Proudly Exploring for Uranium in Saskatchewan's North - TSXV: ISO OTC: ISENF

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Proudly Exploring for Uranium in Saskatchewan's North - TSXV: ISO OTC: ISENF
TSXV: ISO
                      OTC: ISENF

Proudly Exploring for Uranium
  in Saskatchewan’s North

                    June 2022
Proudly Exploring for Uranium in Saskatchewan's North - TSXV: ISO OTC: ISENF
Disclaimer
    Information Contained In This Presentation

       This presentation is a summary description of IsoEnergy Ltd. (“IsoEnergy” or the “Company”) and its business and does                 Forward-looking information and statements also involve known and unknown risks and uncertainties and other factors,
       not purport to be complete. This presentation is not, and in no circumstances is it to be construed as, a prospectus, an              which may cause actual events or results in future periods to differ materially from any projections of future events or
       advertisement, or a public offering of securities. No securities regulatory authority or similar authority has reviewed or in         results expressed or implied by such forward-looking information or statements, including, among others: negative
       any way passed upon the document or the merits of the Company’s securities and any representation to the contrary is                  operating cash flow and dependence on third party financing, uncertainty of additional financing, no known mineral
       an offence.                                                                                                                           reserves or resources, the limited operating history of the Company, the influence of a large shareholder, alternative
                                                                                                                                             sources of energy and uranium prices, aboriginal title and consultation issues, reliance on key management and other
       Except where otherwise indicated, the information contained in this presentation has been prepared by IsoEnergy and                   personnel, actual results of exploration activities being different than anticipated, changes in exploration programs based
       there is no representation or warranty by IsoEnergy or any other person as to the accuracy or completeness of the                     upon results, availability of third party contractors, availability of equipment and supplies, failure of equipment to
       information set forth herein. Except as otherwise stated, information included in this presentation is given as of the date           operate as anticipated; accidents, effects of weather and other natural phenomena and other risks associated with the
       hereof. The delivery of this presentation shall not imply that the information herein is correct as of any date after the date        mineral exploration industry, environmental risks, changes in laws and regulations, community relations and delays in
       hereof.                                                                                                                               obtaining governmental or other approvals.

       This presentation shall not constitute an offer to sell or a solicitation of any offer to buy any securities, nor shall there be      Although the Company has attempted to identify important factors that could cause actual results to differ materially
       any sale of any securities in any jurisdiction in which such offer, solicitation or sale would be unlawful. The securities            from those contained in the forward-looking information or implied by forward-looking information, there may be other
       referenced herein have not been, nor will they be, registered under the United States Securities Act of 1933, as amended              factors that cause results not to be as anticipated, estimated or intended. There can be no assurance that forward-looking
       (the “U.S. Securities Act”), and such securities may not be offered or sold within the United States absent registration              information and statements will prove to be accurate, as actual results and future events could differ materially from
       under the U.S. Securities Act or an applicable exemption from the registration requirements thereunder.                               those anticipated, estimated or intended. Accordingly, readers should not place undue reliance on forward-looking
                                                                                                                                             statements or information. The Company undertakes no obligation to update or reissue forward-looking information as a
       All dollar amounts referenced herein, unless otherwise indicated, are expressed in Canadian dollars.                                  result of new information or events except as required by applicable securities laws.

    Cautionary Note Regarding Forward-looking Information                                                                                 Technical Information

       The information contained herein contains “forward-looking statements” within the meaning of the United States Private                All of the scientific and technical information in this presentation has been reviewed and approved by Mr. Steve Blower,
       Securities Litigation Reform Act of 1995 and “forward-looking information” within the meaning of applicable Canadian                  P.Geo., Vice President – Exploration & Development for IsoEnergy. Mr. Blower has verified the sampling, analytical, and
       securities legislation. “Forward-looking information” includes, but is not limited to, statements with respect to the                 test data underlying the information or opinions contained herein by reviewing original data certificates and monitoring
       activities, events or developments that the Company expects or anticipates will or may occur in the future, including,                all of the data collection protocols. Mr. Blower is a qualified person for the purposes of National Instrument 43-101 –
       without limitation, planned exploration activities and completion of the acquisition of the Property. Generally, but not              Standards of Disclosure for Mineral Projects (“NI 43-101”).
       always, forward-looking information and statements can be identified by the use of words such as “plans”, “expects”, “is
       expected”, “budget”, “scheduled”, “estimates”, “forecasts”, “intends”, “anticipates”, or “believes” or the negative                   For additional information regarding the Company’s Radio project please refer to the Technical Report entitled “Technical
       connotation thereof or variations of such words and phrases or state that certain actions, events or results “may”, “could”,          Report for the Radio Project, Northern Saskatchewan” dated effective August 19, 2016 prepared by Tim Maunula,
       “would”, “might” or “will be taken”, “occur” or “be achieved” or the negative connotation thereof.                                    available under IsoEnergy’s profile on www.sedar.com. Mr. Maunula is a “qualified person” under NI 43-101.

