Seale & Associates - CLINICAL LABORATORIES IN MEXICO 2021 - Seale & Associates
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GLOBAL INDUSTRY OUTLOOK The International Monetary Fund (IMF) estimated that the global GDP contracted 3.3% during 2020, and is anticipating a 6.0% growth for 2021 The unprecedented public health emergency has put pathologists and laboratory professionals at the front lines of the pandemic, allowing patients to receive a proper diagnosis and treatment in an efficient manner Global health expenditure reached US$8.3 trillion in 2020, and it is expected to grow 5.8% in 2021, to US$8.8 trillion, by the end of the year According to the World Health Organization (WHO), around 5.0% of patients face diagnostic errors every year, emphasizing the need for technological implementations in laboratories in order to reduce error margins Clinical Laboratories Sources: American Society for Clinical Pathology, Seale & Associates 2021 IHS Markit, IMF, WHO Creative Solutions. Trusted Advice.
HIGHLIGHTS & TRENDS • The global clinical laboratories industry registered a value of US$96.8 billion in 2020, and is expected to reach US$135.5 billion by 2027, having a 4.9% CAGR • The rise in the geriatric population, the high prevalence of cardiovascular, neurological and chronic diseases, and the increasing demand for early diagnoses, are among the main drivers for the industry’s growth in the upcoming years • Further technological advances are expected in clinical pathology, anatomic pathology, clinical microbiology and hematology • Implementing point of care (POC) testing for infections, for example, will continue to reduce unnecessary clinic visits, prescription costs, and support further patient engagement • Larger databases will help better diagnose patients, by being able to use the patient’s clinical history • The Covid-19 pandemic has forced clinical laboratories to increase their testing capacity, reminding us that data is the most accurate way to understand the pandemic’s development Clinical Laboratories Sources: Allied Market Research, Clinical Lab Seale & Associates 2021 Manager, IndustryARC, ReportLinkers Creative Solutions. Trusted Advice.
INDUSTRY SEGMENTATION BY TEST TYPE Clinical Chemical Testing: Measures concentrations or activities of substances in body fluids Microbiology Testing: Detects and identifies the presence of microorganisms Hematology Testing: Evaluates the conditions of blood, blood proteins, and blood-producing organs Immunology Testing: Employs antigens and antibodies to detect abnormalities in the immune system Cytology Testing: Examines specific body cells using special equipment, like microscopes Genetic Testing: Identifies changes in DNA sequence or chromosome structures Drug Abuse Testing: Looks for the presence of illegal or prescribed substances in body fluids Clinical Laboratories Sources: IndustryARC, Johns Hopkins Seale & Associates 2021 Medicine, National Institutes of Health Creative Solutions. Trusted Advice.
COVID-19 Antigen tests: Detect a protein that is part of the coronavirus. They are popular for their low costs and quick results, but tend to be less accurate Molecular tests (Polymerase Chain Reaction): Detect genetic material of the coronavirus. PCR tests have become the most popular and accurate option, although they remain perfectible Antibody tests: Use blood samples to look for antibodies produced by a person’s immune system. These can only detect if someone had a past COVID-19 infection COVID-19 TEST TRACKER April 9th, 2021 Daily tests per Total tests per Country 1,000 people 1,000 people 7-day rolling average United Kingdom 11.89 1,912.01 Italy 4.39 862.0 Hong Kong 3.36 1,439.09 Chile 2.96 610.68 USA 2.75 1,163.33 India 0.84 184.09 Japan 0.41 76.80 Mexico 0.07 44.79 Clinical Laboratories Sources: American Society for Clinical Pathology, Seale & Associates 2021 Our World in Data, UC Davis Health Creative Solutions. Trusted Advice.
