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JOINT EVENT 7th World Congress on Addictive Disorders & Addiction Therapy & 29th International Conference on Sleep Disorders and Psychiatry July 16-18, 2018 London, UK Scientific Tracks & Abstracts Day 1 Addiction Congress 2018 & Sleep Congress 2018 Page 19
Sessions Day 1 July 16, 2018 Sleep Disorders | Neural Control And Neurologics Sleep Disorder | Addiction & Mental Health | Addiction & Behavioral Studies Session Chair Session Chair Mark A K Patterson Lisa Turner Carilion Children’s Clinic, USA Newzealand Session Introduction Title: The effects of untreated sleep disorders in traumatic brain injury and its impact on executive function Melissa Mansukhani, Joe DiMaggio Children’s Hospital, USA Title: Blood miRNA profiles in the Korean individuals with internet gaming disorder Yeun-Jun Chung, The Catholic University of Korea, Republic of Korea Title: Conflict within: The epigenetics of troubled sleep William M Brown, University of Bedfordshire , UK Title: Sleep disorders based on its neurobiology of cognitive sciences and aromatherapy in compare with traditional Iranian-Islamic and Chinese medicines by classical or Hahnemann’s homeopathic medicine in neural control – A review research Abdolrasoul Aleezaadeh, Payame Noor University and University of Applied Science and Technology, Iran Title: Sleep disorder and neuro sensitivity Ravi Shankar Singh, Foundation of Mind Awakening and Neuro Analytical Studies – MAANAS, India Page 20
JOINT EVENT Melissa Mansukhani, Clin Psychiatry 2018, Volume 4 DOI: 10.21767/2471-9854-C1-002 7th World Congress on Addictive Disorders & Addiction Therapy & 29th International Conference on Sleep Disorders and Psychiatry July 16-18, 2018 London, UK The effects of untreated sleep disorders in traumatic brain injury and its impact on executive function Melissa Mansukhani Joe DiMaggio Children’s Hospital, USA Statement of the Problem: Individuals who have sustained traumatic brain injury have a higher risk of suffering from sleep disorders. The most common of the sleep disorders is sleep apnea. Sleep apnea is defined as the cessation of breathing in conjunction with frequent arousals and hypoxemia. Researchers have found that untreated sleep apnea has been linked to cognitive decline and behavioral deficits. However, not much light has been shed on the effect of untreated sleep disorders in traumatic brain injury. The purpose of this analysis is to describe what the impact is on executive function when traumatic brain injury occurs and sleep apnea is not treated along with other more common treatments for this condition. Methodology & Theoretical Orientation: Review and evaluate published work related to sleep apnea. An ecological framework was utilized to focus on the interaction between the counselors and the staff to understand this relationship and the context in which it occurs. Findings: There continues to be a need for more research in the longitude effects of untreated sleep apnea in traumatic injury patients. When the brain is injured the normal pathways for executive function are disturbed. Hypotension and hypoxia both contribute to poor cognitive outcomes. Depending on the incidents duration and extent of tissue hypoxia it is linked to poor neuropsychological outcomes post traumatic brain injury. Many studies have concluded the relationship between sleep apnea and cognitive deficits, including executive function, attention/vigilance, language, memory and psychomotor speed. Authors also believe that untreated childhood obstructive sleep apnea could permanently alter a developing child’s cognitive potential. In more severe OSA cases the gold standard is still continuous positive airway pressure without oxygen. Another important connection is the relationship between sleep apnea executive dysfunction and post-TBI is comorbid psychopathology. Patient’s post-TBI has a risk of developing depression but with sleep apnea the risk is nearly twofold for major depression. Conclusion & Significance: Patients with post-TBI would benefit from proper sleep evaluation to determine what the right intervention is to effectively treat his/her overall condition. Untreated OSA or SA will result in decline in cognitive as well as executive functions. Gold standard of OSA treatment is CPAP without oxygen. Recommendations are made for proper treatment of post traumatic brain injury patients. Recent Publications 1. Langlois J A and Sattin R W (2005) Traumatic brain injury in the United States: Research programs of the centers for disease control prevention (CDC). J Head Trauma Rehabil 20(3):187-188. 2. Johnston A J, Steiner L A, Coles J P, Charfield D A, Fryer T D, et al. (2005) Effect of cerebral perfusion pressure augmentation on regional oxygenation and metabolism after head injury. Crit Care Med 33:189-195. 3. Rose J C, Neill T A and Hemphill J C 3rd (2006) Continuous monitoring of the microcirculation in neurocritical care: an update on brain tissue oxygenation. Curr Opin Crit Care 12:97-102. 4. Naismith S, Winter V, Gotsopoulos H, Hickie I and Cistulli P (2004) Neurobehavioral functioning in obstructive sleep apnea: differential effects of sleep quality, hypoxemia and subjective sleepiness. J Clin Exp Neuropsychol 26:43-54. 5. Valencia Flores M, Bliwise D, Guilleminault C, Cilveti R and Clerk A (1996) Cognitive function in patients with sleep apnea after acute nocturnal nasal continuous positive airway pressure (CPAP) treatment: sleepiness and hypoxemia effects. J Clin Exp Neuropsychol 18(2):197-210. Clinical Psychiatry Volume 4 ISSN: 2471-9854 Page 21
