Publications Harald Herrmann (last 15 years) - Neuropathologie
←
→
Page content transcription
If your browser does not render page correctly, please read the page content below
Publications Harald Herrmann (last 15 years)
2020
Herrmann H, Cabet E, Chevalier NR, Moosmann J, Schultheis D, Haas J, Schowalter M, Berwanger
C, Weyerer V, Agaimy A, Meder B, Müller OJ, Katus HA, Schlötzer-Schrehardt U, Vicart P,
Ferreiro A, Dittrich S, Clemen CS, Lilienbaum A, Schröder R. (2020) Dual Functional States of
R406W-Desmin Assembly Complexes Cause Cardiomyopathy with Severe Intercalated Disc
Derangement in Humans and in Knock-In Mice. Circulation. Oct 7. doi: 10.1161/
CIRCULATIONAHA.120.050218.
Wu H, Shen Y, Wang D, Herrmann H, Goldman RD, Weitz DA. (2020) Effect of Divalent Cations on the
Structure and Mechanics of Vimentin Intermediate Filaments. Biophys J. 119, 55-64.
Kaus-Drobek M, Mücke N, Szczepanowski RH, Wedig T, Czarnocki-Cieciura M, Polakowska M,
Herrmann H, Wysłouch-Cieszyńska A, Dadlez M. (2020) Vimentin S-glutathionylation at
Cys328 inhibits filament elongation and induces severing of mature filaments in vitro. FEBS J.
Apr 7. doi: 10.1111/febs.15321.
Argente-Escrig H, Schultheis D, Kamm L, Schowalter M, Thiel C, Türk M, Clemen CS, Muelas N,
Castañón MJ, Wiche G, Herrmann H, Vilchez JJ, Schröder R. (2020) Plectin-related
scapuloperoneal myopathy with treatment-responsive myasthenic syndrome. Neuropathol Appl
Neurobiol. Aug 5. doi: 10.1111/nan.12652.
2019
Maitra D, Carter EL, Richardson R, Rittié L, Basrur V, Zhang H, Nesvizhskii AI, Osawa Y, Wolf MW,
Ragsdale SW, Lehnert N, Herrmann H, Omary MB. (2019) Oxygen and Conformation
Dependent Protein Oxidation and Aggregation by Porphyrins in Hepatocytes and Light-Exposed
Cells. Cell Mol Gastroenterol Hepatol. 8, 659-682.
Haug M, Meyer C, Reischl B, Prölß G, Vetter K, Iberl J, Nübler S, Schürmann S, Rupitsch SJ, Heckel
M, Pöschel T, Winter L, Herrmann H, Clemen CS, Schröder R, Friedrich O. (2019) The
MyoRobot technology discloses a premature biomechanical decay of skeletal muscle fiber
bundles derived from R349P desminopathy mice. Sci Rep. 9,10769.
Brennich ME, Vainio U, Wedig T, Bauch S, Herrmann H, Köster S (2019) Mutation-induced alterations
of intra-filament subunit organization in vimentin filaments revealed by SAXS. Soft Matter 15,
1999-2008.
Golde T, Glaser M, Tutmarc C, Elbalasy I, Huster C, Busteros G, Smith DM, Herrmann H, Käs JA,
Schnauß J. (2019) The role of stickiness in the rheology of semiflexible polymers. Soft Matter
15, 4865-4872.
2018
Maaß KK, Rosing F, Ronchi P, Willmund KV, Devens F, Hergt M, Herrmann H, Lichter P, Ernst A (2018)
Altered nuclear envelope structure and proteasome function of micronuclei Experimental Cell
Research 371, 353–363.
Battaglia RA, Delic S, Herrmann H, Snider NT (2018) Vimentin on the move: new developments in cell
migration. F1000Research 7: 1796. https//doi.org/10.12688/f1000.15967.1. Epub 2018 Nov 15.
Review.
1Golde T. Huster C, Glaser M, Händler T, Herrmann H, Käs J, Schnauß J. (2018) Glassy dynamics in
composite biopolymer networks. Soft Matter 14, 7970-7978.
Mücke N, Kämmerer L, Winheim S, Kirmse R, Krieger J, Mildenberger M, Baßler J, Hurt E, Goldmann
WH, Aebi U, Toth K, Langowski J, Herrmann H. (2018) Assembly kinetics of vimentin tetramers
to unit-length filaments: A stopped-flow study. Biophys. J. 114, 2408–2418.
