Highlights Semester One 2019 - University of Western Australia

 
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Highlights Semester One 2019 - University of Western Australia
Highlights
Semester One 2019
Highlights Semester One 2019 - University of Western Australia
Global impact
                                        UWA’s Faculty of Health and
                                        Medical Sciences is developing
                                        future leaders to meet the global
                                        health challenges of tomorrow and
                                        seize opportunities in a rapidly
                                        changing world.
                                        Our mission is to advance life-long
                                        health through education, research
                                        and innovation.
                                        We offer world class training and          Through research-led teaching, we
                                        research opportunities in a wide           encourage the lifelong adaptation
                                        range of scientific and clinical           and assessment of new theories,
                                        disciplines to significantly benefit the   treatments and diagnostic techniques
                                        health of Australian and international     that incorporate a holistic approach
                                        communities.                               to health sciences and a more
                                                                                   sensitive interaction with patients.

                        We strive to deliver research-led teaching
                        in high-quality facilities and are
                        supported in this venture by leading
                        academics, valued alumni and expert
                        health professionals.

2 The University of Western Australia
Highlights Semester One 2019 - University of Western Australia
UWA has acquired an international reputation for research
excellence in health and medicine, attracting world class
researchers across a wide range of disciplines and diverse fields.
Our exceptional community of researchers work across               The achievements of our researchers have been globally
health and medical research institutes, hospitals and              recognised in recent ranking announcements, including
other health care providers. At the core of their work is          the Academic Ranking of World Universities (ARWU). UWA
translating discoveries into patient care, community               also improved 5 places, from 91 to 86, in the 2020 QS World
health and health policy.                                          University Rankings.

 Clinical Medicine
 at UWA is ranked

           8             thin the
                            world                            and     1         st
                                                                                     Australia
                                                                                                 in

                                                                                                               (ARWU 2019)

                                   Awarded

                                  $19.3M                                                        356
                                                                                                 PhD Students (2019)
                                   in NHMRC funding (2018)                                       in Health and Medical Sciences

 Ranked
 in top       35
 in the world for Biological
                                                               1059
                                                               Research Publications
 Sciences and Human Biological                                 (Jan-June 2019) in Health
 Sciences (ARWU, 2019)                                         and Medical Sciences

                                                                                                           uwa.edu.au/health 3
Highlights Semester One 2019 - University of Western Australia
Federal Funding boost
for indigenous mental
health services

                                          The program will test models in ‘real
                                          world’ mental health service settings
                                          which will then be developed for primary
                                          mental health and specialist services,
                                          both for Indigenous and mainstream users.”

A multidisciplinary research program      Lead researcher Professor Pat                Professor Sean Hood, Head of the UWA
has received $5 million to improve        Dudgeon, from the UWA Poche Centre           Division of Psychiatry and the Faculty’s
the delivery of mental health services    and School of Indigenous Studies, said       Associate Dean (Community and
for Australia’s Indigenous population.    the project would play a vital role in       Engagement), said this is an important
                                          improving Indigenous wellbeing and           program because it leverages the
The funding is part of the Federal        suicide prevention across Australia.         unique breadth of experience at UWA.
Government’s Medical Research Future
Fund (MRFF) Million Minds Mission and     “The program will involve researchers        “As an integrated cross-faculty research
follows calls for a new approach to        from many different parts of the             program we have been able to use
Indigenous mental health services to       University, providing a multidisciplinary    cutting-edge mathematical techniques
foster and promote cultural values and     approach to solving some of our              we developed in public and private
strengths, as well as empowering those     country’s ‘wicked’ problems,” Professor      hospital settings and applied these to
who use the services.                      Dudgeon said.                                Indigenous mental health in a culturally
                                                                                        sensitive manner,” Professor Hood said.
Researchers will work with Indigenous     “The models will feature integrated
service users to develop clinically and    mental health, alcohol and drug,            The multidisciplinary research team
culturally capable Indigenous mental       suicide prevention and social and           will be led by senior Indigenous
health service models and establish        emotional wellbeing services and            researchers and include partnerships
how they can best work within families     enhanced workforce capabilities to          with Indigenous-specific and other
and communities. They will also look at    meet complex needs,” she said.              mental health service providers.
how services can better prevent
mental health difficulties and suicide
and consider cultural healers’ work
with service users.

4 The University of Western Australia
Highlights Semester One 2019 - University of Western Australia
Pleural medicine leader named
cancer researcher of the year
A researcher from the Medical                Professor Lee led the use of a new             “This award is an important recognition
School has been named Cancer                 drainage device (called the indwelling          of the effort of my very dedicated team
Council Western Australia 2019               pleural catheter) that allows, for the          of research fellows and collaborators
Cancer Researcher of the Year.               first time, patients to drain their fluid at    who are devoted to improving patient
                                             home if and when they become                    care,” he said.
Professor Gary Lee was recognised for        breathless.
his research into pleural effusion, a                                                       Professor Lee follows UWA’s
build-up of fluid in the chest which         He set up the AMPLE (Australasian              internationally recognised asbestos-
affects more than 8,000 cancer               Malignant Pleural Effusion) network            related diseases expert Professor Anna
patients a year in Australia. Pleural        across hospitals in Australia, New             Nowak who was awarded Cancer
effusion especially effects those with       Zealand, Hong Kong, Singapore and              Researcher of the Year in 2018.
lung and breast cancers and most of          Malaysia. Through the AMPLE network,
those with mesothelioma, a fatal             he led two multicentre randomised              Professor Nowak was also awarded
cancer of the lining of the lung caused      trials that showed indwelling catheter         almost $100,000 by Cancer Council this
by exposure to asbestos.                     treatment improves patient symptoms            year to undertake laboratory testing to
                                             and quality of life.                           understand why some patients with
The resulting fluid accumulation as part                                                    mesothelioma responded better to a
of these diseases often causes               Most importantly it allows patients            combination of chemotherapy and
disabling breathlessness and requires        with advanced cancers to spend                 immunotherapy.
repeated invasive procedures to drain.       significantly less time in hospital and
Management of cancer-related                 more time at home with family. From a
effusions accounts for more than 8,000       healthcare perspective, this treatment
bed days and more than 10 million care       can save more than 14,000 hospital
costs in each year in public hospitals of    bed days across Australia a year.
Western Australia alone.

