REPAIR OF ENDOGENOUS DNA DAMAGE - 6TH EU-US CONFERENCE ON - September 24th-28th 2017 University of Udine, Italy
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September 24th-28th 2017
WITH THE COLLABORATION OF:
University of Udine, Italy
UNIVERSITÀ
DEGLI STUDI DI TRIESTE
6TH EU-US CONFERENCE ON REPAIR OF ENDOGENOUS DNA DAMAGE
6TH EU-US CONFERENCE ON
REPAIR OF
ENDOGENOUS
DNA DAMAGE
The uniqueness of this series of meetings is its focus on the cellular responses to naturally formed genomic damage, and the relationship of defects in these responses to genetically inherited disor- ders associated with cancer predisposition, neuro- logical deficits and premature aging. Understanding the contributions of endogenous DNA damage to human disease, in particular cancer, and the patho- logical changes associated with aging is indeed the major theme of this conference. Recently, there has been an explosion-like increase of information on cancer genomes; the develop- ment of novel technologies for genome editing; vi- sualizing DNA repair complexes; the role for RNA in genome stability; novel mechanisms of DNA re- pair and epigenetics; and the role of aging and en- vironmental exposures in genome stability. A major goal of this meeting is to foster collaborative re- search on the cellular processes that affect ge- nomic instability in cancer. The role of endogenous DNA damage, in particular oxidative DNA damage, as a driver of normal and accelerated aging and the study of premature aging syndromes remain impor- tant areas of interest. Insights from rare inherited human diseases with defects in the DNA damage response continue to illuminate links between en- dogenous DNA damage and cancer, aging and neurologic disease. To promote the translation of knowledge about the sources and repair of endogenous DNA lesions into interventions that improve global human health, this meeting will stimulate collaborative translational re- search focused on the identification of new thera- peutic targets and the development of treatment strategies that either regulate DNA repair pathways in order to enhance cancer treatment, delay neu- rodegeneration, or reduce the pathological changes associated with aging.
A key objective of the 2017 meeting is to provide Organization
an environment for both early career and senior in-
vestigators of diverse backgrounds to communi-
cate their latest results on relevant scientific topics
and establish interactions that will not only
strengthen the numerous basic science and trans-
lational research efforts in this arena, but also en-
hance the development of the next generation of
researchers.
Thanks to the presence of about 40 invited speak- Organizing Committee Private sponsors: Local Organization Committee Official email address:
ers, the conference welcomes about 300 partici- Robert W. Sobol (USA), Eugenia
Dogliotti (Italy), Alexander Bürkle
Dr. Maria Cristina
Novelli-Quadrifoglio
Scientific and Logistic Program: conferencednarepair2017@uniud.it
Prof. Gianluca Tell
pants from all over the world: scholars, researchers, (GER) and Gianluca Tell (ITA) are
the Conference Organizers. Mr Sergio Bertossi gianluca.tell@uniud.it
Acknowledgments
+39.0432.494311
doctors, graduate students, technologists. About The Local Conference Dr. Paolo Ermano We acknowledge all the people
Organizers are as follows: Sponsor Companies: who, to different extents,
130 students from Universities of Udine and Trieste Gianluca Tell (University of Mettler Toledo
paolo.ermano@uniud.it
+39.328.1912722 contributed to the realization of
Udine), Claudio Brancolini the Conference.
will participate in the meeting and about 170 inter- (University of Udine), Gianni Del Biomolecules Prof. Angelo Vianello
Institutional representatives:
Sal (University of Trieste), Stefan angelo.vianello@uniud.it
national delegates will attend. Therefore, this meet- Schoeftner (University of Trieste)
Genomic Vision +39.0432.558781 Stefano Balloch, Sergio Bolzonello,
Marina Brollo, Silvio Brusaferro,
and Paolo Ermano (University of
ing will create an environment where young Udine). Local Sponsor Companies:
Prof. Francesco Nazzi
francesco.nazzi@uniud.it
Alessandro Cavarape, Paolo
Ceccon, Alberto Felice De Toni,
scholars and scientific experts from different fields National and International
institutions that have joined the
AMGA, Udine
+39.0432.558513
Prof. Claudio Brancolini
Massimo Di Silverio, Andrea
Garlatti, Furio Honsell, Vincenzo
share the latest results on these important research committee to support the
organization of this prestigious
Dorigo
D’AnnataWines
claudio.brancolini@uniud.it
+39.0432.494382
Martines, Cristiano Shaurli,
Bruno Stefanon, Edi Turco,
topics, and establish relationships that will not only conference through logistics,
persons or economic support are: Arbea Dr. Silvano Piazza Alessandro Venanzi.
silvano.piazza@unitn.it
strengthen research efforts on this scientific field, University of Udine (Italy) AUTONORD FIORETTO +39.0461.314440 Personnel from the University
but can positively influence the growth of a new University of Trieste (Italy)
School of Advanced Studies, Scholarships for Students
Book of Abstracts of Udine: Luca Bazzichetto,
Stefano Bonomi, Silvia Burra,
generation of scientists. Trieste (SISSA) and Post-Docs Dr. Giulia Antoniali
giulia.antoniali@uniud.it
Erika Codarin, Marta Codrich,
Plinio De Zorzi, Silvia Lolini,
Istituto Superiore di Sanità (Roma) We planned a total of 12 +39.0432.494313 Giovanna Mangiapane, Patrizia
University of South Alabama (USA) scholarships for students and Nacci, Anna Paulet, Renato
postdoctoral fellows. These Dr. Matilde Clarissa Malfatti
In the 2017 edition, as a special guest, Tomas Lin- University of Konstanz (DE) scholarships will be handed out malfatti.matildeclarissa@gmail.com
+39.0432.494313
Spoletti.
AREA Science Park, Trieste in the form of reimbursement for Students of the School of
dahl, the 2015 Nobel Laureate in Chemistry, will Friuli Innovazione (Udine) travel expenses and registration Dr. Marco De Anna Biotechnology from the
discounts for Congress marco.deanna@uniud.it University of Udine: Gabriele
present the Opening Lecture. He has substantially Consorzio per la Biomedicina participation. The funds will be +39.0432.556273 Coluccino, Annachiara Crosato,
Molecolare, CBM, Trieste used primarily to offset the cost De Tchadjet Olive, Alice Della
contributed to the discovery of the mechanisms of National Institutes of Health, of travel and registration for 6 Administrative Marina, Francesca De Vecchi,
fellows from the United States Alessandro Fornasaro, Berenice
repair of DNA damage caused by reactive oxygen NIH (USA)
Associazione Italiana
and 6 fellows from Europe
and Secretary Office: Furlan, Alice Gaiatto, Martina
selected by the Organizing Dr. Nila Colledani Giacomini, Kokallaj Mirela,
species that are involved in many human diseases per la Ricerca sul Cancro (AIRC) Committee, from the submitted nila.colledani@uniud.it Martina Lisa, Sofia Mastroianni,
Piano Lauree Scientifiche - MIUR abstracts, based on the quality +39.0432.494300 Lara Minisini, Manuela Orlandi,
including aging. Fondazione Fegato of the presented work. Dr. Giacomo Meula Stefano Pezzella, Anita Pitassi,
giacomo.meula@friuliforma- Ilaria Rosso, Arianna Sandron,
Fondazione Friuli Funds for scholarship are Anna Sbalchiero, Francesca
sponsored by Dr. Maria Cristina zione.it
Promoturismo FVG +39.0432.276402 Sbuelz, Damiano Tosolini,
Novelli-Quadrifoglio and Dr Cristina Totis.
