REPORT 2021 - The Hospital Research Foundation
←
→
Page content transcription
If your browser does not render page correctly, please read the page content below
Thank you for your support of The Hospital Research Foundation Group. Together, we are having an EVEN BIGGER IMPACT SUPERCYCLE We are proud to fund research and patient care activities at the following hospitals and healthcare providers (and more): Royal The Queen Lyell Jamie Flinders Women's and Modbury South Australian Noarlunga Adelaide Elizabeth McEwin Larcombe Medical Children's Hospital Country Hospitals Hospital Hospital Hospital Hospital Centre Centre Hospital We also provide funding for lifesaving clinical and scientific research at the following research institutes and universities:
Table of contents Thank You 4 Infectious diseases 52 Highlights 6 Equipment 53 Cancer 10 Gut health and nutrition 54 Breast cancer 12 Inflammatory bowel disease 55 Prostate cancer 16 Pregnancy and birth 56 Bowel cancer 18 Proton therapy 20 Childhood disorders 58 Other cancers 22 Creative health 60 The Longest Table 24 Palliative care 64 Gift of hope 27 Volunteers 69 Under Our Roof 28 Mental health 70 Heart disease 30 Military and Emergency Services Health 71 Stroke 34 Arthritis and pain 74 Parkinson’s 35 Sleep 75 Dementia 40 Surgery 76 Aged care 42 Indigenous health 77 Diabetes 44 Country health 78 Kidney disease and pancreatitis 46 Improving care for all 80 Biospherix chamber 48 How can you join the fight? 82 Partnerships 49 COVID-19 50 | 3
THANK YOU Thank you for joining our mission for a healthy community and wellbeing for everyone With your generous support in 2021, you have brought hope to the many people fighting cancer, heart disease, dementia and more than 50 areas of medical research and healthcare. Thank you! Our promise to you: PRIVACY Always respect your privacy and never share your data with anyone. 100% of YOUR donation CONTACT Keep you updated on the impact and outcomes of your support, in the manner in which you prefer. When you give to THRF Group, 100% of your donation, plus FEEDBACK Welcome your feedback at all times. more, goes directly to research and patient care grants! This is because our administration TRANSPARENCY costs are covered by our commercial Be open and transparent with how your gifts are used, business activities which also boosts and use them carefully and cost effectively as you intend. our funds to research and patient care each year. So as a supporter, THANK YOU you can feel proud that all of your Always say thank you, no matter donation gets to the intended cause! how big or small your contribution. 4 | The Hospital Research Foundation Group Impact Report 2021
THANK YOU How you joined the fight Donations in Memory 31% Gifts in Wills Events 22% Major Giving (donations over $5,000) Monthly Giving 19% Community Fundraising (includes The Longest Table Gifts and Mercer SuperCycle) in Wills Individual 15% Individual Giving Giving Thank you! 8% Monthly Giving Community Fundraising 3% Donations in Memory Major Giving 2% Events Sadly though, a number of medical research and patient care projects miss out on funding every year. It is only together with your help that we can continue the fight for cures and improved treatments for our loved ones. We look forward to your ongoing support in 2022 and beyond. | 5
HIGHLIGHTS Disease doesn’t stop for COVID That’s why in 2021 we’ve been busier than ever fighting for your health! Proton therapy Breast cancer researcher A/Prof Phil Gregory $3.25 million for NEW cancer-fighting projects Announced a $2 million grant to the revolutionary Australian Bragg Centre for Proton Therapy and Research, plus many new projects in breast, prostate and childhood cancer. Services expand for New grants for the Parkinson’s and stroke diseases most important A Clinical Nurse Consultant joined to YOU! the team, plus an additional Exercise Provided translational grants which will Physiologist and Occupational be patient-ready sooner in heart disease, Therapist! More activity groups and dementia, aged care, mental health, wellbeing support are also available. endometriosis and more! Nurse Jo Dalton Dr Jiawen Li, (left) working with heart research client Kate grant recipient 6 | The Hospital Research Foundation Group Impact Report 2021
HIGHLIGHTS More highlights >>> COVID crisis support THRF Group's Paul Flynn with Dr David Panter, ECH Organised gifts for frontline hospital staff, plus care packs for families waiting in lengthy testing lines. SA-based research also continued, with a world-first ‘one year later’ immunology study published. New partners joined the fight! Welcomed more corporate partners in 2021 including ECH, Woodville West Torrens Football Club, Hither & Yon and the Adelaide 36ers, joining existing partners Drakes, Zorich Group and Scott Salisbury Group. Support for grassroots charities Provided significant grants to grassroots charities such as the Childhood Dementia Initiative, HAS Foundation (palliative care), Woodville West Treasure Boxes (disadvantaged families), Torrens Football Club Taboo (period poverty) and more. Adelaide 36ers Greta (middle) lives with Rett Syndrome | 7
HIGHLIGHTS Miniature horse Biospherix Chamber service saved built Secured the future of Nolton Park Opened a $1.4 million state-of-the-art Horses Healing Hearts pet therapy Biospherix Chamber to treat chronic service to bring comfort to people pancreatitis, cementing Adelaide as in hospitals, hospices and aged a leading centre of excellence for care facilities. a unique pancreatectomy and islet transplant procedure. Kimberly Bartlett with miniature horse Moét Professor Toby Coates with pancreatitis patient Chelsea Holloway Art prize inspired by healing More than 400 artworks were submitted for the inaugural Centre for Creative Health Art Prize, which had $51,000 in prizes available. All works focused on healing, with 40 finalists exhibited. Artist Jasmine Crisp with Ruby Allegra, and artist Ida Sophia (left) 8 | The Hospital Research Foundation Group Impact Report 2021
HIGHLIGHTS Dr Sharon Mascall-Dare (left), More support for and the Invictus team service members The StoryRight and MindRight programs were added to Military and Emergency Services Health Australia’s offerings, plus a $250,000 grant secured the future of the Invictus Pathways Program! Getting close to our community Launched new ‘Together.Fight.’ adverts, involving 100+ community volunteers! World-first Parkinson’s WATCH projects Scan the QR code VIDEO to watch the video Developed a world-first app for people with Young Onset Parkinson’s, plus funded research to test spider venom on live brain neurons to stop degeneration of the disease. We also loved meeting you all at our events throughout the year! | 9
CANCER Thanks to your donations our hard-working and passionate researchers can continue the fight against cancer. 10 | The Hospital Research Foundation Group Impact Report 2021
