"WE WILL STAY AHEAD OF THE TREND" - INGREDIENTS New ingredients for skin brightening p 22 - COSSMA

 
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"WE WILL STAY AHEAD OF THE TREND" - INGREDIENTS New ingredients for skin brightening p 22 - COSSMA
www.cossma.com | E51280                          4/2020

                                 INGREDIENTS
                                 New ingredients for
                                 skin brightening
                                 p 22

                                 GREEN CONCEPTS
                                 How much PCR is
                                 possible?
                                 p 36

                          “WE WILL STAY
                          AHEAD OF THE
                          TREND”
                          Ulrich Issberner, Director
                          Marketing Personal Care BASF
                          p 56
"WE WILL STAY AHEAD OF THE TREND" - INGREDIENTS New ingredients for skin brightening p 22 - COSSMA
Naomi, Anne and Marion
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Their stories. Your products.
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Plantacare ® range – now celebrating 25 years of outstanding
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Every story matters.
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Visit us at in-cosmetics 2020 in Barcelona
March 31 to April 2, booth K50
"WE WILL STAY AHEAD OF THE TREND" - INGREDIENTS New ingredients for skin brightening p 22 - COSSMA
EDITORIAL

Focus on health!

E
      ven if you are not directly affected, unfortunately you can no longer close               FOLLOW COSSMA ON:
      your eyes to the Coronavirus. It has arrived in many countries and is taking
      on ever larger dimensions. Even if the disease is mild, it is still important to
be careful and take the necessary precautions; I try to protect myself with the right
hygiene measures. Industrial hygiene also plays an important role in the cosmet-
ics industry and must evolve continuously. Starting p 42, Joelle Nussbaum speaks                    www.cossma.com
about the latest book on the subject.

Precaution also includes the cancellation of spring trade fair dates, however compli-
cated it may be for everyone involved. Ultimately, this is a goal we strive for in our
                                                                                         www.linkedin.com/company/cossma-digital
daily work: the health and well-being of all: customers, employees, suppliers and
other business partners. With this in mind, I welcome the decision to postpone trade
fairs in order to slow the spread of the virus.

I wish you all the best.
                                                                                            www.twitter.com/cossmamagazine

Stay healthy!

                                                                                                www.youtube.de/cossmatv
Sincerely yours,

Georg von Griesheim,
Managing Director

                                                                                                            www.cossma.com    l3
"WE WILL STAY AHEAD OF THE TREND" - INGREDIENTS New ingredients for skin brightening p 22 - COSSMA
Contents
COSSMA 4/2020

                       8	MARKETS &                          16 Interview with Josefine
                                                                Schroeder, BTC Europe:
                          COMPANIES                             Waterfree challenge
                          08 News                            18 Michelle Strutton, Mintel:
                                                                International product
                                                                launches
                       10	GO FUTURE:
                           BODYCARE
                          12 Gabriella Beckwith,
                                                          20 INGREDIENTS
                             Euromonitor: Disruptive or      22 Shyam Gupta, PhD, Bioderm
                             innovative?                        Research: Natural skin
                                                                brightening
                                                             26 Dr Natascia Grimaldi,
                                                                Patricio Gabarrón, Infinitec

                               26   Unlocking
                               more potential
                                                                Activos: Unlocking more
                                                                potential
                                                             28 Formulations: Masks
                                                             30 News Ingredients

                                                          32 GREEN CONCEPTS
                                                             34 Elfriede Dambacher,
                                                                Naturkosmetik Konzepte:
                                                                Green is growing
                                                             36 John Ferro, Silgan
                                                                Dispensing:
                                                                Using recycled materials

4l   COSSMA 4 I 2020
"WE WILL STAY AHEAD OF THE TREND" - INGREDIENTS New ingredients for skin brightening p 22 - COSSMA
10–18
                                Current developments
                                with body care

                                                                48       Experts in precision

                                              42  Joelle Nussbaum,                              SERVICES
                                                 BAV Institute: Be more
                                                                                                  3 Editorial
                                                 sensitive for hygiene
                                                                                                  6 Download List
                                                                                                61 Events Diary
                                         44 PACKAGING                                          62 Suppliers‘ Guide
                                              46 Isabelle Louis, Arcade Beauty:                 65 Advertisers’ Index
                                                 Producing more ecologically                    66 Preview/Imprint

                                              48 Rosa Porras Mansilla, Viro-
                                                 spack: Experts in precision
                                              51 News Packaging
                                              53 Review PCD

                                         55 PERSONALITIES &
                                            PROFILES
 40   Managing deviations
                                              55 News: Personalities & Profiles
                                              56 Interview with Ulrich Issberner,
                                                 BASF: Setting Trends for 25 years

38 MARKETING
   40 Dr Klaudia Brysch, Michael
                                         58 EVENTS
      Pfeiffer, Pfeiffer Consulting:          58 Imogen Mathews, In-Cosmetics:
                                                                                                Front cover picture:
      Managing Deviations                        Marketing trends                               Ulrich Issberner, BASF

                                                                                                                         www.cossma.com   l5
"WE WILL STAY AHEAD OF THE TREND" - INGREDIENTS New ingredients for skin brightening p 22 - COSSMA
SERVICES

                   Free Downloads
                   for subscribers | www.cossma.com/download

       CLICK THROUGH OUR WEB TV CLIPS: WWW.COSSMA.COM/TV

SIMONA ANTONINI                                     DR ADOLF KLENK                                      DOMINIKA MINAROVIC AND
R&D BolognaFiere, Cosmoprof                         Head of Research, Dr Kurt Wolff                     ELSIE RUTTERFORD
about an entire production cycle of a               about the latest findings in the effects            Co-Founders, BYBI Beauty
product that is sustainable.                        of caffeine.                                        about their products and why these are
                                                                                                        unique.

ALESSANDRO PRESTINI                                 SAM FARMER                                          JULIETTE SICOT-CREVET
CEO of Premi                                        Founder of the eponymous brand                      VP Business, Development Naturals
about customisation andaward-                       about his brand that offers unisex alter-           and Sustainability, Firmenich
winning creations .                                 native products for teenagers.                      about the company’s achievements in
                                                                                                        sourcing sustainable ingredients.
                                                                                                                                                       photo: Kiuikson, Shutterstock.com

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On the COSSMA website, we post lots of additional information related to the topics covered in the magazine. You will find more than 1,000
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cover; market data and statistics; supplier listings; literature references; scientific articles; product formulations and useful base formulations.
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6 l COSSMA 4 I 2020                                                                                                                  www.cossma.com
"WE WILL STAY AHEAD OF THE TREND" - INGREDIENTS New ingredients for skin brightening p 22 - COSSMA
Amaze™ Nordic Barley
Beautifying by nature

The sustainably sourced barley starch is produced without
the need of chemical modification and enables clean-
labeled cosmetic products, speaking in particular to
today’s eco-conscious consumers.

Amaze Nordic Barley, a 100% natural visual and sensorial
formulation enhancer, reduces shine and greasiness of
sun and skin care formulations. It delivers excellence
on-hair feel and removability from low whitening dry
shampoo conditioners.

Request a sample today at
personalcare.marketing@nouryon.com

Visit us at nouryon.com/personalcare for more product
information.
"WE WILL STAY AHEAD OF THE TREND" - INGREDIENTS New ingredients for skin brightening p 22 - COSSMA
MARKETS & COMPANIES

News
Multiple award-winning
employer
                                                                       Back to
                                                                       Cologne
                                                                                                            LESS EMISSIONS
AKZONOBEL | This year marks the company’s first “Top                   MACK BROOKS |
Employer” certifications in both the Netherlands and                   Chemspec Europe, the
the US. With eight consecutive years in the UK, seven in               international exhibition
China and four in Brazil, AkzoNobel continues to build on              for fine and speciality
its strong track record of people-driven initiatives. Work-
ing environment, company culture and benefits are some
of the topics considered in the rigorous review by the Top
Employers Institute.
www.akzonobel.com                                                                                           To safe nature, Metsä Board works
                                                                                                            hard to reduce emissions.

