Situasi COVId-19 di Jawa Timur sampai 5 Januari 2021

 
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Situasi COVId-19 di Jawa Timur sampai 5 Januari 2021
Situasi COVId-19 di Jawa Timur sampai 5 Januari 2021                                       1
             dan strategi Pengendaliannya
Satuan Gugus Tugas Kuratif Pengendalian COVID-19 Provinsi Jawa Timur
                          Satuan Gugus Tugas Percepatan Penanganan COVID-19 Jawa Timur
                                                                            1
                                     IG: @jatimpemprov | web: infocovid19.jatimprov.go.id
Situasi COVId-19 di Jawa Timur sampai 5 Januari 2021
Sumber data : www.endcoronavirus.org
BEATING COVID-19      Situasi Pandemi Covid-19 International   Desember 2020

NEARLY THERE

NEED TO TAKE ACTION
Situasi COVId-19 di Jawa Timur sampai 5 Januari 2021
COVID-19
     18
Situasi COVId-19 di Jawa Timur sampai 5 Januari 2021
Specific Tx
   NATURAL HISTORY of DISEASE
    And MODE OF TREATMENT                                      ANTIVIRAL …?
                                                                                       . Infeksi
                                                                                         Skunder
                                                          SUPPORTIVE                   . Pemberatan
                                         RECEPTOR
               PROKES                                        TX …?                        Co Morbid
                                           ACE-2                              TISSUE   . Gagal Napas
                                                      ?                       DAMAGE   . Gagal Organ

                                           IMMUNE
                                           RESPONSE
                                                           IMUNOMODULATOR…?
                                                           IMUNOSUPRESOR…….?
                                                           STEM CELL….?

Reff;
.New England journal of medicine, Sep 23-2020
.American society for microbiology, Agt 2020 ,
.P3 Covid -19 Kemkes Ed v                                                                Jnw 2020
Situasi COVId-19 di Jawa Timur sampai 5 Januari 2021
PROKES DOMINAN

                 Satgas Penanganan Covid-
11/5/2020          19: Bidang Perubahan     7
                          Perilaku
Situasi COVId-19 di Jawa Timur sampai 5 Januari 2021
Manajemen Perawatan Covid-19
                     Supervisi Nakes
                                                      Release                         Release                             Release
           01                                  • Swab PCR/ TCM (-)                                                   • Swab PCR/ TCM (-)
                                                                                 • Swab PCR/ TCM (-)
                                                 tanpa Gejala                                                          tanpa Gejala
                                                                                   tanpa Gejala
                             02
Isolasi Mandiri                     R. Karantina
                                                             03
                                                                     RS Lapangan
                                                                                                04       RS Rujukan
 • Swab (+) PCR/
                                                                • Swab (+) PCR                          • Swab (+) PCR /
   TCM tanpa gejala
                           Rujuk   • Swab (+) PCR         Rujuk                              Rujuk
    Rumah                                                         /TCM Gejala                             TCM,Probable,
                                     /TCM tanpa
    memenuhi syarat                                               ringan, non-                            Suspect dengan
                                     gejala, rumah
    isolasi                                                       komorbid.                               Gejala sedang-
                                     tidak memenuhi
 . Rapid (+) Ag/AB                                              • Discarded gejala                        Berat-Kritis (Rujukan
   Rm Memenuhi
                                     syarat isolasi
                                                                                                          Utama)
   sarat                           • Rapid Ag/Ab(+)               minimal
                                   • Discarded tanpa
                                                                     Tx                                 Tx
 Tx:                                 gejala
 • Isolasi                                                           • Isolasi                          • Isolasi
 • Monitor                         Tx                                • Treatment                        • Treatment
                                   • Isolasi                         • Monitor                          • Monitor
  Pelaksana
   • Masyarakat                    • Monitor
                                                                                                       Pelaksana         Discarded
                                                                  Pelaksana        Discarded
                                    Pelaksana                     • Pemerintah
                                                                                                     • Pemerintah
                                                                                                                    • Swab PCR/ TCM (+)
                                       • Masyarakat                              • Swab PCR/ TCM (+)                  Gejala minimal /
Reff . PPPC Kemkes ed. V               • Pemerintah                                tanpa Gejala                       tanpa gejala
Situasi COVId-19 di Jawa Timur sampai 5 Januari 2021
UU PRAKTIK KEDOKTERAN
                         (29 th 2004)
PASAL 50
Dokter atau dokter gigi dalam melaksanakan praktik
kedokteran mempunyai hak dan kwajiban :

a.     Memperoleh perlindungan hukum sepanjang melaksanakan
       tugas sesuai dengan standar profesi dan standar prosedur
       operasional;

b.     Memberikan pelayanan medis menurut standar profesi dan
       standar prosedur operasional ;
                Standard Profesi = Panduan Praktek Klinik

