SATURDAY, APRIL 17, 2021 - Bucknell University
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A VIRTUAL EVENT SATURDAY, APRIL 17, 2021
INTRODUCTION SPRING 2021 Welcome to the twentieth annual Kalman Research Symposium. An important central element of the Bucknell experience is to offer our students in all disciplines the opportunity to engage in substantive out-of-the-classroom research and creative projects with faculty. As stated in the mission statement for Bucknell’s Program for Undergraduate Research, these opportunities allow students and faculty to participate in collaborative learning processes designed to dissolve the distinction between teaching and research, and to create a community of learners in which scholarship serves as the basis for teaching and learning. This symposium showcases the breadth and variety of undergraduate research taking place at Bucknell, as is evidenced by the abstracts of the projects contained herein. Visitors are encouraged to visit the Kalman Symposium website, containing students’ posters, slides and recorded presentations, and to attend virtually the live symposium on April 17, 2021 to observe both the poster and oral presentations, as well as the poster sessions to interact with the student scholars and to learn more about their work. This symposium is named in honor of Ernest Kalman, who graduated from Bucknell in 1956. In addition to his service as a University trustee, Ernie’s generosity to his alma mater has taken many forms, one of which was a significant gift in support of undergraduate research. The Kalman Research Symposium features projects sponsored or supported by the following: n Bobko-Dennis Fund for Undergraduate Student Research n California Healthcare Undergraduate Research n Clare Boothe Luce Research Scholarship n College of Engineering n Culliton Family Fund for Undergraduate Research n David Burpee Endowment n Dean’s Fund for Summer Undergraduate Research in STEM n Degenstein Foundation ‐ Susquehanna Watershed Aquatic Ecology Research n Department of Biology n Department of Biomedical Engineering n Department of Chemistry n Department of Electrical & Computer Engineering n Department of Geology & Environmental Geosciences n Department of Geology & Environmental Geosciences Marchand Fund n Diane Hymas Undergraduate Research n Douglas K. Candland Undergraduate Research Fund n Drs. Anthony and Joyce D. Kales Undergraduate Research Fund n Emerging Scholars Program n Fund for Undergraduate Research in Biological and Chemical Sciences n G ary A. and Sandra K. Sojka Fund for Research, Teaching and Scholarship in Developmental Disabilities, Neuroscience & Human Health n Graduate Summer Research Fellowship n Grand Challenges Scholars Program BU C K N E L L U N I VE R SIT Y 1
The Kalman Research Symposium features projects sponsored or supported by the following: (continued) n Harold W. Heine Undergraduate Research Fund in Chemistry n Helen E. Royer Undergraduate Research Fund n James L.D. and Rebecca Roser Research Fund n Joann E. Walthour Undergraduate Research Fund n John C. Hoover Undergraduate Math Research n John M. Hustler Undergraduate Research Fund n Juliet Shield-Taylor Fund for Undergraduate Research n Kalman Fund for Biomedical Research Fellows n Kalman Fund for Undergraduate Research in the Sciences n Leanne Freas Trout Fund for Research and Teaching in French and Francophone Studies n Manning Intern Botanical Science n Mayfield and Johnson Scholarship n Michael Baker Jr. Summer Research Program n NASA Astrobiology Institute n National Institutes of Health n National Program for Playground Safety, University of Northern Iowa n National Science Foundation Grant (NSF) n (National Science Foundation) NSF ADVANCE n Organic Syntheses Summer Research Grant n PA Wild Resource Conservation Program n P IC Math, a Mathematical Association of America (MAA) program funded by the National Science Foundation (NSF) and the National Security Agency (NSA) n PPL Undergraduate Research Fund n Presidential Fellowship n PricewaterhouseCoopers Research Fund n Program for Undergraduate Research n Reed-Garman Award Fund for Engineering Entrepreneurship n Robert P. Vidinghoff Memorial Summer Internship n Schotz Family Fund n Scott AE - Research Fund n Senior Design and Research Sponsorship n Sigma Xi Grant-in-Aid of Research n Slonaker Fund n STEM Scholars n Stephen Glenn Hobar Memorial Research Award n Susquehanna River Heartland Coalition for Environmental Studies n Susquehanna River Research Program - Degenstein Foundation n Tague Family Fund for Undergraduate Research in Biomedical, Biological and Biochemical Sciences n The Katherine Mabis McKenna Environmental Internship Program n The Tom Greaves Fund for Research and Curricular Development n Thomas Spitzer Undergraduate Research Fund n Undergraduate Research in Animal Behavior 2 KA LMA N RESEAR C H S Y M PO S I UM
Akil Atkins ’22 Weiru Chen ’21 Caroline Eckert ’21, Amber Coleman Faculty Mentor: Professor Christopher Faculty Mentor: Professor Hava ’21, Alexis Faria ’22, Clara Han ’21, Dancy, COMPUTER SCIENCE Turkakin, PHYSICS & ASTRONOMY Makenna Luzenski ’23, Lauren Shearer Funding Source: National Science Funding Source: Undergraduate Research ’22 and Grace Wilder ’21 Foundation Grant (NSF) Advisory Council Faculty Mentor: Professor Chris Catch The Pig! Understanding Investigations of Kelvin- Boyatzis, PSYCHOLOGY the Interaction Between Helmholtz Instability (KHI) and Funding Source: Program for People and AI Associated Magnetosonic Wave Undergraduate Research Emission in the Solar Corona: Native Danish Mother’s Genevieve Block ’22 New Impacts on Coronal Intersection Between Faculty Mentor: Professor Shaunna Heating Parenting Approach and Barnhart, GEOGRAPHY Religion Funding Source: American Association of Ian Coates ’21 Geographers Faculty Mentor: Professor Kenneth Kyle Ferguson ’21 Homelessness Awareness and Mineart, CHEMICAL ENGINEERING Faculty Mentor: Professor Thomas Response in Shamokin, PA Funding Source: College of Engineering; Solomon, PHYSICS & ASTRONOMY National Science Foundation Grant (NSF) Funding Source: NSF Grant DMR- Emily Brandes ’21 Assessing the Impact of Block- 1806355, NSF Grant CMMI-1825379 Faculty Mentor: Professor Scott Meinke, Selective Homopolymers Noise-Driven Aggregation of POLITICAL SCIENCE on the Diffusion of Payload Swimmers in the Kolmogorov Funding Source: Honors Thesis in Through Polymeric Organogels Flow Political Science Julian Cohen ’21 To Believe or Not to Believe: A Mackenzie Flynn and Faculty Mentor: Professor Christopher Closer Look at the Impact of Bree McCullough ’22 Daniel, GEOLOGY & ENVIRONMENTAL Sexual Assault in Politics Faculty Mentor: Professor Ben GEOSCIENCES Hayes, WATERSHED SCIENCES AND Funding Source: Program for Ryan Bremer ’22 ENGINEERING PROGRAM Undergraduate Research Faculty Mentor: Professor Ken Funding Source: United States Forest Eisenstein, English - Film/Media Studies Determining the Metamorphic Service Funding Source: Dalal Innovation and Conditions of ca 1.4 Ga Rocks Little Arnot Run: An Evaluation Creativity Grant for Student-Faculty from the Sierra Estrella of Groundwater-Surface Water Collaboration Mountains, Arizona USA: Interactions with Regard Brakhage’s Adjacents An Application of Raman to Hyporheic Exchange and Thermobarometry Temperature Ella Carlander ‘22 and Michael Duncan ’23 Maya Freeman ’23 Michael Bolish ‘23 Faculty