Seale & Associates - CLINICAL LABORATORIES IN MEXICO 2021 - Seale & Associates

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Seale & Associates - CLINICAL LABORATORIES IN MEXICO 2021 - Seale & Associates
Seale & Associates
  Creative Solutions. Trusted Advice.

                                           CLINICAL
                                        LABORATORIES
                                          IN MEXICO

                                            2021
Seale & Associates - CLINICAL LABORATORIES IN MEXICO 2021 - Seale & Associates
GLOBAL INDUSTRY OUTLOOK

                         The International Monetary Fund (IMF) estimated that the
                         global GDP contracted 3.3% during 2020, and is anticipating
                         a 6.0% growth for 2021

                         The unprecedented public health emergency has put
                         pathologists and laboratory professionals at the front lines of
                         the pandemic, allowing patients to receive a proper diagnosis
                         and treatment in an efficient manner

                         Global health expenditure reached US$8.3 trillion in 2020,
                         and it is expected to grow 5.8% in 2021, to US$8.8 trillion, by
                         the end of the year

                         According to the World Health Organization (WHO), around
                         5.0% of patients face diagnostic errors                    every year,
                         emphasizing the need for technological implementations in
                         laboratories in order to reduce error margins

Clinical Laboratories         Sources: American Society for Clinical Pathology,    Seale & Associates
2021                                     IHS Markit, IMF, WHO                     Creative Solutions. Trusted Advice.
Seale & Associates - CLINICAL LABORATORIES IN MEXICO 2021 - Seale & Associates
HIGHLIGHTS & TRENDS
         •     The global clinical laboratories industry registered a value of US$96.8
               billion in 2020, and is expected to reach US$135.5 billion by 2027, having
               a 4.9% CAGR

         •     The rise in the geriatric population, the high prevalence of cardiovascular,
               neurological and chronic diseases, and the increasing demand for early
               diagnoses, are among the main drivers for the industry’s growth in the
               upcoming years

         •     Further technological advances are expected in clinical pathology,
               anatomic pathology, clinical microbiology and hematology

         •     Implementing point of care (POC) testing for infections, for example, will
               continue to reduce unnecessary clinic visits, prescription costs, and support
               further patient engagement

         •     Larger databases will help better diagnose patients, by being able to use
               the patient’s clinical history

         •     The Covid-19 pandemic has forced clinical laboratories to increase their
               testing capacity, reminding us that data is the most accurate way to
               understand the pandemic’s development

Clinical Laboratories                 Sources: Allied Market Research, Clinical Lab    Seale & Associates
2021                                     Manager, IndustryARC, ReportLinkers          Creative Solutions. Trusted Advice.
Seale & Associates - CLINICAL LABORATORIES IN MEXICO 2021 - Seale & Associates
INDUSTRY SEGMENTATION BY TEST TYPE

    Clinical Chemical Testing: Measures concentrations or
    activities of substances in body fluids

                                             Microbiology Testing: Detects and identifies the
                                                                             presence of microorganisms

    Hematology Testing: Evaluates the conditions of blood,
    blood proteins, and blood-producing organs

                                 Immunology Testing: Employs antigens and antibodies to
                                                      detect abnormalities in the immune system

    Cytology Testing: Examines specific body cells using
    special equipment, like microscopes

                                   Genetic Testing: Identifies changes in DNA sequence or
                                                                                 chromosome structures

    Drug Abuse Testing: Looks for the presence of illegal or
    prescribed substances in body fluids

Clinical Laboratories              Sources: IndustryARC, Johns Hopkins                   Seale & Associates
2021                               Medicine, National Institutes of Health              Creative Solutions. Trusted Advice.
COVID-19

                                  Antigen tests: Detect a protein that is part of the coronavirus.
                                  They are popular for their low costs and quick results, but tend
                                  to be less accurate

                                           Molecular tests (Polymerase Chain Reaction): Detect
                                           genetic material of the coronavirus. PCR tests have
                                           become the most popular and accurate option,
                                           although they remain perfectible

                                  Antibody tests: Use blood samples to look for antibodies
                                  produced by a person’s immune system. These can only
                                  detect if someone had a past COVID-19 infection

        COVID-19 TEST TRACKER
        April 9th, 2021
                                                Daily tests per                        Total tests per
                        Country                 1,000 people                            1,000 people
                                               7-day rolling average

        United Kingdom                                 11.89                             1,912.01

        Italy                                           4.39                               862.0