CANCER Everyone knows someone In 2021, your support extended affected by cancer. In fact, across many different cancers: nearly one in two Australians • Breast cancer will be diagnosed with cancer • Prostate cancer by the age of 85. • Bowel (colorectal) cancer • Brain cancer The good news is that survival • Childhood cancers rates are improving, thanks to earlier diagnosis, better • Leukaemia treatments and improved care • Lung cancer that is only possible with the • Neuroendocrine cancers support of people like you. • Abdominal cancers (liver, pancreas, ovarian) • Oesophageal cancer • Multiple myeloma • Cancer treating equipment • Revolutionary proton therapy Dr Zeyad Nassar and team | 11
CANCER One in seven women in Australia face a breast cancer diagnosis in their lifetime. Breast cancer Breast cancer affects mostly women over 50 years old, however it is also the most common type of cancer in young women. Thanks to you, our dedicated researchers are working hard to find new breast cancer treatments and protect those most at risk of deadly forms of the disease. Your impact in 2021: Progressed work to improve the diagnosis Educated women and influenced policy of triple negative breast cancer to about breast density and its implications enable earlier treatment options and for identifying breast cancer prevent the spread of this most deadly form of the disease Explored a number of different inhibitors which show promise in blocking a protein Found new targets for chemotherapy- called Aquaporin 1, which has been proven resistant breast cancer, focusing on a to play a key role in helping breast cancer little-known protein called Basconuclin-2 cells moving to other parts of the body Helped identify whether other medications Designed future clinical trials to test a list often being taken by breast cancer of new and existing drugs which show patients will interfere with their cancer promise in changing an offending treatment hormone receptor from cancer-promoting to cancer-inhibiting Continued investigations into a protein called Creld2, which causes breast cancer Progressed investigations into a lesser- to develop and grow more quickly, and studied physical force experienced by discovering agents which can destroy or breast cancer cells known as compressive block this protein force, to find ways to slow, stop or reverse rapidly growing cancer cells. Central Adelaide Local Health Network 12 | The Hospital Research Foundation Group Impact Report 2021
CANCER Who your donations help! At only 36 years old, Michelle (pictured) fought a terrifying battle with triple negative breast cancer – the deadliest breast cancer type. Having supported her mum through the same battle a few years earlier, Michelle endured surgeries, chemo- therapy and an intense fear of leaving behind her four-year-old son, Nate. “I felt desperate and hopeless. I just needed somebody to fix me so I could stay here for my son,” she said. Fortunately, because of your support, researchers like Associate Professor Phil Gregory (right) are on the verge of an exciting breakthrough in the treatment of triple negative breast cancer, bringing hope to women like Michelle and her family! Thank you! Do you understand what breast density is? Dense breast tissue is normal and common, but it can hide cancers and increase cancer risk. Thanks to your donations, Associate Professor Wendy Ingman has developed an animation to help women better understand breast density and how it can complicate mammogram screening. Scan the QR code to watch the video WATCH VIDEO | 13
CANCER “We can’t thank you enough for your support! Thanks to you, we’ve been able to continue our investigations into why breast cancer cells become resistant to chemotherapy and hope to use these insights to identify a new target for therapy or enhance the effectiveness of current therapies.” Dr Cameron Bracken, Centre for Cancer Biology Beverley’s loyal support Beverley is a long-term and loyal donor to The Hospital Research Foundation Group. And after a breast cancer scare in 2007, just before her 70th birthday, she saw firsthand how medical research can save lives. Thank you Beverley for your kind support! If you would like to join Beverley in the fight against deadly diseases, simply contact us on (08) 8244 1100 or visit www.HospitalResearch.org.au 14 | The Hospital Research Foundation Group Impact Report 2021
CANCER Fundraising in honour of a friend Nicole Steigen was confronted with the stark “Having just lost Tash, we knew it would be realities of breast cancer when she lost her a great opportunity to honour her memory close friend Tash, who had also left behind a and create awareness for breast cancer and husband and two young children. raise funds for research. The dress code was of course pink and on the day, it was so "What hit home the most was if anyone could rewarding seeing this massive sea of pink no have fought off cancer, it would have been matter which direction you looked.” Tash. To watch her be taken so quickly, despite all of the treatment she had undergone, was If you would like to hold a fundraiser in devastating," Nicole said. 2022, we would love to hear from you! Please contact us on (08) 8244 1100 or Nicole decided she wanted to do something to visit www.HospitalResearch.org.au help so held a Ladies Day fundraiser at her local to find out more. Nedlands Rugby Union Football Club in Perth, raising an incredible $2,200! This lifesaving research is supported through our Group charity Australian Breast Cancer Research, which is focused on the prevention, detection, management and treatment of breast cancer. www.AustralianBreastCancer.org.au a charity of THRF Group | 15
CANCER One in six Australian men will develop prostate cancer before the age of 85. Prostate cancer Advances in research have improved prostate cancer survival rates, however sadly 3,000 men still die each year from the disease. With your support, improving treatments and preventing the disease from progressing to advanced incurable stages has been a focus of our research. Your impact in 2021: Progressed pre-clinical work to improve Started developing a unique prostate the performance of common prostate cancer ‘report card’ which outlines cancer medication Zytiga, to speed up the outcomes of various treatments to the drug’s digestion and enhance help patients make informed treatment absorption in the body choices upon diagnosis Explored how prostate cancer cells Designed clinical trials for an exciting become resistant to existing therapies, with list of new and existing drugs which insights being used to identify biomarkers show promise in changing an offending for patients who may respond best to a hormone receptor from cancer- promising drug called Ribociclib promoting to cancer-inhibiting Progressed work on improving the early Supported the South Australian Prostate detection of patients whose cancer is likely Cancer Clinical Outcomes Collaborative to spread to advanced, incurable stages (SA-PCCOC) database which now holds by establishing biomarkers which can data for more than 18,000 men to distinguish high-risk patients assist research insights and inform best approaches to care. Tested a new class of drugs called CDK9 inhibitors in the hope they show promise in stopping prostate cancer from spreading Central Adelaide Local Health Network 16 | The Hospital Research Foundation Group Impact Report 2021