JOINT EVENT 7th World Congress on Addictive Disorders & Addiction Therapy & 29th International Conference on Sleep Disorders and Psychiatry July 16-18, 2018 London, UK Biography Melissa Mansukhani has her expertise in pediatric sleep evaluation. Her hard work and dedication to her patients and families have shaped the pediatric sleep center at Joe DiMaggio Children’s Hospital. Her 11 years of pediatric clinical sleep experience and 15 years of clinical and research helped shape pathways to improve healthcare and technological training for her staff. She has built this program, after years of experience teaching, evaluating and managing in hospital and research institutions. The Joe DiMaggio Children’s Hospital Sleep Center is a patient-family centered organization that diagnosis, evaluates and treats patients with pediatric sleep disorders. She is a member of the American Association of Sleep Technologists (AAST), where she sat on the Standards and Guidelines Committee, authored the pediatric split night protocol and contributed to other protocols. melissa.mansukhani@gmail.com Notes: Clinical Psychiatry Volume 4 ISSN: 2471-9854 Page 22
JOINT EVENT Yeun-Jun Chung et al., Clin Psychiatry 2018, Volume 4 DOI: 10.21767/2471-9854-C1-002 7th World Congress on Addictive Disorders & Addiction Therapy & 29th International Conference on Sleep Disorders and Psychiatry July 16-18, 2018 London, UK Blood miRNA profiles in the Korean individuals with internet gaming disorder Yeun-Jun Chung1, Minho Lee1, Hyeyoung Cho1, Seung Hyun Jung1, Seon-Hee Yim1, Sung-Min Cho1, Ji-Won Chun1, Soo-Hyun Paik2, Ji Eun Lee2, Jung- Seok Choi3 and Dai-Jin Kim1 1 The Catholic University of Korea, Republic of Korea 2 Korea Institute of Science and Technology, Republic of Korea 3 Boramae Medical Center, Seoul, Republic of Korea A ddictive use of Internet and Internet-based games is not just a social phenomenon in some countries with extensive Internet access infrastructure, but a potential psychiatric disorder termed Internet gaming disorder (IGD). According to the epidemiological reports, prevalence rates of IGD in adolescents vary across diverse countries ranging from 0.8% to 26.7%. Especially, studies showed above 10% of prevalence rates in adolescents in many Asian countries such as South Korea, China, Taiwan, Hong Kong and Singapore. IGD is known to be associated with impairment in cognition, psycho-social relationship and daily life such as reductions in academic or occupational performances. IGD is now included in Section III (Conditions for Further Study) of the fifth revision of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V). However, inspite of its clinico-social importance, little is known about the molecular genetic mechanism behind IGD. In this study, we aimed to identify IGD-associated miRNA markers by observing differentially expressed plasma miRNAs between the IGD and control groups and explored their biological implications. Biography Yeun-Jun Chung is a Professor of Medical Genomics at Catholic University of Korea, College of Medicine, Korea. Since he has completed his PhD in 1989, he has studied Genomics and Informatics. Now, he is a Director of Precision Medicine Research Center, Catholic Medical College. He has published more than 100 papers in reputed journals in diverse fields of medicine including cancer, complex disease, and neuropsychiatric disorders. yejun@catholic.ac.kr Notes: Clinical Psychiatry Volume 4 ISSN: 2471-9854 Page 23
JOINT EVENT William M Brown, Clin Psychiatry 2018, Volume 4 DOI: 10.21767/2471-9854-C1-002 7th World Congress on Addictive Disorders & Addiction Therapy & 29th International Conference on Sleep Disorders and Psychiatry July 16-18, 2018 London, UK Conflict within: The epigenetics of troubled sleep William M Brown University of Bedfordshire, UK Statement of the Problem: Genomic imprinting — parent-of-origin dependent gene expression evolves at a locus when there is a conflict of interest between parental genomes within offspring over the optimal level of maternal investment. Conflicts emerge due to relatedness asymmetries within families (e.g., caused by multiple paternity and sex-biased dispersal). Here it is argued based on Haig (2014) and McNamara (2014) -- that sleep disturbance is caused by underlying genetic conflicts over the optimal amount of maternal investment. The purpose of this study is to outline the neurobiological and behavioral evidence that imprinted genes and intragenomic conflicts cause sleep disturbance. Furthermore, I outline the possibility of how intragenomic conflict resolution may occur to reduce sleep disturbances. Methodology & Theoretical Orientation: Three studies are discussed from evolutionary and attachment theoretical perspectives. Study one outlines the case for imprinted gene involvement in sleep regulation. Study two and three investigate the degree to which poor attachment style is a positive correlate of nightmare occurrence. Findings: As expected, study one shows that the frequency of imprinted genes involved in sleep regulation is greater than chance (i.e., considering imprinted genes