THE PHARMACEUTICAL INDUSTRY'S ROLE IN THE GLOBAL ENVIRONMENTAL SUSTAINABILITY MOVEMENT - Aptar
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Noble THE PHARMACEUTICAL INDUSTRY’S ROLE IN THE GLOBAL ENVIRONMENTAL SUSTAINABILITY MOVEMENT In this article, Alex Catino, Product Commercialisation Associate at Noble, discusses current trends in the pharmaceutical industry in relation to environmental sustainability in healthcare. Environmental sustainability is a broad, first Conference on the Human Environment, expansive concept that can apply which is widely considered one of the earliest to everything from agriculture and global meetings to discuss the environment, manufacturing to building design. But how conservation and sustainability.2 In is it defined? the early 1990s, “green brands” began The United States Environmental to emerge, with companies using their Protection Agency (EPA) defines environmental and sustainable business sustainability based on an overarching practices as selling points for consumers. principle: “Everything that we need for By 2012, sustainability had cemented itself our survival and well-being depends, in the collective conscience of consumers either directly or indirectly, on our natural and companies alike, with corporate social environment. To pursue sustainability is to responsibility (CSR) and triple bottom line create and maintain the conditions under reports that measure financial, social and which humans and nature can exist in environmental performance emerging as productive harmony to support present and standard responses to that consciousness.3 future generations.”1 The creation of the EPA in 1970 is one ENVIRONMENTAL SUSTAINABILITY of many inflection points that sparked the IN HEALTHCARE modern global environmental movement. In 1972, the United Nations (UN) held the The WHO defines an environmentally sustainable health system as one that “improves, maintains or restores health, Alex Catino while minimising negative impacts on the Product Commercialisation Associate “Within the healthcare environment and leveraging opportunities T: +1 888 933 5646 ext 170 sector, environmental to restore and improve it, to the benefit E: acatino@gonoble.com of the health and well-being of current sustainability involves and future generations.”4 Most importantly, Noble using resources as human health is inextricably linked to the 121 South Orange Avenue efficiently as possible, health of the environment, according to the Suite 1070 Australian Medical Association.5 Orlando without compromising the FL 32801 Within the healthcare sector, United States quality of patient care.” environmental sustainability involves using resources as efficiently as possible, without www.gonoble.com 44 www.ondrugdelivery.com Copyright © 2020 Frederick Furness Publishing Ltd
Noble A member company of the World Business Council for Sustainable Development, “A major sustainability issue confronting the healthcare sector Aptar also recently joined the UN Global today is the number of hospitals that are ageing, meaning Compact – the world’s largest citizenship their technologies and systems are becoming outdated.” initiative, which focuses on universal principles in the areas of human rights, labour, the environment and anti- compromising the quality of patient care. and sustainability in mind. In a 2018 corruption. “We are extremely proud of Strategies that can foster environmental Pharma Manufacturing article on achieving [our] commitment to reducing [Aptar’s] sustainability within this sector are sustainability in an evolving pharma impact on the planet while creating quality promoting efficient management of resources sector, Tom Egan, Vice-President, Industry products,” said Stephan Tanda, Aptar and increasing sustainable procurement. Services, PMMI, said: “Pharmaceutical President and CEO. A major sustainability issue confronting manufacturers must implement packaging Aptar Pharma, part of AptarGroup, the healthcare sector today is the number solutions that minimise the environmental is the company’s provider of innovative of hospitals that are ageing, meaning their impact of expanding product lines, build drug delivery solutions to pharmaceutical, technologies and systems are becoming sustainability practices into the development consumer healthcare and biotech customers outdated. Managing the renovation or of new delivery systems, seek utility savings worldwide. Its patented Freepod multi- replacement of these facilities in a sustainable in new automation strategies and leverage dose, preservative-free nasal spray device way – using elements like green building serialisation.” For example, the article with GlaxoSmithKline’s Otrivin