CANCER Maggie’s fight for all the men in her life! Dr Maggie Centenera’s research is driven by a deeply personal link to the disease. Sadly, her grandfather died with prostate cancer, and her dad and four uncles all have prostate cancer; which makes her very worried for her brother and son who are at a much higher risk. “During my dad’s cancer journey, his biggest frustration has been that his doctors aren’t definitive in how he should be treated,” she said. “Prostate cancer patients are fortunate to have a few treatment options and drugs available to them, but it is currently unclear which would work best for which patient.” “My research will focus on identifying biomarkers to determine which patients Ribociclib (a promising new drug) will work best for, in order for doctors to be better informed when making treatment decisions and ultimately improve survival rates for men with advanced prostate cancer," Dr Centenera (below) said. Kieran Anderson (above left) raised “Thank you to all an outstanding $3,680 for prostate the donors who are cancer research by shaving his supporting my work!” beard and hair in memory of his best friend Patrick. “We have known each other since we were four years old. He died at 62 after not picking up on the cancer early enough and it spread to other parts of his body,” Kieran said. “I wanted to raise awareness of the necessity to have physical checks on a regular basis. Don’t just rely on blood tests - whilst they can be a good guide, you can’t beat the physical examination.” These ground-breaking studies are supported through our Group charity Australian Prostate Cancer, which is dedicated to the detection, treatment and management of prostate cancer. www.AustralianProstateCancer.org.au a charity of THRF Group | 17
CANCER Bowel cancer (also known as colorectal cancer) affects about 15,500 men and women each year. Bowel cancer Worringly, half of all bowel cancer diagnoses will spread to the liver, where it is often unresponsive to current treatments. Thanks to you, we are improving awareness for screening, earlier diagnosis and better treatments to help prevent the disease progressing to these deadly stages. Your impact in 2021: Trialled a more personalised treatment Collaborated and analysed the outcomes approach to aggressive bowel cancer called of thousands of bowel cancer surgery Total Neoadjuvant Therapy (pTNT) with patients to learn best practice for quality 50 patients from across SA, Alice Springs, of life Broken Hill and Darwin. This included Discovered the mechanisms responsible follow-ups and data capture, to improve for some bowel cancers progressing more outcomes for these patients rapidly than others, involving a protein Funded the Jodi Lee Foundation’s called ROCK and its recruitment of white awareness campaign and workplace blood cells to form invasive tumours prevention program to increase awareness Continued to build a biobank of liver in the community of the importance of metastatic bowel cancer tissue to analyse taking a bowel cancer screening test and identify biomarkers to help predict whether bowel cancer is likely to spread. Central Adelaide Local Health Network “Our research is very patient-centred and the first question we always ask ourselves when we’re thinking about a research project is – is there a direct benefit to the next patient we see?" Associate Professor Tarik Sammour, Royal Adelaide Hospital 18 | The Hospital Research Foundation Group Impact Report 2021
CANCER “I was very lucky because even though the tumour was a decent size, it wasn’t very advanced and hadn’t spread to the gut or the lymph system.” How the poo test saved Clive’s life! Professor Clive Prestidge is a self-proclaimed “poster boy” for the poo test. Three years ago he received a positive result from “I was very lucky though because even though the bowel cancer screening kit mailed to over the tumour was a decent size, it wasn’t very 50s, which triggered him to see his GP and have advanced and hadn’t spread to the gut or the a further colonoscopy. lymph system.” “I wasn’t worried at first because Now, having won his personal battle against those poo tests can bring a lot of cancer, he can continue the fight where he is more comfortable – in the lab conducting world- false positives… but I got my results leading cancer research. He also represented his back and they said they’d found a journey in our 2021 ‘Together Fight’ commercials. tumour in my bowel,” he said. “Cancer diagnoses are unfortunately increasing, “My life was thrown completely upside down. but with research, we can play a role in saving Three weeks later I was having surgery, a full hemi- people’s lives. And that’s what ‘Together Fight’ is colectomy where I had half my colon removed. all about,” he said. | 19
CANCER Proton therapy given $2 million boost Imagine being a young person with cancer in the brain or spine, and the best treatment option is only available on the other side of the world? Soon, this will be a thing of the past with Adelaide set to become home to the first proton therapy centre in the southern hemisphere. The Australian Bragg Centre for Proton Therapy and Research will transform the way cancer is treated, particularly for young people whose rapidly growing and developing cells are more susceptible to damage from radiation. Due to open in 2023, the facility will see about 800 patients a year. And with your kind donations, The Hospital Research Foundation Group has contributed $2 million to the centre’s critical start-up operations! Thank you! How does proton therapy work? Who will it benefit? Proton beam therapy is a type of radiotherapy Nurse Kate Pagnozzi was that targets tumours with high-energy, positively 20 years old when she charged particles (protons). It is a more precise discovered “out of the blue” alternative to X-ray (photon) radiation therapy, she had a tumour the size of which is more commonly used to treat cancers. a tennis ball in her brain. The precise nature of proton therapy, with the Brain surgery removed 98% of the tumour, but 18 ability to target cancer cells at a specific depth months later she received the frightening news inside the patient, means there is less radiation that the tumour was growing again. With options delivered to healthy tissue surrounding the exhausted locally, Kate did her own research and tumour. found state-of-the-art proton therapy available in the United States. This enables treatment with less side effects for paediatric, adolescent and young adult patients “Having proton therapy in Adelaide and those with rare cancers. will be a game-changer,” Kate said. Scan the QR code to see how proton therapy works “People will no longer have to pack their entire belongings and move halfway across the world to access this life-changing treatment.” WATCH VIDEO 20 | The Hospital Research Foundation Group Impact Report 2021