Comune di Udine Sergio Bertossi in the memory of +393498174128
Comune di Cividale Prof. Franco Quadrifoglio for his Mrs. Marina Dorligh Photographers: Giancarlo Cro
unforgettable contribution to the marina.dorligh@uniud.it and Sofia Tell.
Fondazione De’ Claricini development and dissemination +39.0432.49494202
Aeronautica Militare Italiana of Molecular Biology at the Dr. Valentina Molignoni
University of Udine. The Organizing Commitee also
Bachelor School of Biotecnologies Scholarships are also funded in valentina.molignoni@uniud.it wishes to thanks:
and Master School in Molecular part by Associazione Italiana per +39.0432.494905
Biotechnologies, University of Udine Simone Bordon, Maria Serena
la Ricerca sul Cancro (A.I.R.C.). Mrs. Marilena Migliorati Bruno, Roberto Vicario.
Postgraduate School of Geriatrics, marilena.migliorati@uniud.it
University of Udine +39.0432.494303
PhD in Biomedical Sciences Mrs. Manuela Tomad
and Biotechnologies, manuela.tomad@uniud.it
University of Udine +39.0432.494301
2 | 6TH EU-US CONFERENCE ON REPAIR OF ENDOGENOUS DNA DAMAGE, UDINE (ITALY) 6TH EU-US CONFERENCE ON REPAIR OF ENDOGENOUS DNA DAMAGE, UDINE (ITALY) | 3
UniVErSitY of UdinE
paLaZZo antonini
Location
The University projects at the national and international it offers all those opportunities typical of
level. The present number of students en- bigger centers: traditional “osterie” (eater-
The meeting is held at the University of
rolled at the University is approx. 17000. ies), pubs, wine bars, cafes, restaurants,
Udine (http://www.uniud.it).
pizzerias, theaters, cinemas, discos, mu-
Udine and its University are a point of ref-
This venue was chosen because it offers seums, and shopping malls among the
erence in a region which is historically
a unique informal interactive environment biggest in Europe.
known as a meeting place and the cross-
in the charming City of Udine, in the Re-
roads of different worlds and cultures. Ge- A relaxing walk through the city centre
gion called Friuli Venezia Giulia in the
ographically situated in the centre of the brings the visitor to the Museo Diocesano
North East region of Italy, in the centre of
European Union, the University of Udine where one can appreciate the beauty of
Europe, close to Venice and Slovenia. The
plays an active role in a close network of Giambattista Tiepolo frescos and, cross-
Area has been recognized as one of the
relations, committed to sharing its knowl- ing one of the most beautiful venetian
best destinations in the World from the
edge and ideas. Since its establishment, squares on terra firma (“Piazza Libertà”),
Lonely Planet – Best in Travel 2016 to reach, in a refined context, a great vari-
Udine University has pursued the policy of
agency (http://www.turismofvg.it/). Udine ety of coffee bars, pastry shops, wine-
internationalisation, aimed at preparing
is a city at the centre of Europe that has tasting shops, pizzerias and restaurants.
students and forging relations and part-
been chosen because it can offer a unique
nerships with universities and institutions Over the past several years, Udine has
atmosphere to develop collaborations. In- in Europe and the rest of the world.
deed, the city will allow optimal interaction been host to several special national and
between participants, ensuring different Udine University collaborates not only international events: Udin&Jazz, refined
moments of inspiring collaborations be- within Europe but across the globe and and interesting jazz festival with interna-
tween American and European scientists. has long-standing connections with Africa, tional artists; Vicino/Lontano and the pre-
In addition, in the city several promotional India and China. mio Tiziano Terzani, which involves the
events of this congress have been orga- world of international literature, for a de-
nized in order to diffuse knowledge and bate on contemporaneity topics. The Far
awareness on the topics discussed. The City East Film Festival is another important big
Udine (https://www.visit-udine.it/en/) is a event, hugely acknowledged and appreci-
The University of Udine was founded in ated in its gender. Friuli Doc is the well-
1978 as part of the reconstruction plan of small city of 100,000 inhabitants; it has a
bourgeois and refined heart, surrounded by renowned as a wine-culinary regional
Friuli after the earthquake in 1976. Its aim kermesse that calls thousands of atten-
was to provide the Friulian community typical small and dynamic rural villages
whose architectures testify their rural origin. dees. In the last years Udine hosted great
with an independent centre for advanced pop and rock music shows with Madonna,
training in cultural and scientific studies. Udine is worldwide recognized for the Coldplay, Bruce Springsteen, U2, Bon
The University currently has the following number of its bookshops and this aspect Jovi, Pink Floyd etc..
degree programmes: Agriculture, Biotech- unveils the nature of this people, also re-
freshing the ancient pleasure of being the The theatrical movement is very lovely and
nologies, Economics, Engineering, Law, active with the main theatre Giovanni da
Modern Languages, Communication and third city, after Milan and London, to pro-
vide public lighting installations in the early Udine characterized of a traditional pro-
Training, Humanities, Medicine and gramme, and the more experimental
Surgery and Mathematics, Computer Sci- 20th century.
Teatro Contatto, particularly dedicated to
ence and Multimedia. In line with the times, Udine claims an ex- young people and students.
The University is actively involved in stu- cellent optical fibre net that guarantees an
dent and staff exchange projects with uni- ultraspeed internet connection.
versities within the EU and is currently Udine is highly appreciated for its quality The Territory
engaged in close collaboration with sev- of life, it has a good bike sharing service Friuli Venezia Giulia, small land situated at
eral universities from Eastern Europe and which allows one to reach numerous sites the north-east of Italy, in the middle of the
other non-EU countries. Moreover, the such as theaters, cinemas, museums and European landscape, in the past stage of
University participates in many research the several University branches. Moreover, wars and incessant changes of borders
UdinE
Loggia dEL LionELLo
4 | 6th EU-US ConfErEnCE on rEpair of EndogEnoUS dna damagE, UdinE (itaLY) 6th EU-US ConfErEnCE on rEpair of EndogEnoUS dna damagE, UdinE (itaLY) | 5
Law and EConomiCS CampUS between Italy, Slovenia and Austria, in heavily stroken by an earthquake, and The Miramare Castle stands on the peak
ConfErEnCE room these days shows its treasures: completely demolished by another in of a rock in the Gulf of Trieste. It was built
1976. Rebuilt “as it was and where it was” by Archduke Ferdinand Maximilian of
In the land of floodings (south of Friuli) in
has in the dome the symbol of “earthquake Hapsburg in the mid-nineteenth century
186 B.C. Aquileia was born as a military
and rebirth”. Nowadays all the city is hon- as a residence for himself and his wife,
settlement, the second latina estabilished
oured as Italian national monument and Charlotte of Belgium. From the castle, you
by the roman empire to protect it from the
this year elected the most beautiful village can enjoy a magnificent view of the Gulf
invasions of the Gauls. It was the east
in Italy (borgo dei borghi 2017). of Trieste and in its rooms you can admire
gate of the empire Unesco heritage from
many of the original furnishings. The cas-
1998, had a past of richness due to pros- A colony built by the Romans on the hills
tle is surrounded by a lush park consisting
perous trade, facilitated by water paths with an urban implant of “cardo e de-
of hundreds of exotic plants.