                                                                                                            METSÄ BOARD | The producer of
                                                                                                            premium fresh fibre paperboards, got its
                                                                       Chemspec Europe                      emissions reduction targets approved by
                                                                       returns to Cologne.                  the Science Based Targets initiative as
                                                                                                            being consistent with the levels required
                                                                       chemicals, returns to Co-            to meet the goals of the Paris Agreement.
                                                                       logne for its 35th edition.          The Science Based Targets initiative (SBTi)
                                                                       From 27 – 28 May 2020,               is a collaboration between CDP, the
                                                                       renowned manufacturers               United Nations Global Compact, World
                                                                       and suppliers present                Resources Institute (WRI) and the World
                                                                       their latest products, ser-          Wide Fund for Nature (WWF).
                                                                       vices and research find-             www.metsaboard.com

                                                                       ings to a dedicated audi-
For AkzoNobel it is crucial for the business                           ence of industry experts.
to treat the employees with respect.                                   www.chemspeceurope.com

INVESTMENT
PIRAMAL GLASS | The global specialist in design, production and decoration of niche glass
packaging announces an investment of US$ 42 Million in its greenfield project in Jambusar,
Gujarat, India. The expansion plan includes one new furnace with seven new manufacturing
lines. A plant catering primarily to high-end specialty spirit, food and beverage and pharma-
ceutical markets primarily for exports to countries in Asia, Europe and the US.                             Mr. Vijay Shah (in front), Vice Chairman, Piramal
www.piramalglass.com                                                                                        Glass Ltd at the Groundbreaking Ceremony.
                                                                                                                                                                photos: Akzo Nobel, Mack Brooks, Metsä Board, Piramal Glass, Optima

                                                                                             Positive annual report
                                                                                             OPTIMA | The packaging group has closed out 2019
                                                                                             with a total turnover of more than 400 million euros.
                                                                                             Optima generated more than 85 percent of its sales
                                                                                             abroad with 2,450 employees working around the
                                                                                             globe. Since March 2019, the group has a new subsid-
                                                                                             iary – Rianta Packaging Systems. The inauguration of
                                                                                             the CSPE Center and the logistics center last year set
                                                                                             out Optima’s strategy for the future. For the company,
In July 2019, Optima officially inaugurated the new logistics center                         2020 is all about Interpack.
with its new infrastructure and cutting-edge IT technology.                                  www.optima-packaging.com

8l   COSSMA 4 I 2020                                                                                                                        www.cossma.com
"WE WILL STAY AHEAD OF THE TREND" - INGREDIENTS New ingredients for skin brightening p 22 - COSSMA
RUBRIKTITEL

                                                                                                                                                           News

                                                   Stephenson invested in production methods to
                                                   strengthen the personal care division.

                                                   Investing in production methods
                                                   STEPHENSON | The soap base and speciality ingredients
                                                   manufacturer Stephenson is continuing to expand by
                                                   investing in production methods at its UK headquarters. The
                                                   family-owned business has invested over £750,000 in upgra-
                                                   ding its Durosoft production facilities, with the objective of
                                                   producing more technically advanced and improved natural
                                                   products. Stephenson delivers tailor made solutions for per-
                                                   sonal care brands and manufacturers worldwide.
                                                   www.stephensonpersonalcare.com

                                                                                                                           S K I N M I C R O B I O TA
                                                                                                                           The invisible key to beautiful skin

                                                                                                                                 Scientific discoveries for innovative
                                                                                                                                 dermocosmetic concepts

                                                                                                                                 Microflora balancing cosmetics
                                                   Dubai to strengthen status as regional beauty capital
                                                   at the 25th edition of Beautyworld Middle East.
                                                                                                                           Discover our new active ingredients:
                                                   BIG EVENT FOR A                                                               Balance skin microbiota
photos:: Stephenson, Messe Frankfurt Middle East

                                                   STRONG MARKET                                                                 Support beneficial bacteria
                                                   MESSE FRANKFURT MIDDLE EAST | Hosting more than                               Protection of skin microflora
                                                   1,800 exhibitors across six product segments the 25th edition
                                                   of Beautyworld Middle East will run from 31 May to 2 June
                                                   at Dubai World Trade Centre. Leading distributors of beauty
                                                   brands are eyeing up the Middle East market which has been
                                                   tipped to grow by 6.4 per cent (CAGR) over the next five
                                                   years.
                                                   www.beautyworldme.com                                            Distributed by
                                                                                                                    IMPAG Import GmbH
                                                                                                                    Fritz-Remy-Straße 25             IMPAG Group Country Offices
                                                                                                                    D-63071 Offenbach am Main        Switzerland / Zurich – www.impag.ch
                                                                                                                    Phone: + 49 (0) 69 850 008 - 0   Germany /Offenbach – www.impag.de
                                                                                                                    Fax: + 49 (0) 69 850 008 - 90    France / Nancy – www.cossma.com
                                                                                                                                                                      www.impag.fr    l  9
                                                                                                                    E-Mail: kosmetik@impag.de        Poland / Warsaw – www.impag.pl
                                                                                                                    Web: www.impag.de                Austria / Vienna – www.impag.at
"WE WILL STAY AHEAD OF THE TREND" - INGREDIENTS New ingredients for skin brightening p 22 - COSSMA
10 l COSSMA 4 I 2020
   www.cossma.com
                       photos:VGstockstudio/Shutterstock.com
                       photo:  Lucky Business/Shutterstock.com
GO FUTURE

Bodycare
Disruptive or innovative?���������������������������������������������������������������������������p 12
Waterfree challenge ���������������������������������������������������������������������������������p 16
International launches ���������������������������������������������������������������������������� p 18

                                                                                                www.cossma.com   l 11
Disruptive or innovative?
Markets | Having high market shares now is no longer a guarantee for playing a
leading role in personal care in future. Gabriella Beckwith explains, how renovators,
innovators and disruptors assert their influences.
                                                                                                                                                   photos and figures: author; anon_tae/Shutterstock.com

                                                                 U
                                                                         oday’s leading beauty brands     comers really disruptive? This article
                                                                         are increasingly under threat    explores disruption in the context of
                                                                         from smaller disruptive play-    emerging beauty and personal care
                                                                 ers. New opportunities, arising from     brands, with a focus on Europe, the
                                                                 changes in consumer behaviour, are       Middle East and Africa. It delves into
                                                                 now often being met by new,              beauty innovators in local markets
                                                    AUTHOR:      fast-growing insurgent brands or lo-     that have identified and catered to a
                          Gabriella Beckwith, Senior Analyst –
                       Beauty & Fashion, Euromonitor, London,    cal businesses with a closer connec-     gap in their market and evaluates
                       United Kingdom, www.euromonitor.com       tion to their customers. Are these up-   how disruptive these brands are

12 l COSSMA 4 I 2020                                                                                                              www.cossma.com
GO FUTURE: BODYCARE

                                                                       We
                                                                       encourage
                                                                       all kinds
                                                                       of beauty.