CANCER What will the $2 million go towards? Key medical specialists will be recruited as part Some of the specialists have already started of a $1.4 million grant over three years, including (pictured above with Paul Flynn, THRF Group a Clinical Project Manager, Medical Physicist, CEO). They are thrilled to be part of the team Radiation Therapist, Paediatric Medical transforming the cancer treatment landscape Oncologist and part-time Radiation Oncologist in Australasia! for the SAHMRI-based facility. A further $628,000 over two years will establish the Australian Proton Therapy Clinical Quality Registry. The registry will collect and record cancer treatment details and patient outcomes from across the country, providing further information on the types of cases that would benefit from proton beam therapy. How you can help! Monthly giving is one of the simplest ways you can support Scan the QR code lifesaving research and patient care like revolutionary to learn more proton therapy. By choosing a tax-deductible amount to LEARN give each month, you will help provide a consistent stream MORE of funding our researchers can count on! Learn more at www.HospitalResearch.org.au | 21
CANCER Cancer does not discriminate. It affects people of any age and background. Fighting rare and common cancers We are proud to fight against many rare and common cancers, across children and adults, to give hope through research, care and equipment to everyone suffering from these awful diseases. Your impact in 2021: Childhood cancers Neuroendocrine cancer • Supported research into new therapeutic • Supported the treatment and ongoing targets for young children with high-risk evaluation of patients with neuroendocrine neuroblastoma, as an important alternative tumours, including an important data registry to current toxic treatments which have side which captures clinical and quality-of-life effects that often leave them with life-long information on recipients of LuTate therapy. impairments • Started developing an online tool to enhance Abdominal cancers routine follow-up care for children recovering • Delivered six applications of pressurised from solid cancers and better manage their intraperitoneal aerosol chemotherapy (PIPAC) ongoing quality-of-life assessments for patients with bowel, ovarian, stomach and • Completed important immune profiling for a pancreatic cancers. new CAR T-cell therapy to progress to phase 1 clinical trials in children with diffuse intrinsic Lung cancer pontine glioma (DIPG). • Continued research into ways to inhibit a family of 14-3-3 proteins which are found in abnormally Blood cancers high numbers in lung cancer cells. • Made significant findings in ways to starve cancer cells to death, particularly cancer Brain cancer cells with IDH1 gene mutations such as IDH1- • Continued pre-clinical trials on a new mutated leukaemia CAR T-cell therapy for adults and children • Continued to investigate new targeted with relapsed Glioblastoma. therapies for acute myeloid leukaemia (AML), with promising results for a specific SK1 Indigenous cancer care enzyme inhibitor showing to kill AML cells • Supported an Aboriginal Cancer Healing Centre • Recruited 80 newly-diagnosed multiple to improve the uptake of services closer to myeloma patients to participate in a study people’s home communities, their health and life focused on a protein called DSG2 which is expectancy outcomes, with an evidence-based, thought to be overexpressed in patients with cost-effective community-approved model. the poorest prognosis. 22 | The Hospital Research Foundation Group Impact Report 2021
CANCER TQEH team saving lives: A/Prof Gabrielle Cehic AM, Jessica Mercurio and Davina Nicholls 10 years of life-changing cancer treatment 2021 marked 10 years of Lutetium Octreotate (LuTate) therapy being available in South Australia for people with neuroendocrine tumours (NETs). LuTate is a targeted internal radiotherapy treatment for NETs, given intravenously (via a drip) to help deliver a targeted high dose of radiation directly to the cancer cells. More than 177 treatments have been delivered to patients at The Queen Elizabeth Hospital during this time – helping people like Tayla (pictured left), who was first diagnosed at just 12 years old, live a better life! | 23
CANCER Thank you from our ambassadors The Longest Table raises $303,886 Thank you to all of the outstanding Longest Table hosts who raised $303,886 for cancer research in 2021! Cancer doesn’t stop for COVID-19 and our passionate Forkstars held a fantastic array of events to #ForkCancer within their communities. Ambassadors Adelady and G-Fresh held their fourth consecutive event and raised an incredible $55,000! Loyal hosts Trish Fuss, Sarah Waldron and Michelle Mackman, along with first-time hosts Estelle Green and Erin Launer, each raised exceptional totals of Jo Lambrakis over $16,000 in honour of their loved ones. Thank you to everyone who participated! Big or small, your donation makes a huge difference to the cancer projects supported by The Hospital Research Foundation Group. You can help too! The Longest Table is THRF Group’s annual cancer fundraiser where you and your friends get together for a night of food, fun, friendship and fundraising to save lives from cancer. You too can host a Longest Table in 2022 – visit www.TheLongestTable.com.au to find out more! 24 | The Hospital Research Foundation Group Impact Report 2021
Cancer Thank you to our outstanding Longest Table hosts who raised a record $303,886 for cancer research in 2021! Thank you to all of our hosts! | 25
CANCER Furry fighter Arlo comforts people with cancer Meet Arlo, one of our cutest and proudest ambassadors! Arlo is a cancer therapy dog who loves visiting patients and hardworking hospital staff to brighten up their day. He has already saved one life, that of his owner Nick, who recently battled an aggressive tongue and throat cancer which also took a big toll on his mental health. Now they work together to bring joy to people who are undergoing treatment for cancer. Arlo is becoming a huge celebrity in his own right – amassing a huge Instagram following at @arlo_the_cancer_service_dog He is also selling his own doggie bandanas to raise money for THRF Group! If you’d like to purchase a bandana or support Arlo’s fight, learn more at www.arlo.raisely.com Scan to check out the full Arlo SUPPORT merch range ARLO 26 | The Hospital Research Foundation Group Impact Report 2021
