaches to do we do in From screening to therapy for
Click on each meeting for further information on chairs, speakers and presentation topics. Ph 2021? novel drug targets CTePh
PVRI
Pulmonary Vascular
Research Institute
Webinars
coming up in
Dates and topics for the webinar series in 2022:
2022 Wednesday
26 January
2022
Wednesday
23 February
2022
Wednesday
30 march
2022
Wednesday
27 April
2022
SAVe The DATeS
Vitual poster bone marrow Ageing and The association
discussion modulation of pulmonary between cancer
session 2 pulmonary hypertension: and Ph:
vascular An endemic on A tale of two
disease the horizon? diseases
Calendar of
events...
Wednesday
25 may
2022
Paediatric
Ph
PVRI webinars arranged in 2022
Webinars take place on the last Wednesday of each month from
15:00-17:00 GmT, so you can easily schedule these in your calendars.
Click on each meeting for further information on chairs, speakers and presentation topics.
Presentations
Webinar 1 If not all questions can be answered on the day,
Date // 27 January 2021
all comments will be published and circulated to all
participants after the webinar.
NOTE: All times indicated are Greenwich Mean Time (GMT)
Around the globe:
Global burden of pulmonary hypertension
Chairs & moderators: // Paul Corris UNIVERSITY OF NEWCASTLE, UK
// Stylianos Orfanos UNIVERSITY OF ATHENS MEDICAL SCHOOL, GREECE
// Rogerio Souza UNIVERSITY OF SAO PAULO, BRAZIL
// Helen Whitford THE ALFRED HOSPITAL, AUSTRALIA
Presentations 15:00-17:00
Introduction by Werner Seeger // Pvri PresiDent 2020-2022. Justus-Liebig university giessen, germany
The view of the World Heart Federation (WHF) 15:00-15:15
Presenter: // Fausto Pinto Lisbon meDicaL schooL, PortugaL & PresiDent eLect WorLD heaLth FeDeration 2019-20
Discussion 15:15-15:22
Right heart failure in Africa 15:22-15:37
Presenter: // ana olga mocumbi ministry oF heaLth, mozambique & co-chair oF the Lancet ncDi Poverty commission
Discussion 15:37-15:45
Update on the Global Burden of PH Project of the Institute for Health Metrics 15:45-16:00
and Evaluation (IHME)
Presenter: // sophia emmons-bell institute For heaLth metrics anD evaLuation (ihme), usa
Discussion 16:00-16:08
PVRI GoDeep: Perspectives of a global meta-registry 16:08-16:23
Presenter: // Werner seeger Justus-Liebig university giessen, germany
Discussion 16:23-16:30
Best abstract: Mortality of idiopathic/hereditary and connective tissue disease- 16:30-16:40
associated PAH: The data from first single center prospective registry in Indonesia
Presenter: // anggoro budi hartopo DePartment oF carDioLogy anD vascuLar meDicine, gaDJah maDa university, inDonesia
Discussion 16:40-16:45
Best abstract: Triple therapy in pulmonary arterial hypertension in an expert center 16:45-16:55
in Mexico City. Real-life results.
Presenter: // humberto garcia-aguilar nationaL meDicaL center, mexico city, mexico
Discussion 16:55-17:00
SUPPORTED B Y Back to
calendar
Congratulations go to
Niamh Errington
who has been awarded the Rupert Swift Award 2020 for her abstract entitled:
A diagnostic miRNA signature for pulmonary arterial hypertension using a consensus machine learning approach
Webinar 2
If not all questions can be answered on
If not all questions can be answered on the day,
the day, all comments will be published
all comments will be published and circulated to all
Date // 24 February 2021
and circulated to all participants after
participants after the webinar.
the webinar.
NOTE: All times indicated are Greenwich Mean Time (GMT)
Keynote lecture session 2021 including the Professor Sheila Glennis Haworth
Memorial Lecture
Presentations 15:00-17:00
Keynote lecture 1 15:00-15:30
Chairs & moderators: // Stefano Ghio IRCCS POLICLINICO SAN MATTEO FOUNDATION, ITALY
// Paul Yu BRIGHAM AND WOMEN'S HOSPITAL, HARVARD MEDICAL SCHOOL, USA
mHealth and wearables: Is this the dawn of a new age for cardiovascular medicine?
Presenter: // Martin Cowie IMPERIAL COLLEGE LONDON, UK
Discussion 15:30-15:40
Keynote lecture 2 15:40-16:10
Chairs & moderators: // Reda Girgis MICHIGAN STATE UNIVERSITY, USA
// Horst Olschewski MEDICAL UNIVERSITY OF GRAZ, AUSTRIA
Professor Sheila Glennis Haworth Memorial Lecture
Translational Research on Pulmonary Arterial Hypertension
Presenter: // Jason Yuan UNIVERSITY OF CALIFORNIA SAN DIEGO, USA
Discussion 16:10-16:20
Best Abstracts
Chairs & moderators: // Stefano Ghio IRCCS POLICLINICO SAN MATTEO FOUNDATION, ITALY
// Reda Girgis MICHIGAN STATE UNIVERSITY, USA
// Horst Olschewski MEDICAL UNIVERSITY OF GRAZ, AUSTRIA
// Paul Yu BRIGHAM AND WOMEN'S HOSPITAL, HARVARD MEDICAL SCHOOL, USA
Best abstract: Biomarker Analysis of the PULSAR Study: An Ongoing Phase 2, 16:20-16:28
Double-Blind, Placebo-Controlled, Randomized Study to Compare the Efficacy and
Safety of Sotatercept (ACE-011) Versus Placebo When Added to Standard of Care
for the Treatment of Pulmonary Arterial Hypertension (PAH)
Presenter: // MarcHumbert PARIS-SACLAY UNIVERSITY, FRANCE
Discussion 16:28-16:32
Best abstract: Switching from PDE5i to riociguat in patients with PAH: 16:32-16:40
The REPLACE Study
Presenter: // Raymond Benza OHIO STATE UNIVERSITY, USA
Discussion 16:40-16:44
Best abstract: A diagnostic miRNA signature for pulmonary arterial hypertension 16:44-16:52
Back to
using a consensus machine learning approach calendar
Presenter: // Niamh Errington SHEFFIELD INSTITUTE FOR TRANSLATIONAL NEUROSCIENCE, UK
Discussion 16:52-17:00
Presentations
Webinar 3 If not all questions can be answered on the day,
Date // 24 march 2021
all comments will be published and circulated to all
participants after the webinar.