       Such forward-looking information and statements are based on numerous assumptions, including among others, that the                   For additional information regarding the Company’s Thorburn Lake project please refer to the Technical Report entitled
       results of planned exploration activities are as anticipated, the price of uranium, the anticipated cost of planned                   “Technical Report for the Thorburn Lake Project, Northern Saskatchewan” dated effective September 26, 2016 prepared
       exploration activities, that general business and economic conditions will not change in a material adverse manner, that              by Tim Maunula, available under IsoEnergy’s profile on www.sedar.com. Mr. Maunula is a “qualified person” under NI 43-
       financing will be available if and when needed and on reasonable terms, and that third party contractors, equipment and               101.
       supplies and governmental and other approvals required to conduct the Company’s planned exploration activities will be
       available on reasonable terms and in a timely manner. Although the assumptions made by the Company in providing                       For additional information regarding the Company’s Larocque East project please refer to the Technical Report entitled
       forward-looking information or making forward-looking statements are considered reasonable by management at the                       “Technical Report for the Larocque East Project, Northern Saskatchewan” dated effective May 15, 2019 prepared by Tim
       time, there can be no assurance that such assumptions will prove to be accurate.                                                      Maunula, available under IsoEnergy’s profile on www.sedar.com. Mr. Maunula is a “qualified person” under NI 43-101.

2   IsoEnergy.ca                                                                                                                                                                                                                             TSXV: ISO OTCQX: ISENF
Proudly Exploring for Uranium in Saskatchewan's North - TSXV: ISO OTC: ISENF
Background & Approach

                Company formed in 2016 – 5 Eastern Athabasca properties spun out of NexGen Energy
                Clear strategy at a difficult time in the uranium market – presented an opportunity for the company
                Built a portfolio of 24 High Quality Properties

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Proudly Exploring for Uranium in Saskatchewan's North - TSXV: ISO OTC: ISENF
Eastern Athabasca Portfolio

                                  Original Strategy
                                     Stake/acquire as much prospective ground in the eastern Athabasca as possible
                                     Drill around mineralized intercepts not adequately followed up post 2011

                                  24 High Quality Properties, including:
                                     Larocque East is home to the Hurricane Zone high-grade uranium discovery
                                     Geiger covers numerous intersections of weak uranium and uranium pathfinder
                                      mineralization, many walk-up drill targets, and thin sandstone cover
                                     Collins Bay Extension acquisition located along-trend of, and within 7km of, the
                                      Rabbit Lake uranium mine and mill complex
                                     Thorburn Lake 7km east of the Cigar Lake Mine. Several drill holes have hit
                                      uranium mineralization. Numerous target areas remain
                                     Radio located 2km east along strike of the Roughrider deposit, which Rio Tinto
                                      acquired for $587M in February 2012

