Toward the Next Growth Phase - Shigeo Taniuchi President and CEO Santen Pharmaceutical Co., Ltd.
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Toward the Next Growth Phase Shigeo Taniuchi President and CEO Santen Pharmaceutical Co., Ltd. J.P. Morgan Healthcare Conference January 11, 2021 Copyright© 2021 Santen All rights reserved. 1
Forward-Looking Statements Information given in this presentation contains certain forward-looking statements concerning forecasts, projections and plans whose realization is subject to risk and uncertainty from a variety of sources. Actual results may differ significantly from forecasts. Business performance and financial condition are subject to the effects of medical regulatory changes made by the governments of Japan and other nations concerning medical insurance, drug pricing and other systems, and to fluctuations in market variables such as interest rates and foreign exchange rates. The process of drug research and development from discovery to final approval and sales is long, complex and uncertain. Individual compounds are subject to a multitude of uncertainties, including the termination of clinical development at various stages and the non-approval of products after a regulatory filing has been submitted. Forecasts and projections concerning new products take into account assumptions concerning the development pipelines of other companies and any co-promotion agreements, existing or planned. The success or failure of such agreements could affect business performance and financial condition significantly. Business performance and financial conditions could be affected significantly by a substantial drop in sales of a major drug, either currently marketed or expected to be launched, due to termination of sales as a result of factors such as patent expiry and complications, product defects or unforeseen side effects. Santen also sells numerous products under sales and / or manufacturing license from other companies. Business performance could be affected significantly by changes in the terms and conditions of agreements and/or the non-renewal of agreements. Santen is reliant on specific companies for supplies of certain raw materials used in production. Business performance could be affected significantly by the suspension or termination of supplies of such raw materials if such an event were to adversely affect supply capabilities for related final products. Copyright© 2021 Santen All rights reserved. 2
CORE PRINCIPLE and WORLD VISION CORE PRINCIPLE “Exploring the secrets and mechanisms of nature in order to contribute to people’s health” * WORLD Happiness with Vision VISION The Happiest Life for every individual, through the Best Vision Experience * Santen’s original interpretation of a passage from the Zhongyong (The Doctrine of the Mean) by Confucius. Copyright© 2021 Santen All rights reserved. 4
Strategy Framework: Toward 2030 Aim to resolve social issues through expansion of solutions in ophthalmology Ophthalmology Wellness Inclusion Copyright© 2021 Santen All rights reserved. 5
Challenge of Diversification in Ophthalmology Expanding business scope for further growth as a specialized company Geography coverage Technology Americas EMEA New modality Asia Small molecules China Device Japan Digital Inclusion Diagnosis Treatment (reimbursement) Treatment (out of pocket) Wellness Value Offerings Copyright© 2021 Santen All rights reserved. 6
Challenge of Diversification in Ophthalmology Expanding business scope for further growth as a specialized company Geography coverage Technology Americas EMEA New modality Asia Small molecules China Device Japan Digital Business Inclusion Diagnosis domain Treatment (reimbursement) Treatment (out of pocket) Wellness Value Offerings Copyright© 2021 Santen All rights reserved. 7
Expanding Solutions in Ophthalmology Enter new modality, device and digital domains while also enhancing core expertise Digital Device Small Molecules New Modality Check-up Diagnosis Follow-up Device Enhancement Expansion of Treatment (Reimbursement) commercialization of core business pharmaceutical business Treatment (Out of Pocket) Wellness Copyright© 2021 Santen All rights reserved. 8
Expanding Solutions in Ophthalmology Expansion of portfolio through active partnerships Digital Device Small Molecules New Modality Check-up Support Glaucoma ophthalmologists’ Diagnosis Digital training treatment support Follow-up device Gene therapy Device Enhancement Expansion of Treatment (Reimbursement) commercialization of core business pharmaceutical Glaucoma device ROCK business inhibitor Cell therapy IOL Treatment Approach to Myopia progression (Out of Pocket) myopia Ptosis reduction for children Wellness Copyright© 2021 Santen All rights reserved. 9
Santen’s Global Presence Robust revenue driven by business expansions outside Japan Overseas CAGR*1:17% Japan China China Exceed market growth Double-digit growth 9% Asia Market share of approx. Market share No.1*2 7% FY2019 Consolidated 50% *2 Revenue EMEA 15% 241.6 Americas Japan Billion yen Asia EMEA 0% 68% Double-digit growth Exceed market growth Market share No.2*2 Securing top 5 position*2,3 Japan *1: FY2010-2019 CAGR *2: Copyright © 2020 IQVIA. JPM 2019.10–2020.9 and CAGR*1:7% IQVIA MIDAS 2019; Santen analysis based on IQVIA data. Reprinted with permission *3: Excluding anti-VEGF Copyright© 2021 Santen All rights reserved. 10
Unleashing Our Strengths Contributing to the development of ophthalmology by combining our specialized knowledge with external expertise and technology Partnership/ Product Product development supply Global Communication with platform ophthalmology stakeholders Copyright© 2021 Santen All rights reserved. 11
Our Plan to Enter the United States Eyevance acquisition and DE-128 aimed at developing a future revenue pillar Pipeline in the US As of October 2020 Acquisition of commercial platform DE-128 (Application filed) Glaucoma DE-117 (P3) 45+ 5+ DE-126 (P2b) Field forces Unique FOTE products Vernal Verkazia keratoconjunctivitis (Application filed) Exclusive US sales partner Uveitis DE-109 (P3) for MicroShunt Copyright© 2021 Santen All rights reserved. 12
Our Vision for Future Growth Aim to increase corporate value by further strengthening existing geographies, entering the US market, and new business New business US Existing business in Japan, China, Asia, EMEA 2030 Copyright© 2021 Santen All rights reserved. 13
Our Diversity and Inclusion Promoting D&I to enhance corporate value over the mid-to-long term Diversification of talented “Blind Experience” human resources The global movement putting disability on the business leadership agenda. Copyright© 2021 Santen All rights reserved. 14
Happiness with Vision Copyright© 2021 Santen All rights reserved. 15
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