HOPE “I’ve been through quite a few health issues myself and with our family, so with this gift, maybe we can avoid a few of these things in the future.” Barry Hankins, 75, and wife Wendy The gift of hope for future generations “I see the value of medical research as clinical trials kept my son alive for five more years. I won’t always Leaving a gift in your Will is one of be here, so leaving a gift in my Will allows me to help future generations.” the most significant ways you can Sylvia Bridgman, 91 have an impact on the health and wellbeing of future generations. A charitable bequest ensures you will be You will also be joining our esteemed Basil remembered as someone who is committed Hetzel Society, made up of generous and to helping others. compassionate people like yourself who value medical research. Your Will should always take care of your loved ones first. However after this, you may People like Sylvia Bridgeman, Barry Hankins wish to leave a gift to The Hospital Research and wife Wendy who are profiled above. As Foundation or the charity within our Group members of our Basil Hetzel Society, they also you feel most connected to. enjoy special events throughout the year to learn about the impact of their gifts. A gift of as little as 1% of your estate can make a big difference to lifesaving medical research For more information about leaving a lasting and patient care in hospitals. legacy through a gift in your Will, speak to one of our friendly team members on (08) 8244 1100. | 27
UNDER OUR ROOF Even more regional cancer patients helped in 2021 More country cancer patients are being helped than ever before through our Under Our Roof accommodation! Four homes were available for the first time in 2021 thanks to the opening of two family-style apartments at Bowden, joining two existing homes at Woodville West. This allowed 20 cancer patients and their families or support networks to stay in 2021 – the most we’ve ever had! It brings the total number of patients helped since 2016 to 80. Under Our Roof offers family-style accommodation to country cancer patients travelling to Adelaide for their treatment. A huge thank you to the riders and support crew from the Mercer SuperCycle multi-day cycling event, who raised more than $2.8 million over 10 years towards Under Our Roof. We couldn’t have done it without you! 10 years, four homes and $2.8 million! That’s the incredible achievement of the team from Mercer SuperCycle – a multi-day charity bike ride around regional South Australia. More than $270,000 was raised in 2021 – the ride’s 10th year – to bring the total to $2.8 million! Thank you to everyone who has made this possible! You are truly changing the lives of cancer patients and their families now and into the future. 28 | The Hospital Research Foundation Group Impact Report 2021
UNDER OUR ROOF Cancer doesn’t stop for COVID All four Under Our Roof homes were fully Lisa was finishing her final week of treatment occupied during South Australia’s COVID-19 when the lockdown hit, but was able to finish lockdown in July 2021 – much to the her treatment and get a medical exemption to appreciation of patients. travel home to be with her partner and three daughters. This included Mount Gambier mother Lisa Hawkins who stayed in one of the new homes “It’s such a stressor trying to think of a place to in Bowden during her three-week radiotherapy stay while dealing with a cancer diagnosis and treatment for breast cancer, along with her these homes definitely ease that burden for sister Tracy for support. rural cancer patients,” Lisa said. Mercer House Dr Jones & Partners House Mercer Apartment These three homes are kindly supported by our sponsors: If you would like to partner with us, chat to our friendly team on (08) 8244 1100 or visit www.HospitalResearch.org.au | 29
HEART DISEASE Heart disease is Australia’s biggest killer, with someone dying from the disease every 12 minutes. Working hard to beat heart disease More than four million Australians live with a cardiovascular disease, with many of the risk factors preventable. Thanks to your support, we are working hard to stop you or your loved ones from falling victim to heart disease. Your impact in 2021: Progressed the development of the Continued to analyse sleep data in world’s smallest 3D printed catheter people with obstructive sleep apnoea to to improve the diagnosis of heart determine whether wearing a CPAP mask blockages in narrow arteries can reduce the risk of them developing AF, with promising early results Expanded a world-leading clinical trial into the care provided to people Continued managing a biobank to with atrial fibrillation (AF), through the enhance cardiovascular research ongoing delivery of a personalised and and identify biomarkers responsible integrated “iCare” clinic for heart disease to aid more research Evaluated how many patients Studied whether sub-clinical AF continue to experience chest pain is associated with risks of dementia after elective coronary stenting to and whether the screening guidelines gain important insights into best care for AF need to be adapted and avoid unnecessary complications Progressed research to identify predictors Assessed whether an aggressive for which patients are at risk of an approach to weight and lifestyle emergency tear in the aorta during surgery management can decrease AF to greater inform treatment options symptoms and reduce hospitalisations Improved care and outcomes of patients Recruited participants to trial a diabetes with cardiac implantable electronic drug which shows promise in treating AF devices by investigating additional areas of service delivery and new technology. Central & Northern Adelaide Local Health Networks 30 | The Hospital Research Foundation Group Impact Report 2021
HEART DISEASE New tech to find heart blockages in narrow arteries In a huge breakthrough for diagnosing heart blockages, the world’s smallest 3D-printed catheter is being developed to enable the high-quality imaging of narrow arteries! Thanks to your donations, we are proud to be supporting teams from the University of Adelaide and Royal Adelaide Hospital to progress the micro-catheter technology which will be able to detect cholesterol crystals which accumulate in the fatty plaques that form in heart arteries. Designed by engineer and inventor Dr Jiawen Li (pictured), the device could be a game-changer in helping prevent coronary artery disease! Thank you Zorich Group for fundraising for heart research in 2021! If you or your business would like to give back to a disease area close to your heart, contact us on (08) 8244 1100 or visit www.HospitalResearch.org.au Our mission to beat heart disease is enhanced by our Group charity Australian Heart Research which is focused on prevention strategies, treatment and hospital care for patients with heart disease. www.AustralianHeartResearch.org.au a charity of THRF Group | 31
HEART DISEASE Do you experience heart palpitations or shortness of breath? If you do, you could be at risk of atrial fibrillation (AF) – a dangerous heart arrythmia characterised by a rapid and irregular heartbeat, and causing issues such as fainting, dizziness and chest pain. Danny Daminato thought he was just unfit WATCH when he was often out of breath. Danny’s story! Instead, he was diagnosed with AF and needed immediate surgery. He and wife Sandy are now managing his condition through lifestyle changes and regular check-ups. WATCH Your donations are vital to helping us find new VIDEO ways to treat and prevent AF to save the lives of people like Danny. Thank you! 32 | The Hospital Research Foundation Group Impact Report 2021