Trogden KP, Battaglia RA, Kabiraj P, Madden VJ, Herrmann H, Snider NT. (2018) An image-based
small molecule screen identifies vimentin as a pharmacologically relevant target of simvastatin
in cancer cells. FASEB J. 32, 2841-2854.
2017
Sharma S, Conover GM, Elliott JL, Der Perng M, Herrmann H, Quinlan RA. (2017) αB-crystallin is a
sensor for assembly intermediates and for the subunit topology of desmin intermediate
filaments. Cell Stress Chaperones 22, 613-626.
Diermeier S, Iberl J, Vetter K, Haug M, Pollmann C, Reischl B, Buttgereit A, Schürmann S, Spörrer M,
Goldmann WH, Fabry B, Elhamine F, Stehle R, Pfitzer G, Winter L, Clemen CS, Herrmann H,
Schröder R, Friedrich O. (2017) Early signs of architectural and biomechanical failure in isolated
myofibers and immortalized myoblasts from desmin-mutant knock-in mice. Sci Rep. 7, 1391.
doi: 10.1038/s41598-017-01485-x.
Premchandar A, Kupniewska A, Bonna A, Faure G, Fraczyk T, Roldan A, Hoffmann B, Faria da Cunha
M, Herrmann H, Lukacs GL, Edelman A, Dadlez M. (2017) New insights into interactions
between the nucleotide-binding domain of CFTR and keratin 8. Protein Sci. 26, 343-354.
Zupancic T, Sersa G, Törmä H, Lane EB, Herrmann H, Komel R, Liovic M. (2017) Keratin gene
mutations influence the keratinocyte response to DNA damage and cytokine induced apoptosis.
Arch Dermatol Res. 309, 587-593.
2016
Hernandez DA, Bennett CM, Dunina-Barkovskaya L, Wedig T, Capetanaki Y, Herrmann H, Conover G
(2016) Nebulette is a powerful cytolinker organizing desmin and actin in mouse hearts. Mol Biol
Cell 27, 3869-3882.
Premchandar A, Mücke N, Poznański J, Wedig T, Kaus-Drobek M, Herrmann H, Dadlez M (2016)
Structural Dynamics of the Vimentin Coiled-Coil Contact Regions involved in Filament Assembly
as revealed by Hydrogen-Deuterium Exchange. J Biol Chem. 291, 24931–24950.
Martin I, Moch M, Neckernuss T, Paschke S, Herrmann H, Marti O (2016) Both monovalent cations and
plectin are potent modulators of mechanical properties of keratin K8/K18 networks. Soft Matter
12, 6964-6974.
West G, Gullmets J, Virtanen L, Li SP, Keinänen A, Shimi T, Mauermann M, Heliö T, Kaartinen M, Ollila
L, Kuusisto J, Eriksson JE, Goldman RD, Herrmann H, Taimen P (2016) Deleterious assembly
of lamin A/C mutant p.S143P causes ER stress in familial dilated cardiomyopathy. J Cell Sci.
129, 2732-2743.
Winter L, Wittig I, Peeva V, Eggers B, Heidler J, Chevessier F, Kley RA, Barkovits K, Strecker V,
Berwanger C, Herrmann H, Marcus K, Kornblum C, Kunz WS, Schröder R, Clemen CS (2016)
Mutant desmin substantially perturbs mitochondrial morphology, function and maintenance in
skeletal muscle tissue. Acta Neuropathol. 132, 453-573.
2Dammann C, Herrmann H, Köster K (2016) Competitive counterion binding regulates the aggregation
onset of charged vimentin intermediate filaments. Isr J Chem. 56, 614-621.
Faure G, Bakouh N, Lourdel S, Odolczyk N, Premchandar A, Servel N, Hatton A, Ostrowski, MK, Xu H,
Saul FA, Moquereau C, Bitam S, Pranke I, Planelles G, Teulon J, Herrmann H, Roldan A,
Zielenkiewicz P, Dadlez M, Lukacs GL, Sermet-Gaudelus I, Ollero M, Corringer PJ, Edelman A
(2016) Rattlesnake Phospholipase A2 increases CFTR-chloride channel current and corrects
∆F508 CFTR dysfunction: impact in Cystic Fibrosis. J Mol Biol. 428, 2898-2915.
Saldanha O, Brennich ME, Burghammer M, Herrmann H, Köster S (2016) The filament forming
reactions of vimentin tetramers studied in a serial-inlet microflow device by small angle x-ray
scattering. Biomicrofluidics 10, 024108.