Professor Lee divides his time between
working as a professor of respiratory
medicine at UWA and a consultant
                                                        We are proud to show
chest physician and director of pleural
services at Sir Charles Gairdner Hospital.              that investigators from
                                                        WA could design and lead
Western Australia is the first state
where all tertiary hospitals have a
                                                        high-quality, multicentre
specialist pleural physician, all trained               clinical trials that impact
by Professor Lee at Sir Charles Gairdner                on clinical practice
Hospital. Professor Lee was
instrumental in setting up pleural                      worldwide.”
medicine as a new subspecialty in
Australia. This has significantly
improved the diagnosis and
management journey of cancer
patients with pleural effusions.

                                                                                                                 uwa.edu.au/health 5
Highlights Semester One 2019 - University of Western Australia
Babies make room in
the womb for bacteria
Our exposure to bacteria begins before we’re born, according to new research led by Dr Lisa Stinson
from the division of Obstetrics and Gynaecology. The study, published in Frontiers in Microbiology,
used rigorous contamination controls to confirm exposure to bacteria begins in the womb.

Researchers collected amniotic fluid          “Over the last decade, numerous studies have detected bacterial
samples from 50 healthy women
                                               DNA in amniotic fluid and first-pass meconium (baby’s first poo),
undergoing planned caesarean
deliveries and found nearly all contained
                                               challenging the long-held assumption the womb is sterile,” Dr
bacterial DNA. They subsequently found         Stinson said.
all 50 newborns had bacteria in their first
bowel movement.                               The researchers said it was important      “Interestingly, the meconium microbiome
                                              to conclusively determine whether a         varied hugely between individual
                                              healthy womb contained bacteria             newborns. The amniotic fluid
                                              because the ‘fetal microbiome’ was          microbiome for the most part
                                              likely to have a significant impact on      contained typical skin bacteria,
                                              the developing immune system, gut           such as Propionibacterium acnes
                                              and brain.                                  and Staphylococcus species.”

                                              To settle the issue, the research team     None of the women who
                                              took strict measures to eliminate
                                                                                         took part in the study nor
                                              bacterial contamination when analysing
                                              amniotic fluid and meconium samples.
                                                                                         their babies had any sign of
                                                                                         infection. In fact, the fetal
                                              For example, they purified the reagents    microbiome may prove to be
                                              used to detect bacterial DNA in the        a beneficial regulator of early
                                                samples, by adding an enzyme
                                                  which digests DNA remnants from
                                                                                         development.
                                                    bio-manufacturing.
                                                                                         “We found that levels of important
                                                                                          immune modulators in meconium and
                                                        “Despite these measures, we
                                                                                          inflammatory mediators in amniotic
                                                           still found bacterial DNA
                                                                                          fluid varied according to the amount
                                                               in almost all samples,”
                                                                                          and species of bacterial DNA present,”
                                                                  Dr Stinson said.
                                                                                          Dr Stinson said.

                                                                                         “This suggests the fetal microbiome has
                                                                                          the potential to influence the
                                                                                          developing fetal immune system.”

                                                                                         Dr Stinson’s research was carried out
                                                                                         under the supervision of Professor
                                                                                         Jeffrey Keelan, Head of the School of
                                                                                         Biomedical Sciences and Dr Matt
                                                                                         Payne, Research Fellow in the Division
                                                                                         of Obstetrics and Gynaecology at the
                                                                                         UWA Medical School.

6 The University of Western Australia
Highlights Semester One 2019 - University of Western Australia
“Once the GP has this information base,
                                                                                         they can then work through the
                                                                                         platform to develop a personal care
                                                                                         plan for the patient,” she said. “The
                                                                                         platform contains 112 clinical practice
                                                                                         guidelines as well as the LactaPedia
                                                                                         glossary and 21 information sheets
                                                                                         that can be printed out during the
                                                                                         consultation or emailed to patients.”

                                                                                         LactaPedia is an online lactation
                                                                                         dictionary for science and medicine
                                                                                         that sets the international standard for
                                                                                         breastfeeding language. It was created
                                                                                         by Ms Boss and Emeritus Professor
                                                                                         Peter Hartmann to address the lack of
                                                                                         consistency in lactation-related

 Lactamap to support                                                                     terminology and help counteract some
                                                                                         of the conflicting advice women

 GPs caring for
                                                                                         receive when breastfeeding.

                                                                                         It defines more than 560 terms

 breastfeeding mums                                                                      associated with lactation, including
                                                                                         physiology, the composition of human
                                                                                         milk and conditions that affect
                                                                                         lactation. The lactation glossary can
 Researchers from the School of Allied Health have launched a world-first online         be freely accessed by medical
 lactation care support system called LactaMap to support GPs who are helping            professionals and scientists as well as
 patients who have problems breastfeeding.                                               the general public.

 Lead researcher Melinda Boss               “Lactation completes the reproductive        As reported in the Journal of Human
 said LactaMap was developed                 cycle but is often considered outside of    Lactation, early weaning represents a
 specifically to provide doctors with        the scope of modern medicine.               major public health concern and
 an evidence-based program they can          Conflicting advice is one of the most       results in an estimated $4 billion loss
 use during consultations to help treat      common factors that impact a                to the Australian economy each year.
 mothers and babies experiencing             mother’s confidence in her ability to
 lactation issues.                           initiate and sustain breastfeeding.”        LactaMap is accessible to doctors free
                                                                                         of charge. The research team gratefully
“Unlike other medical guidelines,            Ms Boss said LactaMap addresses             acknowledges the support of major
 LactaMap is an online lactation care        breastfeeding difficulties by starting      sponsor the Family Larsson-Rosenquist
 support system for doctors to use at        with consideration of four key areas:       Foundation, as well as the support of
 the point of care, to support mothers       pain, milk transfer, maternal health        the Rotary Club of Southern District.
 and infants experiencing difficulty with    and infant health.
 breastfeeding,” Ms Boss said.