HEART DISEASE Landing the knockout blow against atrial fibrillation! Cardiologist Associate Professor Chris Wong has spent a lifetime training for the fight – the fight against deadly heart condition atrial fibrillation (AF). With you in his corner, he now has the power to land the knockout blow! He is conducting a clinical trial of a new drug to treat AF’s common risk factors of high blood pressure, excess weight and diabetes. He hopes that by focusing on prevention, rather than treatment, then the deadly risks and complications arising from AF will be eliminated. He was also happy to give back and volunteer his time for THRF’s 'Together Fight' campaign. “Medical research benefits us all, we will all be affected by disease at some point in life. Volunteering was the least I could do for an organisation that has supported researchers like myself and others.” | 33
STROKE One person has a stroke every 10 minutes Stroke care, services in Australia. and research expand Stroke often attacks without warning, rapidly killing two million brain cells every minute and highlighting the huge need for support in stroke prevention, treatment and recovery. In 2021, we are proud to have increased our focus on stroke through a merger with Stroke SA. Our new division The Hospital Research Foundation Group – Stroke is committed to enhancing patient care, services and world-leading research for people impacted by stroke. In 2021, our care team and researchers: Provided allied health services Continued investigations on what causes (occupational therapy, counselling and Transient Ischaemic Attacks (TIA), or mini nurse consultations), specialised support strokes, to develop a diagnostic test for groups, social activities, exercise and TIAs which could prevent a major stroke education sessions for people impacted by stroke and their support networks Progressed the Adelaide Stroke Incidence Study to identify stroke trends in Adelaide Participated in world-leading clinical and evaluate future care and resource trials which focus on stroke treatment in allocation, recruiting 300 patients a year the hyper-acute phase using advanced clot-busting medication, as well as the Continued the investigation and optimal subacute phase, secondary prevention model of a regional stroke coordinator to and recovery improve stroke outcomes in rural SA Investigated an algorithm for predicting Prepared for a study involving therapy dog stroke recovery to assess whether it visits to the RAH’s Stroke Unit to improve would help allied health professionals the mood of stroke patients, their visitors provide optimal therapy for patients and stroke unit staff. Central, Southern & Regional Local Health Networks Together with our charity extension The Hospital Research Foundation Group – Stroke, we are committed to improving the prevention, diagnosis, acute treatment, care and ongoing support of people impacted by stroke. www.stroke.org.au a charity of THRF Group 34 | The Hospital Research Foundation Group Impact Report 2021
STROKE/ PARKINSON'S Meet our Stroke and Parkinson's allied health team! To access these services, please call: For the first time, The Hospital Research Foundation Group is Stroke expanding its scope to deliver allied health services to the community. (08) 8352 4644 Parkinson’s This includes occupational therapy, counselling and nurse (08) 8357 8909 consultations for people impacted by stroke and Parkinson’s. Olivia Nassaris Tamika Perrott Executive Director Social Worker Olivia is a hands-on director, assisting clients in Tamika provides counselling for clients and their care and wellbeing and continually their families, helping with trauma, stress, improving the support and services on offer. relationships, building confidence and wellbeing. Simone Ridge-Cooke Joanne Dalton Client and Community Clinical Nurse Consultant Engagement Manager Jo offers clients a compassionate and holistic Simone coordinates all our valued group health assessment, culminating in a personalised programs, such as art classes, singing groups, care plan and ongoing advice and care. and more both in Adelaide and across the state. Christian Burden & Toby Yeung Hannah Tavian Speech Therapist Occupational Therapists Christian and Hannah help maximise choice Toby treats speech, language and swallowing and independence through a complex challenges to help clients maintain their assessment of client needs, service communication, relationships and overall wellbeing. development and interventions. Tayla Haslam & Narelle Lee Sophie Edwards Wellbeing Officer Exercise Physiologists Responsible for client education and support, Tayla and Sophie love helping clients Narelle assists clients to better manage their achieve their fitness and cognitive goals condition and access appropriate support. through Brain x Body Fitness Studio’s popular, evidence-based exercise programs. | 35
PARKINSON’S Did you know one Australian is diagnosed with Parkinson’s every three hours? Living well with Parkinson’s Parkinson’s can affect anyone, from all walks of life. But with the right team, you can live well with Parkinson’s! The Hospital Research Foundation Group – Parkinson’s (formerly Parkinson’s SA) is committed to providing support, education, services and research for those living with the progressive neurodegenerative disorder. In 2021, our care team and researchers: Provided allied health services Investigated whether faecal transplants (occupational therapy, counselling and can help ease the symptoms of Parkinson’s nurse consultations), specialised support by improving people’s gut health and groups, social activities, exercise and addressing areas such as constipation education sessions for people living with Parkinson’s and their support networks Released a world-first app and website to support people with Young Onset Supported new research aimed at preventing Parkinson’s (aged under 50) called YOP-X the degeneration of Parkinson’s by investigating whether spider venom can help Established an SA-first MRI imaging restore and repair brain cell energy levels centre which specialises in advanced F-DOPA scanning to facilitate research Progressed trials into Infrared Light Therapy for Parkinson’s disease as a promising treatment for Parkinson’s to improve gut microbiome and symptoms Delivered health and wellbeing programs including balance, gait, cognition and fine and specialised neuro-physiotherapy, motor skills crisis counselling, wellness coaching and occupational therapy to people living with Parkinson’s and those on the NDIS in regional areas. Australasian Central Adelaide Research Local Health Institute Network “The support from the whole team has been extraordinary. You couldn’t ask for a better service.” Kate, newly diagnosed with Parkinson’s 36 | The Hospital Research Foundation Group Impact Report 2021
