SCHWERPUNKT: Kinderwunsch und Reproduktionsmedizin
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SCHWERPUNKT: Kinderwunsch und Reproduktionsmedizin
Folsäure, Kinderwunsch und Schwangerschaft (S. 7 – 10)
B. Lawrenz, A. Rißmann, B. Koletzko
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Zugegriffen: 27.06.2020
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http://www.ffinetwork.org/ country_profiles/index.php. Zugegriffen: 27.6.2020
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22. Bundesamt für Risikobewertung (BfR): Nutzen-Risiko-Bewertung einer
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23. Eryilmaz H, et al. Association of Prenatal Exposure to Population-Wide Folic Acid
Fortification with Altered Cerebral Cortex Maturation in Youths. JAMA Psychiatry
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25. Ebbing M et al. Cancer incidence and mortality after treatment with folic acid and
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27. Qi YP et al. The prevalence of low serum vitamin B‐12 status in the absence of
anemia or macrocytosis did not increase among older U. S. adults after mandatory
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Vorbereitung auf eine Schwangerschaft und ein gesundes Baby – Wie Ernährung
und Nahrungsergänzungen dabei helfen (S. 12 – 18)
I. Gerhard
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80(4): 299–310
2. Gerhard I et al. Heavy metals and fertility. J Toxicol Environ Health A 1998; 54(8):
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and fertility disorders]. Zentralbl Gynakol 1992; 114(12): 593–602
4. Al-Saleh I et al. Exposure to phthalates in couples undergoing in vitro fertilization
treatment and its association with oxidative stress and DNA damage. Environ Res
2019; 169: 396–408
5. Philips EM et al. First Trimester Urinary Bisphenol and Phthalate Concentrations and
Time to Pregnancy: A Population-Based Cohort Analysis. J Clin Endocrinol Metab
2018; 103(9): 3540–3547
6. Mínguez-Alarcón L et al. Urinary concentrations of bisphenol A, parabens and
phthalate metabolite mixtures in relation to reproductive success among women
undergoing in vitro fertilization. Environ Int 2019; 126: 355–3627. Gerhard I. Das Frauen-Gesundheitsbuch: Wo Naturheilverfahren wirken, wann
Schulmedizin nötig ist. 2nd ed. 2014; München: Trias bei Thieme: 352
8. Andreas E et al. The effect of maternal high-fat/high-sugar diet on offspring oocytes
and early embryo development. Mol Hum Reprod 2019; 25(11): 717–728
9. Hollmann MB et al. Effects of weight loss on the hormonal profile in obese, infertile
women. Hum. Reprod 1996; 11(9): 1884–1891
10. Salas-Huetos A et al. Diet and sperm quality: Nutrients, foods and dietary patterns.
Reprod Biol 2019; 19(3): 219–224
11. Gerhard I et al. Myome selbst heilen. 2018, D-82418 Murnau a. Staffelsee: Mankau
Verlag: 175
12. Agarwal A et al. Male Oxidative Stress Infertility (MOSI): Proposed Terminology and
Clinical Practice Guidelines for Management of Idiopathic Male Infertility. World J
Mens Health 2019; 37(3): 296–312
13. Otasevic V et al. Evaluation of the antioxidative enzymes in the seminal plasma of
infertile men: Contribution to classic semen quality analysis. Syst Biol Reprod Med
2019; 65(5): 343–349
14. Nenkova GL et al. Role of Trace Elements for Oxidative Status and Quality of
Human Sperm. Balkan Med J 2017; 34(4): 343–348
15. Nadjarzadeh A et al. Effect of Coenzyme Q10 supplementation on antioxidant
enzymes activity and oxidative stress of seminal plasma: a double-blind randomised
clinical trial. Andrologia 2014; 46(2): 177–83
16. ElSheikh MG et al. Combination of vitamin E and clomiphene citrate in treating
patients with idiopathic oligoasthenozoospermia: A prospective, randomized trial.
Andrology 2015; 3(5): 864–7
17. Akhavizadegan H & Karbakhsh M, Comparison of serum vitamin D between fertile
and infertile men in a vitamin D deficient endemic area: a case-control study.
