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Table of Contents Home CBMSO Science and Society Department José Antonio López Guerrero Science and Society Department
Next Science and Society Department Table of Contents Section Contents Home CBMSO Science and Society Department Research Summary Within the framework of the CBMSO Scientific Culture Program, The Department of Scientific Culture of the CBMSO (DCC-CBMSO) has collaborated in the following activities (2013-14): 1) XIII (2013) and XIV (2014) Scientific Weeks in Madrid. In this regard, several projects were carried out in the CBMSO –some of them fi- nancially supported by FECYT (Spanish Foundation for Science and Technology)-, complementing the annual program of guided visits of Secondary School students to our Research Centre. The CBMSO is one of the most active Centres of the CSIC and UAM (Spanish Board of Scientific Research) in such tasks. 2) Collabora- Exit tion with the Science and Society Madri+d Programme, involving the management of a scientific and cultural Blog (awarded by the Autonomous Community of Madrid in 2012) and the providing of several information for the scientific e-diary “Notiweb” (http://www.madrimasd.org/cienciaysociedad). 3) Developing of an Insti- tutional Facebook and Twitter Website “Departamento de Cultura Científica. Centro de Biología Molecular” and a weekly-updated Institutional Website about Social Communication of Science (http://web4.cbm.uam.es/ joomla-rl/index.php/es/servicios/cultura-cientifica?id=1175). 4) Weekly Mi+dTV and UNEDtv Scientific Culture Programme “3x3 TV news” (http://www.madrimasd.org/informacionidi/madrimasd-tv/default.asp). Research Summary 5) Participation in several seminars in High Schools and Secondary School Centers. 6) Participation in the Madrid Science Fair “Alcobendas Weekend Science Fair 2014”. 7) Organization (2013-2014) and coordina- tion of the “Biotechnology Explorer” course for secondary school teachers. 8) Finally, as a CBMSO member, Staff the DCC Director periodically colaborates with the magazine “El Cultural”, The Journal of Feelsynapsis and Principia –aimed to items of scientific culture -, the Spanish National TV (TVE; La 2), the Spanish National Radio (Radio 5 –“Entre Probetas” and “El Laboratorio de JAL”-, Radio 1 –“A Hombros de Gigantes- and Radio Publications Exterior –“Marca España”-) and Radio Utopía. Further information: http://web4.cbm.uam.es/joomla-rl/index.php/es/servicios/cultura-cientifica Moreover, the research group of NeuroVirology aims at the study of the effect of HSV-1 on neurodegeneration, demyelinating disease and transcytosis in both immature and differentiated myelin-producing oligodendrocytic cells. In addition to cell susceptibility the role of the major cell receptors for viral entry was assessed. In gene- ral, the results revealed that OPC (oligodendrocyte precursor cells) and HOG cells cultured under differentia- CBMSO 2013-2014 tion conditions became more susceptible to HSV-1. On the other hand, viral infection induced morphological changes corresponding to differentiated cells, suggesting that HSV-1 might be inducing cell differentiation. Colocalization of HVEM and nectin-1 with viral particles were also observed, suggesting that these two major HSV-1 receptors are functional in HOG cells. Finally, electron microscopy assays indicated that HSV-1 may be also entering OLs by macropinocytosis depending on their differentiation stage.
Previous Next Science and Society Department Table of Contents Section Contents Home CBMSO Science and Society Department Exit Research Summary Staff Figure 1. Participation in the Madrid Science Fair “Alcobendas Weekend Science Fair 2014” Publications Figure 2. Infection of oligodendrocytes by HSV-1 CBMSO 2013-2014
Previous Next Science and Society Department Table of Contents Section Contents Home CBMSO Science and Society Department Director: Exit José Antonio López Guerrero Technical Secretariat: Almudena Hernando Bellido Scientific Staff: Research Summary Antonio Jesús Crespillo Alguacil Staff Collaborators: Florencia Cavodeassi Madarro Elena Campos Sánchez Publications CBMSO 2013-2014
Previous Science and Society Department Table of Contents Section Contents Home CBMSO Science and Society Department Publications Bello-Morales R, Antonio Jesús Crespillo, Beatriz García, Luis Ángel Dorado, Beatriz Martín, Enrique Tabarés, Claude Krummenacher, Fernando de Castro and López-Guerrero JA. (2014). “The effect of cellular differentia- tion on HSV-1 infection of oligodendrocytic cells”. PLoS One. 9:e89141. Delgado-García M, Matesanz F, Alcina A, Fedetz M, García-Sánchez MI, Ruiz-Peña JL, Fernández O, Pinto Medel MJ, Leyva L, Arnal C, Delgado C, López Guerrero JA, González-Pérez A, Sáez ME, Villar LM, Alvarez- Cermeño JC, Picón C, Arroyo R, Varadé J, Urcelay E, Izquierdo G1, Lucas M. (2014) “ A new risk variant for multiple sclerosis at the immunoglobulin heavy chain locus associates with intrathecal IgG, IgM index and oligoclonal bands”. Mult.Scler. Nov 12. pii: 1352458514556302. Exit Social communication of science: Campos, E., López-Guerrero, J.A. (2013) “Células madre. Un futuro cada vez más cercano (II)”. Journal of Feelsynapsis 11:86-91 López-Guerrero, J.A. (2013). “Ciencia Exprés”. Ed. Elam. ISBN: 978-84-936585-3-3. Campos, E., López-Guerrero, J.A. (2013) “Células madre. Un futuro cada vez más cercano (III)”. Journal of Feelsynapsis 12:10-17 Research Summary Campos, E., López-Guerrero, J.A. (2013) “Células madre. Un futuro cada vez más cercano (III)”. Journal of Feelsynapsis 13:11-13 Staff López-Guerrero, J.A. (2013). “El experimento más importante se realiza sin controles”. Journal of Feelsy- napsis, 13:39-48. López Guerrero, J.A. and Bernardo Herradón (2013). “Breakthrough of the Year”. An. Quím. 109(4), 355–362. Publications López Guerrero, J.A. and Bernardo Herradón. (2014). “Hitos científicos de 2013”. Journal of Feelsynapsis, 14: 60-72. López-Guerrero, J.A. (2014). “38th Annual International Herpesvirus Workshop 2014”. Virología, 17:26-27. ..... López-Guerrero, J.A. El Cultural: 11/01/2013 “Nuevos virus, viejas infecciones” 01/03/2013 “La familia SARS ataca de nuevo” CBMSO 2013-2014 16/05/2013 “Clonación terapéutica versus clonación humana” 17/05/2013 “La gripe aviar no da respiro” 05/07/2013 “La genética pone al cáncer contra las cuerdas” 20/09/2013 “Sí, es una cuestión de sexo”… 08/11/2013 “Virus, de patógeno a herramienta” 27/12/2013 “Hitos del 2013” 28/02/2014 “De la Esclerosis Múltiple a la enfermedad de Crohn” 23/05/2014 “Ébola, MERS, Dengue… Guía viva de los virus” 12/08/2014 “Los puntos calientes del Ébola” 26/12/2014 “ Hitos del 2014”
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