are rare). Studies two and three reveal that young adults with insecure attachment styles self-report more nightmares. Conclusion & Significance: Preliminary evidence is consistent with an intragenomic conflict perspective and previous work on sleep regulation. It is expected that paternal genes increase offspring sleep disturbance, whilst maternal genes minimize night waking. Future work should explore whether self-reports of disturbed sleep are valid (e.g., behavioral sleep lab work) and parent-of-origin gene network activation whilst sleeping. It is important to note that intragenomic conflict resolution may be mediated by secure attachment style providing a potential pathway for treatment of sleep disturbance. Recent Publications 1. Brown W M (2015) Exercise-associated DNA methylation change in skeletal muscle and the importance of imprinted genes: A bioinformatics meta-analysis. British Journal of Sports Medicine 49(24):1567-1578. 2. Haig D (2014) Troubled sleep: Night waking, breastfeeding and parent-off spring conflict. Evolution, Medicine and Public Health 1:32-39. 3. Hanna C W and Kelsey G (2017) Genomic imprinting beyond DNA methylation: A role for maternal histones. Genome Biology 18:177. 4. Mcnamara P (2014) Comment on David Haig’s troubled sleep: Implications for functions of infant sleep. Evolution, Medicine and Public Health 1:54-56. 5. Tucci V (2016) Genomic imprinting: A new epigenetic perspective of sleep regulation. PLOS Genetics 12(5):e1006004. Biography William M Brown was a Natural Science and Engineering Research Council (NSERC) and Killam Scholar whilst completing a PhD at Dalhousie University, Canada. Subsequently, he received a NSERC Postdoctoral Fellowship to study Genomic Imprinting in the USA. In 2006, he founded the Centre for Culture and Evolutionary Psychology at Brunel University teaching evolutionary biology and research methods. In 2009, he moved to Queen Mary, University of London and University of East London to teach research methods and behavioral biology. He has been at the University of Bedfordshire since 2011 and was appointed Senior Lecturer in the School of Psychology in 2015. His interests reside in the evolution of cooperation, development and genomic imprinting. The three topics merge in his work on sleep disturbance, which suggests that frequent night waking mediated by paternal genes was designed to extract social resources from mothers. Cooperation between parental genomes may facilitate more restful sleep and secure attachment between mother and child. william.brown@beds.ac.uk Clinical Psychiatry Volume 4 ISSN: 2471-9854 Page 24
JOINT EVENT Abdolrasoul Aleezaadeh, Clin Psychiatry 2018, Volume 4 DOI: 10.21767/2471-9854-C1-002 7th World Congress on Addictive Disorders & Addiction Therapy & 29th International Conference on Sleep Disorders and Psychiatry July 16-18, 2018 London, UK Sleep disorders based on its neurobiology of cognitive sciences and aromatherapy in compare with traditional Iranian-Islamic and Chinese medicines by classical or Hahnemann’s homeopathic medicine in neural control – A review research Abdolrasoul Aleezaadeh Payame Noor University and University of Applied Science and Technology, Iran Statement of the Problem: Since the Sleep Disorders treatment is difficult by the chemical routine drugs; then, therapist must be thought beyond these routine treatments. Choosing Aromatherapy by some Plants considering with innate humor or, temperament of the same plants and, matching of these by patients’ innate humors or, temperaments based on Traditional Islamic-Iranian and, Chinese Medicines with combination of Hahnemann’s Classical Homeopathic Medicine Rubrics, can extract inner Miasma of the sleep disorder pathology of patients and, recover and, cure them in the best way of Neurobiological base of Cognitive Science – in the cellular base of neural control. Orientation: The method used in this research is a library analysis; therefore, after collecting information and data from the sources, using the library method, according to the subject and the problem of the present study, after the critique, the data, have been analyzed in order to explain the research problem. Findings: As sleeping is a powerful energetic compensatory behavior in creatures’ circadian living cycle – even in cold-blooded creatures, that they sleeping almost in cold season for a long time in the year, in compare with hot-blooded creatures, especially human being – and, although almost all creatures have major common points in their neurobiological themes level; but, the human being, among other creatures has his/her specifications in this theme level; why, he/she has wise, thinking, and such abilities that these separate him/her from other creatures. Thinking, as a power of wise of human, in combination with Action Potential Simulation Therapy/A.P.S.T and, odors, considering the type of food and, feeding and, based on the base humor/ temperament and, main innate miasma, affects his/her neural biology – as its secretions, neurotransmitters and, in additions, neural intracellular interactions in cellular basis – and, in psychological cognitive science basis, attitudes and, mind cognitive space; and, follow of this, sleeping has influence by these determinants. The conclusion of these cases, in reductionism base, have establish a neural control that it due to homeostasis or, balancing or, not – it means, Sleep Disorders/S.Ds. Of course, sleeping isn’t excluded of these counted cases. Biography Abdolrasoul Aleezaadeh completed his Post–Doctorate in Psychology from USA. He completed his master’s Degree in Clinical Psychology and bachelor’s Degree in General Psychology from Iran. He is full expert international faculty professorship member in the Brooklyn Central University, USA. Associate expert international faculty professorship member in the Pacific Albion University, USA & Associate expert international faculty professorship member in the Green Lake (GreenLake) University, USA. abdolrasoul_alizadeh@yahoo.com Notes: Clinical Psychiatry Volume 4 ISSN: 2471-9854 Page 25