                                                                  C

                                                                  M

                                                                  Y

                                                                 CM

                                                                 MY

                                                                 CY

                                                                 CMY

                                                                  K

within their local market. With the word ‘disruption’ being
so influential today across so many industries, Euromonitor
has built a framework around the concept, in order to help
identify and explain what disruption is.
Renovation has a main purpose of re-establishing a brand
within the category it has traditionally served. Innovation is
more transformational, leading to the creation of new sub-
categories.
Lastly, disruption is where a company invents an entirely new
category or market. It is about reconceptualising the market,
creating consistent engagement and being consumer-centric,
often delivering a product or service that meets needs con-
sumers weren’t even aware they had. It’s about leading fear-
lessly, acting boldly and quickly, and not being tied down by
layers of bureaucracy.
While renovation and innovation help companies and indus-

                                                                                      We
tries to evolve, disruption is transformative.
So, who has the power to disrupt? Essentially the answer is
anyone, but Euromonitor has divided that into three catego-
ries
• Insurgents: Small but dynamic, fast-growing brands who
                                                                                      believe that
   tend to steal market share from bigger players.
                                                                                      taking care
                                                                                      is taking
                                                                                      action.
GO FUTURE: BODYCARE

NN EXAMPLES OF LOCAL INNOVATIVE                          • Incumbents: Well-known large            cal brands, disruption has been
   BRANDS FROM ­WESTERN EUROPE:                            multinationals who already hold         slower to take off, particularly as
                       Renovator: Bilou, Germany           significant market share and re-        markets such as Russia and the
                       A vegan hair care and shower        sources, often using incubation as      Ukraine remain characterised by
                       range launched by popular           a strategy when aiming to dis-          price-sensitive consumers due to
                       German YouTuber Bianca              rupt.                                   fluctuations in disposable income.
                       Claßen, offering diverse          • Local brands: Brands that disrupt       Skin care has experienced the big-
                       ­flavours such as ‘Tasty            on a local scale in their home          gest surge in innovative brands,
                        Doughnut’.                         market, due to their close connec-      boosted by demand for high-quality
                                                           tion to consumers.                      natural brands. Compared to West-
                       Innovator: Beautonomy,                                                      ern Europe, the natural trend is at
                       UK                                Market in Western Europe                  an earlier stage of development,
                       Face and eye palettes. Custom-    The top five beauty and personal          meaning opportunity remains for
                       ers can personalise both the      care players in Western Europe make       niche natural brands to enter the
                       product and the packaging         up 38% of the total market value.         scene.
                       used and then sell the end        Most of the top players have experi-      In Hungary for example, Deciem’s
                       result on the Beyutonomy mar-     enced flat or declining value share       The Ordinary saw a powerful debut
                       ketplace for commission.          in recent years, under the emergence      in 2018, known for its simple formu-
                                                         of smaller insurgent brands ap-           lae and ingredient transparency.
                       Disruptor: Lesielle, Spain        proaching consumers directly with         Niche unisex fragrances are also per-
                       Personalised skin care at an      “authentic” messaging and unique          forming well, particularly among af-
                       affordable price. Lesielle’s      product propositions.                     fluent Eastern European consumers
                       device allows consumers to        Multinationals are being challenged       searching for more authenticity and
                       make their own skin care at       by newcomers responding to de-            individuality.
                       home, adapting to individual      mand for natural and efficacious          Internet retailing is also gaining mo-
                       needs on different days.          beauty products, success stories in-      mentum in Eastern Europe, again
                                                         cluding Germany-based Dr Barbara          boosting the rise of niche brands.
                                                         Sturm and UK’s The Inkey List.            This is particularly key in larger mar-
                                                         Colour cosmetics also faces pressure      kets, where the in-store availability
                                                         from smaller disruptors. In Euro-         of smaller brands in remote areas is
                                                         monitor’s Beauty Survey, the per-         limited. Czech based online retailer
NN EXAMPLES OF LOCAL INNOVATIVE                          centage of respondents in Europe          Notino has been expanding its pres-
   BRANDS FROM THE MIDDLE EAST                           who would prefer an “on-trend,            ence, launching into Russia in 2019,
   AND AFRICA:                                           new-to-me brand” colour cosmetics         while Sephora also launched into
                       Renovator: Joviality, Egypt       brand over a previously used brand,       Russia last year, increasing the avail-
                       Products are made from 100%       has increased year on year since          ability of niche brands.
                       natural ingredients. They are     2015.
                       produced in Egypt, and contain    Drugstores have performed well in         Markets in Middle East
                       inter-esting flavours such as     the last years, fuelled by retailers      and Africa
                       Apple Cinnamon and Ylang          enhancing their beauty offerings.         Among all regions, the Middle East
                       Ylang.                            Boots in the UK revamped its beauty       and Africa is the most fragmented.
                                                         sections, while German drugstore          Disruption in the region is diverse,
                       Innovator: Portia M,              dm launched its private label brand       predominantly due to differences in
                       South Africa                      183 days, bringing new innovations        ethnicities, beauty standards and in-
                       Caters to the skin care chal-     to market every 183 days to target        come levels. Domestic players tend
                       lenges faced by African           young experimental consumers.             to have a large presence, with the
                       women. Contains locally           Internet retailing is the fastest grow-   top five beauty and personal care
                       sourced Marula oil a familiar     ing channel in the region, driven by      players contributing just 30% of to-
                       ingredient passed down            beauty retailers such as Feelunique       tal value sales in the region.
                       through generations..             and Cocopanda, and online giants          Hair care is the largest and most dy-
                                                         Amazon and Zalando, all of which          namic category here. African con-
                       Innovator: Fré, Israel            are expanding their beauty offers.        sumers are turning towards smaller
                       Products are formulated specif-                                             niche brands that can offer person-
                       ically for wom-en who work        Market in Eastern Europe                  alised products, due to the feeling
                       out, with the unique position-    The top five beauty and personal          that multinationals fail to offer prod-
                       ing “sweat beautifully”. Prod-    care players in Eastern Europe make       ucts suited to one’s individual hair
                       ucts are also 100% vegan and      up 35% of the total market. Despite       type. Similarly, tailor-made skin care
                       cruelty free.                     a growing interest for niche and lo-      and colour cosmetics brands are

14 l COSSMA 4 I 2020                                                                                                       www.cossma.com
GO FUTURE: BODYCARE

NN EXAMPLES OF LOCAL INNOVATIVE
   BRANDS FROM EASTERN EUROPE:
                   Renovator:
                   Beauty Bomb, Russia
                   Bright, bold and affordable
                   make-up, targeting a digital-
                                                                                  35th International Exhibition for
                   ly-savvy younger audience.                                      Fine and Speciality Chemicals
                   Strong use of online promotion,
                   with the brand philosophy
                   being beauty without rules.                                        Koelnmesse, Cologne, Germany
                   Innovator:
                                                                                                            27 – 28 May 2020
                   One Ingredient, Poland
                   High-quality natural products
                   with minimalistic formulas, fea-
                   turing a high content of snail
                   slime, the active ingredient.
                   Interesting packaging design
                   and ecological approach.

                   Disruptor: [n]fibrecare,
                   Czech Republic
                   The first Czech high-tech dry
                   sheet face masks, made with
                   nanofibres. The brand’s
                   ground-breaking technology
                   has generated much media
                   attention.

                                                                   Europe’s No 1 trade fair
                                                                   for the fine and speciality
  gaining popularity, especially those catering to African com-
  plexions, such as Pauline cosmetics in Kenya. Fragrances         chemicals industry
  have traditionally been engrained in the culture of many
  Middle Eastern countries. Niche luxury scents are contin-       Chemspec Europe 2020 is the place to be: Find bespoke
  uing to grow in the region, with well-known brands like         solutions & innovative substances for your enterprise and
  Huda Beauty.                                                    take your networking to the next level
  Supermarkets dominate the region’s beauty landscape,
  while internet retailing does not even fall into the top six    • custom synthesis
                                                                  • pharmaceuticals                         Top conferences and workshops
  channels. The presence of online retailing is much stronger
                                                                                                            offer valuable insights into
  in the Middle East. We can expect changes as technology         • fine chemicals                          ongoing R&D projects!
  advances and social media’s influence rises. Already in         • chemical intermediates                   Agrochemical Lecture Theatre
  South Africa we are seeing changes, such as Superbalist,
                                                                  • agrochemicals                            Chemspec Careers Clinic
  who recently launched a beauty shop on their website.
                                                                  • paints & coatings                        Pharma Lecture Theatre
  These local brands draw success from their ability to trade
  on local knowledge, understand the needs of their local         • green chemicals                          Regulatory Services
  consumers, and create something unique to their home            • household & industrial                   Lecture Theatre
  market. Looking back at the framework, renovation and             cleaning                                 RSC Lecture Theatre
  innovation help companies and industries to evolve,             • bio-based chemicals                      Innovative Start-ups
  through novel formats, ingredients, new ways of engaging        • biocatalysts
  with consumers and so on.                                       • cosmetics
  While disruption is meant to be transformative, it’s about
                                                                  • electronic chemicals
  creating real value for the consumer, and meeting needs
                                                                  • and much more
  they might not have been aware they had. Disruptors see
  beyond the rules of the market and put consumers at the
  centre of everything they do.                             Q

                                                                  Get your ticket now:
                                                                  www.chemspeceurope.com
                                                                  Organisers: Mack Brooks Exhibitions Ltd
GO FUTURE: BODYCARE

              waterfree Challenge
                                                                                                              Inter view

               Ingredients | In order for meet consumers’ demand for zero-waste
               products, waterfree formulations have become a sustainable alternative
               in personal care. Josefine Schroeder explains the rapid development.