PARKINSON’S Can spider venom be used to treat Parkinson’s? A cure or ways to stop the progression spend on the business-as-usual activities such as of Parkinson’s is the holy grail of research repairing themselves,” A/Prof Bardy said. into the disease. “Artificially raising the energy in brain cells is not Now, thanks to your contribution to a global easy, but what if we could give the cells a break research and funding collaboration also involving from too much activity? A few hours break each the Michael J. Fox Foundation and Shake It Up day could be enough to give these brain cells a Australia, this holy grail could be one step closer! chance to restore their energy levels and repair themselves from all the extra work.” Adelaide neurobiology expert Associate Professor Cedric Bardy is leading a trial This is where natural venoms come in, which which aims to address the ‘tug of war’ that is have shown to be full of ion channel modulators experienced by the brain neurons of people with that could be effective in re-prioritising cellular Parkinson’s. signalling. “In Parkinson’s disease, fewer dopamine cells are If successful, a therapeutic breakthrough left behind to do the work of thousands of cells that can slow down neurodegeneration in that died too early. This in turn stresses those Parkinson’s disease will change the lives of remaining cells and gives them less energy to millions of people worldwide! | 37
PARKINSON’S Brain x Body Fitness Studio The Brain x Body Fitness Studio at Unley is the first exercise physiology service of its kind to focus on body and brain health through exercise and encourage neuroplasticity. Neuroplasticity is the ability of the brain to grow and change in response to physical and mental activities throughout life. By consistently challenging the brain with exercise and fresh mental activities, the brain continues to restructure, rewire and build new connections – perfect for people with movement disorders but also anyone advancing in age. Run by our Parkinson’s team, it is particularly useful for people with a neurodegenerative disorder like Parkinson’s and those recovering from stroke. Want to become a member? Call 0499 088 725 or visit www.bbfs.com.au Good news! A new Brain x Body Fitness Studio will be opening in Woodville in 2022! 38 | The Hospital Research Foundation Group Impact Report 2021
PARKINSON’S Brain and body fitness a game-changer for Crows champion WATCH his journey Adelaide Crows inaugural Club Champion Mark Mickan knows the benefits of regular WATCH exercise. But when he was diagnosed with VIDEO Parkinson’s in 2016, he struggled to find the motivation to stay active. That was until he found the Brain x Body Fitness Studio at Unley. “It’s really special coming here, everything’s geared towards your own situation. This place has been a saviour, not only for myself but for everyone else who comes here too.” In the prime of his life As a father-of-two and successful school principal, Todd Murfitt was only 35 years old when he was suddenly diagnosed with Young Onset Parkinson’s (YOP). With no known family history of the disease, Todd had mistakenly attributed his initial tremors to stress and drinking too much coffee. “It's not easy to hear you've been diagnosed with what is commonly perceived as an ‘old “An elderly person diagnosed with person's disease’, especially when you're in the Parkinson's is in a very different stage of prime of your life,” Todd said. life compared to a person living with YOP. The YOP-X app, which brings all of this There was a distinct lack of information information together, will become a go-to available for people with Young Onset resource for people with YOP.” Parkinson’s, so when Todd was asked to participate in developing the world-first YOP-X Search YOP-X in your app store or visit app, he knew it would be life-changing. www.YoungOnsetParkinsons.org.au We’re proud to be providing support and information to people living with Parkinson’s and other movement disorders, their carers, family, community and health professionals through The Hospital Research Foundation Group – Parkinson’s. www.FightingParkinsons.org.au a charity of THRF Group | 39
DEMENTIA An estimated 472,000 people live with dementia in Australia, and a further 1.6 million people care for someone with the progressive condition. Helping our loved ones with dementia While the fight for a cure continues, research focusing on the prevention and care of people with dementia can also help the many families dealing with this devastating disease. Your impact in 2021: Supported a state-wide screening clinic Planned the upgrade of the Whittaker to allow South Australians at risk of dementia ward at Noarlunga Hospital dementia more access to clinical trials to provide a more adaptable space and early diagnosis which caters for the special needs of people with dementia Helped people who are newly diagnosed with dementia to ‘take charge’ of Progressed the design of new trauma- their condition, with evidence-based informed guidelines to improve care interventions for the first few weeks and in hospitals for people with dementia, months following diagnosis and also for reduce patient distress and prevent the long-term challenging behaviours Commenced a project to help older Continued an evidence-based ‘Eat adults reduce their likelihood of getting Walk Engage’ program in hospitalised dementia, including guidelines on sleep, elderly people to improve their health diet and physical activity outcomes, particularly in regards to delirium and functional decline. Continued research into whether a common heart disorder is associated with a higher risk of dementia and whether screening guidelines need to be adapted Central, Northern & Southern Adelaide Local Health Networks 40 | The Hospital Research Foundation Group Impact Report 2021
DEMENTIA Can you prevent dementia? Yes, according to the latest research! “How people use their time (ie. sleeping, sitting, being physically active) and what they eat can increase or decrease their future dementia risk,” Dr Ashleigh Smith said. Dr Smith and her team are co-developing “Previously, these factors have been a ‘Your Best Day’ tool to be used by older considered independently – but they adults and their primary care team to are not independent. Instead, daily provide tailored, evidence-based and activity and diet interact with each personalised dementia prevention advice. other to influence dementia risk. Thank you for supporting this important tool! New dementia screening clinic improving care Thanks to your support, a new state-wide screening clinic is available for people to access the latest dementia treatments and early interventions. The SAHMRI-based clinic offers state-of-the-art diagnostic scans, which can help detect people at risk of Alzheimer’s 15 to 20 years before symptoms appear! More than 100 people have already been screened by the clinic, which is part of the national Australian Dementia Network (ADNet). THRF Group has provided a $106,000 grant to support the clinic, where people undergo MRI and PET scans, interviews, neuropsychological assessments, blood collection and a discussion of personal results and a potential referral to clinical trials. Contact (08) 8128 4202 or adnet@sahmri.com for more information. | 41