KEY INDUSTRY INSIGHTS: MEXICO There are a total of 7,624 clinical laboratories in Mexico, 456 more establishments than in 2019 Clinical laboratories in Mexico registered an estimated US$3.2 billion in sales during 2020 The clinical laboratories industry in Mexico currently employs 87,981 people, 6.4% more than in 2019 Clinical Laboratory Industry Sales in Mexico (US$ million) $3,529.0 $3,500 $3,184.0 $3,000 $2,860.0 $2,582.0 $2,500 $2,333.0 $2,000 $1,500 $1,000 $500 $0 2017 2018 2019 2020 2021 Clinical Laboratories Sources: Barnes Reports Seale & Associates 2021 Creative Solutions. Trusted Advice.
GLOBAL INDUSTRY – COMPARABLE PUBLIC COMPANIES Annual Average Last Update Market Enterprise Revenue EBITDA EV/EBITDA Apr. 8, 2021 Company Country Cap. Value US$MM Margin EV/ EV/ US$MM US$MM 2019 2020 EBITDA Revenue Akumin Inc. USA $232 $737 $246 18.8% 11.3x 8.8x 10.2x 3.0x BML, Inc. JPN $1,350 $884 $1,222 14.6% 5.5x 5.4x 5.3x 0.8x Capitol Health Limited AUS $294 $343 $122 20.2% 8.7x 8.6x 11.0x 2.8x Centro de Imagem BRA $195 $342 $179 5.2% 11.8x 13.6x NR 2.1x Diagnósticos S.A. DaVita Inc. USA $11,690 $24,053 $11,551 20.3% 8.2x 7.1x 7.9x 2.1x Eurofins Scientific SE LUX $19,338 $22,038 $6,653 23.4% 13.4x 14.8x 13.2x 3.4x Falco Holdings Co., Ltd. JPN $158 $109 $410 6.5% 5.3x 7.4x 4.4x 0.3x Fleury S.A. BRA $1,516 $1,798 $572 24.5% 10.5x 13.6x 11.8x 3.4x H.U. Group Holdings, Inc. JPN $1,811 $2,055 $2,015 15.1% 8.1x 10.2x 7.8x 1.1x Healius Limited AUS $1,947 $3,021 $1,338 12.5% 14.4x 11.4x 9.9x 2.3x Instituto Hermes Pardini S.A. BRA $472 $548 $288 17.1% 12.2x 12.9x 10.3x 2.1x Integral Diagnostics Limited AUS $727 $911 $243 22.3% 13.3x 15.5x 14.6x 3.8x Laboratory Corporation of USA $24,607 $30,064 $13,979 25.7% 9.8x 9.0x 7.8x 2.2x America Holdings Med Life S.A. ROM $340 $491 $273 17.0% 10.2x 8.5x 9.1x 1.9x Medicover AB (publ) SWE $3,475 $3,846 $1,221 11.5% 18.0x 16.1x NR 3.3x Quest Diagnostics USA $16,903 $20,685 $9,437 26.2% 10.4x 10.0x 7.3x 2.2x Incorporated RadNet, Inc. USA $1,109 $2,284 $1,098 12.0% 9.0x 8.3x 9.2x 2.1x Sonic Healthcare Limited AUS $13,109 $15,456 $6,113 21.0% 15.8x 14.0x 10.3x 2.6x Terveystalo Oyj FIN $1,864 $2,449 $1,207 11.7% 12.4x 11.5x 13.1x 2.1x Voxel S.A. POL $120 $154 $88 19.5% 7.5x 9.3x 7.9x 1.8x NR: Not Relevant Mean 10.8x 10.8x 9.5x 2.2x Median 10.5x 10.2x 9.5x 2.2x Clinical Laboratories Sources: Capital IQ, S&P Market Intelligence Seale & Associates 2021 Creative Solutions. Trusted Advice.