Mentor: Professor Douglas Faculty Mentor: Professor Cecilia Bove, Faculty Mentor: Professor Katharina Collins, CHEMISTRY BIOLOGY Vollmayr-Lee, PHYSICS & ASTRONOMY Funding Source: Presidential Fellowship Funding Source: Department of Biology Funding Source: National Science Gas-Phase Chemical Ionization Foundation Grant (NSF) Fluoroquinolone-based Orbitrap Mass Spectrometry Therapy and Onset of Computer Simulations of Granular Media Functional Gastrointestinal Olivia Dyer ’22 Disorders in Human Subjects Faculty Mentor: Professor Benjamin Edward Chen ’22 Wheatley, MECHANICAL ENGINEERING Keith Grega ’21 Faculty Mentor: Professor Joshua Funding Source: The John P. & Mary Jane Faculty Mentor: Professor Benjamin Stough, COMPUTER SCIENCE Swanson Professorship in Engineering & Wheatley, MECHANICAL ENGINEERING Funding Source: Ciffolillo Healthcare the Sciences Funding Source: Bucknell-Geisinger Technology Inventors Program Visual and Mechanical Research Initiative Assessing the Generalizability Characterization of the Muscle of Temporally Coherent Impact of Screw Type on to Aponeurosis Junction Torque During SCFE Screw Echocardiography Video Segmentation Removal Gari Eberly ’21 Faculty Mentor: Professor Katherine Jacob Feuerstein ’22 Hays, ENGLISH; CREATIVE WRITING Faculty Mentor: N/A Funding Source: N/A Funding Source: N/A Synthesis The Choppy Purple Surf: Understanding the 2020 Election in Rural Pennsylvania BU C K N E L L U N I VE R SIT Y 3
Emily Haas ’21 Ariel Kelly ’2022 Lainey Lavelle ’22 Faculty Mentor: Professor Faculty Mentor: Professor Mihai Faculty Mentor: Professor Lara Dick, Ellen Chamberlin, GEOLOGY & Banciu, ANALYTICS & OPERATIONS MATHEMATICS ENVIRONMENTAL GEOSCIENCES MANAGEMENT Funding Source: James L.D. and Funding Source: Kalman Fund for Funding Source: Program for Rebecca Roser Research Fund Undergraduate Research in the Sciences Undergraduate Research A Study of Teacherpreneurs Evaluating the Impact Does Global Trade Help or Who Create Elementary of Stream Restoration Techniques on Bank Erosion, Hinder Economic Inequality? Mathematics Stream Morphology, and Curricular Resources Soil Carbon at an Unnamed Taiba Khan ’22 Tributary of Pine Creek Faculty Mentor: Professor Benowitz- Camillo Lazarczyk and Simon Behr ’21 near Woodward, central Fredericks, BIOLOGY Faculty Mentor: Professor Vivienne Pennsylvania Wildes, MANAGEMENT Funding Source: Department of Biology Funding Source: Senior Design and Relationship between Jeffrey Heim ’21 Research Sponsorship; Conducted within aggression, body condition, Faculty Mentor: Professor Christopher a class for the College of Management and parental feeding in Martine, BIOLOGY using Qualtrics and with the support chicks of the seabird species Funding Source: Department of Biology; of Vivienne Wildes of the College of Black-legged kittiwakes (Rissa Program for Undergraduate Research Management, and Agnes Jasinska of tridactyla) A Population Genomics Bertrand Library’s Research Help Approach to Understanding Shane Kozick ’23 Reducing Food Waste In the Role of Indigenous Faculty Mentor: Dr. Vanessa Troiani, The Restaurant Industry Foragers in the Distribution (ADMI lab director), NEUROSCIENCE and Genetic Diversity of an Funding Source: Summer Autism Jaden Lee ’22 Australian Wild Bush Tomato and Neurodevelopmental Disorders Faculty Mentor: Professor Benjamin (Solanum diversflorum) Internship (SANDI) Wheatley, MECHANICAL ENGINEERING Measuring Concordance of Funding Source: John P and Mary Jane Cameron Hong ’21 Subtype Sulcogyral Patterns Swanson Professorship in Engineering Faculty Mentor: Professor Kenneth in Monozygotic and Dizygotic & the Sciences Mineart, CHEMICAL ENGINEERING Twin Pairs Using Finite Element Funding Source: National Science Klaudia Kulawska ’21 Modeling to Investigate the Foundation Grant (NSF) Effect of Mechanical Loading Assessing Solvent Viscosity Faculty Mentor: Professor Judith Grisel, on Muscle Extracellular Impact on the Physical PSYCHOLOGY Matrix Microstructure Characteristics of Polymeric Funding Source: N/A Organogels The Implications of Kaelyn Long ’21 Socioeconomic Status on Faculty Mentor: Professor Lara Dick, April Hurlock ’23 Maternal Language Input and EDUCATION; MATHEMATICS Faculty Mentor: Professor Douglas Child Language Outcomes Funding Source: Research was for Collins, CHEMISTRY course credit Funding Source: STEM Scholars; Alfred Wutt Hmone Thin Kyi ’22 My Experiences Re-immersing P. Sloan Foundation - Chemistry of Faculty Mentor: Professor Karlo into “Introduction to Indoor Environments Malaga, BIOMEDICAL ENGINEERING Mathematical Thought” Effect of Self-Oxidation on Funding Source: Program for Deposited Cigarette Smoke Undergraduate Research 2020 Catherine MacKay and Composition and Third-Hand Effect of White Matter Brooke Echnat ’21 Smoke Stimulation on Clinical Faculty Mentor: Professor Anjalee Outcomes in Thalamic Hutchinson; Professor Bryan Valerie Justice ’21 Deep Brain Stimulation for Vandevender, THEATRE & DANCE Faculty Mentor: Professor Christopher Essential Tremor Funding Source: Bucknell Department Daniel, GEOLOGY & ENVIRONMENTAL of Theatre and Dance GEOSCIENCES The Show Must Go On! Funding Source: Department of Geology & Environmental Geosciences U-Pb Isotope Dating of Monazite in the Sierra Estrella Mountains of Arizona: Evidence for ca. 1.4 Ga Metamorphism and Deformation 4 KA LMA N RESEAR C H S Y M PO S I UM
Margaret Anne MacNeille ’21 Nicholas Passantino ’21 Ben Travis ’22 Faculty Mentor: Professor Lara Dick, Faculty Mentor: Professor Joshua Faculty Mentor: Professor Mark MATHEMATICS Stough, COMPUTER SCIENCE Haussmann; Dr. James Greenberg, Funding Source: Helen E. Royer Funding Source: Presidential Fellowship BIOLOGY; Chief of Gynecology, Brigham Undergraduate Research Fund Domain Adaptation in Machine and Women’s Faulkner Hospital - Associate What’s Out There? Learning for Medical Imaging Professor, Harvard Medical School Investigating Online Teacher Funding Source: Bucknell Public Interest Created Activities Lucas Rankin, Graduate Student Program Fund Faculty Mentor: Professor Kenneth A Comparison of Estimated Claire Marino ’23 Mineart, CHEMICAL ENGINEERING and Quantitative Blood Loss in Faculty Mentors: Professor Christopher Funding Source: National Science Childbirth, and Investigation Martine; Dr. Tanisha Williams, BIOLOGY Foundation Grant (NSF) of Risk Factors for Postpartum Funding Source: David Burpee Establishing the Independent Hemorrhages Endowment; Department of Biology Tunability of the Mechanical Solanum “Deaf Adder” a New and Transport Properties of Emily Tully ’21 Bush Tomato Species from the Polymer Gels Faculty Mentor: Professor Benjamin Australian Monsoon Tropics Wheatley, MECHANICAL ENGINEERING Coco Sachs ’21 and Lily Shorney ’22 Funding Source: Engineering Data Thomas Matsumura ’22 Faculty Mentor: Professor Chris Generation Grant Faculty Mentor: Professor Benjamin Boyatzis, PSYCHOLOGY Location Dependent Wheatley, MECHANICAL ENGINEERING Funding Source: N/A Mechanical Behavior of Funding Source: Bucknell-Geisinger The Psychological Impact of Aponeurosis Tissue Under Research Initiative COVID-19 and Social Distancing Uniaxial Tensile Stretch Measuring Lower Limb Muscle Activity and Kinematics in Jake Schaefer ’24 Anurag Vaidya ’21 Variable Foot Strike Gaits Faculty Mentor: Professor Benjamin Faculty Mentor: Professor Joshua Wheatley, MECHANICAL ENGINEERING Stough; Professor Benjamin