Mücke N, Winhein S, Merlitz H, Buchholz J, Langowski J, Herrmann H (2016) In vitro Assembly Kinetics
of Cytoplasmic Intermediate Filaments: A Correlative Monte Carlo Simulation Study. PLoS One
11, e0157451.
Behrens J, Solga R, Ziemann A, Rastetter RH, Berwanger C, Herrmann H, Noegel AA, Clemen CS
(2016) Coronin 1C-free primary mouse fibroblasts exhibit robust rearrangements in the
orientation of actin filaments, microtubules and intermediate filaments. Eur J Cell Biol. 95, 239-
251.
Herrmann H, Aebi U (2016) Intermediate Filaments: Structure and Assembly. Cold Spring Harb
Perspect Biol. 8, a018242. Review.
2015
Zwerger M, Roschitzki-Voser H, Zbinden R, Denais C, Herrmann H, Lammerding J, Grutter MG,
Medalia O (2015) Altering lamina assembly reveals lamina-dependent and -independent
functions for A-type lamins. J Cell Sci. 128, 3607-3620.
Premchandar A, Kupniewska A, Tarnowski K, Mücke N, Mauermann M, Kaus-Drobek M, Edelman A,
Herrmann H, Dadlez M. (2015) Analysis of distinct molecular assembly complexes of keratin
K8 and K18 by hydrogen-deuterium exchange. J Struct Biol. 192, 426-440.
Hemonnot C, Mauermann M, Herrmann H, Koester S (2015) The assembly of simple epithelial keratin
filaments: Deciphering the ion-dependence in filament organization. BioMacromolecules 16,
3313–3321.
Martin I, Leitner A, Walther P, Herrmann H, Marti O (2015) Model-based analysis of keratin intermediate
filament assembly. JPhysD, 48 375401 (11pp)
Kornreich M, Malka-Gibor E, Laser-Azogui A, Doron O, Herrmann H, Beck R (2015) Composite
bottlebrush mechanics: α-internexin fine-tunes neurofilament network properties. Soft Matter
11, 5839-5849.
Damiano JA, Afawi Z, Bahlo M, Mauermann M, Misk A, Arsov T, Oliver KL, Dahl HH, Shearer AE, Smith
RJ, Hall NE, Mahmood K, Leventer RJ, Scheffer IE, Muona M, Lehesjoki AE, Korczyn AD,
Herrmann H, Berkovic SF, Hildebrand MS (2015) Mutation of the nuclear lamin gene LMNB2
in progressive myoclonus epilepsy with early ataxia. Hum Mol Genet. 24, 4483-4490.
Alastalo TP, West G, Li SP, Keinänen A, Helenius M, Tyni T, Lapatto R, Turanlahti M, Heikkilä P,
Kääriäinen H, Laakso M, Mauermann M, Herrmann H, Pihkala J, Taimen P (2015) LMNA
Mutation c.917T>G (p.L306R) Leads to Deleterious Hyper-Assembly of Lamin A/C and
Associates with Severe Right Ventricular Cardiomyopathy and Premature Aging. Hum Mutat.
36, 694-703.
3Clemen CS, Stöckigt F, Strucksberg KH, Chevessier F, Winter L, Schütz J, Bauer R, Thorweihe JM,
Wenzel D, Schneider-Stock R, Schlötzer-Schrehardt U, Rasche V, Krsmanovic P, Katus HA,
Rottbauer W, Just S, Müller O, Friedrich O, Meyer R, Herrmann H, Schrickel JW, Schröder R
(2015) The toxic effect of R350P mutant desmin in striated muscle of man and mouse. Acta
Neuropathol. 129, 297-315.
Lowery J, Kuczmarski ER, Herrmann H, Goldman RD (2015) Intermediate Filaments Play a Pivotal
Role in Regulating Cell Architecture and Function. J Biol Chem. 290, 17145-17153.
Köster S, Weitz DA, Goldman RD, Aebi U, Herrmann H (2015) Intermediate filament mechanics in vitro
and in the cell: from coiled coils to filaments, fibers and networks. Curr. Op. Cell Biol. 32, 82-91.
2014
Jung H-J, Tatar A, Tu Y, Nobumori C, Yang SH, Goulbourne CN, Herrmann H, Fong LG, Young SG
(2014) An absence of nuclear lamins in keratinocytes leads to ichthyosis, defective epidermal
barrier function, and intrusion of nuclear membranes and endoplasmic reticulum into the nuclear
chromatin. Mol Cell Biol. 34, 4534-4544.