             NN Josefine Schroeder,              COSSMA: In the last years water-         significantly contributed to the
                                                                                                                                   fotos: author, Ellistar/Shutterstock.com

                  Senior Technical Expert        free formulations have become a          greater use of waterfree formulations.
                  ­P­ersonal Care, BTC Europe,   growing trend in the personal care       With a world population projected to
                   Monheim am Rhein, Germany,    industry. Why?                           reach the mark of 10 billion by 2050,
                   www.btc-europe.com                                                     water will become an even scarcer
                                                 Josefine Schroeder: The growing in-      source. As a result, companies in the
                                                 terest in sustainable products and the   personal care industry have been
                                                 increasing awareness for re-             looking into new ways to reduce wa-
                                                 source-friendly technologies have        ter consumption while at the same

16 l COSSMA 4 I 2020
GO FUTURE: BODYCARE

time finding innovative solutions to         ter and that are easy o process. We
meet the increasing demand for skin          also used different types of sur-
and hair care products.Figures from          factants in order to obtain optimal
the year 2019 show that in Germany,          foaming and cleansing while mini-
for example, consumers spent 3.3 bil-        mising skin sensivity and abrasion.
lion Euros on skin and face care –           The balance between the different
3.3% more than in 2018. We experi-           ingredients’ ratios in the formulation
ence a rising demand with our                is crucial for the outcome.
customers in the last years, especially
for personal care products wich are          Which ingredients are best, and
more sustainable.                            which are less suitable?                  All ingredients of solid products should
Waterfree formulations without en-                                                     have a high level of solubility in cold water.
vironmentally harmful packaging              All ingredients should have a high
have therefore become a suitable al-         level of solubility in cold water. In
ternative in the personal care indus-        addition, a surfactant like Sulfopon
try. At BTC Europe, we are already           1214 G is well suitable for waterfree
offering our customers waterfree             formulations due to its good cleans-      Equally important is the abrasion of
product solutions. Our recent product        ing and foaming performances. Cat-        the product, for example: soap bars.
collection – our Solid Collection – for      ionic conditioning agents like De-        If the consistency of the final bar is
example, has been created in coop-           hyquart A-CA are well suited for          too firm, the cleansing effect is di-
eration with our colleagues from             achieving better combing.                 minished. Here, the mixture of differ-
BASF and was presented at the last           Waxes with a high melting point are       ent waxes generates the right amount
Sepawa in Berlin. The idea was to            highly effective since they are resist-   of abrasion.
create a collection of products based        ant to high temperatures. This prop-      When producing hair care products
on waterfree formulations such as            erty is extremely important for prod-     like shampoo bars, cationic condi-
easy foaming shampoos, solid condi-          ucts distributed mainly in southern       tioning agents are essential to an ef-
tioners, cream shower bars and more.         countries where higher outside tem-       fective formulation. Since human
                                             peratures prevail. Cegesoft HF 62, for    hair is negatively charged, cationic
                                             example, is a cosmetic wax compo-         conditioning agents are indispensa-
                                             nent consisting of hydrogenated veg-      ble delivering a good combing per-
                                             etable oil that is used as solid emol-    formance.
                                             lient and for the stabilisation of many
                                             solid products.                           How do waterfree formulations
                                             On the contrary, diluted ingredients      correspond to diluted formulations
                                             are not conducive to waterfree for-       in terms of performance?
                                             mulations since they influence emul-
                                             sification properties, stability and      In order to compare our solid sham-
                                             abrasion. A high amount of emol-          poo and conditioner bars with tradi-
                                             lients compromises the foaming be-        tional systems like liquid shampoos
To obtain an optimal dispersion, the right   havior as it generates an emulsions,      and conditioners, we made test trials
ratio between wax and surfactants is         which inhibits foam formation.            on the conditions of combing wet
necessary.
                                                                                       and dry hair of diluted shampoo and
                                             Are there any special conditions          conditioner bars. Wet and dry comb-
                                             that need to be considered regard-        ing can be reduced via cationic ingre-
                                             ing waterfree formulations?               dients like Dehyquart Guar. The de-
What are the main challenges with                                                      gree of cationization influences the
waterfree formulations?                      The ratio between the waxy part and       hair smoothness and the electrostatic
                                             the surfactant part is important. The     repulsion.
Choosing the right ingredients is es-        amount of the wax should always be        For the consumer, this becomes ob-
sential to waterfree formulations.           higher than the amount of surfactant      vious in reduced combing.
When we produced the different               in order to obtain an optimal disper-     The dilution of the bars was impor-
solutions for our collection, for ex-        sion of the product.                      tant to gain the same active ingredi-
ample the easy foaming shampoo or            For an optimal performance, the spe-      ent content – the amount of cleansing
the solid conditioner, we used ingre-        cific kind of surfactant as well as its   substances in the surfactant – as tra-
dients that have the same properties         ratio in the formulation are important    ditional applications. The tested
as those used in conventional, di-           for generating a high amount of           products showed the same or an even
luted formulations. We chose sur-            foam, thereby providing a good            better performance than traditional
factants that quickly dissolve in wa-        cleansing effect.                         systems.                           Q

                                                                                                                               www.cossma.com   l 17
GO FUTURE: NEW IDEAS

Product development | This month Mintel is highlighting body care
products. Latest research concludes that brands with a clean, green narrative
and the safe and effective reputation of dermocosmetics can reach more
consumers.

              O
                        ver the next five years            the transformation of white to brown
                        A-Beauty will take off in the      adipocytes, while offering thwarting        Herbivore
                        West, charged by the popu-         recurrence by slowing the entry of          The oil retails in
               larity of holistically healthy lifestyles   glucose into fat cells. The concentrate     a 30 ml bottles.
               and natural, sustainable products.          also contains hyaluronic acid with a
               Ayurveda bodycare will be embraced          smoothing, moisturising effect, and
               by Europeans and Americans who              features a floral scent of iris, rose and
               want clean beauty solutions that im-        jasmine to charm the senses. It has a
               prove mind and body.                        pink gel texture with an immediate
                                                           cold effect that actively contributes
               Say “no” to dimples                         to the slimming efficiency.
               The range of Laboratoires Lierac
               Body-Slim includes “Concentré Cry-          Moisture for sensitive skin
               oactif Cellulite Incrustée” (Embed-         The brand d Program offers products
               ded Cellulite Cryoactive Concentrate)       for sensitive skin that are non-irritat-
               that has been designed to tackle en-        ing. With strictly selected ingredients
               crusted cellulite, and visibly soften       the formulations do not use alcohol,
               the curves, while diminishing bulges        fragrances nor paraben. The “Balance
               and smoothing dimples. Its active           Care” range aims to prevent water
               caffeine complex is said to stimulate       and oil imbalance. Available as part
               destocking, while WTB System trans-         of this is “Emulsion II”, described         vitality. The products are said to fea-
               forms white storage fat cells into fat      as a lightweight, silky-smooth for-         ture intoxicating scents and luxuri-
               brown adipocytes. It is also devel-         mula that continuously moisturises          ous textures to provide a little indul-
               oped with the active ingredient an-         and nourishes skin, repairs skin’s mi-      gence for enjoyable rituals. They are
               ti-relapse Pro-Irisine, to stimulate the    cro-damage and strengthens its tex-         free from animal cruelty, synthetic in-
               naturally produced irisin, boosting         ture. The easy-to-spread, non-acne-         gredients, and are retailed in recycla-
                                                           genic formula with low irritation is        ble and reusable packaging. Availa-
                                                           also said to prevent and improve dis-       ble as part of the brand is “Emerald
                                                           comfort such as stinging, itchiness         Cannabis Sativa (Hemp) Deep Mois-
                                                           and redness, while also defending           ture Glow Oil”, featuring ingredients
Laboratoires Lierac              d Program                 skin from reccurring roughness.             such ascannabis sativa seed (hemp)
Caffeine complex with            Emulsion II is free of                                                oil, shiitake mushroom and ashwa-
cryolipolysis mechanisms.        alcohol, fragrances       Pure natural power                          gandha root help to calm skin and
                                 and preservatives.
                                                           Herbivore is said to provide safe, non-     soothe irritations. According to the
                                                           toxic and effective products that use       manufacturer, it provides skin with
                                                           the power of nature to deliver tangi-       rich moisture and glow, all in a light-
                                                           ble results. The highly concentrated        weight and quick-absorbing formula.
                                                           formulas feature ethically-sourced,         It is free from THC and CBD.        Q
                                                           and certified organic active ingre-
                                                           dients, plant-based food-grade cold
                                                           pressed oils, steam distilled thera-
                                                           peutic grade essential oils, vitamins,                      AUTHOR:
                                                                                                                                                         photos: Mintel