REPRESENTATIVE GLOBAL INDUSTRY TRANSACTIONS Size EV/ EV/ Date Target Country Description Buyer Stake % US$MM EBITDA Revenue Provides point-of-care diagnostic Jan-21* LifeAssays AB (publ) SWE AegirBio AB (publ) 100.0% $18.1 NR NR testing services Nov-20 Direct Radiology Pty Ltd AUS Offers diagnostic imaging services Capitol Health Limited 100.0% $10.5 10.2x 2.4x Global Diagnostics (Ireland) Provides diagnostic imaging services to Nov-20 IRL Medica Group Plc 100.0% $23.4 18.2x 2.7x Limited public and private hospitals Oct-20 AZ-Tech Radiology, LLC USA Provides digital imaging services RadNet, Inc. 100.0% $5.5 - - Offers radiology, interventional Infratil Limited; HRL Morrison & Co Oct-20* Qscan Services Pty Ltd AUS radiology, and other patient care Limited; Morrison & Co Growth 100.0% $523.6 - - services Infrastructure Fund Provides radiological diagnostic Jul-20 X-Ray One Srl ITA imaging services and outpatient Garofalo Health Care S.p.A. 100.0% $15.3 7.6x 1.8x services Jun-20 Ascot Radiology Limited NZL Provides radiology services Integral Diagnostics Limited 100.0% $35.5 - - Mar-20 Genelex Corporation USA Operates as a DNA testing laboratory Invitae Corporation 100.0% $12.0 - - Provides diagnostics and biomarker Feb-20 Paradigm Diagnostics, Inc. USA driven clinical trial services for cancer Exact Sciences Corporation 100.0% $40.4 - - patients Jan-20 Blueprint Genetics Oy FIN Provides clinical genetics testing Quest Diagnostics Incorporated 100.0% $111.0 - - Centro De Analise E Tipagem Operates a genetics and molecular Nov-19 BRA Eurofins Scientific SE 100.0% $10.8 - 1.2x De Genomas Ltda. biology laboratory Five Diagnostic Centers of Comprises outpatient diagnostic Aug-19 USA Akumin Inc. 100.0% $11.0 - 0.8x Southwest X-Ray, LP imaging centers Apr-19 TIC Acquisition Holdings, LLC USA Owns and operates imaging centers Akumin Corp. 100.0% $47.1 - - Provides biochemical and molecular Laboratory Corporation of America Mar-19 Medical Neurogenetics, LLC USA 100.0% - - - testing services Holdings Provides diagnostic, prognostic, and Dec-18 Aurora Diagnostics, LLC USA Sonic Healthcare Limited 100.0% $540.0 - - therapeutic information and services Laboratory Services Business Nov-18 of Boyce & Bynum Pathology USA Comprises laboratory services Quest Diagnostics Incorporated 100.0% $80.0 - - Laboratories, P.C. Four Freestanding, Outpatient Nov-18 Diagnostic Imaging Centers in USA Comprises diagnostic imaging centers Akumin Inc. 100.0% $12.1 - - Broward County The Tohkai Cytopathology Offers inspection and diagnosis for Oct-18 JPN BML, Inc. 100.0% - - - Institute cancer treatments Provides specialized oncology Oct-18 Genoptix, Inc. USA NeoGenomics Laboratories, Inc. 100.0% $138.7 - - diagnostics services U.S. Laboratory Services Comprises clinical laboratory testing Sep-18 Business of Oxford Immunotec USA services for tuberculosis and tick-borne Quest Diagnostics Incorporated 100.0% $170.0 - - Global PLC diseases Operates as a reference laboratory for Sep-18 ReproSource, Inc. USA Quest Diagnostics Incorporated 100.0% $35.0 - - infertility diagnostics 11 diagnostic centers from Rose Comprises health care and diagnostic Aug-18 USA Akumin Inc. 100.0% $25.0 - - Radiology Centers, Inc. centers NR: Not Relevant *Announced Clinical Laboratories Sources: Capital IQ, S&P Market Intelligence Seale & Associates 2021 Creative Solutions. Trusted Advice.