Urologia 2017; 84(4): 218–220
18. Abbasihormozi S et al. Association of vitamin D status with semen quality and
reproductive hormones in Iranian subfertile men. Andrology 2017; 5(1): 113–118
19. Nandi A et al. Is there a role for vitamin D in human reproduction? Horm Mol Biol Clin
Investig 2016; 25(1): 15–28
20. Montanino Oliva M et al. Effect of Myoinositol and Antioxidants on Sperm Quality in
Men with Metabolic Syndrome. Int J Endocrinol 2016; 1674950
21. Calogero AE et al. Myoinositol improves sperm parameters and serum reproductive
hormones in patients with idiopathic infertility: a prospective double-blind randomized
placebo-controlled study. Andrology 2015; 3(3): 491–5
22. Irani M et al. The Effect of Folate and Folate Plus Zinc Supplementation on
Endocrine Parameters and Sperm Characteristics in Sub-Fertile Men: A Systematic
Review and Meta-Analysis. Urol J 2017; 14(5): 4069–4078
23. Hosseini B et al. The Effect of Omega-3 Fatty Acids, EPA, and/or DHA on Male
Infertility: A Systematic Review and Meta-analysis. J Diet Suppl 2018; 1–12
24. Schisterman EF et al. Effect of Folic Acid and Zinc Supplementation in Men on
Semen Quality and Live Birth Among Couples Undergoing Infertility Treatment: A
Randomized Clinical Trial. Jama 2020; 323(1): 35–48
25. Magdi Y et al. Effect of modifiable lifestyle factors and antioxidant treatment on
semen parameters of men with severe oligoasthenoteratozoospermia. Andrologia
2017; 49(7)
26. Smits RM et al. Antioxidants for male subfertility. Cochrane Database Syst Rev
2019; 3(3): Cd00741127. La Vecchia I et al. Folate, homocysteine and selected vitamins and minerals status in
infertile women. Eur J Contracept Reprod Health Care 2017; 22(1): 70–75
28. Wilson RD et al. Pre-conception Folic Acid and Multivitamin Supplementation for the
Primary and Secondary Prevention of Neural Tube Defects and Other Folic Acid-
Sensitive Congenital Anomalies. J Obstet Gynaecol Can 2015; 37(6): 534–52
29. DeVilbiss EA et al. Preconception folate status and reproductive outcomes among a
prospective cohort of folate-replete women. Am J Obstet Gynecol 2019; 221(1):
51.e1–51.e10
30. Grajecki D et al. The effect of micronutrient supplements on female fertility: a
systematic review. Arch Gynecol Obstet 2012; 285(5): 1463–71
31. Amirjani S et al. Dietary intake and lifestyle behaviour in different phenotypes of
polycystic ovarian syndrome: a case-control study. J Hum Nutr Diet 2019; 32(4):
413–421
32. Butts SF et al. Vitamin D Deficiency Is Associated With Poor Ovarian Stimulation
Outcome in PCOS but Not Unexplained Infertility. J Clin Endocrinol Metab 2019;
104(2): 369–378
33. Zhao J et al. Vitamin D improves in-vitro fertilization outcomes in infertile women with
polycystic ovary syndrome and insulin resistance. Minerva Med 2019; 110(3): 199–
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34. Irani M et al. Vitamin D Decreases Serum VEGF Correlating with Clinical
Improvement in Vitamin D-Deficient Women with PCOS: A Randomized Placebo-
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35. Pal L et al. Vitamin D Status Relates to Reproductive Outcome in Women With
Polycystic Ovary Syndrome: Secondary Analysis of a Multicenter Randomized
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36. Akbari Sene A et al. The myo-inositol effect on the oocyte quality and fertilization rate
among women with polycystic ovary syndrome undergoing assisted reproductive
technology cycles: a randomized clinical trial. Arch Gynecol Obstet 2019; 299(6):
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37. Emekci Ozay O et al. Myo-inositol administration positively effects ovulation
induction and intrauterine insemination in patients with polycystic ovary syndrome: a
prospective, controlled, randomized trial. Gynecol Endocrinol 2017; 33(7): 524–528
38. Pacchiarotti A et al. Effect of myo-inositol and melatonin versus myo-inositol, in a
randomized controlled trial, for improving in vitro fertilization of patients with
polycystic ovarian syndrome. Gynecol Endocrinol 2016; 32(1): 69–73
39. Agrawal A et al. Comparison of metformin plus myoinositol vs metformin alone in
PCOS women undergoing ovulation induction cycles: randomized controlled trial.
