ERA PerMed Cluster event on Personalised Medicine with ITN funded projects Maria Cristina Nieto Garcia - European Commission

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ERA PerMed Cluster event on Personalised Medicine with ITN funded projects Maria Cristina Nieto Garcia - European Commission
ERA PerMed
Cluster event on Personalised Medicine with ITN funded projects
Maria Cristina Nieto Garcia
National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

National Health School, ISCIII, Madrid, Spain, 6-7th Nov 2019

                              Horizon 2020                  GRANT AGREEMENT
                                                            NUMBER — 779282 ERA PerMed
ERA PerMed Cluster event on Personalised Medicine with ITN funded projects Maria Cristina Nieto Garcia - European Commission
ERAPerMed – Content

   ERA PerMed

   JTC2018 (co-funded by EC)

   JTC2019

   Next calls: JTC2020 & JTC2021
ERA PerMed Cluster event on Personalised Medicine with ITN funded projects Maria Cristina Nieto Garcia - European Commission
ERAPerMed – Characteristics
                                                    19 EU countries
                                                    3 associated countries (to Horizon 2020)
                                                    Turkey, Norway, Israel
                                                    1 third country (Canada)
   32 Partners                                      5 regions; Saxony, Quebec,
                                   23 Countries     Lombardy, Navarra and Cataluña

   Coordination:                                    The biggest ERA Net in health

   Instituto de Salud Carlos III
    (ISCIII), SPAIN                 TIME FRAME: 1 December 2017 – 30 November 2022

                                    Joint Transnational Calls (JTCs)
                                    1 EU Co-funded Call  2018
               MAIN OBJECTIVES
                                    Up to 3 Additional Calls  2019, 2020, 2021
http://www.erapermed.eu/
ERA PerMed Cluster event on Personalised Medicine with ITN funded projects Maria Cristina Nieto Garcia - European Commission
Action Plan   SRIA
          Horizon 2020
   Call: H2020-SC1-2016-2017                                       https://www.
    (Personalised Medicine)                                        icpermed.eu/
    Topic: SC1-HCO-03-2017

 Foster the implementation of ICPerMed Action Plan and SRIA
  (Strategic Research and Innovation Agenda) by funding transnational
  research projects in the field of Personalised Medicine (PM)
 Alignment of regional and national PM research strategies and
  funding activities, promoting excellence, reinforcing the
  competitiveness of Europe and Canada and enhance the European
  collaboration as well as with countries beyond the European Union.
ERA PerMed Cluster event on Personalised Medicine with ITN funded projects Maria Cristina Nieto Garcia - European Commission
ERAPerMed

 Definition of Personalised Medicine:
   Stated in the Strategic Research and Innovation Agenda
   (SRIA) of PerMed, adopted from the H2020 advisory group*:
• “Personalised Medicine refers to a medical model using
  characterisation of individuals’ phenotypes and genotypes
  (e.g. molecular profiling, medical imaging, lifestyle data) for
  tailoring the right therapeutic strategy for the right person at
  the right time, and/or to determine the predisposition to
  disease and/or to deliver timely and targeted prevention.”

* European Commission. Advice for 2016/2017 of the Horizon 2020 Advisory Group for Social
  Challenge 1, “Health, Demographic Change and Wellbeing
ERA PerMed Cluster event on Personalised Medicine with ITN funded projects Maria Cristina Nieto Garcia - European Commission
ERAPerMed – Structure

             WP1 - COORDINATION & MANAGEMENT

        EC cofunded call               WP6 - ADDITIONAL
       WP2+WP3+WP4+WP5                NON COFUNDED CALLS

            WP 7 - STRATEGIC SUPPORT ACTIVITIES
External relationships, relationship with end users and patient
  representatives, sustainability and exploitation of results…
ERAPerMed – Structure
              EC cofunded call

          WP 2 - PREPARATION AND LAUNCH OF
                THE EU CO-FUNDED CALL

           WP 3 – EVALUATION & PROPOSAL
        SELECTION OF THE EU CO-FUNDED CALL

   WP 4 - FOLLOW UP AND MONITORING OF THE EU CO-
                  FUNDED PROJECTS

WP 5 - COMMUNICATION AND EXPLOITATION OF RESULTS OF
              THE EU CO-FUNDED CALL
ERA PerMed – cofunding scheme

    33% of the budget                                        Unit
      commitment         7,834,200 €     1,674,750 €         costs

     23,740,000 €                             Maximum EU
                                9,508,950 €   contribution
 Initial Financial Commitment
   of ERA PerMed Partners

EC cofunded                                                          Implementation
    call
                6,718,613 €                   2,790,337 €                 costs
ERAPerMed – Content

   ERA PerMed

   JTC2018 (co-funded by EC)

   JTC2019

   Next calls: JTC2020 & JTC2021
ERAPerMed – EU co-funded JTC 2018
               http://www.erapermed.eu/joint-calls/joint-transnational-call-2018/

                                                           19 EU countries
                                                           3 associated countries (to Horizon 2020):
                                                           Turkey, Norway, Israel
                                                           1 third country: Canada
30 Partners
                                     22 Countries          5 regions