and a tremendous river harbor near the cumano” Cividale del Friuli became Un-
sea. Roman Aquileia, Christian Aquileia, in esco heritage in 2011. Favorite location of
medieval age was elected the second the langobardic dukedom, later became
Venues for the inaugural
capital city after Milan, and nowadays the abode of the aquileians patriarchs. Be-
and the scientific sessions
continues to disclose a fascinating history cause of the heavy destructions suffered
disclosed and written with the large con- during the second World War, Cividale The inaugural session will be held at the
tribution by the University of Udine with took the honor with the silver military Teatro Giovanni da Udine, which is the
archeological digs and laboratories. Once medal. Nowadays Cividale shows itself as main Theatre of the City with the presence
upon a time, it was second only to Rome a small pearl around the green Natisone of the main Local Political and Institutional
in matter of political influences, being for river; in the middle ages it was the capital representatives (www.teatroudine.it/).
all the medieval era the biggest diocese in city of the region with the name Forum The meeting sessions will be held in the
Europe. In the cathedral, we can find a Julii, giving later the name of the entire re- Economic Pole building that can accom-
kaleidoscope of transformations occurred gion Friuli. During the franks dominion it modate up to 430 people classroom style
during the centuries; behind the cathedral became Civita Aaustriae, city of the south- and has adjacent space that will be used
we may find the cemetery where were ern region of the reign, where Udine was to serve coffee and light refreshments dur-
buried the first soldiers died in the Carso named “la terra grande”. ing breaks and for display of the posters
area during the first World War; later one (goo.gl/maps/QtBTKNzbuWt).
Udine, protected by the alps, with the
of those had been buried in the symbolic
open spaces of the friulian plain and, to- This arrangement will permit increased
monumental grave of the Milite Ignoto at
wards south, the lagoon and the sea; “terra visibility of the posters, which will foster
the Vittoriano in Rome.
grande”, dominated by the aquileian patri- further interactions between the younger
The ample friulian plain inspired a group archate first, then homeland of Friuli under and more senior investigators attending
of Venetian notables the realization of an the venetian dominion, is the center of the the meeting. AV equipment and support
idea: in 1593, during the Venetian domin- ideal geographic compass which allows will be provided by the University of
ion, born the perfect fortress for a strong the visitor to reach the borders of a varied Udine. All places have free high-speed in-
defense from the Turkish invasions. Its region in the range of one hour (from the ternet access. Meals designated in the
name was Palma. Its nine-head-star mountains to the sea), a land defined in the Program will be served in the nearby cafe-
shape had been one of the most demand- nineteenth century by the poet Ippolito teria, onsite. Vegetarian alternatives will be
ing enterprises in Venice history, symbol Nievo “the summary of the Universe”. available at all meals.
of strength and wisdom of the republic.
Trieste (www.turismofvg.it/Localita/Trieste)
The perimetral wall, strengthened by
is a Roman city approximately from 50 b.
Napoleon Bonaparte who renamed the
C. In it are conserved the ruins of the Foro
city Palmanova (Unesco heritage in
and the Theater. After being repeatedly
2017), remained to defend a military com-
raided during the barbarian invasions and
pound which had never been involved in
following the Frankish domination, the city,
any battle. Perfectly synthesizing the joint
at the beginning of the XI century, began
of both civil and military architectures, it
to revive. In 1382 the development of Tri-
won the most important challenge against
este is restricted by the Republic of Venice,
the madness of nazists, whose projects
which ruled the Adriatic Sea. Hence, the
were to completely destroy it.
town decides embrace the Hapsburg influ-
Nestled at the feet of the giulian alps, Ven- ence. Under Maria Teresa of Austria’s reign
zone, the only “stone” of 4th century in all (XVII century) the city establishes itself as
the region, splendid example of architec- an important commercial port, by taking
tonic and artistic refurbishment. Venzone the urban appearance that one can admire
was the staging post towards the north today. In 1918 Trieste becomes a part of
along the roman via Julia Augusta, rich and Italy, but after the Second World War, it is
flourishing city during the Aquileian Patri- once more limited, this time by the Iron
archate, so much to enforce itself with Curtain. Trieste, by being a city on the bor-
walls, castles and the moat, unfortunately der, has become an important multicultural
suffered several invasions before the year and multi-religious centre, which takes
1000. It had been dominated by Napoleon pride in its prominent university centre and
Bonaparte first, then by Austrians, in 1866 cultural environment whilst searching for
entered in the Italian Reign. In 1348 was its role in today’s Europe.
Law and EConomiCS
ConfErEnCE bUiLding
6 | 6th EU-US ConfErEnCE on rEpair of EndogEnoUS dna damagE, UdinE (itaLY) 6th EU-US ConfErEnCE on rEpair of EndogEnoUS dna damagE, UdinE (itaLY) | 7
program
SUndaY mondaY 12:40-13.00
SEptEmbEr 24, 2017 SEptEmbEr 25, 2017 Speakers chosen from submitted
tEatro aULa 3, Law and abstracts
gioVanni da UdinE EConomiCS CampUS 12:40
Nima Mosammaparast
The ASCC complex mediates
15:00-17:00 8:30-10:40 a ubiquitin-dependent signaling
Registration SESSION 1 - REPLICATION STRESS axis specific for ALKBH-mediated
17:00-17:50 8:30 demethylation repair
Welcome Alexander Bürkle - Session Chair 12:50
17:00-17:15 8:40 Alex Pines
Gianluca Tell Hocine Mankouri TRIC chaperonin control transcription
Welcome and Introductory Remarks Analysis of replication-associated after UV damage by regulating Cockayne
17:15-17:45 mutagenesis at a single stalled replication fork Syndrome protein A
Institutional Welcomes 9:10 13:00-14:30