Nöding B, Herrmann H, Köster S (2014) Direct Observation of Subunit Exchange Along Mature
Vimentin Intermediate Filaments. Biophys J. 107, 1-8.
Ramm B, Stigler J, Hinczewski M, Thirumalai D, Herrmann H, Woehlke G, Rief M (2014) Sequence-
resolved free energy profiles of stress-bearing vimentin intermediate filaments. Proc. Natl. Acad.
Sci. USA 111, 11359-11364.
Pawelzyk P, Mücke N, Herrmann H, Willenbacher N (2014) Attractive interactions among intermediate
filaments determine network mechanics in vitro. PLoS One 9, e93194.
Robert A, Herrmann H, Davidson MW, Gelfand VI (2014) Microtubule-dependent transport of vimentin
filament precursors is regulated by actin and the concerted action of Rho- and p21-activated
kinases. FASEB J. 28, 2879-2890.
Brennich M, Bauch S, Vainio U, Wedig T, Herrmann H, Köster S (2014) Impact of ion valency on the
assembly of vimentin studied by quantitative small angle X-ray scattering. Soft Matter 10, 2059-
68.
Gregor M, Osmanagic-Myers S, Burgstaller G, Wolfram M, Fischer I, Walko G, Resch GP, Jörgl A,
Herrmann H, Wiche G (2014) Mechanosensing through focal adhesion-anchored intermediate
filaments. FASEB J. 28, 715-729.
2013
Odolczyk N, Fritsch J, Norez C, Servel N, Faria da Cunha M, Bitam S, Kupniewska A, Wiszniewski L,
Colas J, Tarnowski K, Tondelier D, Roldan A, Saussereau EL, Melin-Heschel P, Wieczorek G,
Lukacs G, Dadlez M, Faure G, Herrmann H, Ollero M, Becq F, Zielenkiewicz P, Edelman (2013)
Discovery of novel ∆F508-CFTR correctors by targeting the specific conformation of nucleotide
binding domain. EMBO Mol Med. 5, 1-18.
Kayser J, Haslbeck M, Dempfle L, Krause M, Grashoff C, Buchner J, Herrmann H, Bausch AR (2013)
The small heat shock protein Hsp27 affects assembly dynamics and structure of keratin
intermediate filament networks. Biophys J. 105, 1778-1785.
Pawelzyk P, Herrmann H, Willenbacher N (2013) Mechanics of intermediate filament networks
assembled from keratins K8 and K18. Soft Matter 9, 8871-8880.
4Singla A, Griggs NW, Kwan R, Snider NT, Maitra D, Ernst SA, Herrmann H, Omary MB (2013) Lamin
aggregation is an early sensor of porphyria-induced liver injury. J Cell Sci., 126, 3105-3112.
Rowat AC, Jaalouk DE, Zwerger M, Ung WL, Eydelnant IA, Olins DE, Olins AL, Herrmann H, Weitz
DA, Lammerding J. (2013) Nuclear envelope composition determines the ability of neutrophil-
type cells to passage through micron-scale constrictions. J Biol. Chem. 288, 8610-8618.
Zwerger M, Jaalouk DE, Lombardi ML, Isermann P, Mauermann M, Dialynas G, Herrmann H, Wallrath
LL, Lammerding J. (2013) Myopathic lamin mutations impair nuclear stability in cells and tissue
and disrupt nucleo-cytoskeletal coupling. Hum Mol Genet. 22, 2335-2349.
Baker LK, Gillis DC, Sharma S, Ambrus A, Herrmann H, Conover GM. (2013) Nebulin binding impedes
mutant desmin filament assembly. Mol Biol Cell. 24, 1918-1932.
Solovei I, Wang AS, Thanisch K, Schmidt CS, Krebs S, Zwerger M, Cohen TV, Devys D, Foisner R,
Peichl L, Herrmann H, Blum H, Engelkamp D, Stewart CL, Leonhardt H, Joffe B. (2013) LBR
and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate
differentiation. Cell 152, 584-598.
Clemen CS, Herrmann H, Strelkov SV, Schröder R. (2013) Desminopathies: pathology and
mechanisms. Acta Neuropathol. 125, 47-75. Review.