Call Secretariat (JCS)                                                 Countries´ ex ante Budget
Instituto de Salud Carlos III                                                   26 M €
(ISCIII), SPAIN
                          Two step procedure
                          Launch: 14th February 2018
              Timeline:   Submission deadline for Pre-proposals: 10th April 2018
                          Submission deadline for invited Full-proposals: 26th July 2018
                          Expected start of granted projects: 2019 q1
Call calendar
  Preparation of the JTC2018                                                                                                           Validation of
                                         Survey on                                                                                    the call text by
                      Expert           participation /           First draft of        CAB response              (Pre-) Final version       the EC
First concept                                                                                                                          At least 30 days
                    consultation      advanced concept            the call text        on the call text             of the call text
                                                                                                                                      before launching

     April             June                  July                   August               September                       November        December

       2017
                                                                                                                                Final funding decision
 JTC2018                                                                                                                          in November 2018
                                             Submission                               Submission
     Pre-                                     deadline                        CSC       deadline                    Rebuttal
                      Launch                                                                                                     PRP meeting
 announcement                               pre-proposals                    meeting full-proposals                  phase

    December         February                    April                          June       July                      August         September

                              At least 60 days           Evaluation 1st stage                     Evaluation 2nd stage

       2017             2018

                Each proposal is allocated to 3 Peer Reviewers for evaluation.
ERAPerMed – EU co-funded JTC 2018
                                Scope of the call
      TOPIC: RESEARCH PROJECTS ON PERSONALISED MEDICINE – SMART COMBINATION   OF
      PRE-CLINICAL AND CLINICAL RESEARCH WITH DATA AND ICT SOLUTIONS

Each project proposal MUST address at least one module of both Research Areas 1 and 2.
ERA PerMed JTC 2018
           Central Eligibility
    A) Academia or research institutes;
    B) Clinical/public health sector
    C) (Industry) Private partners, e.g. SMEs

• Each consortium must involve at least 3 partners eligible
  for funding coming from 3 different countries.
• Project coordinator must be eligible to be funded
• The maximum number of partners per project is 6
  (7 if underrepresented)
• No more than two partners from the same country.
• No more than one partner with its own funding is allowed.
* Each FO has its own national/regional eligibility criteria
Partnering Tool
https://partnering.pt-dlr.de/ICPerMed
ERAPerMed – EU co-funded JTC 2018
Pre-proposal Coordinators and Partners per Country
ERAPerMed – EU co-funded JTC 2018
Pre-proposal Request of Funding per Country
ERAPerMed – EU co-funded JTC 2018
Type of Applicant Beneficiary Entity in Pre-proposals
ERAPerMed – EU co-funded JTC 2018
ERAPerMed – EU co-funded JTC 2018
             Facts and Figures
• Pre-proposal stage:
 • 159/143 submitted projects
 • 741 partners requesting to 30 funding organisations
 • 176.21 M € requested funding
 • 50 Pre-proposals invited to submit a Full proposal
 • 75 evaluators from institutions affiliated to 24 countries (25% females)
• Full proposal stage:
 • 50 submitted projects
 • 25 Proposals funded, 131 partners requesting to 21 funding organisations.
 • 28.27 M € requested funding
 • 23 evaluators from institutions affiliated to 15 countries
ERAPerMed – Content

   ERA PerMed

   JTC2018 (co-funded by EC)

   JTC2019

   Next calls: JTC2020 & JTC2021
ERAPerMed – non EU co-funded JTC 2019
          http://www.erapermed.eu/joint-transnational-call-2019/
                                                    17 EU countries
                                                    3 associated countries (to Horizon 2020):
                                                    Turkey, Norway, Israel
                                                    2 third countries: Canada and Egypt
30 Partners                                         6 regions (Saxony, Quebec, Lombardy,
                                22 Countries                   Navarra ,Cataluña and Tuscany
                                                    1 charity: AECC
Call Secretariat (JCS)
Agence National de la Recherche (ANR)
FRANCE                                                         Countries´ ex ante Budget
                                                                      31.42 M €
                           Two step procedure
                        Launch: 9th January 2019
                        Submission deadline for Pre-proposals: 7th March 2019
              Timeline:
                        Submission deadline for invited Full-proposals: 17th June 2019
ERAPerMed – non EU co-funded JTC 2019