 UU 44 RS th 2009                    Pasal 32 Hak Pasien
 q.Menggugat dan/atau menuntut Rumah Sakit apabila Rumah Sakit
     diduga memberikan pelayanan yang tidak sesuai dengan standar
     baik secara perdata ataupun pidana; dan
                                      Pasal 29: Kewajiban RS
 s. Melindungi dan memberikan bantuan hukum bagi semua petugas Rumah Sakit dalam melaksanakan tugas
Situasi COVId-19 di Jawa Timur sampai 5 Januari 2021
Clinical Guideline ( CG ) :
(SPO Medik / PPK)
Is : Systematically develop statements to assist practitioner and
     patient decisions about appropriate heath care
     for specific clinical circumstances.

     ( Guideline are suggestions for care, not rules )

    The aim CG is to Improve Patient Outcome with
                     Base on Clinical Evidence ( EBM )

                                           Best Clinical Quality

               So, the C.G are a tool to assist in the art of decision making,
                                  do not constrain practitioners.

                                                         Richard Bowker et al. 2008 , Paul Shekelle,et al. 2015
Situasi COVId-19 di Jawa Timur sampai 5 Januari 2021
Template PPK RS.Dr Soetomo
                                                                                                                                     11.     Penelaah Kritis       a.       ........................................................................
                             Panduan Praktik Klinis                                                                                                                b.       ........................................................................
                                                                                                                                                                   c.       dst
                         SMF : .........................................                                                              12.    Indikator Medis       .......................................................................................................
                          RSUD Dr Soetomo, Surabaya                                                                                                                .......................................................................................................
                                         Tahun :                                                                                                                   .....................................................................................
                                                                                                                                      13.    Kepustakaan           a)       ........................................................................
               DIAGNOSA PENYAKIT (ICD-10) ..........................................                                                                               b)       ........................................................................
                                                                                                                                                                   c)       ........................................................................
1.    Pengertian           .......................................................................................................                                 d)       ........................................................................
      (Definisi)           ...........................................................................................                                             e)       ........................................................................
2.    Anamnesis            .......................................................................................................
                           .......................................................................................................
                           ...............................
3.    Pemeriksaan          .......................................................................................................
      Fisik                .......................................................................................................                         Komite Medik                                Disahkan
                           ...............................                                                                                                                                            Direktur R.S
4.    Kriteria             a.       ........................................................................
      Diagnosis            b.       ........................................................................
                           c.       dst
5.    Diagnosis            .......................................................................................................                         ………………..                                     . ……………….
      Kerja                ......................................................
6.    Diagnosis            a)       ........................................................................
      Banding              b)       ........................................................................
                           c)       ........................................................................
                           d)       ........................................................................
                           e)       ........................................................................
                                                                                                                                           Ket :
7.    Pemeriksaan          1.    .................. GR: ...
      Penunjang            2.    .................. GR: ...
                           3.    .................. GR: ...                                                                                GR : grade of recommendation
8.    Terapi               1.    .................. GR: ...
                           2.    .................. GR: ...                                                                                       1.A s/d 11. D
                           3.    .................. GR: ...
9.    Edukasi              1.    ........................................................................
                           2.    ........................................................................
                           3.    dst
10.   Prognosis            Ad vitam (hidup)                          : Dubia ad bonam/malam
                           Ad Sanationam (sembuh)                     : Dubia ad bonam/malam
                           Ad Fungsionam (fungsi)                     : Dubia ad bonam/malam
                                                                                                                                                               EBM-VBM
Situasi COVId-19 di Jawa Timur sampai 5 Januari 2021
Making
                                RECOMMENDATIONS
             Komponen yang dipertimbangkan dalam menentukan Rekomendasi
                               berbasis EB M / V B M

Clinical Evidence ( including
         consensus )                 Patient Views               Health Economics

                                   Clinical Judgement

                                   Recommendation

                Making Recommendation is an Art, not a Precise science .It is not Easy

                                                                     Monica lakhanpaul,2008
Quality of evidence

- Meta Analisis RCT
GRADE System ( th 2015 )
                                             have two components :
a. Two-level representation of the strength of recommendation : strong ( 1 ) and weak ( 2 )
b. Four-level or three representation of the quality of the evidence
   (high, moderate, low, and very low or high, moderate and low-very low )

● Strength of the recommendation:
a. Strong recommendation ( number 1 ) :
   is to do (or not do) something, where the benefits clearly outweigh the risks
   (or vice versa) for nearly all patients.
b. Weak/conditional recommendation ( number 2 ) :
   is made either when risks and benefits are more closely balanced or are more uncertain.