                                                           minerals, GMO-free soy wax and nat-                         Michelle Strutton, Global
                                                                                                                       Research Manager Beauty & Per-
                                                           ural preservative Leucidal from rad-                        sonal Care, Mintel, London, UK,
                                                           ish root ferment to restore skin to its                     www.mintel.com

18 l COSSMA 4 I 2020
RUBRIKTITEL

www.cossma.com   l 19
20 l COSSMA 4 I 2020
   www.cossma.com
                               Africa Studio/Shutterstock.com
                       photos:Aquarius
                       photo:           Studio/Shutterstock.com
INGREDIENTS
Natural skin brightening ����������������������������������������������������������������������������������������������������������� p 22
Unlocking more potential����������������������������������������������������������������������������������������������������������� p 26
Formulations: Masks ���������������������������������������������������������������������������������������������������������������� p 28

                                                                                                                          www.cossma.com     l 21
Research | Many
                                                                                                              consumers ask for skin
                                                                                                              lightening products for
                                                                                                              their anti-ageing skin care.
                                                                                                              Scientists are continuing
                                                                                                              to work on new active
                                                                                                              ingredients. Here is an
                                                                                                              overview of the current
                                                                                                              status

              Natural Skin Brightening
                                                                  kle-free skin. With chronological age-    skin. For example, the efficacy of
                                                                  ing, dark spots, skin pigmentation,       such ingredients can be significantly
                                                                  freckles, and other visually percepti-    reduced, or even lost, if they pene-
                                                                  ble skin disorders, they often require    trate too deeply or not at all into skin
                                                                  treatment with skin lightening prod-      or fail to reach their biological site of
                                                                  ucts. Modern science has focused on       action in optimal quantities. Sun-
                                                      AUTHOR:
                          Shyam Gupta, PhD, Bioderm Research,     this omnipresent consumer desire to       screens, for example, must not pen-
                       Scottsdale, Arizona, USA, www.biodermre-   open new opportunities for market-        etrate too deeply into the skin. Oth-
                                                    search.com
                                                                  ers and formulators worldwide.            erwise, their efficacy would be
                                                                  New ingredients or improving visual       compromised and skin irritation
                                                                  appearance of skin are constantly de-     would increase. Skin whitening and

             M
                       other Nature blessed man-                  veloped. This article focuses on new      brightening agents, however, must
                       kind with a skin that pro-                 skin brightening ingredients, discov-     penetrate skin to reach tyrosinase-ac-
                                                                                                                                                        photo: aslysun/Shutterstock.com

                       vides a multitude of func-                 ered in the past five years.              tive cellular layers.
              tions: from protection from                         For these ingredients to deliver their    Any antioxidant or anti-inflammatory
              environemntal adversities to the ex-                function optimally, innovative topical    agent can also function as a skin
              pression of beauty. For the expression              delivery systems are required to trans-   brightening agent. The efficacy of
              of beauty, consumers desire young-                  port such ingredients to reach their      such ingredients can be maximized
              er-looking, vibrant, supple and wrin-               targeted biological site of action in     by formulating via appropriate deliv-

22 l COSSMA 4 I 2020
INGREDIENTS

ery systems. This requires a consid-          some discolouration under their nor-           chemical species. For example, hy-
eration of both the physical and              mal storage conditions.                        droquinone and arbutin can function
chemical properties of such ingredi-          Additionally, the presence of oxidiz-          via both mechanisms: they can block
ents.                                         ing metals such as Fe, Cu, and Ni,             tyrosinase antagonistically or reduce
                                              even in trace amounts, can lead to             melanin colour (eliminating double
Reaching the right skin layer                 discolorations from reddish brown to           bond conjugation in melanin’s chem-
For example, popular skin brighten-           bluish green tints in topical formula-         ical structure). In this regard arbutin,
ing agents, hydroquinone, kojic acid,         tions. Usually, the greater their antiox-      a glycoside of hydroquinone, is first
and arbutin, are fairly water soluble         idant or skin brightening efficacy the         converted into hydroquinone in vivo,
(5.0 – 6.0 g/100 mL). The use of such         faster this discolouration. This leads         which then carries out its dual func-
ingredients in formulations for rinse-        to ever-present formulation chal-              tion as hydroquinone.
off products, such as a suntan, sun-          lenges with such ingredients. Hy-              Ideally, a truly elegant new skin
screen, bar soap, or body wash, can           droxyphenyl ingredients, including             brightening ingredient should func-
lead to significantly reduced skin            flavones, isoflavones, and flavonoids,         tion by the above two mechanisms
brightening benefits. In the case of          are better formulated in an acidic pH          without imparting any undesirable
sunscreens formulations, which must           range (preferably 5.5 to 6.5), as their        after effects, such as skin irritation
not penetrate deep into skin, skin            degradation is faster under pH con-            caused by hydroquinone, which has
brightening ingredients may not               ditions higher than 8.0. The inclusion         caused regulatory concerns in several
reach tyrosinase active centres in ef-        of appropriate metal chelating agents          international markets.2 In general,
ficacious concentrations.                     is also recommended. A carefully               the incorporation of more than one skin
In case of bar soap or body wash              planned protocol for formulation sta-          brightening ingredient in a formulation
products such brightening agents              bility, efficacy, and safety gives best        is more beneficial in producing the
may simply get washed off when                results for developing an efficacious          desired skin lightening effect than a
rinsing the body after body wash ap-          consumer acceptable product adapt-             single ingredient on an equal weight
plication, resulting in an insufficient       able for international markets.                basis, especially if such ingredients
deposit on skin. Formulations de-                                                            provide their biochemical function
signed for leave-on or night-time use         New skin brightening                           via different pathways.
of such ingredients can provide               ingredients
greater efficacy.                             Researchers, formulators, and mar-             Brightened horizon for
                                              keters are always focused on “what             anti-ageing skin care
Problem of stability and                      is new and exciting”. An unquench-             A non-comprehensive listing of re-
discolouration                                able search for skin brightening in-           cently discovered skin brightening
Formulation stability is another con-         gredients and technologies has en-             agents is provided in Table 1.3 A
cern. A large number of skin bright-          sued since Elizabethan era.1 In                number of these ingredients may not
ening ingredients contain a hydroxy-,         practical terms, this effort has been          be commercially available at this
dihydroxy-, or polyhydroxyphenyl              successful via the pursuit of two basic        time, which signals an opportunity
chemical backbone. Such chemical              biochemical mechanisms: oxidase and            for ingredient manufacturers, formu-
compositions – besides being yellow           monooxygenase functions. This can              lators, and marketers worldwide.
to orange in colour – are also good           either prevent melanin formation by            In several articles both natural and
antioxidants. They naturally tend to          blocking tyrosinase (tyrosinase inhib-         synthetic skin whitening agents have
discolor in the presence of air and/          itors) or reduce existing melanin pig-         been reviewed.4
or light. This is not unexpected, as          ment (or melanin precursor biochem-            A natural product, bis(4-hydroxyben-
most antioxidants do tend to produce          ical intermediates) to a decolourised          zyl)sulfide, extracted from a Chinese