JOINT EVENT Ravi Shankar Singh, Clin Psychiatry 2018, Volume 4 DOI: 10.21767/2471-9854-C1-002 7th World Congress on Addictive Disorders & Addiction Therapy & 29th International Conference on Sleep Disorders and Psychiatry July 16-18, 2018 London, UK Sleep disorder and neuro sensitivity Ravi Shankar Singh Foundation of Mind Awakening and Neuro Analytical Studies – MAANAS, India Statement of the Problem: Every type and stage of sleep disorder can be eradicated easily and effectively by altering the neuro sensitivity of concerned brain in the required direction. Every brain suffering from any type and stage of sleep disorder is suffering primarily with the loss of its harmony (homeostasis) followed by altered secretion of necessary fluid, chemical and electrical activity resulting in alteration of neuro sensitivity of the concerned brain. Purpose of the Study: Sleep disorders are becoming global epidemic and serious enough to interface with normal physical, mental, social and emotional functioning. Methodology & Theoretical Orientation: Every brain is programmed differently than that of another. Some brain is more prone to receive and retain stress from surroundings then that of another. In order to understand the cause of any functional neurological disorder we have to understand the programming of that concerned brain which decides it’s: thinking pattern, behaving pattern, feeling pattern, responding pattern, etc. Human brain is an ultimate creation of nature. In order to understand the programming of the concerned brain we need to know the language of nature being illustrated clearly in different form, on the body of that concerned brain. Sleep is a natural mental process in which the secretion of required fluid and all activity becomes optimum when brain is in harmony. Every brain has a critical limit towards a thrust and it is also different for different brain. Findings: Study was carried out on 673 brains suffering from different types of sleep disorders of different age groups about 69 percent (465) brain responded with sound sleep and 26 percent (175) with moderate benefit and 4 percent (27) with slight benefit (by revert signaling therapy). Conclusion & Significance: Further study and analysis is required on more scientific axes in advanced laboratory. Biography Ravi Shankar Singh has expertise in understanding mental engineering and neurological interactions and their complex functions including neurological programming. He is also engaged in finding some unconventional means of healing and relieving human being suffering from functional mental ailments by reviving and modifying ancient Indian methodologies. He is currently working at Foundation of Mind Awakening and Neuro Analytical Studies. ravissingh388@gmail.com Notes: Clinical Psychiatry Volume 4 ISSN: 2471-9854 Page 26
JOINT EVENT 7th World Congress on Addictive Disorders & Addiction Therapy & 29th International Conference on Sleep Disorders and Psychiatry July 16-18, 2018 London, UK Workshop Day 2 Addiction Congress 2018 & Sleep Congress 2018 Page 33
JOINT EVENT Dave Singh, Clin Psychiatry 2018, Volume 4 DOI: 10.21767/2471-9854-C1-002 7th World Congress on Addictive Disorders & Addiction Therapy & 29th International Conference on Sleep Disorders and Psychiatry July 16-18, 2018 London, UK Dave Singh Vivos BioTechnologies, Inc., USA Pneumopedics: Non-surgical upper airway remodeling for pediatric obstructive sleep apnea C urrently, the management of pediatric obstructive sleep apnea (OSA) remains undecided. Often, the tonsils and adenoids are surgically removed but this intervention does not always produce the desired outcome, and alternatives must be sought. On the other hand, continuous positive airway pressure (CPAP) is often contra-indicated in pediatric OSA, unlike adult OSA. However, mandibular advancement devices (MADs) are often used as alternatives to CPAP in adult OSA. Therefore, alternative solutions to pediatric OSA are also required. Biomimetics is a science that studies natural models and uses these designs and processes to solve human health issues. For example, in modern humans (Homo sapiens sapiens), the natural design includes 32 teeth, which are symmetrically-arranged within the human craniofacial architecture. This structural pattern is achieved through developmental processes (e.g. temporo-spatial patterning) that are encoded within the human genome, including growth and development of the mandible and eruption of the teeth. Studies have shown that the growth and development of the mandible can be modified in 2D and 3D studies. In fact, monozygotic twins respond to removable appliances