Gynecol Endocrinol 2019; 35(6): 511–514
40. Mendoza N et al. Comparison of the effect of two combinations of myo-inositol and
D-chiro-inositol in women with polycystic ovary syndrome undergoing ICSI: a
randomized controlled trial. Gynecol Endocrinol 2019; 35(8): 695–700
41. Wojciechowska A et al. Inositols' Importance in the Improvement of the Endocrine-
Metabolic Profile in PCOS. Int J Mol Sci 2019; 20(22)
42. Advani K et al. Efficacy of combination therapy of inositols, antioxidants and vitamins
in obese and non-obese women with polycystic ovary syndrome: an observational
study. J Obstet Gynaecol 2020; 40(1): 96–101
43. Santanam N et al. Antioxidant supplementation reduces endometriosis-related pelvic
pain in humans. Transl Res 2013; 161(3): 189–9544. Yamamoto A et al. A prospective cohort study of meat and fish consumption and
endometriosis risk. Am J Obstet Gynecol 2018; 219(2): 178.e1–178.e10
45. Lu X et al. Effects of vitamin C on the outcome of in vitro fertilization-embryo transfer
in endometriosis: A randomized controlled study. J Int Med Res 2018; 46(11): 4624–
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Case-Control Study. Reprod Sci 2019; 26(2): 172–177
47. Espino J et al. Impact of Melatonin Supplementation in Women with Unexplained
Infertility Undergoing Fertility Treatment. Antioxidants (Basel) 2019; 8(9)
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systematic review of the literature. Reprod Biomed Online 2017; 35(6): 715–722
49. Budani MC & Tiboni GM, Effects of Supplementation with Natural Antioxidants on
Oocytes and Preimplantation Embryos. Antioxidants (Basel) 2020; 9(7)
50. Luddi A et al. Antioxidants reduce oxidative stress in follicular fluid of aged women
undergoing IVF. Reprod Biol Endocrinol 2016; 14(1): 57
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Zygote 2020: 1–15
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Neue Entwicklungen in der psychosozialen Kinderwunschberatung in Versorgung,
Forschung und Fortbildung (S. 27 – 31)
T. Wischmann, P. Thorn
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Keimzellen im Rahmen der assistierten Reproduktion. Dtsch Ärztebl 2018; 115(22):
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5. Thorn P. Aktuelle Bestandsaufnahme der psychosozialen Kinderwunschberatung in
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8. Michalsky D. Mit 58 schwanger! Na und? Stuttgart: LangenMüller; 2019
9. Micelli E et al. Desire for parenthood at the time of COVID-19 pandemic: an insight
into the Italian situation. J Psychosom Obst Gyn 2020: 1–8
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16. Mayer-Lewis B et al. Psychosoziale Kinderwunschberatung aus Sicht
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Kinderwunsch und Krebs – was ist zu beachten? (S. 32 – 34)
S. Findeklee
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techniques and therapeutic strategies in breast cancer, Hodgkin's lymphoma and
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4. Findeklee S et al. Fertility preservation in female cancer patients: current knowledge
and future perspectives. Minerva Ginecol 2019; 71(4): 298–305
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Reproduktionsmedizin in riskanter Sackgasse? (S. 35 – 41)
J. M. Wenderlein
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morbidity: a propensity score-matched cohort study. CMAJ 2019; 191(5): E118–
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Technologies With Arterial Hypertension During Adolescence. J Am Coll Cardiol
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lifetime risk differentials PLoS ONE 13 (2018)4, e0195307
6. Wainstock T, Walfisch A, Shoham-Vardi I, et al. Fertility treatments and pediatric
neoplasms of the offspring: results of a population-based cohort with a median
follow-up of 10 years. Am J Obstet Gynecol 2017; 216(3): 314.e1–314.e14
7. Faber J, Wingerter A, Neu MA, et al. Burden of cardiovascular risk factors and
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whole of population cohort study. BJOG 2017; 124: 1537–1544
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Das Nationale Gesundheitsziel „Gesundheit rund um die Geburt“: Eine Sensation
in vielerlei Hinsicht (S. 42 – 46)
U. Hauffe
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