Wheatley, John Mirsky ’23 Funding Source: John P and Mary Jane COMPUTER SCIENCE; MECHANICAL Faculty Mentor: Professor David Rojas, Swanson Professorship in Engineering & ENGINEERING LATIN AMERICAN STUDIES; SOCIOLOGY & the Sciences Funding Source: Presidential ANTHROPOLOGY The Mechanical Properties of Fellowship Funding Source: Douglas K. Ramming Animal Horn Shapes Perceptually Improved Candland Undergraduate Research Medical Image Translations Fund;Presidential Fellowship Bryan Scutari ’23 Using Conditional Generative Housing Illness in a PA Faculty Mentor: Professor Tom Adversarial Networks Mushroom Town Geurts, ACCOUNTING & FINANCIAL MANAGEMENT Ruoying Zhang ’21 Philip Onffroy ’22 Funding Source: IMA Research Faculty Mentor: Professor Jasmine Faculty Mentor: Professor Katsuyuki Foundation Mena, PSYCHOLOGY Wakabayashi, CHEMICAL ENGINEERING The Financial Impact of an Funding Source: Program for Funding Source: College of Engineering; ISO14001 Certification Undergraduate Research Presidential Fellowship Chinese International Students Ray’cycle Initiative: Julia Tokish ’22 in the US: The Influence of Characterizing Faculty Mentor: Professor Meenakshi Discrimination, Acculturation and Productizing Community- Ponnuswami, ENGLISH and Coping on Psychological Sourced Funding Source: Presidential Fellowship Wellbeing Plastic Waste Uncovering South Asian- Diamanda Zizis ’23 Anthony Orlando ’24 American Playwrights Faculty Mentor: Professor Christopher Faculty Mentor: Professor Kenneth Martine, BIOLOGY Tung Tran ’23 Mineart, CHEMICAL ENGINEERING Funding Source: David Burpee Faculty Mentor: Professor Joshua Funding Source: Presidential Fellowship Endowment;Presidential Fellowship Stough, COMPUTER SCIENCE Mechanical Testing of Wax- What Happens When you Cross Funding Source: HTIP based Polymer Gels Plant Species with Two Distinct Bayesian Optimization for 2D Echocardiography Sexual Systems?: An Ex Situ Segmentation Hybridization Approach BU C K N E L L U N I VE R SIT Y 5
Akil Atkins ’22 Emily Brandes ’21 Faculty Mentor: Professor Christopher Dancy, Faculty Mentor: Professor Scott Meinke, POLITICAL COMPUTER SCIENCE SCIENCE Funding Source: National Science Foundation Grant (NSF) Funding Source: Honors Thesis in Political Science Catch The Pig! Understanding the To Believe or Not to Believe: A Closer Look Interaction Between People and AI at the Impact of Sexual Assault in Politics Our study sought to investigate the ways in which Since the viral 2017 #MeToo movement, public people would interact with an AI Agent, based on opinion on cases of sexual misconduct have been how the agent was racialized. To investigate this shaped by the mainstream media coverage of high we modeled a game after the stag hunt task, where profile stories. A changed culture has allowed more participants were tasked with gaining as many points victims to come forward and share their stories, many as possible. Participants could gain points by either detailing harrowing events perpetrated by successful cooperating with an AI agent to capture a pink game businessmen and politicians. Credible accusations piece, which represented a pig or exiting the game continue to come forward, and while some end in legal through the black squares on either side of the board. action, many do not, and perpetrators face little to no The study was a true experiment in which participants consequences. I examined how individuals respond were randomly assigned to one of three conditions. to issues of sexual misconduct and assault in politics, Participants were either assigned to a condition and based on the severity of the accusation, how they where the AI was racialized as Black, where the AI respond. Through my survey data research, I was able was racialized as white, or a condition where the AI to isolate responses to see the influence that party wasn’t racialized at all, which represented the control affiliation and gender have on individuals opinion condition. After completing the game participants formation. The research reflects a consistent partisan were asked three survey questions to assess how they difference between Republicans and Democrats in perceived the AI’s strategy when playing the game. terms of reaction, with Democrats consistently being in So far our results have shown that participants in the favor of harsher consequences, both when Democratic, control condition were more likely to believe the AI was and Republican perpetrators are involved. These working with them to capture the pig than participants responses indicate a strong partisan bias in individuals, in both the Black and white treatment groups. and additionally I found that when a history of sexual Moreover, the participants in the white treatment misconduct was present, individuals also reacted more group were more likely than those in the Black harshly as opposed to politicians with no history. treatment group to believe the AI agent was working them to capture the pig. The results do suggest that there is a relationship between the racialization of AI Ryan Bremer ’22 and how people interact with AI Agents. Faculty Mentor: Professor Ken Eisenstein, English - Film/Media Studies Funding Source: Dalal Innovation and Creativity Grant Genevieve Block ’22 for Student-Faculty Collaboration Faculty Mentor: Professor Shaunna Barnhart, GEOGRAPHY Brakhage’s Adjacents Funding Source: American Association of Geographers The goal of Brakhage’s Adjacents is to better understand the working methods and aesthetic Homelessness Awareness and Response decision making of the avant-garde filmmaker Stan in Shamokin, PA Brakhage (1933-2003). By focusing upon his use of This semester, I am participating in a research montage (the complex way in which he combined internship studying homelessness in Shamokin, PA. I shots in his non-narrative and almost entirely silent am working to understand the rise of homelessness 16mm films), we learn more about Brakhage’s editing in the area and the resources that need to be created habits as well as the messaging behind these very to support this population. The research internship challenging films. This is done by viewing splice- will culminate in a list of suggestions to the local PA adjacent frames on an actual film strip, showing government with ideas to support homeless people the literal cuts that were made when the films were and help to alleviate poverty. produced decades ago. Brakhage’s Adjacents draws from wider histories of narrative filmic editing [notably the advanced montage ideas of Sergei Eisenstein (1898-1948)] while adapting these notions to the under-realized realm of avant-garde cinema. 6 KA LMA N RESEAR C H S Y M PO S I UM