             Our hope is to create a common medical and scientific
             understanding that will help to normalise human lactation.”

                                                                                                             uwa.edu.au/health 7
Highlights Semester One 2019 - University of Western Australia
Faculty award winners

The Faculty congratulates all 2019 award winners. The following are
some highlights of staff and alumni achievements so far this year:
Senior Research Fellow Melinda Boss     Professor Wendy Erber and                 Professor Vera Morgan
WA Pharmacist of the Year Award,        Associate Professor Kathryn Fuller        Raine Medical Research Foundation
Western Australian Pharmacist Awards    Rio-Tinto Australia-Japan Collaborative   Collaboration Awards, 2018
                                        Program, Foundation for Australia-        Australasian Epidemiological
Dr Mitali Sarkar-Tyson                  Japan studies (FAJS)                      Association (AEA) Annual Meeting
Project Leader Award, Defence                                                     Awards, 2018
Materials Technology Centre (DMTC)      Professor John Newnham
                                        Finalist Western Australian of the Year   Dr Yael Perry
Dr Sally Brinkman                       Award, Australian Medical Association     Raine Medical Research Foundation
NHMRC Research Excellence Award,        (WA) Hippocrates Award                    Collaboration awards, 2018
2018 Career Development Fellowship
Scheme, National Health and Medical     Ms Glenda Kickett                         Dr Lee Nedkoff
Research Council                        Finalist Western Australian               Raine Medical Research Foundation
                                        of the Year Award                         Collaboration awards, 2018
Dr Dayse Tavora-Vieira
Researcher of the Year- SMHS-           Dr Angus Turner                           Dr Anabel Sorolla Bardaji
Excellence Awards                       Professionals Award, 2019 Western         Raine Medical Research Foundation
                                        Australian of the Year Awards             Collaboration awards, 2018
Professor Helen Milroy
First Indigenous AFL commissioner,      Professor Wendy Erber                     Associate Professor Lisa Wood
Australian Football League              Scientist of the Year Finalist            Pro Bono Australia Impact 25 Award,
                                        WA Premier’s Science Awards               Sax Institute Research Action Award,
Dr Jilen Patel                                                                    2018, 2018 Public Health Association
WA Young Achiever of the Year           Professor Ryan Lister                     of Australia WA Branch Policy and
Masonic Care WA/Freemasons              Scientist of the Year Finalist            Research Translation Award for 2018,
WA Community Service and                WA Premier’s Science Awards               Faculty Travel Award 2019
Volunteering Award
                                        Ms Hayley Passmore                        Ms Shannen Vallesi, Mr Craig
Dr Chan Cheah                           ExxonMobil Student Scientist              Cumming, Ms Angela Gazey, Mr
Woodside STEM Excellence Award,         of the Year Finalist                      Nick Wood and Nuala Chapple.
2019 Business News 40under40                                                      2018 Public Health Association of
                                        Ms Sharynne Hamilton
Associate Professor                     ExxonMobil Student Scientist              Australia WA Branch Policy and
Lynette Fernandes                       of the Year Finalist                      Research Translation Award for 2018
Senior Fellowship to Advance Higher                                               Dr Demelza Ireland
Education Academy, Advance Higher       Ms Kirsty McLean
                                        ExxonMobil Student Scientist              Faculty Excellence in Teaching
Education Academy                                                                 Award - Individual or Teams
                                        of the Year Finalist
Assistant Professor                                                               Associate Professor
Anna Waterreus                                                                    Christopher Peacock
Travel Award, Schizophrenia                                                       Faculty Excellence in Teaching
International Research Society,                                                   Award - Individual or Teams
Daniel Beck Memorial Award for
Schizophrenia Research

Please email comms-hms@uwa.edu.au with news of awards and achievements.

8 The University of Western Australia
Highlights Semester One 2019 - University of Western Australia
Our Schools

                                    Medical School                              School of Biomedical Sciences
Ms Amber Boyatzis                   UWA’s Medical School brings together        The School encompasses teaching and
Faculty Excellence in Teaching      the brightest students, experienced         research in a range of biological, medical
Award - Early Career                clinicians and committed researchers        and health-related fields. Offering both
                                    to unlock the greatest health challenges    undergraduate and postgraduate
Ms Natalia Popowicz                 of our day. We have a renowned              courses, students have the opportunity
Faculty Excellence in Teaching      research program carried out in             to learn about the intersection between
Award - Early Career                laboratories, hospitals and in the          human pathology and health, and an
                                    community at a patient level, and           awareness of the approaches and
Associate Professor Allison Imrie
                                    we offer a range of scientific and          applications of the biomedical scientific
Citation for Outstanding
                                    clinical research opportunities across      disciplines.
Contribution to Student Learning
                                    10 divisions.
Dr Susannah Warwick
Citation for Outstanding
Contribution to Student Learning

The Noisy Guts Project
National iAwards Finalist &
WAITTA INCITE Awards Winner,
Most Innovative Enabler in Health                                               School of Population
                                    School of Allied Health
Care, National iAwards Finalist                                                 and Global Health
                                    Allied health professionals work in
& WAITTA INCITE Awards Research
                                    the health, social and psychosocial         The School is a leading research,
& Innovation Project of the Year
                                    services care team, using specialised       teaching and service organisation
                                    skills to provide evidence-based            whose work influences health policies
QUEEN’S BIRTHDAY HONOURS:
                                    services to patients and other service      and practices. The School comprises
Professor Richard Pestell, AO
                                    users. The School offers professional       Population and Public Health, the
MBBS ‘82, DM ‘08
                                    entry to practice courses in pharmacy,      Western Australian Centre for Rural
Professor David Mackey, AO          podiatric medicine and social work,         Health (WACRH) and the Raine Study.
                                    as well as health professions               We take an evidence-based approach
Dr Bill Carroll, AM
                                    education courses for those wishing         through research, advocacy and
MBBS ‘73, MD ‘85
                                    to become educators in health.              health promotion to protect and
Associate Professor                                                             improve the health of communities.
Prudence Manners, AM
MD ‘01

Professor Dao-Yi Yu, AM
PhD ‘91                                                 Dental School
                                                        The UWA Dental School is WA’s only tertiary dental training
                                                        centre, offering aspiring and existing dentists a range of
                                                        practical and innovative postgraduate courses in a high-tech
                                                        dental and learning facility. Using state of the art dental
                                                        technology, our research contributes to the understanding
                                                        of oral diseases, their prevention and treatment.