NOTE: All times indicated are Greenwich mean Time (GMT)
Connection between CoVID-19 and pulmonary vascular disease
Chairs & moderators: // Sylvia Cohen-Kaminsky UNIVERSITÉ PARIS SACLAY, FRANCE
// Marion Delcroix UNIVERSITY HOSPITALS OF LEUVEN, BELGIUM
// TBC
Presentations 15:00-17:00
SARS-1, MERS, SARS-2 and more: Are coronavirus infections an ubiquitous 15:00-15:15
part of our lives?
Presenter: // Albert Osterhaus university OF veterinAry meDicine hAnnOver, germAny
Discussion 15:15-15:22
Endothelitis and aberrant angiogenesis: Mechanisms of COVID-19 induced 15:22-15.37
vascular injury
Presenter: // Danny Jonigk hAnnOver meDicAL schOOL, germAny
Discussion 15:37-15:45
Venous thromboembolism in COVID-19: Prevalence and clinical picture 15:45-16:00
Presenter: // stavros konstantinides university meDicAL center OF mAinz, germAny
Discussion 16:00-16:08
ACE-II receptors: Modulation of PVD in COVID-19? 16:08-16:23
Presenter: // Anna hemnes vAnDerbiLt university, usA
Discussion 16:23-16:30
Best abstract: Tricuspid regurgitation, as proxy for acute pulmonary hypertension, 16:30-16:40
and its association with short-term outcome in severe Covid-19
Presenter: // claes Frostell kArOLinskA institute At DAnDeryD hOsPitAL, sWeDen
Discussion 16:40-16:45
Best abstract: Venous and arterial thromboembolism in COVID-19: A systematic 16:45-16:55
review with meta-analysis
Presenter: // vicky mai quebec cArDiOLOgy AnD PuLmOnOLOgy reseArch center, LAvAL university, cAnADA
Discussion 16:55-17:00
back to
calendar
Congratulations go to
Prakash Chelladurai
who has been awarded the Butrous Young Investigator Award 2020 for his abstract entitled:
Epigenome-wide profiling uncovers novel gene regulatory networks in human pulmonary arterial hypertension
Webinar 4
if not all questions can be answered on
the day, all comments will be published
Date // 28 April 2021
and circulated to all participants after
the webinar.
notE: all times indicated are Greenwich Mean Time (GMt)
Virtual poster discussion session 1 Round 2 CLINICAL 16:00-17:00
Chairs & moderators: // christophe Guignabert
UnivErsité Paris-saclay, francE
// anton vonk noordegraaf
Presentations 15:00-17:00 aMstErdaM UnivErsity MEdical cEntEr, tHE nEtHErlands
// Khodr tello
JUstUs-liEBiG UnivErsity GiEssEn, GErMany
Round 1 BASIC 15:00-16:00 Poster 1: Equivalent outcomes for hereditary and idiopathic pulmonary arterial 16:00-16:05
Chairs & moderators: // Brian Graham UnivErsity of california san fransisco, Usa
// tim lahm indiana UnivErsity MEdical cEntEr, Usa hypertension in children; an analysis from a national australian registry
// Evangelos Michelakis UnivErsity of alBErta, canada Presenter: // katherine kearney graham UnIversIty of new soUtH wales, aUstralIa
Discussion 16:05-16:10
Poster 1: therapeutically targeting endothelial cell metabolic dysfunction in 15:00-15:05
Pulmonary arterial Hypertension with apigenin Poster 2: Effect of Macitentan across Prognostic age Groups in Patients with 16:10-16:15
Presenter: // Iona Cuthbertson Department of meDICIne, UnIversIty of CambrIDge, Uk Pulmonary arterial Hypertension (PaH)
Presenter: // richard Channick UnIversIty of CalIfornIa los angeles meDICal Center, Usa
Discussion 15:05-15:10
Discussion 16:15-15:20
Poster 2: Epigenome-wide profiling uncovers novel gene regulatory networks in 15:10-15:15
human pulmonary arterial hypertension Poster 3: validation of artificial intelligence artery-vein classification for 16:20-16:25
Presenter: // Prakash Chelladurai max-planCk-InstItUte for Heart anD lUng researCH, germany
contrast ct imaging in PH subjects
Presenter: // pietro nardelli brIgHam anD women's HospItal, HarvarD meDICal sCHool, Usa
Discussion 15:15-15:20
Discussion 16:25-16:30
Poster 3: implication of the Histone Methyltransferase “G9a” in Pulmonary arterial 15:20-15:25
Poster 4: Efficacy in Patient subgroups in the incrEasE trial, a Phase iii trial 16:30-16:35
Hypertension
to Evaluate inhaled treprostinil in Patients with Pulmonary Hypertension due to
Presenter: // Charifa awada tHe UnIversIty InstItUte of CarDIology anD pUlmonology of QUebeC, CanaDa
Parenchymal lung disease
Discussion 15:25-15:30
Presenter: // victor tapson CeDars-sInaI meDICal Cente, Usa
Discussion 16:35-16:40
Poster 4: Perinatal exposure to serotonin re-uptake inhibitor causes mild 15:30-15:35
pulmonary hypertension in adult female rats
Poster 5: acetazolamide and High altitude Pulmonary Edema Prevention 16:40-16:45
Presenter: // barbora kaftanová Department of pHysIology, CHarles UnIversIty seConD meDICal sCHool, CzeCH repUblIC
Presenter: // erik swenson UnIversIty of wasHIngton, Usa
Discussion 15:35-15:40 Discussion 16:45-16:50