Prof. Alberto Felice De Toni Dana Branzei LUNCH – provided at the Cafeteria
Rector of the University of Udine Molecular studies of DDX11/Chl1 of ‘Renati Campus’
Other Institution Welcome Addresses helicase implicated in the Warsaw
breakage syndrome
17:45-19:00 14:30-16:30
Opening Plenary/Keynote Lecture 9:40 SESSION 3 - REGULATORY
Matthias Dobbelstein MECHANISMS OF RNA FUNCTIONS
17:45-18:00 p53 and checkpoint signaling as
Eugenia Dogliotti IN GENOME STABILITY
determinants of DNA replication stress
Opening Keynote Introduction 14:30
10:10 Gianluca Tell - Session Chair
18:00-19.00 Alessandro Vindigni
Tomas Lindahl New mechanisms of replication stress 14:40
Nobel Prize for Chemistry 2015 response to cancer chemotherapeutics Martin A.M. Reijns
Enzymatic surveillance Genome-embedded ribonucleotides
10:40-11:00 the good, the bad and the ugly
of DNA instability Coffee Break
15:10
19:30-22:00 Francesca Storici
Buffet (sponsored by the Organizers) 11:00-13:00 DNA repair by template RNA
for the Invited speakers SESSION 2 - DNA EDITING:
and paying Registrants 15:40
MECHANISMS UNDERLYING Fabrizio D’Adda di Fagagna
MUTATIONAL SIGNATURES The role of non-coding RNA in the DNA
IN HUMAN CANCERS damage response
Spouse Program 11:00 16:10
(Optional and fee-paying Robert W. Sobol - Session Chair Hilde Nilsen
with limited availability): 11:10 Implication of SMUG1 RNA processing
11:30-12:30 Ludmil Alexandrov activity for telomere maintenance
Guided visits to historical Udine Signatures of mutational processes 16:30-17:00
in human cancer Coffee Break
11:40 17:00-19:00
David H. Wilson III Poster Session
Repair mechanisms
for endogenous DNA damage 19:00
DINNER - on your own
12:10 (different choices will be proposed)
Samuel H. Wilson
Modulating the DNA polymerase reaction
equilibrium through chemical biology Spouse Program (Optional
and fee-paying with limited availability):
11:30 or 17:45
Guided visits to historical Udine
6th EU-US ConfErEnCE on rEpair of EndogEnoUS dna damagE, UdinE (itaLY) | 9
tUESdaY 12:40 wEdnESdaY 11:40 thUrSdaY 12:40-13.00
SEptEmbEr 26, 2017 Boris Pfander SEptEmbEr 27, 2017 Haico Van Attikum SEptEmbEr 28, 2017 Speakers chosen from submitted
aULa 3, Law and Chromatin constitutes a bottleneck in the aULa 3, Law and Regulation and dynamics of DNA repair in aULa 3, Law and abstracts
EConomiCS CampUS response to double strand breaks EConomiCS CampUS a chromatin context EConomiCS CampUS 12:40
13:10-14:30 12:10 Jeo Seok Han
LUNCH – provided at the Cafeteria of Conchita Vens Control of DNA damage response and
8:30-10:30 ‘Renati Campus’ 8:30-10:30 Towards radiotherapy and PARP inhibitor 8:30-10:30 DNA repair by small molecules
SESSION 4 - NON-CANONICAL SESSION 7 - ADVANCED combination: mechanism and clinical SESSION 9 - DEFECTS IN THE DNA
ACTION AND NOVEL REGULATORS TECHNOLOGIES FOR ANALYSIS DAMAGE RESPONSE AS TARGETS 12:50
DNA polymerase β: The missing link of the
OF DNA REPAIR aspects Rajendra Prasad
14:30-16:30 OF DNA REPAIR AND FOR PERSONALIZED THERAPEUTIC
8:30 SESSION 6 - STABILITY THE DNA DAMAGE RESPONSE APPROACHES
Eugenia Dogliotti - Session Chair OF THE GENOME IN AGING 12:40-13.00 base excision repair machinery in
8:30 8:30 mammalian mitochondria
8:40 AND NON-NEOPLASTIC DISEASE Alan Tomkinson - Session Chair Speakers chosen from submitted Robert W. Sobol - Session Chair
Patrick Sung 14:30 abstracts 13:00-14:30
8:40 8:40 LUNCH – provided at the Cafeteria of
Novel role of the BRCA1-BARD1 Eugenia Dogliotti - Session Chair Elisa Ferrando-May 12:40 Trey Ideker
complex in RAD51-mediated Muralidhar Hegde ‘Renati Campus’
14:40 Optical control and real-time imaging Mapping the DNA damage response
homologous recombination Björn Schumacher of DNA damage and repair New Mechanism of Genome damage and hierarchy by analysis of systematic genetic 14:30-16:00
9:10 Non-cell-autonomous regulation of the Repair defects in motor neuron disease: networks Closing Plenary
9:10 Role of TDP-43
John Tainer DNA damage response Michele Morgante 9:10 14:30
Flap endonuclease 1 employs DNA 15:10 NGS-based technologies for studying 12:50 Chris Bakkenist Robert W. Sobol
sculpting and phosphate steering to Tohru Minamino genome stability and structural diversity Sathya Balachander ATR kinase inhibitors attenuate radiation- Closing Keynote Introduction
ensure specific 5´-flap incision Ribose-seq upgraded: a robust technique induced T cell exhaustion and potentiate T
to prevent genome instability A critical role of cellular senescence in 9:40 14:40
metabolic and cardiovascular disease to map ribonucleotides incorporated in any cell activity in the tumor microenvironment Phil Hanawalt
Bret D. Freudenthal genomic DNA
9:40 APE1 cleavage mechanisms 9:40 From Repair Replication to R-loops in half-
Alan Tomkinson 15:40
Vilhelm Bohr during DNA repair 13:00-14:00 Randi Gussgard Syljuåsen a-century
Targeting mitochondrial DNA repair LUNCH – provided at the Cafeteria of Mechanisms and consequences of basal
in cancer cells DNA damage, neurodegeneration and 15:40
mitochondrial dysfunction ‘Renati Campus’ ATR/Chk1 activity in human cells Public announcement of the names
10:10 10:10-10.30 14:00-18:30 of the Travel Fellowships awardees
Jean-Marc Egly 16:10 Speakers chosen from submitted 10:10
Pier Giorgio Mastroberardino Guided visits to downtown Udine and to Nina Gustafsson for best Poster Presentation
Cockayne syndrome A and B proteins abstracts the UNESCO World Heritage Site Cividale
regulate transcription arrest through a DNA damage and repair in chronic Protecting the genome through metabolic 16:00
neurodegeneration 10:10 18:30 enzymes Gianluca Tell
ubiquitin/proteasome degradation process Altaf Wani
16:40-17:00 Dinner partially sponsored by the 10:40-11:00 Closing Remarks
10:40-11:00 Regulation of post-repair restoration Organizers
Coffee Break Coffee Break of epigenetic chromatin mark Coffee Break Silvio Brusaferro
Location: Villa DeClaricini (Director of the Department of Medicine,
17:00-19:00 10:20 (http://www.declaricini.it/)
Poster Session University of Udine):
11:00-13:00 Olga Lavrik 11:00-13:00 Thank you and Farewell
SESSION 5 - DNA DAMAGE, 19:00 Protein-protein interactions SESSION 10 – CELL TYPE AND DNA
