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Oral Health Newsbites ISSUE 1 | MAY 2022 P3 P4 P6 New automatic The link between Education Day 2021 RPD design system periodontitis and andORH ACP for partially risk of gestational Excellence in edentulous patients diabetes Teaching Awards Oral Health Newsbites | Issue 1 May 2022 1
Oral Health Newsbites is a bi-annual newsletter which highlights our key innovations and events under clinical research and education. In this first issue, we share some of the meaningful work and achievements of our clinicians, researchers, and educators who have contributed to the future of patient care and innovation. The SingHealth Duke-NUS Oral Health Academic Clinical Programme (ORH ACP) was launched in August 2014. The ORH ACP brings together three clinical departments and six specialties across National Dental Centre Singapore (NDCS), KK Women’s & Children’s Hospital (KKH), SingHealth Polyclinics (SHP) and Changi General Hospital (CGH). ACP’s main priorities include focusing on the four key Research Themes (Bone Bioengineering, Oral Devices and Therapeutics, Genomics / Biomarker Discovery and Health Services Research), nurturing budding clinician scientists, as well as collaborating with Duke-NUS on joint certification of Senior Residency and Fellowship Programs. CLINICAL INNOVATION 3 New automatic RPD design system for partially edentulous patients PanoShield: Face shields that offer panoramic protection RESEARCH 4 The link between periodontitis and risk of gestational diabetes Contents 5 A counterfactual approach onthe effect of metabolic syndrome on tooth loss: a population-based study EDUCATION 6 Education Day 2021 and ORH ACP Excellence in Teaching Awards OVERVIEW 7 FY21 Grant and Award Recipients 2 Issue 1 May 2022 | Oral Health Newsbites
CLINICAL INNOVATION New automatic RPD design system for partially edentulous patients A more pleasant patient journey for denture wearers N DCS, together with service and meet the design patterns to fit the A*STAR and ST rising demands of denture geometry of the patient. Engineering, developed a production for Singapore’s software prototype to generate ageing population. The team proposed using a printable, patient-specific selective laser melting (SLM) Removeable Partial Dentures The three-step system technique to mass produce (RPD) framework file from encompasses of the the Chrome-cobalt denture intra-oral scans, automatically. automated tooth identification, frame precisely. It could The new automatic RPD design digitisation of RPD design potentially improve the system aims to reduce the and RPD voxelisation, the efficiency of denture production, time spent on denture SmartRPD software will enhance the quality of treatment production, improve the automatically process teeth and patient experience, and throughout of the denture configurations and generate reduce cost. NDCS/NDRIS Stakeholders Dr Yu Na Dr Seetoh Yoong Liang Clinician Scientist & Head & Senior Consultant Principal Investigator Prosthodontic Unit Senior Dental Surgeon Department of Restorative Prosthodontics Unit Dentistry, NDCS Department of Restorative Dentistry, NDCS Partners: Temasek Holdings (Funder) A*STAR (Partner) ST Engineering (Partner) PanoShield: Face shields that offer panoramic protection Enhancing safety for healthcare workers C linicians who perform The PanoShield is developed with the aims of enhancing aerosol-generating peripheral protection, being compatible with essential procedures are supporting devices required by various clinical sub-specialties, recommended to don Personal and improving the user’s comfort level. Protective Equipment (PPE) including gloves, protective It can be worn over existing PPE, is universally fitting, comfortable outerwear, a face shield, and and secure for long hours, has anti-fogging properties and is N95 masks, to prevent direct easily scalable for manufacturing. deposition of respiratory droplets on their faces. Adjustable size However, it was found that Flexible coverage there are protection gaps despite such PPE measures – ineffective protection against fine respiratory droplets/ aerosols, inadequate periphery Anti-fog coating protection, obtrusive operational constraint, and doffing risks. NDCS/NDRIS Stakeholders Dr Yu Na Clinician Scientist & Dr Constance Teo Ee Hoon Principal Investigator Senior Consultant, Department of Senior Dental Surgeon Otorhinolaryngology – Head and Neck Prosthodontics Unit Surgery, SGH Head, SingHealth Department of Restorative Dentistry, Duke-NUS Head and Neck Centre NDCS Partners: SingHealth Medical Technology Office (SingHealth MTO) Oral Health Newsbites | Issue 1 May 2022 3
RESEARCH The link between periodontitis and risk of gestational diabetes Congratulations to Dr Preethi Prajod, who was awarded the NMRC Clinician Scientist Individual Research Grant - New Investigator Grant (CNIG) in 2020. F or the past few years, Dr Preethi has been treating periodontal working on the functional attributes of disease before and during microbiota and immune responses at the pregnancy may reduce intersection of oral-systemic health. Backed maternal and perinatal with this funding, her research study would morbidity associated with GDM and examine the prospective association between prevent type 2 diabetes after pregnancy. periodontitis and the risk of Gestational Most women do not seek oral health care during Diabetes Mellitus (GDM) in pregnant women. pregnancy despite evidence that poor oral One in every five pregnant women in Singapore health can adversely impact the health of a have been observed to develop GDM. Women pregnant woman and her child. Concern about with GDM are at increased risk for foetal and the safety of dental services during pregnancy maternal complications and are also associated restrict their visit to clinics. The strategy to with about seven-fold increased risk for change the perception of pregnant women is developing type 2 diabetes mellitus in later life. to include dental health education as an integral part of prenatal health care. To potentiate Periodontitis is treatable. If periodontal disease general health and well-being, women should is confirmed as a risk factor for GDM through routinely be counselled about the safety this initiative, it will open doors to intervention and maintenance of good oral health habits studies to prevent GDM. Improving oral health and throughout their pregnancy. NDCS/NDRIS Stakeholders A/Prof Chaminda Dr Preethi Prajod Jayampath Research Fellow, Seneviratne ORH ACP NDRIS Adjunct Professor NDCS Partners: KK Women’s and Children’s Hospital (KKH) Academic Center for Dentistry Amsterdam (ACTA) 4 Issue 1 May 2022 | Oral Health Newsbites