        Hong Kong                                       3.36                             1,439.09

        Chile                                           2.96                              610.68

        USA                                             2.75                             1,163.33

        India                                           0.84                              184.09

        Japan                                           0.41                               76.80

        Mexico                                          0.07                               44.79

Clinical Laboratories              Sources: American Society for Clinical Pathology,          Seale & Associates
2021                                    Our World in Data, UC Davis Health                   Creative Solutions. Trusted Advice.
KEY INDUSTRY INSIGHTS: MEXICO

                                 There are a total of 7,624 clinical laboratories in Mexico, 456
                                 more establishments than in 2019

                                 Clinical laboratories in Mexico registered an estimated
                                 US$3.2 billion in sales during 2020

                                 The clinical laboratories industry in Mexico currently employs
                                 87,981 people, 6.4% more than in 2019

      Clinical Laboratory Industry Sales in Mexico (US$ million)

                                                                                   $3,529.0
                 $3,500
                                                                        $3,184.0

                 $3,000                                   $2,860.0
                                          $2,582.0
                 $2,500       $2,333.0

                 $2,000

                 $1,500

                 $1,000

                   $500

                        $0
                               2017        2018             2019         2020        2021

Clinical Laboratories                         Sources: Barnes Reports               Seale & Associates
2021                                                                               Creative Solutions. Trusted Advice.
GLOBAL INDUSTRY – COMPARABLE PUBLIC COMPANIES
                                                                                     Annual Average         Last Update
                                        Market Enterprise
                                                          Revenue           EBITDA     EV/EBITDA            Apr. 8, 2021
                  Company       Country  Cap.    Value
                                                           US$MM            Margin                         EV/        EV/
                                        US$MM   US$MM                                 2019    2020
                                                                                                         EBITDA Revenue

Akumin Inc.                      USA      $232        $737        $246       18.8%    11.3x   8.8x        10.2x           3.0x

BML, Inc.                        JPN     $1,350       $884       $1,222      14.6%    5.5x    5.4x         5.3x           0.8x

Capitol Health Limited           AUS      $294        $343        $122       20.2%    8.7x    8.6x        11.0x           2.8x
Centro de Imagem
                                 BRA      $195        $342        $179       5.2%     11.8x   13.6x         NR            2.1x
Diagnósticos S.A.

DaVita Inc.                      USA    $11,690     $24,053     $11,551      20.3%    8.2x    7.1x         7.9x           2.1x

Eurofins Scientific SE           LUX    $19,338     $22,038      $6,653      23.4%    13.4x   14.8x       13.2x           3.4x

Falco Holdings Co., Ltd.         JPN      $158        $109        $410       6.5%     5.3x    7.4x         4.4x           0.3x

Fleury S.A.                      BRA     $1,516      $1,798       $572       24.5%    10.5x   13.6x       11.8x           3.4x

H.U. Group Holdings, Inc.        JPN     $1,811      $2,055      $2,015      15.1%    8.1x    10.2x        7.8x           1.1x

Healius Limited                  AUS     $1,947      $3,021      $1,338      12.5%    14.4x   11.4x        9.9x           2.3x

Instituto Hermes Pardini S.A.    BRA      $472        $548        $288       17.1%    12.2x   12.9x       10.3x           2.1x

Integral Diagnostics Limited     AUS      $727        $911        $243       22.3%    13.3x   15.5x       14.6x           3.8x

Laboratory Corporation of
                                 USA    $24,607     $30,064     $13,979      25.7%    9.8x    9.0x         7.8x           2.2x
America Holdings

Med Life S.A.                    ROM      $340        $491        $273       17.0%    10.2x   8.5x         9.1x           1.9x

Medicover AB (publ)              SWE     $3,475      $3,846      $1,221      11.5%    18.0x   16.1x         NR            3.3x
Quest Diagnostics
                                 USA    $16,903     $20,685      $9,437      26.2%    10.4x   10.0x        7.3x           2.2x
Incorporated

RadNet, Inc.                     USA     $1,109      $2,284      $1,098      12.0%    9.0x    8.3x         9.2x           2.1x

Sonic Healthcare Limited         AUS    $13,109     $15,456      $6,113      21.0%    15.8x   14.0x       10.3x           2.6x

Terveystalo Oyj                  FIN     $1,864      $2,449      $1,207      11.7%    12.4x   11.5x       13.1x           2.1x