EPIGENETICS AND DNA REPAIR DINNER - on your own operating in base excision DNA repair DAMAGE SPECIFICITY IN DNA REPAIR
11:00 (different choices will be proposed) 10:30-11:00 11:00 Spouse Program (Optional
David H. Wilson III - Session Chair Coffee Break Eugenia Dogliotti - Session Chair and fee-paying with limited availability):
11:10 Spouse Program (Optional 11:10 11:30 or 17:45
Roderick J. O’Sullivan and fee-paying with limited availability): Leona Samson Guided visits to historical Udine
11:00-13:00
Interrogating the mechanism 9:00-16:00 SESSION 8 - POLY(ADP-RIBOSYL)ATION Cell specific responses to alkylation and
of Alternative Lengthening of Telomeres Visit to the Roman city of Aquileia IN THE DNA DAMAGE RESPONSE: inflammation
11:40 (Basilica, Roman ruins and the exposition PRE-CLINICAL AND TRANSLATIONAL 11:40
Gaëlle Legube “Faces from Palmira”) and to the ASPECTS Bruce Demple
Chromosome and chromatin dynamics “Miramare Castle” in Trieste 11:00 Crosslinks produced during attempted
during DNA double strand break repair To be confirmed Alexander Bürkle - Session Chair DNA repair
12:10 11:30 or 17:45 11:10 12:10
Primo Schär Guided visits to historical Udine Françoise Dantzer Bernd Kaina
DNA repair mediated DNA demethylation Poly(ADP-ribose) polymerase 3 (PARP3) in DNA repair and death regulation in human
generates site-directed chromatin genome integrity and beyond myeloid immune cells
plasticity
10 | 6th EU-US ConfErEnCE on rEpair of EndogEnoUS dna damagE, UdinE (itaLY) 6th EU-US ConfErEnCE on rEpair of EndogEnoUS dna damagE, UdinE (itaLY) | 11LiSt
alexandrov Ludmil ideker trey Sobol w. robert
lba@lanl.gov trey.ideker@gmail.com rwsobol@mac.com
USA Los Alamos National Laboratory USA UC San Diego USA University of South Alabama Mitchell
Cancer Institute
bakkenist Chris kaina bernd
‘cjb38@pitt.edu’ kaina@uni-mainz.de Storici francesca
of SpEakErS USA University of Pittsburgh
bohr Vilhelm
vbohr@nih.gov
USA National Institutes of Health
GERMANY University Medical Center
Legube gaëlle
gaelle.legube@univ-tlse3.fr
FRANCE University of Toulouse
storici@gatech.edu
USA Georgia Institute of Technology
Sung patrick
patrick.sung@yale.edu
USA Yale University
branzei dana Lindahl tomas
dana.branzei@ifom.eu tomas.lindahl@crick.ac.uk Syljuåsen gussgard randi
ITALY The FIRC Institute of Molecular UK The Francis Crick Institute randi.syljuasen@rr-research.no
Oncology Foundation NORWAY Oslo University Hospital
mankouri hocine
bürkle alexander hocine@sund.ku.dk tainer John
alexander.buerkle@uni-konstanz.de DENMARK University of Copenhagen jatainer@gmail.com
GERMANY University of Konstanz USA The University of Texas MD Anderson
mastroberardino pier giorgio Cancer Center
d’adda di fagagna fabrizio p.g.mastroberardino@erasmusmc.nl
fabrizio.dadda@ifom.eu THE NETHERLANDS Erasmus University tell gianluca
ITALY The FIRC Institute of Molecular Medical Center gianluca.tell@uniud.it
Oncology Foundation ITALY University of Udine
minamino tohru
dantzer françoise t_minamino@yahoo.co.jp tomkinson alan
francoise.dantzer@unistra.fr JAPAN Niigata University Graduate School atomkinson@salud.unm.edu
FRANCE Strasbourg University of Medical and Dental Sciences USA University of New Mexico
demple bruce morgante michele Van attikum haico
bruce.demple@stonybrook.edu michele.morgante@uniud.it h.van.attikum@lumc.nl
USA Stony Brook University Medical School ITALY University of Udine THE NETHERLANDS Leiden University
Medical Center
dobbelstein matthias nilsen hilde
mdobbel@uni-goettingen.de hilde.nilsen@medisin.uio.no Vens Conchita
GERMANY University Medical Center NORWAY University of Oslo c.vens@nki.nl
Göttingen THE NETHERLAND The Netherlands Cancer
o’sullivan J. roderick Institute
dogliotti Eugenia osullivanr@upmc.edu
eugenia.dogliotti@iss.it USA University of Pittsburgh Vindigni alessandro
ITALY Istituto Superiore di Sanità Roma avindign@slu.edu
pfander boris USA Saint Louis University School of
Egly Jean-marc bpfander@biochem.mpg.de Medicine
egly@igbmc.fr GERMANY Max Planck Institute of
FRANCE Institut de Génétique et de Biologie Biochemistry wilson h. david iii
Moléculaire et Cellulaire wilsonda@mail.nih.gov
reijns a. m. martin USA National Institute on Aging, IRP, NIH
ferrando-may Elisa martin.reijns@igmm.ed.ac.uk
elisa.may@uni-konstanz.de UK The University of Edinburgh wilson h. Samuel
GERMANY Bioimaging Center of Konstanz wilson5@niehs.nih.gov
Samson d. Leona USA National Institutes of Health
freudenthal d. bret lsamson@mit.edu
bfreudenthal@kumc.edu USA Massachusetts Institute of Technology
USA University of Kansas Medical Center
Schär primo
gustafsson nina primo.schaer@unibas.ch
nina.gustafsson@scilifelab.se SWITZERLAND University of Basel
SWEDEN Karolinska Institute
Schumacher björn
hanawalt philip bjoern.schumacher@uni-koeln.de
hanawalt@stanford.edu GERMANY University of Cologne
USA Stanford University
12 | 6th EU-US ConfErEnCE on rEpair of EndogEnoUS dna damagE, UdinE (itaLY) 6th EU-US ConfErEnCE on rEpair of EndogEnoUS dna damagE, UdinE (itaLY) | 13LiSt of
akbari mansour baptiste beverly burger kaspar
Dr Dr PostDoc
University of Copenhagen, DENMARK National Institute of Environmental Health University of Oxford, UNITED KINGDOM
akbari@sund.ku.dk Sciences, USA kaspar.burger@path.ox.ac.uk
P69 beverly.baptiste@nih.gov P15
dELEgatES albelazi mustafa
PhD
University of Salford, UNITED KINGDOM
M.S.Albelazi@edu.salford.ac.uk
P34
bazlekowa-karaban milena
PhD
University of Warsaw, POLAND
m.bazlekowa@biol.uw.edu.pl
burra Silvia
PhD
University of Udine, ITALY
burra.silvia@gmail.com
P41
P39
alexeeva marina Caglayan melike
PhD bazzani Veronica PhD
University of Stavanger, NORWAY PhD National Institute of Environmental Health
marina.alexeeva@uis.no Sissa, ITALY Sciences, USA
P35 vbazzani@sissa.it melike.caglayan@nih.gov
P79 P42
ali reem
PhD berardinelli francesco Campalans anna
University of Nottingham, UNITED KING- Dr Researcher
DOM University Roma Tre, ITALY Commissariat à l’énergie atomique et aux
msxra29@nottingham.ac.uk francesco.berardinelli@uniroma3.it énergies alternatives, FRANCE
P8 anna.campalans@cea.fr
P72
allocca mariacarmela bjelland Svein
PhD PhD Carvalho dias gustavo
Massachusetts Institute of Technology, University of Stavanger, NORWAY PhD