                                                                                                    uwa.edu.au/health 9
Highlights Semester One 2019 - University of Western Australia
Doctor of Dental Medicine Career Mentor Café
Over 30 students and seventeen
alumni attended the UWA Dental
School annual Career Mentor Café on
Wednesday June 19 at Coffee
Anatomy, Harry Perkins Institute of
Medical Research. The annual
“speed networking” event is
designed to give first year dental
students the opportunity to connect
with alumni and explore professional
development and guidance as they
begin their career in dentistry.

Now in its fourth year, the Career Café
is proving to be a highly popular event
for both students and alumni. The         “I was surprised to learn
format of the event facilitates
conversation and connection between       just how many career
students and graduates via rotating       avenues there are in
seating positions in a set time frame.
                                          dentistry ranging from
First year DMD student Yasaman            private specialist care
Mishanini found the evening a great
opportunity to mingle with passionate     to general practice to
and charismatic dental alumni.            epidemiology,” she said.

Fourth-generation dentist graduates from UWA
Dr Grace Cooper recently graduated
with her Doctorate in Dental
Medicine. Dr Cooper’s great
grandfather graduated as a dentist in
1920, her grandfather in 1949 and her
Dad in 1979. Her family’s connection
to the profession greatly impacted
Grace’s decision to study dentistry.

“After getting the idea from my family,
 the more I learned about the
 profession, the more I was sure it was
 what I wanted to do”, Dr Cooper said.
                                          “I enjoy helping people, especially if it   Dr Cooper is now working in two Dental
A career in dentistry offers so many
                                           means getting them out of pain. The        Practices, Spearwood Dental Centre
opportunities, challenges and rewards
                                           satisfaction that I get from my job, for   and Harmony Dental in Morley. As a
and this is what attracted Grace to the
                                           example from winning over an anxious       new graduate, she is still enjoying
profession.
                                           patient to improving someone’s             exploring all the different aspects of
                                           confidence in their smile, at the end of   dentistry, especially aesthetic dentistry
                                           the day is truly rewarding”, she said.     and restorative dentistry.

10 The University of Western Australia
UWA dentist honoured for
work with disadvantaged
communities
UWA paediatric dentist Dr Jilen Patel    Dr Patel has continued to play an
has been named 2019 7News                active role in oral health advocacy
Western Australian Young Achiever        and developing oral health policy
of the Year and also awarded the         and practice for underserved
Masonic Care WA/Freemasons WA            communities.
Community Service and
Volunteering Award for his work          “We want to reach those
with vulnerable communities.
                                          people who have issues
Dr Patel is passionate about              accessing health care
improving oral health outcomes            and specifically dental care.”
among disadvantaged communities
and says his volunteering work           Dr Patel has also been involved
focuses primarily on children, as        with creating an integrated,
“their voices are often left unheard”.   multidisciplinary oral health
                                         education and prevention program
A graduate from the UWA Dental           for refugee children. His work has
School, Dr Patel is now a specialist     led to the implementation of an
paediatric dentist at Perth Children’s   Australian-first, randomised
Hospital and the Oral Health Centre      controlled clinical trial aiming
of WA. His journey was inspired by       to slow the progression of tooth decay.
mentor and UWA alumnus Dr John
Owen AM who is the founding director     “We have also translated the model
of the Kimberley Dental team and          of care to provide services to other
where Jilen is now a director and         vulnerable members of the
Senior Dental Officer.                    community, including homeless
                                          people in the metropolitan region,
The team provides voluntary dental        disadvantaged youth, refugees and
services to remote communities            aged care,” he said.
across the Kimberley region and
distributes tens of thousands of
toothbrushes and toothpaste to
Kimberley Schools.

                                                                                   uwa.edu.au/health 11
Connectivity, collaboration and opportunity
to generate healthy futures for our kids: UWA
Health Campus and Perth Children’s Hospital
The first of many milestones was recently achieved by Western                         Hospital is a great example of the kind
Australia’s Perth Children’s Hospital (PCH) celebrating its first                     of partnerships that organically flourish
birthday, marking the move from Princess Margaret Hospital in                         through this unique colocation of
Subiaco to Hospital Avenue in Nedlands.                                               health and education facilities in Perth.

The close proximity of the UWA Health       Collaboration between clinical practice   Professor Roebuck has extensive
Campus next to WA’s specialist              and pedagogy creates a synergetic         experience in the treatment of children
paediatric hospital and trauma centre,      relationship between universities and     with renovascular disease and complex
and the wider Child and Adolescent          health services; a key to attracting      aerodigestive problems. One of his
Health Service, provides new                world-leading researchers and             major medical interests is paediatric
opportunities for advancing the health      teachers. Students across the Faculty     cancer. He was Radiology Chair of the
and wellbeing of children, while both       benefit from being surrounded by          International Childhood Liver Tumour
driving research success and teaching       working hospitals and internationally     Strategy Group (SIOPEL) for over
excellence.                                 renowned health organisations, having     15 years and appointed to Great
                                            the opportunity to be embedded in         Ormond Street Hospital, London in
 A unique feature of a health and           these facilities from early on in their   1999 to develop the Interventional
 medical sciences degree at UWA is the      studies; and gaining real world           Radiology service.
 location of the Health Campus on the       practical experience through hands on
 same site as the largest medical centre    training with leading researchers and     It is not only undergraduate and
 in the southern hemisphere, the Queen      clinicians.                               postgraduate students who are
 Elizabeth II Medical Centre. This centre                                             benefiting from this symbiotic
 houses two major public hospitals          The recent appointment of Derek           relationship. Professional education
– Sir Charles Gairdner and the Perth        Roebuck as Professor of Paediatric        opportunities for staff, alumni, higher
 Children’s Hospital.                       Radiology at UWA and Perth Children’s     degree and early career researchers