that reposition the mandible during growth favorably. However, not all pediatric devices are effective in mandibular repositioning during growth, and careful selection is mandatory. In responsive cases, however, both pre-formed and customized devices are cost effective. In fact, significant changes in upper airway morphology have been induced in children using these techniques. It is concluded that this pneumopedic approach may be considered for non-surgical upper airway remodeling in pediatric cases of obstructive sleep apnea. Recent Publications 1. Singh G D and Clark W J (2001) Localization of mandibular changes in patients with class II division 1 malocclusions treated using twin block appliances: Finite-element modeling. American Journal of Orthodontics and Dentofacial Orthopedics 119(4):419-425. 2. Elfeky H Y, Fayed M S, Alhammadi M S, Soliman S A Z and El Boghdadi D M (2018) Three-dimensional skeletal, dentoalveolar and temporomandibular joint changes produced by twin block functional appliance. Journal of Orofacial Orthopedics DOI: 10.1007/s00056-018-0137-1. 3. Condò R, Perugia C, Bartolino M and Docimo R (2010) Analysis of clinical efficacy of interceptive treatment of class II division 2 malocclusion in a pair of twins through the use of two modified removable appliances. Journal of Oral Implantology 3(3):11-25. 4. Pavoni C, Cretella Lombardo E, Lione R, Bollero P, Ottaviani F and Cozza P (2017) Orthopaedic treatment effects of functional therapy on the sagittal pharyngeal dimensions in subjects with sleep-disordered breathing and class II malocclusion. Acta Otorhinolaryngologica Italica 37(6):479-485. 5. Cozza P, Polimeni A and Ballanti F (2004) A modified monobloc for the treatment of obstructive sleep apnoea in paediatric patients. European Journal of Orthodontics 26:523-530. Clinical Psychiatry Volume 4 ISSN: 2471-9854 Page 34
JOINT EVENT 7th World Congress on Addictive Disorders & Addiction Therapy & 29th International Conference on Sleep Disorders and Psychiatry July 16-18, 2018 London, UK Biography G D Singh holds three doctorates, including Doctor of Dental Medicine; a PhD in Craniofacial Development, and a DDSc in Orthodontics. He was invited to relocate to the Center for Craniofacial Disorders, USA where he led a NIH-funded program of craniofacial/cleft lip and palate research. Currently, he is a Board Member of the American Sleep and Breathing Association, a member of the World Sleep Federation, an Academic Fellow of the World Federation of Orthodontists, and Fellow of the International Association for Orthodontics, where he was awarded prizes in 2005, 2013 and 2014. He has published over 200 articles and books in the peer-reviewed medical, dental and orthodontic literature, and has lectured in Australia, Asia, Europe, Africa and North America. Currently, he is President of Vivos BioTechnologies, Inc. drsingh@drdavesingh.com Notes: Clinical Psychiatry Volume 4 ISSN: 2471-9854 Page 35
JOINT EVENT Mark A K Patterson, Clin Psychiatry 2018, Volume 4 DOI: 10.21767/2471-9854-C1-002 7th World Congress on Addictive Disorders & Addiction Therapy & 29th International Conference on Sleep Disorders and Psychiatry July 16-18, 2018 London, UK Mark A K Patterson Carilion Children’s Clinic, USA Practical approaches to paediatric sleep disorders Statement of the Problem: After over a century of study, the exact function of sleep remains elusive. Despite this uncertainty, the value of adequate sleep is undeniable. This value is especially critical in a population who spend almost half of their lives asleep, during the important developmental years: children. Sleep disorders in the paediatric population are often the result of a complex interplay between numerous factors, including medical, interpersonal, and societal. Children do not often complain about sleep problems; a medical evaluation is commonly initiated by an adult caregiver whose own sleep is being impacted. In evaluating a child with a sleep problem it is critical that the clinician to be able to determine what is the sleep problem, whose problem it is, and what is the etiology of the problem. The ability of the clinician to effectively communicate their findings and recommendations to the family is also essential. Format: This presentation will provide the attendees with an overview of common paediatric sleep disorders, including insomnias, hypersomnias, and parasomnias. Case presentations will then be discussed, allowing for an open forum between the leader and participants. The discussion will focus on current recommendations for evaluation and treatment, strategies to improve clinician-parent communications, and address needs of those participating to enable them to optimize the care they provide to their patients. Conclusions & Significance: This workshop should provide the clinician with the tools necessary to better understand common paediatric sleep disorders, how to differentiate between various etiologies, and how to work effectively with families to develop treatment strategies. Recent Publications 1. Villa K F, Black J, Bujanover S, Cisternas M G, Gow M, Ohayon M M, Pasta D J, Patterson M and Thorpy M J (2017) Assessing the benefits of sodium oxybate (SXB) on functioning, productivity, and health-related quality of life in people with narcolepsy: findings from the nexus narcolepsy registry. Sleep 40(1):A241. 