USA svein.bjelland@uis.no Universidad Autónoma de Madrid, SPAIN
mallocca@mit.edu gcarvalho@cbm.csic.es
P19 P2
blanco Luis
alnajjar khadijeh Prof Cisneros g. andrés
PhD Centro de Biologia Molecular Severo PhD
Yale University, USA Ochoa, SPAIN University of North Texas, USA
khadijeh.alnajjar@yale.edu lblanco@cbm.csic.es andres@unt.edu
P36 P2 P67
alsøe Lene bolognesi Claudia Codrich marta
PhD Dr PostDoc
University of Oslo, NORWAY Unità di Cancerogenesi Ambientale Dept University of Udine, ITALY
lene.alsoe@medisin.uio.no Epidemiologia Clinica, ITALY mcodrich@gmail.com
P37 claudia.bolognesi@hsanmartino.it
antoccia antonio Coluzzi Elisa
Ass. Prof. borsuk Ewelina maria PhD
University Roma Tre, ITALY PhD Università degli studi Roma Tre, ITALY
antonio.antoccia@uniroma3.it Institute of Biochemistry and Biophysics elisa.coluzzi@uniroma3.it
PAS, POLAND
e.szmajda@ibb.waw.pl
antoniali giulia P1 Cukrov dubravka
PostDoc PhD
University of Udine, ITALY bosio maria Cristina University of Pisa, ITALY
giulia.antoniali@gmail.com Dr dubravkacukrov@gmail.com
P20 Università degli studi di Milano, ITALY P70
rampichinocri@yahoo.it
balachander Sathya P21 Curtin nicola
PhD Prof
Georgia Institute of Technology ,USA bosshard Sandra Newcastle University, UNITED KINGDOM
balachan@gatech.edu PhD nicola.curtin@ncl.ac.uk
P38 University of Lausanne, SWITZERLAND P88
sandra.bosshard@unil.ch
P40
6th EU-US ConfErEnCE on rEpair of EndogEnoUS dna damagE, UdinE (itaLY) | 15Czerwinska Jolanta Esbensen Qin Ying ishchenko alexander kurmasheva raushan maffia antonio mosammaparast nima
PhD PhD Dr PhD PhD PhD
Institute of Biochemistry and Biophysics University of Oslo, NORWAY UMR 8200 CNRS Paris Saclay, FRANCE The University of Texas Health Science Università degli Studi di Pavia, ITALY Washington University, USA
PAS, POLAND yinge@medisin.uio.no aishchen@gmail.com Center, USA antonio.maffia01@universitadipavia.it nima@wustl.edu
jczerwinska@ibb.waw.pl Kurmasheva@uthscsa.edu P54 P27
P44
ferino annalisa Jaruga pawel malacaria Eva muoio daniela
d’alessio barbara PhD Dr Landi Stefano PhD PhD
Master University of Udine, ITALY National Institute of Standards and Tech- Prof University La Sapienza, ITALY Università degli studi Roma Tre, ITALY
University of Pisa, ITALY ferino.annalisa@spes.uniud.it nology, USA University of Pisa, ITALY evamalacaria@gmail.com daniela.muoio@uniroma3.it
barbara.dalessio@irgb.cnr.it P47 jaruga@nist.gov slandi@biologia.unipi.it P4
P3 P90
fortini paola malfatti matilde Clarissa muzi-falconi marco
daley James Dr Jemth ann-Sofie Laurila niina PhD Prof
PhD ISTITUTO SUPERIORE DI SANITA’, ITALY PhD PhD University of Udine, ITALY University of Milano, ITALY
Yale University School of Medicine, USA paola.fortini@iss.it Translational Medicine and Chemical Biol- University of Oulu, FINLAND malfatti.matildeclarissa@gmail.com marco.muzifalconi@unimi.it
james.daley@yale.edu P48 ogy, SWEDEN niina.laurila@oulu.fi P85 P64
P45 annsofie.jemth@scilifelab.se P53
gervai Judit Zsuzsanna mangiapane giovanna orioli donata
de rosa mariarosaria MSc Lavrik olga PhD Dr
PhD Hungarian Academy of Sciences, HUN- karwowski boleslaw Prof University of Udine, ITALY IGM- CNR, ITALY
University Federico II of Naples, ITALY GARY Prof Institute of Chemical Biology and Funda- giovannamangiapane1@gmail.com orioli@igm.cnr.it
meryderosa@gmail.com jgervai@gmail.com Meical University of Lodz, POLAND mental Medicine, RUSSIA
P76 Boleslaw.Karwowski@umed.lodz.pl lavrik@niboch.nsc.ru
P51 P11/P78 marcon francesca oksenych Valentyn
dellino gaetano ivan ghahe Somayeh Shahmoradi Dr PhD
PhD PhD kassahun henok Lee Jong-Soo ISTITUTO SUPERIORE DI SANITA’, ITALY Institute of Cancer Research and Molecular
European Institute of Oncology, ITALY University of Warsaw, POLAND PhD PhD francesca.marcon@iss.it Medicine, NORWAY
gaetano.dellino@ieo.it s.shahmoradi@biol.uw.edu.pl Akershus univeristy hospital, NORWAY Ajou University, KOREA P48 valentyn.oksenych@ntnu.no
P74 P9 henok.kassahun@medisin.uio.no jsjlee@ajou.ac.kr P57
P91 martin peter
di masi alessandra götz alexandra PhD park Suhyung
Ass. Prof. PhD kohoutek Ji í Lee kyoo-young University of Salford, UNITED KINGDOM Dr
Roma Tre University, ITALY University of Oslo, NORWAY PhD Dr p.martin3@edu.salford.ac.uk Institute for Basic Science, SOUTH KROEA
alessandra.dimasi@uniroma3.it alexandra.gotz@medisin.uio.no Veterinary Research Institute, CZECH RE- Institute for Basic Science, SOUTH KOREA P92 winia27@ibs.re.kr
P16 PUBLIC klee2910@ibs.re.kr P6
kohoutek@vri.cz P22 menin Luca
diatlova Evgeniya han Joo Seok P86 PhD parlanti Eleonora
Master Dr Licata nausicaa Valentina University of Milano-Bicocca, ITALY Dr
Novosibirsk State University, RUSSIA Institute for Basic Science, SOUTH KOREA kope ná olga PhD l.menin1@campus.unimib.it ISTITUTO SUPERIORE DI SANITA’, ITALY
jannie.lapt@gmail.com jshan91@ibs.re.kr Research worker University of Trento, ITALY P5 eleonora.parlanti@iss.it
P33 P82 Institute of Biophysics of the CAS, CZECH nausicaa.licata@unitn.it
REPUBLIC miggiano riccardo
dizdaroglu miral harris reuben olga.kop@centrum.cz PostDoc pascucci barbara
PhD PhD P84 Lirussi Lisa Università degli Studi del Piemonte Orien- Dr
National Institute of Standards and Tech- Howard Hughes Medical Institute, USA Dr tale, ITALY Area della Ricerca Roma 1, ITALY
nology, USA rsh@umn.edu kosicki konrad University of Oslo, NORWAY riccardo.miggiano@uniupo.it barbara.pascucci@mlib.ic.cnr.it
miral@nist.gov P10 Dr lisa.lirussi@medisin.uio.no P56 P58
P43 / P50 Polish Academy of Sciences, POLAND P25
hedge mUraLidhar konrado@biol.uw.edu.pl milanese Chiara pennisi rosa
dzimková marta Ass. Prof P83 Loffredo rosa PostDoc PhD
PhD Houston Methodist Research Institute and PhD Erasmus Medical Center, THE NETHER- Università degli studi Roma Tre, ITALY
Masaryk University, CZECH REPUBLIC Cornell University, USA kroustallaki penelope University of Trento, ITALY LANDS rosa.pennisi@uniroma3.it
dzimkova@vri.cz mlhegde@houstonmethodist.org PhD rosa.loffredo@unitn.it c.milanese@erasmusmc.nl P59
P81 P71 University of Olso, NORWAY P26
pinelopi.kroustallaki@medisin.uio.no peripolli Silvia
Elder rhoderick inga alberto P24 Longo antonella mognato maddalena PhD