12 The University of Western Australia
A community approach is critical to answer some of
            the big questions around child and youth mental health.”

also excel through the use of shared      policy makers and funders to improve      “What’s different about Embrace is
state of the art research facilities,     the health, development and lives of       that we’re looking right from early
equipment, idea generation and            children and young people. Their           childhood through to early adulthood,
networking.                               Embrace initiative is Australia’s first    so that we can make sure to identify
                                          comprehensive research centre              mental health issues where they start,”
Cross cultivation of ideas from           focused on mental health in people         said Professor Carapetis.
academia to research and practice         from birth to 25 years of age.
helps translate science into positive                                               “We need early identification and
health outcomes enabling greater          Embrace will bring together                intervention strategies so kids can
knowledge, innovation and lifesaving      researchers, clinicians, service           enjoy a happy childhood and a
discoveries for children’s health.        providers and the community in             mentally healthy future.”
                                          a collaborative effort to find new
UWA researchers Associate Professor       strategies and tools to address           The growing relationship between the
Ashleigh Lin and Professor Helen Milroy   alarming rates of mental health           University community at the UWA
are another example of how this           issues in this age group.                 Health Campus and the Child and
synergistic relationship between clinic                                             Adolescent Health Service is proving to
and campus is driving innovation in       Director of Telethon Kids Institute,      have a significant impact on the future
child health research. Together, they     consultant paediatrician at Perth         of child health; whether it be through
are co-leading Embrace, a new             Children’s Hospital and UWA Professor     offering students a world-class student
Telethon Kids Institute mental health     Jonathan Carapetis said an initiative     experience and education or pioneering
initiative.                               like Embrace is unique because of its     groundbreaking research, the positive
                                          focus on early detection and              effects of this new health hub will
Telethon Kids is based at the Perth       intervention of youth mental              continue to create unique opportunities
Children’s Hospital and brings together   health issues.                            to advance the health and wellbeing of
community, researchers, practitioners,                                              children in WA and beyond.

                                                                                                       uwa.edu.au/health 13
80 percent of disadvantaged
families are not adequately
nourished
                     We need to understand more
                     comprehensively what stops
                     people moving out of poverty.”

A multidisciplinary study involving       “The 100 Families WA study provides us        The project was launched in May 2018
researchers at the School of               with the opportunity to understand not       and will continue until 2022, with a
Population and Global Health has           only the lived experience of poverty,        baseline study involving 400 families,
found two-thirds of disadvantaged          but also the policy and practice             and in-depth interviews with 100
families struggle to afford feeding        changes needed to significantly reduce       families. As part of the project, the lives
their children a balanced meal. Of         levels of poverty”.                          and experiences of 100 families will be
these families, adults had lower food                                                   followed over time to examine the
security than children, sometimes         “This research is important                   causes of entrenched disadvantage, its
sacrificing food or going hungry in                                                     impact and the factors that positively
                                           because the results will
order to feed their children.                                                           contribute to exit from deep
                                           provide a very robust                        entrenched poverty. A central tenet of
The 100 Families WA study, which aims      evidence base on which                       the 100 Families WA project is that
to understand disadvantage and             significant policy and practice              research takes place with families,
poverty, found around 80 per cent of                                                    rather than on them.
                                           decisions can be made.”
disadvantaged families did not have
stable access to food to meet their       100 Families WA is a collaborative            The project has received in-kind
nutritional requirements. These initial   research project between UWA and              support from all partners, seed funding
findings are part of a wider report of    eight not-for-profit organisations in the     from the Centre for Social Impact
the baseline findings due to be           community services sector including           supported by The Bankwest Foundation
released in August.                       Anglicare WA, Ruah Community                  and the School of Population and
                                          Services, Wanslea, Jacaranda                  Global Health. In 2018 the McGowan
Professor Colleen Fisher, Head of UWA’s   Community Centre, Centrecare,                 Government announced a $1.75 million
School of Population and Global           UnitingCare West, MercyCare, and              grant on behalf of Lotterywest for the
Health, said living with entrenched       WACOSS to complete the research.              100 Families WA project.
disadvantage had severe negative
social and health outcomes for            “The School of Population and Global
individuals and families.                  Health is well placed to be a part of this
                                           integral research because of our
                                           commitment to improve health and
                                           social outcomes. Reducing levels
                                           of poverty is central to this,” said
                                           Professor Fisher.

14 The University of Western Australia
Health Professions Education team and alumni.

Health Professions Education
celebrates 10 years of graduates
This year marks the tenth anniversary of Health Professions Education (HPE)
graduates. To celebrate this milestone, an alumni evening was held in May.
Over 40 current students, academics and alumni joined guest speaker
Ms Karen Bradley, Executive Director – Clinical Leadership and Reform from
the Department of Health to celebrate the success and growth of UWA’s HPE
division in the last 10 years.

In today’s healthcare education system,   industries including higher education
many involved in teaching are             institutions, public regulatory bodies,
practising clinicians who require         community and healthcare service
training as managers, teachers or         organisations.
policymakers. HPE at UWA has
developed a strong reputation locally     Head of Division, Professor Sandra Carr
and internationally for its expertise     said, “the evening was testament to the
incorporating innovative teaching and     fantastic success of our graduates and
learning methodologies, across a suite    their application of the knowledge and
of reputable face-to-face and online      practical training they received during
postgraduate courses and professional     their studies here. HPE is very proud of
short course programs.                    our strong worldwide alumni
                                          community and professional friends
HPE graduates have forged exciting        and it was lovely to celebrate this
careers as educators, researchers,        special milestone with our current
practitioners and clinicians, and have    community of students, alumni and
worked across diverse fields and          valued network.”