2. Pasta D J, Black J, Bujanover S, Cisternas M G, Gow M, Ohayon M M, Patterson M, Thorpy M J and Villa K F (2017) Factors associated with narcolepsy medication treatments and medication discontinuation rates: findings from the nexus narcolepsy registry. American Academy of Sleep Medicine 40(1):A250. Biography Mark A K Patterson has his interest in narcolepsy and cataplexy crystalized, when a close family member was diagnosed with the condition in 2004. Since that time, he has been active in raising awareness about the condition to his medical colleagues and general public and currently serves as the President of Narcolepsy Network. He practices as a General Pediatrician with the Carilion Clinic in Roanoke, Virginia, USA. He received his medical training from Albany (New York) Medical College with spe- cialty education from the University of Virginia, Charlottesville. Prior to his medical career, he received a PhD in Biological Chemistry from the Massachusetts Institute of Technology, Cambridge and worked in the fledgling biotechnology industry. mpatterson@narolepsynetwork.org Clinical Psychiatry Volume 4 ISSN: 2471-9854 Page 36
JOINT EVENT Andrew Matthews, Clin Psychiatry 2018, Volume 4 DOI: 10.21767/2471-9854-C1-002 7th World Congress on Addictive Disorders & Addiction Therapy & 29th International Conference on Sleep Disorders and Psychiatry July 16-18, 2018 London, UK Andrew Matthews State University of New York Orange, USA Moments…An evening with Bill W T he purpose of this paper and presentation is to offer treatment providers and practitioners insight into the development of 12 step programs and their value as a viable option in conjunction with traditional treatment methods for all levels of care including aftercare. Alcoholics Anonymous (AA) is a self-help group organized through an international organization of recovering alcoholics that offers emotional support and a model of abstinence for people recovering from alcohol dependence using a 12-step approach (Cochrane Library). AA and other 12 step approaches are typically based on the assumption that substance dependence is a spiritual and medical disease. Simply, directing a client to attend AA once a week is not enough. Bill Wilson and Co-founder Dr. Bob Smith, began the practice of telling their drinking stories to other alcoholics early in 1935. Later known as 12 step work, this required each member to carry the message of sobriety to another suffering alcoholic as part of their inherent duty to stay sober. Evidence indicates that 12 step mutual help organizations such as AA can play an important role in extending and potentiating the recovery benefits of professionally delivered addiction treatment among young adults with substance abuse disorders. Dr. Bob provided detoxification services at the Akron City Hospital for almost 15 years from 1935 till his death in 1950 all the while sponsoring over 5000 patients who would later become AA members. Like the professional clinical realm, the therapeutic alliance among sponsees and their sponsors predicts better substance abuse outcomes. Youth treatment programs frequently employ 12 step concepts and encourage participation in AA. Since AA groups are easily accessible at no charge and provide flexible support at times of high risk relapse they hold promise as a treatment adjunct in an increasingly cost constructing economic climate. The main objective of this presentation is for participants to understand the beginnings of the Alcoholics Anonymous 12 step program through the theatrical illustration of Bill Wilson’s alcoholism and recovery from the early 1920’s right up to 1950. Furthermore, participants would understand how 12 step programs are the forefathers of the treatment programs we know today while much more advanced now what still holds true is the essence of treatment which is one person reaching out and helping another. In addition, participants will become familiar with one person’s struggle with alcoholism, how they came to find recovery and how they could successfully pass it on to others which still holds true over 80 years later. Biography Andrew Matthews completed his Bachelor’s Degree in Theater Arts at State University of New York at both Orange County and New Paltz campuses. In addition, he continues to train at HB Studios and Actors Connection in New York. He has worked in the substance abuse field since 1990 at all levels of treatment including inpatient, outpatient, detox and residential services where he worked as Counselor, Supervisor and Trainer. He currently works for the New York State Office of Alcoholism and Substance Abuse in the Quality Services and Practice Improvement Division and has contact with over 50 programs annually in the New York. In addition, he sits in the Academy of Addiction Studies at the New York State Office of Alcoholism and Substance Abuse and has also studied Social Work at Fordham University. momentsbillw@gmail.com Notes: Clinical Psychiatry Volume 4 ISSN: 2471-9854 Page 37
JOINT EVENT 7th World Congress on Addictive Disorders & Addiction Therapy & 29th International Conference on Sleep Disorders and Psychiatry July 16-18, 2018 London, UK Scientific Tracks & Abstracts Day 2 Addiction Congress 2018 & Sleep Congress 2018 Page 39