Poster 5: Endothelial overexpression of sirt3 protects the metabolic etiology in PaH 15:40-15:45 Poster 6: telomeric tankyrases: a novel and propitious target to ameliorate the 16:50-16:55
Presenter: // anandharajan rathinasabapathy vanDerbIlt UnIversIty meDICal Centre, Usa maladaptation phenomena at Heights
Discussion 15:55-15:50 Presenter: // manjula miglani srm UnIversIty, Haryana, InDIa
Discussion 16:55-17:00
Poster 6: axl is a novel Modulator of Bone Morphogenetic Protein receptor 2 in 15:50-15:55
Pulmonary arterial Hypertension
Presenter: // tatyana novoyatleva JUstUs-lIebIg-UnIversIty gIessen, germany CME Credits
this event has been accredited by both the European accreditation council for
Back to
Discussion 15:55-16:00 continuing Medical Education (EaccME) and the European Board for accreditation in
Pneumology (EBaP). Physicians may convert EaccME® credits to an equivalent number
2 CME credits 2 CME credits
calendar
of aMa Pra category 1 creditstM.
Presentations
Webinar 5 If not all questions can be answered on the day,
Date // 26 may 2021
all comments will be published and circulated to all
participants after the webinar.
NOTE: All times indicated are Greenwich mean Time (GMT)
novel imaging approaches in pulmonary hypertension patients
Chairs & moderators: // David Kieley UNIVERSITY OF SHEFFIELD, UK
// David Levin MAYO CLINIC, USA
// Lan Zhao IMPERIAL COLLEGE LONDON, UK
Presentations 15:00-17:00
Update from the Fleischner Society Task Force for imaging in pulmonary 15:00-15:15
hypertension
Presenter: // martine remy university centre OF LiLLe, FrAnce
Discussion 15:15-15:24
Molecular imaging of pulmonary vascular disease using microvascular 15:24-15:39
endothelial cell ligands
Presenter: // Jocelyn Dupuis mOntreAL heArt institute, cAnADA
Discussion 15:39-15:48
MRI to assess pulmonary vascular changes and PH progression 15:48-16:03
Presenter: // Jens vogel-claussen hAnnOver meDicAL schOOL, germAny
Discussion 16:03-16:12
Xenon magnetic resonance imaging signatures of PH 16:12-16:27
Presenter: // sudarshan rajagopal Duke university meDicAL center, usA
Discussion 16:27-16:36
Synchrotron-based phase contrast micro-CT imaging of pulmonary vascular 16:36-16:51
disease in human tissue and animal models
Presenter: // karin tran-Lundmark LunD university, sWeDen
Discussion 15:51-17:00
back to
Cme Credits calendar
This event has been accredited by both the European Accreditation Council for
Continuing Medical Education (EACCME) and the European Board for Accreditation in 2 Cme credits 2 Cme credits
Pneumology (EBAP). Physicians may convert EACCME® credits to an equivalent number
of AMA PRA Category 1 CreditsTM.Presentations
Webinar 6 If not all questions can be answered on the day,
Date // 23 June 2021
all comments will be published and circulated to all
participants after the webinar.
NOTE: All times indicated are Greenwich mean Time (GMT)
Joint Symposium with the eSC:
The pulmonary circulation in the heart failure syndrome
Chairs & moderators: // Sophia Airhart UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE, USA
// Michele D´Alto MONALDI HOSPITAL, ITALY
// George Giannakoulas AHEPA UNIVERSITY HOSPITAL, GREECE
Presentations 15:00-17:00
The right ventricle in HFpEF 15:00-15:15
Presenter: // marco guazzi university OF miLAn, itALy
Discussion 15:15-15:22
Genetic aspects in Group2 PH 15:22-15.37
Presenter: // tbc
Discussion 15:37-15:45
Exercise haemodynamics in heart failure: What can we learn from invasive CPET? 15:45-16:00
Presenter: // gabor kovacs meDicAL university OF grAz, AustriA
Discussion 16:00-16:08
Systemic consequences and interorgan cross-talk in heart failure and PH 16:08-16:23
Presenter: // stephan rosenkranz university OF cOLOgne, germAny
Discussion 16:23-16:30
Best abstract: The Natriuretic Peptide Clearance Receptor Selectively Causes 16:30-16:40
Right Ventricular Dysfunction in a Model of Pulmonary Hypertension and Heart
Failure with Preserved Ejection Fraction
Presenter: // vineet Agrawal vAnDerbiLt university meDicAL center, usA
Discussion 16:40-16:45
Best abstract: N-Lysine methyltransferase Smyd2-mediated HIF-1A stabilization 16:45-16:55
plays a protective role in RV hypertrophy
Presenter: // swathi veeroju Justus-Liebig university, giessen, germAny
Discussion 16:55-17:00
back to
Cme Credits calendar
This event has been accredited by both the European Accreditation Council for
Continuing Medical Education (EACCME) and the European Board for Accreditation in 2 Cme credits 2 Cme credits
Pneumology (EBAP). Physicians may convert EACCME® credits to an equivalent number
of AMA PRA Category 1 CreditsTM.Presentations
Webinar 7 If not all questions can be answered on the day,
Date // 28 July 2021
all comments will be published and circulated to all
participants after the webinar.