PhD Dr PhD PhD University College London, UNITED KING-
University of Salford, UNITED KINGDOM University of Trento, ITALY kumari bhavini Università degli studi Roma Tre, ITALY University of Padova, ITALY DOM
r.h.elder@salford.ac.uk alberto.inga@unitn.it PhD antonella.longo@uniroma3.it maddalena.mognato@unipd.it silvia.peripolli.16@ucl.ac.uk
INDIAN INSTITUTE OF TECHNOLOGY P80
PATNA, INDIA
bhavini@iitp.ac.in
P52
16 | 6th EU-US ConfErEnCE on rEpair of EndogEnoUS dna damagE, UdinE (itaLY) 6th EU-US ConfErEnCE on rEpair of EndogEnoUS dna damagE, UdinE (itaLY) | 17peterson Lisa rissech Joan frigola Serebrenik artur Villa matteo
PhD PhD PhD PhD
University of Minnesota, USA Institute for research in biomedicine (IRB University of Minnesota, USA Università di Milano Bicocca, ITALY
peter431@umn.edu Barcelona) sere0017@umn.edu matteo.villa@unimib.it
P93 joan.frigola@irbbarcelona.org P12 P7
pezone antonio Silvestrov pavel wagner J. richard
PhD rossi franca MS PhD
University Federico II of Naples, ITALY Researcher University of North Texas, USA Université de Sherbooke, CANADA
antoniopezone@gmail.com University of Piemonte Orientale, ITALY pavelsilvestrov@my.unt.edu richard.wagner@usherbrooke.ca
P60 franca.rossi@uniupo.it P75 P55/P62
P56
pines alex Stevnsner tinna walker alice
Dr rundle Stuart PhD PhD
Erasmus Medical Center, THE NETHER- MD Aarhus University, DENMARK University of North Texas, USA
LANDS Newcastle University, UNITED KINGDOM tvs@mbg.au.dk AliceWalker@my.unt.edu
a.pines@erasmusmc.nl stuart.rundle@gmail.com P49 P89
P28 P88
tesfahun almaz nigatu wani altaf
prasad rajendra russo antonella PhD PhD
Dr Prof University of Stavanger, NORWAY The Ohio State University, USA
National Institute of Environmental Health University of Padova, ITALY almaz.tesfahun@uis.no wani.2@osu.edu
Sciences, USA antonella.russo@unipd.it P66 P65
prasad@niehs.nih.gov P3
P94 thatte Jayashree wennerström anna
rzeszutek iwona PhD Mrs
prosperi Ennio PhD International Centre for Genetic Engineering Akershus University Hospital, NORWAY
Dr University of Bern, SWITZERLAND and Biotechology, ITALY annawen@medisin.uio.no
Consiglio Nazionale delle Ricerche, ITALY iwona.rzeszutek@izb.unibe.ch Jayashree.Thatte@icgeb.org
prosperi@igm.cnr.it P18 P29
P31 You panpan
Santorsola mariangela theil arjan PhD
radhakrishnan Sabarinathan Dr PhD University of Oslo, NORWAY
PhD University of Trieste, ITALY Erasmus Medical Center, THE NETHER- panpan.you@medisin.uio.no
Institute for Research in Biomedicine (IRB mariangela.santorsola@lncib.it LANDS
Barcelona), SPAIN a.theil@erasmusmc.nl
sabari.radha@irbbarcelona.org P30 Zabolotnaya Ekaterina
Saparbaev murat PhD
PhD tuppurainen hanna University of Cambridge, UNITED KING-
radicella J.pablo Gustave Roussy Cancer Campus, FRANCE PhD DOM
Dr smurat@igr.fr University of Oulu, FINLAND ez250@cam.ac.uk
Institute of Cellular and Molecular Radiobi- P23 hanna.tuppurainen@oulu.fi P77
ology, FRANCE P13
pablo.radicella@cea.fr Scalera Claudia Zappone antonina
P46 Dr turturro Sabrina Dr
IGM- CNR, ITALY PhD Sissa, ITALY
rawat Vipin scacla92@gmail.com Università degli studi Roma Tre, ITALY zappone.annie@gmail.com
PhD P73 sabrina.turturro@uniroma3.it P17
International Centre for Genetic Engineering
and Biotechology, ITALY Schaich matt Zarkovic gabriella
vipin.singh.rawat482@gmail.com PhD Venier paola PhD
P61 University of Kansas Medical Center, USA Prof University Paris-Saclay, FRANCE
Mschaich@kumc.edu Università degli Studi di Padova, ITALY gabriella.zarkovic@gustaveroussy.fr
recagni marta P63 paola.venier@unipd.it P32
Dr
Fondazione IRCCS Istituto Nazionale dei Schillaci odessa Zharkov dmitry
Tumori, ITALY Dr Vieru andra-Stefania Dr
marta.recagni@istitutotumori.mi.it University of Trieste, ITALY PhD Institute of Molecular and Cellular Biology,
P87 odessaschillaci@gmail.com Charles University, CZECH REPUBLIC RUSSIA
andra.vieru@img.cas.cz oxoguanine@gmail.com
P14 P68
18 | 6th EU-US ConfErEnCE on rEpair of EndogEnoUS dna damagE, UdinE (itaLY) 6th EU-US ConfErEnCE on rEpair of EndogEnoUS dna damagE, UdinE (itaLY) | 19LiSt of fVg
Abadi Zahra Jamali Rasht Bressan Chiara Curtolo Erica
University of Udine, Italy University of Udine, Italy University of Trieste, Italy
zj9203500@gmail.com bressanc97@gmail.com erica.curtolo@gmail.com
Albanesi Enrico Bucca Sebastian Cutano Valentina
University of Udine, Italy University of Udine, Italy University of Udine, Italy
StUdEntS immigrantsong@virgilio.it
Alfarè Lovo Matteo
University of Udine, Italy
teo.alfare@gmail.com
sebastian.zoldo@gmail.com
Buemi Valentina
Sissa, Italy
valentinabuemi@gmail.com
valentinacutano@gmail.com
De Iasi Cristina
University of Udine, Italy
cri-ki@libero.it
partiCipantS Antonini Marialuisa
University of Udine, Italy
antonini@infofactory.it
Argenti Carlotta
Busellato Ilaria
University of Udine, Italy
ilaria.busellato@gmail.com
Buzzelli Alice
De Luca Lorenzo Alvio
University of Udine, Italy
lorenzoalvio.deluca97@gmail.com
De Marco Simone
University of Udine, Italy University of Udine, Italy University of Udine, Italy
carlottaargenti.92@gmail.com alicebuzzelli@yahoo.it simonedemarco96@yahoo.it
Armellin Riccardo Caiazzo Giorgia De Rosa Valeria
University of Udine, Italy University of Udine, Italy University of Udine, Italy
riccardo.armellin98@gmail.com GiorgiaCaiazzo24@gmail.com derosa.valeria94@libero.it
Armenise Doriana Calligaris Matteo De Stefani Adele
University of Udine, Italy University of Udine, Italy University of Udine, Italy
armenise.doriana@spes.uniud.it calligaris.matteo@spes.uniud.it adele.deste@libero.it
Ayyildiz Dilara Camerer Sophia Diana Maria De Vecchi Francesca
University of Udine, Italy University of Udine, Italy University of Udine, Italy
dilarayyildiz@gmail.com sophia.camerer@outlook.it francescadevecchi.fdv@gmail.com
Bacchetti Giacomo Candotto Giulia Del Mestre Pierfrancesco
University of Udine, Italy University of Udine, Italy University of Udine, Italy
giacomo.bacchetti.95@gmail.com giulycandotto@libero.it pierfrancesco.delmestre@gmail.com
Bagolin Margherita Cela Ilaria Della Marina Alice
University of Udine, Italy University of Udine, Italy University of Udine, Italy
marghe899@gmail.com celailaria@gmail.com ali.dellamarina@outlook.it
Baschino Samantha Ciol Lorenzo Di Centa Laura