RESEARCH A counterfactual approach on t he effect of metabolic s yndrome on tooth loss: a population-based study The link between oral This analysis was based on and general health is by data from a cohort study (2009–2014) with adults aged default bidirectional, which 20+ from Southern Brazil. MetS makes the establishment (exposure), lack of functional of causality a core issue in dentition and number of health research. Prof Marco lost teeth (outcomes) were assessed using self-reported, Peres’ and his team’s findings, lab and clinical data. Possible based on cutting-edge confounders included sex, age, weights (a counterfactual epidemiological tools, provide family income, educational analytical method) was also level, smoking status and sugar used to enhance group evidence on the effect of comparability and estimate consumption. The effect of MetS Metabolic Syndrome (MetS) on the outcomes was estimated causal effects. Data imputation on tooth loss. using conventional logistic or was used to deal with missing negative binomial regression values. E-value was used to MetS and tooth loss are prevalent assess the effect of unmeasured models. Marginal structural conditions that negatively confouders. modeling (MSM) with stabilized affect health and quality of life, increases the cost of health care systems, and exacerbates 1,283 participants had available information for the outcomes. social problems and inequalities. Individuals with MetS were more likely to experience a lack of Even though some studies have functional dentition than those without MetS [odds ratio (OR) addressed the association from logistic regression 1.7, 95% CI 1.0-2.9; OR from MSM 3.2, 95% between MetS and tooth loss, the CI 2.3-4.6]. Moreover, the number of teeth lost was 20% higher investigation of this relationship in participants with MetS compared to those without MetS in using an appropriate statistical conventional analysis (mean ratio [MR] 1.2, 95% CI 1.1- 1.3). The approach and a representative MR increased to 1.7 (95% CI 1.5-2.0) when using MSM. sample of the population remains unexplored in the literature. This study aimed to investigate Direct acyclic graphic for the • Smoking the effect of MetS on tooth loss effect of MetS on theoccurrence Status • Sugar in a population-based sample. It of tooth loss. Consumption • Sex was hypothesised that MetS has • Age an effect on tooth loss. Studying Exposure: Metabolic Syndrome • Income • Educational Level • Tooth Loss this topic is essential to inform the Confounding factors: Sex, best strategies to prevent tooth Age, Income, Educational loss in populations with MetS and Level, Smoking Status, Sugar • Metabolic to encourage public policies that Consumption Syndrome approach common risk factors to Outcome: Tooth Loss oral and general health. NDCS/NDRIS Stakeholders Marco A. Peres Karen G. Peres Supervisor, Co-supervisor, NDRIS/NDCS, NDRIS/NDCS, Duke-NUS Duke-NUS Partners: This study is part of Marina Leite Souza Gustavo G. Nascimento David A. Gonzalez Chica the PhD thesis of (PhD student, UFSC, Brazil); (collaborator, Aarhus University, Denmark); (collaborator, University of Adelaide, Australia) Oral Health Newsbites | Issue 1 May 2022 5
EDUCATION Education Day The ORH ACP Excellence in Teaching Awards were conferred to: 2021 andORH ACP Excellence AUXILIARY in Teaching PROGRAMME Awards Dr Quek Heng Chuan Senior Consultant, Prosthodontic Unit, Department of Since 2015, Education Day Restorative Dentistry is an annual event held to commemorate our educators and learners. NDCS’s Education Day was held on 8 September last year, and comprised of a lunchtime talk by Dr Song Yi POST-GRADUATE Lin, Consultant, Department of Orthodontics, as well as Dr Bien Lai the ORH ACP Excellence in Head and Senior Teaching Awards. Consultant, Paediatric Dentistry Dr Song’s talk – The Science Unit,Department of of Learning – delved into Restorative Dentistry methods to optimise the learning process, make it easier to learn, remember, and apply knowledge. The event was followed by a virtual Faculty Development Workshop, titled “Introduction to Team Based Learning Pedagogy”. It was facilitated by Dr Foo Lean Heong, Consultant, Periodontic Unit, Department of Restorative Dentistry, and Dr Chan Pei Yuan, Consultant, Endodontic Unit, Department of Restorative Dentistry. 6 Issue 1 May 2022 | Oral Health Newsbites
FY21 Grant and Award Recipients FY2021 Grants and Recipients Grant Recipient GLOBICS: The Global consortium of Oral health-related A/Prof Karen Peres Birth Cohort Studies Temasek Foundation Public Health Innovations Grant Dr Yu Na A*STAR Industry Alignment Fund - Industry Collaboration Cl A/Prof Goh Bee Tin Projects (IAF-ICP) Clinicial Scientist Award Dr Yu Na FY2021 Awards and Recipients Award Recipient Duke-NUS Hall of Master Academic Clinicians 2022 Cl A/Prof Goh Bee Tin SingHealth Publish! Award 2021 A/Prof Jaya Seneviratne Singapore Health Quality Service Award Cl A/Prof Chew Ming Tak Scan this QR code for more information about NDCS research publications. ndcs.sg ndcs-sg ndcs-sg www.ndcs.com.sg 7 Issue 1 May 2022 | Oral Health Newsbites
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