Rete Aging: Il ruolo del Geriatra - Fabrizia Lattanzio Direttore Scientifico IRCCS INRCA
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Rete Aging: Il ruolo del Geriatra Fabrizia Lattanzio Direttore Scientifico IRCCS INRCA Ministero della Salute Roma, 12 luglio 2018 1
Identifying an at-risk older population: FRAILTY • Frailty is a common geriatric syndrome associated with aging • Around 10% of people aged over 65 years have frailty, rising to between a quarter and half of those aged over 85 years. Frailty is defined as a state of increased vulnerability resulting from aging and often disease associated decline in reserve and function across multiple physiologic systems such that the ability to cope with acute stressors is reduced Frailty is associated with increased risk of adverse health outcomes such as: functional decline, disability, repeated falls, reduction of the quality of life, repeated hospitalizations, nursing home admission 9 and death.
Multimorbidity: definitions • Co-occurrence 2 or more chronic diseases • Coexistence of two or more chronic conditions, where each must be a non- communicable disease, a mental health disorder or an infectious disease of long duration (WHO 2016) • Presence of 2 or more long-term health conditions, which can include: • defined physical and mental health conditions such as diabetes or schizophrenia • ongoing conditions such as learning disability • symptom complexes such as frailty or chronic pain • sensory impairment such as sight or hearing loss • alcohol and substance misuse (NICE 2016)
Italia Longeva Rete nazionale di ricerca sull’invecchiamento e la longevità attiva Associazione istituita da Ministero della Salute, Regione Marche e IRCCS INRCA, che dal 2012 opera per: § consolidare la centralità degli anziani nelle politiche di sviluppo § fronteggiare le crescenti esigenze di protezione della terza età § porre l’anziano come protagonista della vita sociale § guidare la Rete degli IRCCS per l’Invecchiamento per coordinare e promuovere la ricerca sull’ invecchiamento in Italia e in Europa §Soci Fondatori: 15
Rete degli IRCCS per l’Invecchiamento 16
Aree di interesse e sinergie AREE DI INTERESSE MODELLI ASSISTENZIALI INVECCHIAMENTO IN ASSESSMENT BIOGERONTOLOGIA TECNOASSISTENZA MULTIMORBIDITA’ INTERVENTI TEMI GENERALI FRAGILITA’ SALUTE ARMONIZZAZIONE PROCEDURE LINEE GUIDA ETICA / END of LIFE BIG DATA BIOBANCHE 17
From bench to bedside The IRCCS Network roadmap Network infrastructure Cutting-edge Measuring Translating Exploiting research New findings Older population Clinical studies Disseminating knowledge Genetics Epidemiology Assessment Exchange of knowledge Proteomics Harmonization Clinical application Guidelines Metabolomics Outcomes Innovative interventions Capacity building Biomarkers Real-world population Strong evidence New technologies Ethics Reverse translation
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Frailty models -The phenotype model -The cumulative deficit model -Prisma 7 questionnaire -Timed up and go test (TUGT) -Self-Reported Health -GP assessment -Comprehensive geriatric assessment -The Groningen frailty indicator questionnaire -Short Physical Performance Battery (SPPB) -Walking speed (gait speed)…. 20 Young J., British Geriatric Society, 2014
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