NOTE: All times indicated are Greenwich mean Time (GMT)
PRo-Con debate session 1
Presentations 15:00-17:00
Topic A:
Role of pulmonary vascular pruning in PAh 15:00-16:00
Chairs & moderators: // Serpil Erzurum CLEVELAND CLINIC, USA
// Steeve Provencher LAVAL UNIVERSITY, CANADA
// Aaron Waxman BRIGHAM AND WOMEN'S HOSPITAL, HARVARD MEDICAL SCHOOL, USA
PRO: 15:00-15:15
A hopeless cause: The pulmonary vasculature is largely gone and
irredeemable in PAH
Presenter: // kurt stenmark university OF cOLOrADO Denver Anschutz, usA
rebuttal 15:30-15:35
CON: 15:15-15:30
Remnants of lost pulmonary vasculature may be re-engaged in PAH
Presenter: // Duncan stewart OttAWA hOsPitAL reseArch institute, cAnADA
rebuttal 15:35-15:40
general discussion 15:40-16:00
Topic b:
Treatment of patients with mild PAh 16:00-17:00
Chairs & moderators: // Paul Hassoun JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE, USA
// Allan Lawrie UNIVERSITY OF SHEFFIELD, UK
// Stuart Rich NORTHWESTERN UNIVERSITY FEINBERG SCHOOL OF MEDICINE, USA
// Zeenat Safdar HOUSTON METHODIST HOSPITAL, USA
PRO: 16:00-16:15
Patients with mild pulmonary hypertension (mPAP 21-24) should be
treated with PAH approved drugs
Presenter: // David systrom brighAm AnD WOmen's hOsPitAL, usA
rebuttal 16:30-16:35
CON: 16:15-16:30
Patients with mild pulmonary hypertension (mPAP 21-24) should NOT be
treated with PAH approved drugs
Presenter: // roham zamanian stAnFOrD university, usA
rebuttal 16:35-16:40
general discussion 16:40-17:00
back to
Cme Credits calendar
This event has been accredited by both the European Accreditation Council for
Continuing Medical Education (EACCME) and the European Board for Accreditation in 2 Cme credits 2 Cme credits
Pneumology (EBAP). Physicians may convert EACCME® credits to an equivalent number
of AMA PRA Category 1 CreditsTM.Presentations
Webinar 8 If not all questions can be answered on the day,
Date // 25 August 2021
all comments will be published and circulated to all
participants after the webinar.
NOTE: All times indicated are Greenwich mean Time (GMT)
The notch receptors:
multi-regulators of PAh development
Chairs & moderators: // Marc Humbert UNIVERSITÉ PARIS-SACLAY, FRANCE
// JinJiang Pang UNIVERSITY OF ROCHESTER MEDICAL CENTER, USA
// Rhian Touyz UNIVERSITY OF GLASGOW, UK
Presentations 15:00-17:00
Role of notch1 in experimental pulmonary hypertension 15:00-15:15
Presenter: // ralph schermuly Justus-Leibig university giessen, germAny
Discussion 15:15-15:30
Notch-BMPR interactions in endothelium in PAH 15:30-15:45
Presenter: // marlene rabinovitch stAnFOrD university, usA
Discussion 15:45-16:00
Notch3 is a driver and biomarker for PAH 16:00-16:15
Presenter: // Patricia thistlethwaite university OF cALiFOrniA sAn DiegO, usA
Discussion 16:15-16:30
Notch3 lineage and pulmonary vasculopathy 16:30-16:45
Presenter: // maya kumar stAnFOrD university schOOL OF meDicine, usA
Discussion 16:45-17:00
back to
Cme Credits calendar
This event has been accredited by both the European Accreditation Council for
Continuing Medical Education (EACCME) and the European Board for Accreditation in 2 Cme credits 2 Cme credits
Pneumology (EBAP). Physicians may convert EACCME® credits to an equivalent number
of AMA PRA Category 1 CreditsTM.Presentations
Webinar 9 If not all questions can be answered on the day,
Date // 29 September 2021
all comments will be published and circulated to all
participants after the webinar.