won design and construction, and incorporation says, when it comes to accurate dosing, the World Packaging Organisation’s of on-site renewable energy technology – patients who achieve better results with oral, prestigious WorldStar Award in 2019 for its can have a direct impact on the environment injectable or nasal sprays versus other formats sustainability impact. The award annually without impacting patient care.4 provide a strong incentive for companies to recognises advancement and excellence in The healthcare sector is seeing increased offer those new delivery mechanisms. packaging design and technology. pressure to make commitments and tangible These advancements in drug delivery progress that positively impact both the add to the growing variety of products on environment and society. The global shift the market. In addition, a shift towards towards achieving a sustainable future smaller batch runs allows for more has made environmental stewardship an product diversity. However, more frequent expected norm. changeovers on machinery are required to deliver this diversity of products, which in CURRENT TRENDS IN THE turn can have negative impacts on energy PHARMACEUTICAL INDUSTRY consumption at the manufacturing level. An ageing world population and improved CSR FOR ENVIRONMENTALLY access to healthcare in emerging markets SUSTAINABLE DRUG DELIVERY are driving increased demand within the pharmaceutical industry. Manufacturers today Today, socially and environmentally are responding to the demand by producing responsible pharmaceutical companies are a wider variety of pharmaceutical products. developing ways to produce their products However, the resulting changes to production more efficiently and sustainably. Companies can conflict with sustainability objectives. have created self-imposed targets and A key challenge for the pharmaceutical initiatives to reduce the impact of their industry is how to accommodate demanding activities and products on the environment production schedules and increased product while keeping the patient and product variety while also keeping the environment efficacy top of mind (Figure 1). APTAR IS A GLOBAL LEADER IN SUSTAINABILITY A key challenge for the pharmaceutical industry One company making a difference in its is how to accommodate commitment to creating a more sustainable future is AptarGroup, a global leader in demanding production drug delivery, consumer product dispensing schedules and increased and active packaging solutions. Earlier this product variety while also year, Barron’s included Aptar on its list of Figure 1: A reusable, resettable the “100 Most Sustainable Companies in Noble training autoinjector, keeping the environment built to replicate the form and America” for the second consecutive year, function of the true drug delivery and sustainability in mind.” and Newsweek named it one of “America’s device upon which it is based. Most Responsible Companies 2020”. Copyright © 2020 Frederick Furness Publishing Ltd www.ondrugdelivery.com 45
Noble Figure 2: Various Noble patient training devices, all of which are resettable for ongoing use and practice. NOBLE’S COMMITMENT them overcome their anxiety and fears – shipping and more sharps waste. When a TO ENVIRONMENTAL rather than using their single-use actual patient uses a resettable training device, SUSTAINABILITY INITIATIVES drug delivery devices filled with medication they are more likely to receive a proper dose for practice, which requires disposal when using the actual drug delivery device. Noble, an Aptar Pharma company, after a single use. In addition, pharma Simply put, when a patient gets it right the promotes healthy patient outcomes for companies often achieve cost reductions first time, our footprint shrinks. people who self-administer their drug and support their own sustainability Noble is also an environmental therapies through the development of initiatives by using Noble’s resettable steward when it comes to its packaging robust training and onboarding solutions training devices. designs, balancing sustainability with for the world’s top pharma brands and There is an extraordinary, and often an understanding that the patient and biotech companies. The company shares overlooked, downstream cost to the product efficacy are key factors in the Aptar’s commitment to creating a more healthcare system when patients do not design process (Figure 3). This commitment sustainable future. comply with their self-administered drug to sustainable packaging extends to Noble’s A prime example of how Noble therapies – and noncompliance often travel kits (Figure 4), which are designed to contributes to a sustainable environment begins because