PLASMED X: COMPACT TUNABLE X-RAY SOURCE - Simon Bohlen, Theresa Brümmer, Florian Grüner, Martin Meisel, DESY Indico

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PLASMED X: COMPACT TUNABLE X-RAY SOURCE - Simon Bohlen, Theresa Brümmer, Florian Grüner, Martin Meisel, DESY Indico
7th Matter & Technology Meeting | 02.02.2021

PLASMED X: COMPACT TUNABLE X-RAY SOURCE
           Simon Bohlen, Theresa Brümmer, Florian Grüner, Martin Meisel,
 Lucas Schaper, Theresa Staufer, Jon Wood, Kristjan Põder, Jens Osterho
                                                    Research Group for Plasma Wake eld Accelerators
                         Deutsches Elektronen-Synchrotron DESY, Machine Division, Hamburg, Germany

                        Accelerator Research and Development, Matter and Technologies
                    Helmholtz Association of German Research Centres, Berlin, Germany
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PLASMED X: COMPACT TUNABLE X-RAY SOURCE - Simon Bohlen, Theresa Brümmer, Florian Grüner, Martin Meisel, DESY Indico
A new light source for XFI
Innovation Pool project to unlock the many bene ts of XFI

> X-Ray Fluorescence Imaging (1) provides key advantages
  > High X-Ray energy reduces dose
  > No false positives
  > Excellent spatial resolution
  > Ability to functionalise nanoparticles
> X-Ray beam must be low divergence, narrowband, bright
  > Microfocus tubes: high divergence and bandwidth
  > Synchrotrons: inaccessible scale and cost
  > …?                                                                          10 0
> Compact and a ordable X-ray source required!
> PLASMED X project
  > BMBF InnovationPool, 2019-2020                                              10 -1

                                                                 Transmission
  > Demonstrate an all-optical X-Ray source for XFI of a mouse
    phantom
                                                                                10 -2
                                                                                                                             1 cm
                                                                                                                             5 cm
                                                                                                                             10 cm
                                                                                10 -3
                                                                                        10 1                          10 2
                                                                                               Photon energy / keV
   (1)   Grüner et al, Sci Rep 8, 16561 (2018)                                                                                                           2
                                                                                        Dr Kristjan Põder | 7th, Virtual MT Meeting | 02.02.2021 | Page 00
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PLASMED X: COMPACT TUNABLE X-RAY SOURCE - Simon Bohlen, Theresa Brümmer, Florian Grüner, Martin Meisel, DESY Indico
The PLASMED X light source
A unique combination of novel technologies results in a peerless light source

> Laser driven electron source - ultra-compact
> Plasma based electron optics for beam manipulation                                                                                         X-rays
  > Allows for restricted bandwidth and tuning
                                                                                                                                 n et
  > Very strong focussing elds - ultra-compact                                                                                ag
                                                                                                                         le m
> Thomson scattering for X-ray generation                          Scattering laser                                 i p o
                                                                                                                  D
  > Undulator with a period of microns - ultra-compact
  > X-ray energy predominantly determined by electron
    beam
  > Radiation with low divergence

                     LPA laser
                                                 Active plasma
                                                      lens

                                                                                      2
                                      Plasma                              2 (1        cos ↵)                                        2
                                      source                     ~! = ~!L                    ⇠ 4                                        ~!L
                                                                          1 + a20 /2 + 2 ✓2
                                                                                                                                                3
                                                                               Dr Kristjan Põder | 7th, Virtual MT Meeting | 02.02.2021 | Page 00
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PLASMED X: COMPACT TUNABLE X-RAY SOURCE - Simon Bohlen, Theresa Brümmer, Florian Grüner, Martin Meisel, DESY Indico
Compact, narrowband, tunable X-ray source
First demonstration of LPA and APL combination for X-ray generation

> Commissioned a robust laser plasma accelerator electron
  source (1)
  > Stable operation over 8 h demonstrated
> Developed theoretical concept showing bandwidth
  narrowing (2) and tuning (3) with active plasma
                                           a      lens (4)

> Constructed proof-of-principle machine with APL enabled                                   Compton
  spectrum control                                                                         interaction

  > First demonstration of restricted bandwidth! (5)
  > First demonstration of X-ray tuning (5)                                  Plasma lens

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     (1) Bohlen et al, in preparation
     (2) Brümmer et al, PRAB 23 (2020)
     (3) Brümmer et al, in preparation
     (4) van Tilborg et al, PRL 115 (2015)
                                                                                                                                                                 4
                                                                                                Dr Kristjan Põder | 7th, Virtual MT Meeting | 02.02.2021 | Page 00
     (5) Meisel et al, in preparation
PLASMED X: COMPACT TUNABLE X-RAY SOURCE - Simon Bohlen, Theresa Brümmer, Florian Grüner, Martin Meisel, DESY Indico
Successful detection of uorescence signal
PLASMED X source shown to excite uorescence in medically-used nanoparticles

> Proof-of-principle experiments with the PLASMED X
  source
  > Detection of uorescence from gold nanoparticles
  > Detection of uorescence from gadolinium
    nanoparticles
> XFI imaging of mouse phantom upcoming
  > Foreseen in Q1 2021
> Custom-designed detectors to be tested in Q2 2021

                                                                                                                                  5
                                                                 Dr Kristjan Põder | 7th, Virtual MT Meeting | 02.02.2021 | Page 00
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PLASMED X all-optical X-ray source for XFI
  Successful demonstration of compact tunable light source for medical imaging

> Proof-of-principle demonstration of an all-optical X-Ray
  source for XFI on a mouse phantom
  > BMBF InnovationPool 2019-2020
  > Aim to continue with 3rd party technology-transfer funding
> Robust laser plasma accelerator electron source commissioned
> Successfully detected uorescence from medically-used
  nanoparticles
> First demonstration of bandwidth narrowing and tunability by an
  APL
> Custom-designed X-ray detectors from KIT to be tested Q2 2021
> Next step: Imaging of mouse phantom
> Future: high rep rate implementation @ KALDERA

                                    2 2 (1      cos ↵)      2
                           ~! = ~!L                    ⇠4       ~!L                                                                    6
                                                                      Dr Kristjan Põder | 7th, Virtual MT Meeting | 02.02.2021 | Page 00
                                    1 + a20 /2 + 2 ✓2
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