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Proudly Exploring for Uranium in Saskatchewan's North - TSXV: ISO OTC: ISENF
Hurricane Discovery
5   IsoEnergy.ca                         TSXV: ISO OTCQX: ISENF
Proudly Exploring for Uranium in Saskatchewan's North - TSXV: ISO OTC: ISENF
Flagship Asset – Larocque East Hurricane Zone
                                                 100% owned by ISO
                                                 May 2018: Acquired for $20K and 1M shares
                                                 July 2018: Hurricane discovered
                                                             8.5m @ 1.26% U3O8; 2.5m @ 3.58% U3O8
                                                 2020: 44 holes, 17,400m in Q1 & Q4
                                                 2021: 30 holes drilled summer 2021
                                                 2022: 12,000m program being completed
                                                 Drilling Highlights:
                                                       LE20-32A: 8.5m @ 19.6% U3O8
                                                       LE20-34: 8.5m @ 33.9% U3O8
                                                       LE20-51: 7.5m @ 14.5% U3O8
                                                       LE20-52: 7.5m @ 22.7% U3O8
                                                       LE20-53: 10.5m @ 11.7% U3O8
                                                       LE20-54: 9.0m @ 12.8% U3O8
                                                       LE20-57: 10.0m @ 11.7% U3O8
                                                       LE20-64: 5.0m @ 48.8% U3O8
                                                       LE20-76: 7.5m @ 38.8% U3O8 (incl. 3.5m @ 74.0%)
                                                       LE21-78C1: 12.0m @ 5.2% U3O8
                                                       LE21-87A: 7.5m @ 4.5% U3O8
                                                       LE21-107: 6.5m @ 20.4% U3O8
                                                 Hurricane zone is shallow, only 325m below surface
                                                 Numerous other prospective targets on property

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Proudly Exploring for Uranium in Saskatchewan's North - TSXV: ISO OTC: ISENF
Hurricane Zone Drilling
                                                     Drilling Highlights:

                              Some of the thickest
                               and highest-grade
                               intercepts drilled
                                since NexGen’s
                                discovery of the
                                 Arrow Deposit

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Proudly Exploring for Uranium in Saskatchewan's North - TSXV: ISO OTC: ISENF
Athabasca Basin Deposit Depths

         Hurricane located at relatively shallow depth compared to many other Basin deposits – at 325m below surface

88   IsoEnergy.ca                                                                                              TSXV: ISO OTCQX: ISENF
Proudly Exploring for Uranium in Saskatchewan's North - TSXV: ISO OTC: ISENF
Exploration

     Summer 2021
     •    Over 16,000m of drilling on Larocque East and Geiger
     •    Geophysics completed on Larocque East, and Collins
          Bay Extension

     Winter 2022
     •    11,900m of drilling planned on Larocque East
            •      2,400m –follow up on mineralization
                   intersected at Hurricane last summer
            •      9,500m – exploration of conductive trend
     •    Ground geophysical surveys at Geiger, Ranger and
          Hawk projects

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Proudly Exploring for Uranium in Saskatchewan's North - TSXV: ISO OTC: ISENF
Larocque East – 2021Drilling & Follow Up

                                                Hurricane
                                                 16 drill holes completed to define limits
                                                  of Hurricane Zone
                                                     Expanded footprint to south
                                                     Second high-grade lens discovered
                                                     Evaluated western J-L fault
                                                        corridor
                                                 Best result – 6.5m @ 20.4% U3O8 in
                                                  LE21-107
                                                 LE21-101 intersected weak
                                                  mineralization in weak J-L corridor
                                                     Winter 2022 follow-up target
                                                 2,400m to follow-up LE21-101 and test
                                                  conductor south of Hurricane

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Larocque East – Hurricane Zone

                                        Key Features of a Significant Discovery
                                         High grade mineralization over widths and
                                          thicknesses seen at major deposits – up to
                                          12m thick x 125m wide
                                         Known uranium mineralization extends over
                                          1km of strike length
                                         Mineralization occurs on a major basement
                                          tapping fault system that caused a ridge in
                                          the sub-Athabasca unconformity
                                         Relatively shallow depth of 325m
                                         40km from Orano’s McClean Lake mill
                                         No lake or water cover
                                         Borders Cameco/Orano Dawn Lake property
                                              Dawn Lake JV active adjacent to
                                               Hurricane
                                         New low-cost mining techniques emerging
                                          for unconformity hosted uranium deposits

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Larocque East – 2021Drilling

                                    Exploration
                                     Fourteen drill holes primarily testing
                                      coincident EM and Resistivity targets
                                     LE21-94, -98 intersected significant,
                                      altered basement structure and UC
                                      expression
                                     LE21-92, -96 intersected basement
                                      alteration zone

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Exploration – Winter 2022

         Ground Geophysics       January: Geiger Geophysics
         Drilling
                                  Ground EM in two underexplored areas

                                 January-March: Larocque East Drilling
                                  Follow-up 2021 drilling results and 2019-2021
                                   geophysical targets