Sessions Day 2 July 17, 2018 Sleep Disorders | Addiction Rehabilitation & Recovery Session Chair Session Chair Ancy John Mark A K Patterson Graylands Hospital, Australia Carilion Children’s Clinic, USA Session Introduction Title: Predictors of actigraphy - derived sleep measures in a community sample Shireen W Eid, Australian National University, Australia Title: Rehabilitation model in the field of addiction in Turkey: Yeşilay Consultancy Center (YEDAM) Hakan Karaman, Istanbul University, Turkey Title: Sleep disorders in epilepsy Anna Voitiuk, Kharkiv Medical Academy of Postgraduate Education, Ukraine Page 40
JOINT EVENT Shireen W Eid et al., Clin Psychiatry 2018, Volume 4 DOI: 10.21767/2471-9854-C1-002 7th World Congress on Addictive Disorders & Addiction Therapy & 29th International Conference on Sleep Disorders and Psychiatry July 16-18, 2018 London, UK Predictors of actigraphy - derived sleep measures in a community sample Shireen W Eid and Rhonda F Brown Australian National University, Australia Statement of the Problem: Many factors are reported to interfere with sleep in otherwise healthy adults. However, most relevant studies were only cross-sectional in nature or they tested only a small number of risk factors. Fewer of them have examined a large pool of potential predictors in a longitudinal study to determine which can most strongly predict impaired sleep. Thus, we examined demographics, symptoms/disorders, physical activity, other behavior (e.g. substance use, electronic device use) and work-contexts as predictors of sleep quality at T1 (cross-sectional) and 3-months later (T2, longitudinal), in a community sample. Methodology & Theoretical Orientation: The sample included 161 participants aged 18–65 years. They completed questionnaires at T1 and T2 that asked about demographics and their recent experiences of sleep, night-eating, affective distress (i.e., stress, anxiety, depression), physical activity, substance use (e.g., caffeine, alcohol, drugs), work-context (i.e. shift-work) and parenting young children. Their physical activity and sleep were monitored via actigraphy for 24-hours at T1 and T2. Findings: Hierarchical multiple regression analysis examined the factors as predictors of sleep quality at T1 and T2. At T2, longer sleep onset latency was predicted by parenting young children and watching TV at night; shorter sleep duration was predicted by female gender; and more awake time and less sleep efficiency were predicted by less alcohol intake. In contrast, all of the T1 sleep measures were predicted by physical activity, including total number of steps, METs and time spent travelling, with the exception of awake time, which was predicted also by less education. Conclusion & Significance: A combination of demographics (e.g. female gender, less education), consumption behavior (i.e. alcohol intake) and other behavior (i.e. watching TV at night, parenting young children) may contribute to poor sleep quality in the short-term and longer-term. Recent Publications 1. Kredlow M A, Capozzoli M C, Hearon B A, Calkins A W and Otto M W (2015) The effects of physical activity on sleep: a meta-analytic review. Journal of Behavioral Medicine 38(3):427-449. 2. Fossum I N, Nordnes L T, Storemark S S, Bjorvatn B and Pallesen S (2014) The association between use of electronic media in bed before going to sleep and insomnia symptoms, daytime sleepiness, morningness, and chronotype. Behavioral Sleep Medicine 12(5):343-357. 3. Li R, Wing Y, Ho S and Fong S (2002) Gender differences in insomnia - A study in the Hong Kong Chinese population. Journal of Psychosomatic Research 53(1):601-609. 4. Thompson J F, Roberts C L, Currie M and Ellwood D A (2002) Prevalence and persistence of health problems after childbirth: associations with parity and method of birth. Birth 29(2):83-94. Biography Shireen W Eid is a PhD student at the Psychology Department in the ANU. She has a Master’s degree in Human Physiology from Jordan University of Science and Technology (JUST). She did her Bachelor’s in Physiotherapy from the University of Jordan. She has experience in conducting research studies in humans as part of her post-graduate degrees. Shireen.Eid@ANU.edu.au Clinical Psychiatry Volume 4 ISSN: 2471-9854 Page 41
JOINT EVENT Hakan Karaman et al., Clin Psychiatry 2018, Volume 4 DOI: 10.21767/2471-9854-C1-002 7th World Congress on Addictive Disorders & Addiction Therapy & 29th International Conference on Sleep Disorders and Psychiatry July 16-18, 2018 London, UK Rehabilitation model in the field of addiction in Turkey: Yeşilay Consultancy Center (YEDAM) Hakan Karaman and Ömer Miraç Yaman İstanbul University, Turkey T his study was planned to develop a basic critique of Yeşilay Consultancy Center (YEDAM), which is working in the field of addiction treatment and rehabilitation in Turkey. In this study, which was prepared as a case study from qualitative study methods, in-depth interviews, participant observation and document analysis were used from data collection techniques. In this sense, YEDAM model was examined from the administrative and institutional structure of the model up to the professional intervention stage; the collected data were interpreted thematically and proposals for the development of the model at the end of the study were presented. Strong institutional structure, constantly supervision support, client-oriented multidisciplinary approach and community-based treatment approach