AGED CARE With people living longer, our quality of life as we age has never been more important. Living your best life as you age Your support has been vital in helping fund projects which enhance the physical, social and mental health of older Australians and help reduce their time spent in hospitals or care. Thank you! Your impact in 2021: Supported older people’s transition Improved aged care residents’ access to from hospital to home through a trial rehabilitation following a hip fracture to at the RAH which delivers person-centred improve their long-term outcomes follow-up care after an unplanned presentation or admission Investigated whether a Mediterranean diet can have a positive impact on the health Evaluated the care and services delivered of people in residential aged care by ECH’s new short-stay and respite Care Hotel to determine if it can prevent hospital Investigated the health economic admissions and improve patient outcomes implications of aged care quality and safety Continued to evaluate the wellbeing of people in aged care through the Registry Continued healthy ageing research of Older South Australians (ROSA), and developed a frailty-risk index to informing key policies within the Royal inform the equitable and effective Aged Care Commission provision of health services. Central & Southern Adelaide Local Health Networks 42 | The Hospital Research Foundation Group Impact Report 2021
AGED CARE ECH partnership focusing on healthy ageing In 2021, we were proud to begin a partnership with ECH to pioneer new technologies and models of care for older Australians. At the heart of this is the evaluation of ECH’s new Care Hotel at College Grove, Walkerville (pictured above), which provides a range of options for short-term care and respite needs. The Care Hotel, named Dandelion, is the first of its kind in Australia and aims to change the landscape of how people can be supported as they age. Providing a similar experience to a hotel stay, it has been specifically designed to challenge the current limitations in existing care models, minimise hospital visits and to empower and treat people as individuals. Do you or a loved one live in an ECH community or use their services? Contact us on (08) 8244 1100 or visit www.HospitalResearch.org.au to find out ways you can support this work. THRF Group CEO Paul Flynn and ECH CEO Dr David Panter | 43
DIABETES It is estimated 280 people develop diabetes each day in Australia, contributing to one of the nation’s most concerning health issues. Reducing the diabetes burden With many serious health problems linked to diabetes, we are committed to finding new ways to treat and prevent diabetes and ultimately eliminate this disease from our community. Your impact in 2021: Continued making advancements in 3D Progressed insights into how ‘good printing islet cells for transplant into people cholesterol’ or high-density lipoproteins with severe Type 1 diabetes, to avoid the improved wound healing in diabetics reliance on a deceased donor Showed positive results in whether Found a promising new target to promote bitter supplements can reduce people’s blood vessel growth in people with diabetes appetites and become a therapy for Type 2 who are more prone to impaired wound diabetes and obesity healing and amputations Continued research into time restricted Discovered how telehealth can improve eating (also known as intermittent fasting) the treatment of chronic foot wounds for and whether it can prevent Type 2 diabetes diabetics in rural and remote areas, to help reduce the disproportionately higher rates Conducted important phenotyping of amputation in these areas work and community engagement to address diabetes inequality in Indigenous Discovered that low-calorie sweeteners Australians actually worsen blood glucose levels in patients with Type 2 diabetes, rather than Continued studies into life-threatening alleviate them diabetic ketoacidosis (when a person’s blood sugar is very high and acidic ketones build up to dangerous levels in the body) for people undergoing surgery. Central Adelaide & Regional Local Health Networks 44 | The Hospital Research Foundation Group Impact Report 2021
DIABETES Did you know? Worldwide, a limb is amputated every 30 seconds because of diabetes. This is a very scary statistic, but one PhD student Emma Solly (right) hopes to fix by finding new ways to help the body grow new blood vessels – a process which is often hampered in people with diabetes. Thanks to your support, she is targeting a microRNA called miR-181c that has shown promise in regulating blood vessel growth but has not yet been tested in diabetes. Home Lottery boosts funds to research and healthcare Thank you to all our ticket buyers in The Hospital Research Foundation Home Lottery! Proceeds from the Home Lottery go directly to funding medical research and improved healthcare initiatives across all public hospitals and communities in South Australia. You can feel proud knowing your support makes a huge impact to the health and wellbeing of our community. Thank you! | 45
KIDNEY DISEASE People with chronic AND PANCREATITIS kidney disease face many life-long health battles. Better treatments for kidney disease and pancreatitis Kidney disease can be caused by genetic factors or conditions such as diabetes, pancreatitis and high blood pressure. Together with your support, we can enable new and better treatments to those suffering from these debilitating conditions. Your impact in 2021: Established a state-of-the-art Biospherix Investigated various diet recommendations Chamber in Adelaide to enable faster and to improve the overall gut health in kidney safer Total Pancreatectomy with Islet Auto transplant recipients and prevent diarrhoea Transplantation (TP-IAT) procedures to cure immediately after transplant people of debilitating pancreatitis Finalised research into the prevalence of Supported women with kidney disease to hereditary pancreatitis and its gene profile overcome their challenges to become mothers and will use these insights to lobby for TP-IAT to be added to the Medicare Delivered key milestones in research which Benefits Schedule aims to reduce the need for anti-rejection medications for transplant patients Discovered people who are deficient in the gene Nedd4-2 are more prone to kidney Progressed ways to improve the dialysis disease particularly when their salt intake experience for patients and support a is excessive. sustainable renal nursing workforce Central, Southern & Regional Local Health Networks As part of THRF Group, Kidney, Transplant & Diabetes Research Australia supports medical research aimed at developing new therapies to enhance organ transplantation, treat diabetes and kidney disease, and ultimately eliminate these diseases. www.KidneyDiabetesResearch.org.au a charity of THRF Group 46 | The Hospital Research Foundation Group Impact Report 2021
You can also read