Herrmann H (2013) Nuclear architecture and dynamics: chromatin, epigenetics, genomics: Review of
Genome Organization and Function in the Cell Nucleus: Edited by Karsten Rippe. Nucleus 4,
85 – 88. Review.
2012
Chernyatina AA, Nicolet S, Aebi U, Herrmann H, Strelkov SV. (2012) Atomic structure of the vimentin
central α-helical domain and its implications for intermediate filament assembly. Proc. Natl.
Acad. Sci. U S A 109, 13620-13625.
Leitner A, Paust T, Marti O, Walther P, Herrmann H, Beil M. (2012) Properties of intermediate filament
networks assembled from keratin 8 and 18 in the presence of Mg²+. Biophys J. 103,195-201.
Colas J, Faure G, Saussereau E, Trudel S, Rabeh WM, Bitam S, Guerrera IC, Fritsch J, Sermet-
Gaudelus I, Davezac N, Brouillard F, Lukacs GL, Herrmann H, Ollero M, Edelman A. (2012)
Disruption of cytokeratin-8 interaction with F508del-CFTR corrects its functional defect. Hum.
Mol. Genet. 21, 623-34.
Lichtenstern T, Mücke N, Aebi U, Mauermann M, Herrmann, H (2012) Complex formation and kinetics
of filament assembly exhibited by the simple epithelial keratins K8 and K18. J. Struct. Biol. 177,
54-62.
Kayser J, Grabmayr H, Harasim M, Herrmann H, Bausch AR (2012) Formation of keratin bundle
networks. Soft Matter 8, 8873-8879.
Grin B, Mahammad S, Wedig T, Cleland MM, Tsai L, Herrmann H, Goldman R.D. (2012) Withaferin A
alters intermediate filament organization, cell shape and behavior. PLoS One 7, e39065.
Bargagna-Mohan P, Paranthan RR, Hamza A, Zhan CG, Lee DM, Kim KB, Lau DL, Srinivasan C,
Nakayama K, Nakayama KI, Herrmann H, Mohan R. (2012) Corneal antifibrotic switch identified
in genetic and pharmacological deficiency of vimentin. J. Biol. Chem. 287, 989-1006.
52011
Kolb T, Maass K, Hergt M, Aebi U, Herrmann H. (2011) Lamin A and lamin C form homodimers and
coexist in higher complex forms both in the nucleoplasmic fraction and in the lamina of cultured
human cells. Nucleus 2, 425-433.
Winheim S, Hieb AR, Silbermann M, Surmann EM, Wedig T, Herrmann H, Langowski J, Mücke N.
(2011) Deconstructing the late phase of vimentin assembly by total internal reflection
fluorescence microscopy (TIRFM). PLoS One. 6(4), e19202.
Plodinec M, Loparic M, Suetterlin R, Herrmann H, Aebi U, Schoenenberger CA. (2011) Interfering with
the vimentin intermediate filament system modulates the nanomechanical properties of rat
fibroblasts. J. Struct. Biol. 174, 476-484.
Cabeen MT, Herrmann H, Jacobs-Wagner C. (2011) The domain organization of the bacterial
intermediate filament-like protein crescentin is important for assembly and function.
Cytoskeleton 68, 205-219.
Kapinos L.E., Burkhard P, Herrmann H, Aebi U, Strelkov SV. (2011) Simultaneous formation of right-
and left-handed anti-parallel coiled-coil interfaces by a coil2 fragment of human lamin A. J. Mol.
Biol. 408, 135-146.
Helfand BT, Mendez MG, Murthy SN, Shumaker DK, Grin B, Mahammad S, Aebi U, Wedig T, Wu YI,
Hahn KM, Inagaki M, Herrmann H, Goldman RD. (2011) Vimentin organization modulates the
formation of lamellipodia. Mol. Biol. Cell 22,1274-1289.
Brennich ME, Nolting JF, Dammann C, Nöding B, Bauch S, Herrmann H, Pfohl T, Köster S (2011)
Dynamics of intermediate filament assembly followed in micro-flow by small angle X-ray
scattering. Lab Chip 11, 708-716.
Snider NT, Weerasinghe SV, Iñiguez-Lluhí JA, Herrmann H, Omary MB (2011) Keratin
hypersumoylation alters filament dynamics and is a marker for human liver disease and keratin
mutation. J. Biol. Chem. 286, 2273-2284.
Meshorer E, Herrmann H, Raška I (2011) Nuclear visions enhanced: chromatin structure, organization
and dynamics. EMBO Rep. 12, 748-750. Review.