NN SKIN BRIGHTENING AGENTS

Dihydroxyphenylethyl glycine        n-Butylresorcinol                       trans-Cafferoyl stearate              bis-ethylhexanoate
Hydroxycinnamic acid                Asiaticoside                            Norartocarpetin                       Azaresveratrol
Phenylethyl resorcinol              Metformin                               Eupafolin                             Hydroxychalcone
Panduratin, Isopanduratin           Afzelin                                 Catechin                              Ovatodiolide
Galangin                            Glabridin                               Rengyolone                            Gnetin C
Asterina pectinifera                Polyarginine                            Citrus press-cakes                    Raspberry Ketone
Gastrodia elata                     6-O-Cafferoylarbutin                    Gingerol                              Ramalin
Hoelen extract                      Acanthoic acid                          Octaphlorethol                        Glyceollin
p-Hydroxybenzyl alcohol             Guggulsterone                           Cyclohexanediol

                                                                                                                                 www.cossma.com   l 23
INGREDIENTS

                                                                                                           It is remarkable that none of the na-
                                                                                                           ture-based skin brightening ingredi-
                                                                                                           ents have matched the efficacy of
                                                                                                           hydroquinone in a formulated cos-
                                                                                                           metics product. This may be due to
                                                                                                           its unique ability to perform both
                                                                                                           reduction and oxidation steps effi-
                                                                                                           ciently via hydroquinone/quinole/
                                                                                                           quinone redox pathway.14
                                                                                                           Many new and exciting whitening
                                                                                                           actives have been developed in the
                                                                                                           past five years; their discovery often
                                                                                                           aided by computational modelling
                                                                                                           techniques. These new actives, cou-
                                                                                                           pled with tailor-made delivery sys-
              In the laboratory, the effects of tyrosinase inhibitors are still being researched           tems, can help marketers, formulat-
                                                                                                           ers and ingredients suppliers
                                                                                                           worldwide find innovative solutions
                                                                                                           for enhancing the customer’s topical
              herbal source, Glastrodia elata, has               Since this is a sulfhydryl peptide the    beauty.                             Q
              shown exceptional tyrosinase inhibi-               odour contribution to formulations is
                                                                                                           References
              tion properties superior to kojic                  unknown as it is not yet commer-          1. Blay, The Journal of Pan African Studies, vol. 4, (2011). ht-
                                                                                                               tp://www.academia.edu/602086/Skin_Bleaching_and_
              acid.5 In practical formulations the               cially available.                             Global_White_Supremacy_By_Way_of_Introduction.
              development of off-odours due to its                                                         2. S. Gupta, Beauty Brightened: New Skin Brightening Ingre-
                                                                                                               dients, GCI, 30 – 32 (2014).
              sulfide bond may have to be ad-                    Identification with modern tools          3. Zolghadri et al., A comprehensive review on tyrosinase in-
                                                                                                               hibitors, J Enzyme Inhib Med Chem. 2019 Dec;34(1):279-
              dressed, since this molecule is easy               Computational modelling has be-               309. DOI: 10.1080/14756366.2018.1545767;
                                                                                                               Pillaiyar et al., Skin whitening agents: medicinal che-
              to manufacture commercially by sim-                come a successful tool in the identi-         mistry perspective of tyrosinase inhibitors, J Enzy-
                                                                                                               me Inhib Med Chem. 2017 Dec; 32(1):403-425. DOI:
              ple synthesis.                                     fication of potential new tyrosinase          10.1080/14756366.2016.1256882; Lee et al., Natu-
                                                                                                               ral, Semisynthetic and Synthetic Tyrosinase Inhibitors,
              It is worthy to note that most prior               inhibitors. DMY has been reported to          J Enzyme Inhib Med Chem, 31 (1), 1-13, 2016;DOI:
                                                                                                               10.3109/14756366.2015.1004058; Kanlayavattanakul,
              studies of tyrosinase inhibition have              inhibit tyrosinase. Molecular model-          Plants and Natural Products for the Treatment of Skin Hy-
                                                                                                               perpigmentation – A Review, Planta Med 2018; 84(14):
              been carried out with mushroom ty-                 ling found that this ingredient inter-        988-1006; DOI: 10.1055/a-0583-0410.
              rosinase. In a recent study the use of             acted with amino acid residues            4. Chen et al., Discovery of highly potent tyrosinase inhi-
                                                                                                               bitor, T1, with significant anti-melanogenesis ability by
              recombinant human tyrosinase for                   Tyr78, His85, and Ala323, occupying           zebrafish in vivo assay and computational molecular
                                                                                                               modeling, Sci Rep. 2015 Jan 23; 5:7995. DOI: 10.1038/
              screening purposes has been more                   the active site leading to the inhibi-        srep07995.
                                                                                                           5. Mann et al., Inhibition of Human Tyrosinase Requires Mo-
              predictive. The introduction of a new              tion of tyrosinase. This study may            lecular Motifs Distinctively Different From Mushroom Ty-
                                                                                                               rosinase, J Invest Dermatol, 138 (7), 1601-1608 Jul 2018;
              skin brightening agent, isobuty-                   provide a new method for screening            DOI: 10.1016/j.jid.2018.01.019.
              lamido thiazolyl resorcinol (Thiami-               tyrosinase inhibitors.9 In another        6. Dilokthornsakul et al., The Clinical Effect of Glutathione
                                                                                                               on Skin Color and Other Re-lated Skin Conditions: A Sys-
              dol) resulted from this research.6                 study, computational modelling                tematic Review, J Cosmet Dermatol, 18 (3), 728-737 Jun
                                                                                                               2019; DOI: 10.1111/jocd.12910; Sonthalia et al., Glutathi-
              Although it is a synthetic ingredient,             showed validamycin to be a potent             one for skin lightening: a regnant myth or evidence-based
                                                                                                               verity?, Dermatol Pract Concept. 2018 Jan 31; 8(1):15-
              it offers an insight into the biochemi-            tyrosinase inhibitor by binding at            21. DOI: 10.5826/dpc.0801a04. eCollection 2018 Jan.
                                                                                                           7. Shen et al., Novel Tyrosinase Inhibitory Peptide Wi-
              cal mechanisms by which skin bright-               HIS85, HIS244, GLU256, HIS259, and            th Free Radical Scavenging Abili-ty, J Enzyme In-
                                                                                                               hib Med Chem, 34 (1), 1633-1640 Dec 2019; DOI:
              ening can be achieved for future                   ASN260 of the tyrosinase active-site.10       10.1080/14756366.2019.1661401.
              research.                                          Similar computational modelling has       8. Fan et al., An Inhibition Mechanism of Dihydromyrice-
                                                                                                               tin on Tyrosinase and the Joint Effects of Vitamins B 6,
              Glutathione has long been proposed                 been successful in evaluating tyrosi-         D 3 or E,Food Funct, 8 (7), 2601-2610 2017 Jul 19; DOI:
                                                                                                               10.1039/c7fo00236j.
              as a skin whitening natural tripeptide             nase inhibition by several Chinese        9. Wang et al., The effect of validamycin A on tyrosinase:
                                                                                                               Inhibition kinetics and computational simulation, Int J
              ingredient. However, controversy has               medicinal plant extracts.11                   Biol Macromol, 55, 15-23 Apr 2013; DOI: 10.1016/j.ijbio-
                                                                                                               mac.2012.12.040.
              shrouded its real efficacy.7 Despite of            A recombinant enzyme complex has          10. Gao et al., Predicting Tyrosinase Inhibition by 3D QSAR
              this, it should be noted that even a               been proposed as the next generation            Pharmacophore Models and Designing Potential Tyro-
                                                                                                                 sinase Inhibitors From Traditional Chinese Medicine Da-
              0.2% use of this ingredient in a top-              skin whitening agent. However, its              tabase, Phytomedicine, 38, 145-157 2018 Jan 1; DOI:
                                                                                                                 10.1016/j.phymed.2017.11.012.
              ical skin care product can lead to                 commercial viability is yet un-           11. Shin et al., Effective Melanin Degradation by a Syn-
                                                                                                                ergistic Laccase-Peroxidase Enzyme Complex for Skin
              sulphur odours which are unaccept-                 known.12 Moreover, its practical for-          Whitening and Other Practical Applications, Int J Biol
                                                                                                                Macromol, 129, 181-186 2019 May 15; DOI: 10.1016/j.
                                                                                                                                                                               Photo: Nawanit/Shutterstock.com