                                 March-April: Ranger & Hawk Geophysics
                                  Ground EM to follow-up historical airborne
                                   conductors

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Larocque East – 2022 Winter Drilling

                                            Excellent Exploration Potential
                                            East of Hurricane
                                             15km of conductors related to the
                                              Larocque Trend are present at
                                              Larocque East
                                             Pre-2022 IsoEnergy drilling limited to
                                              2019 Resistivity footprint
                                             Several historical drill holes east of
                                              the Hurricane zone have intersected
                                              weak uranium mineralization and/or
                                              elevated geochemistry
                         2019 2021           9,500m to follow up existing drilling
                         Resistivity          and test geophysical targets
                                             Prioritize targets inaccessible in
                                              summer

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Geiger – Summer 2021 Drilling

                                      Last drilled summer 2018 immediately before Hurricane discovery
                                      12 holes completed in July/August 2021 – 4,428m
                                      A total of ~135 kilometres of graphitic conductors
                                      Several mineralized intersections are present including high grade
                                       basement mineralization up to 2.74% U3O8 over 1.2 m in drill hole HL-50
                                      Newly discovered alteration zone intersected

                                                                                          Section Q3-3700E
                                                                                          (Drill Holes GG21-21
                                                                                          and GG21-27)

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Geiger – Winter 2022 Ground Geophysics

                                    Shallow and Underexplored
                                     Drill Target Generation
                                     Ground Electromagnetic surveys underway in prospective Q23 and Q48 areas
                                     Both areas contain historical conductors within magnetic low zones and
                                      shallow depth to unconformity (250-275m)
                                     Q23
                                       Only two drill holes in area including one abandoned before target
                                       Both intersected favourable sandstone alteration and structure
                                       One intersected weak mineralization in the basement
                                     Q48
                                       Lies along strike of Murphy Lake occurrence (0.25% U3O8 / 6.0m) and
                                        strong alteration with anomalous geochemistry in H5 area
                                       Single drill hole completed in area intersected major zone of faulting and
                                        alteration in sandstone

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Collins Bay Ext. – Summer 2021 Airborne Geophysics

           Airborne Geophysics
            567 line-kilometer geophysical survey
             completed over southwestern portion
             of the project
            Intended to map the Tent-Seal and
             Collins Bay trends and survey
             radioactive anomalies
            Finalized dataset received February
             2022; interpretation underway
            On trend of former mines – Eagle
             Point and Collins Bay A Zone

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Hawk and Ranger – Winter 2022 Ground Geophysics
      Ground EM surveys planned at Hawk and Ranger to advance projects to drill ready state

                                                   Hawk
                                                      Covers at least 10 km of prospective magnetic low corridor hosting EM conductors
                                                      Single drill hole within project failed to intersect conductive rocks – entire trend is untested
                                                      Six widely-spaced survey lines planned to generate targets for first-pass diamond drilling
                                                      Anticipated March-April 2022

                                                              Ranger
                                                                 Ten survey lines to pinpoint historical conductors
                                                                 Limited historical drilling is confined to southeastern corner of survey area
                                                                 Shallow depth to Unconformity (230-300m)
                                                                 Anticipated March 2022

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Market & Corporate Overview
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Strong Market Fundamentals
     Market continues to strengthen – all signs pointing in the right direction                                              UxC U3O8 Prices
      Market – Supply/Demand Fundamentals
         440 operating reactors in 32 countries; 50 reactors under construction in 18 countries
         Uncovered uranium requirements – 2.27 billion lbs between 2022 and 2040
             40% uncovered by 2027; 68% in 2032

      Changing Market and Significant Geopolitical Shift Underway
         Continuing Impact of SPUT; Kazakh Fund; Unconventional spot purchasing by non-traditional entities;
         Kazakhstan – Civil unrest; Russia – invasion of Ukraine will have far-reaching impact on market in near
          term and for years to come – Suspension Agreement/Sanctions/Ethics

      Production – Secondary Supplies                                                                       Uncovered Utility Requirements
         Measured approach to McArthur River restarting, following almost 4 year curtailment
         End of life for longstanding supply sources – Rio Tinto Ranger; Orano’s Cominak
         Accelerated inventory and secondary supply drawdown
                   Expect 66 million lbs needed in 2022 – accounting for 33% of total supply