Herrmann H, Strelkov SV. (2011) History and phylogeny of intermediate filaments: now in insects. BMC
Biol. 9:16. Review.
2010
Köster S, Lin Y-C, Herrmann H, Weitz DA (2010) Nanomechanics of vimentin intermediate filament
networks. Soft Matter 6, 1910–1914.
Lin YC, Broedersz CP, Rowat AC, Wedig T, Herrmann H, Mackintosh FC, Weitz DA. (2010) Divalent
cations crosslink vimentin intermediate filament tail domains to regulate network mechanics. J.
Mol. Biol. 399, 637-644.
Lin YC, Yao NY, Broedersz CP, Herrmann H, Mackintosh FC, Weitz DA. (2010) Origins of elasticity in
intermediate filament networks. Phys. Rev. Lett. 104, 058101.
Nicolet S, Herrmann H, Aebi U and Strelkov SV. (2010) Atomic structure of vimentin coil 2. J. Struct.
Biol. 170, 369-376.
Bär H, Schopferer M, Sharma S, Hochstein B, Mücke N, Herrmann H and Willenbacher, N. (2010)
Mutations in desmin's carboxy-terminal "tail" domain severely modify filament and network
mechanics. J. Mol. Biol. 397, 1188-1198.
6Olins AL, Ernst A, Zwerger M, Herrmann H, Olins DE. (2010) An in vitro model for Pelger-Huët anomaly:
stable knockdown of lamin B receptor in HL-60 cells. Nucleus 1, 506-512.
Kapinos LE, Schumacher J, Mücke N, Machaidze G, Burkhard P, Aebi U, Strelkov SV and Herrmann
H. (2010) Characterization of the head-to-tail overlap complexes formed by human lamin A, B1
and B2 "half-minilamin" dimers. J. Mol. Biol. 396, 719-731.
Zwerger M, Kolb T, Richter K, Karakesisoglou I and Herrmann H. (2010) Induction of a massive
endoplasmic reticulum and perinuclear space expansion by expression of lamin B receptor
mutants and the related sterol reductases TM7SF2 and DHCR7. Mol. Biol. Cell 21, 354-368.
Herrmann H, Zwerger M. (2010) The danger of "multi-tasking": LBR out of control. Nucleus 1, 319-324.
Review.
2009
Ben-Harush, K., N. Wiesel, D. Frenkiel-Krispin, D. Moeller, E. Soreq, U. Aebi, H. Herrmann, Y.
Gruenbaum, and O. Medalia (2009) The supramolecular organization of the C. elegans nuclear
lamin filament. J. Mol. Biol. 386, 1392-1402.
Georgakopoulou, S., D. Möller, N. Sachs, H. Herrmann, and U. Aebi (2009) Near-UV circular dichroism
reveals structural transitions of vimentin subunits during intermediate filament assembly. J. Mol.
Biol. 386, 544-553.
Meier M, Padilla GP, Herrmann H, Wedig T, Hergt M, Patel TR, Stetefeld J, Aebi U, Burkhard P (2009)
Vimentin coil 1A-A molecular switch involved in the initiation of filament elongation. J. Mol. Biol.
390, 245-261.
Müller, M., S.S. Bhattacharya, T. Moore, Q. Prescott, T. Wedig, H. Herrmann, and T.M. Magin (2009)
Dominant cataract formation in association with a vimentin assembly disrupting mutation. Hum.
Mol. Genet. 18, 1052-1057.
Olins, A.L., T.V. Hoang, M. Zwerger, H. Herrmann, H. Zentgraf, A.A. Noegel, I. Karakesisoglou, D.
Hodzic, and D.E. Olins (2009) The LINC-less granulocyte nucleus. Eur. J. Cell Biol. 88, 203-
214.
Schopferer, M., H. Bär, B. Hochstein, S. Sharma, N. Mücke, H. Herrmann, and N. Willenbacher (2009)
Desmin and vimentin intermediate filament networks: their viscoelastic properties investigated
by mechanical rheometry. J. Mol. Biol. 388, 133-143.
Portet, S., N. Mücke, R. Kirmse, J. Langowski, M. Beil, and H. Herrmann (2009) Vimentin intermediate
filament formation: In vitro measurement and mathematical modeling of the filament length
distribution during assembly. Langmuir 25, 8817-8823.