                    Scope of the call

TOPIC: PERSONALIZED MEDICINE: MULTIDISCIPLINARY RESEARCH
TOWARDS IMPLEMENTATION

Each project proposal MUST address at least one module of
Research Area 3 and at least one module of Research Area 1 or 2.
Submitted pre-proposals – N° partners/coordinators
         BMBF/DLR                                                                                               97                                        22
                  ANR                                                                                      86                               14
                 FRRB                                          39                                                      25
                 GSRT                                               43                                               15
                   SRC                                                   49                                           3
              IT-MoH                               27                                            23
     ISCIII/AECC-FC                                      33                                           15
                  FWF                                     34                                 6
              DS-CAT                                      34                             4                                            Partner
            UEFISCDI                              26                                10
                                                                                                                                      Coordinator
                  AKA                        21                                13
                NCBR                              25                          3
           InnoFond                                26                          2
no funding request                                  27                         0
          CSO-MOH                      16                        9
                  RCN                   17                  3
                 CIHR                   17                 2
               SMWK               10                7
                NKFIH                14            1
                    GN             11           4
                  HRB               13           1
             TuscReg              10         3
           BMG/VDI                 11         2
        F.R.S.-FNRS               9        2
                  MSE            8       2
                 VIAA           7     1
            TUBITAK              8     0
                 FRQS           7     1
                  FNR          5 1
                 ASRT        3 2
                  CDTI        4 0
                         0                                      20                                40                        60   80                 100        120
Submitted pre-proposals – budget requested
         ASRT         567 000,00 €
         CDTI         823 802,00 €
     TUBITAK           939 300,00 €
         MSE            1199 175,00 €
         VIAA           1455 347,00 €
          FNR            1655 437,00 €
  F.R.S.-FNRS             1908 913,00 €
        NKFIH             2066 203,00 €
        FRQS               2205 592,00 €
     TuscReg               2357 042,00 €
         GN                  3121 934,00 €
    BMG/VDI                   3401 977,00 €
         HRB                  3442 102,00 €
    CSO-MOH                    3588 005,00 €
         CIHR                  3616 365,00 €
        NCBR                     4322 676,00 €
         RCN                         5109 993,00 €
     UEFISCDI                           5866 548,00 €
      SMWK                                6624 952,00 €
      DS-CAT                                7262 921,00 €
          AKA                                7636 561,00 €
ISCIII/AECC-FC                                  8608 192,00 €
    InnoFond                                     9168 782,00 €
        GSRT                                       9917 828,00 €
        FWF                                          10384 314,00 €
      IT-MoH                                              11104 420,00 €
         SRC                                                               16544 040,00 €
        FRRB                                                                   18174 737,00 €
         ANR                                                                                    24578 937,00 €
   BMBF/DLR                                                                                                                             38840 483,00 €
             0,00 €        5000 000,00 € 10000 000,00 € 15000 000,00 € 20000 000,00 € 25000 000,00 € 30000 000,00 € 35000 000,00 € 40000 000,00 € 45000 000,00 €
ERAPerMed –non EU co-funded JTC 2019
                   Facts and Figures
• Pre-proposal stage:
 • 196 submitted projects
 • 906 partners requesting to 30 funding organisations (27 own funding)
 • 216 M € requested funding
 • 56 Pre-proposals invited to submit a Full proposal
 • 102 evaluators from institutions affiliated to 26 countries (33% females)
• Full proposal stage:
 • 56 submitted projects
 • 22 Proposals expected to be funded, 108 partners requesting to 24
   funding organisations (5 partners on own funding).
 • 24.6 M € requested funding
 • 29 evaluators from institutions affiliated to 17 countries
ERAPerMed – Content

   ERA PerMed

   JTC2018 (co-funded by EC)

   JTC2019

   Next calls: JTC2020 & JTC2021
ERAPerMed – non EU co-funded JTC 2020

                                                                17 EU countries
                                                                2 associated countries (to Horizon 2020):
                                                                Norway, Israel
                                                                3 third countries: Canada, Egypt, Panama
                                                                6 regions (Saxony, Quebec, Lombardy,
         31 Partners                          22 Countries                   Navarra, Cataluña and Tuscany)
                                                                1 charity: AECC
         Call Secretariat (JCS)
         German Aerospace Center (DLR)
         GERMANY permed@dlr.de                                         Countries´ ex ante Budget
                                                                           24.6 M € approx.

                                  Two step procedure
                                Launch: December 2019
             Timeline expected: Submission deadline for Pre-proposals: March 2020
                                Submission deadline for invited Full-proposals: June 2020

http://www.erapermed.eu/wp-content/uploads/2019/11/ERA-PerMed_JTC2020_pre-announcement_final.pdf
ERAPerMed – non EU co-funded JTC 2020

                     Scope of the call
  TOPIC: “PERSONALISED MEDICINE – PRE-/CLINICAL RESEARCH, BIG
  DATA AND ICT, IMPLEMENTATION AND USER’S PERSPECTIVE”

  Each project proposal MUST address at least one module of
  Research Area 3 and at least one module of Research Area 1 or 2.
ERAPerMed – Joint Call Secretariat contact points

   JCS2018: ISCIII- Mauricio García, Candi Sánchez and Cristina Nieto:

    eranetpm@isciii.es

   JCS2019: ANR- Monika Frenzel and Jeanne Guihot

    ERAPerMed@agencerecherche.fr

   JCS2020: DLR- Katja Kuhlmann and Alexandra Becker

    permed@dlr.de
Thank you for your attention!
Contact: Maria Cristina Nieto Garcia, PhD    

                             GRANT AGREEMENT
      Horizon 2020
                             NUMBER — 779282 ERA PerMed
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