University of Trieste, Italy University of Udine, Italy University of Udine, Italy
samy.baschino@gmail.com lorenzo@fotociol.it dicentalaura@gmail.com
Bertoli Andrea Ciotti Sonia Drusin Andrea
University of Udine, Italy University of Udine, Italy University of Udine, Italy
andrea.bertpp@gmail.com s.ciotti90@hotmail.it andrea.drusin@libero.it
Bettini Paolo Coluccino Gabriele Duca Giacomo
University of Udine, Italy University of Udine, Italy University of Udine, Italy
paol.bett@gmail.com gabrielecoluccino96@hotmail.it jackduca97@gmail.com
Bier Francesca Copetti Paolo Ecca Fabrizio
University of Udine, Italy University of Udine, Italy University of Udine, Italy
francescabier@libero.it coppi97@live.it ecca.fabrizio@gmail.com
Bigo Angelica Croatto Martina Fagotto Valentina
University of Udine, Italy University of Udine, Italy University of Udine, Italy
angelicabigo6@gmail.com croatto3@gmail.com valentina.fagotto@icloud.com
Bortolus Gloria Crosato Annachiara Foffano Lorenzo
University of Udine, Italy University of Udine, Italy University of Udine, Italy
gloria.bortolus.bortolus@gmail.com annachiara.crosato@gmail.com foffano.lorenzo@spes.uniud.it
20 | 6th EU-US ConfErEnCE on rEpair of EndogEnoUS dna damagE, UdinE (itaLY) 6th EU-US ConfErEnCE on rEpair of EndogEnoUS dna damagE, UdinE (itaLY) | 21Fornasaro Alessandro Lemonche Gerard Boix Montanari Tommaso Pregnolato Grazia Vergolini Ettore University of Udine, Italy University of Udine, Italy University of Udine, Italy University of Udine, Italy University of Udine, Italy alessandrofornasaro@gmail.com boixlemonche.gerard@spes.uniud.it montanari.tommaso@spes.uniud.it grazia2308@gmail.com ettorevergolini@outlook.it Fortuna Nicolò Lera Cristina Moratti Massimo Racanelli Dominga Vuerli Martika University of Udine, Italy University of Udine, Italy University of Udine, Italy University of Udine, Italy University of Udine, Italy fortuna.nicolo@gmail.com cri.lera@libero.it massimo.moratti96@gmail.com domingaracanelli@gmail.com makefriconotwar@outlook.it Franforte Elisa Liberi Matteo Olivo Lia Radecka Dorota Zambon Alberto University of Udine, Italy University of Udine, Italy University of Udine, Italy University of Udine, Italy University of Udine, Italy elisa.franforte@gmail.com liberimatteo@gmail.com Lia.olivo997@gmail.com dradecka@yahoo.it alberto.zambon.94@gmail.com Furlan Berenice Lise Veronica Orlandi Manuela Ragazzon Elisa Zanon Alice University of Udine, Italy University of Udine, Italy University of Udine, Italy University of Udine, Italy University of Udine, Italy furlan.berenice@gmail.com lise.veronica@spes.uniud.it manuela.orlandi96@gmail.com elisa.ragazzon@gmail.com alice.zanon96@gmail.com Furlan Michela Londero Chiara Orlani Alice Rodaro Chiara Zappone Antonina University of Udine, Italy University of Udine, Italy University of Udine, Italy University of Udine, Italy Sissa, Italy mikela_furlan@hotmail.it chiaralondero@outlook.it alice.i403w@gmail.com rodaro.chiara@gmail.com zappone.annie@gmail.com Gaiatto Alice Marano Lorenzo Paluvai Harikrishnareddy Rosso Ilaria Zilio Chiara University of Udine, Italy University of Udine, Italy University of Udine, Italy University of Udine, Italy University of Udine, Italy gaiatto.alice@spes.uniud.it lorenz771.p66@gmail.com hari.paluvai@student.unisi.it ilariarosso94@gmail.com chiara.zilio97@gmail.com Giacomini Martina Marini Lorenzo Papa Nicole Sandron Arianna Zonta Laura University of Udine, Italy University of Udine, Italy University of Trieste, Italy University of Udine, Italy University of Udine, Italy giacomini.martina001@spes.uniud.it marinl0@alice.it nicole.papa@studenti.units.it arianna.sandron@gmail.com laura-284@hotmail.it Godeas Grazia Martin Asia Amelia Pavan Eleonora Sbalchiero Anna University of Udine, Italy University of Udine, Italy University of Udine, Italy University of Udine, Italy grazia.godeas@hotmail.it asiamartin95@gmail.com pavan.eleonora@gmail.com sbalchiero.anna@spes.uniud.it Goi Jessica Martina Lisa Perosa Gianluca Sbuelz Francesca University of Udine, Italy University of Udine, Italy University of Udine, Italy University of Udine, Italy jessigoi@hotmail.it martina.lisa@spes.uniud.it gianpero1912@gmail.com francescasbuelz@gmail.com Guerrini Benedetta Maso Stefano Pezzella Stefano Scandino Riccardo University of Udine, Italy University of Udine, Italy University of Udine, Italy University of Udine, Italy benedetta.guerrini@libero.it maso.stefano@spes.uniud.it stefanopezzella@hotmail.it riccardoscandino@gmail.com Iacobucci Lorenzo Mastroianni Sofia Pipetone Francesca Maria Antonietta Tenani Giorgia University of Udine, Italy University of Udine, Italy University of Udine, Italy University of Udine, Italy lorimpo@hotmail.it sofiamas23@gmail.com francesca.pipitone97@virgilio.it grtn97@gmail.com Ianna Giulia Minisini Lara Piscopo Giuseppe Tomba Giovanni University of Udine, Italy University of Udine, Italy University of Udine, Italy University of Udine, Italy giuliaianna15@gmail.com lara.minisini96@gmail.com giuseppe.piscopo@live.com giovannitomba@hotmail.it Iovine Michela Minisini Martina Pitassi Anita Toscani Cristoforo University of Udine, Italy University of Udine, Italy University of Udine, Italy University of Udine, Italy iovine.michela@virgilio.it martina.minisini@libero.it pitassi.anita@spes.uniud.it CristoforoToscani8@gmail.com Kocina Chandra Giorgia Molinari Chiara Plosch Daniele Tosolini Damiano University of Udine, Italy University of Udine, Italy University of Udine, Italy University of Udine, Italy kocina.giorgiachandra@spes.uniud.it chia.moli96@gmail.com daniele.plosch@gmail.com tosolini.damiano@spes.uniud.it Lanza Umberto Mondello Alessia Plozner Noemi Totis Cristina University of Udine, Italy University of Udine, Italy University of Udine, Italy University of Udine, Italy lanza.umberto@spes.uniud.it mondelloalessia@gmail.com noemiplozner@hotmail.it cristina.totis@alice.it Lavaroni Jacopo Montanar Valentina Polo Friz Erika Trevisanut Matteo University of Udine, Italy University of Udine, Italy University of Udine, Italy University of Udine, Italy jacopolavaroni@gmail.com alhambra97@hotmail.it 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