Mücke N, Klenin K, Kirmse R, Bussiek M, Herrmann H, Hafner M, Langowski J (2009) Flilamentous
biopolymers on surfaces: atomic force microscopy images compared with Brownian dynamics
simulation of filament deposition. PLoS One 4(11):e7756.
Chang, L., K. Barlan, Y.-H. Chou, B. Grin, M. Lakonishok, A.S. Serpinskaya. D.K. Shumaker, H.
Herrmann, V.I. Gelfand, and R.D. Goldman (2009) The dynamic properties of intermediate
filaments during organelle transport. J. Cell Sci. 122, 2914-2923.
Sharma, S., Mücke, N. Katus, H.A., Herrmann, H. and Bär, H. (2009) Disease mutations in the non-α-
helical amino-terminal domain of the intermediate filament protein desmin severely impair
filament assembly and network formation. J. Mol. Med. 87, 1207-1219.
7Taimen, P., Pfleghaar, K., Shimi, T., Möller, D., Ben-Harush, K., Erdos, M.R., Adam, S.A., Herrmann,
H., Medalia, O., Collins, F.S., Goldman, A.E., and Goldman, R.D. (2009) A progeria mutation
reveals functions for lamin A in nuclear assembly, architecture, and chromosome organization.
Proc. Natl. Acad. Sci. U S A., 106, 20788-20793.
Herrmann, H., Strelkov S.V., Burkhard P., and Aebi U. (2009) Intermediate filaments: primary
determinants of cell architecture and plasticity. J. Clin. Invest. 119, 1772-1783. Review.
2008
Bornheim, R., Müller, M., Reuter, U., Herrmann, H., Bussow, H., and Magin, T. M. (2008). A dominant
vimentin mutant upregulates Hsp70 and the activity of the ubiquitin-proteasome system, and
causes posterior cataracts in transgenic mice. J. Cell Sci. 121, 3737-3746.
Geiger, S. K., Bär, H., Ehlermann, P., Wälde, S., Rutschow, D., Zeller, R., Ivandic, B. T., Zentgraf, H.,
Katus, H. A., Herrmann, H., and Weichenhan, D. (2008) Incomplete nonsense-mediated decay
of mutant lamin A/C mRNA provokes dilated cardiomyopathy and ventricular tachycardia. J.
Mol. Med. 86, 281-289.
Kreplak, L., Herrmann, H., and Aebi, U. (2008) Tensile properties of single desmin intermediate
filaments. Biophys. J. 94, 2790-2799.
Olins, A. L., Zwerger, M., Herrmann, H., Zentgraf, H., Simon, A. J., Monestier, M., and Olins, D. E.
(2008) The human granulocyte nucleus: Unusual nuclear envelope and heterochromatin
composition. Eur. J. Cell Biol. 87, 279-290.
Wiesel, N., Mattout, A., Melcer, S., Melamed-Book, N., Herrmann, H., Medalia, O., Aebi, U., and
Gruenbaum, Y. (2008) Laminopathic mutations interfere with the assembly, localization, and
dynamics of nuclear lamins. Proc. Natl. Acad. Sci. USA 105, 180-185.
Zwerger, M., Herrmann, H., Gaines, P., Olins, A. L., and Olins, D. E. (2008) Granulocytic nuclear
differentiation of lamin B receptor-deficient mouse EPRO cells. Exp. Hematol. 36, 977-987.
Brauksiepe, B., Mujica, A.O., Herrmann, H. and Schmidt E.R. (2008) The Serine/threonine kinase Stk33
exhibits autophosphorylation and phosphorylates the intermediate filament protein vimentin.
BMC Biochem. 9, 25.
Kreplak, L., Richter, K., Aebi, U., and Herrmann, H. (2008) Electron microscopy of intermediate
filaments: Teaming up with atomic force and confocal laser scanning microscopy. Meth. Cell
Biol. 88, 273-297.
Rowat, A.C., Lammerding, J., Herrmann, H., and Aebi, U. (2008) Towards an integrated understanding
of the structure and mechanics of the cell nucleus. Bioessays 30, 226-236. Review.
Schmitz, M. L. and Herrmann, H. (2008) Functional architecture of the cell nucleus. Biochim. Biophys.
Acta-Mol. Cell Res. 1783, 2041-2043.
2007
Bär, H., Mücke, N., Katus, H.A., Aebi, U. and Herrmann, H. (2007) Assembly defects of disease mutants
carrying small deletions in the coiled-coil domain are rescued by wild type desmin. J. Struct.