of a lack of upfront and protect temperature-sensitive medications. is through resettable training devices ongoing training. All materials used within Noble’s (Figure 2). These reusable training devices Not only does the patient suffer when packaging are compliant with the allow patients to repeatedly practise the they do not receive the proper dose of their Restriction of Hazardous Substances use of autoinjectors, prefilled syringes and medication, it also hurts the healthcare (RoHS) directive that originated in nasal delivery devices to educate themselves system by creating the need for additional the European Union to restrict the use on proper usage technique and to help goods and packaging, such as additional of specific materials that are hazardous to the environment, including lead, mercury, cadmium, hexavalent chromium, polybrominated biphenyls (PBB), polybrominated diphenyl ethers (PBDE), and four different phthalates (DEHP, BBP, BBP, DIBP).6 Additionally, nearly all of the company’s packaging is also free of harmful chemicals such as paint and electroplated plastic components. CONCLUSION Due to pressing environmental needs, a Figure 3: A Noble patient focus on preserving the environment for training kit made with recyclable materials. future generations and a shift to more responsible consumption and production, 46 www.ondrugdelivery.com Copyright © 2020 Frederick Furness Publishing Ltd
Noble companies have embraced more sustainable order to increase patient adherence and strategies. The link between sustainability, confidence and decrease usage errors. both environmental and social, has clear ties Noble is an Aptar Pharma company. to human health, making advancement of these strategies a priority for healthcare and REFERENCES pharmaceutical industries alike (Figure 4). 1. “Learn About Sustainability”. Web ABOUT THE COMPANY Page, US Environmental Protection Agency, Accessed August 2020. Noble is focused on fostering healthy 2. “Report of the United Nations patient outcomes for those who self- Conference on the Human administer drug therapies through the Environment, Stockholm, 5-16 June development of robust training devices and 1972”. UN Digital Library, 1973. onboarding solutions for the world’s top 3. Silvis J, “Connecting Sustainability to pharma brands and biotech companies. the Healthcare Mission”, Healthcare Noble manufactures and commercialises Design Magazine, May 29, 2012. training devices that mimic the exact feel, 4. “Environmentally Sustainable Health Figure 4: A reusable Noble travel kit that is temperature controlled to force and function of drug delivery devices Systems: A strategic document”. keep medications at their optimal such as autoinjectors, prefilled syringes and WHO, February 7, 2017. temperature while away from home. on-body, nasal and pulmonary devices in 5. “Environmental Sustainability in Health Care – 2019”. Position Statement, Australian ABOUT THE AUTHOR Medical Association Web Page, Alex Catino, Product Commercialisation Associate at Noble, an Aptar Pharma company, March 20, 2019. is responsible for supporting development, launch and commercialisation of Noble’s 6. “RoHS Compliance FAQ”. platform products. Alex holds BSc degrees in business administration and psychology. RoHS Guide Web Page, Accessed August 2020. BOOK BY 30TH SEPTEMBER AND SAVE £400 BOOK BY 30TH OCTOBER AND SAVE £200 BOOK BY 30TH NOVEMBER AND SAVE £100 SMi Group Proudly Presents the 13th Annual Conference… Pre-Filled Syringes and SPONSORED BY: WORKSHOPS: 12TH CONFERENCE: 13TH - 14TH Injectable Drug Devices JAN 2021 Device design, regulatory and strategic pathways for parenteral drug delivery Copthorne Tara Hotel, London, UK PLUS TWO INTERACTIVE POST-CONFERENCE WORKSHOPS WEDNESDAY 20TH JANUARY 2021, COPTHORNE TARA HOTEL, LONDON, UK Workshop A: Digital Health – What are the real-world opportunities and potential barriers to adoption? Workshop Leader: Andrew Dundon, Founder, PharMechceutics Ltd Workshop B: Challenges and Drivers for Development of Long Acting Injectables Workshop Leader: Joël Richard, Chief Development Officer, MedinCell SMi Pharma www.pre-filled-syringes.com/oddad @SMiPharm Register online or fax your registration to +44 (0) 870 9090 712 #PFSSMi or call +44 (0) 870 9090 711 Copyright © 2020 Frederick Furness Publishing Ltd www.ondrugdelivery.com 47
Working towards a more sustainable future. At Noble, we feel it's our responsibility to help ensure a more sustainable future for our patients and customers, which is why we're proud to offer reusable training devices and recyclable packaging. © 2020 Noble International, LLC. All rights reserved. Noble Speaks Patient ™
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