Ella Carlander ‘22 and Michael Bolish ‘23 only for left ventricle endocardium, this effort extends Faculty Mentor: Professor Katharina Vollmayr-Lee, at little cost generalizable, multi-structure video PHYSICS & ASTRONOMY segmentation to a large clinical dataset. Funding Source: National Science Foundation Grant (NSF) Computer Simulations of Granular Media Weiru Chen ’21 We will summarize the research we conducted under Faculty Mentor: Professor Hava Turkakin, PHYSICS & Katharina Vollmayr-Lee this past summer in the ASTRONOMY field of Granular Media. We built, ran, and analyzed Funding Source: Undergraduate Research Advisory Council molecular-dynamics simulations that modeled the Investigations of Kelvin-Helmholtz behavior of this compelling type of material. Our talk Instability (KHI) and Associated will give a brief definition of Granular Media, explain Magnetosonic Wave Emission in the Solar the tools we used to build our simulations, display Corona: New Impacts on Coronal Heating some results, and justify why research in this field is Previous studies have observed that Kelvin-Helmholtz relevant and important. Instability (KHI) and Magnetohydrodynamics (MHD) wave emissions along various shear flow boundaries in Solar-Terrestrial environment may transport Edward Chen ’22 energy between different regions of the sun. We Faculty Mentor: Professor Joshua Stough, COMPUTER expand upon these previous studies to investigate SCIENCE the nonlinear evolution of KHI and MHD waves along Funding Source: Ciffolillo Healthcare Technology the boundaries of coronal mass ejections (CMEs), Inventors Program large eruptions of the corona that have a significant effect on satellites, earth’s power grids, and humans Assessing the Generalizability of in space. We measure the strength of KHI growth and Temporally Coherent Echocardiography MHD wave emission, and the efficiency of energy Video Segmentation transportation by these MHD waves using 2-D/3-D Existing deep-learning methods achieve state-of-art magnetohydrodynamic modeling software in order segmentation of multiple heart substructures from to first, identify KHI growth, and second, calculate the 2D echocardiography videos, an important step in the strength of the energy that these waves transport diagnosis and management of cardiovascular disease. to the solar corona. The code we use is component- However, these methods generally perform frame- based parallel computer code written in Fortran90 and level segmentation, ignoring the temporal coherence C programming languages. Our preliminary results in heart motion between frames, which is a useful demonstrate KHI and wave emission development signal in clinical protocols. In this work, we implement along the boundary over time, showing that in real temporally consistent video segmentation, which life conditions along the CME boundary, KHI and MHD has recently been shown to improve performance emission is possible. on the multi-structure annotated CAMUS dataset. We show that data augmentation further improves results, which are consistent with prior state-of-art Ian Coates ’21 works. Our 10-fold cross-validation shows that video Faculty Mentor: Professor Kenneth Mineart, segmentation improves the automatic comparison to CHEMICAL ENGINEERING clinical indices including smaller mean absolute errors Funding Source: College of Engineering; National Science for left ventricular end-diastolic volume (8.7 mL vs Foundation Grant (NSF) 9.9 mL), end-systolic volume (6.3 mL vs 6.6 mL), and ejection fraction (EF) (4.6% vs 5.3%). In segmenting key Assessing the Impact of Block-Selective cardiac structures, video segmentation achieves mean Homopolymers on the Diffusion of Dice overlap of 0.93 on left ventricular endocardium, Payload Through Polymeric Organogels 0.95 on left ventricular epicardium, and 0.88 on The goal of this project is to investigate the impact of left atrium. To assess clinical generalizability, we a gel-miscible polymer additive on gel nanostructure, further apply the CAMUS-trained video segmentation gel mechanical behavior, and sodium bis(2-ethylhexyl) models, without tuning, to a larger, recently published sulfosuccinate (AOT) release rate. Characterizing gels’ EchoNet-Dynamic clinical dataset. On 1274 patients in mechanical behavior and release of AOT through these the test set, we obtain absolute errors of 6:3% ± 5:4 in gels will benefit future applications like transdermal EF, confirming the reliability of this scheme. In that the drug delivery through informed structure-property EchoNet-Dynamic videos contain limited annotation (i.e., nanostructure-diffusion) relationships. Previous work in our group has shown that gel nanostructure BU C K N E L L U N I VE R SIT Y 7
is tuned by varying the amount of gel-forming SEBS copolymer. The purpose of this project is to further Previously reported zircon ages for the area suggest investigate methods of gel nanostructure tuning by partial melting near 1.4 Ga (Meijer, 2019). The identifying the impact of a discrete phase-selective timing and P-T conditions of metamorphism in the polymer on organogel properties. Specifically, the Sierra Estrella mountains are similar to high-grade impact of additive polymer concentration of gel metamorphic rocks in northern New Mexico and nanostructure, mechanical response, and diffusivity southern Colorado; these rocks likely represent the will be studied. The current work uses Fourier- southwestern extension of the Picuris orogenic belt transform infrared spectroscopy (FTIR) to track changes in gel AOT concentration over time for gels with ranging homopolymer concentrations. The Jacob Feuerstein ’22 acquired data is modeled using Fick’s laws to yield Faculty Mentor: N/A a diffusion coefficient for each gel formulation. We Funding Source: N/A hypothesize that the aforementioned nanostructure trends are the culprit for our observation that The Choppy Purple Surf: Understanding diffusion of AOT decreases with increasing polystyrene the 2020 Election in Rural Pennsylvania additive polymer concentration. Understanding these The 2020 election was a point of inflection for relationships will provide key insight for biomedical Democratic candidates across the United States. and agricultural payload delivery applications. Securing tossup states like Pennsylvania and Arizona along with parts of the industrial Midwest, the performance of Joe Biden and other down ballot Julian Cohen ’21 candidates raises serious questions about the future Faculty Mentor: Professor Christopher Daniel, of the Democratic Party. In particular, the geographic GEOLOGY & ENVIRONMENTAL GEOSCIENCES distribution of voters in the 2020 election surprised Funding Source: Program for Undergraduate Research many in election-watching circles. Determining the Metamorphic Conditions While many have analyzed Biden’s over-performance of ca 1.4 Ga Rocks from the Sierra Estrella in suburbia and underperformance with Hispanics Mountains, Arizona USA: An Application of in Texas and Florida, few have attempted to break Raman Thermobarometry down the results of the election in rural Pennsylvania. Meijer (2019) reported what is likely the first known Because it is at such a unique intersection of the class, occurrence of Mesoproterozoic granulite facies rocks race, and conservative-liberal divide, understanding in Arizona. However, the temperatures and pressures the rural election results is crucial to developing of metamorphism are unknown. To better constrain strategies for improving Democratic performance in the conditions of metamorphism, metapelitic rocks the Midwest and South. were collected from the north end of the Sierra Estrella mountain range and are characterized by As the Campaign Manager for a Democrat in 85th Grt-Bt-Pl-Qtz-Ky-Sil with significant retrograde Ms- District of Pennsylvania (Lewisburg, Selinsgrove, Chl-Ep, and Grt-Bt-Pl-Qtz-Ky-Sil-Kfs with very little Mifflinburg), I had the opportunity to interact with retrograde overprint. Preliminary thermodynamic thousands of voters and develop strategies to improve modeling of these two samples was performed with outcomes in a R +32 