● Quality of evidence ( tingkat pembuktian ):
Assessment of evidence quality reflects confidence in the estimates of benefits, harms, and burdens can be implemented
with either four levels of evidence quality, or with three levels such that the “low” and “very low” categories are combined.
Three levels and uses a letter (A, B, or C) for high, moderate, or low/very low quality evidence.

High quality of evidence typically comes from well-performed randomized controlled trials or other overwhelming evidence (such as well-
executed observational studies with very large effects). Moderate-quality evidence typically comes from randomized trials with important
limitations, or from other study designs with special strength. Low-quality evidence typically comes from observational studies, or from controlled
trials with very serious limitations. Very low-quality evidence typically comes from nonsystematic observations, biologic reasoning, or
observational studies with serious limitations.
                                                                                                Clinical practice guidelines : Paul Shekelle et al, 2015
Grade of Recommendation
                                          ( GRADE System )
Grade of recommendation*    Clarity of risk/benefit                Quality of supporting evidence                 Implications

1A                          Benefits clearly outweigh risk and     Consistent evidence from well performed        Strong recommendation, can
Strong recommendation       burdens, or vice versa                 randomized, controlled trials or               apply to most patients in most
High quality evidence                                              overwhelming evidence of some other            circumstances without
                                                                   form. Further research is unlikely to change   reservation
                                                                   our confidence in the estimate of benefit
                                                                   and risk.
1B                          Benefits clearly outweigh risk and     Evidence from randomized, controlled trials    Strong recommendation, likely
Strong recommendation       burdens, or vice versa                 with important limitations (inconsistent       to apply to most patients
Moderate quality evidence                                          results, methodologic flaws, indirect or
                                                                   imprecise), or very strong evidence of some
                                                                   other form. Further research (if performed)
                                                                   is likely to have an impact on our
                                                                   confidence in the estimate of benefit and
                                                                   risk and may change the estimate.
1C                          Benefits appear to outweigh risk and   Evidence from observational studies,           Relatively strong
Strong recommendation       burdens, or vice versa                 unsystematic clinical experience, or from      recommendation; might
Low quality evidence                                               randomized, controlled trials with serious     change when higher quality
                                                                   flaws. Any estimate of effect is uncertain.    evidence becomes available

                                                                           Clinical practice guidelines : Paul Shekelle et al, 2015
Grade of recommendation*                      Clarity of risk/benefit                     Quality of supporting evidence                   Implications

 2A                                            Benefits closely balanced with risks and    Consistent evidence from well performed          Weak recommendation, best
 Weak recommendation                           burdens                                     randomized, controlled trials or overwhelming    action may differ depending on
 High quality evidence                                                                     evidence of some other form. Further research    circumstances or patients or
                                                                                           is unlikely to change our confidence in the      societal values
                                                                                           estimate of benefit and risk.

 2B                                            Benefits closely balanced with risks and    Evidence from randomized, controlled trials      Weak recommendation,
 Weak recommendation                           burdens, some uncertainty in the            with important limitations (inconsistent         alternative approaches likely to
 Moderate quality evidence                     estimates of benefits, risks and burdens    results, methodologic flaws, indirect or         be better for some patients under
                                                                                           imprecise), or very strong evidence of some      some circumstances
                                                                                           other form. Further research (if performed) is
                                                                                           likely to have an impact on our confidence in
                                                                                           the estimate of benefit and risk and may
                                                                                           change the estimate.

 2C                                            Uncertainty in the estimates of benefits,   Evidence from observational studies,             Very weak recommendation;
 Weak recommendation                           risks, and burdens; benefits may be         unsystematic clinical experience, or from        other alternatives may be equally
 Low quality evidence                          closely balanced with risks and burdens     randomized controlled trials with serious        reasonable
                                                                                           flaws. Any estimate of effect is uncertain.

*GRADE : Grading of Recommendations, Assessment, Development an Evaluation                                    Clinical practice guidelines : Paul Shekelle et al, 2015
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