Biol. 158, 107-115.
Bär, H., Goudeau, B., Wälde, S., Casteras-Simon, M., Mücke, N., Shatunov, A., Goldberg, Y.P., Clarke,
C., Holton, J.L., Eymard, B., Katus, H.A., Fardeau, M., Goldfarb, L., Vicart, P. and Herrmann,
H. (2007) Conspicuous involvement of desmin tail mutations in diverse cardiomyopathies. Hum.
Mut. 28, 374-386.
8Goldie, K.N., Wedig, T., Mitra, A., Aebi, U., Herrmann, H. and Hoenger, A. (2007) Dissecting the 3-D
structure of vimentin intermediate filaments by cryo-electron tomography. J. Struct. Biol. 158,
378-385.
Huizinga, R., Heijmans, N., Schubert, P., Gschmeissner, S., t’Hart, B.A., Herrmann, H. and Amor, S.
(2007) Autoimmunity to neurofilament-light induces spasticity and paralysis associated with
axonal degeneration in Biozzi ABH mice. J. Neuropathol. Exp. Neurol. 66, 295-304.
Kirmse, R., Portet, S., Mücke, N., Aebi, U., Herrmann, H. and Langowski, J. (2007) The kinetics of
intermediate filament assembly: Evidence for unit-length and filament end-to-end annealing as
a mechanism for longitudinal growth of filaments. J. Biol. Chem. 282, 18563-18572.
Hesse, M., Grund, C., Herrmann, H., Bröhl, D., Franz, T., Omary, M.B. and Magin, T.M. (2007) A
mutation of keratin 18 within the coil 1A consensus motif causes widespread keratin aggregation
but cell type-restricted lethality in mice. Exp. Cell Res. 313, 3127-3140.
Bridger J.M., Foeger N., Kill I.R., Herrmann, H. (2007) The nuclear lamina. Both a structural framework
and a platform for genome organization. FEBS J. 274, 1354-1361. Review.
Herrmann, H., Bär, H., Kreplak, L., Strelkov, S.V. and Aebi, U. (2007) Intermediate filaments: from cell
architecture to nanomechanics. Nat. Rev. Mol. Cell. Biol. 8, 562-573. Review.
2006
Schietke, R., Bröhl, D., Wedig, T., Mücke, N., Herrmann, H. and Magin, T.M. (2006) Dominant mutations
in vimentin prevent assembly in vitro and disrupt the cytoskeleton in fibroblasts. Eur. J. Cell Biol.
85, 1-10.
Foeger, N., Wiesel, N., Lotsch, D., Mücke, N., Kreplak, L., Aebi, U., Gruenbaum, Y. and Herrmann H.
(2006) Solubility properties and specific assembly pathways of the B-type lamin from
Caenorhabditis elegans. J. Struct. Biol. 155, 340-350.
Zhou, Q., Cadrin, M., Herrmann, H., Chen, C.H., Chalkley, R.J., Burlingame, A.L. and Omary, M.B.
(2006) Keratin 20 serine 13 phosphorylation is a stress and intestinal goblet cell marker. J Biol
Chem. 281, 16453-16461.
Bär, H., Kostareva, A., Sjoberg, G., Sejersen, T., Katus, H.A. and Herrmann, H. (2006) Forced
expression of desmin and desmin mutants in cultured cells: impact of myopathic missense
mutations in the central coiled-coil domain on network formation. Exp Cell Res. 312, 1554-1565.
Bär, H., Mücke, N., Ringler, P., Müller, S.A., Kreplak, L. Katus, H.A., Aebi, U. and Herrmann, H. (2006)
Impact of diesease mutations on the desmin filament assembly process. J Mol Biol. 360, 1031-
1040.
Sokolova, A.V., Kreplak, L., Wedig, T., Mücke, N., Svergun, D.I., Herrmann, H., Aebi,U. and Strelkov,
S.V. (2006) Monitoring intermediate filament assembly by small-angle x-ray scattering reveals
the molecular architecture of assembly intermediates. Proc Natl Acad Sci 103,16206-16211.
Schumacher J, Reichenzeller M, Kempf T, Schnölzer M and Herrmann H (2006) Identification of a novel,
highly variable amino-terminal amino acid sequence element in the nuclear intermediate
filament protein lamin B2 from higher vertebrates. FEBS Lett. 580, 6211-6216.
9You can also read