district. The statewide data tells Theriak- Domino and the H&P-98 data set. The Sil us that the 2020 election in Pennsylvania was, as inclusions within Grt suggest Sil growth possibly local organizer Jordi Comas coined, an example of the during subsolidus St-breakdown or Ms-melting in “choppy purple surf.” In other words, the Republican both samples. The presence of Ky bearing melt turnout was unusually large, but slightly over-crested textures in both samples may reflect prograde growth by Democratic voter turnout. of Ky from Ms- or Bt-melting suggesting minimum PT conditions > 7.5 kbar and > 700 °C. A significant I will review the results of the election for my campaign amount of retrograde Ms in sample implies in-situ in both a historical and geographical context and melt crystallization during retrograde cooling. answer the question, “How did the ‘choppy purple surf’ To further constrain pressures of metamorphism, play out in the the 85th District and other parts of rural Raman spectroscopy was employed to measure peak Pennsylvania?” positions of quartz inclusions in garnet (QuiG). The results of this work show peak shifts ranging from 0 to -0.1 cm-1. This equates to metamorphic pressures of 8-9 kbar at about 750-800 °C. 8 KA LMA N RESEAR C H S Y M PO S I UM
Michael Duncan ’23 tendon and muscle fibers interact with one another Faculty Mentor: Professor Douglas Collins, CHEMISTRY in the transition zone. It has been observed that there Funding Source: Presidential Fellowship is a non-uniform strain placed on the aponeurosis, and so imaging of the tissue will reveal how force Gas-Phase Chemical Ionization Orbitrap affects the alignment of the collagen fibers found Mass Spectrometry in aponeurosis tissue. Examining how the waviness The most common method of analysis for trace gases of collagen fibers changes as the tissue is placed in air employs chemical ionization time of flight mass under force will allow for better understanding of the spectrometry (CI-TOF-MS). Transportable CI-TOF- material and structural properties of aponeurosis MS instruments have relatively low mass resolving tissue. Evaluating these characteristics will help us power (m/Δm < 10,000), meaning it is difficult to better understand how damages to the tissues occur, distinguish molecules with the same integer mass, how those damages can be repaired and rehabilitated, but with different elemental composition. Orbitrap and how to properly develop computer models of the mass spectrometry, however, can routinely achieve musculoskeletal system. Sample images using the SEM resolving powers > 50,000, allowing for the exact have been taken to develop a general understanding monoisotopic mass to be determined. However, of aponeurosis morphology. Orbitrap instruments are most commonly designed to analyze sprayed liquid samples. Atmospheric chemists commonly need to analyze the molecular Gari Eberly ’21 Faculty Mentor: Professor Katherine Hays, ENGLISH; composition of gases that include a variety of large CREATIVE WRITING organic molecules that have similar mass to charge Funding Source: N/A ratios as one another, making it difficult to accurately identify them using a CI-TOF-MS. This project set out to design an chemical ionization apparatus for Synthesis Synthesis is a collection of poetry that explores how Orbitrap mass spectrometry and allow for the analysis gender relations and race amalgamate to impact of gaseous samples. The design has been focused the maturation of an individual. These poems are around low costs, modularity, and adaptability, all in scientifically-aware and influenced by my concurrent order to keep the horizon of users and use cases as education in both Creative Writing and Biomedical broad as possible. Analyte ions will be formed by ion- Engineering. For the past four years, I have sought molecule reactions within a cone-shaped flow reactor. to bridge the gap between my two academic Reagent ions will be supplied to the ion-molecule commitments: poetry and science. Both poetry and reactor using a continuous soft x-ray photoionization science exist as a means to ask and answer questions process. Computer-aided design in Solidworks along about the messy interactions that shape personalities with rapid prototyping with 3D-printing has allowed and relations with the broader world. To be successful, for conceptualization, realization, and testing of key both tools require dedication to detail, creativity, and components before fabrication. The first machined exploration. On the page, poets mold language to reveal prototype is the next major step which will provide the startling truths about how we engage with the world. opportunity to test the concept. In a lab, engineers leverage scientific theories to build technological innovations. Despite these similarities, Olivia Dyer ’22 I have noticed that interactions between poetry and Faculty Mentor: Professor Benjamin Wheatley, science remain faint: a missed connection at the train MECHANICAL ENGINEERING station, an asymptote that never opens its mouth. Funding Source: The John P. & Mary Jane Swanson Through this collection, I instead seek to converge these Professorship in Engineering & the Sciences two disciplines at a single point by melding personal experience with scientific observations, as explored Visual and Mechanical Characterization of through a variety of poetic forms. the Muscle to Aponeurosis Junction Aponeurosis is a tendinous sheath-like tissue found in many muscle-tendon units, and the muscle- aponeurosis junction is poorly understood. We want to determine the structure of the transition from muscle to aponeurosis and how it may be similar or different from the myotendinous junction. Imaging and visually characterizing the muscle-aponeurosis junction using SEM imaging of tissue samples will show how the BU C K N E L L U N I VE R SIT Y 9
Caroline Eckert ’21, Amber Coleman ’21, Alexis swimmer aggregation in low-shear regions of the flow Faria ’22, Clara Han ’21, Makenna Luzenski ’23, to aggregation in high-shear regions as the parameters Lauren Shearer ’22 and Grace Wilder ’21 are varied. We find that rotational diffusion tends to Faculty Mentor: Professor Chris Boyatzis, drive swimmers into certain parts of phase space. PSYCHOLOGY We characterize the dependence of this noise-driven Funding Source: Program for Undergraduate Research phase-space aggregation on a swimmer’s speed, aspect ratio, and rotational diffusivity. The properties Native Danish Mother’s Intersection of the swimmer trajectories with noise explain the Between Parenting Approach and Religion transition from high-shear to low-shear aggregation. (KS This study investigated Danish mothers’ beliefs about Ferguson, SA Berman, KA Mitchell, TS Solomon, 2020) parenting and the role of religion in family practices and discussions. Denmark is famous as one of the most secular nations in the world (Zuckerman, 2008), Mackenzie Flynn and Bree McCullough ’22 yet religion is, perhaps surprisingly, a component of Faculty Mentor: Professor Ben Hayes, WATERSHED family discussion, especially about death and morality SCIENCES AND ENGINEERING PROGRAM (Zajac & Boyatzis, 2020). In this study, 15 native Funding Source: United States Forest Service Danish mothers, all fluent in English with at least one child between ages of 4 and 14, were interviewed Little Arnot Run: An Evaluation of about mothers’ religious beliefs