      High Level – Improving Narrative Globally
         Growing acceptance of nuclear in the fight against climate change – positive ESG investment
         Strengthening commitments to nuclear
           Numerous countries/sovereigns – increased interest in building/growing programs
           China’s 14th 5 Year Plan – 70 GWe nuclear target by 2025 (48 GWe end of 2020)
           France’s recommitment to its nuclear program; UK nuclear growth; new jurisdictions
                                                                                                                                                   Source: UxC
20   IsoEnergy.ca                                                                                                                            TSXV: ISO OTCQX: ISENF
Capital Structure

                    1 Year Stock Chart | TSXV: ISO                                Share Structure
                                                     Issued & Outstanding Shares                                        106,501,270
                                                     Stock Options                                                          8,166,667
                                                     Warrants                                                                                 0
                                                     Convertible Debt (US$6 million)(1)                                     8,520,000
                                                     Fully Diluted Shares                                               123,187,937
                                                     Cash                                                            ~C$8.4 Million
                                                     (1) Convertible at C$0.88 per share with the exact number of shares to be issued based
                                                         on the CAD:USD exchange rate at the time of conversion.

                                                                                                             Analyst Coverage
                                                                                                             Haywood Securities Inc.
                                                                                                             Colin Healey

                                                                                                             PI Financial
                                                                                                             Chris Thompson

21   IsoEnergy.ca                                                            1.    Share Structure as at Feb. 1, 2020 TSXV: ISO OTCQX: ISENF
Management

22   IsoEnergy.ca   TSXV: ISO OTCQX: ISENF
Board of Directors

                        Leigh Curyer                 Tim Gabruch                     Trevor Thiele               Richard Patricio               Chris McFadden
                           Chairman                  Director & CEO                      Director                      Director                      Director
                        Chartered Accountant       25+ years experience in        Chartered accountant         Lawyer with 20+ years        Chairman of NexGen
                         with 20+ years              the uranium mining and          with 30+ years                capital market                Energy Ltd.
                         experience and former       nuclear energy industries       experience in capital         experience
                                                                                                                                                Lawyer with 20+ years
                         CFO of Southern Cross                                       markets including CFO
                                                    20+ years with Cameco                                        President and CEO of          experience in
                         Resources (now                                              of major Australian
                                                     Corp, including VP of                                         Mega Uranium Ltd.             exploration and mining
                         Uranium One)                                                Agribusiness (Elders
                                                     Marketing
                                                                                     and Viterra)                 Former CEO of Pinetree       Former Commercial
                        President and CEO of
                                                    Former VP Commercial                                          Capital                       General Manager and
                         NexGen Energy Ltd.
                                                     Denison and Chief                                                                           Head of Legal for Tigers
                                                     Commercial Officer at                                                                       Realm Group and Tigers
                                                     Uranium Participation                                                                       Realm Coal
                                                     Corp
                                                                                                                                                Former Commercial
                                                                                                                                                 General Manager for Rio
                                                                                                                                                 Tinto

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Investor Highlights

                           IsoEnergy Highlights
                                                      Strategic steps taken in down market – world class
                                                      portfolio created. Only junior with a new high-
                                         Discovery   grade uranium discovery at a time when uranium
                                                      market fundamentals and nuclear industry
                                                      narrative continues to strengthen

                                                      Outstanding team of geologic, financial and
                                          Team       governance professionals. With unwavering
                                                      continued support from NexGen

                                                      Geopolitical setting of projects is a strategic
                                                      advantage. Saskatchewan and Canada are highly
                                         Location    ranked mining jurisdictions
                                                      Further supported by nearby transport and energy
                                                      infrastructure and an existing mill

                                                      Tightly held.           maintains ~51% - provides
                                         Structure   IsoEnergy with tremendous support and strategic
                                                      advantage. Significant holding by various
                                                      institutions and other strategic investors
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Contact

            Management
           Tim Gabruch
           President & Chief Executive Officer
           Email: tgabruch@isoenergy.ca
           Direct: +1.306.261.6284

            Investor Relations
            Kin Communications
            Email: iso@kincommunications.com
            Direct: +1.604.684.6730

25   IsoEnergy.ca                                TSXV: ISO OTCQX: ISENF
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