NOTE: All times indicated are Greenwich mean Time (GMT)
beyond DnA:
The unseen genome and novel omics approaches to Ph
Chairs & moderators: // Micheala Aldred INDIANA UNIVERSITY SCHOOL OF MEDICINE, USA
// Vinicio de Jesus Perez STANFORD UNIVERSITY, USA
// Nicholas Morrell UNIVERSITY OF CAMBRIDGE, UK
Presentations 15:00-17:00
MicroRNAs and IncRNAs in right heart hypertrophy and failure 15:00-15:15
Presenter: // sébastien bonnet LAvAL university, cAnADA
Discussion 15:15-15:24
LncRNA as biomarkers/therapeutic agents for pulmonary diseases 15:24-15:39
- prospective view
Presenter: // stephen chan university OF Pittsburgh, usA
Discussion 15:39-15:48
Epigenomics in pulmonary vascular remodelling 15:48-16:03
Presenter: // soni savai-Pullamsetti mAx PLAnck institute FOr heArt AnD Lung reseArch, germAny
Discussion 16:03-16:12
Multiomic tools for single cell analysis 16:12-16:27
Presenter: // Peter smibert neW yOrk genOme centre, usA
Discussion 16:27-16:36
Proteomics: From discovery research toward the clinic - novel AI perspectives? 16:36-16:51
Presenter: // christopher rhodes imPeriAL cOLLege LOnDOn, uk
Discussion 16:51-17:00
back to
Cme Credits calendar
This event has been accredited by both the European Accreditation Council for
Continuing Medical Education (EACCME) and the European Board for Accreditation in 2 Cme credits 2 Cme credits
Pneumology (EBAP). Physicians may convert EACCME® credits to an equivalent number
of AMA PRA Category 1 CreditsTM.Presentations
Webinar 10 If not all questions can be answered on the day,
Date // 27 october 2021
all comments will be published and circulated to all
participants after the webinar.
NOTE: All times indicated are Greenwich mean Time (GMT)
Joint symposium with the IShLT:
end-stage PAh - how and what do we do in 2021?
Chairs & moderators: // Paul Corris UNIVERSITY OF NEWCASTLE, UK
// Mardi Gomberg-Maitland GW UNIVERSITY MEDICINE AND HEALTH SCIENCES, USA
// Walter Klepetko MEDICAL UNIVERSITY OF VIENNA, AUSTRIA
Presentations 15:00-17:00
When should a PH patient be considered for lung transplant? 15:00-15:15
Presenter: // John granton tOrOntO generAL hOsPitAL, cAnADA
Discussion 15:15-15:24
Atrial septum defect creation or mechanical support for end-stage PAH 15:24-15:39
Presenter: // erika berman-rosenzweig cOLumbiA university meDicAL center, usA
Discussion 15:39-15:48
Lung and heart-lung transplant in 2021: How well do PAH patients do? 15:48-16:03
Presenter: // eugene golts university OF cALiFOrniA sAn DiegO, usA
Discussion 16:03-16:12
Pluripotent stem cell-based approaches and the future of artificial lungs 16:12-16:27
Presenter: // ulrich martin hAnnOver meDicAL schOOL, germAny
Discussion 16:27-16:36
Timing and extent of ventricular reverse remodelling after lung transplant 16:36-16:51
for PH
Presenter: // ryan tedford meDicAL university OF sOuth cArOLinA (musc), usA
Discussion 16:51-17:00
Supported by
back to
Cme Credits calendar
This event has been accredited by both the European Accreditation Council for
Continuing Medical Education (EACCME) and the European Board for Accreditation in 2 Cme credits 2 Cme credits
Pneumology (EBAP). Physicians may convert EACCME® credits to an equivalent number
of AMA PRA Category 1 CreditsTM.Presentations
Webinar 11 If not all questions can be answered on the day,
Date // 24 november 2021
all comments will be published and circulated to all
participants after the webinar.
NOTE: All times indicated are Greenwich mean Time (GMT)
machine learning and artificial intelligence approaches for Ph:
From screening to novel drug targets
Chairs & moderators: // Raymond Benza OHIO STATE UNIVERSITY, USA
// Mark Gladwin UNIVERSITY OF PITTSBURG MEDICAL CENTER, USA
// Martin Wilkins IMPERIAL COLLEGE LONDON, UK
Presentations 15:00-17:00
Looking beyond the hype: Applied AI and machine learning in translational 15:00-15:15
medicine
Presenter: // Dennis Wang university OF sheFFieLD, uk
Discussion 15:15-15:22
Computational network pharmacology in cardiovascular disease: Leveraging 15:22-15:37
big data
Presenter: // Joseph Loscalzo hArvArD university, usA
Discussion 15:37-15:45
Drug discovery using artificial intelligence engines: Challenges and opportunities 15:45-16:00
Presenter: // tbc
Discussion 16:00-16:08
Utilising artificial intelligence to screen and diagnose iPAH 16:08-16:23
Presenter: // David kiely university OF sheFFieLD, uk
Discussion 16:23-16:30
Best abstract: Biological heterogeneity in idiopathic pulmonary arterial hypertension 16:30-16:40
identified through unsupervised transcriptomic profiling of whole blood
Presenter: // sokratis kariotis university OF sheFFieLD, uk
Discussion 16:40-16:45
Best abstract: Transcriptomic characterization of Pulmonary arterial hypertension 16:45-16:55
on pathway level
Presenter: // yajing Ji PhArmAcOLOgy AnD tOxicOLOgy DePArtment,michigAn stAte university, usA
Discussion 16:55-17:00
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Cme Credits calendar
This event has been accredited by both the European Accreditation Council for
Continuing Medical Education (EACCME) and the European Board for Accreditation in 2 Cme credits 2 Cme credits
Pneumology (EBAP). Physicians may convert EACCME® credits to an equivalent number
of AMA PRA Category 1 CreditsTM.Presentations
Webinar 12 If not all questions can be answered on the day,
Date // 15 December 2021
all comments will be published and circulated to all
participants after the webinar.