and how they were Groundwater-Surface Water Interactions incorporated into family discourse and practices, with Regard to Hyporheic Exchange and especially on issues of morality, religious holidays, Temperature death, and the afterlife. Transcripts are being coded Little Arnot Run is a second-order stream in the by a team creating a coding system using inductive Allegheny National Forest, Pennsylvania that has and deductive thematic analysis. Team members been historically altered by logging and oil and individually analyzed transcripts and then met to natural gas wells. In many areas, the stream was work toward a shared coding system for interpreting dredged, straightened, and converted to a narrow, themes in the mothers’ views. Coding is in progress, deep, single-thread channel, which continues to be with these preliminary themes: mothers’ respect disconnected from the floodplain. This project is part for children’s autonomous beliefs (i.e., reluctance to of a larger stream restoration study by the United impose their own beliefs), promotion of the child’s States Forest Service (USFS) and Bucknell University character, tolerance for diverse religions (and mothers’ currently underway working to characterize the factors lack of strong commitment to any one faith), mothers’ controlling geomorphic processes operating within the ongoing reflection and growth, and concern for watershed in order to direct restoration activities set children’s age-appropriate exposure. Preliminary to take place later in the year. Our preliminary analysis analyses suggest Danish mothers have a distinctive of groundwater piezometers, stream temperature orientation to the role of religion in the family, one gauge station data, and weather station data suggests quite disparate from most American families (Boyatzis significant hyporheic exchange to the channel. We are et al., 2015). currently assessing both shallow and alluvial aquifers as well as in deeper sections of the stream in order to quantify groundwater-surface water exchange and Kyle Ferguson ’21 potential for reconnecting abandoned side channels Faculty Mentor: Professor Thomas Solomon, PHYSICS and vernal pools on the floodplain. We will be using & ASTRONOMY precipitation to look at the rate and direction of the Funding Source: NSF Grant DMR-1806355, NSF Grant hydrostatic driven hyporheic exchange caused, in part, CMMI-1825379 by changes in the ground and surface water elevation and analyzing variations in temperature throughout Noise-Driven Aggregation of Swimmers in the system. the Kolmogorov Flow We investigate theoretically the dynamics of ellipsoidal microswimmers in an externally imposed, laminar Kolmogorov flow. Through a phase-space analysis of the dynamics without noise, we find that swimmers favor either cross-stream or rotational drift, depending on their swimming speed and aspect ratio. When including noise, i.e. rotational diffusion, Langevin simulations of our model show a transition from 10 KALMAN RE S EA R C H S Y M PO S I UM
Maya Freeman ’23 prevent further deformity during adolescence. The Faculty Mentor: Professor Cecilia Bove, BIOLOGY topic of screw removal is quite controversial. If the Funding Source: Department of Biology screws are left in the patient, there is the potential that fractures may occur later in life due to stress risers, yet Fluoroquinolone-based Therapy and screw removal requires a second surgical operation. In Onset of Functional Gastrointestinal addition, there is no standard screw that is used for the Disorders in Human Subjects procedure. Different physicians prefer various types of Fluoroquinolones (FQs) are a broad class of antibiotics screws including titanium vs. non-titanium, cannulated typically prescribed for several infectious diseases, vs. non-cannulated and threaded vs. partially-threaded. including common infections for which the use of FQs Therefore, the purpose of this research project is to is discouraged. Indeed, the FDA has proposed the determine the amount of torque required to remove existence of a permanent disability (Fluoroquinolone various types of orthopaedic screws after closure of the Associated Disability; FQAD), which, despite being physis. This analysis will quantify how various screws fairly common after FQs use, has yet to be formally perform during screw removal and provide insight into recognized by healthcare professionals worldwide. tissue damage that may occur due to screw removal. Previous studies suggest that FQs act as selective The ultimate goal of this study is to determine the inhibitors of GABAA receptors, preventing the binding optimal screw to use during the procedure that will of the inhibitory neurotransmitter GABA in the central cause the least amount of damage after bone growth nervous system. GABA is a key regulator of the neural has occurred around the screw. circuit regulating gastrointestinal function. In order to assess whether there is a correlation between the use of FQs and the onset of functional gastrointestinal (GI) Emily Haas ’21 disorders, a questionnaire was sent to 367 individuals Faculty Mentor: Professor Ellen Chamberlin, GEOLOGY who were prescribed FQs addressing their gut health & ENVIRONMENTAL GEOSCIENCES in the last year. Survey participants were divided Funding Source: Kalman Fund for Undergraduate into three groups based on the type of FQ they were Research in the Sciences prescribed. Chi-square analysis revealed that while all participants had a significant degree of functional GI Evaluating the Impact of Stream disorder, certain FQs are associated with more severe Restoration Techniques on Bank Erosion, and more frequent gastric pain, difficulty producing Stream Morphology, and Soil Carbon at a bowel movement and harder stools. Lastly, a an Unnamed Tributary of Pine Creek near significant portion of respondents also reported Woodward, central Pennsylvania frequent swelling or bloating. In conclusion, these Live staking is a stream restoration technique in data indicated that permanent functional GI disorders which live cuttings and stems taken from native may present after FQs administration, and that certain species of trees and shrubs are placed into stream FQs produce more severe symptoms than others. Our banks, eventually growing into new plants which aids study highlights the need to revisit current guidelines in riverbank protection by increasing soil cohesion. for the administration of FQs for individuals already Because of the growing use of live staking in stream potentially at risk to develop functional GI disorders. restorations, there is a growing need for research on the link between live staking and geomorphic resiliency. Here we investigate the impact of live staking on bank erosion, stream morphology, and soil Keith Grega ’21 carbon (SC) at an unnamed tributary of Pine Creek Faculty Mentor: Professor Benjamin Wheatley, near Woodward, Pennsylvania. MECHANICAL ENGINEERING Funding Source: Bucknell-Geisinger Research Initiative In this study, we collected baseline data for a long- term study of the impact of live stakes on the Impact of Screw Type on Torque During floodplain and channel geomorphology, and we SCFE Screw Removal investigated the baseline SC distribution. Preliminary Slipped Capital Femoral Epiphysis (SCFE) is a disorder results from stream channel surveying indicate that occurs in adolescents in which the femoral head undercut banks, channelization, very low stream slips with respect to the femoral neck. SCFE can lead velocity, and silt and clay on the stream bed. to abnormal hip mechanics which may result in the Throughout the field site, the soils are silty loams need for realignment of the femoral head through with thin O-horizons and some local variability within surgery. Percutaneous in situ fixation is the most transects. SC analysis shows carbon values between common treatment for SCFE, where the femoral head 0.36% and 3.32%, which is low for the expected is realigned on the neck through screw insertion to BU C K N E L L U N IVE R SIT Y 11