                                                                                                          uwa.edu.au/health 15
Hospital discharges to
‘no fixed addresses’ –
here’s a much better way
                                                                                               Hospital and human
                                                                                               costs are high

                                                                                               One of the most costly consequences
                                                                                               of homelessness for any city is the
                                                                                               burden on the health system. Although
                                                                                               mental and physical health issues can
                                                                                               contribute to homelessness, being
                                                                                               homeless also increases the risk of
                                                                                               many health problems. These include
                                                                                               psychiatric illness, substance use and
                                                                                               chronic and infectious diseases.

                                                                                               Across Australia, people who are
                                                                                               homeless are among the most frequent
                                                                                               presenters to emergency departments.
“Homelessness is one of the most intractable and complex problems                              Their rate of unplanned hospital
 facing cities around the globe,” says my colleague Dr Jim O’Connell                           admissions is high. The average stay is
 from the Boston Health Care for the Homeless Program (BHCHP). It is                           longer too.
 somewhat sobering to hear that Boston is now into its third ‘ten-year
 plan’ to end homelessness. Despite the success of Boston’s Housing                            All of this strains the resources of our
 First programs housing many people who have lived on the streets for                          public hospitals, as shown in our recent
 years, it has proven difficult to ‘turn off the homelessness tap’.                            analysis of data for homeless patients
                                                                                               seen at Royal Perth Hospital.
The reasons include the lack of                      affordable housing crisis and huge
affordable housing options and a                     public housing wait lists. Alarming        Globally and within Australia, pressure
systemic failure to break the cycle of               numbers of people are released from        is mounting on hospitals to shorten
people leaving the corrections system                Australian prisons to homelessness         stays in costly hospital beds. However,
without somewhere to live.                           each year.                                 post-discharge care via less costly
                                                                                               ‘hospital in the home’ programs is not
O’Connell spent a week in Perth in 2018              So while ending homelessness in            an option for patients with ‘no fixed
as a Raine Medical Foundation Visiting               Australia is a vital aspiration, which     addresses’.
Fellow at UWA. He recounts around half               needs to be backed by a coordinated
the people entering Boston homeless                  national strategy, multisectoral action   As a result, homeless patients face
shelters indicate that ‘a jail’ was where            and greater dedicated funding, our        either longer inpatient admissions or
they slept the previous night.                       cities also need to be better equipped    are discharged when too unwell for the
                                                     to deal with the health impacts and       challenges of living on the street – and
These are cautionary warnings for                    other consequences of homelessness        that in turn results in deteriorating
Australia, where concerted efforts to                until it can be eradicated.               health and many unplanned
end homelessness are up against an                                                             readmissions.

This article was originally published by Associate Professor Lisa Wood from the
School of Population and Global Health on The Conversation: theconversation.com/au
This article has been adapted for print with the author’s permission.

16 The University of Western Australia
Respite centres offer
a solution

An innovative solution to these
problems is the medical respite model
for homeless people. This originated in
the United States in the mid-1980s.

A respite centre enables people who are
homeless to recuperate after hospital in
a more home-like environment. Here
they can receive follow-up care, social
support and be linked to community
services and accommodation providers.

A more homely non-hospital
environment is a critical ingredient, as
hospitals can be traumatising for
homeless people. Many of them have
suffered violence, sexual abuse, neglect,
incarceration or other forms of trauma,
further compounded by the trauma of
                                              Associate Professor Lisa Wood participating in the Homeless Healthcare outreach program.
living on the streets. From the Boston
experience, therapy dogs, social
connection, recreational activities, art    Canada. Australia at present has                  housed. Linking people to a general
therapy and patient support groups are      two small examples, in Melbourne                  practitioner through Homeless
among the healing benefits that can be      and Sydney.                                       Healthcare will be a critical part of the
provided outside a hospital                                                                   model, as its GPs and nurses can
environment.                                In Melbourne, The Cottage is literally            provide primary care and follow-up in
                                            a cottage next to St Vincent’s Hospital           the community to avert future hospital
One of our reasons for bringing Jim         in Melbourne. It has six patient beds,            admissions.
O’Connell to Australia was to draw on       with an average stay of nine days.
his experience as a founder of the first                                                      As Dr Andrew Davies, of Homeless
medical respite centre for homeless         Tierney House is a 12-bed, short-stay             Healthcare, and I stressed recently in
people in the US. It began as a 25-bed      respite unit run by St Vincent’s Hospital         the MJA, the absence of safe and
facility in Boston in 1985 and now has      Sydney. Support and care is provided              secure housing lies at the core of the
124 beds. Sadly, the demand keeps           for around $400 a day. This is far                health disparities seen among people
growing – for every bed that becomes        cheaper than the average Australian               who are homeless. This is particularly
available, there are 20 calls from          hospital bed cost of $2,003 a day in              apparent when they are discharged
hospitals wanting a bed for homeless        2015-16.                                          from hospital before they are well
patients.                                                                                     enough to return to the streets.
                                            Perth is seeking to establish Australia’s
What facilities does                        first 20-bed medical recovery centre for         Just imagine trying to recover from a
Australia have?                             people who are homeless. It’s based              hospital admission without a safe place
                                            on the US respite care model, but with           to rest and sleep, nowhere to wash, no
The respite centre model has flourished     a sharpened focus on connecting                  secure storage for medications, not to
in North America, with over 70 in cities    people to housing and long-term                  mention poor access to nutritious food
across the US and a growing number in       health and other support to remain               and difficulty maintaining hygienic
                                                                                             wound care.

In 2019 as part of the WA Sustainable Health Review Final Report, the State Government announced funding for the
establishment and evaluation of a 20-bed medical respite centre to provide clinical care to homeless people who may
otherwise be admitted to hospital. This will be first medical recovery centre of its kind in the Southern Hemisphere.

                                                                                                                   uwa.edu.au/health 17
Can being born blind
 protect people from
 schizophrenia?

