Public Health Update with the Indiana Department of Health - February 2, 2022

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Public Health Update with the Indiana Department of Health - February 2, 2022
Public Health Update with the Indiana
Department of Health

February 2, 2022
Public Health Update with the Indiana Department of Health - February 2, 2022
Agenda
    • Opening Remarks
    • Housekeeping
    • Presentation
    • Q&A
    • Closing Remarks

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Public Health Update with the Indiana Department of Health - February 2, 2022
Who We Are
    Qsource has more than 45
    years of experience working
    with with healthcare providers,
    Medicare and Medicaid.
    Currently operate in 11 states
    overseeing ESRD, EQRO and
    QIO activities.
    Serves as the Medicare Quality
    Innovation Network-Quality
    Improvement Organization
    (QIN-QIO) for Indiana.

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Public Health Update with the Indiana Department of Health - February 2, 2022
Housekeeping Items: Chat
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Public Health Update with the Indiana Department of Health - February 2, 2022
Polling Question
    In which setting do you work?
       A.   Long Term Care
       B.   Hospital
       C.   Home Health
       D.   Community-Based Organization
       E.   Other

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Public Health Update with the Indiana Department of Health - February 2, 2022
PUBLIC HEALTH
UPDATES

PAM PONTONES, MA
DEPUTY STATE HEALTH
COMMISSIONER
STATE EPIDEMIOLOGIST

02/02/2022
Public Health Update with the Indiana Department of Health - February 2, 2022
Omicron is different
from previous variants
Public Health Update with the Indiana Department of Health - February 2, 2022
CDC MMWR: Vaccine vs Unvaccinated

• Using over eight months of data in 2021 from 25 states, investigators reviewed
  changes in rates of COVID-19 cases (April 4–December 25, 2021) and associated
  deaths (April 4–December 4, 2021) by vaccination status, including receipt of
  boosters. Investigators assessed rates before and during the Delta period as well as
  during the emergence of Omicron.
• In 2021, compared with fully vaccinated people overall (received a primary series),
  unvaccinated people had
  o   14 times the risk of infection pre-Delta (April–May)
  o   9 times the risk of infection as Delta emerged (June)
  o   5 times the risk of infection during Delta’s predominance (July–November)
  o   More than 15 times the risk of death before and after Delta emerged (relatively stable
      during July–November)

                          https://www.cdc.gov/mmwr/volumes/71/wr/mm7104e2.htm?s_cid=mm7104e2_e&ACSTrackingID=USCDC_921-
                                               DM73911&ACSTrackingLabel=MMWR%20Early%20Release%20-
                                   %20Vol.%2071%2C%20January%2021%2C%202022&deliveryName=USCDC_921-DM73911 -
Public Health Update with the Indiana Department of Health - February 2, 2022
Rates of COVID-19 Cases and Deaths by Vaccination Status

      https://covid.cdc.gov/covid-data-tracker/#rates-by-vaccine-status
Public Health Update with the Indiana Department of Health - February 2, 2022
CDC MMWR: Vaccine and boosted vs Unvaccinated during Delta
• Comparing unvaccinated people and fully vaccinated people by receipt of
  booster doses during the period of Delta variant predominance (October–
  November 2021)
• Compared with fully vaccinated people without a booster, unvaccinated
  adults had
  o 4 times the risk of infection with the virus that causes COVID-19
  o 13 times the risk of COVID-19-associated deaths
• Compared with fully vaccinated adults with a booster, unvaccinated adults
  had
o 14 times the risk of infection with the virus that causes COVID-19
o More than 50 times the risk of COVID-19-associated deaths

                     https://www.cdc.gov/mmwr/volumes/71/wr/mm7104e2.htm?s_cid=mm7104e2_e&ACSTrackingID=USCDC_921-
                                          DM73911&ACSTrackingLabel=MMWR%20Early%20Release%20-
                               %20Vol.%2071%2C%20January%2021%2C%202022&deliveryName=USCDC_921-DM73911
CDC MMWR: Vaccine and boosted vs Unvaccinated during Omicron
Comparing unvaccinated people and fully vaccinated people by
receipt of booster doses during the period of Omicron variant
emergence (December 2021)
 • Compared with fully vaccinated adults with a booster, unvaccinated adults
   had 5 times the risk of infection with the virus that causes COVID-19
 • Compared with fully vaccinated people without a booster, unvaccinated
   adults had 3 times the risk of infection with the virus that causes COVID-19

                    https://www.cdc.gov/mmwr/volumes/71/wr/mm7104e2.htm?s_cid=mm7104e2_e&ACSTrackingID=USCDC_921-
                                         DM73911&ACSTrackingLabel=MMWR%20Early%20Release%20-
                              %20Vol.%2071%2C%20January%2021%2C%202022&deliveryName=USCDC_921-DM73911
Moderna Vaccine Gets Full FDA Approval