range of SC for degraded floodplain soils in this Cameron Hong ’21 environment. We predict that in future years, as the Faculty Mentor: Professor Kenneth Mineart, live stakes vegetate the stream banks at this site, there CHEMICAL ENGINEERING will be an increase in soil carbon, changes in stream Funding Source: National Science Foundation Grant (NSF) bed character and channel sinuosity, and more soil variability. Assessing Solvent Viscosity Impact on the Physical Characteristics of Polymeric Organogels Jeffrey Heim ’21 Traditionally, studies of polymeric organogels focus on Faculty Mentor: Professor Christopher Martine, the impact of polymer factors on the gels’ mechanical BIOLOGY and transport properties. Alternatively, this study Funding Source: Department of Biology; Program for seeks to assess the impact of altering solvent viscosity, Undergraduate Research while holding polymer factors constant. The gels in this study were composed of styrene-ethylene- A Population Genomics Approach to butylene-styrene (SEBS) triblock copolymer, oleic acid Understanding the Role of Indigenous (OA), and mineral oil. Samples were formulated at Foragers in the Distribution and Genetic 10, 20, and 30 wt% SEBS copolymer for each mineral Diversity of an Australian Wild Bush oil, varying in viscosity from ~30 mPa*s to ~500 Tomato (Solanum diversflorum) mPa*s. Uniaxial mechanical testing was performed to The Indigenous foragers of Australia’s Western Desert, determine Gc, the contributions of physical crosslinks, known as the Martu people, have a rich and deep i.e., micelles, to stress, and Ge, the contributions of connection to the landscape that is evident through chain entanglements to stress. Modeling the data their culturally significant pathways of movement. from these experiments showed that Gc and Ge only In creating this connection, we wonder how these varied with polymer concentration. In a separate set of pathways have shaped the distribution, abundance, experiments, Fourier Transform Infrared Spectroscopy and dispersal of wild plants, specifically the (FTIR) was used to track the diffusion of OA out of economically significant bush tomatoes of the genus the gel. Through modeling the release of OA with Solanum (including Solanum diversiflorum, known time using a Fickian diffusion model, the diffusion locally as wamula). Currently, herbarium and field coefficients for formulations at varying solvent collected specimens have been sampled from across viscosities were determined. Notably, the results of the the range of Solanum diversiflorum. These samples FTIR experiments conform to behavior predicted by are being used to understand genetic connectivity, the Stokes-Einstein equation. The results from these as well as the potential impact of Indigenous users two sets of experiments allows for a higher degree of on S. diversiflorum’s population structure. DNA has tunability than previously available. The results from been extracted from each specimen using FastDNA this study will be of particular use in development of kits and stored for future quality testing. We expect transdermal drug delivery devices. to find a correlation between the movement of the Indigenous people and the dispersal of the species along pathways of movement, as well as patterns Valerie Justice ’21 that align with the historical distributions of language Faculty Mentor: Professor Christopher Daniel, groups. This would imply that the activities of the GEOLOGY & ENVIRONMENTAL GEOSCIENCES Indigenous people profoundly shaped the distribution Funding Source: Department of Geology & of the species and can give conservationists as well Environmental Geosciences as anthropologists new insights on the relationship between the biogeography of plants in the Western U-Pb Isotope Dating of Monazite in the Desert and the people who have lived there for Sierra Estrella Mountains of Arizona: thousands of years. Evidence for ca. 1.4 Ga Metamorphism and Deformation U-Pb isotope dating of monazite from the Sierra Estrella mountains near Phoenix, Arizona, yield metamorphic ages between about 1.42 and 1.40 billion years ago (b.y.a). The timing is important to determine if the metamorphic rocks formed as part of the ca. 1.45 billion year old (b.y.o.) Picuris Orogeny. Multiple samples were collected from the Sierra Estrella mountains. Four of these samples were selected for 12 KALMAN RE S EA R C H S Y M PO S I UM
monazite U-Pb analyses. Laser Ablation-Inductively Taiba Khan ’22 Coupled Plasma-Mass Spectrometry (LA-ICP-MS) was Faculty Mentor: Professor Benowitz-Fredericks, used to measure U-Pb isotope ratios, which was done BIOLOGY in a lab at the University of New Brunswick. The four Funding Source: Department of Biology samples are named CD20-14b, CD20-09, CD20-07Bb, and CD20-03Ba. Concordia plots for CD20-14b yield Relationship between aggression, body ages of monazite growth of 1420 +/- 6 Ma (MSWD condition, and parental feeding in chicks = 0.18). Concordia plots for CD20-09 yield ages of of the seabird species Black-legged 1410 +/- 10 Ma (MSWD = 0.74). Concordia plots for kittiwakes (Rissa tridactyla) CD20-07Bb yield ages of 1410 +/- 4 Ma (MSWD = Black-legged kittiwakes, Rissa tridactyla, are small 0.25). Concordia plots for CD20-03Ba yield ages of gulls that exhibit biparental care and typically brood 1400 +/- 5 Ma (MSWD = 0.13). All measured ages are 1-2 chicks. First hatched chicks (A chicks) commonly near concordant, with MSWD values demonstrating display aggressive behavior towards the second degree of concordance. Samples CD20-03Ba and hatched chicks (B chicks), sometimes resulting in CD20-07Bb are located in the northern part, and CD20- the death of the B chick. Food availability may be a 09 and CD20-14b are located in the southern part. driving factor of chick aggression but questions remain Metamorphism youngs northward with ages spanning regarding the relationships among chick behavior, about 20 million years across the range from north to growth and parental feeding. In this study, we test south. Our measured U-Pb ages are similar to 1424- three competing hypotheses: H1) Stronger chicks 1409 Ma ages previously reported in the northern Taos display more aggressive behavior to monopolize more Range in New Mexico, which suggests formation during food. H2) Weaker chicks display more aggressive the same Picuris orogenic event (1450-1400 Ma). behavior because they need to obtain more food. H3) There is no relationship between aggressive behavior and body condition. To test these hypotheses, we Ariel Kelly ’2022 used video footage to observe the behavior of 29 Faculty Mentor: Professor Mihai Banciu, ANALYTICS & five day old A chicks. At half of the nests (fed nests), OPERATIONS MANAGEMENT parents were provided with supplemental