              able to the customer (practical expe-              mulation may pose skin delivery                ijbiomac.2019.02.027.
              rience of this author).                            challenges.13 As mentioned earlier, a     12. Shin et al., Development and evaluation of topical for-
                                                                                                                 mulations for a novel skin whitening agent (AP736)
              Dihydromyricetin (DMY), a new pep-                 proper delivery system is required for          using Hansen solubility parameters and PEG-PCL poly-
                                                                                                                 mers, Int J Pharm, 552 (1-2), 251-257 2018 Dec 1; DOI:
              tide that is structurally related to glu-          most topical skin brightening agents            10.1016/j.ijpharm.2018.09.064; S. Gupta, Topical deli-
                                                                                                                 very of skin care ingredients, Cosmetics & Toiletries, Vol
              tathione, has shown tyrosinase inhi-               to assure both their physically stabil-         129, No. 8, 26 – 39 (2014).
                                                                                                           13. Chen et al., Unveiling characteristics of dye-bearing
              bition via a mechanism unrelated to                ity and their targeted delivery into            microbial fuel cells for energy and materials recycling:
                                                                                                                 Redox mediators, Int J Hyd Energy, Volume 38, Issue 35,
              that of glutathione.8                              the skin.13                                     22 November 2013, Pages 15598-15605.

24 l COSSMA 4 I 2020                                                                                                                                www.cossma.com
CAN YOU
KEEP
A SECRET?
Find out more and visit us at in-cosmetics global,
31 March – 2 April 2020, Barcelona, Booth N20

Contact us for more information:
care@zschimmer-schwarz.com
Unlocking more potential
Formulation | Although currently in great demand in cosmetics,
Cannabidiol is quite chemically unstable. A study about effectiveness
while embedded in capsules seems promising. Here are the results.

                                                                  Activys capsules have been selected       cytes treated with arachnoids acid
                                                                  among the delivery system platforms       (20 microM) and figure 1C refers to
                                                                  available for encapsulating the active    sebocytes treated with arachnoids
                                                                  ingredient and granting its dispersion    acid (20 microM) and CBD oil bal-
                                                                  in water-based formulae as well as        ance at 0.02%. Lipids are stained by
                                                                  protecting it from premature oxida-       oil red. When sebocytes are treated,
                                                    AUTHORS:
                   Dr Natascia Grimaldi, Area Sales Manager,      tion.                                     lipogenesis induced by arachnoids
                       Patricio Gabarrón, Efficacy and Safety     More in details, these are lipid-based    acid is dramatically inhibited.
                  Manager, Infinitec Activos, Barcelona, Spain,   capsules, made of polyunsaturated         A semi-quantitative analysis has
                                               www.infinitec.es
                                                                  fatty acids (PUFAs). Because of their     been also performed: The combina-
                                                                  composition, they are more flexible       tion of actives is able to reduce the
                                                                  than conventional capsules, resulting     induced lipogenesis by a 33%.

             D
                      ifferent actives are nowadays               in improved penetration. Further-
                      available for oily skin treat-              more, a unique feature is that it is an   Anti-inflammatory ability
                      ment, but most of them just                 active-per-se capsule; upon penetra-      As discussed above, activys capsule
              work either on sebum production, or                 tion, the capsule is metabolized and      has the unique feature to be ac-
              inflammation or have antibacterial or               CBD is released.                          tive-per-se. It shows anti-inflamma-
                                                                                                                                                       Photos: Kimberly Boyles/Shutterstock.com, author

              anti-mycotic activity. Cannabidiol                                                            tory activity, and enhances CBD ac-
              (CBD) can both regulate sebum pro-                  Sebum control                             tivity. In order to assess this, we have
              duction and exhibit anti-inflamma-                  The ability of CBD in combination         performed gene expression analysis,
              tory activity.                                      with capsules to inhibit excessive se-    targeting specific genes involved in
              Unfortunately, it is a highly lipophilic            bum production has been demon-            the inflammatory process.
              molecule and suffers of chemical in-                strated by oil-red assay. For this        The study has been performed using
              stability, undergoing oxidation. Be-                study, there was used arachnoids          human keratinocytes (HaCaT) as
              cause of this, it is important to use               acid as lipogenesis enhancer. Figure      skin cell model and human follicle
              appropriate vehicles for unlocking                  1A refers to not treated sebocytes        dermal papilla cells (HFDPC) as scalp
              CBD potential.                                      (control), figure 1B refers to sebo-      cell model. The capsules have dis-

26 l COSSMA 4 I 2020
INGREDIENTS

fig 1: Oil-red assay (A) non-treated sebocytes; (B) sebocytes treated with 20 microM arachnoid acid; (C) sebocytes treated with 20 microM
arachnoid acid and 0.02% of CBD oil balance.

played significant anti-inflammatory
effects both on HaCaT and on HF-                    Product                Critical                       Microorganisms
DPC, by reducing the inflammation                                      ­Concentration
of a 40% average.                                                                          S. Aureus        M. Restricta     M. Globosa

                                                    CBD Oil Balance         MIC             0.005%             0.2%              0.2%
Microflora balancing                                                        MBC
INGREDIENTS

                                                                                         MORE INFORMATION
                                                                                         ONLINE
                                                                               You can access the details of each
                                                                               formulation at www.cossma.com
                                                                               webcode 100362.

             Masks
             Formulations | They are more than just a treatment. A lot of consumers love
             maks  for the concentrated active ingredients they feel on their skin while they
             enjoy a little break – at home or in the cosmetic studio. We present a selection
             of formulations and ingredients suppliers that provide a comprehensive look
             at the latest innovations in the market.

              Mild Jelly Shower Gel          Dry Peel Off Mask – Superwoman   Hydrating and purifying clay Mask
              Azelis                         Eckart                           Roelmi HPC

              Happy Natural Day Shower Gel   Repair Hair Mask                 Bamboo Glow – Purifying Black Peel-off
              BASF                           GfN Selco                        Mask

              Peel Off Mask Gold             Color Changing Clay Mask         Safic Alcan
              BASF                           Kobo
                                                                                                                                            photo: Prostock Studio/Shutterstock.com

                                                                              Conditioning Mask with vegetable oils.
              Unisex Tissue Mask             Matte Lite TF6                   Seppic
              Biesterfeld                    MMP

              Snow Glitter Peel Off Mask     Mango Hair Mask
                                                                              In the Mai issue, we will be focusing on formulations for
              CLRC Spezialchemie             NRC                              natural and organic cosmetics. In June, formulations for
                                                                              sun care for all skins and all over the body will take cen-
                                                                              tre stage. All of the information published here has been
              Scoobable Hair Soufflé         Fresh scalp revival mask         carefully assembled. Neither the publishers nor the de-
              Croda                          Provital                         velopers of these formulations can accept responsibility
                                                                              for their safety or accuracy.