Researchers in the Schools of
Population and Global Health and
                                          “This research may have implications
Medicine have released a study that        for intervention in the future. If we can
provides compelling evidence
congenital/early cortical blindness
                                           understand what causes the protective
(when people are blind from birth or       effect and artificially reproduce this, we
shortly after) is protective against
schizophrenia.
                                           may be able to intervene early at a stage
                                           to minimise or prevent those symptoms
The unusual discovery has fascinated
scientists and may lead to a better
                                           that can lead to schizophrenia.”
understanding of what causes
schizophrenia – a question that has       “It’s very difficult to say what the exact   actually be enhanced in people
baffled scientists for decades.            mechanism is but we think that the          with congenital or early cortical
                                           protective effect for schizophrenia is      blindness.”
The researchers used data collected        related to some kind of compensatory
from health registers between 1980         cortical reorganisation in the brain        Professor Morgan said the research
and 2001 on nearly half a million          that’s happening in response to             had concentrated on people who
people in Western Australia and            having congenital or early cortical         were blind at birth or in their early
found no one with a diagnosis of           blindness,” she said.                       years because there was greater
congenital or early cortical blindness                                                 brain plasticity at that age and
developed schizophrenia.                  “As a result, some functions that are        greater potential for new neural
                                           impaired in schizophrenia may               connections to be formed.
Lead author Professor Vera Morgan
from the UWA Neuropsychiatric
Epidemiology Research Unit said they
also found no one with congenital or
early cortical blindness had
developed any other psychotic
illnesses.

“This leads us to think there is a link
 that must be explored,” she said.

Professor Morgan said that the brain’s
plasticity could be the link.

18 The University of Western Australia
Stepping forward with ease
                                                                                 expert supervision by the University’s
                                                                                 Surgery teaching staff and other visiting
                                                                                 podiatric surgeons.

                                                                                 The DPS is a unique program in
                                                                                 Australia, with no other university
                                                                                 offering similar training.

                                                                                 Associate Professor Cam Wareham,
                                                                                 Head of the Division of Podiatric
                                                                                 Medicine and Surgery within the
                                                                                 School of Allied Health said:

                                                                                 “The Podiatric Surgery clinic is a
                                                                                  distinctive feature of our facilities
                                                                                  which support the education of our
The UWA Podiatric Surgery clinic      podiatric technology, the clinic offers
                                                                                  Doctor of Podiatric Surgery students.
is a state-of-the-art surgery         the best possible care to patients. In
                                                                                  This first class facility enables them to
facility and the first of its kind    2019, the clinic has treated many
                                                                                  gain expert knowledge of many foot
in the southern hemisphere.           patients and performed a number of
                                                                                  and ankle problems and furthers their
Highly qualified and experienced      procedures both simple and complex.
                                                                                  understanding of the theoretical and
Podiatric Surgeons consult at the
                                                                                  practical aspects of foot surgery.
clinic, diagnosing and treating       Postgraduate students in the Doctor
a variety of foot and ankle           of Podiatric Surgery (DPS) course          The opportunity to comprehensively
conditions requiring surgery.         undertake a substantial portion of         train in our expert clinic is part of the
                                      their training in the clinic, having the   reason we continue to attract the best
With individual consulting rooms, a
                                      opportunity to treat patients under        students to our DPS course,” he said.
purpose-built operating theatre for
onsite day surgery and the latest

Medical students attend national
leadership conference
In May, a group of six Doctor of      The NDLS has long been regarded as         NLDS provides a unique and intimate
Medicine (MD) students attended the   AMSA’s most prestigious academic           forum to discuss issues integral to
National Leadership Development       event, with delegates having a unique      health, education, politics and
Seminar (NLDS) in Canberra.           opportunity to engage with medical,        leadership, and is designed to shape
Mudra Shah, Lianne Leung,             social, and political issues. This         the medical leaders of tomorrow, both
Mark Hoey, Jana Crous, Erin Hassett   year’s NDLS theme was “Passion             in a professional and personal context.
and Nicholas Leedman were             for Inspiration”.
supported by the Faculty to attend                                               Ranging from second to final year, each
the annual conference, organised      Insights into effective leadership,        of the Faculty’s student delegates were
by the Australian Medical Students’   problem solving strategies, sustainable    competitively chosen to attend the
Association (AMSA).                   leadership and attaining work life         conference on the basis of increasing
                                      balance were a prime focus of the          their future leadership capacity, and
                                      plenaries, panel discussions,              upskilling their leadership and
                                      workshops, projects breakouts and          teamwork skills.
                                      social events.

                                                                                                      uwa.edu.au/health 19
Mr Michael Cornwall and Professor Schlaich

50 per cent of people do not know
they have high blood pressure
Results of a recent study involving scientists from UWA and the Royal Perth                 High blood pressure is the biggest
Hospital Medical Research Foundation has revealed 50 per cent of Australians                contributor to cardiovascular death
living with high blood pressure do not realise they have it.                                and disease worldwide, affecting about
                                                                                            six million adult Australians and more
                                                                                            than a billion adults globally with the
The research was published in May              “Even though effective treatments for
                                                                                            figure forecast to reach 1.5 billion by
in the European Heart Journal                   this condition are widely available, only
                                                                                            2025.
Supplements and found of 3817 people            half of the people affected by it are
involved in the Australian component            being treated, and of those treated         35-year-old patient Michael Cornwall
of the study, 31.2 per cent had high            only 60 per cent are having their blood     has suffered high blood pressure but is
blood pressure and only half of them            pressure adequately controlled,”            among those to seek detection early
were aware of it. Of those who received         Professor Schlaich said.                    and now enjoys an improved lifestyle
treatment, 40 per cent still had blood                                                      after treatment.
pressure above the recommended
                                               “This tells us that the
level. People who smoked, drank                                                             Mr Cornwall said since the treatment,
alcohol or had cerebrovascular disease          majority of people                          his blood pressure had dropped from
were at greater risk of having elevated
                                                who have high blood                         140 over 90 to a more manageable 120
blood pressure.                                                                             over 80 mmHg.
                                                pressure may have
Australian study lead UWA Professor
Markus Schlaich, who holds the
                                                never had it measured                       “A lot of younger people think it’s
                                                                                             something that typically happens to
Dobney Chair in Clinical Research at            and are unaware of                           older people or people that aren’t
the Royal Perth Hospital Medical
Research Foundation said the results
                                                their condition.”                            active but I’m proof that it can happen
                                                                                             to young active people,” he said.
were alarming.                                                                              “Treatment is really easy and you can
                                                                                             still lead a normal, healthy life.”