NOTE: All times indicated are Greenwich mean Time (GMT)
PRo-Con debate session 2:
medical vs. surgical or interventional therapy for CTePh
Chairs & moderators: // Irene Lang MEDICAL UNIVERSITY OF VIENNA, AUSTRIA
// Bradley Maron BRIGHAM AND WOMEN'S HOSPITAL, HARVARD MEDICAL SCHOOL, USA
// Belinda Rivera-Lebron THE UNIVERSITY OF PITTSBURGH MEDICAL CENTER, USA
// Gérald Simonneau UNIVERSITÉ PARIS-SACLAY, FRANCE
Presentations 15:00-17:00
PRo: Riociguat should be given to all CTEPH patients, regardless of timing of PEA/BPA 15:00-15:15
Presenter: // Ardeschir ghofrani Justus-Liebig university OF giessen, germAny
rebuttal 15:30-15:35
Con: Riociguat should be given only to patients with inoperable or residual 15:15-15:30
CTEPH after PEA/BPA
Presenter: // hiromi matsubara OkAyAmA meDicAL center, JAPAn
rebuttal 15:35-15:40
general discussion 15:40-16:00
Best abstract: Systematic follow-up of patients following acute pulmonary 16:05-16:10
embolism is associated with an increased incidence of Chronic Thromboembolic
Pulmonary Hypertension and less severe disease
Presenter: // charlotte Durrington sheFFieLD PuLmOnAry vAscuLAr DiseAse unit, uk
Discussion 16:10-16:15
Best abstract: Women and chronic thromboembolic pulmonary hypertension. 16:15-16:20
The special meaning of balloon pulmonary angioplasty
Presenter: // Alejandro cruz utrilla cArDiOLOgy DePArtment, university hOsPitAL, mADriD, sPAin
Discussion 16:20-16:25
Best abstract: G protein-coupled receptor expression from single cell RNA 16:25-16:30
sequencing in chronic thromboembolic pulmonary hypertension
Presenter: // gayathri viswanathan DePArtment OF cArDiOLOgy, Duke university meDicAL center, usA
Discussion 16:30-16:35
Best abstract: Study of the antifibrotic action of JAK inhibitors for the prevention 16:35-16:40
and treatment of chronic thromboembolic pulmonary hypertension
Presenter: // Andrei karpov ALmAzOv nAtiOnAL meDicAL reseArch centre, russiA
Discussion 16:40-16:45
Best abstract: Unilateral Chronic Thromboembolic Pulmonary Disease: 16:45-16:50
Do they benefit from surgery? Cme Credits
Presenter: // Farid rashidi tAbriz university OF meDicAL sciences, irAn This event has been accredited by both the European Accreditation Council for
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Discussion 16:50-16:55
Continuing Medical Education (EACCME) and the European Board for Accreditation in 2 Cme credits 2 Cme credits
Pneumology (EBAP). Physicians may convert EACCME® credits to an equivalent number calendar
of AMA PRA Category 1 CreditsTM.Presentations
Webinar 13 If not all questions can be answered on the day,
Date // 26 January 2022
all comments will be published and circulated to all
participants after the webinar.
NOTE: All times indicated are Greenwich mean Time (GMT)
Virtual poster discussion session 2 Round 2 - CLInICAL 16:10-17:10
Chairs & moderators: // Joan-Albert Barbérà
HOSPITAL CLINIC DE BARCELONA, SPAIN
Presentations 15:00-17:10 // Bradley Maron
BRIGHAM AND WOMEN'S HOSPITAL, HARVARD MEDICAL SCHOOL, USA
// Victor Tapson
1
Round 1 - bASIC 15:00-16:10 CEDARS-SINAI MEDICAL CENTER CALIFORNIA, USA
Chairs & moderators: // Peter Dorfmüller JUSTUS-LIEBIG UNIVERSITY GIESSEN, GERMANY
// Max Gassmann UNIVERSITY OF ZURICH, SWITZERLAND
// Mark Geraci UNIVERSITY OF PITTSBURG, USA Poster 1: Association between Leflunomide and Pulmonary Hypertension 16:10-16:15
Presenter: // thomas Lacoste Palasset PAris-sAcLAy university, FrAnce
Poster 1: Novel TRAF2 variant and KDR deletion are implicated in the 15:00-15:05 Discussion 16:15-16:20
pathogenesis of pulmonary arterial hypertension
Presenter: // Jair tenorio LA PAz university hOsPitAL, sPAin Poster 2: The Estimand Framework in PAH Clinical Trials 16:20-16:25
Discussion 15:05-15:10 Presenter: // youlan rao uniteD therAPeutics cOrP, usA
Poster 2: GP130 Signaling Promotes Right Ventricular Dysfunction in Pulmonary 15:10-15:15 Discussion 16:25-16:30
Arterial Hypertension Via Microtubules
Presenter: // sasha Prisco cArDiOvAscuLAr DivisiOn, LiLLehei heArt institute, university OF minnesOtA, usA Poster 3: Risk stratification in pulmonary hypertension due to chronic obstructive 16:30-16:35
Discussion 15:15-15:20 pulmonary disease
Presenter: // Athiththan yogeswaran Justus-Liebig-university giessen, germAny
Poster 3: Loss of Estrogen Receptor Alpha (ERα) Worsens Hemodynamic 15:20-15:25 Discussion 16:35-16:40