28 l COSSMA 4 I 2020                                                                                               www.cossma.com
ADVERTISEMENT                                                                                                              INGREDIENT HIGHLIGHT

In the BELSIL® eco manufacturing
process, the use of fossil-based raw
materials is compensated 100% by
biomethanol from renewable resources.

                                         photo: Wacker Chemie AG

BELSIL® ECO
Beauty meets Sustainability

T
       he push for sustainability                                  Instead of standard methanol, for in-        Highly Diversified: the Product
       is about more than just                                     stance, the biomethanol used in this         Range
       good intentions these days                                  product has been obtained exclusively
– it’s part of our company’s strat-                                from renewable raw materials such as         Sustainably manufactured BELSIL®
egy and a component of our over-                                   straw, grasses, sugar beets or other         eco is available as a silicone for use
all corporate responsibility. In light                             plant residues. TÜV continuously             in make-up, skin care, hair care and
of ambitious climate goals, dwin-                                  monitors this manufacturing process          hairstyling products. Find the
dling fossil-based resources and                                   and the use of biobased raw materials.       right BELSIL® eco product below:
a growing global population, man-                                                                               BELSIL® eco: DM 0.65, DM 5, DM 10,
ufacturing processes that minimize                                 Easy to Use – Identical Results              DM 20, DM 50, DM 100, DM 350,
environmental impact are increas-                                                                               DM 1000, DM 60.000, GB 1020 and
ingly becoming a deciding factor                                   You can use BELSIL® eco without              TMS 803.
on the market. BELSIL® eco is                                      making any changes to your formula-
a powerful response to these devel-                                tion or production process. As a true        Visit us at in-cosmetics Global 2020,
opments.                                                           drop-in solution, BELSIL® eco can            Barcelona, booth S 60!
                                                                   simply be used in place of classic BEL-
Inspected and certified                                            SIL® – neither the product formulation
                                                                   nor its performance has changed.
The creation of BELSIL® eco was                                    Even though it is made with renewa-
motivated by a powerful drive for                                  bles, BELSIL® eco is chemically iden-
raw materials that preserve our nat-                               tical to its classic counterpart, offering    Wacker Chemie AG
ural resources. To that end, BELSIL®                               you an efficient, verifiable option for       Hanns-Seidel-Platz 4

eco has been certified by Germany’s                                more environmentally friendly pro-            81737 Munich, Germany

TÜV technical inspectorate accord-                                 duction and for achieving your inter-         Email: info@wacker.com

ing to exacting standards.                                         nal sustainability objectives.                www.wacker.com/belsileco

                                                                                                                                                www.cossma.com   l 29
INGREDIENTS

News                                             New
                                                  OF T H E
                                                          s
Happy Birthday                                   Month
BEAUTY FORUM LEIPZIG
BEAUTY FORUM | This year BEAUTY
FORUM LEIPZIG celebrates its 10th anni-
versary. From April 25 to 26 attendees will
find a varied program and more than 400
exhibitors and brands from all sectors of
professional skin care. The diverse specialist
and supporting program includes scientific
congresses on the topics of podiatry and
anti-aging, practical workshops, informative
company presentations and treatments as
well as exciting championships and enter-
taining make-up and hair shows in the trade
fair calendar.
www.beauty-fairs.de/leipzig

                                                    INFLUENCE ON THE                                Natural Emulsifier
                                                    SKIN ­MICROBIOME                                GATTEFOSSÉ | The natural and
                                                                                                    PEG-free O/W emulsifier “Emulium
                                                                                                    Mellifera MB” bases on the trans-
                                                    CLR | Skin microbiota plays a largely
                                                    positive, but sometimes detrimental             formation and functionalization
                                                    role for skin. “CutiBiome CLR” was              of natural waxes; a patented
                                                    developed to anticipate on the ambiv-           technology developed by Gattefossé
                                                    alence of members of the skin micro-            oleochemists. From beeswax and
                                                    biota implied in the loss of skin health,       jojoba wax, the wax butter obtained
                                                    for instance Cutibacterium acnes. It is         by esterification and interesterifi-
                                                    said it is fully abolishing the film form-      cation brings a unique sensoriality
                                                    ing activity and significantly inhibiting       and moisturizing properties to this
                                                    the growth of C. acnes I-A1. Sebum,             emulsifier, so the company. Flexible,
                                                    comedones, pustules and pimples are             promises to allow the creation of a
                                                    reduced dramatically.                           wide range of textures.
                                                    www.clr-berlin.com                              www.gattefosse.com
                                                                                                                                            photos: BEAUTY FORUM, CLR, Lipoid Cosmetic

                                                    NEW EXTRACT
                                                    LIPOID KOSMETIK | “Blossom Honey Pro” is an extract based on organic acacia
                                                    honey that is refined for cosmetic use. Its composition with more than 200 bioactive
                                                    compounds promises to nourish and supply energy to enhance skin cell proliferation
                                                    and activity. It should moisturize powerfully through increased water attraction and
                                                    storage. It enhances skin volume and plumps it by generating osmotic pressure, says
                                                    the company.
                                                    www.lipoid-kosmetik.com

30 l COSSMA 4 I 2020                                                                                                      www.cossma.com
INGREDIENTS

                                                                                                                                                             News
                                                                                  INNOVATION AWARD
                                                                                  INOLEX | The company received the Innovation Award for its “AminoSensyl Amino Lipid
                                                                                  Platform” during the Home and Personal Care Ingredients (HPCI) Exhibition and Conference
                                                                                  in Mumbai, India. The “HPCI Innovation Zone Best Ingredient Awards” recognize outstanding
                                                                                  innovations from the cosmetics amongst others. Launched in 2019, the portfolio includes
                                                                                  “AminoSensyl HC” for hair care, and “AminoSensyl SC” for skincare.
                                                                                  www.inolex.com

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                                      Information is liberating.
                                      Education is the premise of progress.
                                      Today’s consumers are looking for honest claims and
                                      traceable ingredients. Univar Solutions selection of
                                      ingredients featured in Clean by Design includes the
                                      best innovations to help create an enjoyable texture
                                      while having a low impact on the environment.
                                                                                                                                     Sustainable solutions for
                                      Come and experience our newest concept at                                                      proof toothpaste
                                      in-cosmetics Global 2020 on booth AH 70!

                                                                                                                                     OMYA | “Omyacare S 75-KP” and “Omya-
                                                                                                                                     care S 95-KP” minerals now are approved
                                                                                                                                     by Ecocert organization for natural raw
                                                                                                                                     materials. The certificate confirms that both
                                                                                                                                     ingredients are natural, environmentally
                                                                                                                                     friendly and sustainable. Omyacare particles
                                                                                                                                     sourced from natural calcium carbonate can
                                                                                                                                     be used as cleansing agents with different
                                                                                                                                     grades of abrasiveness that adjust the colour,
                                                                                                                                     viscosity and texture of toothpaste and rinse
                                                                                                                                     off applications, says the company.
                                                                                                                                     www.omya.com

                                                                                                          INSTANTLY ­ILLUMINATED SKIN
                                                                                                          GIVAUDAN | The company developed “Skin Care Highlighter”, a trans-
                                                                                                          forming gel dedicated for the cheekbones. This microbiomefriendly skin
photos: Inolex, Omya, Givaudan

                                                                                                          perfecter highly concentrated in active ingredients to instantly illuminates
                                                                                                          the skin for a natural look, says the company. The “Skin Care Highlighter”
                                                                                                          Infused by six active ingredients: upcycled vetiver roots, Vetivyne Flash-
                                                                                                          white Unispheres, Brightenyl, Yogurtene Balance, Unitamuron H-22,
                                                                                                          Cristalhyal.
                                                                                                          www.givaudan.com

                                                                                                                                                                  www.cossma.com   l 31
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