20 The University of Western Australia
New collaboration to improve
treatments for cancer patients

The University of Western Australia has entered a new collaboration with Douglas Pharmaceuticals,
building on the work of researchers from UWA and the Telethon Kids Institute, to develop
immunotherapy treatments for cancer.

Cancer immunotherapy, including            The team pinpointed drug                        “Through the partnership
the use of checkpoint-blocking             combinations that would tip the                 we will be able to perform
antibody therapies, has shown              balance and achieve favourable,
                                                                                           crucial laboratory studies
remarkable results in recent years, with   long-lasting results.
many patients achieving long-lasting                                                       to optimise treatments and
results and the regression of their        One of the identified drug combinations         better understand why
cancer, approaching ‘cures’.               which is shown to have far greater              some patients respond to
                                           activity than the use of a single drug
                                                                                           immunotherapy while others
However, while the treatment is            on its own will be developed with
effective for some patients, others do     Douglas Pharmaceuticals with the aim            do not,” Dr Lesterhuis said.
not respond and the reasons for this       of progressing into a clinical trial in 2020.
are not yet properly understood.
                                           Dr Joost Lesterhuis said the                    “I think it is a fantastic example of how
Lead researcher Dr Joost Lesterhuis,       partnership was an exciting                     approaches from very different fields of
a medical oncologist and group leader      opportunity to translate highly                 science, in this case mathematics,
from the School of Biomedical Sciences,    promising research findings into                computer science and cancer medicine,
and his team, including Dr Anthony         the clinic, with the potential to make          can together give us unique new insights
Bosco, Systems Biologist at Telethon       meaningful improvements in the                  with the potential to provide new
Kids Institute, used a network analysis    treatment of cancer.                            treatments for people with cancer.”
method to look at how thousands of
genes connect with each other in a
cancer, and which needed to be
activated to respond positively to
immunotherapy.

                                                                                                              uwa.edu.au/health 21
Master of Pharmacy student wins
ThinkSwiss Research Scholarship

Master of Pharmacy student                  of the project is to form international
Alexander Gallo was recently                guidelines on biosimilars and how they
awarded the ThinkSwiss Research             should be dealt with.
Scholarship which will provide him
with financial support to undertake         “It’s a fantastic achievement for Alex to
a research internship in Switzerland.        be awarded the ThinkSwiss Research
                                             Scholarship. We are also very pleased
The aim of the scholarship is to             that another Pharmacy student,
promote and increase research                Chelsea Harben, will be completing her
opportunities in Switzerland and to          research at the University of Basel as
foster the exchange between Swiss            well. To have two students undertake
and Asia-Pacific universities.               their research internationally is very
                                             exciting,” said Assistant Professor Liza
“I’m extremely excited to be representing    Seubert, Head of Division of Pharmacy.
 UWA in Switzerland and am very
 thankful to all the staff in Pharmacy
 for helping me to succeed in the course
 and to receive this scholarship. It’s a    “The restructure of the Master of Pharmacy
 wonderful opportunity,” said Alexander.
                                             curriculum has provided a dedicated block
Alex will be based at the University         for students to undertake their research
of Basel in the Department of
Pharmaceutical Sciences where his
                                             projects. This has opened up opportunities
research will focus on biosimilar            for students to complete these projects
drugs. This will involve reviewing data
collected from 10 different countries to
                                             internationally.”
assess the current practices and laws
around biosimilars and their                Alex and Chelsea will be in Switzerland
interchangeability. The overall aim         for 11 weeks from 22 July to 4 October.

22 The University of Western Australia
Broadening Units: Graduates
ready for a changing world
This semester, the Faculty received       any other of UWA’s undergraduate           Issues In Women’s Health Across their
record enrolments for our popular         majors. The breadth of knowledge           Lifespan is another unit offered in
offering of broadening units.             this opportunity allows is a key           Semester 2 proving to be of keen
Students from the disciplines of          advantage of the unique UWA                interest to students. This unit
Commerce, Engineering, Science            course model.                              introduces students to diverse
and Arts joined health students                                                      contemporary issues in womens
to explore units in Life and Health       One of the most popular broadening         health such as basic advances in
Sciences.                                 units was Mental Health and Wellbeing      genetic mapping; advances in
                                          with a record enrolment of 250             assisted reproduction, and the impact
Australian and international employer     students last semester. Mental health      this has on women’s health issues.
groups continually emphasise a need       is one of the most important and
for graduates who have acquired a         topical facets of modern healthcare        Most students choose to take their
broader suite of ‘transferrable’ skills   and the focus of this unit is to provide   broadening units in the first and
that prepare them for employment in       students with an overall understanding     second year of their degree, which
a changing world.                         of mental health and wellbeing for         can lead to the discovery of interests
                                          themselves and others.                     and passions that will give them a
UWA’s flexible undergraduate course                                                  distinct advantage with potential
structure offers students the             Drugs That Changed the World is            employers or open up further avenues
opportunity to explore interests          another unit which continues to be         of study.
across a wide range of disciplines, in    very popular with students across the
addition to their primary major or        University, with a record number of
degree specific area of knowledge.        1000 enrolments in Semester 2, 2018.
                                          The content of this unit examines
For example, students studying the        both the future of drugs and some of
Bachelor of Biomedical Science can        the most important drugs that have
choose to learn a language, take a        impacted society and revolutionised
personal finance unit, or study units     medicine and healthcare.
from design, management,
economics, communications,
philosophy, environmental science or

Students have the opportunity to
complete at least four broadening units
throughout their undergraduate degree.

                                                                                                       uwa.edu.au/health 23
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