Alterations and Right Ventricular (RV) Adaptation in Female Rats with Pulmonary
Hypertension (PH)
Poster 4: Small pulmonary vessels in severe pulmonary hypertension associated 16:40-16:45
Presenter: // Andrea Frump inDiAnA university schOOL OF meDicine, usA
with chronic lung disease
Discussion 15:25-15:30 Presenter: // Dheyaa Alkhanfar university OF sheFFieLD, uk
Poster 4: Breast cancer and heritable PAH due to BMPR2 mutation: 15:30-15:35 Discussion 16:45-16:50
An unexpected discovery
Presenter: // victoria toro quebec university institute OF cArDiOLOgy AnD PneumOLOgy, cAnADA Poster 5: A Phase 1, open-label, crossover study of inhaled seralutinib to assess 16:50-16:55
Discussion 15:35-15:40 potential effects on the pharmacokinetics (PK) of cytochrome P450 (CYP) and
transporter substrates in healthy subjects
Poster 5: Smooth Muscle Tsc2 deficiency leads to spontaneous pulmonary 15:40-15:45 Presenter: // Jack Li gOssAmer biO, inc., sAn DiegO, usA
hypertension and represents attractive molecular target for therapeutic intervention
Discussion 16:55-17:00
Presenter: // steven yuanjun shen schOOL OF meDicine, university OF cALiFOrniA, DAvis, usA
Discussion 15:45-15:50 Poster 6: Cardiac MRI and risk stratification in pulmonary arterial hypertension:
Poster 6: Identification of ADORA1-PDE10A Complex Formation and Its 15:50-15:55 Evaluation of ESC/ERS thresholds for right atrial area 17:00-17:05
Bidirectional Regulation of Intracellular Cyclic AMP Levels as a Novel Therapeutic Presenter: // Faisal Alandejani university OF sheFFieLD, uk
Presenter: // chanil valasarajan mAx-PLAnck-institute FOr heArt AnD Lung reseArch, germAny Discussion 17:05-17:10
Discussion 15:45-15:50
Poster 7: Downregulation of adenylate kinase 4 (AK4) improves the mitochondrial 16:00-16:05
respiration and inhibits the glycolytic switch of pulmonary arterial smooth muscle cells Cme Credits
Presenter: // tessa Wilke Justus-Liebig university giessen, germAny
This event has been accredited by both the European Accreditation Council for
Continuing Medical Education (EACCME) and the European Board for Accreditation in
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2 Cme credits 2 Cme credits
calendar
Discussion 16:05-16:10
Pneumology (EBAP). Physicians may convert EACCME® credits to an equivalent number
of AMA PRA Category 1 CreditsTM.Presentations
Webinar 14 If not all questions can be answered on the day,
Date // 23 February 2022
all comments will be published and circulated to all
participants after the webinar.
NOTE: All times indicated are Greenwich mean Time (GMT)
bone marrow modulation of pulmonary vascular disease
Chairs & moderators: // James Klinger BROWN UNIVERSITY, USA
// Edda Spiekerkoetter STANFORD UNIVERSITY, USA
// Rebecca Vanderpool UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE, USA
Presentations 15:00-17:00
Role of bone marrow in the pathogenesis of PAH 15:00-15:15
Presenter: // tbc
Discussion 15:15-15:24
Role of bone marrow in the right ventricle remodelling 15:24-15:39
Presenter: // gaurav choudhary PrOviDence vA meDicAL center, usA
Discussion 15:39-15:48
Reversal of PH by whole bone marrow transplantation in BMPR2 deficient mice 15:48-16:03
Presenter: // James West vAnDerbiLt university meDicAL center, usA
Discussion 16:03-16:12
Bone marrow dependency of cigarette smoke-induced PH versus emphysema 16:12-16:27
Presenter: // norbert Weissmann Justus-Liebig university OF giessen, germAny
Discussion 16:27-16:36
Homologous bone marrow transplantation prevents the development of PAH 16:36-16:51
in patients with severe scleroderma
Presenter: // Jason Weatherald university OF cALgAry, cAnADA
Discussion 16:51-17:00
back to
Cme Credits calendar
This event has been accredited by both the European Accreditation Council for
Continuing Medical Education (EACCME) and the European Board for Accreditation in 2 Cme credits 2 Cme credits
Pneumology (EBAP). Physicians may convert EACCME® credits to an equivalent number
of AMA PRA Category 1 CreditsTM.Presentations
Webinar 15 If not all questions can be answered on the day,
Date // 30 march 2022
all comments will be published and circulated to all
participants after the webinar.
NOTE: All times indicated are Greenwich mean Time (GMT)
Ageing and pulmonary hypertension:
An endemic at the horizon?