Voxel S.A.                       POL      $120        $154        $88        19.5%    7.5x    9.3x         7.9x           1.8x
NR: Not Relevant                                                               Mean 10.8x     10.8x        9.5x           2.2x
                                                                              Median 10.5x    10.2x        9.5x           2.2x

Clinical Laboratories               Sources: Capital IQ, S&P Market Intelligence                Seale & Associates
2021                                                                                           Creative Solutions. Trusted Advice.
REPRESENTATIVE GLOBAL INDUSTRY TRANSACTIONS
                                                                                                                                                 Size          EV/         EV/
  Date                    Target             Country                Description                                     Buyer            Stake %
                                                                                                                                                US$MM        EBITDA      Revenue

                                                          Provides point-of-care diagnostic
 Jan-21*     LifeAssays AB (publ)            SWE                                               AegirBio AB (publ)                    100.0%      $18.1         NR           NR
                                                                  testing services

 Nov-20      Direct Radiology Pty Ltd        AUS         Offers diagnostic imaging services    Capitol Health Limited                100.0%      $10.5        10.2x         2.4x

             Global Diagnostics (Ireland)              Provides diagnostic imaging services to
 Nov-20                                      IRL                                               Medica Group Plc                      100.0%      $23.4        18.2x         2.7x
             Limited                                         public and private hospitals

 Oct-20      AZ-Tech Radiology, LLC          USA          Provides digital imaging services    RadNet, Inc.                          100.0%       $5.5           -           -

                                                           Offers radiology, interventional    Infratil Limited; HRL Morrison & Co
 Oct-20*     Qscan Services Pty Ltd          AUS          radiology, and other patient care    Limited; Morrison & Co Growth         100.0%      $523.6          -           -
                                                                      services                 Infrastructure Fund
                                                          Provides radiological diagnostic
  Jul-20     X-Ray One Srl                   ITA          imaging services and outpatient      Garofalo Health Care S.p.A.           100.0%      $15.3         7.6x         1.8x
                                                                     services

 Jun-20      Ascot Radiology Limited         NZL            Provides radiology services        Integral Diagnostics Limited          100.0%      $35.5           -           -

 Mar-20      Genelex Corporation             USA        Operates as a DNA testing laboratory Invitae Corporation                     100.0%      $12.0           -           -

                                                        Provides diagnostics and biomarker
 Feb-20      Paradigm Diagnostics, Inc.      USA       driven clinical trial services for cancer Exact Sciences Corporation          100.0%      $40.4           -           -
                                                                        patients

 Jan-20      Blueprint Genetics Oy           FIN          Provides clinical genetics testing   Quest Diagnostics Incorporated        100.0%      $111.0          -           -

             Centro De Analise E Tipagem                 Operates a genetics and molecular
 Nov-19                                      BRA                                               Eurofins Scientific SE                100.0%      $10.8           -          1.2x
             De Genomas Ltda.                                   biology laboratory

             Five Diagnostic Centers of                   Comprises outpatient diagnostic
 Aug-19                                      USA                                               Akumin Inc.                           100.0%      $11.0           -          0.8x
             Southwest X-Ray, LP                                 imaging centers

  Apr-19     TIC Acquisition Holdings, LLC   USA        Owns and operates imaging centers      Akumin Corp.                          100.0%      $47.1           -           -

                                                        Provides biochemical and molecular     Laboratory Corporation of America
 Mar-19      Medical Neurogenetics, LLC      USA                                                                                     100.0%        -             -           -
                                                                 testing services              Holdings

                                                        Provides diagnostic, prognostic, and
 Dec-18      Aurora Diagnostics, LLC         USA                                               Sonic Healthcare Limited              100.0%      $540.0          -           -
                                                        therapeutic information and services

             Laboratory Services Business
 Nov-18      of Boyce & Bynum Pathology      USA           Comprises laboratory services       Quest Diagnostics Incorporated        100.0%      $80.0           -           -
             Laboratories, P.C.
             Four Freestanding, Outpatient
 Nov-18      Diagnostic Imaging Centers in   USA       Comprises diagnostic imaging centers Akumin Inc.                              100.0%      $12.1           -           -
             Broward County

             The Tohkai Cytopathology                    Offers inspection and diagnosis for
 Oct-18                                      JPN                                               BML, Inc.                             100.0%        -             -           -
             Institute                                            cancer treatments