fish, while Funding Source: Program for Undergraduate Research the remaining half (unfed nests) had to rely on natural means of foraging. ‘A’ chick aggression towards the Does Global Trade Help or Hinder B chick was categorized by pecking and squeezing or Economic Inequality? twisting of the neck; an attack series with pauses of The issue of globalization and its perceived winners less than five seconds counted as one demonstration and losers has recently come to the forefront of of aggression. If H1 is true, we will see a positive international conversation. In this project, we seek correlation between aggression and body condition, to answer the following question: has global trade and higher aggression rates in the fed group (chicks helped decrease economic inequality? To address with more food availability). If H2 is true, there will be this problem, we created a tool that could be used to a negative correlation between aggression and body quantify the effect of global trade over time. Using a condition, and higher aggression rates in chicks in graph-theoretical approach, we adapt the Page Rank the unfed group (chicks that are not provided with algorithm to account for a country’s importance in supplemental food). the trade network when considering financial flows that go in both directions, that is, both exports and imports. We then use the relative importance scores to quantify the economic inequality by computing the Shane Kozick ’23 Gini coefficient of the world’s economy, as well as the Faculty Mentor: Dr. Vanessa Troiani, (ADMI lab associated Lorenz curve. By measuring the evolution of director), NEUROSCIENCE the Gini coefficient over time, we can estimate whether Funding Source: Summer Autism and international trade helped or hindered addressing Neurodevelopmental Disorders Internship (SANDI) economic inequality among the participants in the global trade network. Measuring Concordance of Subtype Sulcogyral Patterns in Monozygotic and Dizygotic Twin Pairs The brain’s surface is made up of sulci (grooves) and gyri (ridges) that together create the distinct folded (sulcogryal) appearance of the brain. It is known that individual differences in the sulcogyral pattern of the orbital frontal cortex (OFC) can lead to variation in BU C K N E L L U N IVE R SIT Y 13
social behaviors and psychiatric pathology. Recent instructions of increasing syntactic complexity. Results research has focused on the sulcogyral folding pattern revealed that maternal education was the strongest variations in individuals, specifically within the OFC. predictor of both maternal linguistic input and child Four pattern types have been identified based on the receptive language outcomes. Syntactic complexity continuity of four distinct sulci, and subtypes within of input was the only measure that mediated the each pattern type have been defined that offer more relationship between maternal education and child fine-grained characterization of OFC structure. To receptive language skills. These findings critically date, there have been no analyses of OFC sulcogyral identify which early environmental factors are patterns (or subpatterns) and genetic associations. The mechanistically related to SES disparities in children’s goal of this project is to categorize the OFC pattern language development, and provide implications for subtypes of monozygotic (MZ) and dizygotic (DZ) reducing these disparities. twin pairs to explore whether the development of OFC pattern types have a strong genetic component. The study is accomplished using a publicly available Wutt Hmone Thin Kyi ’22 structural MRI data set from the Human Connectome Faculty Mentor: Professor Karlo Malaga, BIOMEDICAL Project (HCP). We used neuroimaging software to ENGINEERING individually subtype 570 subjects in the data set Funding Source: Program for Undergraduate Research 2020 and we are currently investigating the association Effect of White Matter Stimulation on with genetics. MZ twin pairs are expected to have Clinical Outcomes in Thalamic Deep Brain more similar subtypes (increased concordance) Stimulation for Essential Tremor than DZ twin pairs. The results of this project will lay Deep brain stimulation (DBS) is a surgical procedure the groundwork as the first study of the genetics of where electrodes are implanted in the brain before OFC sulcogyral patterns and may contribute to the stimulating the tissue with electricity. DBS of the early identification of preliminary markers of brain ventral intermediate (VIM) nucleus of the thalamus disorders. and the subthalamic nucleus (STN) are established treatments for the motor symptoms of essential Klaudia Kulawska ’21 tremor (ET) and Parkinson’s Disease (PD), respectively. Faculty Mentor: Professor Judith Grisel, PSYCHOLOGY Motor outcomes, such as tremor, rigidity, and Funding Source: N/A bradykinesia, after VIM and STN DBS can vary considerably across patients and strongly depend The Implications of Socioeconomic Status on the location of stimulation relative to the surgical on Maternal Language Input and Child target. Previous research suggests that stimulation Language Outcomes of the white matter (WM) tracts lateral to the VIM, Early language development is associated with the gray matter (GM) target, results in better DBS children’s socioeconomic status (SES). Specifically, outcomes. The objective of this retrospective study children from lower SES backgrounds, on average, is to determine how the spread of stimulation to exhibit slower language development compared WM during VIM DBS relates to therapeutic and non- to their peers from higher-SES backgrounds. Even therapeutic outcomes in ET patients. For the first though SES is a multidimensional construct, research phase of this research, a MATLAB algorithm that can often relies on a single dimension or a composite differentiate brain tissues, such as WM, GM, and measure when studying child language development. cerebrospinal fluid, from medical imaging based on In this article, I investigate four dimensions of SES, tissue anisotropy was developed. Patient-specific including maternal education, income-to-needs ratio, tissue anisotropy was derived from diffusion tensor financial security, and neighborhood SES. I examine imaging data acquired for individual patients who relationships amongst these different dimensions of received DBS (n = 22). To evaluate the performance of SES, the quantity and quality of maternal linguistic the algorithm, it has been trained and tested across input, and child receptive language skills. Mothers both ET and PD patient data sets. This algorithm can and their 36-40 months old children (n=267 dyads) be used to differentiate brain tissues in any region were video recorded during a 15-minute free play of interest. The modeling framework utilized in this session. Three measures of maternal linguistic input study could be used to identify optimal stimulation were derived from verbatim transcripts, including one sites on an individual basis, thereby improving clinical quantitative measure (number of words spoken) and outcomes. two qualitative measures (lexical diversity and syntactic complexity). Children’s concurrent receptive language skills were measured by a standardized measure of children’s ability to receive, process, and execute oral 14 KALMAN RE S EA R C H S Y M PO S I UM
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