Chairs & moderators: // John Newman VANDERBILT UNIVERSITY MEDICAL CENTER, USA
// Paul Williams CENTRE FOR CHEST DISEASE AND CRITICAL CARE, SOUTH AFRICA
// TBC
Presentations 15:00-17:00
Age-dependent prevalence of PH in the general population 15:00-15:15
Presenter: // harm Jan bogaard vu university meDicAL center AmsterDAm, the netherLAnDs
Discussion 15:15-15:22
Senescence mechanisms and pulmonary vascular aging 15:22-15.37
Presenter: // serge Adnot henri mOnDOr hOsPitAL, FrAnce
Discussion 15:37-15:45
Metabolic syndrome and obesity leads to age-related PH 15:45-16:00
Presenter: // imad Al ghouleh university OF Pittsburgh, usA
Discussion 16:00-16:08
Genetics and epigenetics in age-related PH 16:08-16:23
Presenter: // stephen Archer queen's university, cAnADA
Discussion 16:23-16:30
Best abstract: Right heart catheterization is underused in elderly patients 16:30-16:50
suspected of pulmonary hypertension
Presenter: // samara Jansen AmsterDAm umc, netherLAnDs
Discussion 16:50-17:00
back to
Cme Credits calendar
This event has been accredited by both the European Accreditation Council for
Continuing Medical Education (EACCME) and the European Board for Accreditation in 2 Cme credits 2 Cme credits
Pneumology (EBAP). Physicians may convert EACCME® credits to an equivalent number
of AMA PRA Category 1 CreditsTM.Presentations
Webinar 16 If not all questions can be answered on the day,
Date // 27 April 2022
all comments will be published and circulated to all
participants after the webinar.
NOTE: All times indicated are Greenwich mean Time (GMT)
The association between cancer and Ph:
A tale of two diseases
Chairs & moderators: // Elena Goncharova UNIVERSITY OF PITTSBURGH, USA
// Qadar Pasha ASIAN-PACIFIC SOCIETY FOR MOUNTAIN MEDICINE, INDIA
// Marlene Rabinovitch STANFORD UNIVERSITY, USA
Presentations 15:00-17:00
Cancer induced PH: Embolism as a major inducer 15:00-15:15
Presenter: // tbc
Discussion 15:15-15:22
Cancer induced PH: Microenvironmental cancer niche as a major inducer 15:22-15:37
Presenter: // rajkumar savai mAx PLAnck institute FOr heArt AnD Lung reseArch, germAny
Discussion 15:37-15:45
Cancer therapies induced PH 15:45-16:00
Presenter: // Frédéric Perros université PAris-suD, FrAnce
Discussion 16:00-16:08
Cancer related signalling mechanisms underlying PH development 16:08-16:23
Presenter: // Olivier boucherat LAvAL university, cAnADA
Discussion 16:23-16:30
Best abstract: FOXO3: A new potential therapeutic target in Pulmonary Arterial 16:30-16:40
Hypertension
Presenter: // yann grobs LAvAL university, cAnADA
Discussion 16:40-16:45
Best abstract: Non-invasive surrogate markers of PH are associated with poor 16:45-16:55
survival in lung cancer patients
Presenter: // michael cekay Justus-Liebig university giessen, germAny
Discussion 16:55-17:00
back to
Cme Credits calendar
This event has been accredited by both the European Accreditation Council for
Continuing Medical Education (EACCME) and the European Board for Accreditation in 2 Cme credits 2 Cme credits
Pneumology (EBAP). Physicians may convert EACCME® credits to an equivalent number
of AMA PRA Category 1 CreditsTM.Presentations
Webinar 17 If not all questions can be answered on the day,
Date // 25 may 2022
all comments will be published and circulated to all
participants after the webinar.
NOTE: All times indicated are Greenwich mean Time (GMT)
Professor Sheila Glennis haworth memorial Symposium
on Paediatric Ph
Chairs & moderators: // Mandy Maclean MBE, STRATHCLYDE INSTITUTE OF PHARMACY AND BIOMEDICAL SCIENCES, UK
// Shahin Moledina GREAT ORMOND STREET HOSPITAL, UK
// Anita Saxena ALL INDIA INSTITUTE OF MEDICAL SCIENCES, INDIA
Presentations 15:00-17:00
Genetics of pulmonary arterial hypertension: What we can learn by studying 15:00-15:15
children with and without congenital heart disease
Presenter: // Wendy chung university OF cOLumbiA, usA
Discussion 15:15-15:22
Therapeutic options in advanced PVD: Potts shunt versus lung transplantation 15:22-15:37
Presenter: // mark grady WAshingtOn university schOOL OF meDicine in st. LOuis, usA
Discussion 15:37-15:45
Stem cells and regenerative medicine for neonatal lung disease: Implications 15:45-16:00
for COPD
Presenter: // bernard thebaud the OttOWA hOsPitAL, cAnADA
Discussion 16:00-16:08
Assessment of operability in patients with congenital heart disease and PAH: 16:08-16:23
Fallacies and pitfalls
Presenter: // erika b. rosenzweig cOLumbiA university meDicAL center, usA
Discussion 16:23-16:30
Best abstract: The impact of chronic pulmonary hypertension on ventricular 16:30-16:40
function in extremely premature infants
Presenter: // gabriela de carvalho nunes mcgiLL university heALth centre, mOntreAL chiLDren’s hOsPitAL, cAnADA
Discussion 16:40-16:45
Best abstract: Improving guidance for the correctability of congenital cardiovascular 16:45-16:55
shunts with increased pulmonary vascular resistance
Presenter: // ronald Day university OF utAh, DePArtment OF PeDiAtrics, usA
Discussion 16:55-17:00
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Cme Credits calendar
This event has been accredited by both the European Accreditation Council for
Continuing Medical Education (EACCME) and the European Board for Accreditation in 2 Cme credits 2 Cme credits
Pneumology (EBAP). Physicians may convert EACCME® credits to an equivalent number
of AMA PRA Category 1 CreditsTM.Step into the PVRI
Digital Clinic...
...and claim CME credits.
PVRI
Pulmonary Vascular
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www.pvrinstitute.org
The PVRI is a Registered Charity in the UK, No: 1127115.
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