• U.S. Food and Drug Administration gave full approval
  Jan. 31 to Moderna vaccine for 18 and older
• New vaccine is branded as Spikevax
• Same formulation as the EUA Moderna
• Used as primary series of two doses
• Full approval is another signal of confidence in the
  vaccine’s safety and efficacy

                 https://www.fda.gov/news-events/press-
            announcements/coronavirus-covid-19-update-fda-
           takes-key-action-approving-second-covid-19-vaccine
Novavax Submits Request to FDA

• Protein-based vaccine engineered from the genetic sequence of
  the first strain of SARS-CoV-2
• Ages 18 and older
• The vaccination regimen calls for two 0.5 ml doses (5 mcg antigen
  and 50 mcg Matrix-M adjuvant) given intramuscularly 21 days
  apart.
• Stored at 2°- 8° Celsius
• Studying third dose and ages 12-17
• More information on trials published in New England Journal of
  Medicine:
 https://www.nejm.org/doi/full/10.1056/NEJMoa2116185?query=featured_home

              https://ir.novavax.com/2022-01-31-Novavax-Submits-Request-
              to-the-U-S-FDA-for-Emergency-Use-Authorization-of-COVID-
                                       19-Vaccine
Pfizer Submits Request to FDA

• Submitted request to FDA for EUA for 2-dose vaccine for those 6 months-
COVID and Influenza

Week ending            ILI percentage from   ILI percentage from   Percentage of flu
                       sentinel              syndromic             positive specimens
                                                                   tested at IDOH
December 11            2.25%                 2.28%                 17% (5+ of 29
                                                                   specimens)
December 18            2.57%                 2.43%                 31% (9+ of
                                                                   29 specimens)
December 25            3.05%                 3.00%                 0% (8 specimens)
January 1              3.24%                 3.32%                 44% (4+ of 9 specimens)
January 8              2.81%                 2.76%                 25% (1+ of 4 specimens)
January 15             2.65%                 2.62%                 0% (8 specimens)
January 22             2.07%                 2.04%                 0% (4 neg, 1 unsat)
              https://www.in.gov/health/erc/infectious-disease-epidemiology/diseases-
              and-conditions-resource-page/weekly-influenza-reports
Pneumonia Vaccines

• Vaccines help prevent pneumococcal disease, which is any type of illness caused by Streptococcus
  pneumoniae bacteria
• Two kinds of pneumococcal vaccines available in the United States:
  • Pneumococcal conjugate vaccines (PCV13, PCV15, and PCV20)
  • Pneumococcal polysaccharide vaccine (PPSV23)
• You can get a COVID-19 vaccine and other vaccines, including a flu vaccine, at the same visit
• Experience with other vaccines has shown that the way our bodies develop protection, known as an
  immune response, and possible side effects after getting vaccinated are generally the same when given
  alone or with other vaccines. Learn more about the timing of other vaccines

                  Frequently Asked Questions about COVID-19
                  Vaccination | CDC

                                                                                                          16
Latest Guidance

      Use of 15-Valent Pneumococcal Conjugate Vaccine and 20-
      Valent Pneumococcal Conjugate Vaccine Among U.S. Adults:
      Updated Recommendations of the Advisory Committee on
      Immunization Practices — United States, 2022 | MMWR
                                                                 17
      (cdc.gov)
Summary of Recommendations

• CDC recommends PCV13 for:
 • All babies and children younger than 2 years old
 • Children 2 through 18 years old with certain medical conditions
• CDC recommends PCV15 or PCV20 for:
 • Adults 65 years or older
 • Adults 19 through 64 years old with certain medical conditions or risk factors
• CDC recommends PPSV23 for:
 • Children 2 through 18 years old with certain medical conditions
 • Adults 19 years or older who get PCV15

                          Pneumococcal Vaccination | CDC

                                                                                    18
Other Updates and Numbers
Case Trend

Cases during the
omicron surge
continue to
trend in the
younger age
groups. Those 0-
39 make up
about 60% of all
current cases.
Case Trend by District
Cases Per Capita in Surrounding States
Cases by Type
Therapeutics Map Updated

      https://www.coronavirus.in.gov/covid-19-treatment-information/
Vaccinations by Week
County Metrics

Last week:       This week:
Hospital Census

     Indiana’s COVID hospital census is still high but appears to have
   peaked and is dropping. As of Jan. 27, Indiana reported 2,898 COVID
   patients in the hospital. This is down from the omicron peak of 3,506
                 and the first time below 3,000 in a month.
Hospitalizations by Age Group
Questions?

Pam Pontones, MA        Shireesha
Deputy Health           Vuppalanchi, MD
Commissioner            Medical Director
State Epidemiologist    Long-Term Care
Indiana Department of   Division
Health                  Indiana Department of
ppontones@isdh.in.go    Health
v                       svuppalanchi@isdh.in.
                        gov
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     This material was prepared by Qsource, a/an Network of Quality Improvement and Innovation Contractors under contract with the Centers for
     Medicare & Medicaid Services (CMS), an agency of the U.S. Department of Health and Human Services (HHS). Views expressed in this
31   material do not necessarily reflect the official views or policy of CMS or HHS, and any reference to a specific product or entity herein does not
     constitute endorsement of that product or entity by CMS or HHS. 22.QIO.CLIN6.01.004
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