were founded as important aspects of the YEDAM model in the study. Besides, including the professional social work intervention in the treatment of addiction and using experiences of ex-users highlight the model among other examples in Turkey. Because of this features, YEDAM may be developed as pioneering addiction rehabilitation model in Turkey. On the other hand, there are disadvantages for the model such as lack of qualified staff in the field, lack of cooperation among institutions and lack of medical treatment support. When considered from academic point of view, this is the first study of YEDAM in the literature. In terms of content, it is also important to prioritize contributing to the development of YEDAM by including critics and suggestions. Biography Hakan Karaman has completed his undergraduate studies in Social Work Department at Yalova University in 2015; and Graduation in Social Work Department at İstanbul University in 2017. He is a Research Assistant in Social Work Department at İstanbul University. He has published three review papers and a book. karamannhakann@gmail.com Notes: Clinical Psychiatry Volume 4 ISSN: 2471-9854 Page 42
JOINT EVENT Anna Voitiuk et al., Clin Psychiatry 2018, Volume 4 DOI: 10.21767/2471-9854-C1-002 7th World Congress on Addictive Disorders & Addiction Therapy & 29th International Conference on Sleep Disorders and Psychiatry July 16-18, 2018 London, UK Sleep disorders in epilepsy Anna Voitiuk and T Litovchenko Kharkiv Medical Academy of Postgraduate Education, Ukraine Introduction: Epilepsy is closely connected with the sleep-wake cycle: the disease often causes sleep disorder and its structure and this, in turn, worsens epilepsy. Sleep disorders often provoke the appearance of various paroxysmal conditions, which are then difficult to differentiate from epileptic phenomena. The objective of this study is to determine the nature of paroxysmal disorders occurring during sleep, and study the impact of antiepileptic drugs (AEDs) on sleep architecture. Methods: Studies were conducted on the basis of the analysis of clinical symptoms and instrumental studies. EEG, EEG-video monitoring and polysomnography were used as screening methods. Results: Data analysis of 300 patients aged 18-55 revealed the presence of epileptiform (25%) and non-epileptiform phenomena (28%), among which there were present parasomnias (somnambulism, nightmares, bruxism) – 5% and dyssomnias (difficulty falling asleep, frequent nocturnal awakenings, hypersomnia) – 23%. 10% of patients had a combination of both non-epileptiform and epileptiform phenomena, which greatly hampered the diagnosis. Fifteen patients (5%) didn’t have any sleep disorders. In the study of 137 patients with epilepsy during an inter-paroxysmal period, EEG showed certain increase in the number of "sleep spindles" and their high synchronization (amplitude, duration) in comparison with 163 patients with wakeful epilepsy. The influence of AEDs on sleep structure cannot be excluded either. In patients receiving carbamazepine (7%), the REM-sleep phase decreased, especially at the beginning of treatment. In patients treated with valproate (5%), the 1st stage of sleep increased while the clinical course of obstructive sleep apnea worsened as a result of side effects. In patients taking lamotrigine (3%), the slow-wave sleep stage decreased, while in patients treated with levetiracetam (8%), sleep continuity improved and there was some increase in the slow-wave stage. Conclusion: The study revealed that sleep disorders in patients with epilepsy are observed in 53% of cases. AEP affects the structure and quality of sleep. The differential diagnosis of epileptic and non-epileptic sleep disorders has a lot of problems in clinical practice. Adequate assessment of the syndrome is essential for developing optimal treatment strategies. Recent Publications 1. Khachatryan S G (2017) An effect of epilepsy on sleep structure. Journal of Neurology and Psychiatry Im S S Korsakova 117:88-94. 2. Roohi Aziz M (2017) Changes of the brain’s bioelectrical activity in cognition, consciousness, and some mental disorders. Medical Journal of the Islamic Republic of Iran 31:53. 3. Mekky J F (2017) Sleep architecture in patients with juvenile myoclonic epilepsy. Sleep Medicine 38:116-121. 4. Foldvary-Schaefer N R (2017) Sleep-disordered breathing. Continuum: Lifelong Learning in Neurology 23:1093-1116. 5. Staniszewska A (2017) Sleep disturbances among patients with epilepsy. Neuropsychiatric Disease and Treatment 13:1797-1803. Biography A Voitiuk has graduated from Kharkiv National Medical University in 2013 with major in General Medicine. From 2013 till 2015 she studied as a Postgraduate student in Neurology at Kharkiv Medical Academy of Post-Graduate Education. During her residency she has shown interest and enthusiasm in treating patients with disorder of cerebral circulation, epilepsy and spinal diseases. She studied at the EAN Spring School and got a certificate about finishing in 2017. Currently she is a qualified Neurologist. She is an active participant in case report discussions and always ready to suggest original solutions. She takes active part in scientific conferences and has scientific publication. a_vojtyuk@yahoo.com Clinical Psychiatry Volume 4 ISSN: 2471-9854 Page 43
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