                                                           Provides specialized oncology
 Oct-18      Genoptix, Inc.                  USA                                               NeoGenomics Laboratories, Inc.        100.0%      $138.7          -           -
                                                               diagnostics services

             U.S. Laboratory Services                   Comprises clinical laboratory testing
 Sep-18      Business of Oxford Immunotec    USA       services for tuberculosis and tick-borne Quest Diagnostics Incorporated       100.0%      $170.0          -           -
             Global PLC                                                diseases

                                                       Operates as a reference laboratory for
 Sep-18      ReproSource, Inc.               USA                                              Quest Diagnostics Incorporated         100.0%      $35.0           -           -
                                                               infertility diagnostics

             11 diagnostic centers from Rose            Comprises health care and diagnostic
 Aug-18                                      USA                                             Akumin Inc.                             100.0%      $25.0           -           -
             Radiology Centers, Inc.                                 centers

NR: Not Relevant
*Announced

Clinical Laboratories                                         Sources: Capital IQ, S&P Market Intelligence                                      Seale & Associates
2021                                                                                                                                           Creative Solutions. Trusted Advice.
REPRESENTATIVE GLOBAL INDUSTRY TRANSACTIONS
                                                                                                                                                     Size          EV/         EV/
 Date                  Target              Country                Description                                   Buyer                    Stake %
                                                                                                                                                    US$MM        EBITDA      Revenue

          Five Imaging Centers In Fresno,
 Apr-18                                   USA             Comprises imaging centers           RadNet, Inc.                               100.0%       $8.3           -           -
          California

                                                     Operates a network of medical imaging
 Jan-18   I-MED Holdings Pty Limited       AUS                                             Permira Advisers Ltd.                         100.0%     $1,012.7         -          1.8x
                                                                    clinics

                                                     Operates as a mobile health screening
 Jan-18   HealthFair USA, Inc.             USA                                             Community Care Health Network, Inc.           100.0%      $160.0          -          3.6x
                                                                   company

          Specialist Radiology Group/
May-18    Trinity MRI/ Cavendish           NZL           Operates as a radiology clinic       Integral Diagnostics Limited               100.0%      $74.9           -           -
          Radiology
                                                      Operates as a clinical laboratory and
 Oct-17   Cleveland HeartLab, Inc.         USA        cardiovascular disease management       Quest Diagnostics Incorporated             100.0%      $94.0           -           -
                                                                   company
                                                         Operates anatomic pathology
          Miraca Life Sciences, Inc.
Sep-17                                     USA        laboratories that provide diagnostic    Avista Capital Holdings, L.P.              100.0%      $175.6          -           -
          (nka:Inform Diagnostics, Inc.)
                                                                    services

          Diagnostic Imaging Associates,
 Aug-17                                    USA        Owns and operates imaging centers       RadNet, Inc.                               100.0%      $14.5           -           -
          P.A.

                                                     Provides genetic screening of inherited
 Jul-17   Good Start Genetics, Inc.        USA                                               Invitae Corporation                         100.0%      $40.0           -          1.8x
                                                                   diseases

                                                                                              Innovation Network Corporation of Japan
                                                      Provides clinical diagnostics testing
 Jul-17   Ambry Genetics Corporation       USA                                                (nka:Japan Investment Corporation);        100.0%     $1,000.0         -           -
                                                         services for genetic diseases
                                                                                              Konica Minolta Healthcare Americas, Inc.

          Capitol Health Limited, New
 Jun-17                                    AUS           Comprises a radiology facility       I-MED Holdings Pty Limited                 100.0%      $61.2           -           -
          South Wales Radiology Assets

                                                                                              Cedic – Centro de Diagnósticos por
Mar-17    Radiologistas Associados Ltda.   BRA            Provides radiology services         Imagem de Cuiabá Ltda.; Centro de          100.0%      $29.3         6.9x          -
                                                                                              Imagem Diagnósticos S.A.