REPRESENTATIVE GLOBAL INDUSTRY TRANSACTIONS Size EV/ EV/ Date Target Country Description Buyer Stake % US$MM EBITDA Revenue Five Imaging Centers In Fresno, Apr-18 USA Comprises imaging centers RadNet, Inc. 100.0% $8.3 - - California Operates a network of medical imaging Jan-18 I-MED Holdings Pty Limited AUS Permira Advisers Ltd. 100.0% $1,012.7 - 1.8x clinics Operates as a mobile health screening Jan-18 HealthFair USA, Inc. USA Community Care Health Network, Inc. 100.0% $160.0 - 3.6x company Specialist Radiology Group/ May-18 Trinity MRI/ Cavendish NZL Operates as a radiology clinic Integral Diagnostics Limited 100.0% $74.9 - - Radiology Operates as a clinical laboratory and Oct-17 Cleveland HeartLab, Inc. USA cardiovascular disease management Quest Diagnostics Incorporated 100.0% $94.0 - - company Operates anatomic pathology Miraca Life Sciences, Inc. Sep-17 USA laboratories that provide diagnostic Avista Capital Holdings, L.P. 100.0% $175.6 - - (nka:Inform Diagnostics, Inc.) services Diagnostic Imaging Associates, Aug-17 USA Owns and operates imaging centers RadNet, Inc. 100.0% $14.5 - - P.A. Provides genetic screening of inherited Jul-17 Good Start Genetics, Inc. USA Invitae Corporation 100.0% $40.0 - 1.8x diseases Innovation Network Corporation of Japan Provides clinical diagnostics testing Jul-17 Ambry Genetics Corporation USA (nka:Japan Investment Corporation); 100.0% $1,000.0 - - services for genetic diseases Konica Minolta Healthcare Americas, Inc. Capitol Health Limited, New Jun-17 AUS Comprises a radiology facility I-MED Holdings Pty Limited 100.0% $61.2 - - South Wales Radiology Assets Cedic – Centro de Diagnósticos por Mar-17 Radiologistas Associados Ltda. BRA Provides radiology services Imagem de Cuiabá Ltda.; Centro de 100.0% $29.3 6.9x - Imagem Diagnósticos S.A. West Pacific Medical Provides clinical, pathology, and Feb-17 USA Sonic Healthcare Limited 100.0% - - - Laboratory, LLC molecular testing services Mean 10.7x 2.0x Median 8.9x 1.8x Clinical Laboratories Sources: Capital IQ, S&P Market Intelligence Seale & Associates 2021 Creative Solutions. Trusted Advice.
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Contact Information Seale & Associates James A. Seale President jseale@sealeassociates.com Creative Solutions. Trusted Advice. Brett M. Carmel Since 1999, Seale & Associates has been the trusted advisor Senior Managing Director bcarmel@sealeassociates.com to respected public and private companies from around the Felipe Bueno Viesca world. Seale is a global investment bank with extensive Senior Director fbueno@sealeassociates.com experience in mergers and acquisitions (M&A), corporate Sergio Garcia del Bosque finance advisory, and enterprise level strategy consulting with Managing Director sgarcia@sealeassociates.com a track record of success in a diverse range of industries. Our Carlos Hernandez experienced team of professionals are committed to serving Managing Director chernandez@sealeassociates.com clients with excellence and integrity, while offering innovative Alejandro Montemayor ideas and solutions to address complex transactions. Vice President amontemayor@sealeassociates.com Armando Rios ADVISOR TO LEADING COMPANIES WORLDWIDE Associate arios@sealeassociates.com Fernanda Esparza Analyst fesparza@sealeassociates.com Sofia Felix Business Development sfelix@sealeassociates.com Miguel Leal Business Development mleal@sealeassociates.com Andre de Lachica Junior Analyst adelachica@sealeassociates.com Andre Leroy Junior Analyst lleroy@sealeassociates.com Carlos Bonilla Junior Analyst CONTACT INFORMATION cbonilla@sealeassociates.com Daniela Verdugo Junior Analyst dverdugo@sealeassociates.com Headquarters 901 N. Glebe Road Jose Pablo Arronte Junior Analyst 5th Floor jarronte@sealeassociates.com Arlington, Virginia Regina Labardini +1 (703) 294 6770 Junior Analyst rlabardini@sealeassociates.com Please contact us if you would like further information about M&A trends and/or specific transaction multiples for your industry Washington, D.C. | Miami | Mexico City | Monterrey www.sealeassociates.com
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