          West Pacific Medical                          Provides clinical, pathology, and
Feb-17                                     USA                                                Sonic Healthcare Limited                   100.0%        -             -           -
          Laboratory, LLC                                  molecular testing services

                                                                                                                                                        Mean      10.7x         2.0x
                                                                                                                                                       Median      8.9x         1.8x

Clinical Laboratories                                       Sources: Capital IQ, S&P Market Intelligence                                            Seale & Associates
2021                                                                                                                                               Creative Solutions. Trusted Advice.
REPRESENTATIVE GLOBAL ENGAGEMENTS

            has sold                                                                                                                           has sold

                     to                                          has acquired              has acquired               has acquired                               has been acquired by
                                                                                                                                                  to

     GE Power                                                                                                                                    and
     Systems                                                                                                                               JBI Holding SAS

                                                                                                                                                                    Grupo Educativo
                                                                                                                                                                         IEJV

has partnered with                                                                                                    has acquired

                                                               has acquired                has acquired
                                                                                                                  The Zinc Recycling
                                                                                                                                          has been acquired by
                                                                                                                      Business
                                                                                                                            of
  a subsidiary of                                                                                                                                                has been acquired by

         a subsidiary of
                                                                                       has sold the North                                                               has sold
                                                                                           American
                                                                  has been            guarding business of                                has been acquired by            and
               has sold                                        recapitalized by                                       has acquired
                                                                                                                                                                           to
   A division of Carrier Commercial Refrigeration, Inc.
                                                                                               to
                       to
                    and

                                                                                      intelectiva             ®

                                                                                          has acquired
                                                                  has sold                                                                     has acquired       Holding company of
                                                             Cosmocel Química
                                                                                                                  has sold its concrete
                                                                      to
                                                                                                                  pumping business to
has been acquired by                                                                                                                                             has acquired a majority
                                                                                      KFC Costa Rica                                        dealerships from            stake in

                                                              a business unit of              from

                                                                                                                                                                         has sold
                                                                                                                                                                    Its sanitaryware
                                                                                         has acquired                                                                  businesses
                                                                                                                                             has merged its
                                                           Grupo Galaz, S.A de C.V.                               has been acquired by      beverage division
has been acquired by                                                                  Workshop and store in
                                                                                                                                                  with                     and
                                                            has been acquired by        Mexico City from

                                                                                                                                                                            to

                                                                  Washington, D.C. | Miami | Mexico City | Monterrey
Contact Information

                Seale & Associates                                                           James A. Seale
                                                                                               President
                                                                                       jseale@sealeassociates.com
                  Creative Solutions. Trusted Advice.
                                                                                            Brett M. Carmel
Since 1999, Seale & Associates has been the trusted advisor                             Senior Managing Director
                                                                                      bcarmel@sealeassociates.com
to respected public and private companies from around the
                                                                                          Felipe Bueno Viesca
world. Seale is a global investment bank with extensive                                     Senior Director
                                                                                      fbueno@sealeassociates.com
experience in mergers and acquisitions (M&A), corporate
                                                                                         Sergio Garcia del Bosque
finance advisory, and enterprise level strategy consulting with                             Managing Director
                                                                                       sgarcia@sealeassociates.com
a track record of success in a diverse range of industries. Our
                                                                                            Carlos Hernandez
experienced team of professionals are committed to serving                                 Managing Director
                                                                                     chernandez@sealeassociates.com
clients with excellence and integrity, while offering innovative
                                                                                         Alejandro Montemayor
ideas and solutions to address complex transactions.                                          Vice President
                                                                                    amontemayor@sealeassociates.com

                                                                                              Armando Rios
ADVISOR TO LEADING COMPANIES WORLDWIDE                                                          Associate
                                                                                        arios@sealeassociates.com

                                                                                            Fernanda Esparza
                                                                                                Analyst
                                                                                      fesparza@sealeassociates.com

                                                                                               Sofia Felix
                                                                                         Business Development
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                                                                                              Miguel Leal
                                                                                        Business Development
                                                                                       mleal@sealeassociates.com

                                                                                            Andre de Lachica
                                                                                              Junior Analyst
                                                                                     adelachica@sealeassociates.com

                                                                                               Andre Leroy
                                                                                              Junior Analyst
                                                                                       lleroy@sealeassociates.com

                                                                                              Carlos Bonilla
                                                                                              Junior Analyst
CONTACT INFORMATION                                                                   cbonilla@sealeassociates.com

                                                                                           Daniela Verdugo
                                                                                            Junior Analyst
                                                                                     dverdugo@sealeassociates.com
                                            Headquarters
                                          901 N. Glebe Road                                 Jose Pablo Arronte
                                                                                              Junior Analyst
                                               5th Floor                              jarronte@sealeassociates.com
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                                                                                            Regina Labardini
                                          +1 (703) 294 6770                                   Junior Analyst
                                                                                     rlabardini@sealeassociates.com

  Please contact us if you would like further information about M&A trends and/or
                   specific transaction multiples for your industry

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